Digital Commons Network^™

Role Of Novel Renal Biomarkers In Prognosticating Patients With Chronic Kidney Disease: A Prospective Cohort Study, Raghavan Padmanabhan, Kaviya Manoharan, Melina Sahay, Pooja Bhujangarao, Luxitaa Goenka, Solai Priya, Kumaraswamy Subramaniyan, Damal Kandadai Sriram, Melvin George

Turkish Journal of Medical Sciences

Background/aim: Several biomarkers have been assessed for the diagnosis of chronic kidney disease (CKD). However, limited data are available regarding their ability to predict mortality in CKD. The aim of this study was to assess the ability of lipocalin-2, receptor for advanced glycation end products (RAGE), tissue inhibitor of metalloproteinase 1 (TIMP-1), osteopontin, and trefoil factor 3 (TFF-3) in predicting the prognosis of patients with CKD.

Materials and methods: We included patients with CKD as defined by an estimated glomerular filtration rate of <60 mL/min/1.73 m2 of either sex who were above the age of 18 years. Patients with a history of acute-on-chronic kidney disease were excluded. The novel markers of interest were estimated from patients’ plasma samples using the multiplex enzyme-linked immunosorbent assay. These patients were followed for 1 year to assess mortality.

Results: The median (with interquartile range) plasma concentrations of lipocalin-2, RAGE, TIMP-1, osteopontin, and TFF-3 were 56.9 …

Post-Exposure Prophylaxis For Hiv Among Healthcare Workers In Türkiye: A Descriptive, Multicenter Retrospective Study, Veysel Akca, İlkay Akbulut, Gül Ruhsar Yilmaz, Alper Tahmaz, Nefi̇se Öztoprak Çuvalci, İlknur Esen Yildiz, Mehmet Çabalak, Şeyma Topal, Özgür Günal, Bi̇rcan Kayaaslan, Fatma Eser, Tuba Damar Çakirca, Deni̇z Ölmez, Ali̇ye Baştuğ, Fi̇rdevs Aksoy, Hani̇fe Nur Karakoç Parlayan, Beyza Süllü, Damla Verendağ, Hatun Öztürk Çeri̇k, Mehmet Ali̇ Aşan, Ayhan Akbulut, Gülden Eser Karlidağ, Behi̇ce Kurtaran, Hüsnü Pullukçu, Turhan Togan

Turkish Journal of Medical Sciences

Background/aim: Post-exposure prophylaxis (PEP) for human immunodeficiency virus (HIV) plays a vital role in preventing transmission among healthcare workers following occupational exposure. Despite its clinical importance, epidemiological data regarding PEP implementation in Türkiye remain scarce. This study aimed to assess PEP practices, prophylactic treatment regimens, and follow-up outcomes among healthcare workers at risk of occupational HIV exposure.

Materials and methods: This retrospective, multicenter study was conducted between January 2020 and December 2024 across 16 healthcare facilities participating in the National HIV/AIDS Working Group. Healthcare workers aged 18 years and older who presented for evaluation following occupational exposure to HIV were …

Programs Agenda 4-14-26, Angela Brock

Programs Committee (PC)

No abstract provided.

Approved Programs 4-14-26, Angela Brock

Programs Committee (PC)

No abstract provided.

Engineering Ferrate(Vi) For Water And Wastewater Treatment: Translating Science Into Technology, Zepei Tang, Zhenli He, Yang Deng

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

Over the past five decades, ferrate(VI) (FeO42–) for water and wastewater treatment has remained largely at the laboratory scale, with limited pilot- and full-scale implementation. This gap between sustained research and scarce real-world deployment places the technology in the Valley of Death─a high-risk stage of development─and highlights the need for an engineering-centric approach to enable practical application. This article presents an engineering framework to guide the development and translation of ferrate(VI) technology for water and wastewater treatment. From a system perspective, ferrate(VI) technology comprises three core subsystems: generation, treatment, and solid–liquid separation. Technology maturity depends on both the advancement of …

Artificial Intelligence-Assisted Neuropharmacology: Reshaping Drug Discovery And Translational Strategies For Neurological Diseases ​, Pri̇yanka Rathee, Suni̇thi̇ Lohan, Sari̇ta Khatkar, Neelam Mali̇k, Esra Akkol, Renu Sehrawat, Pooja Rathee, Anurag Khatkar

