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Distance From A Cultural Model Of Substance Use Risk, Internalization, And Self-Stigma In Urban Brazil, Nicole L. Henderson, William W. Dressler, Natalia Priolli Jora Pegoraro, Ana Falcao, Sandra Cristin Pillon Dec 2023

Distance From A Cultural Model Of Substance Use Risk, Internalization, And Self-Stigma In Urban Brazil, Nicole L. Henderson, William W. Dressler, Natalia Priolli Jora Pegoraro, Ana Falcao, Sandra Cristin Pillon

APC Fund

Introduction: A cognitive theory of culture as socially distributed cultural models has proven useful in research. Cultural models exist in two forms: the model shared by individuals in a social group, and individual versions of that model modified by personal experience. In previous research we documented a shared cultural model of substance use risk among a general population sample in urban Brazil. Here we examine how this model is distributed among persons under treatment for substance use/misuse and the implications for perceived and self-stigma.

Methods: A convenience sample of 133 persons under treatment rated the influence of risk factors for …


Progress Towards The Development Of Asymmetric Conditions For Intramolecular Heteroatom/Dehydro-Diels-Alder Reactions For Synthesizing Furo[3,4-C] Pyranones And Anticancer Podophyllotoxins, Peter Mpaata Dec 2023

Progress Towards The Development Of Asymmetric Conditions For Intramolecular Heteroatom/Dehydro-Diels-Alder Reactions For Synthesizing Furo[3,4-C] Pyranones And Anticancer Podophyllotoxins, Peter Mpaata

Theses and Dissertations

Furo[3,4-c] pyranone is a unique bicyclic molecular structure found in bioactive sesquiterpene isobolivianine and in artificial cytotoxic stilbene derivatives. The structure of furo[3,4-c] pyranone is analogous to cyclopenta[c] pyran structure found in potent cytotoxic iridoids like catapol. Chiral substrates for intramolecular hetero-Diels-Alder (IHDA) reaction have been synthesized in yields ranging from 39% to 81%. These compounds undergo [4+2] cycloaddition via ambimodal/ bispericyclic process to give a mixture of furo[3,4-c] pyranone in yields ranging 40-70% and aryl tetralin lactone derivatives. Density functional theory (DFT) calculations have been performed to gain insight into the mechanism leading to the formation of these compounds. …


Principals’ Roles In Developing A Positive School Culture Through Communication And Building Relationships, Manakshi Panindranauth Dec 2023

Principals’ Roles In Developing A Positive School Culture Through Communication And Building Relationships, Manakshi Panindranauth

Journal of Educational Leadership in Action

This qualitative phenomenological study aimed to explore high school principals’ perceptions of how a supportive environment, strong family-community ties, and trust assist educational leaders in improving the culture within their schools. Participants of this study included 15 high school principals in the New York City Department of Education’s public schools. Data were captured through virtual interviews, where all participants were asked the same questions and analyzed through themes and codes. The three research questions that guided this study included how principals perceive creating a positive school culture by (a) improving the supportive environment; (b) improving strong family-community ties; and (c) …


High-Throughput Deconvolution Of 3d Organoid Dynamics At Cellular Resolution For Cancer Pharmacology With Cellos., Patience Mukashyaka, Pooja A Kumar, David J Mellert, Shadae Nicholas, Javad Noorbakhsh, Mattia Brugiolo, Elise T Courtois, Olga Anczuków, Edison Liu, Jeffrey Chuang Dec 2023

High-Throughput Deconvolution Of 3d Organoid Dynamics At Cellular Resolution For Cancer Pharmacology With Cellos., Patience Mukashyaka, Pooja A Kumar, David J Mellert, Shadae Nicholas, Javad Noorbakhsh, Mattia Brugiolo, Elise T Courtois, Olga Anczuków, Edison Liu, Jeffrey Chuang

