Digital Commons Network^™

Strategies To Improve Project Portfolio Management In The Pharmaceutical Industry, Emely Nhi Thi Ai Nguyen

Walden Dissertations and Doctoral Studies

Poor management of pharmaceutical project portfolios can negatively impact a pharmaceutical company’s product development and profitability. Project portfolio managers must ensure the successful development of new products in the pharmaceutical pipeline as the financial investment in new product development is significant and if not managed effectively can negatively impact profitability and prevent launch of new treatment therapies. Grounded in the project portfolio management framework, the purpose of this qualitative pragmatic inquiry study was to explore successful project portfolio management (PPM) strategies that drug project portfolio managers use to contribute to business success. The participants were six employees that managed portfolios …

Social Media Vetting Governance And The Impact On Hiring Capacity, Jimmy Lampkin

Walden Dissertations and Doctoral Studies

Human resource managers are concerned with weak social media vetting governance, as it is the number one predictor of reduced organizational capacity to hire candidates. Grounded in Lewin’s Situational Strength Theory, the purpose of this quantitative correlational project was to examine the relationship between social media vetting governance and organizational capacity to hire. The participants were 500 human resource leaders and hiring managers from organizations in the southwestern United States who completed the Job-Related Situational Strength Questionnaire and the Decision to Hire Scale. Although a priori power analysis required a minimum of 103 participants to detect a medium effect size, …

An Alternate History Of Chevron, With A Lesson For Today, Michael Herz

Fordham Environmental Law Review

It is a banal truism that judicial deference to agency decisionmaking enables the executive branch to pursue its agenda, whatever that agenda may be. That was obvious to all in the early years of the Chevron decision, which was greeted enthusiastically on the right and skeptically on the left. In Chevron itself, and for a while thereafter, deference advanced the Reagan deregulatory program. Over the years, a subtler conclusion gained consensus: overall and in the long haul, judicial deference is likely to have a net pro-regulatory impact. Hence the right’s hardened opposition to Chevron leading up to its demise. But …

Modeling, Control, And Learning For Whole-Body Manipulation With Large-Scale Soft Robots, Curtis C. Johnson

Theses and Dissertations

This dissertation addresses the challenge of enabling soft robots to perform contact-rich manipulation tasks by overcoming limitations in hardware, modeling, control, and learning. First, we present hardware advancements with PneuDrive, a pneumatic control system for actuating soft robots. We also introduce Baloo, a hybrid soft-rigid robotic torso which achieves a single-arm payload capacity of 19.3 kg and robust whole-body grasping capabilities. We also develop a full-body tactile sensing system enabling piezoresistive sensor arrays to cover large areas (1 square meter) with over 8000 distributed sensing points. Second, we focus on developing tractable dynamic models based on the Recursive Newton-Euler algorithm …

Design And Optimization Of Anode Catalysts For Direct Ethanol Fuel Cells: Advances And Challenges In C-C Bond Activation And Selective Modulation Of The C1 Pathway, Kai-Chi Qin, Meng-Tian Huo, Yu Liang, Si-Yuan Zhu, Zi-Hao Xing, Jin-Fa Chang

Journal of Electrochemistry

Direct ethanol fuel cells (DEFCs) are a promising alternative to conventional energy sources, offering high energy density, environmental sustainability, and operational safety. Compared to methanol fuel cells, DEFCs exhibit lower toxicity and a more mature preparation process. Unlike hydrogen fuel cells, DEFCs provide superior storage and transport feasibility, as well as cost-effectiveness, significantly enhancing their commercial viability. However, the stable C–C bond in ethanol creates a high activation energy barrier, often resulting in incomplete electrooxidation. Current commercial platinum (Pt)- and palladium (Pd)-based catalysts demonstrate low C–C bond cleavage efficiency (

Staff Education To Use The Patient Health Questionnaire-9 To Improve Identification Of Depression Among Mental Health Clients, Lukresia Bhwanshe Kawira

