Digital Commons Network^™

Modifying The L-Tryptophan Affinity Of The Ribosomal Arrest Peptide Tnac, Alexis Orlando Delgado Castillo

Theses

Since creating biosensors from zero has proven a more challenging enterprise than expected, resorting into naturally occurring regulatory systems already characterized represents a more accurate, rapid, and attractive option. Various previous strategies have sought to exploit and modify regulatory elements that sense for different molecules, including monosaccharides (Tang et al., 2008), secondary metabolites (Flachbart et al., 2021), and other amino acids (Della Corte et al., 2020). This study aims to leverage current scientific knowledge and advances concerning the structure and function of the ribosomal arrest peptide TnaC. With this research I integrated the TnaC ribosome-arresting peptide into a new biosensor …

Improving Satellite Needs Working Group Assessment Process Through Automation And Process Consolidation, Raj Dangol

Theses

The increasing complexity of modern software ecosystems, presents significant challenges to system resilience, maintainability and automation. This work presents a proof-of-concept implementation of an automation system to address these challenges for a large scale fragmented software systems. Succinctly we address these challenges in the context of Satellite Needs Working Group (SNWG), which is responsible for collecting and communicating federal agencies' Earth observation needs to National Aeronautics and Space Administration (NASA). Multiple automation scripts and applications exist to support the SNWG's assessment cycle, encompassing the areas of data validation, visualization, report generation, and user management. However, the dispersion of these tools …

2024 - 2025 Faculty Senate Annual Report, University Of South Carolina

Faculty Senate

The primary file includes the 2024 - 2025 Admissions Committee Report. Additional annual reports are attached.

Comparing Funders' Altruism Versus Self-Interest: Leveraging The Context Of Crisis, Dan Liu, Guangzhi Shang, Cynthia Fan Yang

Journal of International Technology and Information Management

While reward-based crowdfunding has widespread popularity, the motivations driving funders, balancing self-interest and altruism, have remained puzzling. Prior research has been constrained by examination methods and produced mixed findings regarding the weight of altruism versus self-interest among funders. Our study takes a fresh perspective, delving into funder behavior amid a major crisis—the tumultuous backdrop of the COVID-19 pandemic. Our findings reveal that funders not only display an increased willingness to contribute but also significantly amplify their contributions, particularly to projects in crisis-affected regions, irrespective of external incentives like rewards. This underscores the prevalence of altruistic motives among funders in challenging …

Understanding The Determinants Of Blockchain Adoption: An Empirical Study, Amarpreet Kohli, Nihar Kumthekar, Piyush Shah, Rebecca Jauch

Journal of International Technology and Information Management

Blockchain technology (BT) has the potential to enhance security and robustness of transactions through a distributed ledger bookkeeping process. This study employs technology-organization-environment (TOE) framework and threat-rigidity theory (TRT) to examine whether perceived disruption caused by COVID-19 pandemic significantly impacted the adoption of BT, and inclination to adopt BT in the US. The COVID-19 pandemic provided a unique backdrop, as it affected businesses across all industries, sizes, and geographies. Results show a non-significant effect of perceived pandemic disruption on the current stage of BT adoption and intention to adopt BT. However, disruption readiness positively influences the current stage of BT …

Comparing Vr And Tv In Nigeria And The U.S.: Impacts On Empathy, Engagement, And Enjoyment, Jinhee Yoo, Eugene A. Ohu, Radosław Mącik

Journal of International Technology and Information Management

This study (N = 170), involving participants from Nigeria and the U.S., investigated how different technologies (TV and VR) affect users' empathy (α = .93), engagement (α = .93), enjoyment (α = .93), preferences, and likelihood of technology use. Participants watched an animated documentary titled “Is Anna OK?” at two different time points, utilizing VR (Oculus Rift S) and TV, following which they completed measuring empathy, engagement, enjoyment, device preference, and usage likelihood. Analysis via one-way ANOVA and chi-square tests revealed that VR users reported significantly higher empathy and enjoyment compared to TV viewers, particularly on second viewing. Combining both …

Latine Students In U.S. Schools: An Interactive Resource Book For Educators, Melissa Colón

OER Textbooks

This interactive resource book provides educators with highly curated research, academic scholarship, and community-based materials to better inform and support their work with Latine students, families, and communities. Grounded in critical and culturally sustaining pedagogies (Rendón et al., 2014; Alim & Paris, 2017). This book encourages educators to cultivate a spirit of curiosity, collaboration, and continuous learning, recognizing that serving Latine students well requires both commitment and ongoing inquiry.

