Digital Commons Network^™

The Invisible Disease Made Visible: A Qualitative Inquiry Into The Lived Experience Of Cold Agglutinin Disease Patients, Paul Mowry

Electronic Theses and Dissertations Archive

The purpose of the phenomenological study was to better understand the lived experience of Cold-Agglutinin Disease (CAD) patients. Eleven white female participants who had moderate to severe symptoms of CAD were recruited via a CAD support group on Facebook and were prompted with a series of open-ended questions about their lived experience with CAD. Interview questions focused on how vital life domains (i.e., mental and physical health, family, community, and work) are impacted by CAD, how CAD patients experience the medical and mental health system, CAD patients’ perceptions of the medical healthcare they received, and their recommendations for how medical …

The Psychosocial Factors Influencing Hiv Testing Among Women In Ghana, Janet Okailey Okine

Electronic Theses and Dissertations Archive

HIV testing is still an important component of HIV prevention, and disparities persist among women in Ghana. This study examines psychosocial and socio-demographic factors influencing HIV testing behavior, using data from the 2022 Ghana Demographic and Health Survey. A binary logistic regression result revealed that older, more educated, and wealthier women, and women who utilized HIV test kits, exhibit a much higher likelihood of undergoing HIV testing. Awareness of HIV stigma reduces the likelihood of women undergoing testing. Variations existed depending on the place of residence. Women in rural and northern belts were less likely to undergo testing. Marital status, …

Decorin Promotes Nascent Proteoglycan Retention In Cartilage Matrix By Strengthening Collagen Ii-Aggrecan Integration, Thomas Li, Gabriela Canziani, Yuchen Liu, Neil Patel, Biao Han, Mingyue Fan, Annie Porter, Bryan Kwok, Chao Wang, Qing Li, David E. Birk, Renato V. Iozzo, Irwin M. Chaiken, X. Lucas Lu, Robert L. Mauck, Lin Han

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Cartilage extracellular matrix (ECM), a hydrated collagen II-aggrecan composite, undergoes dynamic turnover during both normal homeostasis and disease-associated remodeling. This study elucidates a crucial role for decorin in promoting the retention and stability of nascent aggrecan within this matrix. By applying bio-orthogonal click-labeling, we demonstrate that loss of decorin accelerates the release of nascent aggrecan under both physiological and inflammatory conditions, without affecting its preferential localization to the pericellular matrix. Conversely, supplementation with exogenous decorin mitigates inflammation-induced loss of nascent aggrecan, supporting its potential as a therapeutic target. At the molecular level, decorin exhibits strong binding affinity for aggrecan, and …

Why Am I Here? Individual, Organizational, & Societal Influences Of Employee Motives To Attend Voluntary Diversity Training And Their Effects On Training Outcomes, Henri T. Maindidze

Dissertations and Theses

Diversity training is a key part of diversity management efforts, but its effectiveness has repeatedly been called into question in both academic and applied spaces, leading many to question its utility. In the case of voluntary diversity training (VDT), where employees can opt in or out of participation, those motivated to attend might not be the ones who would most benefit from participating, thereby limiting the effectiveness of VDT for the organization. As a result, understanding the predictors and outcomes of employee motives to attend VDT can guide improved implementation and evaluation of VDT. Informed by self-determination theory and training …

In Vivo Orf Overexpression Screening Identifies Ccn4 As A Regulator Of Glioblastoma Growth Validated Across Multiple Models, Pushan Dasgupta

Faculty, Staff and Students Publications

Despite current multimodal therapies for glioblastoma (GBM), its prognosis remains grim. Thus, a tremendous need exists to identify new genetic drivers that may serve as potential therapeutic targets in glioblastoma (GBM). We describe an in vivo overexpression screening strategy to identify drivers of glioblastoma where we have leveraged TCGA datasets to conduct a functional genomics screen of prioritized open reading frames (ORFs) that are overexpressed and/or amplified in GBM. To interrogate these potential drivers within a more relevant physiological context, the screening was accomplished in vivo in an orthotopic patient-derived glioma stem-like cell (GSC) model. Among 5 positive "hits" from …

