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Image-Derived 3d Hepatic Lobule Modeling Of Acetaminophen-Induced Hepatotoxicity, Rebecca Lauren Strauss Jan 2026

Image-Derived 3d Hepatic Lobule Modeling Of Acetaminophen-Induced Hepatotoxicity, Rebecca Lauren Strauss

Selected Full-Text Master Theses 2021-

The liver’s highly structured vascular microarchitecture governs blood perfusion, metabolic zonation, and the spatial distribution of xenobiotic toxicity. Current computational models of hepatic drug metabolism often oversimplify this geometry, limiting their ability to capture realistic flow dynamics and cellular injury patterns. This study develops a multiscale computational framework to predict acetaminophen-induced hepatotoxicity using image-derived, three-dimensional hepatic lobule geometries. The model integrates computational fluid dynamics (CFD) with a mechanistic cellular injury module to simulate the interplay between perfusion, metabolism, and hepatocellular viability.

Realistic vascular reconstruction was achieved from histopathology liver slices, and the resulting geometry was meshed and solved using ANSYS …


Impact Of Social Media On Self Esteem And Body Image, Sunayana Sri Acharya Goribidnur Sudheendra Jan 2026

Impact Of Social Media On Self Esteem And Body Image, Sunayana Sri Acharya Goribidnur Sudheendra

Selected Full-Text Master Theses 2021-

This study examined how idealized self-presentation on social media relates to self-esteem and body image in young adults, and whether body dissatisfaction, general distress, or symptoms of depression, anxiety, and stress help explain that relationship. Ninety-eight undergraduate students from two universities completed an online survey measuring idealized online self-presentation (Presentation of Online Self Scale), self-esteem (Rosenberg Self-Esteem Scale), body esteem (Body Esteem Scale for Adolescents and Adults), general distress (Distress Questionnaire-5), and depression, anxiety, and stress symptoms (DASS-21). Contrary to expectations, greater idealized self-presentation was associated with higher, not lower, self-esteem. Idealized self-presentation was not significantly related to body esteem, …


Experiences Of Marginalization At The Intersection Of Race, Ethnicity, And Disability In Higher Education, Nora L. Portillo Jan 2026

Experiences Of Marginalization At The Intersection Of Race, Ethnicity, And Disability In Higher Education, Nora L. Portillo

Theses, Dissertations and Culminating Projects

Black and Latine college students with disabilities navigate higher education at the intersection of racism and ableism, yet their experiences remain underexamined. Autism and ADHD are particularly underrepresented in research and public discourse; moreover, unlike other disability categories in which students of color are overrepresented, Black and Latine children are less likely than white children to be accurately identified, and both disabilities are often framed around white prototypes. Guided by Disability Critical Race Theory, the present exploratory qualitative study used semi-structured interviews with ten undergraduates identifying as Black and/or Latine and with ADHD and/or on the autism spectrum attending a …


On Shaky Ground: America’S Public Lands Face An Uncertain Future, John Leshy Jan 2026

On Shaky Ground: America’S Public Lands Face An Uncertain Future, John Leshy

Colorado Environmental Law Journal

No abstract provided.


People Over Paper: The Effectiveness Of International Agreements Under Treaty Capture, Eric Nicholson Jan 2026

People Over Paper: The Effectiveness Of International Agreements Under Treaty Capture, Eric Nicholson

Colorado Environmental Law Journal

No abstract provided.


Peak Bagging: The Land Acquisition History And Public Access Rights That Make It Mostly Possible, Andrea Shipton Jan 2026

Peak Bagging: The Land Acquisition History And Public Access Rights That Make It Mostly Possible, Andrea Shipton

Colorado Environmental Law Journal

No abstract provided.