Faculty Research 2023

Three-dimensional (3D) organoid cultures are flexible systems to interrogate cellular growth, morphology, multicellular spatial architecture, and cellular interactions in response to treatment. However, computational methods for analysis of 3D organoids with sufficiently high-throughput and cellular resolution are needed. Here we report Cellos, an accurate, high-throughput pipeline for 3D organoid segmentation using classical algorithms and nuclear segmentation using a trained Stardist-3D convolutional neural network. To evaluate Cellos, we analyze ~100,000 organoids with ~2.35 million cells from multiple treatment experiments. Cellos segments dye-stained or fluorescently-labeled nuclei and accurately distinguishes distinct labeled cell populations within organoids. Cellos can recapitulate traditional luminescence-based drug response …


Physically And Chemically‑Crosslinked L‑Arginine‑Loaded Polyvinyl Alcohol‑ Hyaluronic Acid‑ Cellulose Nanocrystals Hydrogel Membranes For Wound Healing: Influence Of Crosslinking Methods On Biological Performance Of Membranes In‑Vitro, Elbadawy A. Kamoun, Elbadawy A. Kamoun Dec 2023

Physically And Chemically‑Crosslinked L‑Arginine‑Loaded Polyvinyl Alcohol‑ Hyaluronic Acid‑ Cellulose Nanocrystals Hydrogel Membranes For Wound Healing: Influence Of Crosslinking Methods On Biological Performance Of Membranes In‑Vitro, Elbadawy A. Kamoun, Elbadawy A. Kamoun

Nanotechnology Research Centre

Two types of polyvinyl alcohol-blended hyaluronic acid and cellulose nanocrystals (PVA/HA/CNCs) hydrogels membranes were developed as delivery agents for L-arginine using chemical/and/physical crosslinking methods for exploring biological performance of the obtained membranes. Chemically and physically/crosslinked membranes were fabricated by solution-casting and freeze-thawing techniques, respectively. The characterization of the crosslinked PVA/HA/CNCs/Larginine membranes were conducted by SEM, FTIR, TGA, swelling ratio, and in—vitro L-arginine release. Furthermore, applying two types of crosslinked membranes in vitro were investigated in terms of cytotoxicity, hemocompatibility, and cell adhesion affinity of HFB-4 cell line. Chemical and physical-crosslinked membranes were verified through the esterification and hydrogen bonds interactions, …


2023-December-18-Etsu Psychology Working To Meet National Needs.Pdf, University Marketing And Communication, East Tennessee State University Dec 2023

2023-December-18-Etsu Psychology Working To Meet National Needs.Pdf, University Marketing And Communication, East Tennessee State University

ETSU News

The results are consistent, as well as troubling.

For three straight years, psychologists across the United States report seeing patients enduring an increase in mental health symptoms, often resulting in longer treatment time.

The gist: Psychologists aren’t sure they can meet the incredible need, according to the annual survey from the American Psychological Association.

Prizing hands-on learning and relevant research, East Tennessee State University is working to produce students well prepared to meet this nationwide concern.

“There are several ways in which our department is helping our students enter the workforce in order to make a real-world impact in the …


2023-December-18-Etsu Reports Record $70.4 Million In Sponsored Program And Research Funding.Pdf, University Marketing And Communication, East Tennessee State University Dec 2023

2023-December-18-Etsu Reports Record $70.4 Million In Sponsored Program And Research Funding.Pdf, University Marketing And Communication, East Tennessee State University

ETSU News

From research in rural health to work in the booming field of biotechnology, East Tennessee State University aims to generate scholarship that has a real-world impact both in the region and beyond.

And in the last fiscal year, ETSU earned an impressive $70.4 million in external awards. That funding goes toward pushing major advancements in a range of diverse fields.