Image Uniformity Evaluation Of Landsat Oli Using Detector Overlap Statistics Of Earth Scenes, Raviv Levy, Cibele Teixeira Pinto, Jeffrey A. Miller, Kurtis Thome

The Characterization and Radiometric Calibration for Remote Sensing Annual Meeting (CALCON)

The Operational Land Imager (OLI) instruments on Landsat 8 and Landsat 9 collect hundreds of Earth scenes per day, covering a wide mix of surface types and signal levels. This report demonstrates that detector overlap statistics can be used to directly characterize non-uniformity at the focalplane boundary zones inherent to the OLI focalplane design and correct for these non-uniformities in image data products. Detector pairs of coregistered pixels within boundary zone represent measurements of the same ground target collected at the same time but with minor view angle differences. The use of multiple pairs of detectors offers varying scene types …

Acute And Inpatient Occupational Therapy Practice For People With Chronic Conditions Who Are Experiencing Homelessness, Emily K. Simpson, Anne K. Mokate, Elizabeth A. Gibbs, Nina K. Duric

Internet Journal of Allied Health Sciences and Practice

Purpose: Despite having high rates of chronic illness, people experiencing homelessness (PEH) in the United States face barriers to healthcare access that result in unmet health needs and poor health outcomes.  The objective of the study was to identify the barriers to service experienced by occupational therapy practitioners (OTPs) in acute and inpatient settings in providing services to PEH and to describe education strategies to reduce those barriers. Methods: Researchers employed a cross-sectional design with OTPs (n=292) with experience treating PEH. Results: Barriers to treatment for OTP included lack of education, need to prioritize acute concerns, and inadequate institutional resources. …

Mutual Mismatch, Diogo M. Santos

Ought: The Journal of Autistic Culture

Mutual Mismatch (2026)

Digital collage

Artist Statement

This collage reflects on the misinformation that frames autism as a unilateral social deficit. Narratives in media, clinical discourse, and scholarship often position neurotypical traits as universal and neutral, while divergent bodies, minds, and ways of being, are frequently interpreted as disorder.

Drawing on the concept of the double empathy problem, as articulated by Damian Milton—the idea that relational breakdown between autistic and non-autistic people is mutual rather than one-sided—this collage questions the assumption that relational complexity originates in autism alone. Instead, the image highlights the differences and complexities that shape both sides. …

Sermon On The Spectrum, Jan A. Wozniak

Ought: The Journal of Autistic Culture

No abstract provided.

"Everyone Leaves Me Behind”: How Harmful Tropes In Fiction Impact Autistic Women, Sara E. Allard

Ought: The Journal of Autistic Culture

Until now, females with ASD have been ignored by healthcare professionals, policymakers, and the general public. The unique presentation of autistic women and girls is now in the cultural spotlight within not just the advocacy and scientific community, but also the arts. Female autistic characters are getting increased representation across literature and television, yet their narratives are still often stuck in the past. Most authors and screenwriters have yet to understand the specific struggles that female autistics face compared to their male counterparts, relying on the outdated, reductive perceptions that have plagued them for decades.

This article outlines three harmful …

Living Through Misinformation: An Autoethnography Of Autism In Chinese Communities, Joy Lu

Ought: The Journal of Autistic Culture

This critical autoethnographic essay examines how misconception, misinformation, and disinformation shape understandings of autism within Chinese communities and produce tangible harm for autistic individuals and their families. Drawing on lived experience, advocacy work, digital observation, and cross-cultural analysis, it explores how language, medical practices, social media, and professional authority sustain persistent misrepresentation.

The essay argues that this misinformation is not merely the result of ignorance, but a socially reinforced and institutionally supported system of knowledge. By situating personal encounters within broader cultural and structural contexts, it highlights the interconnected roles of language, power, and exclusion in shaping autistic lives. It …

Misinformation, Misattunement, And Autistic Theatre: Representation, Access, And Cultural Harm, Sarah J. Nuttall, Jessica Telling

Ought: The Journal of Autistic Culture

This article explores how autistic people experience theatre, showing that exclusion often comes not from individuals but from the way theatre spaces are designed and understood. Using audience feedback from Chameleon (Telling, 2025), an autistic-led production, we look at how common ideas about autism shape both what audiences expect to see on stage and how autistic people are treated in the theatre. Misinformation sets expectations about how autistic people should look, behave, and communicate, and these expectations influence how autistic presence is interpreted. We show how casting autistic performers, designing sensory‑aware environments, and inviting ongoing audience feedback can challenge these …