Holding The District Together With Duct Tape And Determiniation: A Study Of Superintendent Stress, Robert Orion Thompson Jan 2026

Holding The District Together With Duct Tape And Determiniation: A Study Of Superintendent Stress, Robert Orion Thompson

Dissertations and Theses

Researchers’ work found the superintendent role was increasingly complex. Superintendents experienced elevated stress, burnout, and turnover. However, the ways in which district context and coping strategies interacted to shape superintendent well-being remain insufficiently understood, particularly in rural settings. This study examined how school superintendents perceived and experienced occupational stress, the impact of that stress on their well-being and leadership, and the coping strategies they used. Notably, there was a focus on district size differentiation. Using a qualitative research design, data were collected through two focus groups in the western side of a rural state with superintendents representing districts with large …


Covid-19 Pandemic-Induced Social Isolation: A Hermeneutic Phenomenological Exploration Of Age And Time, Renee Reedy Jan 2026

Covid-19 Pandemic-Induced Social Isolation: A Hermeneutic Phenomenological Exploration Of Age And Time, Renee Reedy

Dissertations and Theses

Lockdown measures during the COVID-19 pandemic fundamentally altered social functioning, creating an urgent need to understand the lived experience of isolation across life stages. This qualitative hermeneutic phenomenological study explored how age and time shaped social isolation during the pandemic. Sixteen participants from three-generation households—adolescents (n=5), adults (n=6), and older adults (n=5)—were interviewed approximately five years post-isolation. Recruitment occurred through ResearchMatch, and interviews were conducted between February and March 2025. Participants represented diverse racial, ethnic, and geographic backgrounds, with isolation periods ranging from 27 to 426 consecutive days (¯x = 165 ± 124 days). Data analysis followed Gadamer’s hermeneutic circle …


Helpful Autism School-Based Services: Perspectives From The People That Received Services, Michael Angelo Grizzaffi Jan 2026

Helpful Autism School-Based Services: Perspectives From The People That Received Services, Michael Angelo Grizzaffi

Dissertations and Theses

Transitioning high school students with autism, primarily with a level 1 diagnosis, from high school to independence in young adulthood has evidence-based practices. However, preferences of the students who are receiving services had not been considered before. This study reviews the thoughts of what prior high school students find helpful in the services they receive. Choosing individualized evidence-based practices is ideal for students. Prior high school students' experiences demonstrate the desire for more transition skills teaching. Leading special educators in the skills of some evidence-based practices is required for the individualization of these practices the students need to occur. Leading …


Large Language Model Communication And Data Transfer Across A Simulated Telephone Line, Jared Reyes Jan 2026

Large Language Model Communication And Data Transfer Across A Simulated Telephone Line, Jared Reyes

Dissertations and Theses

This thesis presents a proof-of-concept communication system in which two local large language model endpoints communicate across a simulated analog telephone line using legacy USB modems. The project combines modem voice mode, modem data mode, local speech processing, and structured machine messaging into a single staged session. During the voice phase, one endpoint places a call, the other answers, speech generated by a locally hosted LLaMA-family model is synthesized with Piper, transmitted through the modem voice path, captured on the remote side, and transcribed with Faster-Whisper to drive the next response. After the voice exchange, the system transitions to a …


The Rhetoric And Memory Of Kumeprɛko, Benedicta Harford Jan 2026

The Rhetoric And Memory Of Kumeprɛko, Benedicta Harford

Dissertations and Theses

This thesis examines the rhetoric of Kume Prɛko and asks what its major rhetorical appeals were both during 1994 and afterwards. First, I analyze major images and a speech from the protest and identify how it framed the VAT tax as an embodied, urgent issue for all citizens to resist. Then, I consider how Akufo-Addo silenced this "vernacular" memory in favor of his "official" narrative, drawing off the work of John Bodnar. Ultimately, this thesis shows how difficult it is for those in power to remember grassroots dissent in all their complexity but also how hard it is to completely …


What Happens When We Face The Harm? Reflections On Restorative Justice, Conflict, And Accountability (And A Flyer On Practical Steps), Renate Alant Jan 2026

What Happens When We Face The Harm? Reflections On Restorative Justice, Conflict, And Accountability (And A Flyer On Practical Steps), Renate Alant

A with Honors Projects

This project explores conflict resolution, restorative justice, and meaningful apologies through reflections on Dr. Mikhail Lyubansky’s workshops hosted by the Psi Beta club at Parkland College. The paper examines how restorative justice focuses on accountability and repair rather than punishment, while the accompanying flyer encourages students to learn practical conflict resolution skills.


