Digital Commons Network^™

Changes In Alcohol Consequences And Food Addiction Symptoms Over Time In A Diverse Sample Of Emerging Adults With Histories Of Heavy Drinking, Mary Takgbajouah

Theses and Dissertations from DePaul University

During Emerging Adulthood (EA; 18-29), alcohol use (AU) peaks and eating disorders tends to have their onset. While AU typically decreases by the end of EA, this can be a time of increased isolation and lead to problematic, ongoing use with significant, negative consequences, such as depression, anxiety, or poor sleep. Research has noted similarities between disordered overeating and substance use, resulting in the conceptualization of food addiction (FA). Less is known about trajectories of FA, particularly during EA. Trait impulsivity, a tendency to act without planning or thinking of potential consequences, is associated with problematic AU and FA. Research …

Decomposition And Excavation Of War Memories And Massacres In Na Hong-Jin’S The Wailing, Grace Jung

BCES: Faculty Publications

This chapter examines Korean filmmaker Na Hong-jin’s The Wailing (2016) as an allegory of South Korea’s unresolved colonial and Cold War traumas, arguing that the film’s deliberate ambiguity, cacophony, and generic instability reflect the difficulty of recovering histories of violence that have been suppressed, erased, or inadequately mourned. While scholarship on South Korean zombie cinema has frequently interpreted the zombie through neoliberal capitalism, economic crisis, contagion, and social alienation, this chapter locates the Korean zombie within a longer history of civil war, massacres, sexual violence, and authoritarian state repression. Drawing on Heonik Kwon’s concept of Cold War “decomposition,” the zombie …

Hooks For Four-Dimensional Ecology Education (4dee) Teaching With Differing Audiences Of Nonmajors, Sara E. Scanga, Vikki L. Rodgers, Loren B. Byrne, Justin R. St. Juliana, Jon M. Honea, Erica S. Tietjen, George Middendorf

Arts & Sciences Faculty Publications

Nonmajors (i.e., undergraduate students not majoring in the natural sciences) constitute a majority of United States college graduates and are a large potential audience for courses with ecology content. However, nonmajors may be unmotivated to learn about ecology because they perceive it to be uninteresting and irrelevant to their everyday lives or career goals. Although the Four-Dimensional Ecology Education (4DEE) framework can be adapted for nonmajors courses as a starting point to improve student engagement, we suggest that nonmajors ecology instructors also use ecology hooks as effective gateways to 4DEE that will motivate and deepen student learning. Selecting and developing …

Chimeric Antigen Receptor Natural Killer (Car-Nk) Cells: From Preclinical Promise To Clinical Reality In Cancer Immunotherapy, Hunter Cassidy Cochran, Kevin Ashkan Ghobadi, Armin Ghobadi

2020-Current year OA Pubs

Chimeric antigen receptor (CAR) natural killer (NK) cell therapy represents an emerging frontier in cancer immunotherapy. CAR-NK cells offer the potential for "off-the-shelf" treatments with a favorable safety profile, due in part to their innate capacity for HLA-unrestricted tumor targeting and an absence of graft-versus-host disease. Landmark clinical studies using cord blood - derived CAR-NK cells and another employing iPSC-derived CAR-NK cells have reported impressive response rates, durable remissions, and minimal toxicity. Furthermore, a growing landscape of ongoing clinical trials is exploring innovative strategies to enhance persistence, overcome solid tumor challenges, and prevent antigen escape. These advances collectively underscore the …

Antitrust’S Consumer Tradeoffs, Samuel N. Weinstein

Articles

In modern antitrust law, courts are required to ask only one question: did the challenged action harm consumers? This Article asks a different question: which consumers? Over the last few decades, the Supreme Court has increasingly required antitrust plaintiffs to prove not only that they were harmed, but also that their harm outweighed any other consumers’ gains. The doctrine forces courts to pit groups of consumers against each other. In Amex, it was merchants against credit card holders. In Brooke Group, it was consumers buying a product during predation against consumers buying it during recoupment. In cases involving aftermarkets for …