Pretty Much From Scratch: A Braided Essay On Autistic Diagnosis, Creativity, Identity, And Community, Jenée Stanfield

Ought: The Journal of Autistic Culture

This braided essay uses memoir and research to explore autistic diagnosis, creativity, identity, and community. It examines how the misinformation around these topics harm and “other” autistics: the fallacy of diagnostic objectivity/neutrality, the dual myths of autistic hyper- and hypo-creativity, and autism as an identity defined solely by medical professionals. The memoir sections play with point of view and genre.

Jenée is a late-realized autistic with ADHD and OCD, who identifies as neurodivergent and neuroqueer. She lives in Washington state with her spouse and dog. She has a Master of Fine Arts in Creative Writing and is currently a Master …

Note From The Editors: On Misinformation, Robert Rozema

Ought: The Journal of Autistic Culture

No abstract provided.

Front Matter

Ought: The Journal of Autistic Culture

No abstract provided.

Løp Gård: Revitalyzing History Through Food And Performance, Marija Griniuk, Barbro Laxaa, Magnus Sivertsen Sørvig

DRS Biennial Conference Series

The current research explores the intersection of archives, history, food, and performance. Based on a case study from Løp Gård, a museum site within Nordlandsmuseet in Norway, the museum performance director (museumsregissør in Norwegian) Barbro Laxaa has developed a book that presents historical recipes created by former generations of Løp Gård’s owners. Laxaa explores methods of performing memory and the spirituality of place, positioning food as a catalyst that unites the lived experience of audiences with archival material and historical recipes rooted in the site. The method of this study is artistic research, which has led to the development of …

User-Centered Dread: A Lovecraftian Critique Of Design, Lewis Urquhart, Emma Lawrie

DRS Biennial Conference Series

This paper offers a speculative critique of contemporary design practice through the lens of Lovecraftian horror by critically interrogating assumptions embedded in user-centered design theory. Drawing on the oeuvre of 'weird fiction' author H.P. Lovecraft’s cosmically pessimistic mythologies, this paper explores three thematic dimensions - control, user unknowability, alien materiality - to reveal the limitations of human-centred design paradigms. Utlising examples from literature, film, and everyday experience, this critique demonstrates how design’s aspirational narratives, centered on mastery, empathy, and progress, are increasingly inadequate in addressing the complexities of a more-than-human world. The concept of 'user-centered dread' emerges as a central …

Designing For Transversal Play: Experience, Materiality And Connection, Kim Holflod

DRS Biennial Conference Series

This paper introduces transversal play as a material, experiential, and relational mode of playful inquiry and connection that traverses disciplinary, institutional, and cultural worlds in pedagogy and education. Drawing on design philosophical, posthumanist, and play theoretical perspectives, transversal play is framed as a situated, collaborative, and world-travelling practice of interbeing, where difference becomes a generative site for collective experimentation, care, and transformation. Through four design-based research examples, the paper explores how transversal play emerges in tangible engagements with materials, experiences, and agencies. These examples illustrate how transversal play can reconfigure roles, soften boundaries, and support speculative, caring, and ethical pedagogical …

Scaffolding Transition Pathways: Integrating Ses Resilience As A Dialogic Tool For Community-Based Co-Design, Jiarong Hu, Angus Donald Campbell, Gabriela Baron

DRS Biennial Conference Series

This paper addresses a challenge for Transition Design (TD): how to make long-term, systemic frameworks tangible and actionable in small-scale, community-led practice. We introduce and evaluate the preliminary results of a methodological framework that scaffolds TD backcasting with seven principles of Social-Ecological Systems (SES) resilience for urban gardens. Grounded in a community garden case study in Shanghai, we analyse data from semi-structured interviews and a co-design workshop to evaluate this method in practice. Our findings reveal that this method functions as a dialogic tool, enabling participants to diagnose systemic issues, negotiate trade-offs, and co-create near-term actions with a longer-term vision. …

