Digital Commons Network^™

Novel Flavonoid Derivatives Show Potent Efficacy In Human Lymphoma Models., Eugenio Gaudio, Paulina Biniecka, Alberto J Arribas, Eleonora Cannas, Guido J R Zaman, Derya Unutmaz, Francesco Bertoni, Dan F Stoicescu

Faculty Research 2025

BACKGROUND: Despite significant therapeutic progress, many lymphoma subtypes remain difficult to manage due to resistance, relapse, and dose-limiting toxicity.

METHODS: To elucidate the mechanism of action of the semi-synthetic flavonoid derivative (SND) compounds, we conducted a screening of cancer cell lines using proliferation, cell cycle, and apoptosis assays. We then performed computational modeling of the compounds' binding to tubulin, and finally evaluated in vivo activity using nanoNail technology alongside xenograft experiment.

RESULTS: Here, we describe a series of SNDs that exhibit low-nanomolar to picomolar cytotoxicity across multiple lymphoma models, including those resistant to BTK and PI3K inhibitors. Mechanistic studies show …

"Maine Office Of Behavioral Health’S Section 17 Self-Direction Pilot Program: Executive Summary", Rachel M. Gallo Mph, Sarah Goan, Emma Schwartz

Publications

The Self-Directed Care (SDC) pilot program in Maine tested a service delivery model that allows individuals with mental health needs to manage a personal budget, supported by a trained broker to purchase goods and services that best support their recovery goals. Funded through the American Rescue Plan Act, the Maine Office of Behavioral Health implemented the nine-month pilot in three counties, partnering with Alpha One, Maine’s Center for Independent Living, to provide reloadable debit cards for participant purchases. The program aimed to promote autonomy, satisfaction, and stability among adults receiving Section 17 Medicaid services while informing decisions about the model’s …

Summary Of: Lessons Learned: Enhancing Rural Risk Communication For Future Health Crises Through The Phercc Framework, Abimbola Leslie, Elizabeth K. Woods, Eline M. Van Den Broek-Altenburg, Jan K. Carney

Northern New England Clinical & Translational Research

This study shows the importance of evidence-based, adaptive, and population subgroup sensitive communication during public health emergencies. The PHERCC framework provided a useful structure for identifying barriers, building trust, and guiding responsive strategies. Investing in inclusive communication systems and leveraging community partnerships are important for effective responses to future health crises.

Study found @ Lessons learned: enhancing rural risk communication for future health crises through the PHERCC framework

Discovery Of Alcohol Dehydrogenase (Adh) As A Potential Vaccine Target From Mycolicibacterium Smegmatis Extracellular Vesicles Via Immunoproteomics, M. Jayaram, N. Othman, Khayriyyah Mohd Hanafiah, M. Azlan, N. Arifin

Biology Faculty/Staff Publications

Mycobacterium tuberculosis (MTB), the causative agent of tuberculosis, releases extracellular vesicles (EVs) that impair macrophage functions and circulate bacterial components to modulate the host immune response. While EVs are increasingly investigated as new vaccines and biomarkers, studying MTB EVs is challenging due to the slow growth rate and pathogenic properties of MTB. Mycolicibacterium smegmatis (MSMEG), a non-pathogenic surrogate with a faster growth rate, offers a safer and more convenient option for laboratory studies due to its similarities to MTB. In this study, we explore the antigenic properties of MSMEG EVs to assess their potential use in developing safer tuberculosis vaccine …

The Tomb Of Louis Of Mâle And The Materiality Of Brass In The Burgundian Netherlands, Douglas Brine

Art and Art History Faculty Research

The brass and stone tomb of Louis of Mâle and Margaret of Brabant, Count and Countess of Flanders, and their daughter Margaret, Duchess of Burgundy, formerly in St. Peter’s Church, Lille, is long destroyed but had a pivotal role in the history of Burgundian funerary sculpture. It was commissioned in 1453 by Louis’s great-grandson Philip the Good, Duke of Burgundy, although it was Duchess Isabella of Portugal who actually negotiated its contract with the Brussels brass founder Jacob van Gerines. Close examination of the circumstances of the tomb’s creation, notably Philip’s recent suppression of the Ghent revolt, illuminate the interrelation …

