Digital Commons Network^™

A Genetic Interaction Between Ded1 And Hat1 In Saccharomyces Cerevisiae Reveals A Role For Hat1p In Cytoplasmic Rna Granule Accumulation, Audrey J. Panko, Aidan Winters, Nicholas R. Rothbard, Angela K. Hilliker

Biology Faculty Publications

Ded1p is an essential translation initiation factor that interacts with and is modulated by eIF4F. Ded1p also promotes the assembly and disassembly of stress granules, which contain nontranslating mRNAs and translation initiation factors. As Ded1p affects both mRNA storage and translation initiation, regulation of Ded1p's function may affect whether mRNAs are translated or localized to cytoplasmic RNA granules. To identify regulators of Ded1p in Saccharomyces cerevisiae, we screened for overexpression suppressors of the severe growth defect conferred by high levels of Ded1p. We found that overexpression of HAT1, a lysine acetyltransferase, can suppress the growth defect conferred by …

The Bmt: Will This Time Be Different?: Red Hook Braces For A Mega-Project On The Waterfront. Can It Avoid The Mistakes Of Atlantic Yards?, Steve Kastenbaum

Capstones

"The BMT: Will this time be different?" investigates how New York City's push to rapidly build housing is reshaping communities. A $3.5 billion mega-project at the Brooklyn Marine Terminal promises transformation through 6,000 apartments, a modernized port, and waterfront improvements, but residents are split on whether it represents progress or displacement. The development uses a controversial "general project plan" process that bypasses normal community review, the same approach that enabled the still-unfinished Atlantic Yards project. Local voices in Red Hook range from excitement about investment, jobs and amenities to fears about gentrification and broken promises. This pilot episode launches a …

The Debate Over The Lebanese Diaspora’S Vote: As Lebanon Tries To Reform Itself, The Diaspora Wants A Say At The Ballot Box, Sandra Sadek

Capstones

The Lebanese diaspora is demanding full voting rights ahead of the 2026 parliamentary elections. The movement comes at a time when the 2026 parliamentary elections coincide with a moment of national reckoning. Despite urgency from a vocal diaspora and pressure from several members of parliament and the cabinet, the bill to permanently amend the current electoral law has stalled on the speaker’s desk. The outcome of that struggle stands not only to determine how much influence this global constituency can have on Lebanon’s future but also what the country’s recovery path can look like amid a dramatically changing regional landscape. …

Regulation Of Chromatin Remodeling By The Post-Hsa Domain Of Brg1, A Subunit The Baf Atp-Dependent Chromatin Remodeling Complex, Min Sze Ewe

Theses & Dissertations

The ATP-dependent chromatin remodeler BAF complex regulates nucleosome positioning, chromatin accessibility, and tissue specific gene expression. Its catalytic subunit, BRG1, contains several regulatory domains including the post-HSA region, proposed to modulate ATPase activity. Multiple cancer-associated mutations map to these regulatory regions underscoring their importance, yet the precise role of the post-HSA region in chromatin remodeling remains poorly understood.

To investigate the function of the post-HSA domain, we ectopically expressed FLAG-tagged BRG1 with post-HSA deletion (Δpost-HSA BRG1) in mouse embryonic stem cells. Western blot analysis confirmed expression of the mutant protein. To determine the effects of mutant protein expression on chromatin …

Advancing Point-Of-Care Healthcare Diagnostics To Tackle Future Outbreaks And Pandemics: Nanotechnology-Driven Developments And Impact On Rapid Pathogen Detection, Naresh Mandal, Bidhan Pramanick, Tarun Kanti Bhattacharyya, Baljit Singh

Research Outputs: 2025-Present

No abstract provided.