Characterization Of Litigation After Tympanoplasty And Mastoidectomy In The United States, Alyssa D. Reese, Lauren A. Dinardo, Soumya Gupta, Kristina F. Powers, Samuel Colca, Michele M. Carr

Department of Otolaryngology (ENT) Faculty Publications

Introduction

Tympanoplasty and mastoidectomy are common procedures performed by otolaryngologists that can result in complications for which patients may seek compensation. Medical malpractice case analyses may offer insight into how clinicians can avoid risk and improve patient satisfaction. We aimed to comprehensively characterize litigation after mastoidectomies and tympanoplasties in the United States.

Methods

The Westlaw Campus Research legal database was searched for all available court decisions associated with claims of medical malpractice after tympanoplasty and/or mastoidectomy in the United States between 1975 and 2022. Information on the plaintiffs' relationships to the patients, patient characteristics, states where the procedures took place, …

Otolaryngology Applicants' Preferences For Virtual Vs. In-Person Interviews During The 2023-2024 Application Cycle, Taylor S. Erickson, Robert Frederick, Steven D. Pletcher, Aileen Dowden, Dana Dunleavy, Eric J. Dobratz

Department of Otolaryngology (ENT) Faculty Publications

Background Since the shift to virtual residency interviews, applicants and programs have reported difficulty distinguishing themselves in a virtual format, reduced exposure to medical campuses, and limited opportunity to establish personal connections. The 2023-2024 application cycle was the first time virtual and in-person interview formats were available in otolaryngology–head and neck surgery (OHNS). Programs offered one or both formats, and in some cases, applicants were given the choice between the 2.

Objective To assess the perceptions of OHNS applicants regarding virtual versus in-person interviews during the 2023-2024 application cycle.

Methods A 20-question survey was distributed via email through the Association …

Angelilli V. Activision Blizzard, Northern District Of Illinois

Historical and Topical Legal Documents

No abstract provided.

Us V. Mcgee, Southern District Of Alabama

Historical and Topical Legal Documents

No abstract provided.

Ed Lee Discern Magazine Fall 2025, Ed Lee

Historical and Topical Legal Documents

No abstract provided.

United States V. Terranova, Eastern District Of New York

Historical and Topical Legal Documents

No abstract provided.

Describing And Understanding The Use Of Coaches For Eating Disorder Recovery: A Mixed Methods Study, Taylor E. Penwell

Graduate Student Theses, Dissertations, & Professional Papers

Individuals with eating disorders (EDs) experience high rates of relapse and delays in accessing treatment. Considering these factors, individuals with EDs may seek out non-traditional support, such as coaching services (e.g., an unlicensed individual providing support). However, there is currently no research on individuals with EDs’ experiences with using coaching services for ED recovery. The current study aimed to a) describe who is utilizing coaching support, b) describe coaching services received, c) evaluate the motivations for seeking coach support, and d) evaluate the perceived impact of coach support on an individual’s ED recovery. Participants included 86 adults with a self-reported …

Precision Public Health Alliances As A Model And Method For Community Engagement, Margaret L. Mcgladrey, Mary Elizabeth Lacy, Kristen Mcquerry, Rachel Hogg-Graham, Svetla Slavova, Emily R. Clear, Kory Heier, Caitline Phan, Megan Hall, Ryan Parker, Mindy Keeton, Jennifer Sword, Thomas Ard, Charbel Salem

Epidemiology and Environmental Health Faculty Publications

Using precision analytics approaches with population health data helps identify localized patterns of social determinants and comorbidities, supporting the design of tailored interventions. The University of Kentucky College of Public Health (UKCPH) and UK King’s Daughters (UKKD) have partnered to create a Precision Public Health Alliance (PPHA) applying precision analytics to UKKD electronic health records (EHR) as well as secondary datasets to map social, demographic, and clinical comorbidity factors onto colorectal cancer (CRC) screening data in UKKD’s rural service area (the northeastern Kentucky counties of Boyd, Carter, Greenup, and Lawrence and southeast Ohio county of Lawrence). In addition to UKKD …

Education About, In, And For Wetlands: Practices, Premises, Possibilities, And Challenges, Tom Marcinkowski

Mathematics and System Engineering Faculty Publications

The purpose of this paper is to review areas of educational theory, research, and practice relevant to wetlands education, notably education about, in, and for wetlands. Five key areas are reviewed: (a) from the Report of the Intergovernmental Conference on Environmental Education, goals and objectives for wetlands education; (b) from the literature, major curricular and instructional approaches in and elements of wetlands education; (c) from the literature, broad instructional strategies available to and commonly used in wetlands education; (d) from websites of federal agencies in the U.S., education, outreach, and training programs that focus on education about, in, and for …

Ground-Based Cloud Type Classification For Aviation Weather Hazard Detection Using Deep Learning, Marcus P. Cote, Michael E. Splitt, Steven M. Lazarus, Ryan T. White, Cecilia G. Baker