Ddenso: An Evaluation-Driven Methodology For Information Visualisations, Michele Mauri, Elena Aversa, Anna Cattaneo, María De Los Ángeles Briones Rojas

DRS Biennial Conference Series

When designing Information Visualisations for Media and Information Literacy (MIL) initiatives, a significant challenge lies in ensuring that they effectively transmit and consolidate knowledge, particularly when the Information Visualisation literacy of the audience is unknown. Applying a Research through Design approach, this article describes a meta-process: the reflective and iterative path that led to the definition of DDENSO, a replicable design methodology for creating and evaluating Information Visualisations that allow for knowledge retention. Grounded in prior theoretical and practical experience in Information Design, DDENSO emerged through the development of the artefacts for a MIL exhibition exploring the social implications of …

Value Co-Creation, Co-Displacement, And Co-Destruction In Design: Bridging Value And Values In Human-Data Interaction, Boyeun Lee, Ella Tallyn, Ramprabu Thangaraj, Chris Elsden, Chris Speed

DRS Biennial Conference Series

Data has emerged as a fundamental driver of value creation within design processes, shaping economic, ethical, and environmental outcomes across societies and socio-technical systems. Existing scholarship often frames value in binary terms of co-creation and co-destruction, overlooking the systemic complexities introduced by interconnected, data-intensive systems. This paper introduces the novel concept of value co-displacement to capture how alternative forms of value emerge and displace others within human–data interaction. Drawing on four design research case studies, we investigate how value and values are co-created, co-displaced, and co-destroyed across interconnected, data-intensive systems. We develop a framework that conceptualises the dynamic interplay of …

Emerging Hybrid Human-Genai Workflows To Optimise Human Ideation, Sketching And Design, Mauricio Novoa Munoz, Juan Antonio Islas Munoz, Alejandro Lozano Robledo

DRS Biennial Conference Series

This article presents findings on the reciprocal relationship between industrial design education and the industry it prepares graduates for. Particularly considering the growing impact of Generative Artificial Intelligence (GenAI) on ideation, sketching, design methodologies, and productivity. To inform this research, industry professionals currently integrating GenAI into their practice were consulted to establish benchmarks and highlight critical areas for updated pedagogical approaches and digital transformation, thereby ensuring that design learning and productivity workflows remain relevant. The study arises from an awareness of current workforce shifts that are anticipated to become more pronounced soon. Rapid technological advancements are driving significant cultural and …

Interface Cultures, Forever: Speculative Prototypes For Technological Awareness, Mario Ciaramitaro, Pietro Costa

DRS Biennial Conference Series

As artificial intelligence increasingly takes over the designer’s role in shaping interfaces for services and platforms, a key challenge is how to teach young designers to critically reflect on how design mechanisms shape users and their everyday lives. Interface Cultures, Forever was a design workshop that challenged the conventional notion of the digital interface. Participants were asked to design critical interfaces - concepts that reveal tensions, paradoxes, and invisible mechanisms within digital life. Through speculative and ironic prototypes, students explored how interfaces shape behavior, emotion, and identity. The projects articulate a landscape of cultural critique, where the interface becomes both …

The Memory Loom: Reweaving Curatorial Power Relations With Source Communities In Virtual Reality Cultural Heritage Exhibitions, Ning Zhao, Ziqiang He, Shijie Ming, Haopeng Yuan, Furui Sun, Ke Jiang

DRS Biennial Conference Series

This paper examines how to redistribute curatorial power in VR heritage exhibitions by designing actionable governance mechanisms. We conceptualize VR heritage exhibitions as political curatorial infrastructures rather than neutral storytelling media. We employ a two-stage RtD framework: first building a baseline VR stage, then embedding two mechanisms: Parallel Weave (narrative authorship) and Asynchronous Governance Lock (publishing/veto rights). With N=32 participants, analysis reveals four tensions: (1) community narratives increased affective engagement and epistemic recognition, yet (2) parallel inclusion also risked narrative segregation; (3) a visible veto established accountable workflows, but (4) this power redistribution also transferred sociopolitical risk onto community representatives, …

Designing Motion Identity: Exploring The Aesthetic Expression Of Brand Style Through System Motion, Xinyi Xie, Yinman Guo, Zican Chen