Ice In Nyc, Student Interfaith Walkout, And Bronx Night Market Bid Farwell: Reporting For Newmark’S “Audio Files”, Rebecca Raghunath

Capstones

Audiofiles is a news magazine podcast powered by students at CUNY’s Craig Newmark Graduate School of Journalism. Students produce stories that seek to explore and explain the core issues defining the lives of New Yorkers through in-depth reporting, hosting interviews, and personal narratives. This capstone includes a collection of news stories that address immigration, politics, and food tourism. The first feature is about the chilling effect ICE enforcement has had on immigrant owned businesses in East Harlem. The second feature focuses on pro-Palestinian protests on college campuses. This story examines how a student walkout at an interfaith workshop led to …

The American Eye And Greek Music: How Greek Artists Are Changing To Become Palatable To The Non-Greek Listener, Andriana Kourkoumelis

Capstones

International artists are trying to successfully bridge into the U.S. music industry, and Greek pop singers are finally making a dent. This year, some of the biggest names in Greece, along with a couple new faces, were working with their labels to rebrand as a means to connect with the American listener and expand their listenership. With three notable tours happening across the states from muscians like Konstantinos Argiros, Anastasia, and Marina Satti playing venues like the Barclays Center and Sony Hall, it's safe to assume that there is a shift happening in the world of Balkan and Hellenic entertainment. …

The Next Drug Epidemic Is Legal: The Nation's Kratom Problem Is More Complicated—And More Harmful—Than It Seems, Elizabeth Walsh

Capstones

This two-part health and science investigative piece reports how kratom and its offshoots have quietly fueled a lucrative and legal addiction epidemic for the last decade. While kratom’s derivative alkaloid 7-hyrdoxymitragynine made headlines this year and as the DEA is poised to ban the strong derivative, “natural” kratom and other kratom-derived products will remain. This piece tracks the history of the 'gas‑station opioid' crisis in the U.S. over ten years: what was thought to be an innocuous southeast Asian supplement has become multi-billion dollar industry built on gray‑area laws, marketed falsehoods, and regulatory loophooles.

Part 1: The ‘Gas Station Opioid’ …

Two Major Ontario Hospital Labs Bought Research Dogs From U.S. Breeder With Troubled Pastdogs Bred For Scientific And Medical Testing Suffer Abuse As The Scientific Industry Increasingly Turns To Alternatives For Research., Allison Hunter, Mary Beech, Sami Marshak, Kate Morano

Capstones

The purpose-bred dog breeding industry for research is little known. Each year, thousands of dogs are bred for scientific and medical testing, supplied to research facilities by a handful of major commercial breeders. But gaps in enforcement and regulation have allowed abuses to persist, even as the industry increasingly turns to alternatives to animal testing. Animal rights advocates have been decrying the treatment of these dogs. A federal Inspector General report found lax oversight of the industry, raising further concerns about how dogs are treated. This story was reported in collaboration with the Investigative Journalism Bureau, based in Toronto, and …

Artificial Intelligence And Consumer Trust, Privacy, And Protection On Digital Platforms, Alheri Gajere Adams

Walden Dissertations and Doctoral Studies

Academic scholars have researched the impact of artificial intelligence (AI) on privacy, trust, and data governance; however, substantial gaps remain—particularly regarding how AI influences consumer trust and privacy among Texas consumers subscribed to digital platforms. The purpose of this generic qualitative study was to explore how Texas consumers experience and perceive online platforms for personal and private use regarding online data privacy and trust, underscoring the gap in prior research on how state-level consumer protection laws, such as the Texas Deceptive Trade Practices Act (DTPA), address concerns relative to data trust, privacy, and digital protection. The conceptual framework that guided …

The Effect Of Wearable Resistance Microloading On Sprint Biomechanics, Curtis King

Doctorate in Kinesiology

Wearable resistance refers to the practice of attaching weight to specific body segments during sport-specific movements. This study investigates the impact of progressive microloading training, which involves wearing wearable resistance on the torso (3%, 5%, 10%), on sprint mechanics and performance among competitive athletes. A total of twenty-two participants engaged in a nine-week study that included both progressed and non-progressed group protocols. Sprint times, hip angles, and perceived fatigue were monitored at pre, mid, and post-intervention. A manual biomechanical analysis combined with SPSS-based repeated measures ANOVA indicated no statistically significant changes in hip angle or sprint times between the groups. …

Strength And Conditioning As An Injury Prevention Strategy In College Baseball, Elizabeth Record