Alterations In Region-Specific Gray Matter Volume Underlying Callous Unemotional Traits In Adolescents, Johannah Bashford-Largo, Ru Zhang, R James R Blair, Karina S Blair, Jaimie Elowsky, Matthew Dobbertin, Ahria J Dominguez, Melissa Hatch, Tyler Patrick, Sahil Bajaj

Faculty, Staff and Student Publications

Background: Callous-unemotional (CU) traits during adolescence, for example, shallow affect or lack of remorse, have been shown to be a risk marker for antisocial behavior. Only a few studies have investigated structural brain alterations underlying CU traits, and findings are inconclusive. The study examines CU symptomatology and gray matter volume (GMV) associations.

Methods: Structural brain MRI data were collected from a sample of 578 adolescents (60% male) with a mean age of 14.85 years (SD = 2.30; range = 10-19 years). CU traits were indexed via the Inventory for Callous Unemotional Traits (ICU). Region-wise volumetric parameters were obtained following parcellation …

Perioperative Antibiotic Administration Review: An Analysis Of Outpatient Surgeries At Ohiohealth Doctors Hospital., Rayyan Bhutta, Thomas Shneker, Samantha Currier, Alexander Caskey, Vincent Relli-Dempsey, Matthias Franzen, Samir Patel

Surgery Articles

INTRODUCTION: A vital part of preventing surgical site infections (SSIs) is perioperative antibiotic prophylaxis. Antibiotics must be administered within a certain window of time, usually 15 to 60 minutes prior to the surgical incision, for them to be effective. The most frequently utilized medication, cefazolin, can be administered quickly by intravenous push (IVP), but other medications, such as vancomycin and clindamycin, need longer infusion times. Antibiotic efficacy declines, and the risk of SSIs is increased when scheduling requirements are not followed. With special focus on time, dosage, and variation by surgery type, this study evaluates adherence to perioperative antibiotic administration …

Intelligence As An Instrument Of National Power: Lessons Learned From The Tensions Between Serbia And Kosovo, Vadym Chernysh

Journal of Strategic Security

Intelligence activity is unique; it can be a valuable and powerful tool in the hands of state leaders. Leaders should rely not solely on their perception or intuition to leverage the intelligence instrument of national power but rather on understanding this phenomenon and its inherent qualities. Often, political leadership may confuse the functions of intelligence and law-enforcement agencies, leading to the ineffective or inefficient use of national power instruments to achieve strategic goals. Leveraging the intelligence instrument of national power in prolonged conflicts with a larger adversary is a crucial aspect of statecraft. The role of intelligence can be vital …

The Institutional Effect: Democracies, Dictators And Diversionary Foreign Policy, Thomas Reilly

Journal of Strategic Security

The diversionary theory of war remains controversial in International Relations. The extant literature remains dominated by the study of democratic diversions and the use of warfare as the prime diversionary strategy. The sheer amount of work covering democratic diversions has created theoretical biases which are oft transposed to autocratic states, despite being largely unique to democratic processes. This article expands the traditional bounds of diversionary theory to provide a logic of autocratic diversions and diversionary strategies outside of war, presenting a theoretical framework which argues that institutionalization is the primary conduit through which the intended audience, benefit and preferred diversions …

Vulnerable State’S Foreign Policy Navigation In A Multipolar World: Discerning Ethiopia’S Security Engagement With Turkey, Henok Getachew

Journal of Strategic Security

Throughout its modern history, the Ethiopian state has operated in space that constraints its strategic autonomy. Since the mid of the twenty-first century, the Ethiopian state has consistently struggled to survive in the face of formidable challenges that manifested in the forms of irredentism, aggression, civil war, and external pressure. To deal with such security conundrums, maintaining strategic partnership for instance is not a new phenomenon in the tradition of Ethiopia’s foreign policy. Over the years, it has employed inter alia alliance, loose partnership, and asymmetric relationships with other states as well as collective security to ameliorate security risks originating …

Looking Inside Seychelles Beneficial Multi-Alignment Strategy Amidst India-China Competition, Gaurav Sen