Walden Dissertations and Doctoral Studies

This doctoral project was an educational intervention to improve depression screening in a health clinic through standardized training using the Patient Health Questionnaire-9 (PHQ-9). The targeted practice issue was the variable use of the PHQ-9 which led to possible misdiagnosis or underdiagnosis of depression, a critically vital issue in nursing practice owing to the necessity of frontline mental status evaluation by nursing staff. The practice focused question was, for staff in a mental health clinic, will training on the use of the PHQ-9 tool increase knowledge toward the goal of improving the identification of depression among clients? Hence, the overall …

Southtalks Focus On 'Reading The South', Rebecca Lauck Cleary

University of Mississippi News

OXFORD, Miss. – The Center for the Study of Southern Culture focuses its programming for the University of Mississippi's 2025-26 academic year on the idea of "Reading the South." The center's SouthTalks events begin next week and support the theme.

Hiv-1 Controllers Possess A Unique Cd8+ T Cell Activation Phenotype And Loss Of Control Is Associated With Increased Expression Of Exhaustion Markers, Amber D. Jones, Zachary Capriotti, Erin Santos, Angel Lin, Rachel Van Duyne, Stephen Smith, Zachary Klase

Kimmel Cancer Center Papers, Presentations, and Grand Rounds

BACKGROUND: HIV-1 controllers are a rare population of individuals that exhibit spontaneous control of HIV-1 infection without antiretroviral therapy. Understanding the mechanisms by which HIV-1 controllers maintain and eventually lose this ability would be highly valuable in HIV-1 cure or vaccine research. Previous work revealed the ability of CD8+ T cells isolated from HIV-1 controllers to suppress HIV-1 replication in matched CD4+ T cells and PBMCs ex vivo and suggested the loss of control may be tied to CD8+ T cell exhaustion.

RESULTS: We explored whether CD8+ T cell exhaustion plays a role in the maintenance and loss of control …

Rest Easy, Applied Researcher: Latent Profile Analysis Is For You, Matthew A. Ng, Chelsea A. Lenoble, Allen Shorey, Abigale Gregory, Mark Kateli

Psychological Science Faculty Research & Creative Works

No abstract provided.

Peptide-Based Inorganic Nanoparticles As Efficient Intracellular Delivery Systems, Amir Nasrolahi Shirazi, Rajesh Vadlapatla, Ajoy Koomer, Anthony Nguyen, Vian Khoury, Keykavous Parang

Pharmacy Faculty Articles and Research

Background/Objectives: Peptide-based inorganic nanoparticles (PINPs) have emerged as promising candidates for intracellular delivery due to their unique structural and functional attributes. These hybrid nanostructures combine the high surface area and tunable optical/magnetic properties of metal cores (e.g., Au, Ag, Fe3O4) with the biocompatibility, targeting specificity, and responsive behavior of peptides. In particular, peptides with amphipathic or cell-penetrating features could facilitate efficient transport of molecular cargos across cellular membranes while enabling stimulus-responsive drug release in target tissues. Methods: We review key synthesis methods (especially green, peptide-mediated one-pot approaches), functionalization strategies (e.g., thiol-gold bonds, click chemistries), and characterization techniques (TEM, …

Library Publishing Research Agenda (2nd Ed.), Talea Anderson, Karen Bjork, Leigh-Ann Butler, Nina Collins, Perry Collins, Matthew Goldberg, Jonathan Grunert, Matthew Hunter, Michelle Lalonde, John Martin, Shawn Martin, John David Morgenstern, Talia Perry, Christopher Popovich, Liz Scarpelli, Janet Swatscheno, Willa Tavernier, Dan Tracy, Michelle Wilson, Mai Yamamoto

LPC Publications

This second edition of the Library Publishing Research Agenda builds on the foundation laid by the original 2020 publication, continuing to explore critical areas where research is needed to inform and strengthen practice in the field of library publishing. It offers updated and expanded exploratory overviews of six key topics (assessment, labor, accessibility, non-traditional research outputs, peer review, and partnerships), each including a contextual summary, refreshed or newly proposed research questions, and updated resources for further reading. This edition reflects new developments in the field and ongoing conversations within the community. It is intended to support current and future researchers, …

2025 August 28 - From My Notepads Newsletter, Brian E. Noland, Office Of The President, East Tennessee State University

From My Notepads: A Newsletter from President Brian Noland

No abstract provided.

