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Comprehensive Characterization Of Purified Naringinase: Effect On Naringin Content, Antioxidant Activity, Phenolic Profile, And Grapefruit Juice Quality, Arzu İmece, Memnune Şengül, Bülent Çeti̇n, Ömer İrfan Küfrevi̇oğlu, Arzu Öztürk Kesebi̇r Jun 2025

Comprehensive Characterization Of Purified Naringinase: Effect On Naringin Content, Antioxidant Activity, Phenolic Profile, And Grapefruit Juice Quality, Arzu İmece, Memnune Şengül, Bülent Çeti̇n, Ömer İrfan Küfrevi̇oğlu, Arzu Öztürk Kesebi̇r

Turkish Journal of Agriculture and Forestry

Bitterness arising from naringin is a problem in citrus juices, especially grapefruit juice, in terms of consumer preference. Naringinase enzyme is used to eliminate the bitterness. In this study, naringinase was extracellularly extracted, isolated, and characterized from an Aspergillus niger strain in different media. The extracted enzyme was added to grapefruit juice at different concentrations (0.1%, 0.5%, 1%) (0.078, 0.39 and 0.78 EU) and stored at different temperatures (25, 35, and 45 °C) for 5 h. At the end of the first and fifth h, the amount of naringin, physicochemical properties, phenolic profiles, and antioxidant activities of the grapefruit juice …


Antiinflammatory Mechanisms Of Barley-Based Functional Foods Beyond Diabetes Management, Hafiz Ghulam Muhu Din Ahmed, Adnan Noor Shah, Muhammad Ahtasham Mushtaq, Xiaomeng Yang, Jiazhen Yang, Xia Li, Li’E Yang, Xiaoying Pu, Yawen Zeng Jun 2025

Antiinflammatory Mechanisms Of Barley-Based Functional Foods Beyond Diabetes Management, Hafiz Ghulam Muhu Din Ahmed, Adnan Noor Shah, Muhammad Ahtasham Mushtaq, Xiaomeng Yang, Jiazhen Yang, Xia Li, Li’E Yang, Xiaoying Pu, Yawen Zeng

Turkish Journal of Agriculture and Forestry

This review article investigated the antiinflammatory properties of barley, emphasizing its benefits beyond diabetes management. Barley, historically valued for its nutritional and medicinal properties, is rich in bioactive compounds such as beta-glucans, phenolic acids, and flavonoids. These compounds are known for their significant antioxidant and antiinflammatory activities. This study highlights the multifaceted mechanisms through which barley reduces systemic inflammation, including the enhancement of gut microbiota composition, the production of beneficial short-chain fatty acids, and the modulation of immune responses. Beta-glucans in barley lower cholesterol, and regulate glucose levels, while phenolic acids and flavonoids inhibit proinflammatory enzymes and cytokines, thereby reducing …


Effects Of Commiphora Myrrha Resin Extract/Nanosilver On Immune Cells, Pathogen, And Breast/Colon Cancer Cell Line Growth, Mohammad Y. Alshahrani, Essam H. Ibrahim, Abeer S. Alahmari, Mona Kilany, Ramadan Taha, Haitham I. El-Mekkawy, Amr Ahmed El-Arabey, Ahmed Ezzat Ahmed Jun 2025

Effects Of Commiphora Myrrha Resin Extract/Nanosilver On Immune Cells, Pathogen, And Breast/Colon Cancer Cell Line Growth, Mohammad Y. Alshahrani, Essam H. Ibrahim, Abeer S. Alahmari, Mona Kilany, Ramadan Taha, Haitham I. El-Mekkawy, Amr Ahmed El-Arabey, Ahmed Ezzat Ahmed

Turkish Journal of Agriculture and Forestry

Commiphora myrrha grows in various places of the world and is used for many purposes. The objectives of this study were to examine the biological influences of C. myrrha resin extract (MRE) alone or with its biogenic nanosilver on microbial, immune, and cancer cell growth. C. myrrha resin was boiled to prepare the MRE. Functional groups in the MRE were explored using Fourier-transform infrared spectroscopy (FTIR). MRE was used to synthesize nanosilver that was characterized using an ultraviolet-visible (UV-Vis)-spectrophotometer and X-ray diffraction. In vivo experiments included the untreated group (G1) and MRE-orally treated group (G2). Cancer cell lines, HCT-116 (colon) …


