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Lrp8 Is An Entry Receptor For Tick-Borne Encephalitis Viruses, Pengfei Li, Sean Hui, Zhenlu Chong, Michael N Nguyen, Stefanie P Muraro, Hana Janova, Hongming Ma, Shiqi Cao, Tomasz Kaszuba, Brian Imbiakha, Sathvik Palakurty, David A Price, Gaya K Amarasinghe, Daisy W Leung, Daved H Fremont, Michael S Diamond, Et Al.

2020-Current year OA Pubs

Orthoflaviviruses are a genus of arthropod-transmitted RNA viruses that infect humans and other vertebrate animals on a global scale, resulting in extensive morbidity and mortality. Among the orthoflaviviruses, tick-borne encephalitis viruses (TBEV) are an antigenic group that causes severe neurological disease in humans. However, the entry receptors for TBEV, which contribute to cell and tissue tropism, remain largely unknown. Because recent studies identified members of the low-density lipoprotein receptor (LDLR) family as possible receptors for some orthoflaviviruses and distantly related alphaviruses, we performed a targeted screen in transgenic cells expressing different LDLR members and identified LRP8 (also called ApoER2) as …

Enhancing Nitrogen Removal In High Permeability Bioretention Media: The Combined Role Of Biochar, Wood Chips And Hydraulic Design, Joshelyn Guimaray

USF Tampa Graduate Theses and Dissertations

Urban stormwater runoff can transport high nutrient loads to receiving waters, leading toeutrophication, harmful algal blooms, and the formation of hypoxic zones. Bioretention systems are a form of green infrastructure designed to mitigate these impacts, but their application in dense, ultra-urban environments is often limited by large land area requirements. This has led to the adoption of high permeability media (HPM) to accommodate higher hydraulic loading rates (HLRs) and reduce the system footprint. However, conventional HPM systems often show inconsistent removal of dissolved nitrogen species due to short hydraulic retention times (HRTs), a lack of organic carbon, and insufficient anoxic …

Optimising Drowning Prevention Counselling Through A Physician Maintenance Of Certification (Moc) Quality Improvement (Qi) Initiative, Tracy E Mccallin, Anthony R Arredondo, Elizabeth A Camp, Shabana Yusuf

Faculty, Staff and Students Publications

Drowning is the leading cause of death in children 1–4 years old in the USA. Paediatricians play an important role in giving anticipatory guidance on drowning prevention. This quality improvement initiative aimed to increase the rate of drowning prevention counselling with provision of educational materials to caregivers of children aged 0–10 years during clinical encounters in an outpatient setting.

We refined a previously published Texas state educational programme that included evidence-based counselling strategies across three Plan Do Study Act (PDSA) cycles, with the addition of preintervention baseline counselling phase during expansion of the programme nationally to 17 and 21 states …

Global Trends And Forecast Of Cardiovascular Diseases, Cancer, And Shared Risk Factors: Insights From The Gbd 2021, Chieh Y Koo, Bryan Chong, Jayanth Jayabaskaran, Srinithy Nagarajan, Silingga M Jauhari, Yiming Chen, Li L Tan, Anurag Mehta, Muhammad S Khan, Mark Muthiah, Derek Hausenloy, A M Richards, Dennis T Ko, Christian D Mallen, Eric A Secemsky, Mark Y Chan, Paaladinesh Thavendiranathan, Nicholas W S Chew, Mamas A Mamas

Faculty, Staff and Students Publications

Background: Cardiovascular disease (CVD) and cancer share multiple risk factors and are the leading causes of morbidity and death worldwide. This study aims to examine historical and projected trends of the combined CVD-cancer global estimates and their shared risk factors.

Methods: Death and disability-adjusted life years (DALYs) associated with CVDs, cancers, and their risk factors were obtained from the GBD (Global Burden of Disease) 2021 study. Historical estimates from 1990 to 2021 and forecast data from 2025 to 2050 were examined across age groups, regions, sociodemographic index, and sex.

