Digital Commons Network^™

Positive Effects Of Health Behaviors Acquired During The Covid-19 Pandemic Process On The Prevention Of Other Infectious Diseases, Asi̇ye Çi̇ğdem Şi̇mşek, Turan Buzgan, Fatma Nur Baran Aksakal, Şuayip Bi̇ri̇nci̇, Hülya Şi̇ri̇n

Turkish Journal of Medical Sciences

Background/aim: It was aimed to evaluate the positive effects of health behaviors (general hygiene, wearing face masks, physical distancing, and travel restrictions) acquired during the coronavirus disease 2019 (COVID-19) pandemic on the prevention of other infectious diseases in Ankara Province, Türkiye. Materials and methods: This study was designed retrospectively. Among the notifiable group A infectious diseases, acute intestinal infections (AIIs) with International Classification of Diseases, Tenth Revision diagnosis codes A09 (diarrhea and gastroenteritis presumed to be of infectious origin), R11 (nausea and vomiting), and K52 (other noninfectious gastroenteritis and colitis) , as well as influenza, tuberculosis, measles, varicella, malaria, and …

12.04.2023 Orsp Connect, Liz Williamson

ORED Newsletter

Week of December 4, 2023

2023-December-12-Etsu Rotc Cadets Will Earn Commissions.Pdf, University Marketing And Communication, East Tennessee State University

ETSU News

The community is invited to celebrate the commissioning of cadets in the Army ROTC Program at East Tennessee State University, an elite program that is ranked No. 1 in the Volunteer State.

The 1 p.m. ceremony is in the Brown Hall Auditorium, located on the university’s main campus along Stout and Sherrod Drive near University School, on Friday, Dec. 15.

ETSU alumni Gary McAllister, a retired colonel, will be the guest speaker. The university inducted McAllister, a 1983 ETSU graduate with a distinguished military career, into the ROTC Hall of Fame earlier this year.

On Friday, the following ETSU cadets …

Migrant Labour Protection In Asean, In What Way Does Ilo Matter?, Dwi Ardhanariswari Sundrijo, Dhanny Safitri

Global: Jurnal Politik Internasional

Despite the importance of labour migration in Southeast Asia, the mechanism of migrant workers protection in the region is still lacking. Because of that, cases show that often the undocumented and/or the low-skilled workers receive inappropriate treatment in the host countries. In certain cases, they were treated as second-class citizens – this is despite the work that they do. To address these issues, ASEAN has conducted a series of dialog forums and issued various agreements. In doing so, ASEAN have been involving different key stakeholders working on the issue, including international organizations, regional and national civil society organizations, and employers’ …

2023-December-12-Etsu Student Will Fulfill Promise At Commencement.Pdf, University Marketing And Communication, East Tennessee State University

ETSU News

All of the East Tennessee State University students who cross the commencement stage later this month will no doubt feel a range of emotions, from a deep sense of pride and excitement to reflective nostalgia and gratitude.

It will be especially meaningful for senior James “Jack” Smithey, an interior architecture major who already has a job lined up in Nashville.

On December 16, 2009 – 14 years to the day from ETSU’s commencement ceremony – he made a promise to his dad.

The pledge: He would attend and ultimately graduate from college.

“My grandfather had gotten into some trouble, and …

Study Protocol For A Randomized Controlled Trial Of Realconsent2.0: A Web‑Based Intervention To Promote Prosocial Alcohol‑Involved Bystander Behavior In Young Men, Laura F. Salazar, Dominic J. Parrott, David Dilillo, Sarah J. Gervais, Anne Marie Schipani‑Mclaughlin, Ruschelle Leone, Kevin Swartout, Lauren Simpson, Renita Moore, Tiffany Wilson, Nyla Flowers, Haley Church, Amanda Baildon

Department of Psychology: Faculty Publications

Background Sexual violence (SV) is a significant, global public health problem, particularly among young adults. Promising interventions exist, including prosocial bystander intervention programs that train bystanders to intervene in situations at-risk for SV. However, these programs suffer from critical weaknesses: (1) they do not address the proximal effect of alcohol use on bystander decision-making and (2) they rely on self-report measures to evaluate outcomes. To overcome these limitations, we integrate new content specific to alcohol use within the context of prosocial bystander intervention into an existing, evidence-based program, RealConsent1.0. The resulting program, RealConsent2.0, aims to facilitate bystander behavior …