Quantum Management: A Revolution In The Future Of Management Science And Business Practice, Bartosz Niedzielski Jun 2025

Quantum Management: A Revolution In The Future Of Management Science And Business Practice, Bartosz Niedzielski

Studia i Materiały Wydział Zarządzania Uniwersytet Warszawski

Purpose: The article aims to propose a nominal definition of quantum management and analyze the differences between the classical and quantum paradigms of management, with particular emphasis on their impact on organizational structure and decision-making processes.

Methodology: The article is based on a synthetic literature review concerning the application of quantum theory in management sciences, including publications from bibliometric databases such as Scopus, Web of Science, and Elsevier. The review focuses on the theoretical and practical differences between the classical and quantum approaches to management. Additionally, a comparative method is used to identify key differences between these two …


Water Flowing Down Wall Street, Vanessa Casado Pérez Jun 2025

Water Flowing Down Wall Street, Vanessa Casado Pérez

Minnesota Law Review Vols. 106:2 onward (2021-present)

Water scarcity is a perennial problem with dire consequences for the United States and governments around the world. A lack of adequate water resources is a systematic cause of environmental harm, economic damage, and societal division. Climate change has exacerbated these problems making water even more valuable and essential. Financial actors have turned water into the new oil. These large financial actors profiteer from buying and selling water without any interest in its actual use as an input of production. Instead, they typically seek to hold these rights until dire situations, like droughts and fires, cause temporary, but large, spikes …


Green Biosynthesis Of Cobalt Oxide Nanoparticles Using Saccharum Munja Leaf Extract As A Catalyst For Callus Induction In Carnation (Dianthus Caryophyllus L.) Plants, Ishtiaq Ahmad, Sameed Arshad Chaudhry, Maryam Maryam, Aysha Arif Chahel, Riaz Ahmad, Mehmet Ramazan Bozhüyük, İbrahi̇m Bozkurt, Magda Abdel-Rahman, Konstantin Korolev Jun 2025

Green Biosynthesis Of Cobalt Oxide Nanoparticles Using Saccharum Munja Leaf Extract As A Catalyst For Callus Induction In Carnation (Dianthus Caryophyllus L.) Plants, Ishtiaq Ahmad, Sameed Arshad Chaudhry, Maryam Maryam, Aysha Arif Chahel, Riaz Ahmad, Mehmet Ramazan Bozhüyük, İbrahi̇m Bozkurt, Magda Abdel-Rahman, Konstantin Korolev

Turkish Journal of Agriculture and Forestry

The common name of a wild grass native to Pakistan with both edible and medicinal properties is Saccharum munja Roxb. (S. munja). Prior research has investigated various plant species for the green biosynthesis of nanoparticles to circumvent issues related to their physical and chemical production. This study presents the first evidence of synthesizing cobalt oxide nanoparticles (Co3O4NPs) using S. munja leaf extract (SMLE) as both a reducing and a capping agent. This study investigated their ability to induce in vitro callus formation in Dianthus caryophyllus L. (carnation). In this study, Co3O4NPs were synthesized using varying quantities of SMLE to achieve …


In Vitro Regeneration Potential Of Pistacia Integerrima And Pistacia Khinjuk Rootstocks: A Modeling Approach For Optimal Medium Formulation, Heydem Eki̇nci̇, Beki̇r Erol Ak Jun 2025

In Vitro Regeneration Potential Of Pistacia Integerrima And Pistacia Khinjuk Rootstocks: A Modeling Approach For Optimal Medium Formulation, Heydem Eki̇nci̇, Beki̇r Erol Ak