Results: In 2021, CVD-cancer resulted in age-standardized DALY rates of 8009 …

Serum Response Factor Is Essential For Endometrial Function And Prevention Of Inflammatory Fibrosis, Ryan M Marquardt, Sara A Grimm, San-Pin Wu, Peter F Lais, Shu-Yun Li, Xin Xu, Erin Smithberger, David Cunefare, Charan Ganta, David Olson, Eunhee M Jeong, Jae-Wook Jeong, Bruce A Lessey, John P Lydon, Francesco J Demayo

Faculty, Staff and Students Publications

Pregnancy requires a supportive uterine environment facilitated by steroid hormone–regulated differentiation of endometrial stromal fibroblasts into decidual cells and tight control of inflammation. Serum response factor (SRF) is a widely expressed transcription factor essential for mesenchymal cell growth and differentiation with noted roles in hormonal regulation of muscle tissues but little characterization in reproductive organs. Here, we reveal that endometrial SRF is dysregulated in human endometriosis and is critical for female reproductive success in mice through regulation of endometrial stromal and epithelial cells. Immunohistochemical analysis identified decreased endometrial SRF expression in infertile endometriosis patient tissues. RNAi-based SRF knockdown in human …

Book Review: Robert J. Jarvis, The Neglected Amendments Of The U.S. Constitution: Text, History, And Interpretation, Jonathan E. Moore

ConLawNOW

This essay offers an engaging review of the casebook, The Neglected Amendments of the U.S. Constitution, by Professor Robert Jarvis. While most lawyers, and many nonlawyers, could readily identify many of the “big twelve” constitutional amendments, few are familiar with the other fifteen. This book focuses on the neglected fifteen, arguing they deserve sustained attention as historically and politically important today. Topics include several amendments potentially going in play, such as the Twenty-second limiting the president to two terms, Twenty-fifth on presidential succession and disability, Twenty-seventh on congressional pay raises, and the Ninth on rights retained by the people. …

An Interview With Dr. Chris Richardson, Elizabeth Reynolds Dds

Virginia Dental Journal

No abstract provided.

Deforestation Affecting Developing Nations, Nicole Villa

Sustainability Conference

Deforestation continues to be a growing problem around the globe, while it is affecting wildlife what can be overlooked is the challenges it’s creating for the livelihood of nations. This goes beyond losing the biodiversity of our ecosystems but social consequences with the scarcity of water in Malawi, rise in health risks in Democratic Republic of Congo and negative effects of agricultural expansion in Belize. Overall social conflict in these areas that are suffering to grow. Furthermore, I aim to cover the major challenges previously mentioned followed by counteracts of deforestation including action plan in Brazil, efforts of other countries …

Full Issue, Volume 4, Press Humboldt

CSU Journal of Sustainability and Climate Change

Volume 4, 2025

Assessing Antimicrobial Properties Of Plant-Derived Ellagic Acid Supplements, Noah S. Schuhmann, Andrew Mclaughlin, Julian Barrera

Humboldt Journal of Microbiology

Bacteria present in the human gut microbiota are affected by compounds with antimicrobial properties. Phenolic compounds extracted from plants have been shown to exhibit significant antimicrobial capacity at certain concentrations, which makes them an area of interest to researchers. Ellagic acid is one such phenolic compound, present in nuts and berries that many people consume on a regular basis. Supplements containing concentrated ellagic acid provide an additional source for the compound. It is known that, in the body, ellagic acid is metabolized into urolithins, which contribute to health through their anticancer and anti-inflammatory qualities. In this study, we investigated the …

Comparative Analysis Of Probiotic Viability In Alcoholic And Non-Alcoholic Kombucha, Isabella N. Cerrone, Brooke Pirkle, Danielle Williamson, Gianna Vendrell, Chloe Kraft

Humboldt Journal of Microbiology

Kombucha is a fermented tea beverage valued for its probiotic and antimicrobial properties that arise from complex molecular interactions between yeast, acetic acid bacteria (AAB), lactic acid bacteria (LAB), and metabolic byproducts of fermentation. With the rising demand for non-alcoholic versions of traditionally alcoholic kombucha beverages, ethanol reduction methods have become common, though their impact on probiotic viability and antimicrobial properties remains poorly understood. This study investigates the effects of ethanol removal on kombucha’s functional properties, including probiotic survival, antimicrobial activity, and organic acid composition (pH). We compared alcoholic and non-alcoholic versions of JuneShine kombucha across five flavors. Probiotic viability …

Elucidating The Relationship Between Water Quality And Antibiotic Resistance Of Rainwater Microbes Across Western Humboldt County, Theo P. Murphy, Eve Wendley, Justice Laskowski, Tyler Paredes

Humboldt Journal of Microbiology

Limited studies have been conducted regarding the fecal contamination and microbial dispersal through rainwater, with no known studies investigating the potential connection between antibiotic resistant microbes and water quality in rainwater. This study seeks to identify the presence of a correlation between water quality and incidence of antibiotic resistance in rainwater microbes. We hypothesize that there will be a correlation between these two variables. We additionally anticipate a high incidence of fecal contamination across rural and urban collection sites alike, with fecal contamination being more prevalent in rural areas than urban locals. To determine water quality, we measured the concentration …

Postoperative Pain Management In Older Patients, Stephanie Guercio, Andrea M. Bodine

Advances in Clinical Medical Research and Healthcare Delivery

Background: Postoperative pain management in the older population has been described as a complex topic with providers trying to balance pain control while minimizing adverse effects of decreased physiologic reserve such as delirium and decreased cognitive function. The goal of this study was to compare pain scores and pain medications prescribed at discharge between an older age group and a middle age group after an elective cholecystectomy.