A Research Guide And Annotated Bibliography For The Comparative Study Of Lgbtqia+ Social Movements Across East Asia, San Lee

FIRE Fund Bibliographies

This bibliography includes literature on how LGBTQIA+ movements across East Asia have evolved through local histories, politics, and cultural understandings of sexuality. While many societies had pre-existing, non-Western concepts of same-sex relations, post-1990s democratization and global human rights discourse reshaped activism in distinct ways. Movements in places like the People’s Republic of China, the Republic of China (Taiwan), South Korea, Japan, and Hong Kong engage with nationalism, decolonial perspectives, and social norms to construct unique approaches to queer rights. The guide highlights the need to understand LGBTQIA+ activism through each society’s specific historical and political context.

Empowering Community Voices, Kyle Morgan

Cal Poly Humboldt Library

No abstract provided.

Guidelines For Energy Technology Demonstrations, Ian M. Shapiro

SyracuseCoE

This document is intended to provide guidance to companies developing new products, researchers, organizations sponsoring product development, demonstration hosts, resident organizations, and policymakers. The guidelines were prepared to maximize the chances for success of energy technology field demonstrations. Guidance is provided for effective site recruitment, project scoping and design, installation, onsite research, and related work such as public communication and risk management, all in ways that fully engage demonstration hosts.

Political Sociology, Talha C. Issevenler

Open Educational Resources

This open-access textbook on political sociology introduces and problematizes the classical categories and parameters of the field. It explores the main approaches to the state and governance, while conceptualizing a turn toward network power. Specific chapters address political spacetime, violence, secrecy, social movements, politicization, interdisciplinarity, media, biopolitics, and event-analysis. Multimedia pedagogical exercises accompany the conceptual exposition.

Why Medicaid Is Addressing Homelessness With Section 1115 Waivers: A Critical Examination Of The United States' Federalist Mental Health System, Joshua Haas

Washington Law Review

Housing and health care are deeply interconnected, and their systemic relationship profoundly affects individual and societal well-being. Inadequate funding has undermined the American mental health system for decades, leading to gaps in care that have caused lasting harm to vulnerable individuals and society as a whole. This Comment examines the historical connections between homelessness and the American mental health system. It explores the benefits and criticisms of the United States’ federalist approach to health care, particularly focusing on Medicaid and its “section 1115 waivers,” which grant states flexibility to develop innovative, state-specific Medicaid programs. Recently, states began to utilize section …

The Virgin Of Guadalupe And The Liminality Of Pregnancy, Jason Oosting

Theses

This thesis suggests that the image of the Virgin of Guadalupe, during the Colonial Period, provided the diverse population of colonial New Spain (and, in particular, Mexico City/Tenochtitlán) with an image that functioned to unify even some of the most seemingly disparate belief systems, those of Christian Spaniards and Indigenous Nahuatl traditions. More specifically, this thesis argues that this unification was achieved because the image of the Virgin of Guadalupe in the 16th and 17th centuries was likely understood as representing a divine pregnant woman to many colonial viewers—a state that bound viewers, both Spanish and Indigenous alike, to shared …

Review Of The Medici Curse, Michael F. Russo

Faculty Publications

No abstract provided.

Submittal Of Mixed Waste Landfill Annual Long-Term Monitoring & Maintenance Report, April 2024-March 2025 For Sandia National Laboratories/New Mexico, Epa Id Number Nm5890110518, June 2025, Sandia National Laboratories/Nm

Facilities-Units

The Department of Energy/National Nuclear Security Administration (DOE/NNSA) and Sandia National Laboratories /New Mexico (SNL/NM) personnel submitted the Mixed Waste Landfill (MWL) Annual Long-Term Monitoring and Maintenance Report for the April 2024 through March 2025 reporting period to the New Mexico Environment Department (NMED) in accordance with the requirements of Section 4.8.1 of the MWL Long-Term Monitoring and Maintenance Plan (LTMMP). The LTMMP became effective on January 8, 2014.

