Digital Commons Network^™

Targeting Mitochondrial Dysfunction Using Methylene Blue Or Mitoquinone To Improve Skeletal Aging., Sher Bahadur Poudel, Dorra Frikha-Benayed, Ryan R Ruff, Gozde Yildirim, Manisha Dixit, Ron Korstanje, Laura Robinson, Richard A Miller, David E Harrison, John R Strong, Mitchell B Schaffler, Shoshana Yakar

Faculty Research 2024

Methylene blue (MB) is a well-established antioxidant that has been shown to improve mitochondrial function in both in vitro and in vivo settings. Mitoquinone (MitoQ) is a selective antioxidant that specifically targets mitochondria and effectively reduces the accumulation of reactive oxygen species. To investigate the effect of long-term administration of MB on skeletal morphology, we administered MB to aged (18 months old) female C57BL/J6 mice, as well as to adult male and female mice with a genetically diverse background (UM-HET3). Additionally, we used MitoQ as an alternative approach to target mitochondrial oxidative stress during aging in adult female and male …

Elementary Summer School: Culturally Responsive Practices And Academic Outcomes For English Learner Students In Grades 4–6, Laurie May Virtusio

LMU Theses and Dissertations

This mixed-method study explored the culturally responsive practices of a midsized, Southern California school district that used Expanded Learning Opportunities Program (ELOP) state funding to implement a voluntary summer program accessible to TK–6 grade students district-wide. Qualitative data gathered from semistructured interviews with the principal on special assignment (POSA), three upper-grade summer school teachers, and three school outreach liaisons (SOLs) highlighted the culturally responsive practices of the school district to address student and family needs, focusing specifically on English learners (ELs). Quantitative data from the school district examined included the summative test scores for EL students in Grades 4–6. Although …

Transformational Experiences And Decision-Making Processes: Factors Influencing The Choice Of College Major, Ashley Hunsaker

Undergraduate Honors Theses

This thesis examines the influence of transformational experiences on decision making when it comes to choosing one’s major. Participants attended a one-on-one interview with the primary researcher where questions were asked about how they chose their major and how much they enjoy it. Participants were given the chance to tell stories about how they discovered their major and how they decided to pursue it. Results suggested that transformational experiences, internal and external factors, and mentorship led students to choose and stick with a major where they felt a sense of belonging and “fit.” When belonging and perceived fit were not …

Exploring Geological Parameters Sensitive To Underground Coal Gasification, Zhou Ze, Yi Tongsheng, Qin Yong, Zhou Yongfeng, Wang Lingxia, Kong Weimin

Coal Geology & Exploration

Compared to ground coal chemical plants, underground coal gasification (UCG) requires gasifiers as geological bodies. Accurately understanding geological conditions is a critical prerequisite for UCG. To minimize the geological risks involved in UCG siting, this study systematically explored the geological parameters sensitive to UCG based on the intricate geological conditions of Guizhou Province, China. By collecting and organizing the exploration data of coal resources in Guizhou, this study established mathematical models for normalized, graded parameter value assignment, the algorithm of parameter weight vectors, and the algorithm of parameter weight product, with the purpose of obtaining the accurate quantitative data of …

Uranium And Thorium Enrichment Characteristics Of Bauxite In Coal Measure Strata And Their Natural Gamma-Ray Responses, Zhang Xiaohui, Zhang Shangqing, Liu Dongna, Zhao Fenghua, Zhao Jun, Zhong Zhuanghua, Hou Xuqin

Coal Geology & Exploration

Shanxi Province boasts abundant bauxite resources occurring in coal measure strata, with the deep bauxite resources in this province subjected to progressive assessment. This study aims to further determine the endowment of aluminum resources within coals in the province and explore efficient exploration methods. To this end, this study investigated the bauxite layers in Upper Carboniferous coal measure strata in the Xiaoyi area, Shanxi Province. It examined 37 samples from three boreholes using methods such as optical microscopy, X-ray diffraction (XRD), scanning electron microscopy (SEM), X-ray fluorescence spectrometry (XRF), and inductively coupled plasma mass spectrometry (ICP-MS). Based on the analysis …