Methods: We conducted a retrospective study at a community hospital in western Massachusetts collecting data from March 1, 2022, to February 28, 2023 using laparoscopic cholecystectomy CPT code. Included were patients between 50 …

The Role Of A Luxury Brand For The Professional Competitiveness Of Brazilian Business Women, Irene Raguenet Troccoli, Patricia Da Silva Leite, Joyce Gonçalves Altaf

Journal of Marketing and Consumer Behaviour in Emerging Markets

This qualitative article explores the significance of a luxury women’s shirt brand in fostering the professional competitiveness of Brazilian Generation Y women. It does this by identifying the personal values that motivate women to wear these shirts, based on the Means-End Theory. This theory was operationalized using the Soft Laddering technique and complemented by non-participant observation. The result is that these shirts play a role in securing respect – primarily professional, but also personal – from third parties for the wearers, helping them to perceive themselves as successful in their careers. This study is the first to examine the ability …

The Rider (2025-11-03), Daniela Martinez Salazar

The Rider Archives

Vol. 11, No. 10

Ada News - 11/3/2025, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Intranasal Delivery Of Extracellular Vesicles Derived From Human Bone Marrow Mesenchymal Stem Cells Dampens Neuroinflammation And Ameliorates Motor Deficits In A Mouse Model Of Cortical Stroke, Saviana Antonella Barbati, Chiara D'Amelio, Chiara Feroleto, Marta Morotti, Ida Nifo Sarrapochiello, Francesca Natale, Domenica Donatella Li Puma, Yolanda Gomez-Galvez, Elena Blanco-Suarez, Lorraine Iacovitti, Lucia Leone, Salvatore Fusco, Maria Vittoria Podda, Claudio Grassi

Department of Neuroscience Faculty Papers

Early treatment of ischemic stroke can significantly reduce disability and mortality rates. Stem cell-derived extracellular vesicles (EVs) have shown potential as therapeutics for neurological disorders. This study explored whether intranasal administration of EVs from human bone marrow mesenchymal stem cells (BM-MSCs) enhances forelimb motor function recovery in a mouse model of motor cortex stroke and investigated their mechanism of action, focusing on neuroinflammation. C57BL/6JRj mice received EV treatment of 0.1 × 10⁹ EVs per dose per day, 48 h post-stroke and twice weekly for four weeks. EV-treated mice showed significant improvement in forelimb deficits, as evaluated using a series …

Crow's Nest, November 3, 2025, Crow's Nest Staff

Crow's Nest

The November 3, 2025 issue of Crow's Nest.

The Impact Of Npo Credibility On Enterprise Brand Image In Cause-Related Marketing: A Study Based On The Mediating Effect Of Perceived Corporate Hypocrisy, Jun Wang, Ling Zheng, Xinyi Li, Chiquan Guo

Marketing Faculty Publications

In recent years, scandals regarding the malpractices of many nonprofit organizations (NPOs) for selfish ends have eroded public trust in them. Therefore, it is necessary to consider whether the credibility of NPOs, as one of the three key implementers in cause-related marketing (CRM) campaigns, has a transfer effect on enterprise brand image. The aim of the current study is to examine the relationship between NPO credibility and enterprise brand image, along with its underlying mechanism and boundary conditions. Drawing on the affect-transfer model as well as attribution theory, we propose a theoretical model. This model highlights the mediating role of …

The Echo: November 3, 2025, Taylor University

2025-2026 (Volume 113)

No abstract provided.

Social Media Sponsorship: Metrics And Strategies For Finding The Right Content Creator-Sponsor Matches, Shahryar Doosti, Stephanie Lee, Young Tan

Business Faculty Articles and Research

Social media video sponsorship, where sponsors partner with content creators to promote their brands, has become increasingly popular. Leveraging rich data on sponsored and nonsponsored videos on Facebook, we introduce two metrics, Content Similarity and Audience Closeness, to help sponsors find effective creator-sponsor matches. Content Similarity captures the thematic alignment between a creator’s content and a sponsor’s brand, whereas Audience Closeness measures how closely aligned a creator’s and sponsor’s audiences are within a social media network. We find that both metrics significantly increase video viewership, but their effects vary over time. Audience Closeness generates more immediate, short-term engagement, whereas …

Ohio University Faculty Senate Meeting Minutes November 3, 2025, Angela Brock

Faculty Senate Minutes

No abstract provided.