Turkish Journal of Agriculture and Forestry

Micropropagation involves the development of whole plants from small meristematic tissues by culturing them in vitro under aseptic conditions on a nutrient medium. However, identifying a single nutrient medium suitable for propagating Pistacia, a recalcitrant species, remains challenging. While some species exhibit good growth on Murashige and Skoog (MS) medium, Pistacia species generally yield insufficient results. To address this, a five-dimensional experimental design was developed using Design- Expert software (Stat-Ease Inc., Minneapolis, MN, USA). Thirty-three experimental databases were generated by the software using the modified I-optimal criterion. MS medium served as the control treatment. A response surface model (RSM) employing …


In Vivo Emergence And Seedling Growth Of Ornamental Pepper Seeds Under Diatomaceous Earth Treatments, Deni̇z Hazar Jun 2025

In Vivo Emergence And Seedling Growth Of Ornamental Pepper Seeds Under Diatomaceous Earth Treatments, Deni̇z Hazar

Turkish Journal of Agriculture and Forestry

Propagation by seeds is very useful in ornamental horticulture, especially for flowering plant production. Seed germination and seedling growth are the most sensitive plant developmental stages and, in nurseries, are under the influence of many biotic and abiotic stress factors. Diatomaceous earth is made from the fossilized remains of tiny aquatic organisms called diatoms, and diatomaceous earth as supplemental Si has been shown to be beneficial for plant growth, flowering, and nutrient content under both well-watered and water-stressed conditions. This study aimed to determine the effects of different methods and doses of Si-containing diatomite on in vivo seed emergence and …


Mechanisms Underlying Differential Helium Enrichment In Shale Gas Of Varying Structural Styles In The Southeastern Sichuan Basin, Xin Zhiyuan, Chen Jianfa, Wang Jie, Ma Yong Jun 2025

Mechanisms Underlying Differential Helium Enrichment In Shale Gas Of Varying Structural Styles In The Southeastern Sichuan Basin, Xin Zhiyuan, Chen Jianfa, Wang Jie, Ma Yong

Coal Geology & Exploration

Objective Shale gas reservoirs hold considerable helium reserves despite relatively low helium abundance, establishing them as a critical replacement for helium production growth. The southeastern Sichuan Basin exhibits diverse structural styles with varying preservation conditions, leading to an unclear understanding of the distribution characteristics and enrichment patterns of helium in shale gas. Determining the mechanisms behind the differential helium enrichment in shale gas is significant for the effective utilization of helium in shale gas.Methods Focusing on the typical shale gas reservoirs of different structural styles in the southeastern Sichuan Basin, this study explored the mechanisms underlying differential helium accumulation …


Effectiveness Of Seca Skin Public Relations Marketing Through Live Streaming On Tiktok, Mochamad Alvansa, Margareta Manalu Jun 2025

Effectiveness Of Seca Skin Public Relations Marketing Through Live Streaming On Tiktok, Mochamad Alvansa, Margareta Manalu

Journal of Indonesian Tourism and Policy Studies

This study examines the utilization of TikTok's live streaming feature as a public relations marketing strategy in the beauty industry. Using a qualitative descriptive method, the research is grounded in public relations marketing and live streaming theories. Through in-depth interviews, it explores how the beauty brand Seca Skin optimizes this feature to expand market reach, increase sales, and enhance consumer engagement. The findings reveal that Seca Skin successfully meets four key aspects of live-stream selling: Attractiveness, Trustworthiness, Expertise, and Purchase Convenience. These factors contribute to higher audience engagement, strengthened customer loyalty, and more effective purchasing decisions. Moreover, the study highlights …


Content Analysis Of @Fadiljaidi's Instagram As A Reference To Gen Z'S Followers Self-Existence, Syifa Alvernia Naufal, Margareta Manalu Jun 2025

Content Analysis Of @Fadiljaidi's Instagram As A Reference To Gen Z'S Followers Self-Existence, Syifa Alvernia Naufal, Margareta Manalu