The MWL is a 2.6-acre Solid Waste Management Unit (SWMU 76) located in the north-central part of Technical Area III at SNL/NM that has undergone corrective action. As of March 13, …

Culturally Responsive Intimate Partner Violence (Ipv) Service Needs Among African Immigrant Women: Examining The Impact Of Cultural Norms And Psychosocial Barriers On Safety Perceptions And Help-Seeking Behaviors, Titilayo Ogunbambi

Dissertations

Intimate Partner Violence (IPV) remains a pervasive public health and social justice issue globally, with African immigrant women in the United States facing compounded challenges as they navigate cultural, structural, and systemic barriers, including migration-related vulnerabilities and attachment to cultural values that shape their decisions and experiences. Although formal IPV services exist, they often fail to address the lived realities and culturally specific needs of this population, leading to underutilization and barriers in seeking help. This qualitative study examines how cultural norms, psychosocial barriers, and systemic inequities influence safety perceptions and help-seeking behaviors among African immigrant women survivors of IPV. …

Front Matter

Swiss American Historical Society Review

No abstract provided.

The Epidemiology And Burden Of Injury In Countries Of The Association Of Southeast Asian Nations (Asean), 1990–2021: Findings From The Global Burden Of Disease Study 2021, Stephanie C C Van Der Lube, Lin Siew Chong, Simon I. Hay, Catherine Bisignano, Spencer I. James, Xiaochen Dai, Lay Hoon Goh, Swetha Acharya, Qorinah Estiningtyas Sakilah Adnani, Naveed Ahmed, Budi Aji, Joseph Uy Almazan, Carl Abelardo T. Antonio, Sumadi Lukman Anwar, Muhammad Shahzad Aslam, Atif Amin Baig, Amiel Nazer C. Bermudez, Ahmad Naoras Naoras Bitar, Muthia Cenderadewi, Hana Chen, Nicholas Ws Chew, Bryan Chong, Mayank Dalakoti, Hisham Atan Edinur, Crystal Amiel M. Estrada, Emerito Jose Aquino Faraon, Nelsensius Klau Fauk, Ni Kadek Yuni Fridayani, Fernando Barroga Garcia, Arief Hargono, Eka Mishbahatul Marah Has, Paul Michael Rafa Hernandez, Nahlah Elkudssiah Ismail, Vikash Jaiswal, Roland Dominic G. Jamora, Jost B. Jonas, Kehinde Kazeem Kanmodi, Inn Kynn Khaing, Yun Jin Kim, Chong-Han Kua, Maria Dyah Kurniasari, Dian Kusuma, Hilton Lam, Shaun Wen Huey Lee, Zheng Feei Ma, Roy Rillera Marzo, Kamarul Imran Musa, Firzan Nainu, Dina Nur Anggraini Ningrum, Sok King Ong, Veincent Christian Pepito, Thantrira Porntaveetus, Dimas Ria Angga Pribadi, Sheena Ramazanu, Bedanta Roy, Yoseph Leonardo Samodra, Siddharthan Selvaraj, Shazlin Shaharudin, Robert Sinto, Solikhah Solikhah, Chandrashekhar T. Sreeramareddy, Vetriselvan Subramaniyan, Thitiporn Sukaew, Ingan Ukur Tarigan, Jansje Henny Vera Ticoalu, Narayanaswamy Venketasubramanian, Taweewat Wiangkham, Anggi Lukman Wicaksana, Siyan Yi, Mustafa Z. Younis, Christopher J L Murray, Kanyin Liane Ong, Yee Wei Lim, Marie Ng

Ateneo School of Medicine and Public Health Publications

Background Injuries are among the top causes of mortality and disability in southeast Asia. Although injury prevention is a key health priority in the Post-2015 Health Development Agenda of the Association of Southeast Asian Nations (ASEAN), the focus was placed solely on road injuries. The absence of a broader recognition of injury burden and trends hinders future intervention efforts. This study aims to provide a comprehensive analysis of the burden and epidemiological trends of all injuries across ASEAN countries.