The Diamond, December 12, 2023, Dordt University

Dordt Diamond

• Front Page: Dordt Begins Construction on Townhome Style Housing; Dordt Alumni Elected as Mayor of Sioux Center; Morality and Policy Collide at Feenstra's Faith and Family Event
• News: Voters Prepare for Iowa's January Caucus; Finals Shift Away from Traditional Exams; MOSAIC Club, Students Without Borders Hosts Christmas Around the World; Iowa Corn Includes College Agriculture Students
• Feature: Student-Led Short Films Showcase Talents; Zamboni Breaks the Ice at Dordt Hockey; Escaping War and Finding a Home in Sioux County; Dordt Dads Lend a Hand by Washing Dishes; Developing Your Career at Dordt
• Arts & Entertainment: Student-Directed One …

Void Formation And Mortality During Liquid Composite Molding, Jared Michael Turner

Theses and Dissertations

Within the high-performance composite manufacturing industry, there exists a need to improve the reliability of LCM (Liquid Composite Molding) manufacturing processes in producing composite parts that better approach the quality and consistency of pre-impregnated composite tapes that are cured in autoclaves with cost being a driving factor of this need. One obstacle to that end is the phenomenon of void formation during the LCM infusion processes. The formation of these voids through different mechanisms leads to composite parts with lower mechanical properties and consistency than their pre-impregnated autoclave cure counterparts. The objective of this research is to investigate the different …

Characterizing Quirky Signals, Joshua D. Forsyth

Theses and Dissertations

Large collider facilities such as the Large Hadron Collider (LHC) employ a variety of search methods in hopes of finding new particles. It may be that new physics beyond the SM is waiting to be discovered at energies accessible to the LHC. Quirks are particles charged under a new confining gauge group with masses much larger than their confinement scale. This project details the dynamics of quirks, as well as the production and decay of electrically charged bound states of scalar quirks. The cross section for these states is compared to existing Wγ resonance searches at the LHC. Such a …

In Vitro Observation Of Optical Changes In Whole Blood Due To Injection Of Glucose Solution, James Gordon Harkness

Theses and Dissertations

Significance: While the optical properties of blood have been extensively studied, the influence of glucose concentration on blood optics remains unquantified. This is information which could be used to develop a noninvasive blood glucose monitor. Aim: This in vitro study investigated the optics of blood. Time-dependent effects and various methods of introducing glucose into blood samples were examined. The study aimed to quantify how alterations in glucose levels impacted blood optics across 14 distinct NIR wavelengths. Approach: Blood in a cuvette was exposed to light, and the reflected and transmitted light was captured in integrating spheres. 14 distinct wavelengths from …

The State Of Active Blended Learning In Construction Education: Reviewing Research And Current Perspectives, Shandon Miles Gubler

Theses and Dissertations

STEM educators have shown a particular interest in active blended learning. Construction management education, a discipline within STEM education, has naturally considered blended instruction to engage students in the learning process. Documented efforts of construction management educators implementing blended instruction have mostly been recorded in conference proceedings. These recorded efforts often take the form of anecdotal case studies—a current review of how construction management faculty are implementing blended instruction and active learning in their blended courses was not found. In this study, we reviewed the literature for active blended instruction in construction management education. We surveyed construction management faculty about …

Linking Individual Behavior With Physiology To Understand Complex Life Histories, Doreen Cabrera

Theses and Dissertations

Life history strategies encompass a suite of co-evolved traits crucial for ensuring an individual's fitness, often evolving from trade-offs between traits competing for the same resources. Adult male crayfish in the Cambaridae family undergo seasonal morphological changes linked to reproductive status, a process called cyclic dimorphism. In this dissertation, we attempt to understand how cyclic dimorphism evolved in non-native northern crayfish (Faxonius virilis). First, in Chapter 1, we review empirical studies that have assessed animal personality across developmental periods. The results show that personality traits tend to be stable within life stages but not across developmental events. In Chapter 2, …

Commercial Adsorbents For Co2 Removal For Biogas Upgradation: An Experimental Study, Aakriti Bagla

McKelvey School of Engineering Graduate Student Theses & Dissertations

No abstract provided.