Journal of Indonesian Tourism and Policy Studies

Social media has become the primary platform for generation Z to express themselves and establish their existence in the digital space One of the most influential social media platforms for generation Z is Instagram. Among the many Instagram influencers in Indonesia, Fadil Jaidi stands out for capturing his followers attention through humorous and relatable content. This study aims to analyze how the Instagram content of @fadiljaidi serves as a reference for self-existence among generation Z followers. Using a descriptive qualitative method, data were collected through in-depth interviews with five informants from generation Z who actively follow the Instagram account @fadiljaidi. …


Rekindling Cultural Legacy: The Interplay Of 4s Brand Gestalt Dimensions, Repurchase Intention, And Customer Citizenship Behavior For A Sustainable Traditional Product, Danny Ivan Rantung, Carolin Marhareita, Iwan Waani Kila, Deske Mandagi Jun 2025

Rekindling Cultural Legacy: The Interplay Of 4s Brand Gestalt Dimensions, Repurchase Intention, And Customer Citizenship Behavior For A Sustainable Traditional Product, Danny Ivan Rantung, Carolin Marhareita, Iwan Waani Kila, Deske Mandagi

Asia-Pacific Social Science Review

Despite the growing emphasis on the role of brand gestalt in marketing research, a discernible gap persists in empirical investigations regarding the interplay among brand gestalt, repurchase intention (RI), and customer citizenship behavior (CCB). More precisely, existing studies have yet to delve into the importance of brand gestalt within the distinctive context of traditional products and crafts. Focusing its investigative lens on Noken, a sustainable traditional woven bag with roots in Papua, Indonesia, this study seeks to deepen the understanding of the interplay between brand gestalt and customer behaviors in the context of a cherished traditional product. A research design …


Technology-Related Continuing Professional Development Activities In Supporting Digital Transformation In Academic Libraries In Uganda, Sarah Nakaziba, Patrick Ngulube Jun 2025

Technology-Related Continuing Professional Development Activities In Supporting Digital Transformation In Academic Libraries In Uganda, Sarah Nakaziba, Patrick Ngulube

School of Nursing & Midwifery, East Africa

Background of the study: To survive and thrive in a technologically advanced academic setting, librarians working in academic libraries need to revamp their competencies and knowledge through technology-rated continuing professional development.

Purpose: The purpose of this study was to examine the role of technology-related continuing professional development activities in enhancing digital transformation in selected Ugandan academic libraries.

Method: A convergent parallel mixed methods design was used to collect qualitative and quantitative data from six universities in Uganda. Qualitative data were obtained from six university librarians working in these universities, and quantitative data were collected from 76 librarians with a …


[Excerpt From] Evidence-Informed Health Policy (2nd Ed., Rev.), Jacqueline M. Loversidge, Joyce Zurmehly Jun 2025

[Excerpt From] Evidence-Informed Health Policy (2nd Ed., Rev.), Jacqueline M. Loversidge, Joyce Zurmehly

Sigma Publications: Book Excerpts

What happens in health policy at local, state, and federal levels directly affects patients, nurses, and nursing practice. Some healthcare professionals, though, are intimidated by the complex and often nonlinear policy process or simply don’t know how to take the first step toward implementing policy change. In the second edition of Evidence-Informed Health Policy, authors Jacqueline M. Loversidge and Joyce Zurmehly demystify health policymaking and equip nurses and other healthcare professionals with the knowledge, tools, and confidence to navigate the first of many steps into health policy. This book translates the EBP language of clinical decision-making into an evidence-informed health …


Granite Staters Wary Of One Big Beautiful Bill But Support No Taxes On Tips & Overtime 6/25/2025, Unh Survey Center Jun 2025

Granite Staters Wary Of One Big Beautiful Bill But Support No Taxes On Tips & Overtime 6/25/2025, Unh Survey Center

All UNH Survey Center Polls

A majority of New Hampshire residents do not want the U.S. Congress to pass President Trump's signature piece of legislation, the "One Big Beautiful Bill Act," amid bipartisan concern about the federal debt. Despite opposition to the overall bill, Granite Staters favor the provision of the bill to eliminate taxes on tips and overtime and are divided on work requirements for Medicaid and making the 2017 tax cuts permanent. Elon Musk is a largely unpopular figure in New Hampshire and nearly half of state residents believe the Department of Government Efficiency has had a negative effect on the country. Approval …