DRS Biennial Conference Series

This study investigates how system motion enhances aesthetic experience and shapes users’ interpretation of brand style. Using Windows 11, macOS, and HarmonyOS as representative cases, the study analyses four categories of system animations through a motor-level framework comprising temporal, spatial, and transformational attributes. Twelve motion samples were coded, and participants evaluated each sample using perceptual adjectives. The results show that consistent attribute patterns across functional categories lead to stable aesthetic tendencies, while differences emerge from how each system repeatedly applies these attributes. These attribute biases create distinct perceptual profiles, indicating that motion can function as a subtle medium for expressing …

No One Knew. They Came. Exploring Photo-Elicitation In Societal Development, Jennie Schaeffer, Mira Karlsson, Andreea Strineholm, Erika Andersson

DRS Biennial Conference Series

Citizen dialogues strive for inclusivity but often exclude marginalized groups. New participatory and creativity-based approaches are needed to be evaluated and become a part of the skillset repertoire for public officials to foster an inclusive dialogue. This paper reflects on photo-based conversations as a dialogic method for societal development and inclusion. The results show that the method provides possibilities to creatively involve participants, strengthen relationships and open a space for diverse narratives between different actors in society. However, the challenges of internal exclusion, lack of strategies for impact, and the need to build competence in handling conflicting stories, without depoliticizing …

Interiority As A Pedagogical Approach In Interior Design Studio Education, Selin Aktan Abraham, Fulya Özbey

DRS Biennial Conference Series

As the central platform of design education, interior design studios function as dynamic learning environments that advance creativity and sensitivity to the social and spatial dimensions of design. Although the experiential qualities of space are conceptually acknowledged within studio pedagogy, the notion of ‘interiority’ remains unstudied compared to the emphasis placed on technical requirements. This paper positions interiority as a critical yet underexplored component of interior design pedagogy. Through a literature mapping and thematic synthesis, this paper defines five core dimensions of interiority as (1) spatial, (2) sensory, (3) affective, (4) identity-related, and (5) temporal, then correlates these dimensions in …

Interspecies: A Collaborative Curatorial Inquiry Into New Romanticism, Mariana Pestana, Katerina Inglezaki, Carlos Pastor, Mathilde Gouin, Bernardo Gaeiras, Fernanda Costa, Mariana Simões

DRS Biennial Conference Series

This paper presents a situated, plural, and horizontal curatorial methodology centered on questioning rather than providing solutions in response to posthuman thought and practice. It inquires whether we might be witnessing the emergence of a New Romanticism in contemporary design and architecture concerned with interspecies relations. This romantic turn arises by acknowledging subjectivity and imagination while engaging critically with the complexities of the climate crisis. To this end, this paper examines the making of an exhibition that assembled material evidence from science, art, technology, and design. The exhibition was developed through a three-step curatorial framework aligned with the decentering narratives …

Enframing Creativity: Speculations On Design Education's Transformations In The Age Of Generative Ai, Alireza Sharifi, Michael Hohl, Fredrik Skatar

DRS Biennial Conference Series

The rapid advancement of AI technologies necessitates a shift from reactive adoption to speculative inquiry into long-term consequences for educational systems. Grounded in Martin Heidegger's "The Question Concerning Technology," this research examines the epistemology of AI in design education. Methodologically, it employs speculative futurology, integrating speculative design, critical design, and scenario planning to explore possible futures, culminating in a philosophical mapping framework based on Heidegger's critical stance. The findings reveal a critical temporal mismatch between rapid AI capability growth and slower educational adaptation, creating urgency for human-centered frameworks. The research concludes that design education's future depends on consciously cultivating Critical …

The Lustre Of Hands, Ziyan Wang

DRS Biennial Conference Series

This paper introduces the lustre of hands—a term used to describe the gentle, subtle sheen that appears on things through long and caring contact with human hands. This concept challenges the visual paradigm and the pursuit of the new in contemporary design. It suggests that the traces of touch and time embody care, continuity, and human presence. Illustrated through the author’s example of a family inkstone, whose surface bears the lustre accumulated over generations, it offers design a powerful perspective: to appreciate the marks left by time and use to make things more fully used rather than wasted; to give …