“ETSU is certainly known for the immense and engaging hands-on learning experiences we offer our students with a goal of helping them move from enrolled to employed,” said Dr. Kimberly D. McCorkle, ETSU provost and senior vice president for Academic …


Investigating The Geochemical Trends At The Sediment-Water Interface Of The Shallow And Eutrophic Utah Lake, Abidemi Sherif Aremu Dec 2023

Investigating The Geochemical Trends At The Sediment-Water Interface Of The Shallow And Eutrophic Utah Lake, Abidemi Sherif Aremu

Theses and Dissertations

The sources of phosphorus (P) in Utah Lake can be diverse, including natural and anthropogenic point and non-point sources, such as atmospheric deposition, soil erosion, and industrial and urban wastewater effluents. This study collected interface sediments, column water, porewater, and sediment cores across this vast water body. These samples were then analyzed for their mineralogic, organic, and elemental composition to characterize the geochemical nature of water and sediment at the water-sediment interface within Utah Lake. The average concentrations of P and other elements found in the column water of an individual site do not significantly differ across depth suggesting Utah …


Predicting Speaking Proficiency With Fluency Features Using Machine Learning, Ethan D. Erickson Dec 2023

Predicting Speaking Proficiency With Fluency Features Using Machine Learning, Ethan D. Erickson

Theses and Dissertations

This study investigates the interplay between temporal fluency measures, self-assessment, and language proficiency scores in novice- to intermediate- level language learners of Spanish and French. Analyzing data from 163 participants, the research employs both traditional linear regression and advanced XGBoost machine learning models. Findings demonstrate a moderate positive correlation between self-assessment and Oral Proficiency Interview by Computer (OPIc) scores, underscoring the dependable self-awareness of learners. Notably, XGBoost performs as well as linear regression in predicting OPIc scores and has more potential, underlining the efficacy of advanced methodologies. The study identifies Mean Length of Utterance (MLU) as a crucial predictor, highlighting …


Before The Inter-American Court Of Human Rights Written Opinion Regarding The Request For An Advisory Opinion On The Climate Emergency And Human Rights, Francisco J. Rivera Juaristi, Britton Schwartz, Simra Abedi, Rochel Go, Sarah Dávila A., Ámbar Z. Reyes Pérez, Alexis Cortez Dec 2023

Before The Inter-American Court Of Human Rights Written Opinion Regarding The Request For An Advisory Opinion On The Climate Emergency And Human Rights, Francisco J. Rivera Juaristi, Britton Schwartz, Simra Abedi, Rochel Go, Sarah Dávila A., Ámbar Z. Reyes Pérez, Alexis Cortez

Faculty White Papers

No abstract provided.


See "Warhol Revisited" At Uab's Aeiva From Jan. 12-March 16, 2024, Shannon Thomason Dec 2023

See "Warhol Revisited" At Uab's Aeiva From Jan. 12-March 16, 2024, Shannon Thomason

Browse All News

No abstract provided.


L’Evoluzione Della Bella Figura A Tavola Nell'italia Rinascimentale, Lilian Gallardo Dec 2023

L’Evoluzione Della Bella Figura A Tavola Nell'italia Rinascimentale, Lilian Gallardo

Italian Renaissance Foodways

Questo Advanced Integration Project utilizza un approccio sociologico per analizzare l'evoluzione delle maniere nell'Italia rinascimentale, con un focus specifico sull'influenza della classe sociale negli standard di etichetta e in particolare quelli relativi al cibo. Analizzando la transizione dal controllo esterno degli standard di autoregolamentazione interna attraverso lo studio dell’etichetta a tavola, questa ricerca mostra la tavola da pranzo come un luogo in cui affinare e pacificare la società. Lo studio delle maniere nell'Italia del Rinascimento è un riflesso dell'epoca, mostrando come nuovi standard di etichetta emergano da una società sempre più eterogenea. Queste maniere sono un aspetto integrante del processo …


Machine Learning And Metabolic Model Guided Crispri Reveals A Central Role For Phosphoglycerate Mutase In Chlamydia Trachomatis Persistence, Niaz Bahar Chowdhury, Nick Pokorzynski, Elizabeth A. Rucks, Scot P. Ouellette, Rey A. Carabeo, Rajib Saha Dec 2023