Mainers Disapprove Of One Big Beautiful Bill, Increasingly Disapprove Of Trump Handling Of Economy 6/25/2025, Unh Survey Center Jun 2025

Mainers Disapprove Of One Big Beautiful Bill, Increasingly Disapprove Of Trump Handling Of Economy 6/25/2025, Unh Survey Center

All UNH Survey Center Polls

Less than one-third of Maine residents want Congress to pass the "One Big Beautiful Bill Act," President Trump's major piece of legislation. However, a majority favor the provision of the bill which would eliminate taxes on tips and overtime. Elon Musk is an unpopular figure in Maine following his departure from the federal government and more than half of state residents believe the Department of Government Efficiency has had a negative effect on the country. Approval of Trump's handling of the economy among Mainers has declined since April and bipartisan majorities express concern about the federal debt.


Two-Thirds Of Vermonters Reject One Big Beautiful Bill Amid Bipartisan Concern About Budget Deficit 6/25/2025, Unh Survey Center Jun 2025

Two-Thirds Of Vermonters Reject One Big Beautiful Bill Amid Bipartisan Concern About Budget Deficit 6/25/2025, Unh Survey Center

All UNH Survey Center Polls

Most Vermont residents do not want Congress to pass President Trump's "One Big Beautiful Bill Act." Majorities oppose notable provisions of the Act such as making the 2017 tax cuts permanent and removing tax credits for electric vehicles and solar energy. Following his departure from the federal government, Elon Musk is an unpopular figure in Vermont and two-thirds of state residents believe the Department of Government Efficiency (DOGE) has had a negative effect on the country. Vermonters continue to disapprove of Trump's handling of the economy, immigration, and his overall job performance.


Core State Injury Prevention Program Listening Sessions Report June 2025 Report, Camille Velarde, Yvonnie Baik, Elena Martinez, Theresa Cruz Jun 2025

Core State Injury Prevention Program Listening Sessions Report June 2025 Report, Camille Velarde, Yvonnie Baik, Elena Martinez, Theresa Cruz

Reports & Documents

Background: Injury and violence remain pressing public health challenges in New Mexico, particularly in rural and underserved communities. To inform prevention strategies, the University of New Mexico Prevention Research Center partnered with the New Mexico Department of Health and local organizations to conduct community listening sessions focused on upstream approaches addressing shared risk and protective factors.

Methods: Four listening sessions were conducted in 2025 with stakeholders from county health councils and community organizations. Using a rapid qualitative analysis approach, researchers analyzed participant perspectives on local injury and violence concerns, familiarity with upstream frameworks, and communication preferences.

Results: Participants identified overlapping …


Law Enforcement Officers’ Perceptions About Antipolice Sentiment And Social Media As A Force Multiplier, Edward Peter Pope Jun 2025

Law Enforcement Officers’ Perceptions About Antipolice Sentiment And Social Media As A Force Multiplier, Edward Peter Pope

Walden Dissertations and Doctoral Studies

As a newly emergent form of mass communication, social media platforms can act as a force multiplier in fomenting negative and critical attitudes or viewpoints toward law enforcement officers and agencies. The purpose of this qualitative study was to examine the perceptions and lived experiences of law enforcement officers about antipolice sentiment and social media as a force multiplier. Amid growing concerns regarding public opinion and the impact of social media on law enforcement practices, more research was needed on how officers navigate and interpret these challenges. Data from in-depth interviews with 10 law enforcement officers were thematically analyzed to …


A Review Of Plant–Microbe Interactions In The Rhizosphere And The Role Of Root Exudates In Microbiome Engineering, Anagha Wankhade, Emma Wilkinson, David W. Britt, Amita Kaundal Jun 2025

A Review Of Plant–Microbe Interactions In The Rhizosphere And The Role Of Root Exudates In Microbiome Engineering, Anagha Wankhade, Emma Wilkinson, David W. Britt, Amita Kaundal

