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Fgf13 Regulates Vgsc-Independent Cardiomyocyte Impulse Propagation Via Cx43 Trafficking, Lala Tanmoy Das, Mattia Malvezzi, Aravind R Gade, Maiko Matsui, Margaret Mckay, Eric Q Wei, Matea J Zelich, Keon Mazdisnian, Jared Kushner, Bi-Xing Chen, Isabella Distefano, Daniel Roybal, Lin Yang, Lisa Stoll, James C Lo, Marian Kalocsay, Fadi G Akar, Steven O Marx, Geoffrey S Pitt Dec 2025

Fgf13 Regulates Vgsc-Independent Cardiomyocyte Impulse Propagation Via Cx43 Trafficking, Lala Tanmoy Das, Mattia Malvezzi, Aravind R Gade, Maiko Matsui, Margaret Mckay, Eric Q Wei, Matea J Zelich, Keon Mazdisnian, Jared Kushner, Bi-Xing Chen, Isabella Distefano, Daniel Roybal, Lin Yang, Lisa Stoll, James C Lo, Marian Kalocsay, Fadi G Akar, Steven O Marx, Geoffrey S Pitt

Faculty, Staff and Student Publications

Background: FHF (fibroblast growth factor homologous factor) variants associate with arrhythmias. Although FHFs are best characterized as regulators of voltage-gated sodium channel (VGSC) gating, recent studies suggest broader, non-VGSC-related functions, including regulation of Cx43 (connexin 43) gap junctions and hemichannels, mechanisms that have generally been understudied or disregarded.

Methods: We assessed cardiac conduction and cardiomyocyte action potentials in mice with constitutive cardiac-specific Fgf13 ablation (cFgf13KO) while targeting Cx43 gap junctions and hemichannels pharmacologically. We characterized FGF13 regulation of Cx43 abundance and subcellular distribution. With proximity labeling proteomics, we investigated novel candidate mechanisms underlying FGF13 regulation of Cx43. …


Iconic Voices And Ai: The Legal Battle Against Voice Cloning, Ezra Ashkenazi Dec 2025

Iconic Voices And Ai: The Legal Battle Against Voice Cloning, Ezra Ashkenazi

Cardozo Arts & Entertainment Law Journal (AELJ) Blog

In a recent interview with The Guardian, the legendary Hollywood actor, Morgan Freeman, expressed his distaste with AI’s use of his voice. Freeman went on to say, “I get paid for doing stuff like that, so if you’re gonna do it without me, you’re robbing me.” Freeman went further and said that his lawyers “[A]re already ‘very, very busy’ tackling unauthorized artificial intelligence uses of his voice.” While that is the last we have heard from Freeman and his legal team on the matter, this article will analyze the potential legal arguments one can bring to enjoin a company’s …


Heart-Centered Discernment In Leadership: Pope Francis’S Teachings In Dilexit Nos, Jessica Christie Ludescher Imanaka Dec 2025

Heart-Centered Discernment In Leadership: Pope Francis’S Teachings In Dilexit Nos, Jessica Christie Ludescher Imanaka

Journal of Management for Global Sustainability

This paper articulates the central teachings of Pope Francis’s final encyclical, Dilexit Nos, and explains how these teachings can guide business leadership. Dilexit Nos offers spiritual guidance “on the human and divine love of the Heart of Jesus Christ.” This spiritual encyclical concludes with a reminder about the importance of the love of Christ for the work to which the social encyclicals Laudato Si’ and Fratelli Tutti call us. Pope Leo XIV recently clarified the import of Dilexit Nos for our love for the poor in an apostolic exhortation, Dilexi Te, which Francis had been writing prior to his death. …


An Innovative Hdm Model For Assessing Renewable Heat Energy Resources In Utility Energy Systems, Mark Alan Ryan Dec 2025

An Innovative Hdm Model For Assessing Renewable Heat Energy Resources In Utility Energy Systems, Mark Alan Ryan

Dissertations and Theses

Renewable Heat Energy projects exhibit numerous unique, complex, and often conflicting characteristics, including varying project sizes, diverse energy resources, stakeholder demands, and significant challenges in energy conversion applications. Traditionally, cash flow analysis and return on investment are the most widely recognized metrics for evaluating remote energy projects. However, numerous quantitative and qualitative factors influence the overall performance and success of Renewable Heat Energy System (RHES) projects. A comprehensive approach using advanced tools is essential for assessing the factors and criteria that significantly impact these projects.