Methods In this analysis of the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2021, we estimated incidence, cause-specific …

"Maine Office Of Behavioral Health’S Section 17 Self-Direction Pilot Program: Evaluation Report", Rachel M. Gallo Mph, Sarah Goan, Emma Schwartz, Aaron Rose

Publications

Maine’s Office of Behavioral Health conducted a nine-month pilot of Self-Directed Care to support adults with serious mental illness in Cumberland, Hancock, and Washington Counties. The program allowed eligible participants receiving MaineCare Section 17 services to manage a personal budget, guided by trained Support Brokers from Alpha One, to purchase goods and services that would advance their recovery goals. The pilot aimed to increase participant choice, autonomy, and flexibility in managing their mental health needs. Support Brokers worked closely with participants and Case Managers to develop and approve individualized purchase plans, monitor expenditures, and ensure alignment with treatment objectives. A …

The Glass Menagerie, Otterbein Theatre And Dance Department

2025 Summer Theatre

No abstract provided.

Decommissioning Offshore Oil And Gas Infrastructure: Report Of Proceedings, May 2, 2025 Offshore Decommissioning Workshop, Martin Lockman, Ashwin Murthy, Romany M. Webb

Sabin Center for Climate Change Law

On May 2, 2025, Ocean Conservancy and the Sabin Center for Climate Change Law organized a workshop at Columbia Law School on offshore oil and gas decommissioning in the United States. The overarching goal of the workshop was to bring together offshore law and policy experts to outline a research and policy agenda for offshore decommissioning. Within this broad goal, we sought to (1) identify key opportunities to reform offshore decommissioning law in the United States, both in the short term and over the next decade, (2) identify knowledge gaps and highlight areas for future research, and (3) begin to …

Opposition To Renewable Energy Facilities In The United States: June 2025 Edition, Matthew Eisenson, Jacob Elkin, Ivonne Norman, Rebecca Coombs, Chadol Kim, Rex Koenig, Suzan Michalski, Eric Quiroz, Josepi Scariano, Ava Teasdale, Victor Tong, Annabel Williams

Sabin Center for Climate Change Law

Increasing the amount of electricity generated in the United States to power electric vehicles, data centers, and other end uses, while simultaneously reducing greenhouse gas emissions will require deploying a massive number of renewable energy facilities at an unprecedented scale and pace. Although many renewable energy facilities are sited without a problem, local opposition often arises. The Sabin Center’s annual report, Opposition to Renewable Energy Facilities in the United States, documents legal obstacles and challenges that arise during the siting process. In particular, the report focuses on: (a) state laws and local ordinances (“restrictions”) that impede the siting and deployment …

"Great Big Beautiful Tomorrow": Disneyland, Science, And The Cultural Cold War, Emily Searson

Master's Theses

Disneyland, the popular Anaheim-based theme park in California, opened its doors during heightened Cold War tensions in 1955. In this thesis, I trace the origins of Tomorrowland, one of the five original themed lands in Disneyland that included futuristic rides and attractions to depict Walt Disney’s imagining of the year 1986. I examine Tomorrowland in particular to argue that WED Enterprises (Disneyland, Inc.’s research and development arm) and Disney’s vision of scientific progress aligned with U.S. Cold War policy goals, especially containment. Disney and WED Enterprises meticulously planned Tomorrowland with the help of notable American defense contractors, including the Monsanto …