Biological Engineering Student Research

Microbial interactions within the rhizosphere are fundamental to plant health, influencing nutrient availability, stress tolerance, and pathogen resistance. Beneficial microbes, such as plant growth-promoting microbes (PGPMs), including bacteria and mycorrhizal fungi, enhance plant resilience through mechanisms like nutrient solubilization, phytohormone production, and pathogen suppression via antimicrobial compounds and siderophores. Root exudates, composed of sugars, organic acids, and secondary metabolites, act as chemoattractants that shape the rhizosphere microbiome by recruiting beneficial microbes. Microbial metabolites can, in turn, modulate plant physiology and exudate profiles, thereby reinforcing mutualistic interactions. Stress conditions alter exudate composition, enabling plants to attract specific microbes that aid in …


Telling The Library’S Story: A Step-By-Step Tutorial For Using Data Visualization To Show Impact On Teaching And Learning, David Vickers Loertscher, Michelle Young Jun 2025

Telling The Library’S Story: A Step-By-Step Tutorial For Using Data Visualization To Show Impact On Teaching And Learning, David Vickers Loertscher, Michelle Young

Learning Hub

This tutorial introduces school librarians to the use of data visualization tools for documenting and communicating their impact on teaching and learning. By leveraging accessible platforms like Google Forms and Google Sheets, the authors demonstrate how librarians can build dashboards and real-time visual reports to showcase co-teaching, instructional collaboration, and student engagement. The tutorial features real-world examples, highlights common data sources already available to librarians, and argues that dynamic visual storytelling is a powerful alternative to traditional library statistics.


Medical Populism And Epistemic Rights, Kurt Christian B. Tubera, Mark Anthony Dacela Jun 2025

Medical Populism And Epistemic Rights, Kurt Christian B. Tubera, Mark Anthony Dacela

Asia-Pacific Social Science Review

Medical populism, a performance-based political style that orchestrates antagonistic relations between the people and medical establishments, has served as a concept for analyzing the politicization of healthcare. With its four fundamental features, that is, invoking knowledge claims contrary to medical experts’ advice, simplifying discourse, dramatizing responses to public health crises, and forging divisions, medical populism compromises our access to accurate medical or public health information. Populist leaders abuse their epistemic authority and betray public trust when they propagate false information, medical or otherwise. And insofar as accurate medical or public health information is an epistemic good that we have the …


Synthesis Of Carboxymethyl Cellulose From Nypa Fruticans For Coating Metformin On Zn-Based Metal-Organic Framework Nanohybrid As A Bionanocomposite Drug Delivery System, Delviani Delviani, Viola Giary Rizkillah Maharani, Putri Nur Shadrina, Tri Warni, Regina Wan Azizah, Indra Lasmana Tarigan, Madyawati Latief Jun 2025

Synthesis Of Carboxymethyl Cellulose From Nypa Fruticans For Coating Metformin On Zn-Based Metal-Organic Framework Nanohybrid As A Bionanocomposite Drug Delivery System, Delviani Delviani, Viola Giary Rizkillah Maharani, Putri Nur Shadrina, Tri Warni, Regina Wan Azizah, Indra Lasmana Tarigan, Madyawati Latief

Makara Journal of Science

Diabetes is a common and rapidly spreading disease that affects 6.6% of the world’s population. Metformin hydrochloride (HCl) is an effective oral pharmacological treatment for type 2 diabetes mellitus (T2DM) patients because of its capability to reduce glucose levels and the risk of hypoglycaemia. However, gastrointestinal sensitivities to this drug can cause diarrhoea, nausea, vomiting and stomach ache. An alternative is controlled release technology by coating metformin with carboxymethyl cellulose (CMC) and zinc-metal-organic framework (Zn-MOF) through the encapsulation method. Therefore, this study aimed to coat metformin formulations using CMC in a Zn-MOF to control release into the body and minimise …


Isolation And Selection Of Bacillus Spp. As Candidate Probiotics For Use In Chickens, Adilah Adawiah, Komang Gede Wiryawan, Anja Meryandini Jun 2025