A Mixed Methods Study On Mexican American Satisfaction And Perception Of Clinical Trials, Grace Manzo Jan 2026

A Mixed Methods Study On Mexican American Satisfaction And Perception Of Clinical Trials, Grace Manzo

Dissertations and Theses

In the United States, the Food and Drug Administration sets expectations on the collection and reporting of race and ethnicity data. Ethnic data for Mexican Americans is often reported as “Hispanic or Latino.” Mexican Americans make up a significant percentage of “Hispanic or Latinos,” however, they remain significantly underrepresented in clinical trials. Grounded in Expectation-Disconfirmation Theory (EDT) and Social Cognitive Theory (SCT), this mixed-methods study investigates the relationship between satisfaction and perception of Mexican Americans who have participated in an ophthalmology clinical trial. This research aimed to understand the relationships among satisfaction with the clinical trial process, patient-reported outcomes, and …


Understanding The Role Of School Resource Officers In Addressing Students’ Mental Health Needs: A Phenomenological Study, Ryan Christopher Vinzant Jan 2026

Understanding The Role Of School Resource Officers In Addressing Students’ Mental Health Needs: A Phenomenological Study, Ryan Christopher Vinzant

Dissertations and Theses

Since the 1990s School Resource Officers (SROs) have been commonly employed in schools throughout the United States. However, their jobs may look very different depending on what setting they are in and the different administrative policies governing their work. Throughout this time, researchers have focused on the different roles that SROs have within the educational environment and how these roles are put into action when interacting with students. However, there have been limited studies exploring the role SROs play when interacting with students who are experiencing mental health problems or experiencing a mental health crisis. Mental health problems have become …


The Road To Winning This Battle: A Corpus Informed Exploration Of Metaphor In The National Addresses Of Leo Varadkar And Micheál Martin During The Covid-19 Pandemic (2020–2022), Caoimhe Power Gallagher Jan 2026

The Road To Winning This Battle: A Corpus Informed Exploration Of Metaphor In The National Addresses Of Leo Varadkar And Micheál Martin During The Covid-19 Pandemic (2020–2022), Caoimhe Power Gallagher

Irish Journal of Applied Social Studies

The first case of the novel Covid-19 virus reached the island of Ireland in February 2020. The nation-focused response was one of the most striking characteristics that most countries shared throughout the pandemic. Corpus-linguistic research on Covid-19 communication is reasonably well established across various contexts. However, it is under researched in Ireland. Building trust and a successful national response is very much dependent on how heads of government confront health emergencies through public communications. Political leaders across the world often use metaphors in their speeches to strategically control their audiences’ perceptions of various topics. Throughout the Covid-19 pandemic, Deputy Leo …


Navigating Relationships In Social Care Practice: Student Experiences On Placement In Ireland., Louise Mcanarney Mrs, Geraldine Fay Ms. Jan 2026

Navigating Relationships In Social Care Practice: Student Experiences On Placement In Ireland., Louise Mcanarney Mrs, Geraldine Fay Ms.

Irish Journal of Applied Social Studies

The professionalisation of social care in Ireland has reshaped the sector for workers, educators and students. With the advent of CORU regulation, social care education and practice has changed dramatically, necessitating a focus on the evolution of relational processes.

Quality relationships are the cornerstone of effective social care practice and form the basis for developing other essential skills (Morrison, 2015; McSweeney & Williams, 2018; Kaushik et al., 2023).  This concept is firmly embedded within the Standards of Proficiency for Social Care Workers as set out by the Social Care Workers Registration Board (SCWRB). Considering the significance of interpersonal dynamics; education …


Exploring The Psychological And Emotional Impact Of Race-Based Traumatic Stress (Rbts) Among The Black Irish Community, Diekololaoluwa Amujo, Sharon Lambert Dr Jan 2026

Exploring The Psychological And Emotional Impact Of Race-Based Traumatic Stress (Rbts) Among The Black Irish Community, Diekololaoluwa Amujo, Sharon Lambert Dr

Irish Journal of Applied Social Studies

Research indicates that racialised minorities may experience psychological distress and trauma as a result of racism and racial discrimination. Race-Based Traumatic Stress (RBTS) describes the psychological injury that can arise from repeated racial harm and has been linked to mental health disparities among racially minoritised groups. This qualitative study explores how Black Irish individuals experience and make sense of racism, and how racial distress is sustained over time within the Irish context.