Doctorate in Kinesiology

Shoulder injuries are common and often result in impairments, particularly among baseball players. The clinical management of shoulder injuries is of interest to a wide-ranging audience within the sports medicine community. This dissertation aimed to investigate the effects of a strength and conditioning program on injury prevention in college-aged baseball players, hypothesizing that a comprehensive strength and conditioning program implemented before the start of the season would prevent shoulder injuries in baseball players over the course of one spring season at the collegiate level of baseball. Four participants completed a four-week strength and conditioning program before the start of their …

(Un)Intended Consequences Of Race In Medicine: The Ethics Of Race-Based Medical Practice And The Perpetuation Of Structural Racism, Allegra Merriweather

Electronic Theses and Dissertations

This dissertation proposes that race-based medicine acts as a form of structural racism that is ethically indefensible. While it may be claimed to be a neutral diagnostic tool, the medical use of race as a biological proxy only further enforces the very hierarchies it purports to remediate, reinscribing inequity from conception to death. Building off Jacques Ellul’s work on Technique, we interpret race-based medicine as a self-perpetuating system that values procedural expediency over moral accountability. In nine chapters, the analysis follows the ways this technique is manifested in genetics and assisted reproduction, where commodified racial selection preserves social hierarchies; in …

Accepting Vs Understanding, Transgender Aliens And Alienation, Reyna G. Aliah

English

Trans people have been the subject of intense discrimination in recent years, suffering dehumanization from right-wing and conservative groups. This dehumanization (and the fear resulting from it) parallels common attitudes in science fiction about actual aliens. Orson Scott Card’s Hierarchy of Foreignness classifies individuals and species into five categories, depending on their sentience; whether they are from the same city, nation, or planet; and whether communication is possible. This paper examines how transgender people can be classified according to this system on a societal level, with said class depending on the lens used to view them as well as the …

Playing By Feel: Gender, Emotion, And Social Norms In Overwatch Role Choice, Cristo Leon, Angela Arroyo, James Lipuma

STEM for Success Resources

This paper explores how emotion, gameplay context, and social norms shape role choice in both digital and institutional systems. Using Overwatch as a case study, it examines gendered experiences of physiological excitement and decision-making during play. Women often describe heightened emotional engagement where victory represents both personal achievement and resistance to cultural expectations. Such emotions influence situational choices, including whether to play as a Tank, DPS, or Support, and which hero to select based on perceived risk or visibility. Drawing on feminist game studies and transdisciplinary communication, the authors argue that role preference is determined not only by game mechanics …

Assessment Of Polymeric Chloroquine Formulations For Targeted Therapy Of Ulcerative Colitis And Metastatic Colorectal Cancer, Neha Kumari

Theses & Dissertations

Effective targeted drug delivery is a critical unmet need in the management of both ulcerative colitis and metastatic colorectal cancer, where conventional systemic therapies may be hindered by suboptimal efficacy and significant side effects. This thesis explores the development and preclinical assessment of polymeric chloroquine (PCQ)-based nanotherapeutics, leveraging stimuli-responsive designs for disease-specific delivery and action.

For ulcerative colitis, a reactive oxygen species (ROS)-responsive nanogel system was engineered to release PCQ, a macromolecular derivative of hydroxychloroquine, specifically in the inflamed areas within the colon. Nanogels with well-defined size and positive surface charge were synthesized via reversible fragmentation chain transfer (RAFT) polymerization …

Investigating Metabolic Heterogeneity In Engineered Isogenic Microorganisms, Xinyue Mu

McKelvey School of Engineering Graduate Student Theses & Dissertations

Engineered microorganisms play an increasingly important role in the sustainable production of fuels, bioplastics, and other valuable biomaterials. Successful industrial deployment depends on maximizing product titers and ensuring process robustness at large scale. However, one of the major obstacles is non-genetic cell-to-cell heterogeneity arising from stochastic intracellular processes. Such heterogeneity can result in subpopulations that divert substrates toward growth rather than product biosynthesis, ultimately reducing yield and contributing to batch-to-batch inconsistency. To better understand the mechanisms by which cell-to-cell variation emerges, propagates, and impacts bioproduction, this dissertation investigated how intracellular energetic dynamics and stochastic biosynthetic noise contributed to metabolic heterogeneity …