This research investigates the key quantitative and qualitative factors that contribute to the successful implementation …


The Power Of Positive Lesbian Representation In Television: How It Affects The Well-Being And Identity Formation Of Lgbtq+ Adults, Brittany Berry Dec 2025

The Power Of Positive Lesbian Representation In Television: How It Affects The Well-Being And Identity Formation Of Lgbtq+ Adults, Brittany Berry

University Honors Theses

To date, there are no studies which explore the effects that positively represented Black and lesbian characters in television have on LGBTQ viewers. Exposure to LGBTQ characters has the potential to validate LGBTQ identities and improve well-being. A comprehensive literature review and quantitative analysis using Żerebecki et. al.'s codebook reveals there are simply not enough characters depicted to provide such research. In an attempt to demonstrate the qualities possessed by positively portrayed Black, lesbian characters, this study analyses Taissa Turner from the hit series Yellowjackets available on the streaming network Paramount+.


Human Evil (In The Weird), Lucas Ethridge Dec 2025

Human Evil (In The Weird), Lucas Ethridge

University Honors Theses

This paper examines a trending doom in speculative fiction: the post-human age. Many modern works have started to look past human civilization as humans surrender all hope and faith in a climate-doomed world. Honing in on core concepts in Weird fiction, this paper explores human merit through Old and New Weird. A good part spends time establishing the canon, looking at similar patterns across age, philosophy, war and genre. The chief question asks if humankind was ever worth saving.


Synergistic Potential Of Sipuleucel-T In Enhancing Immunotherapy For Metastatic Castration-Resistant Prostate Cancer, Kavita Rawat, Varnika Punia, Parker Mathews, Sara Mccoy, Wilbur Song, Muhammad A Saeed, Russell K Pachynski Dec 2025

Synergistic Potential Of Sipuleucel-T In Enhancing Immunotherapy For Metastatic Castration-Resistant Prostate Cancer, Kavita Rawat, Varnika Punia, Parker Mathews, Sara Mccoy, Wilbur Song, Muhammad A Saeed, Russell K Pachynski

2020-Current year OA Pubs

Clinical trials of immunotherapy in metastatic castration-resistant prostate cancer (mCRPC) have largely been unsuccessful despite promising preclinical studies and proven efficacy in other solid tumors. These disappointing clinical outcomes have been attributed to an immunosuppressive tumor microenvironment, a relative lack of infiltrating immune effector cells, and tumor-related and host-related factors, which collectively render prostate cancer a relatively immunologically "cold" tumor. Sipuleucel-T (Provenge), an autologous cellular immunotherapy, induces an immune response targeted against prostatic acid phosphatase. It received approval from the US Food and Drug Administration in 2010, marking the first immunotherapy to show an overall survival benefit in patients with …


Chemical Profile Of Earthworm Flour With Kasgot Media Enriched With Cow Blood And Date Pulp, Ikrima Ahdavia, Imra Atun Helmi, Hidayati Nufus, Muhammad Farid, Ahmad Sjahriza Dec 2025

Chemical Profile Of Earthworm Flour With Kasgot Media Enriched With Cow Blood And Date Pulp, Ikrima Ahdavia, Imra Atun Helmi, Hidayati Nufus, Muhammad Farid, Ahmad Sjahriza

Chimica et Natura Acta

Fish meal is used as an ideal protein source for feed with a high level of digestibility but its limited and costly. This study explores earthworm flour as an alternative protein source, cultivated in kasgot (maggot residue) media enriched with organic waste. The novelty of this research lies in using maggot residue as the living medium for earthworms, enhancing the nutritional value of the earthworm flour, making it more beneficial and suitable as an additive protein feed ingredient. The kasgot medium was formulated by mixing boiled cow blood with date pulp fermented with EM4 probiotics in three different ratios: 2:1 …