Machine Learning And Metabolic Model Guided Crispri Reveals A Central Role For Phosphoglycerate Mutase In Chlamydia Trachomatis Persistence, Niaz Bahar Chowdhury, Nick Pokorzynski, Elizabeth A. Rucks, Scot P. Ouellette, Rey A. Carabeo, Rajib Saha

Department of Chemical and Biomolecular Engineering: Faculty Publications

Upon nutrient starvation, Chlamydia trachomatis serovar L2 (CTL) shifts from its normal growth to a non-replicating form, termed persistence. It is unclear if persistence is an adaptive response or lack of it. To understand that transcriptomics data were collected for nutrientsufficient and nutrient-starved CTL. Applying machine learning approaches on transcriptomics data revealed a global transcriptomic rewiring of CTL under stress conditions without having any global stress regulator. This indicated that CTL’s stress response is due to lack of an adaptive response mechanism. To investigate the impact of this on CTL metabolism, we reconstructed a genome-scale metabolic model of CTL (iCTL278) …


Ndls Communicator: Week Of 12.18.23, Notre Dame Law School Dec 2023

Ndls Communicator: Week Of 12.18.23, Notre Dame Law School

NDLS Communicator

The Latest News

  • Roger Alford testified before the Senate Judiciary Committee last Wednesday on "The New Invisible Hand? The Impact of Algorithms on Competition and Consumer Rights."
  • Randy Kozel has published "Is Chevron Binding Law" in the Yale Journal on Regulation.
  • Carter Snead wrote "The Jurisprudence & Politics of Abortion" for Commonweal in response to Bernard G. Prusak’s recent article “The Pro-Life Movement: Less Popular Than Ever?”
  • Derek Muller was on the Bloomberg Law podcast, "SCOTUS Asked to Rule on Trump Immunity Claims."
  • Stephanie Barclay's article, "The Historical Origins of Judicial Religious Exemptions," was cited in the Virginia Supreme Court's …


How Swiss Authorities Bungled Credit Suisse Oversight, John O'Donnell, Stefania Spezzati, Elisa Martinuzzi Dec 2023

How Swiss Authorities Bungled Credit Suisse Oversight, John O'Donnell, Stefania Spezzati, Elisa Martinuzzi

Documents

No abstract provided.


2023-December-18-Etsu Students Contributing Important Research On Appalachia.Pdf, University Marketing And Communication, East Tennessee State University Dec 2023

2023-December-18-Etsu Students Contributing Important Research On Appalachia.Pdf, University Marketing And Communication, East Tennessee State University

ETSU News

A group of students from East Tennessee State University recently presented a capstone research project in the nation’s capital, examining intersections between economic development and health disparities within underserved and historically Black communities in Washington County, Tennessee.

The group was among 130 students from 13 colleges and universities in 10 Appalachian states participating in the 23rd annual Appalachian Collegiate Research Initiative (ACRI). Sponsored by the Appalachian Regional Commission (ARC), the ACRI capstone symposium is organized by the Center of Excellence for Appalachian Studies and Services at ETSU.

The findings presented by students from ETSU’s Department of Appalachian Studies are from …


Professors’ English-Only Or Multilingual Approaches In English Language Teacher Education At Ecuadorian Universities Dec 2023

Professors’ English-Only Or Multilingual Approaches In English Language Teacher Education At Ecuadorian Universities

Journal of Comparative & International Higher Education

Emerging Scholar


Teacher Retention: Retaining Teachers In High-Needs, Urban Secondary Schools In A Midwest State Post-Pandemic, Christopher K. Schmit, Erin Lehmann, David Swank, Sue Alborn-Yilek, Tasha Dannenbring Dec 2023

Teacher Retention: Retaining Teachers In High-Needs, Urban Secondary Schools In A Midwest State Post-Pandemic, Christopher K. Schmit, Erin Lehmann, David Swank, Sue Alborn-Yilek, Tasha Dannenbring

Journal of Educational Leadership in Action

Teacher retention has been a challenge for most schools for several years. High-needs schools have been known to have twice the trouble with teacher retention as schools not considered high-needs. The purpose of this study was to identify effective practices school principals can implement to retain teachers at high-needs, urban secondary schools. This quantitative study called on teachers from high-needs schools in Iowa to complete a survey identifying principal qualities related to retention, perceived reasons for teacher attrition, and reasons they continue to teach at their current school. Three hundred eighty-five teachers from five different Iowa school districts participated in …


Reviewers And Referees Dec 2023

Reviewers And Referees

Midwest Social Sciences Journal

No abstract provided.