Isolation And Selection Of Bacillus Spp. As Candidate Probiotics For Use In Chickens, Adilah Adawiah, Komang Gede Wiryawan, Anja Meryandini

Makara Journal of Science

The growth rate of chickens can be improved by using probiotics as alternatives to antibiotics. Bacillus spp. as probiotics are particularly beneficial due to ability to form spores, which remain stable as commercial products over extended periods. This study aimed to isolate and select Bacillus spp. from Jasinga soil as probiotic candidates for chickens. A total of 15 isolates obtained of these, 12 were identified as Bacillus spp based on microscopic observations and screening test including ascertaining hemolysis, protease, amylase, and cellulase activities. Only six isolates exhibited gamma hemolysis and the ability to hydrolyze proteins, starch, and cellulose. Isolates BTJ1.1, …


Integrated Proteomic And Targeted Next Generation Sequencing Reveal Relevant Heterogeneity In Lower-Grade Meningioma And Anxa3 As A New Target In Nf2 Mutated Meningiomas, Maryam Shah, Yeasmin Akther, Claire Adams, Matt Banton, Vikram Sharma, Emanuela Ercolano, David A Hilton, Kathreena M. Kurian, Liyam Laraba, Waldemar Woznica, David Parkinson, Leandro Jose De Assis, Oliver Hanemann Jun 2025

Integrated Proteomic And Targeted Next Generation Sequencing Reveal Relevant Heterogeneity In Lower-Grade Meningioma And Anxa3 As A New Target In Nf2 Mutated Meningiomas, Maryam Shah, Yeasmin Akther, Claire Adams, Matt Banton, Vikram Sharma, Emanuela Ercolano, David A Hilton, Kathreena M. Kurian, Liyam Laraba, Waldemar Woznica, David Parkinson, Leandro Jose De Assis, Oliver Hanemann

Peninsula Medical School

Background: Meningiomas, the most common primary brain tumours, are classified by the World Health Organization (WHO) into grades 1, 2, and 3. Some grade 1 tumours exhibit increased clinical aggressiveness, with the biallelic mutation of NF2 being the most frequently reported. Methods: In our study, we analysed the most common driver mutations (NF2, AKT1, KLF4, and TRAF7) in meningioma by genomics describing co-occurrences and new mutations. Furthermore, tumour tissue bearing the driver mutations was analysed by proteomics. The relevance of the specific target found in the most common driver mutation in meningiomas (NF2) was validated in vitro using both lower …


Chemotype- And Target-Driven Genome Mining For A New Natural Product Inhibitor Of Bacterial Peptide Deformylase, Jonas H Costa-Martini, Eva E Adams, Chad W Johnston Jun 2025

Chemotype- And Target-Driven Genome Mining For A New Natural Product Inhibitor Of Bacterial Peptide Deformylase, Jonas H Costa-Martini, Eva E Adams, Chad W Johnston

Faculty, Staff and Students Publications

Antibiotics are essential for modern medicine, but their use drives the evolution of antimicrobial resistance (AMR) that limits the long-term efficacy of any one drug. To keep pace with AMR and preserve our ability to treat bacterial infections, it is essential that we identify antibiotics with new structures and targets that are not affected by clinical resistance. Historically, most developmental candidates for antibiotics have come from microbial natural products, as they feature chemical structures and biological activities that have been honed over millions of years of evolution. Unfortunately, as classical bioactivity screens for natural product discovery are blind to the …


Mediating Role Of Self-Efficacy In The Association Between Fatigue And Depressive Symptoms In Females With Rheumatoid Arthritis, I-Yu Hsiao, Hanoch Livneh, Chieh-Tsung Yen, Ming-Chi Lu, Wei-Jen Chen, Tzung-Yi Tsai Jun 2025

Mediating Role Of Self-Efficacy In The Association Between Fatigue And Depressive Symptoms In Females With Rheumatoid Arthritis, I-Yu Hsiao, Hanoch Livneh, Chieh-Tsung Yen, Ming-Chi Lu, Wei-Jen Chen, Tzung-Yi Tsai