School And District Leaders’ Understanding Of Technology Organizations’ Cyber Business Practices, Jayejaye Johnson Dec 2025

School And District Leaders’ Understanding Of Technology Organizations’ Cyber Business Practices, Jayejaye Johnson

Journal of Educational Research and Practice

Educational technology (EdTech) interoperability throughout cyberspace provides the financial opportunity to collect and sell student privacy information in digital learning environments, challenging school leaders to govern schools and keep children safe. School leaders provide the resources, funding, planning, decision making, and administration for EdTech cybersecurity practices and policies, yet little is known about what public school leaders understand. A quantitative study was designed using primary data collected from an online survey. Four research questions guided this study: What are the differences in cybersecurity practices and policy response scores (1) between male and female school leaders; (2) among leaders with different …


Child Assent Practices In Research: Improving Ethics, Decision-Making, And Inclusivity, David C. Coker, Ketaki Inamdar, Daniel F. Mccleary, Lesley Cottrell Dec 2025

Child Assent Practices In Research: Improving Ethics, Decision-Making, And Inclusivity, David C. Coker, Ketaki Inamdar, Daniel F. Mccleary, Lesley Cottrell

Journal of Educational Research and Practice

The following article addresses a conundrum: What if child assent in research were a fully informed, stand-alone process that empowered all children to discuss meaningfully, negotiate, and decide how and what the research experience would look like? Past research and practices suggest that child assent, when children (youths to 17-year-olds who have not been emancipated) agree to participate in research before, during, and after parents’ or guardians’ consent, is rife with problems that minimize informed participation and prize procedural ethics over true understanding of the processes and autonomous decision-making. Academic articles often lack details, as length requirements and brevity preclude …


Breaking The 'Emotional Woman' Stereotype: A Barrier To Women's Leadership, Mobina Amirsoleymani Dec 2025

Breaking The 'Emotional Woman' Stereotype: A Barrier To Women's Leadership, Mobina Amirsoleymani

Showcase of Scholars

No abstract provided.


Wired Differently, Not Broken, Abdullah Imran Dec 2025

Wired Differently, Not Broken, Abdullah Imran

Showcase of Scholars

No abstract provided.


How Racialized Language Sustains The “Illegal Hispanic” Stereotype, Amaya Arellano Dec 2025

How Racialized Language Sustains The “Illegal Hispanic” Stereotype, Amaya Arellano

Showcase of Scholars

No abstract provided.


Create @ State 2011, Arkansas State University - Jonesboro Dec 2025

Create @ State 2011, Arkansas State University - Jonesboro

Create@State

The proceedings book for 2011


Enhancing Archives And Records Management In Low-Resourced Organizations Through Experiential Learning, Jinfang Niu Dec 2025

Enhancing Archives And Records Management In Low-Resourced Organizations Through Experiential Learning, Jinfang Niu

Journal of Contemporary Archival Studies

Master’s students in Archives and Records Management could help low-resourced organizations address their Archives and Records Management needs while gaining practical experience. Archives and Records Management education programs could facilitate this mutually beneficial relationship by offering internships and service-learning courses. This paper analyzes the strengths and limitations of these two experiential learning mechanisms and discusses solutions to overcome the limitations. It argues that service-learning is especially suitable for addressing the Archives and Records Management needs of low-resourced organizations and proposes a service-learning model for that purpose.


Semiotics Of The Identity Of The Saudi National Day Slogan During The Reign Of King Salman Bin Abdulaziz, Norah Saad Mohammed Al-Shahrani Dec 2025

Semiotics Of The Identity Of The Saudi National Day Slogan During The Reign Of King Salman Bin Abdulaziz, Norah Saad Mohammed Al-Shahrani

UB Journal for Humanities

This research analyzes the semiotics of the visual identity of the Saudi National Day during the reign of King Salman bin Abdulaziz. It aims to analyze the semantic and value dimensions associated with Saudi society and its cultural and civilizational contextual components through the structural elements of the logo: the visual and iconic on the one hand, and the linguistic on the other. The investigation also measures the transformations and changes in the structure of the logo and its advertising production that have evolved over the past nine years. The research utilized semiotic analysis of the logo to explore the …