International Graduate Students’ Experiences In Using University Career Services: A Case Study Of A Southern Ontario University, Yilun Jiang Dec 2023

International Graduate Students’ Experiences In Using University Career Services: A Case Study Of A Southern Ontario University, Yilun Jiang

Journal of Comparative & International Higher Education

Emerging Scholars


Optimal Method To Obtain Soil Strength Properties In Sands For Laterally Loaded Pile Analysis In Lpile, Troy Roger Washburn Dec 2023

Optimal Method To Obtain Soil Strength Properties In Sands For Laterally Loaded Pile Analysis In Lpile, Troy Roger Washburn

Theses and Dissertations

One common software program developed for analyzing single laterally loaded piles is called LPILE. Soil properties are required as input into LPILE. For sands, the soil properties required are effective soil unit weight, γ’; subgrade modulus, k; and the internal friction angle, ϕ’. There are two commonly used methods to obtain ϕ’ and subsequently k: the API method and Bolton method. Fourteen different pile test sites were used in the analysis of the API and Bolton methods to obtain soil strength properties in sands for laterally loaded single pile tests. Between the fourteen pile test sites, a total of 26 …


Local Atomic And Magnetic Structure Of Multiferroic (Sr,Ba)(Mn,Ti)O3, Braedon Jones Dec 2023

Local Atomic And Magnetic Structure Of Multiferroic (Sr,Ba)(Mn,Ti)O3, Braedon Jones

Theses and Dissertations

We present a detailed study of the local atomic and magnetic structure of the type-I multiferroic perovskite system (Sr,Ba)(Mn,Ti)O3 using x-ray and neutron pair distribution function (PDF) analysis, polarized neutron scattering, and muon spin relaxation (μSR) techniques. The atomic PDF analysis reveals widespread nanoscale tetragonal distortions of the crystal structure even in the paraelectric phase with average cubic symmetry, corresponding to incipient ferroelectricity in the local structure. Magnetic PDF analysis, polarized neutron scattering, and μSR likewise confirm the presence of short-range antiferromagnetic correlations in the paramagnetic state, which grow in magnitude as the temperature approaches the magnetic transition. We show …


Mechanical Characterization Of Vertically Aligned Carbon Nanotube Forest Microelectrodes For Neural Interfacing, Spencer Mcleod Roberts Dec 2023

Mechanical Characterization Of Vertically Aligned Carbon Nanotube Forest Microelectrodes For Neural Interfacing, Spencer Mcleod Roberts

Theses and Dissertations

Silicon intracortical microelectrodes arrays (MEA) provide some of the best performance for brain computer interfaces but suffer from lifetime limitations that prevent clinical adoption. A primary contributor of lifetime limitations is the chronic foreign body response (FBR) which remains active in response to the brain tissue strain caused by implanted probes during brain micromotion. Designing probes with softer materials can reduce the chronic FBR and improve device lifetime. A high-aspect ratio CNT MEA could provide several advantages as an intracortical MEA but has yet to be mechanically characterized. CNT MEAs are infiltrated with 3 degrees of carbon infiltration and mechanically …


An Investigation Of The Impact Of Prosocial Action On Psychological Resilience In Female Volunteer Maskmakers During Covid-19, Linda D. Montano Dec 2023

An Investigation Of The Impact Of Prosocial Action On Psychological Resilience In Female Volunteer Maskmakers During Covid-19, Linda D. Montano