Quantifying Non-Muscle Myosin 2 Filament Dynamics, Melissa Ann Quintanilla

Dissertations

Non-muscle myosin 2 is a motor protein that, when assembled into filaments, works on the actin cytoskeleton to produce contractile forces within cells. This type of myosin dynamically assembles within cells to exert forces necessary for a wide variety of functions including cell division, migration, and multicellular movement. The ability to dynamically assemble contractile networks, and the ability to control the assembly and placement of these myosin filaments in both space and time, is therefore required throughout cell physiology. We used a suite of dynamic, quantitative imaging approaches to identify deterministic factors that drive myosin filament appearance and amplification as …

The Experience Of Teaching Disengaged Students In Stem: Examined Through The Lens Of The Abc Engagement Framework, William Randall Hjorth

Theses and Dissertations

Young people today are increasingly disengaged from their education. Studies indicate that of all school subjects, American students struggle to engage in STEM subjects more than others. For decades, we have known that student engagement/disengagement impacts teachers. Researchers have also claimed that engagement/disengagement can be described as a construct made up of affective, behavioral, and cognitive dimensions (ABC). However, we do not understand how teachers experience student disengagement in these three areas. At a crucial time in education, investigation into the experiences of teachers with disengaged students is needed to uncover insights which may help us understand how teachers interpret …

Motherland Drip: Examining Performativity In Southern Black Motherhood, Daisha Huiel

Master's Projects

This capstone project explores the possibilities of the societal standards of southern Black motherhood creating oppositional experiences for Black women and their claims to freedom and bodily autonomy. I am writing about the lived experiences of southern Black women, including myself, within their communities to explore anti-respectability themes in the lives and performances of southern women and female hip hop performers through the lens of intersectionality. This creative nonfiction1 and scholarship reflect my academic exploration into the ways foundational Black feminist theory and relevant texts connect to my individual lived experiences of motherhood and identity within the post-hip-hop generations. I …

Unh Celebrates Students And Alumni At Annual Social Venture Innovation Challenge, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Patterns And Predictors Of Racial/Ethnic Disparities In Hiv Care Continuum In The Southern Usa: Protocol For A Population-Based Cohort Study, Xueying Yang Ph.D., Jiajia Zhang Ph.D., Bankole Olatosi Ph.D., Zhenlong Li, Sharon Weissman, Xiaoming Li Ph.D.

Faculty Publications

Introduction Health disparities exist at every step of the HIV care continuum (HCC) among racial/ethnic minority population. Such racial/ethnic disparities may have significantly delayed the progress in HCC in the Southern US states that are strongly represented among geographic focus areas in the 2019 federal initiative titled 'Ending the HIV Epidemic: A Plan for America'. However, limited efforts have been made to quantify the long-term spatiotemporal variations of HCC disparities and their contributing factors over time, particularly in the context of COVID-19 pandemic. This project aims to identify the spatiotemporal patterns of racial disparities of each HCC outcome and then …

A Path To Full Citizenship: The Impact Of The Civil Rights Movement On The Creation Of Title I Schools Through The Elementary And Secondary Education Act Of 1965, Edwin Ryan

Washington Semester Program

Studies of the Civil Rights Movement commonly include events like Brown v. Board of Education, the Civil Rights Act of 1964, the Voting Rights Act of 1965, sit-ins, bus boycotts, and the Freedom Riders. The creation of Title I schools through the Elementary and Secondary Education Act (ESEA) in 1965 to serve "disadvantaged" students also was a major move in a broader attempt to undo systematic Black poverty. As part of his War on Poverty in the formation of a "Great Society," President Lyndon Johnson and his administration proposed drastic increases for federal involvement in the funding of public school …

Volume 122, Number 3 - Tuesday, December 12th, 2023, Saint Mary's College Of California

The Collegian

No abstract provided.

In-Depth Geochemical Analysis Of Turbidite-Associated Shales Of The Pindos Basin, Greece, Jonathon Michael Sevy

Theses and Dissertations

Detailed geochemical analysis of the turbidite-associated shales of the Cretaceous Katafito Formation, Greece, reveals important details regarding the paleoenvironment, paleoproductivity, and regional tectonics of the Pindos Basin. The Katafito Formation was deposited along an active margin at the early onset of closure of the Tethys Sea in the Pindos sub-basin. While careful studies of the coarse clastic component of turbidites are common, this study consisted of a detailed geochemical characterization of the fine-grained portions, which helped reveal paleoenvironmental information about the basin. This study combined organic and inorganic geochemistry utilizing elemental, mineralogical, and organic chemical signatures from fine-grained turbidite-associated sediments …