Counselor Education Faculty Publications and Presentations

Background and Objectives: Extant research on the relationship between fatigue and depression in people with rheumatic diseases portrays a divergent picture. While caring for persons with this medical condition, one issue that represents individual confidence in carrying out specific tasks, namely self-efficacy level, has attracted significant attention. Yet, the information regarding whether self-efficacy may pose a clue linking these two major symptoms is still unknown. The aim of this study, therefore, is to examine whether self-efficacy mediates the association between fatigue and depressive symptoms among persons with rheumatoid arthritis (RA). Materials and Method: A cross-sectional study of 224 …


Environmental Consciousness And Pro-Environmental Behavior On Waste Management Of Secondary School Students, Siwaporn Phupan, Jidapa Koomklang, Somsak Amornsiriphong, Dhanakorn Mulaphong, Yuthpong Chantrawarin, Khemtida Petchtam, Shanana Rodsoodthi, Sauwakon Ratanawijitrasin Jun 2025

Environmental Consciousness And Pro-Environmental Behavior On Waste Management Of Secondary School Students, Siwaporn Phupan, Jidapa Koomklang, Somsak Amornsiriphong, Dhanakorn Mulaphong, Yuthpong Chantrawarin, Khemtida Petchtam, Shanana Rodsoodthi, Sauwakon Ratanawijitrasin

Asia-Pacific Social Science Review

The young generation is considered as one important group that is driving societies to more sustainable development. This study focuses on personal attributes—environmental consciousness and pro-environmental behavior—in the context of youth. The purposes of this study are (a) to analyze the levels of environmental consciousness and pro-environmental behaviors on waste management of secondary school students and (b) to analyze the components of environmental consciousness attributed to Thai youth. This study employed a cross-sectional survey design. The research sample was 414 secondary school students. Overall, the results showed that the overall environmental consciousness of secondary school students is at a high …


An Exploratory Study On University Students’ Perceptions Of Flagship Species: Implications For Sustainable Tourism, Tairan Huang, Chuan Hu, Minzhi Xia, Ziyu Liu, Weishan Zhou, Robert Charles Capistrano Jun 2025

An Exploratory Study On University Students’ Perceptions Of Flagship Species: Implications For Sustainable Tourism, Tairan Huang, Chuan Hu, Minzhi Xia, Ziyu Liu, Weishan Zhou, Robert Charles Capistrano

Asia-Pacific Social Science Review

This research explores the perceptions of university students in relation to flagship species in Hainan, China, and its implications for sustainable tourism. The province has an enormous wealth of biodiversity with great development potential and value for tourism. However, there is little or no empirical evidence about Chinese students’ interest in flagship species, their conservation, or their contribution to sustainable tourism in general. The study utilized a mixed method approach through an explanatory sequential design, beginning with a self-administered survey among university students in Hainan, recruiting 531 participants, followed by individual interviews with 14 students. The results have implications for …


An Analysis Of The Role Of Sugar Industry Leaders In The Formulation Of Sugar-Sweetened Beverages Excise Tax Using Advocacy Coalition Framework, Samantha Franchezka S. Ching, Sherwin E. Ona Jun 2025

An Analysis Of The Role Of Sugar Industry Leaders In The Formulation Of Sugar-Sweetened Beverages Excise Tax Using Advocacy Coalition Framework, Samantha Franchezka S. Ching, Sherwin E. Ona

Asia-Pacific Social Science Review

This paper examines the case of the Philippines in formulating its sugar-sweetened beverages (SSBs) excise tax policy through the lens of the Advocacy Coalition Framework (ACF). This case study used qualitative techniques to establish the networks and analyze the dynamics and interactions between the local sugar industry leaders and beverage manufacturing companies, as well as their advocacy strategies that influenced policy brokers from the government. The paper also highlights the complexities and the delicate balance needed to reconcile the differing interests of well-established political and economic groups and their effects on policy formulation. Their interactions were examined through the ACF, …