Restricted Word Order In Languages Without Overt Case Marking: Evidence From Modern Dialects Of Arabic, Mustafa Ahmed Al-Humari Dec 2025

Restricted Word Order In Languages Without Overt Case Marking: Evidence From Modern Dialects Of Arabic, Mustafa Ahmed Al-Humari

UB Journal for Humanities

The study examines the morphosyntactic strategies used in Arabic language to indicate grammatical functions (subject, object) within a sentence, comparing and contrasting modern dialects of Arabic, particularly Saudi Arabic, and Yemeni Arabic, with Standard Arabic. The empirical observation of the study is that, while Standard Arabic mainly relies on a case marking strategy to determine grammatical functions, the modern dialects of Arabic under investigation are incapable of employing this strategy. This incapability raises questions about how grammatical functions are indicated in the absence of overt case morphology in the mentioned dialects. The paper argues that the absence of overt case …


Legal Controls / Regulations For Advertising Financial Products And Services Which Are Provided By The Financial Institutions, Essa Ali M Aseery Dec 2025

Legal Controls / Regulations For Advertising Financial Products And Services Which Are Provided By The Financial Institutions, Essa Ali M Aseery

UB Journal for Humanities

Financial institutions offer multiple range of diverse services with the goal of supporting and advancing economic security, conducive to achieving benefits and profits given that hey use and utilize advertising and promotion as a means of delivering and communicating their services and products to individuals and society, to the effect that this necessitates their adherence to and compliance with legal systems and regulations related to advertising. Of importance, this requires the accuracy of the data and information it contains, the clarity and soundness of its language, the inclusion of all service and product data, the avoidance of misleading and deceptive …


The Interrelationship Between The Use Of The Applications Of The Forth Industrial Revolution, Governance And Combating Administrative Corruption, Abdul Wahab Shabab Al-Shamilan Dec 2025

The Interrelationship Between The Use Of The Applications Of The Forth Industrial Revolution, Governance And Combating Administrative Corruption, Abdul Wahab Shabab Al-Shamilan

UB Journal for Humanities

This study aimed at identifying the direct relationship between the usage of the fourth Industrial Revolution and the governance of administrative processes (including its five dimensions of transparency, accountability, justice, integrity and participation). The fieldwork was applied on a sample of 209 cases of the staff of the Industrial College of Jubail using a questionnaire, descriptive statistics and correlation analysis. The results indicated that there exist positive and significant relationships between the use of the applications of the fourth industrial revolution in the administration domain and combating administrative corruption.


The Traditional Howdah And The Installation Art In The Field Of Handcraft Artwork: A Proposed Conceptual Idea., Faten Mahmud Suleman Helal Dec 2025

The Traditional Howdah And The Installation Art In The Field Of Handcraft Artwork: A Proposed Conceptual Idea., Faten Mahmud Suleman Helal

UB Journal for Humanities

In Arab heritage and some countries of the world, the howdah is considered a societal tradition since ancient times, as it has been used for various purposes. The art installation is also considered one of the modern arts that rely on technological means, materials, and tools. Through this art and the types of traditional howdahs, the artist can create an artistic work that interacts. Scenes with him, Artists of a handcraft art works have expanded their thought, concept, and philosophy in creating the form of artistic work. The goal of the research is to develop a conceptual idea for an …


Fostering Oral English Skills Beyond Formal Learning In Saudi Efl Setting, Ghazwan Mohammed Saeed Mohammed Dec 2025

Fostering Oral English Skills Beyond Formal Learning In Saudi Efl Setting, Ghazwan Mohammed Saeed Mohammed

UB Journal for Humanities

The increasing research on informal language learning illustrates awareness about out-of-class learning. This study aimed to explore how technological advances are being used informally to enhance EFL learners’ oral skills. The study was conducted at the University of Bisha, Saudi Arabia. Employing a survey, data were collected from 191 learners at the university level. The participants were male and female students who were enrolled at different colleges of the university. Findings revealed that learners frequently use a set of strategies for out-of-class oral skills enhancement. The listening and speaking strategies were quite similar, which indicated that learners were aware of …


Program Book 2025, Kari Harris Dec 2025

Program Book 2025, Kari Harris

Arkansas Liberal Arts and Humanities Day

The program book for the inaugural Arkansas Liberal Arts and Humanities Day held on November 13th, 2025 in the Arkansas State Capitol building in Little Rock.