Human Kallikrein 2: A Novel Lineage-Specific Surface Target In Prostate Cancer, Fei Shen, Ryan Smith, Theresa Mcdevitt, Krista Menard, Shaozhou Tian, Gerald Chu, Ruchi Chaudhary, Jennifer Mccann, Halley Oyer, Sherry C. Wang, Steven Max, Peter Francis, William K. Kelly, Charles G. Drake

Kimmel Cancer Center Faculty Papers

PURPOSE: Targeted therapies for metastatic prostate cancer are limited, highlighting the need for novel drug targets and mechanisms of action (MoA). Human kallikrein 2 (KLK2) is a prostate-specific antigen expressed across the prostate cancer disease continuum. However, it was not recognized as a therapeutic target for prostate cancer in the past due to limited evidence of its cell surface expression. In this study, we systematically characterized KLK2 expression in prostate cancer, confirmed its cell surface expression, and demonstrated the preclinical efficacy of three KLK2-targeting therapeutics with distinct MoA.

EXPERIMENTAL DESIGN: The KLK2 expression profile in different stages of prostate cancer …

Educational Policies Committee Agenda November 6, 2025, Utah State University

Educational Policies Committee

• Approval of Minutes - October 2, 2025
• Subcommittee Reports
• Curriculum Subcommittee
• Academic Standards Subcommittee
• General Education Subcommittee
• Other Business
• Adjourn: 4:00 pm

Systematic Review Of Elementary Cybersecurity Education: Curriculum, Pedagogy, And Barriers, Na Liu, Siyu Long, Florence Martin

Journal of Cybersecurity Education, Research and Practice

Abstract -As children increasingly engage with digital platforms, the need for effective cybersecurity education has become urgent. This systematic review synthesizes 81 studies published between 2017 and 2024 to examine global curricula research focus and topics, pedagogical approaches and assessment methods, and key challenges in elementary cybersecurity education. The findings reveal six major thematic categories: student awareness, parental mediation, teacher engagement, curriculum design, community and policy support, and pedagogical innovation. Among instructional strategies, game-based learning and narrative storytelling emerge as the most frequently explored. Despite this growth, major gaps remain in curriculum consistency, teacher preparation, assessment rigor, and stakeholder coordination. …

The Impact Of Artificial Intelligence On Leadership: A Systematic Literature Review Of Emerging Aspects And Organizational Effectiveness, Adrian Graca

European Management Studies

Purpose: In today’s working environment, constant change has become the norm. Various departments are undergoing transformations from traditional systems to those more suitable for a technology-driven environment. This systematic literature review investigates the evolving landscape of leadership strategies in the context of artificial intelligence integration within organizations. Technological advancements necessitate a transformation in leadership approaches to harness AI's potential effectively while addressing associated challenges such as ethical concerns and human-machine collaboration.

Design/methodology/approach: This research is a systematic literature review conducted using the PRISMA framework. Relevant academic publications were sourced from reputable databases, including Web of Science, Scopus, and EBSCO. A …

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Chinese Women’S Rising Refusal Of The Family : The Problems, The Resistance, The Post-Family And Post-Capitalist Work Imaginaries, Peier Chen

Lingnan Theses (MPhil & PhD)

A new generation of Chinese women is questioning the family by examining internal contradictions in parent-child relationships, particularly in how intimacy and care are enacted, while also challenging the legitimacy of the family institution that underpins gendered divisions of labor and hierarchies. Some of them are revealing the problems within the family and refusing patriarchal marriage and family as their daily act of resistance. Their resistance extends beyond the family, into their workplaces, where gender division and hierarchies are also at work. This emerging phenomenon presses us to theorize today’s family problems, especially concerning those related to women’s gendered oppression, …

Roots Of Care, Wings Of Learning: Protecting And Prioritizing Wellbeing In Education, Rajni Shankar-Brown

National Youth Advocacy & Resilience Journal

No abstract provided.

Team Student: A Comprehensive Model For Family-Friendly, Student-Centered Middle Schooling, Gabrielle Brundidge

National Youth Advocacy & Resilience Journal

This article examines the implementation of a holistic, student-centered framework known as TEAM Student at Lee Roy Myers Middle School. Through intentional relationship-building, mentorship, family engagement, and targeted academic support, the school has increased student success and community involvement. The model’s effectiveness is demonstrated through improved behavioral and academic data, enhanced parent-school communication, and a strengthened school culture rooted in empathy and inclusion. This journal article focuses on the Home and Head Strands of NYAR’s goals.