Semi-structured interviews were conducted with 11 Black Irish participants who had experienced racism and sought psychological support. Data were analysed using reflexive Thematic Analysis (Braun & Clarke, 2021). …


The Path To Information Literacy: From Finding A Topic To Writing An Annotated Bibliography, Robyn Hartman, Claire Nickerson, Heather P. Vandyne Jan 2026

The Path To Information Literacy: From Finding A Topic To Writing An Annotated Bibliography, Robyn Hartman, Claire Nickerson, Heather P. Vandyne

All Open Educational Resources

This book is an adaptation of Ohio State University's Choosing & Using Sources: A Guide to Academic Research. It has been revised with a new introduction and learning objectives and section summaries. It also includes sections on common research assignments such as research plans, research logs, note-taking, and annotated bibliographies. The sections on evaluating resources have been expanded to include lateral reading with SIFT (Stop, Investigate the source, Find better coverage, Trace sources) and evaluation with CRAAP (Currency, Relevance, Authority, Accuracy, Purpose), the 5Ws (Who What When Where Why), and BEAM (Background, Exhibit, Argument, Method). Sections on generative AI have …


Attitudes Toward Dementia Among Nursing Students: A Cross-Sectional Study, Ngoc Ha Vo Thi, Thuy Nga Tran Thi, Ngoc Sen Hoang Thi Jan 2026

Attitudes Toward Dementia Among Nursing Students: A Cross-Sectional Study, Ngoc Ha Vo Thi, Thuy Nga Tran Thi, Ngoc Sen Hoang Thi

Health Professions Education

Purpose: Dementia is the loss of cognitive function, including thinking, memory, and communication, due to brain disorders. The global prevalence of dementia is increasing, affecting younger populations. Caring for individuals with dementia requires preparedness to manage behavioral and psychological symptoms. As future healthcare providers, nursing students are expected to have the necessary knowledge and attitudes to support dementia patients. To describe nursing students' attitudes toward dementia and explore related factors.

Methods: A cross-sectional study was conducted on 520 nursing students at Da Nang University of Medical Technology and Pharmacy. A structured questionnaire assessed demographic characteristics, academic information, knowledge, and attitudes …


Exploring Saudi Arabian Efl Teachers’ Experiences With The Flipped Classroom, Amal Bin Dlil Jan 2026

Exploring Saudi Arabian Efl Teachers’ Experiences With The Flipped Classroom, Amal Bin Dlil

Dissertations of Practice

This qualitative phenomenological study aimed to explore the lived experiences of Saudi teachers of English as a Foreign Language (EFL) who implemented the flipped classroom model in a middle school context in southern Saudi Arabia. To achieve this aim, the research questions examined teachers’ descriptions of their lived experiences and perceptions of implementing the flipped classroom strategy, as well as the contextual factors that influenced these experiences in middle school classrooms. To guide the investigation, the study was informed by Active Learning Theory and the Technological Pedagogical Content Knowledge (TPACK) framework, which provided a conceptual lens for examining teachers’ experiences …


Unh: The Magazine Of The University Of New Hampshire, Winter 2026, Unh Magazine Jan 2026

Unh: The Magazine Of The University Of New Hampshire, Winter 2026, Unh Magazine

UNH Magazine

No abstract provided.


Indo-Gothic Architecture And The Reproduction Of Medieval Political Logic In Colonial Calcutta, Sreeja Chowdhury Frsa Jan 2026

Indo-Gothic Architecture And The Reproduction Of Medieval Political Logic In Colonial Calcutta, Sreeja Chowdhury Frsa

Peregrinations: Journal of Medieval Art and Architecture

No abstract provided.


Redeemed Through The Beauty Of Sacred Spaces: How “Church Crawling” Proved To Be A Gift That Never Stops Giving., Cathy Stillman-Lowe Jan 2026

Redeemed Through The Beauty Of Sacred Spaces: How “Church Crawling” Proved To Be A Gift That Never Stops Giving., Cathy Stillman-Lowe

Peregrinations: Journal of Medieval Art and Architecture

No abstract provided.


Annual Report Town Of Milan, Milan, New Hampshire For The Year Ended December 31, 2025, Milan Town Representatives Jan 2026

Annual Report Town Of Milan, Milan, New Hampshire For The Year Ended December 31, 2025, Milan Town Representatives

Milan, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.


Untangling The New Deal Slogan’S Origin Stories, James Kimble Ph.D. Jan 2026

Untangling The New Deal Slogan’S Origin Stories, James Kimble Ph.D.