Mathematics and System Engineering Faculty Publications

General aviation pilots who encounter hazardous weather face a heightened risk of fatal accidents compared to those in other sectors of aviation. To help avoid unplanned weather encounters, accurate information on cloud type and sky conditions can enhance situational awareness and hazard recognition. Among available weather information resources, ground-based webcam networks are growing for aviation meteorology and other interests such as wildfire monitoring. These webcams can provide near-real-time visual weather information to pilots, especially in regions of complex terrain where traditional weather observation methods may lack adequate spatial and temporal coverage. To harness the benefits from webcams while reducing the …

Reproductive Health Education In Ghana: Perspectives Of School Health Education Programme (Shep) Coordinators, Population Council, Msi Reproductive Choices, Ghana Education Service, Ghana Health Service

Sexual and Reproductive Health, Rights, and Choices

Schools in Ghana have integrated reproductive health education (RHE) topics into their curricula and School Health Education Programme (SHEP) Coordinators recognize the importance of RHE. However, for RHE to reach its full potential, it needs to be established as a stand-alone subject. This study highlights the challenges and opportunities in delivering in-school RHE, underscoring the interplay between policy frameworks, implementation strategies, and locally accepted approaches.

A Series Of Studies On Social Annotation: How They Came To Be, Virginia Clinton-Lisell

Education, Health & Behavior Studies Faculty Publications

No abstract provided.

Potentiation Of Gelonin Cytotoxicity By Pulsed Electric Fields, Olga N. Pakhomova, Eleni Zivla, Giedre Silkuniene, Mantas Silkunas, Andrei G. Pakhomov

Bioelectrics Publications

Gelonin is a ribosome-inactivating protein with extreme intracellular toxicity but poor permeation into cells. Targeted disruption of cell membranes to facilitate gelonin entry is explored for cancer and tissue ablation. We demonstrate a hundreds- to thousands-fold enhancement of gelonin cytotoxicity by pulsed electric fields in the T24, U-87, and CT26 cell lines. The effective gelonin concentration to kill 50% of cells (EC₅₀) after electroporation ranged from <1 nM to about 100 nM. For intact cells, the EC₅₀ was unattainable even at the highest gelonin concentration of 1000 nM, which reduced cell survival by only 5–15%. For isoeffective electroporation treatments using 300 ns, 9 µs, and 100 µs pulses, longer pulses were more efficient at lowering gelonin EC₅₀. Increasing the electric field strength of 8, 100 µs pulses from 0.65 to 1.25 kV/cm reduced gelonin EC₅₀ from 128 nM to 0.72 nM. Conversely, the presence of 100 nM gelonin enabled a more than 20-fold reduction in the number of pulses required for equivalent cell killing. Pulsed electric field-mediated delivery of gelonin shows promise for hyperplasia ablation at concentrations sufficiently low to minimize or avoid systemic toxicity.

The Effect Of Liquid Conductivity On A Helium Plasma Jet And The Hydrogen Peroxide Production, Edwin A. Oshin, M. Ziaur Rahman, Chunqi Jiang

Bioelectrics Publications

Understanding plasma-liquid interactions and the impact of the electrical conductivity (σ) of liquid on plasma is important for plasma applications in water treatment and medicine. Ultrapure water, phosphate-buffered saline (PBS) solution, biological media, and sodium chloride (NaCl) solutions at various concentrations were used in this study to provide a broad range of conductivity values ranging from 0.055 μS cm⁻¹ to 222 mS cm⁻¹. A helium atmospheric pressure plasma jet (APPJ) impinging on liquid was generated in ambient air using a hollow-needle electrode that was powered by 200 ns, 7 kV pulses at a pulse repetition frequency of …

Place-Based Learning Practices: A Diptych Case Study Of Human And More-Than-Human Relationality At The Tribal And Western Academic Institutional Interface, Karley M. Rojas-Vienneau

Cal Poly Humboldt theses and projects

The ‘Place-Based Learning Practices Project’ is a graduate project under the Native American Studies Department Rou Dalagurr Food Sovereignty Lab and Traditional Ecological Knowledges Institute (FSL). Making contributions at the intersection of Western academia and Indigenous science, it imagines and realizes content, policies, and protocols surrounding two case studies and the larger cal poly humboldt (cph) institution which respect, honor, and uplift Indigenous sovereignty and resurgence in partnership with the Blue Lake Rancheria Tribe and the greater regional tribal community. Encompassing two projects internal and external to the institution, I aim to address the construction of controlled and protective environments …

Grade-Band Instructional Framework Using Art Integration As A Social Emotional Learning Tool To Increase Accessibility And Equity For All Learners, Greta Dodson Turney