Propaganda And The Nature Of Militarism And Hatred, Silas Wilkinson Dec 2025

Propaganda And The Nature Of Militarism And Hatred, Silas Wilkinson

Arkansas Liberal Arts and Humanities Day

How is it that an entire generation was taught to hate? What causes an entire generation to blindly follow a regime? To want so badly to die for a cause that had long started splitting at the seams before the Second World War even started? These are questions that many have asked, but few are able to answer. I will be presenting my research exploring different examples of how propaganda was used by the Nazis as a weapon. It was a poison they carefully fed into impressionable minds. I will be exploring the power it held over an entire generation …


A-State Debate, Abigail G. Mock, Rocco Hicks, Samantha Hagler Dec 2025

A-State Debate, Abigail G. Mock, Rocco Hicks, Samantha Hagler

Arkansas Liberal Arts and Humanities Day

The A-State Speech and Debate team focuses on real world communication, argumentation, and persuasion skills. We compete in numerous competitions like Arkansas Student Congress, International Public Debate Association tournaments, and Forensic Championships. Our main focus is creating an inclusive environment for students to build skills applicable and necessary for fields like politics, education, law, psychology, and media. These skills include writing and delivering speeches, bill writing, critical thinking, scholarly research, conflict management, and much more. Overall, the students on the A-State Debate team are passionate about communication and its application in day to day life. These students work diligently to …


Ecology Of Subaerial Algae: Photosynthetic Capacity As A Function Of Relative Humidity In A Naturally- Occurring Association, James A. Nienow Dec 2025

Ecology Of Subaerial Algae: Photosynthetic Capacity As A Function Of Relative Humidity In A Naturally- Occurring Association, James A. Nienow

Georgia Journal of Science

Subaerial algae are defined by their ability to grow on surfaces exposed directly to the air. We are currently investigating the nature of the adaptations that allow these unicellular microorganisms to form rich growths in an environment subjected to repeated and prolonged periods without liquid water. It is well known from laboratory studies that at least some members of the group are able to sustain metabolic activity using water vapor at high relative humidity. However, data concerning the significance of this ability in natural populations are almost completely lacking. To help fill in this gap, we tracked the photosynthetic capacity …


The Public Duty Doctrine & State Governmental Tort Liability: A Brief History And A Solution For The Current Paradigm, Cooper Harrison Dec 2025

The Public Duty Doctrine & State Governmental Tort Liability: A Brief History And A Solution For The Current Paradigm, Cooper Harrison

University of Memphis Law Review

In the early morning hours of Friday, September 2, 2022, a young woman named Eliza Fletcher was jogging down Central Avenue in Memphis, Tennessee when a man violently abducted her.2 Shortly after the abduction, the Memphis Police Department issued a city-wide watch for Mrs. Fletcher, volunteers searched wooded areas around town, and news outlets broadcasted the few known details of her abduction.3 Mrs. Fletcher disappeared near the University of Memphis Campus just a few hundred feet from a local private school, providing police with a cache of surveillance footage that helped them quickly pinpoint a suspect.4 On September 3, just …


Empowering The People Of The Developing World Dec 2025

Empowering The People Of The Developing World

Vision and mission statements

No abstract provided.


September 26, 2025, Marra L. Piazza Brass Dec 2025

September 26, 2025, Marra L. Piazza Brass

Philomathean

No abstract provided.


Dementia Unearthed, Kathy Fuller Guisewite Dec 2025

Dementia Unearthed, Kathy Fuller Guisewite

Philomathean

No abstract provided.


Whence I Came, Karl Mel Korn Dec 2025

Whence I Came, Karl Mel Korn

Philomathean

No abstract provided.