Adult-Child Caregivers’ Fear And Coping Regarding The Risk Of Inheriting Alzheimer’S Disease, Rebecca Anne Ledbetter

Walden Dissertations and Doctoral Studies

Caring for elderly parents with Alzheimer’s disease (AD) poses two major challenges for adult-child caregivers: the tasks involved in taking care of ailing parents and also potentially living in fear of developing the same disease. This research examined how caregivers with such fear regard their vulnerability to AD and how they manage the stress that comes with caregiving for someone with a disease they dread developing themselves. This grounded theory study employed the appraisal theory of emotions and the theory of moods as frameworks and aimed to establish awareness regarding coping strategies that adult-child caregivers have about caretaking and their …

Influence Of Child Abuse On Youth Restiveness As Perceived By Security Personnel In Ilorin Metropolis, Kwara State, Falilat Anike Okesina

Jurnal Kajian Bimbingan dan Konseling

The rate at which Nigerian youths take up arms to perpetuate anti-social acts has become a major concern to the populace. This study investigated the influence of child abuse on youth restiveness as perceived by security personnel in Ilorin metropolis, Kwara State. The study was a survey research. The population of this study comprised all security personnel in Ilorin metropolis and 200 respondents were randomly selected for the study. A questionnaire entitled “Influence of Child Abuse on Youths Restiveness Questionnaire” (ICAYRQ) was used to collect data for the study. Percentage was used to analyse the demographic data. Mean and rank …

Contradictory Role Of Forgiveness Against Undergraduate Students’ Online Game Addiction Tendency: Two Preliminary Studies Before And During The Covid-19 Pandemic, Amalia Rahmandani

Jurnal Kajian Bimbingan dan Konseling

Two quantitative and cross-sectional preliminary studies were conducted to address the issues of forgiveness in the context of the tendency to online game addiction among university students in Semarang, Indonesia. A forgiveness scale comprising three dimensions of forgiveness, including forgiveness of self, others, and situations, as well as two separate scales of the tendency to online game addiction, was used. Samples consisting of two groups of online gamers were obtained using a convenience sampling technique. The sample size of Study 1, conducted prior to the onset of the COVID-19 pandemic, was 114 participants (Male = 98.25%) from four game centers. …

The Mediating Role Of Smartphone Usage In The Relationship Between Working Mothers And Children’S Social Interaction, Wulan Patria Saroinsong, Mochamad Nursalim, Azmawaty Binti Mohamad Nor

Jurnal Kajian Bimbingan dan Konseling

This study explores how smartphone usage acts as a mediator in the connection between working mothers and social interaction among children aged 3–6 years in East Java, Indonesia. Due to the insufficient reading and writing skills of children in this age range to complete questionnaires for the children’s interaction variable, data were gathered from their parents’ perspective, notably working mothers, who offered insights into their parenting behaviors and their children’s interaction patterns when using the smartphone. The research utilized a mediation analysis design to examine the relationships among the variables. A structured questionnaire was distributed to a sample of 400 …

Spartan Daily, August 28, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 165, Issue 4

August 28, 2025, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Industry Perspectives On Engineering Communication Skills For The Green Transition, Una Beagon, Stephen Harper, Paul Talbot

Irish Journal of Academic Practice

Effective communication skills are crucial in complex multidisciplinary, multistakeholder engineering projects, where engineers must articulate ideas, negotiate solutions and convey technical information across diverse audiences. However, despite their importance, communication skills are often undervalued in engineering curricula, as students and faculty may view them as peripheral to technical training. Through focus groups and interviews with practicing engineers in Ireland, the study explores communication’s role in professional tasks and stakeholder interactions. The study provides a flowchart outlining each stage of a civil and structural project. This was then used to identify key communication activities which are presented using the who, why …

Mantle Flow And Fault Zone Related Seismic Anisotropy Revealed By A Dense Linear Broadband Array In Southeast Tibet, Jing Wu, Yinshuang Ai, Stephen S. Gao, Peixi Huang, Fansheng Kong, Deke Xu, Jianguo Song, Xinyu Gao, Mengyi Wei, Long Li, Jien Zhang, Yanbin Zhang, Yingying Zhang