CHDCM Publications

Existing scholarship on the emergence of Franklin D. Roosevelt’s new deal slogan is inconsistent and incomplete. This article constructs a revised history of the phrase by scrutinizing the contradictory stories of its origin. The investigation initially establishes the historical context by examining the phrase’s trajectory prior to Roosevelt. It then considers the various accounts of those who have been credited with coining the slogan on his behalf. Finally, the article recovers the indispensable contribution of Charles R. Macauley, who has become the forgotten man in debates over new deal’s murky beginnings.


Forage News [2026-02], University Of Kentucky Jan 2026

Forage News [2026-02], University Of Kentucky

Forage News

No abstract provided.


Rethinking Climate Change Education: Wyoming And New Jersey As Effective Models Of Climate Change In Education Standards, Jamie W. Miller Jan 2026

Rethinking Climate Change Education: Wyoming And New Jersey As Effective Models Of Climate Change In Education Standards, Jamie W. Miller

Pitzer Senior Theses

Education is an essential and oft-overlooked part of the conversation about climate change. As I’ll demonstrate in this thesis, education shapes how the public understands climate change and creates environmental knowledge, attitudes, behaviors, and intentions. Exploring and understanding climate change education allows us to understand how people form perspectives about climate issues. This topic is extremely important, but one we often gloss over when thinking about climate solutions. I analyzed three case studies of educational standards in the United States to understand how political context, writing focuses, and benchmarks impact the efficacy of climate change standards. My research found that …


Long Acting Beta2-Adrenergic Receptor Agonists Reverse Diabetic Nephropathy And Liver Steatosis In Murine Models Of Diabetes And Are Associated With Protection In Retrospective Human Studies, Brennan Winkler Jan 2026

Long Acting Beta2-Adrenergic Receptor Agonists Reverse Diabetic Nephropathy And Liver Steatosis In Murine Models Of Diabetes And Are Associated With Protection In Retrospective Human Studies, Brennan Winkler

MUSC Theses and Dissertations

Diabetes Mellitus (DM) affects 13.9% of men and 14.3% of women worldwide, a total of approximately 828 million people. Patients with diabetes are at risk of several complications including diabetic nephropathy (DN) and metabolic-associated steatohepatitis (MASH). These diseases eventually lead to end stage kidney disease (ESKD) and liver failure requiring dialysis and organ transplantation. In addition, diabetes exacerbates disease severity of autosomal dominant polycystic kidney disease (ADPKD), the most common potentially lethal genetic disease to affect humans with a prevalence of 1 in 500-1000. Therefore, a therapeutic approach that can attenuate organ damage and restore function in patients with DM, …


A Scenario Analysis Of The Impact Of H.R.1 2025 Medicaid Coverage Loss And Payment Reductions On U.S. Hospital Operating Margins, Tangee Pruitt Jan 2026

A Scenario Analysis Of The Impact Of H.R.1 2025 Medicaid Coverage Loss And Payment Reductions On U.S. Hospital Operating Margins, Tangee Pruitt

MUSC Theses and Dissertations

The “Big Beautiful Bill” is expected to affect the financial health of U.S. hospitals. We performed a scenario analysis using five case studies combined with national data on payer mix information to illustrate potential impact in 2027. The scenarios explored the following question: What is the expected healthcare access and economic impact of H.R.1 under three sets of assumptions: 1) loss of Medicaid coverage for 10% or more of an institution’s current patients who will then become uninsured; 2) decrease in Medicaid payments by 10% or more; 3) loss of Medicaid coverage and decrease in Medicaid payments simultaneously. We defined …


Compassionate Care In The Library Workplace, Shannon D. Jones Jan 2026

Compassionate Care In The Library Workplace, Shannon D. Jones

MUSC Faculty Bookshelf

This chapter explores the role of compassionate care as a critical leadership practice in the library workplace, with a particular focus on academic health sciences libraries. Drawing on the author’s lived experience as a Black woman library leader and on over two decades in the profession, the chapter situates compassionate care at the intersection of compassionate and inclusive leadership and organizational well-being. In the context of ongoing collective trauma, including the COVID-19 pandemic, racial violence, political polarization, and sustained attacks on libraries, the chapter argues that compassion must move beyond empathy to intentional, actionable leadership. It examines how social identities, …