A Framework For Fostering Flood Ready Neighborhoods, Kirsten Howard, Lucy Perkins, Alyson Eberhardt, Lisa Wise, Abigail Lyon, Lynn Vaccaro, Gracie Ballou, Annie Cox, Kate O'Brien

UNH Cooperative Extension

This resource summarizes lessons learned from the Flood Ready Neighborhoods Program and shares prompts and resources for readers related to community engagement and resilience building.

The Nursing Human Capital Value Model, Olga Yakusheva, Kathryn A. Lee, Marianne Weiss

Individual Articles

Nursing's economic value is presently framed within the dominant “outcomes-over-cost” value framework. Within this context, organizations employing nurses often use nursing budget reductions as a cost-minimization strategy, with the intent of retaining high quality outcomes. However, persistent issues such as nurse understaffing, burnout, and turnover threaten healthcare systems' capacity to deliver the quality, equitable, affordable patient care that the public requires. In this paper, we propose a new conceptual model and definition of nursing's economic value. The model development is guided by the convergence of three classic economic frameworks:human capital theory, production theory, and value theory. Grounded in these theories, …

Exploring The Medicinal Properties Of Indigenous Plants Within An Enabling Program: Bridging The Gap Between School, Aboriginal And Torres Strait Islander Knowledge And Science, Sharon L. Gough, Julie Sartori, Angela Jones

Research outputs 2022 to 2026

In 2021, less than half of Australian universities considered Indigenous perspectives in curriculum development, with only 15% ensuring Indigenous content in all courses. Literature acknowledges that a strengths-based approach to the inclusion of Aboriginal and Torres Strait Islander knowledge and perspectives, enhances representation and decolonises curriculum. In 2020, Noongar elder Vivienne Hansen, and John Horsfall created Noongar Bush Medicine, detailing the medicinal use of Indigenous plants. Yeshi, Turpin, Jamtsho, and Wangchuk noted that many Aboriginal and Torres Strait Islander communities use native plants for health purposes. However, there is limited data on the therapeutic efficacy of these plants. In 2024, …

El Último Viaje, Gaspar Pedro González

Maya America: Journal of Essays, Commentary, and Analysis

Gaspar le hizo una oferta a la revista: publicar uno de los capítulos de su último libro, Hojas de Onoño. El capítulo, titulado El Último Viaje, narra el último viaje de un anciano a la comunidad de su juventud, ubicada en el departamento de Huehuetenango, Guatemala. De forma lírica y metafórica, el autor describe cómo se desvanecen los recuerdos y la tristeza por las personas que ya no están. El poeta Daniel Caño escribió una breve reacción personal a la historia que incluimos al final de esta.

A Fish & A Bird, Deanna Moorehead

Theses

As a curtain of trees opens and dawn breaks over the glistening waters of Lake Ontario, a fish and a bird spot each other through the surface and fall madly in love. They dance and sing together from their respective atmospheres, yet each time the bird soars past the water's edge and onto the beach, the fish cannot follow. Night after night, by the light of the moon, the fish trains herself to leap out of the water, hoping to breach high enough to join her beau above. Late one afternoon, the fish approaches the shore, where the bird stands …

A System And Method For Validating Payee Identity In Unified Payments Interface (Upi) Based Payment Transactions, Alok Roy

Defensive Publications Series

The present disclosure relates to a system and method for validating payee identity in unified payments interface (UPI) based payment transactions. The method prevents misrouted payments in a digital payment environment, specifically addresses risks associated with mobile number reassignment. The system includes a mobile number re-authentication module designed to detect re-linking of mobile numbers to new accounts and an identity-change ledger that records historical mappings of mobile numbers to account holder identities. The method initiates by receiving a mobile number entry from a payor, performing a validation step that cross-references the entered number against the identity-change ledger, and generating a …

Graphical Display Of A Career In Chronological Order With Achievement Percentiles, Safwan Samla

Defensive Publications Series

A digital representation of a person’s career is provided in a manner that is easy to follow and provides important statistics relating to achievement assessments relative to others. A person’s career can be displayed through a graphical user interface comprising an X and Y plot wherein the X-axis comprises a timeline determined by a person’s career and the Y-axis comprises data-based categories pertaining to different achievement and experiences from the person’s career.