Turkish Journal of Medical Sciences

The rapid expansion of data-driven technologies, particularly machine learning (ML) and artificial intelligence (AI), has substantially influenced biomedical research and drug discovery. In neuropharmacology, the availability of large-scale genomic, proteomic, chemical, and clinical datasets has stimulated the adoption of AI-based approaches to address persistent challenges in neurological drug development, including high attrition rates and the scarcity of disease-modifying therapies. Unlike prior reviews that broadly discuss AI applications in drug discovery or neurology, this narrative review focuses specifically on neuropharmacology, with an emphasis on translational relevance, disease-oriented examples, and real-world constraints. We critically examine the application of AI and ML across …

Impact Of Two Sedation Protocols On Cardiac Electrophysiology During Spinal Anesthesia ​, Selvi̇naz Durantaş, Burak Nalbant, Fatma Kavak Akelma, Gökhan Erdem, Abdulkadi̇r But

Turkish Journal of Medical Sciences

Background/aim: Perioperative factors such as anesthetic drugs, central blocks, surgical stress, pain, and anxiety can affect cardiac electrophysiology and increase the risk of arrhythmias. Arrhythmia susceptibility can be assessed using ventricular markers such as the QT interval (QT), heart rate-corrected QT interval (QTc), QT dispersion (QTd), time between peak and end of T wave (Tp–e), cardiac electrophysiologic balance index (iCEB), and heart rate-corrected index of cardiac electrophysiologic balance (iCEBc), obtained from noninvasive electrocardiography (ECG) data. This study compared the effects of propofol and dexmedetomidine sedation on these parameters in patients undergoing total knee arthroplasty performed under spinal anesthesia.

Materials and …

Analysis Of Calr-Mutated Essential Thrombocythemia As A Distinct Disease Entity Compared With Jak2 V617f-Mutated And Triple-Negative Patients ​, Gökhan Sami̇ Aydin, Eli̇f Aksoy, İpek Yönal Hi̇ndi̇lerden, Aynur Dağlar Aday, Emi̇ne Gültürk, Meli̇ha Nalçaci, Fehmi̇ Hi̇ndi̇lerden

Turkish Journal of Medical Sciences

Background/aim: Calreticulin (CALR) mutations in essential thrombocythemia (ET) are associated with younger age, higher platelet counts, and lower thrombosis rates. The present study analyzes the demographic, laboratory, and clinical features of the CALR mutation and its prognostic impact.

Materials and methods: The clinical impact of CALR mutations was assessed in 391 ET patients.

Results: CALR-mutation patients were more commonly male than JAK2 V617F-positive and triple-negative patients. Age at diagnosis was similar across all groups, although patients with type 2 CALR mutations were younger than those with nontype 1/nontype 2 mutations. Compared with JAK2 V617F-positive patients, CALR-mutation patients had lower leukocyte …

Comprehensive Profiling Of Gut Microbiota In Postmenopausal Osteoporosis ​, Gülsemi̇n Ertürk Çeli̇k, Sedat Yildiz, Münevver Aksoy Bektaş, Yaprak Engi̇n-Üstün

Turkish Journal of Medical Sciences

Background/aim: Osteoporosis is a multifactorial skeletal disease that predominantly affects postmenopausal women and is characterized by reduced bone mass and an increased risk of fractures. Growing evidence suggests that the gut microbiota plays a pivotal role in bone metabolism through immunological, endocrine, and metabolic pathways, forming the basis of the so-called gut– bone axis. This study aimed to characterize gut microbiota composition in postmenopausal women with osteoporosis compared with healthy controls.

Materials and methods: Forty postmenopausal women aged 55–65 years were classified into osteoporosis (n = 20) and healthy control (n = 20) groups based on dual-energy X-ray absorptiometry T-scores. …

Coverage, Traits, And Geographic Distribution Of Online Surgeon Reviews: Large-Scale Cross-Sectional Analysis, Michael Geng, Carlos Riveros, Yash B. Shah, Sanjana Ranganathan, Kai Fok, Renil Sinu Titus, Vatsala Mundra, Eusebio Luna Velasquez, Dharam Kaushik, Allan S. Detsky, Angela Jerath, Benjamin N. Breyer, Yusuke Tsugawa, Christopher J. D. Wallis, Raj Satkunasivam

Student Papers, Posters & Projects

BACKGROUND: The use of online physician rating platforms has significantly increased and has been shown to influence physician selection. There are limited data on the use of these platforms for rating surgeons.

OBJECTIVE: In this study, we sought to assess the geographic distribution of and patterns in rating scores of surgeons in the United States. Additionally, we examined rating volumes across different surgical specialties and the association between peer-nominated and patient-initiated ratings on online rating platforms in the United States.