Journal of Strategic Security

The article is designed to understand the political strategy of Seychelles. Seychelles situated in Western Indian Ocean has emerged as key player in the Indo-China competition. India and China are striving to exert influence over small island state, which hold strategic significance in the contested waters of the Indian Ocean. Seychelles has been adept at maintaining beneficial relationships with both India and China, despite its differing strategic interests. This article undertakes a detailed overview of Seychelles political strategy during India- China competition in the IOR. The first part of the paper devoted in understanding the importance of political strategy and …

Threat Perception In Taiwan: Trend And Implications, Christina Chen

Journal of Strategic Security

The rising tensions in the Taiwan Strait, driven by China’s growing aggression, have prompted Taiwan to explore ways to bolster its defense and deterrence capabilities. Given that successful deterrence requires the involvement of both military and civilian sectors, the Taiwanese public’s threat perception—specifically, how they view China as a security threat—becomes crucial. This article examines changes in Taiwan’s public threat perception of China. It finds that while Taiwan’s public threat perception has increased since the late 2010s, this shift is more nuanced. External events likely contributed to an overall rise in threat perception, but Chinese coercive actions were associated with …

The Element Of Surprise: Highly Maneuverable Satellites And Ssa, Simone L. Montandon

Journal of Strategic Security

Military, commercial, and civil space missions rely on accurate space situational awareness (SSA) to avoid collisions and inform the analysis of the threat environment. Historically, man-made objects in space have been highly predictable because their trajectories were mostly constrained within the orbit they occupied. However, fast-paced progress in engine/thruster technology, energy efficiency, and on-orbit servicing and refueling have allowed satellites to maneuver often and quickly within their lifespan. This added an element of unpredictability that adds further uncertainty to an operational environment that is already highly uncertain. This paper argues that solving this issue will require pursuing continued custody of …

Identifying Signatures Of Unidentified Aerospace Phenomena Through Structured Analytic Techniques, Joshua S. Pierson, Ms, Dss

Journal of Strategic Security

Unidentified Aerospace Phenomena (UAP) penetrate sovereign airspace and sea space with such proliferation that often national security entities are left baffled with how to detect, identify, and respond to such actions. Since World War II, these phenomena were reported to pace aircraft, maneuver at high speeds in an erratic fashion and increase speed to hypersonic velocity when starting from stasis. The study of UAP is shrouded in stigma, perplexing government mishaps, and academic inquiry focusing on the material aspects of UAP, leaving a gap in determining the exhibited capability and intent of these phenomena. The use of structured analytic techniques …

Sofs And Pmscs: Factors Of Stability And Change, Mirko Tasic

Journal of Strategic Security

The legitimacy of special operations forces (SOFs) and private military and security companies (PMSCs) often resides in a legal gray area, especially for those operating under the patronage of states that deviate from neoliberal standards and are sometimes labeled as criminal groups or terrorist organizations. This study aimed to develop a framework for categorizing the organizational and operational models of such SOFs and PMSCs. The three primary categories used were: mercantilistic, ideological, and ideological-mercantilistic. A comparative analysis of Iran’s Quds Force, Russia’s Wagner Group, and FR Yugoslavia’s JSO was conducted to better understand the impact of these and similar actors …

Ai-Enabled Terrorism: A Strategic Analysis Of Emerging Threats And Countermeasures In Global Security, Shai Farber

Journal of Strategic Security

The rapid advancement of artificial intelligence (AI) is transforming terrorist methods and counter-terrorism strategies, with far-reaching effects on global security. This paper examines how terrorists use AI for new attack tactics, propaganda, and coordination, while also evaluating the ethical, legal, and strategic challenges AI introduces into counter-terrorism. Through a systematic literature review and qualitative analysis, the study identifies key trends in AI's impact on security dynamics, highlighting its role in blurring the lines between peace and conflict. An analytical framework is proposed to navigate the complex landscape of AI-driven asymmetric warfare, providing practical insights for policymakers and researchers. The study …

Detecting Drone Threats At Stadiums And Public Venues: Overview, Operational Considerations, And Technical Implementation, Nathan P. Jones, John P. Sullivan, George W. Davis Jr.