Book Review, Nathan Mishael O. Go

Budhi: A Journal of Ideas and Culture

Book review of "Humankind: A Hopeful History" by Rutger Bregman

The Aesthetics Of Endings, Mary Imbong

Budhi: A Journal of Ideas and Culture

What does it mean for an experience to end? Guided by this question, I offer an interpretation of John Dewey’s notion of endings in Art as Experience and propose a perspective on the role of endings in aesthetic experiences. We often instinctively view endings as the final note in a sequence of events—disconnected from the moments that come before it. Dewey, however, sees them not as an isolated fragment but as part of the unity of an experience. His themes of doing and undergoing, as well as unity and wholeness, challenge conventional views of experience and encourage reflection on how …

Central Bank Crisis Interventions: A Review Of The Recent Literature On Potential Costs, Patrick Aldridge, David A. Cimon, Rishi Vala

Journal of Financial Crises

Central banks may engage in large-scale lending and asset purchases to stabilize financial markets and implement monetary policy during crises. The ability of these actions to restore financial market functioning is well documented; however, they come with costs. We provide a literature review of the costs associated with these post-Global Financial Crisis central bank actions, without commenting on the net benefits they provide. We find support for the premise that crisis actions may negatively impact market liquidity, distort asset prices, increase rent-seeking and inefficient uses of the liquidity provided by the central bank, create international spillovers, and create distortions in …

Understanding Generation Z Polarization: Findings From A Preliminary Replication Study, Liane Weintraub

The Scholarship Without Borders Journal

Amid rising polarization and declining trust in democratic institutions, Generation Z (Gen Z) faces unique challenges in navigating civic discourse. This study presents comparative findings from two survey cohorts (2023, n = 56; 2025, n = 25) examining Gen Z students’ political identity, discourse habits, interpersonal trust, and civic attitudes. Framed by Social Identity Theory (SIT), Cultural Intelligence (CQ), and discourse theory, the study explores how ideological difference and identity signaling shape students’ willingness to engage across divides. Findings indicate continuity in partisan skepticism and discourse openness, but also growing fatigue, reduced trust, and ambivalence toward equity. While affective polarization …

Marooned: A Western Frontier Dismal Swamp Narrative, Professor Meya E. Hargett

The Scholarship Without Borders Journal

Marooned: A Western Frontier Dismal Swamp Narrative centers the erased figure of Samuel Mars, a lost Black station master whose movements through the Great Dismal Swamp have been excluded from dominant Underground Railroad cartographies. Here, the term “Marooned” refers not to abandonment, but to the maroon geographies of Black and Indigenous resistance encoded in land, lineage, and fugitive infrastructure.

Guided by Diasporic Maroon Memory Theory, Lineage as Method, and the Maroon Geographies Framework, this research reconstructs Mars’s trajectory through oral testimony, spatial patterning, and ancestral land memory. Rather than casting the Dismal Swamp merely as a site of refuge, this …

Article Title: Deconstructing Power And Gender: A Foucauldian Discourse Analysis Of Biopolitics, Necropolitics, And Sexual Scripts In Feminicide In Puerto Rico., Migdalia Marrero-Lafontaine

The Scholarship Without Borders Journal

Feminicide and gender violence cases in the last several decades in Puerto Rico have continuously increased, suggesting that this problem becomes worse as time passes. This study, therefore, focuses on identifying actionable insights that paint a picture of the impact it has on women over the age of 18 in Puerto Rico. In order to achieve this objective, the study relies on a strong theoretical framework that is made up of Foucauldian discourse analysis, necropolitics, and sexual scripts theories. One of the core findings of this research is that Puerto Rico’s colonial history and cultural norms sustain a cycle of …