METHODS: We conducted a cross-sectional study by identifying 201,154 surgeons in the United States via the National Plan and Provider …

The Deregulation Of Cancer, Daniel G. Aaron

Texas A&M Law Review

Fifty years ago, the U.S. embarked on a radical new path. Under pressure from the environmental movement, Congress passed an array of statutes aimed at regulating carcinogens out of our world. This regulatory experiment sprawled from air and water to food and consumer products.

Legal scholars have paid scant attention to this wave of cancer regulation despite its size and importance and the public’s apparent interest in avoiding carcinogens. But there is a growing literature finding flaws with individual regimes within the framework, such as the Clean Air Act, the Toxic Substances Control Act, and the Tobacco Control Act. In …

Individualized Cannabis Reparations, Scott Bloomberg

Texas A&M Law Review

This Article makes an argument that should be obvious. The best way for governments to right the wrongs of cannabis prohibition is to give money to people with cannabis offenses. Nonetheless, this straightforward reform has been consistently overlooked, dismissed, or minimized by policymakers and scholars alike, eschewed in favor of other social equity programs that do not right those wrongs nearly as effectively. Governments have indeed invested hundreds of millions of cannabis tax dollars in social equity licensing programs and community reinvestment initiatives. These programs—while often worthwhile—do not benefit the vast majority of people with past cannabis offenses.

Governments should …

The Unexplored Future Of State Copyrights And Patents In Ai-Generated Creations, Timothy J. Mcfarlin

Texas A&M Law Review

This is the first article to broadly explore the possibility of state copyrights and patents in AI-generated creations and what it could portend for the future of intellectual property law.

The U.S. Constitution delegates to Congress, via Article I, the power to pass laws “securing for limited times to authors and inventors the exclusive right to their respective writings and discoveries.” It reserves to the states or to the people, via the Tenth Amendment, certain unspecified powers not delegated to the federal government. These could include the power to recognize exclusive rights in “writings and discoveries” generated by artificially intelligent …

"The Silence Of The Farms": Suppressing Speech And Trampling Transparency To Shield Big Ag, Erin Okuno

Texas A&M Law Review

Do you really know where your last meal came from and whether it was safe to eat? Most people are not aware of the often appalling conditions at agricultural production facilities (aptly known as “factory farms”), including worker injuries and abuse, contaminated food, and environmental pollution, as well as the horrific ways in which the animals are kept, raised, and slaughtered. In the face of these concerning conditions and alarmingly frequent food recalls—including millions of pounds of contaminated meat—it would seem prudent to increase transparency at factory farms, but historically, they have operated behind a shield of secrecy due to …

Regulating Data Monetization, Peter Ormerod

Texas A&M Law Review

Companies today generate hundreds of billions of dollars each year by collecting massive amounts of information about human activity and wringing predictive insights from it. The scale of these influence activities is stunning: your driving habits dictate your car insurance rates, buying the wrong thing will increase your borrowing costs, and the information ecosystem you inhabit is finely tuned for keeping your attention available to the highest bidder.

States have recently enacted new consumer privacy laws that confer on individuals a series of generally applicable rights over their personal information. But this approach has proven ineffective at disciplining firms’ data …

Hybrid Bermudagrass Dormancy Management In A Cool-Season Climate, Clarissa H. Peterson

Theses and Dissertations

Hybrid bermudagrass (Cynodon dactylon [L.] Pers. × C. transvaalensis Burtt Davy) (HBG) is a water efficient warm-season turfgrass increasingly adopted in cool-season and semi-arid regions due to climate change and the demand for reduced irrigation inputs. However, prolonged winter dormancy limits its visual quality (verdure) and seasonal performance. This thesis evaluated multiple management strategies to modify dormancy dynamics and improve off-season turf quality in a cool-season environment. Field experiments assessed the effects of growth covers, fertilizers, colorants, surfactants, organic acids, and overseeding with cool-season species on HBG dormancy over two seasons. Dormancy responses were quantified using normalized difference vegetation index …

Discovering My Passion For Social Justice, Nev Hommel '26

Senior Presentation of Learning

After taking a tour of DePauw in the fall of 2021, I knew it was my school. However, I didn’t know how I could afford to attend. I scoured DePauw’s website for scholarships and found out about Bonner! I’m so grateful I took a leap of faith and applied. I was thrilled to find out I was accepted into the program! Upon arriving at DePauw for Bonner orientation, I immediately felt welcomed by Val and my fellow Bonners. Bonner has brought me an amazing community of friends and peers. Furthermore, the Bonner program introduced me to the world of social …

Rooted In Service, Reaching For The Stars, Lucila Ojeda '26

Senior Presentation of Learning

My biggest takeaway from Bonner is to not be afraid to ask for help. Coming from out of state, the transition from a familiar community to somewhere completely foreign was scary. The kindness shown to me by the people at Bonner is something I will never forget. Do it scared and take the leap of faith in reaching out and building your community. Bonner will help you as much as they can, and I hope my service has reflected the support I have been so fortunate to receive.