Journal of Strategic Security

This article overviews the issue of drone threats to stadiums and public venues. It provides emergency managers and those defending this critical infrastructure with an overview, operational considerations, and a discussion of the technical implementation for defending these sites from drone threats through detection. It provides a discussion of the current limitations of countermeasures and legal frameworks relevant to drones. Throughout, this article uses real drone detection data from the Astroworld concert incident (November 2021) as a notional case study to illustrate the type of drone detection data emergency managers will contend with and what can be gleaned from it. …

Strategic Leadership In Security Media: Enhancing Community Safety Against Drug Abuse In Oman, Raed Awashreh, Saif Alshuhoomi,, Viola Gjylbegaj

Journal of Strategic Security

Rapid global development has led to increased security challenges, particularly regarding drug-related crimes. This study examines the role of strategic leadership in security media to enhance community security, focusing on drug abuse in Oman. Despite ongoing efforts to combat drug-related offenses, these crimes remain a significant threat to societal stability. The qualitative research involved in-depth interviews with 14 decision-makers, including 7 experts from Oman’s security media, police, and related institutions. It explores the effectiveness of security media campaigns in raising awareness and reducing drug use. Thematic analysis of the data revealed key challenges, including limited resources, outdated technologies, and insufficient …

Redbird Scholar, Vol. 11, No. 1 (Fall 2025), Illinois State University, Office Of The Vice President For Research And Graduate Studies

Redbird Scholar

No abstract provided.

Tirzepatide For The Maintenance Of Body Weight Reduction: Rationale, Design, And Baseline Characteristics Of Surmount-Maintain, Deborah B Horn, Louis J Aronne, Sean Wharton, Harold E Bays, Elisa Gomez-Valderas, Avigdor D Arad, Palash Sharma, Julia P Dunn, Cagri Senyucel, Clare J Lee

Faculty, Staff and Student Publications

Objective: SURMOUNT-MAINTAIN aims to evaluate the efficacy and safety of reducing the tirzepatide dose and/or continuing the maximum tolerated dose (MTD) versus placebo in maintaining body weight (BW) reduction achieved with tirzepatide MTD.

Methods: This Phase 3b, multicenter, randomized, parallel-arm, double-blinded, placebo-controlled, 52-week clinical trial is in progress comparing treatment with once weekly tirzepatide (5 mg and/or MTD of 15 mg or 10 mg) versus placebo in achieving BW reduction maintenance from the initial 60-week open-label weight-loss period on tirzepatide MTD, in adults with obesity (BMI ≥ 30 kg/m2 or ≥ 27 kg/m2 with ≥ 1 obesity-related comorbidity, excluding type …

Tofacitinib Ameliorates Campylobacter-Induced Intestinal Pathology By Suppressing Ifnγ Producing Ilcs And T Cells, Anna A Korchagina, Sergey A Shein, Wayne T Muraoka, Justin Nguyen, Qiangxing Chen, Anna A Tumanova, Austin W Todd, Carlos E Rivera, Rita Tamayo, Paolo Casali, Ekaterina Koroleva, Alexei V Tumanov

Faculty, Staff and Student Publications

Patients with autoimmune diseases are more susceptible to foodborne infections, which can be exacerbated by immunosuppressive therapy. Tofacitinib, a JAK/STAT pathway inhibitor, was recently approved for the treatment of ulcerative colitis, yet its effects on the pathogenesis of intestinal infections remain unclear. Here, we examined the impact of oral tofacitinib treatment in a mouse model of Campylobacter jejuni (C. jejuni) infection. Our results show that early tofacitinib administration attenuates intestinal pathology without affecting bacterial colonization. Specifically, tofacitinib suppressed CXCL1, CXCL2, CCL2 chemokine expression by intestinal epithelial cells, limiting recruitment of monocytes and neutrophils to the gut. In addition, JAK/STAT inhibition …

Tracking Change: A Follow-Up On The Culturally Adapted ¡Iniciando! La Adultez Program, Antonio F Pagán, Katherine A Loveland, Ron Acierno

Faculty, Staff and Student Publications

Introduction: Research on interventions for Latino young adults with Autism Spectrum Disorder (ASD) and their families often faces challenges in long-term engagement. This study aimed to assess the feasibility and effectiveness of the culturally adapted ¡Iniciando! La Adultez program through a long-term follow-up.