Relationship Between Positive Body Image And Selective Visual Self-Presentation On Social Networking Sites: Moderating Role Of Gender, Asharf Sadat Ahadzadeh, Fon Sim Ong, Saeed Pahlevan Sharif

Makara Human Behavior Studies in Asia

This study examines the association between positive body image and selective visual self-presentation behaviors on social networking sites, while also considering the moderating influence of gender. We conducted a cross-sectional survey involving 282 undergraduate students in Malaysia (Mage = 20.85, SD = 1.81). The results reveal a negative correlation between positive body image and behaviors such as posing in pictures and editing photos. However, no significant relationship was found between positive body image and photo selection. Gender differences were evident, with females exhibiting higher engagement in posing in pictures, editing, and photo selection compared to males. The findings also …

Analisis Sistem Proteksi Kebakaran Dan Keselamatan Kebakaran Di Stasiun Transit Manggarai Kereta Rel Listrik (Krl) Commuter Line Jabodetabek Tahun 2023, Naila Adinda Achmad, Hendra Hendra

National Journal of Occupational Health and Safety

Stasiun Manggarai is the most active station. In January 2023, Stasiun Manggarai has 150,000 transit users and 14,000 station users per day (Fransisca, 2023). This large number of users can certainly increase the density – and according to research – density can increase the existing potential hazards and risks, including fire hazards. Therefore, this research was conducted to find out the implementation of fire protection and fire safety system at Stasiun Transit Manggarai Kereta Rel Listrik (KRL) Commuter Line Jabodetabek using a descriptive observational method with comparative approach. The author compares the results of implementing fire protection and fire safety …

Oncogenic Kras Drives Lipofibrogenesis To Promote Angiogenesis And Colon Cancer Progression, Wen-Hao Hsu, Kyle A Labella, Yiyun Lin, Ping Xu, Rumi Lee, Cheng-En Hsieh, Lei Yang, Ashley Zhou, Jonathan M Blecher, Chang-Jiun Wu, Kangyu Lin, Xiaoying Shang, Shan Jiang, Denise J Spring, Yan Xia, Peiwen Chen, John Paul Shen, Scott Kopetz, Ronald A Depinho

Faculty, Staff and Student Publications

Oncogenic KRAS (KRAS*) contributes to many cancer hallmarks. In colorectal cancer, KRAS* suppresses antitumor immunity to promote tumor invasion and metastasis. Here, we uncovered that KRAS* transforms the phenotype of carcinoma-associated fibroblasts (CAF) into lipid-laden CAFs, promoting angiogenesis and tumor progression. Mechanistically, KRAS* activates the transcription factor CP2 (TFCP2) that upregulates the expression of the proadipogenic factors BMP4 and WNT5B, triggering the transformation of CAFs into lipid-rich CAFs. These lipid-rich CAFs, in turn, produce VEGFA to spur angiogenesis. In KRAS*-driven colorectal cancer mouse models, genetic or pharmacologic neutralization of TFCP2 reduced lipid-rich CAFs, lessened tumor angiogenesis, and improved overall survival. …

Kids For A Happy Marriage? A Preliminary Study On Marriage Satisfaction And Presence Or Absence Of Children Among Married Individuals In Indonesia, Alftisya Victory Hutabarat, Karel Karsten Himawan

Makara Human Behavior Studies in Asia

Having children after marriage tends to be seen as a normative practice in Indonesia. As a result, individuals who do not have children could be at risk of experiencing a set of social stigmas. The study aims to explore whether having children is associated with one’s marital satisfaction. In particular, the present study aims to explore the differences in marital satisfaction among married individuals who have biological children, who are childfree (voluntarily childless), and who are childless (involuntarily childless). A cross-sectional survey was conducted to 210 married individuals (M age = 34.3; SD = 7.9). The result shows that …

New Age Insights: Filipino Millennials In Government, Mark Kevin C. Chua, Sherrie Ann C. Labid, Lovely Rose A. Bolante

Makara Human Behavior Studies in Asia

Millennials comprise a significant portion of the demography of the current Philippine workforce. Cognizant of the unique socio-cultural environment that shaped the Generation Y cohort, this descriptive phenomenological qualitative study aimed to explore millennial employees' work expectations and experiences within a government agency in the Philippines. Four themes emerged from the in-depth analysis of the five employees' interview responses: (1) job security and financial stability, (2) socio-emotional support, (3) fulfillment, and (4) professional development opportunities. The qualitative findings of this study emphasize the importance of supporting millennial employees' career growth and fostering a healthy work environment. It indicates that millennial …

Review Of "Is Social Justice Just?", Jonathan Lawler

The Christian Librarian

No abstract provided.