From Beauty To Burden: Mapping The Health And Psychosocial Impacts Of Fragrances And Cosmetic Products Use In The Uae, Sharifa Alblooshi, Mariam Al Ali, Dana N. Abdelrahim, Suheir Awadalla

All Works

Background The dynamic beauty care sector in the Middle East is on an upward trend in the UAE; however, concerns persist about the side effects of this industry, attributed to chemical exposure, which is believed to contribute to skin problems and other health issues. In the UAE, there is a lack of data on consumer usage, awareness, and the health effects associated with it.Methods This study presents the results of an online survey administered to 461 female subjects in the United Arab Emirates as part of a cross-sectional study. The survey consisted of 55 questions on product use, knowledge, attitudes, …

Ucc Minutes 4-14-26, Angela Brock

UCC Agendas/Minutes

No abstract provided.

Approved Courses 4-14-26, Angela Brock

Individual Course Committee (ICC)

No abstract provided.

Spartan Daily, April 14, 2026, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2026

Volume 166, Issue 32

Prognostic Significance And Clinicopathological Associations Of Tumor Budding And Poorly Differentiated Clusters In Endometrioid Endometrial Carcinoma ​, Hani̇fe Seda Mavi̇li̇, Ömer Atmiş, Fatma Seher Pehli̇van, Fatma Sezen Çavdaroğlu Deveci̇, Ali̇ Riza Kandi̇loğlu

Turkish Journal of Medical Sciences

Background/aim: Tumor budding (TB) and poorly differentiated clusters (PDCs) are histopathological parameters that have been associated with poor prognosis in various malignancies, particularly colorectal carcinoma. Although numerous studies have demonstrated an association between the microcystic, elongated, and fragmented (MELF) pattern in endometrial carcinomas and lymphovascular invasion as well as lymph node metastasis, the literature regarding TB and PDCs in this context remains limited. This study aimed to investigate the potential associations of the MELF pattern, TB, and PDCs with overall survival, progression-free survival, and clinicopathological parameters in cases of endometrioid endometrial carcinoma (EEC).

Materials and methods: A total of 190 …

Hypertext Transfer Protocol Fingerprinting: Techniques For Attacker-In-The-Middle Proxy Detection, Evasion, And Counter-Evasion, Jensen George Wood

Theses and Dissertations

Attacker-in-the-middle (AitM) phishing toolkits have emerged as a critical threat to enterprise and individual security by enabling adversaries to bypass multi-factor authentication (MFA) and compromise cloud-based accounts at scale. Traditional detection techniques--such as IP blocklists or content-based detection methods--are often ineffective against these increasingly sophisticated attacks. We propose a novel method that detects malicious proxies by identifying artifacts they introduce into HTTP request headers. To evaluate our approach, we systematically analyze traffic passed through several open-source AitM toolkits and proxies, identifying distinct modifications to header structures and content, then formalize these features as YARA rules for automated use. To validate …

Further Development Of A Low-Energy Arc-Ignition System For Nytrox/Abs Hybrid Propulsion Systems, Stephen A. Whitmore, Jared S. Coen, Ryan J. Thibaudeau

Mechanical and Aerospace Engineering Faculty Publications

Utah State University has developed a high-performance “green” hybrid propulsion technology based on the unique electrical breakdown properties of 3D-printed acrylonitrile butadiene styrene. Using 3D-printed ABS as fuel, typical startup sequences require approximately 5–15 joules and, once started, the system can be sequentially fired with no additional energy inputs required. The number of possible ignitions is limited only by the amount of fuel. The most technologically mature version uses gaseous oxygen (GOX) as oxidizer and 3D-printed ABS as fuel. While GOX is mass-efficient, it lacks volumetric efficiency unless highly pressurized. Nytrox, a blend of GOX and nitrous oxide, improves propellant …

From Disaster To Decision: Spatial And Temporal Patterns In Disaster-Affected Voting, Jake L. Shaw