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Southeast Tibet, a key region for the southeastward extrusion of the Tibetan Plateau, remains debated in terms of its tectonic deformation in response to the ongoing collision between the Indian and Eurasian plates. In this study, we applied shear-wave splitting analysis of core-refracted phases recorded by a newly deployed dense seismic array and six permanent stations to delineate crustal and mantle deformation processes. The observed fast polarization directions are predominantly aligned NNW–SSE, while the splitting delay times vary across four sub-blocks. The anisotropy pattern suggests a dominantly asthenospheric origin, consistent with southeastward-directed mantle flow associated with the extrusion of the …

Hydrosocial Ocean Commons: Offshore Wind Energy In Oregon, Bryce Ashlyn Sprauer

Dissertations and Theses

The ocean has been culturally and legally conceptualized as a commons, a space of subsistence inherited by all. Enclosure or privatization creates overlapping jurisdictions of ocean space. The ocean is also the world's most significant carbon capture, absorbing billions of tons of anthropogenic carbon dioxide since the Industrial Revolution. Now, the ocean offers an additional opportunity to decarbonize energy production and reduce greenhouse gas emissions through 'new frontiers' of offshore wind technology; however, this potential is entangled within neoliberalism. Offshore wind is entering a fragmented legal landscape where the social-legal process of ocean jurisdiction remains contested. As the "new frontier" …

Bi-5756 Reduces Graft-Versus-Host Disease Through Cb1-Mediated Treg Upregulation, Sena Kim, Abdul-Jalil Dania, Sora Lim, Jaebok Choi

2020-Current year OA Pubs

Cannabinoid receptor 1 (CB1) has been implicated in multiple inflammatory diseases by regulating pro-inflammatory mediators or altering immune cell polarization. However, the expression and direct functional role of CB1 in T cells remain largely unexplored. Here, we demonstrate that primary murine T cells express CB1 and that its novel agonist, BI-5756, directly increases the frequencies of regulatory T cells (Tregs) in primary murine pan T cells after activation. In addition, BI-5756 exhibits an in vivo protective effect against graft-versus-host disease (GvHD), an allogeneic T cell-mediated inflammatory complication after allogeneic hematopoietic cell transplantation (allo-HCT), resulting in an improved overall survival with …

Beyond The 9-To-5: The Rx For Happier Healthcare Workers, Emily Calabro, Rodica Pop

Creating Healthy Work Environments (CHWE)

Purpose: This pilot feasibility study aimed to investigate the impact of flexible work schedules on the mental, psychological, and physical health of healthcare workers within a large hospital system.

Background: Traditional work schedules often negatively impact productivity, well-being, and job satisfaction. This study explored the feasibility and benefits of flexible workweeks among different nursing teams.

Methods: A quasi-experimental, mixed-methods, time-series design was implemented across a 12-hospital system with the partnership of 4-Day Global, a leading expert in flexible work schedules. Eligible participants were encouraged to flex their work hours daily or at least weekly. Clinical leaders ensured on-call coverage during …

Achieving Empowerment In Transition: Advice From Former Female Athletes, Ashlyn Hardie, Molly Harry, Kristi Oshiro, Marlene A. Dixon

Journal of Issues in Intercollegiate Athletics

Scholars have highlighted the various challenges college athletes encounter in their transition from sport. Yet, the strategies athletes adopt to navigate this transitory period require further examination. Thus, we leveraged Zimmerman’s Psychological Empowerment Model and Schlossberg’s Transition Theory to explore these strategies and associated processes in-depth. The sample for this study consisted of 20 former female athletes from the U.S. who played a college sport. Data was collected through semi-structured interviews. Findings revealed numerous strategies current and future female college athletes implement to mitigate the challenges present in their transition, specifically: Finding Acceptance, Be Proactive, Don’t Stop 100%, Embrace the …

Sport Media Consumption In Ncaa Division І Fbs Subdivision: A Panel Regression Model Using X/Twitter, Seungbak Lee, Minsoo Kang, Wonson Lim, Ju-Pil Choe, Brennan K. Berg