Industrial-Organizational Psychology Dissertations

Building and maintaining psychological resilience is important because it mediates the impact of stress on life outcomes such as depression, life satisfaction, and well-being. The purpose of this dissertation was to assess the impact of prosocial action as a way to enhance resilience and reduce the impact of adversity. Using 12 waves of longitudinal data collected from 86 female volunteer maskmakers in the U.S. between April and July 2020, this study assessed the hypothesis that the prosocial action of maskmaking will moderate the impact of the stress of the COVID-19 pandemic such that at higher levels of maskmaking, the volunteer’s …


Reclaiming Sacred Homelands: Asserting Treaty Rights And The Path Towards Restoration Of The Badger-Two Medicine, Sarah Greenberg Dec 2023

Reclaiming Sacred Homelands: Asserting Treaty Rights And The Path Towards Restoration Of The Badger-Two Medicine, Sarah Greenberg

American Indian Law Journal

“In order for law to have an influence in the lives of ordinary people, it must have something to do with the emotional feelings of justice, it must speak to our basic humanity, and it must give us common sense directions as to what behavior and beliefs are right and wrong"


Motives And Methodologies For Improving 3d Displays, Dylan Charles Barton Dec 2023

Motives And Methodologies For Improving 3d Displays, Dylan Charles Barton

Theses and Dissertations

This work contains two key contributions to the development of 3D displays. First a successful exploratory human trial research study. By comparing multiple real displays in human trials, the factors of ease of use, time, and accuracy were able to be examined in a general setting, instead of isolated to only a specific type of 3D display. These human tests showed that 3D displays in general offer better ease of use and accuracy compared to 2D displays when showing 3D media. This differs from previous studies where only a single display was examined or theoretical papers discussing factors on paper. …


Simulating Government Institutions In Networked Societies, Michael Richards Dec 2023

Simulating Government Institutions In Networked Societies, Michael Richards

Theses and Dissertations

Modern human societies give rise to the expression of complex group dynamics between the members of said society due to the abundance of continued interactions. Of particular interest are how institutions affect these interactions between societal members, alter the resulting group dynamics, and impact society as a whole through their rules. Simulating these dynamics allows for greater insight into how these institutions function and allows researchers to pose interesting questions and test hypotheses within a laboratory setting. We present a novel approach to simulating institutions, particularly governments, within a networked society. This approach builds upon the Junior High Game, which …


Characterization Of Friction At The Tool/Material Interface In Friction Stir Welding, Bryan Gonzalo Ramos Gonzales Dec 2023

Characterization Of Friction At The Tool/Material Interface In Friction Stir Welding, Bryan Gonzalo Ramos Gonzales

Theses and Dissertations

Friction Stir Welding (FSW) process development is very costly, and it is still experimental. A predictive model would optimize the weld by changing parameters and obtaining results that reflect the physical process. Friction is the primary adjustable parameter in FSW modeling. Currently, friction model selection is not physic-based. It is based on what is available and contributes to the best fit between the model and experimental data. The research objective is to characterize the interface tool/base material by studying the effect of tool friction coefficient and thermal properties. This is accomplished by changing welding parameters such as force, rpm, and …


Value And Impact Of Nurse Innovators Working In Academic, Industry, And Government Settings: A Qualitative Study, Olivia A. Lemberger Dec 2023

Value And Impact Of Nurse Innovators Working In Academic, Industry, And Government Settings: A Qualitative Study, Olivia A. Lemberger

Dissertations

This dissertation explores the value and impact of nurse innovators working in academic, industry, and government settings. A qualitative descriptive study was chosen to understand the contributions of nurse innovators and the outcomes associated with their innovative endeavors. The purpose of this study is to better understand the contributions of nurse innovators by answering the following research questions: 1) How do nurses perceive that nursing innovation adds value to and/or impacts patients or the United States health care system? 2) What metrics/outcome measures do nurse innovators identify as relevant or useful to evaluate innovation success? And 3) What methods/resources do …


Ddx219.3 Social Media Content Creation Example 1, Sae University College Dec 2023

Ddx219.3 Social Media Content Creation Example 1, Sae University College

Exemplars

Social Media Marketing and Content Creation