Dissertations

This dissertation examines how natural disasters shape electoral behavior in gubernatorial and presidential elections in the United States, with particular attention to geographic proximity, disaster severity, and partisan accountability. Using county-level gubernatorial and presidential election returns from 2016 to 2022, it analyzes the electoral effects of hurricanes, wildfires, and tornadoes through three frameworks: direct disaster impact, near-distance exposure, and disaster severity. Employing the difference-in-differences and fixed effects models across more than 31,000 county-year observations, the study finds that natural disasters can significantly reduce incumbent party vote share and voter turnout, particularly in gubernational elections. Results further demonstrate that electoral effects …

Mastery By Mistakes: Reframing Failure In Higher Education Skill-Based Teaching And Assessment, Maura Metheny

JWU Dissertations & Theses

Experiencing a mistake, error or failure while learning generates an additional inquiry process that activates prior knowledge and increases retention of subsequent feedback and new material (Kapur, 2008). The use of errors to guide practice has been shown to lead to skill-mastery and expertise (Ericsson et al., 1993). When classrooms are psychologically safe environments where penalty-free exploration and knowledge application are encouraged, students gain a deeper understanding of the content (Tulis, 2013). This qualitative exploratory descriptive study aimed to understand the ways that undergraduate faculty in skill-based disciplines involve errors, mistakes and failures in teaching and …

Trading Precarities: How Bangladeshi Freelancers Leverage The Digital Economy Amid Local Insecurity And Ai Disruption, Naim Bin Hasan

Electronic Theses and Dissertations 2020 - Present

This study examines how Bangladeshi freelancers use digital platform work to cope with precarious local labor markets and how this strategy both mitigates and reproduces insecurity. In this form of work, freelancers compete for short-term, skill-based remote jobs posted by global clients. Drawing on 30 in-depth interviews and virtual ethnography, this study challenges dominant Western understandings of the precariat that assume workers fall from stable employment into insecure work. Instead, the findings show that many freelancers enter platform labor strategically as a way out of already unstable and limited local opportunities. While freelancing carries a promise of foreign income, flexibility, …

Suppressing Saints And Suffering Sinners: An Analysis Of Reductive Tropes Through The 2025 Film Sinners, Kaila Palmer

Electronic Theses and Dissertations 2020 - Present

Ryan Coogler’s 2025 horror film Sinners is set in a predominantly Black Mississippi community during the Jim Crow era and explores the vulnerability and hypervisibility of Black people. Vampires and Klansmen fixate on Black bodies, treating them as consumable and dispensable sources. Prior to its Amazon Prime debut and extended theatrical run, Sinners grossed over $300 million, signaling its cultural impact and contribution to reshaping representations of Black identity in cinema. As part of Coogler’s broader array of Black storytelling, the film disrupts entrenched stereotypes by emphasizing character depth rather than caricature.

This paper analyzes the characters Annie and the …

Safety And Efficacy Of Ciltacabtagene Autoleucel For Relapsed/Refractory Multiple Myeloma: A Cibmtr Study., Doris K Hansen, Danai Dima, Hira Mian, Jakob Devos, Ruta Brazauskas, Temitope Oloyede, Aimaz Afrough, Nausheen Ahmed, Larry Anderson, Rahul Banerjee, Jesus G Berdeja, Aram Bidikian, Binod Dhakal, Ajoy Dias, Yvonne Efebera, Muhammad Salman Faisal, Lohith Gowda, Hamza Hashmi, Abu-Sayeef Mirza, Meera Mohan, Ravi Narra, Ashley E Rosko, Mark Schroeder, Taiga Nishihori, Heather Landau, Saad Usmani, Marcelo C Pasquini, Othman S Akhtar, Surbhi Sidana, Krina K Patel

Oncology Articles

Ciltacabtagene autoleucel (cilta-cel), an anti-B-cell maturation antigen (BCMA) chimeric antigen receptor T-cell (CAR-T) therapy, was approved in 2022 for heavily pretreated relapsed/refractory multiple myeloma (RRMM). This study evaluates the safety and efficacy of cilta-cel in RRMM patients reported to the Center for International Blood and Marrow Transplant Research registry between March 2022 and December 2023 who met commercial release specifications. Among 595 patients, median age was 64 years, 57% were male, and 70% had ≥1 comorbidity. Extramedullary disease and marrow plasma cell burden ≥ 50% were present in 13% and 14% of patients, respectively. The median number of prior lines …