New Sheriff In Town: A Quad Model Approach To Examining The Consequences Of Selecting A Qualified Lead Independent Directors, Dinesh Hasija, Alan Ellstrand, Jason W. Ridge, Jon Johnson

Strategy, Entrepreneurship and Venture Innovation Faculty Publications and Presentations

Research SummaryThe lead independent director (LID) position was adopted primarily to increase the efficiency of the monitoring function of the board. However, evidence of whether and how LIDs influence board monitoring has been limited. We apply and test the theoretical quad model in the context of the LID to examine whether selecting a qualified LID helps improve monitoring within the board. We argue that when a board appoints a qualified LID, it improves overall board monitoring, along with board meeting facilitation and interpersonal interactions between the board and shareholders. Using a sample of US firms, we find that firms that …

Bandwagon Behavior In Major League Baseball, Daniel E. Erro

Master's Theses

This study investigates “bandwagon” behavior among Major League Baseball (MLB) fans by analyzing Google search interest data from 2004 to 2019. Drawing on publicly available information from Google Trends, the analysis explores how fluctuations in search activity align with team performance during both the regular season and postseason. Hierarchical linear models are used to estimate expected levels of fan interest based on team performance and market characteristics. Deviations from these expectations during the regular season are interpreted as evidence of bandwagon or anti-bandwagon behavior. A drop-off in interest following playoff elimination is also examined to capture shifts in fan attention …

Uni Political Science Newsletter, V20, 2024-25, University Of Northern Iowa. Department Of Political Science.

Political Science Newsletter

Contents:

--- From the Department Head
--- UNI Creates Center for Civic Education, Hires Director
--- Panthers Vote Recognized
--- Deputy Secretary of State Visits Campus
--- Celebrating Leaders in Public Service
--- Women in Public Service
--- You're Next Leadership Conference 2025
--- Model UN
--- Vajpeyi Fellowship
--- Iowa Human Rights Research Conference
--- Student Research
--- Montalvo Receives Lux Service Award
--- Purple & Old Gold Award
--- Congratulations 2024-25 Graduates
--- Faculty Updates
--- Keller Receives Gold & Bold Award
--- Alumni, Friends Recognized with President's Distinguished Award
--- Alumni Updates

Rationale And Justification Of The Overarching Principles In The Governance Maturity Framework, Janna Wong, Eugene K. B. Tan, Steve Loh

Lien Centre for Social Innovation: Research

This research addresses the lack of a unified framework for measuring the governance maturity of impact organisations across countries with diverse legal landscapes and cultures, which complicates international assessment and collaboration. In response, we propose a governance framework tailored to the legal context of six countries: India, Indonesia, Malaysia, the Philippines, Singapore, and Thailand. Our analysis identifies six overarching principles embedded in the non-profit laws of the six countries: (1) purpose and impact, (2) leadership, (3) integrity, (4) communication, (5) efficacy, and (6) financial transparency and accountability. These six overarching principles form the proposed framework, which was operationalised and further …

A Post-Dobbs World: More Than One Right To Privacy Under Attack, Sarah Jane Catarozoli

UC Law SF Journal on Gender and Justice

No abstract provided.

Riding For The Brand: Advancing Leadership Development In The Poly Royal Rodeo Program, Jack Busch

Agricultural Education: Graduate Internship Reports

While the Poly Royal Leadership Class provides a valuable platform for student involvement in large scale event planning, the structure lacked consistency in leadership development methods, project management tools, and hands-on training simulations, resulting in uneven engagement, limited collaboration efficiency, and varied preparedness levels among student leaders and committee members.

Secretive Sheriffs: Opacity And Variation In California's Jail Responses To Covid-19, Aparna Komarla, Hadar Aviram

Nevada Law Journal

No abstract provided.

Unarresting School Safety, Maryam Ahranjani

Nevada Law Journal

No abstract provided.

Decades Of Indifference And Failures In Accountability In The Provision Of Medical Care In Federal Prisons, Nicole B. Godfrey

Nevada Law Journal

No abstract provided.