Expression Of Pfkfb Isoenzymes During In Vitro Differentiation Of Mouse Embryonic Stem Cells Into Insulin-Producing Cells, Sai̇me Güzel, Abdullah Yalçin, Yunus Gürpinar, Sabi̇re Güler

Turkish Journal of Medical Sciences

Background/aim: Type 1 diabetes mellitus (T1DM) is caused by the autoimmune-mediated destruction of insulin-producing cells (IPCs) and still has no effective cure. Better understanding of the molecular mechanisms involved in the differentiation of embryonic stem cells (ESCs) into IPCs may help us improve the therapeutic strategies for treating T1DM. 6-phosphofructo-2-kinase/fructose-2,6- bisphosphatases (Pfkfb1-4) are key regulators of glucose metabolism. Although Pfkfb3 has been shown to be required for the growth of early differentiated mouse ESCs (mESCs), more studies are needed to further assess the roles of Pfkfb isoenzymes in embryonic development and differentiation, particularly into specific cell types. In this study, …

Xtx101, A Tumor-Activated, Fc-Enhanced Anti-Ctla-4 Monoclonal Antibody, Demonstrates Tumor-Growth Inhibition And Tumor-Selective Pharmacodynamics In Mouse Models Of Cancer, Kurt A. Jenkins, Miso Park, Magali Pederzoli-Ribeil, Ugur Eskiocak, Parker Johnson, Wilson Guzman, Megan Mclaughlin, Deborah Moore-Lai, Caitlin O'Toole, Zhen Liu, Benjamin Nicholson, Veronica Flesch, Huawei Qiu, Tim Clackson, Ronan C. O'Hagan, Ulrich Rodeck, Margaret Karow, Jennifer O'Neil, John C. Williams

Department of Dermatology and Cutaneous Biology Faculty Papers

INTRODUCTION: The clinical benefit of the anti-CTLA-4 monoclonal antibody (mAb) ipilimumab has been well established but limited by immune-related adverse events, especially when ipilimumab is used in combination with anti-PD-(L)1 mAb therapy. To overcome these limitations, we have developed XTX101, a tumor-activated, Fc-enhanced anti-CTLA-4 mAb.

METHODS: XTX101 consists of an anti-human CTLA-4 mAb covalently linked to masking peptides that block the complementarity-determining regions, thereby minimizing the mAb binding to CTLA-4. The masking peptides are designed to be released by proteases that are typically dysregulated within the tumor microenvironment (TME), resulting in activation of XTX101 intratumorally. Mutations within the Fc region …

Formate Supplementation Enhances Antitumor Cd8+ T-Cell Fitness And Efficacy Of Pd-1 Blockade, Jared H Rowe, Ilaria Elia, Osmaan Shahid, Emily F Gaudiano, Natalia E Sifnugel, Sheila Johnson, Amy G Reynolds, Megan E Fung, Shakchhi Joshi, Martin W Lafleur, Joon Seok Park, Kristen E Pauken, Joshua D Rabinowitz, Gordon J Freeman, Marcia C Haigis, Arlene H Sharpe

Faculty, Staff and Student Publications

UNLABELLED: The tumor microenvironment (TME) restricts antitumor CD8+ T-cell function and immunotherapy responses. Cancer cells compromise the metabolic fitness of CD8+ T cells within the TME, but the mechanisms are largely unknown. Here we demonstrate that one-carbon (1C) metabolism is enhanced in T cells in an antigen-specific manner. Therapeutic supplementation of 1C metabolism using formate enhances CD8+ T-cell fitness and antitumor efficacy of PD-1 blockade in B16-OVA tumors. Formate supplementation drives transcriptional alterations in CD8+ T-cell metabolism and increases gene signatures for cellular proliferation and activation. Combined formate and anti-PD-1 therapy increases tumor-infiltrating CD8+ T cells, which are essential for …