Methods: A cohort of Latino young adults with ASD and their families who participated in the ¡Iniciando! La Adultez program were followed for six months post-intervention. Participants were assessed at three and six months to evaluate continued engagement and outcomes. Retention rates at each follow-up point were calculated.

Results: The study demonstrated high retention rates, with 48 …

Healing Right Way: A Stepped Wedge Cluster Randomised Controlled Trial Aiming To Enhance Quality Of Life For Aboriginal Australian Survivors Of Stroke And Traumatic Brain Injury, Elizabeth Armstrong, Tapan Rai, Judith M. Katzenellenbogen, Sandra J. Thompson, Meaghan Mcallister, Natalie Ciccone, Deborah Hersh, Leon Flicker, Dominique A. Cadilhac, Erin Godecke, Graeme J. Hankey, Neil Drew, Colleen Hayward, Deborah Woods, Mel Robinson, Ivan Lin, Sanita Kratina, Jane White, Juli Coffin

Research outputs 2022 to 2026

Objective: To determine the effect of cultural security training (CST) for health professionals and access to an Aboriginal Brain Injury Coordinator (ABIC) for Aboriginal Australians with stroke or traumatic brain injury (TBI). Design: A stepped wedge cluster randomised controlled trial; the intervention package consisted of CST for hospital professionals and 6-month access to ABICs providing education, support, liaison and advocacy; the commencement order of the intervention phase was randomised. Setting: Four urban and four rural hospitals in Western Australia, 2018–2022. Participants: Aboriginal adults ≥ 18 years hospitalised with stroke or TBI. Main Outcome Measures: Primary outcome was quality of life …

Systematic Review And Meta-Analysis Of Microrna-7-5p Expression And Biological Significance In Head And Neck Squamous Cell Carcinoma, Rikki A.M. Brown, Michael Phillips, Andrew J. Woo, Omar Kujan, Stephanie Flukes, Louise N. Winteringham, Larissa C. Dymond, Fiona Wheeler, Brianna Pollock, Dianne J. Beveridge, Elena Denisenko, Peter J. Leedman

Research outputs 2022 to 2026

Background: Head and neck squamous cell carcinoma (HNSCC) is a prevalent malignancy with poor clinical outcomes. microRNA-7-5p (miR-7-5p) has been described as both a tumour suppressor and an oncomiR depending on the tissue context, but its role in HNSCC remains unclear. This study aimed to clarify the clinical significance and biological function of miR-7-5p in HNSCC by integrating data from multiple sources. Methods: A systematic review of the literature was conducted to identify studies analysing miRNA expression in human head and neck tissues. A meta-analysis of individual patient data from Gene Expression Omnibus (GEO), ArrayExpress, and The Cancer Genome Atlas …

The Consequences Of Habitual Rumination, Expressive Suppression, And Perceived Stress On Mental And Physical Health Among Older Adults, Eyal Gringart, Rodrigo Becerra, Andrea Smith

Research outputs 2022 to 2026

Background/Objectives: The current study aimed to investigate whether habitual rumination, suppression, and perceived stress predict poor mental and physical health as well as well-being in a group of older adults (aged 50 to 80 years) from a non-clinical community sample. Methods: The current study comprised a cross-sectional survey design with online self-report measures. It was predicted that higher levels of rumination, suppression, and perceived stress would predict lower levels of general health as well as well-being, and heightened levels of depression and anxiety. Results: Findings from the study indicated that both rumination and perceived stress significantly predicted heightened anxiety, heightened …

Overland With Ernst Heinen: A Newly Discovered 1864 Bridger Trail Diary, Caroline L. Gilson

Library Faculty Publications

In 1864, Joseph Ernst Johann Heinen, age 27, travelled from Illinois to California for a work opportunity. His route and travel experiences were recorded in a diary, which has been transcribed, with footnotes. Research and work was conducted by Gilson, along with DePauw University students. This article includes the full transcription of the 1864 diary, a biography of Ernst Heinen and notes on sources consulted.