Cal Poly Humboldt theses and projects

Based on my experiences in education, I endeavored to develop a sustainable grade-band instructional curriculum integrating art as a low-floor, high-ceiling, social-emotional learning tool to increase accessibility and equity for all learners while addressing the need for social interaction to abate the increase in violence, mental health issues, and the feelings many students have that they are unworthy of success. To achieve this framework and promote sustainability, I mapped the curriculum currently available at a rural California school district, identified techniques for teaching three or more grades in one classroom, and I designed a program to cover all standards through …

Brokered Violence: Safety For Sale In The Free Marketplace Of Data, Sam Adler, Thomas E. Kadri, Chinmayi Sharma

Popular Media

This article exposes how the unregulated data broker industry fuels violence by selling detailed personal information gathered from public records, social media, and private sources. Drawing on the Minnesota assassinations and other cases, it shows how such data enables stalking, harassment, and targeted attacks. The piece critiques state and federal laws like California’s DELETE Act and New Jersey’s Daniel’s Law for leaving victims to navigate slow, fragmented removal processes. It proposes a centralized victim registry with rapid compliance requirements, shifting responsibility to brokers. Finally, it challenges the industry’s First Amendment defense, urging legal reforms that prioritize public safety over commercial …

Wellness And The Tax Law, Leigh Z. Osofsky

Georgia Law Review

The tax law has long provided extensive subsidies for “medical care.” These subsidies cost the government hundreds of billions of dollars a year. The definition of medical care, which is at the heart of these subsidies, originated many decades ago at a time when there was little to no conception of wellness.

Times have changed in the medical world. Medical science now emphasizes that wellness practices, like exercise, meditation, and social connection, have an important impact on physical as well as mental health, including by playing a significant role in preventing and treating disease. Under the tax statute, medical care …

The Grey Market’S Ability To Be Black And White: Regulating For Fraud In Online Marketplaces Beyond The Inform Consumers Act, Jack A. Cofer

Georgia Law Review

The rapid expansion of e-commerce and the rise of secondary online marketplaces, amplified by the COVID-19 pandemic, have fundamentally altered consumer shopping behaviors. These marketplaces entice online shoppers with appealing benefits, such as sustainability, wallet-friendly pre-owned selections, or by simply offering what no one else can—accessibility. However, as demand for coveted goods outpaces supply, grey-market transactions flourish, exposing consumers to a risk of counterfeit and illicit products.

This Note examines the INFORM Consumers Act, a regulatory framework aimed at enhancing transparency within secondary online marketplaces by imposing disclosure requirements on certain third-party sellers. While the Act represents a significant step …

Federalizing Ncii Regulation: The Take It Down Act’S Approach To Criminalization, Platform Liability, And Threats To Disseminate, Trudi K. Sundberg

Georgia Law Review

For years, legal scholars, advocates, and victims have pushed for the federal criminalization of the nonconsensual publication of intimate imagery. Until now, regulation has been inconsistent across jurisdictions, often leaving victims without meaningful remedies or mechanisms for image removal.

The recent passage of the Take It Down Act has finally realized the goal of federal criminalization of nonconsensual intimate image distribution, including that of artificially generated images. The Act further initiates a framework for victim-led takedown procedures and engages with § 230 liability. Additionally, the Act addresses threats to disseminate such content, which is crucial to curb the spread of …

“That Middle School Is Trash!!!!”: Public Knowledge About Local Schools On Social Media, Ashley Carey

Education Faculty Publications

Purpose: Americans frequently turn to online social networking sites (OSNs) as a source of news and information. Yet the role of OSNs in knowledge formation about local public schools remains underexamined. This study explores how public knowledge about local schools is constructed on Facebook. Research Methods/Approach: This ethnographic case study centers on a large “private” Facebook group in the community of Oldtown (pseudonym). Drawing on digital public sphere theory, this study examines who posts about the schools on Facebook, what they post, and how interaction shapes the collective knowledge about local schools on Facebook and beyond. Findings: Posts with the …

Kittens, Community, Kids, And Classrooms: Exploring And Embracing Empathy, Maureen F. Ruby

Education Faculty Publications

No abstract provided.

Csbs Statements, V26, 2025, University Of Northern Iowa. College Of Social And Behavioral Sciences.

CSBS Statements

Contents:

From the Dean --- 3
Shaping Tomorrow --- 4
Helping Students Cross the Finish Line --- 10
Beyond the Uniform --- 12
Finding the Right Fit --- 14
From Patient to Colleague --- 16
Diplomacy in Action --- 18
College News --- 20
Panther Spotlights --- 24
Annual Giving --- 26
Class Notes --- 39