Journal of Issues in Intercollegiate Athletics

Athletic departments in collegiate sports have increasingly focused on enhancing sport consumer interest through social media. As social media usage continues to grow in college sports, understanding audience behavior on these platforms has become essential for athletic departments. This study examines the factors influencing consumer interest in Division I football teams’ X (formerly Twitter) accounts, utilizing a panel dataset comprising 18,221 team-day observations. Key determinants of changes in X followers were identified, including teams’ social media activity, on-field performance, scheduling events, and timing effects, with a focus on fan interest across temporal patterns such as month-to-month and day-to-day variations. The …

Sport Employees And Resilience: An Examination Of Organizational Change With Ncaa Conference Realignment, Hailee Hernandez, Claire C. Zvosec, Brent D. Oja

Journal of Issues in Intercollegiate Athletics

NCAA conference membership is critically important to institutions as it is closely associated with revenue generation (i.e., conference-wide revenue distribution, ticket sales, fundraising, etc.) in addition to institutional visibility and prestige. Therefore, universities may pursue conference realignment opportunities based on higher potential revenue, institutional and athletics financial stability, and increased notoriety. Over the past 20 years, there have been at least 80 cases of schools moving conferences at the Football Bowl Subdivision (FBS) level. As universities move conferences, employees within the athletics department are exposed to rapid change in organizational structure and are forced to adapt to new institutional, athletics …

Name, Image, And Likeness: A Critical Exploration Through Self-Determination Theory, Molly Harry

Journal of Issues in Intercollegiate Athletics

Through Self-Determination Theory (SDT) and Critical Discourse Analysis (CDA), this study explored college athletes’ experiences with Name, Image, and Likeness (NIL). Analyzing congressional testimonies from 10 current and recently graduated college athletes, this research highlighted how NIL fostered/constrained athlete development within the broader power structures of college sport. Findings revealed while NIL enhances self-determination through autonomy, competence, and relatedness, institutional discourses and governance mechanisms continue to regulate athlete development. Through Fairclough’s (1995) CDA framework, this study demonstrated how language throughout the athletes’ testimonies maintained/disrupted power dynamics which reinforced/challenged authority of the National Collegiate Athletic Association. The integration of SDT and …

Children’S Merchandising, Janelle Abbott

Silicon Valley Sociological Review

This paper explores how gender is constructed and reinforced through children's merchandising at Target, focusing on the toy, clothing, and greeting card departments. Using qualitative observational methods, I documented the ways in which colors, themes, and product placements subtly but powerfully separate items by gender. My findings reveal that gendered marketing is deeply embedded in retail environments and reflects broader societal expectations surrounding masculinity and femininity. These early messages shape children's self-perceptions, behaviors, and even long-term aspirations. Drawing on sociological theories of gender socialization and primary framing, as well as existing literature from Lips, Wade, and Ferree, this study situates …

Wearing Saris And Suits On Capitol Hillnavigating Elite White Spaces As South Asian American Women In Politics, Ambika Kathya Ramadurai

Silicon Valley Sociological Review

This preliminary research paper explores how South Asian American women navigate the elite white nature of U.S. politics, focusing on how they balance authentically representing their cultures and communities while navigating varying levels of power that prioritize individual advancement. Through initial interviews with South Asian American women in prominent political roles, and by applying established theoretical frameworks on identity-based hierarchies and social justice leadership, this study aims to offer insights into how South Asian American women approach the challenge of conforming to white standards in politics while maintaining their ethnic and cultural identities.

Peer-Led Sexual And Reproductive Healtheducation Programs At Universities, Madison Michelle Patrick

Silicon Valley Sociological Review

This applied research explores the accessibility, visibility, and comprehensiveness of sexual and reproductive health (SRH) education and services at universities, with a specific focus on contraceptive risk awareness. Recognizing college students as particularly vulnerable to misinformation regarding hormonal contraceptives, unintended pregnancy, and STI exposure, the study examines the role of university-provided SRH resources in mitigating these risks.

A mixed-methods content analysis was conducted on the SRH publicly-available web pages of four Northern California universities—Stanford University, San Francisco State University, Santa Clara University, and the University of California, Berkeley, chosen for their diversity in institutional identity. The research assessed each university’s …