Engaging And Empowering Future Female Surgeons: Development Of The Medical Student Section Of The Society Of Women In Urology, Allison G. Booher, Sasha Vereecken, Erin Kim, Neharika Penmetcha, Alexandra Aponte, Eman N. Chaudhri, Meghana Noonavath, Ibukunoluwa Omole, Joanna Orzel, Leigh Martin

School of Medicine Publications

Objective: To describe a replicable model for a large-scale, cross-institutional, and student-driven initiative to promote gender equity within surgical fields.

Methods: To address the lack of a national infrastructure to support female medical students pursuing careers in Urology, a historically male-dominated specialty, the society of women in urology (SWIU) established its medical student section, called SWIUdents, as a student-led initiative to offer mentorship, education, and networking resources for future female urologists. In 2022, SWIUdents convened its first medical student leadership board, comprised of two co-chairs and four subcommittees focused on membership, program implementation, mentorship, and community relations. SWIUdents membership was …

Assessing The Accuracy And Readability Of Chatgpt 4.0'S Original And Simplified Responses To Common Patient Questions Regarding Periacetabular Osteotomy, John M. Gaddis, Elias Arellano, Blake Martin, Yossef Alsabawi, Martin Salgado-Flores, Charles South, Pablo Castaneda, Joel Wells

School of Medicine Publications

Purpose: The study aimed to evaluate the accuracy, comprehensiveness, and readability of responses generated by ChatGPT 4.0 to 30 common patient questions about the Bernese periacetabular osteotomy (PAO).

Methods: Two fellowship-trained orthopaedic surgeons specializing in hip preservation selected thirty questions from a prior study identifying common PAO questions on social media. Each question was entered into ChatGPT 4.0, and the surgeons independently graded responses. Responses were evaluated using an established grading system. Accuracy and comprehensiveness were assessed based on the concordance of response content with current literature. Readability was analysed by calculating the Flesch-Kincaid Grade Level and Flesch-Kincaid Reading Ease. …

Deep Learning For Hate Speech Detection: A Comparative Study, Jitendra Singh Malik, Hezhe Qiao, Guansong Pang, Anton Van Den Hengel

Research Collection School Of Computing and Information Systems

Automated hate speech detection is an important tool in combating the spread of hate speech, particularly in social media. Numerous methods have been developed for the task, including a recent proliferation of deep-learning based approaches. A variety of datasets have also been developed, exemplifying various manifestations of the hate-speech detection problem. We present here a largescale empirical comparison of deep and shallow hate-speech detection methods, mediated through the three most commonly used datasets. Our goal is to illuminate progress in the area, and identify strengths and weaknesses in the current state-of-the-art. We particularly focus our analysis on measures of practical …

Genwardrobe: A Fully Generative System For Travel Fashion Wardrobe Construction, Peng Jin, Yilin Wen, Mingzhe Yu, Yunshan Ma, Rong Zheng, Jin‑Tu Fan, Chong Wah Ngo

Research Collection School Of Computing and Information Systems

With the increasing demand for outfit planning in real-world travel scenarios, the need for constructing a travel fashion wardrobe, a series of outfits tailored to a user's personalization and destination-specific context over a short travel period, has grown significantly. However, existing systems or works often focus on isolated factors and rely on retrieval-based methods, with insufficient utilization of generative models, limiting their adaptability to real-world travel scenarios. To address this issue, this study introduces GenWardrobe, a fully generative system for travel fashion wardrobe construction. GenWardrobe consists of three key modules: user query analysis, fashion knowledge retrieval via retrieval-augmented generation and …