Law Governing Variations In Water-Pressure Transmission Rate In Confined Aquifers, Wang Wenxue, Wang Bosen, Gao Yanwei, Wu Bing, Nie Tianyu

Coal Geology & Exploration

The water pressure in aquifers is transmitted as energy, with a transmission rate much higher than the migration rate of water particles. The water-pressure transmission rate holds great significance for the safe construction and disaster forecast and prediction of underground engineering under high-pressure water aquifers and bodies. Focusing on the confined aquifers bearing no cohesive soil, this study explored the law governing the changes in the water-pressure transmission rate through theoretical analysis, numerical simulations, field experiments, and laboratory physical model tests. Key findings are as follows: (1) The transmission of water-pressure changes in the aquifers exhibited noticeable hysteresis. The transmission …

Coal-Rock Interface Imaging Based On Acoustic Remote Reflection Logging Within Crossing Boreholes Using The Finite Element Method, Xu Hongyang, Zhai Cheng, Xia Jigen, Sun Yong, Dong Xingmeng, Lai Yongshuai, Yu Xu, Xu Jizhao, Cong Yuzhou

Coal Geology & Exploration

The presence of small geological structures is the main cause of coal and gas outbursts, making the precise detection of these structures an urgent need. High-precision detection of coal-rock interfaces is essential for identifying small structures and achieving transparent mining faces. The acoustic remote reflection logging technology, with a large detection range, a high resolution, and imaging capability, can accurately identify coal-rock interfaces. In this context, this study proposed a technique for coal-rock interface detection based on acoustic remote reflection logging within crossing boreholes. Specially, by placing acoustic detectors in crossing boreholes, the array waveforms generated by the coal-rock interfaces …

18th Annual Research In The Capitol [Program], March 25, 2024, University Of Northern Iowa. University Honors Program. Iowa State University. Honors Program. University Of Iowa. Honors Program.

Research in the Capitol Programs

Program of research presentations given at the Capitol by students from the University of Northern Iowa, Iowa State University, and the University of Iowa.

Investigating Channel Narrowing And Nonnative Vegetation Encroachment In Three Dryland Rivers, Casey Pennock, Benjamin Miller, Phaedra Budy

Browse all Datasets

Water development and the proliferation of invasive riparian vegetation has led to widespread habitat loss and simplification of rivers in the western United States, contributing to the imperilment of native fishes. Here, we quantify channel narrowing and vegetation encroachment, which are conspicuous indicators of riverine habitat degradation, along approximately 400 km of three dryland tributaries of the upper Colorado River. To accomplish this, we conducted a comparative analysis of aerial photographs from historical (1930s) and contemporary (2010s or 2020s) time periods and utilized Light Detection and Ranging (LiDAR) data and Object-Based Image Analysis (OBIA) to determine contemporary canopy cover of …

Preserving Linguistic Diversity In The Digital Age: A Scalable Model For Cultural Heritage Continuity, James Hutson, Pace Ellsworth, Matt Ellsworth

Faculty Scholarship

In the face of the rapid erosion of both tangible and intangible cultural heritage globally, the urgency for effective, wide-ranging preservation methods has never been greater. Traditional approaches in cultural preservation often focus narrowly on specific niches, overlooking the broader cultural tapestry, particularly the preservation of everyday cultural elements. This article addresses this critical gap by advocating for a comprehensive, scalable model for cultural preservation that leverages machine learning and big data analytics. This model aims to document and archive a diverse range of cultural artifacts, encompassing both extraordinary and mundane aspects of heritage. A central issue highlighted in the …

Factorization In Cybersecurity: A Dual Role Of Defense And Vulnerability In The Age Of Quantum Computing, Himateja Arukala

Theses and Dissertations

One of the most critical components of modern cryptography and thus cybersecurity is the ability to factor large integers quickly and efficiently. RSA encryption, one of the most used types, is based largely on the assumption that factoring for large numbers is computationally infeasible for humans and computers alike. However, with quantum computers, people can use an algorithm like Shor’s algorithm to perform the same task exponentially faster than any normal device ever could. This investigation will go into the strength and vulnerability of RSA encryption using the power of factorization in an age of quantum computers.We start by looking …

Road Maintenance Through Machine Learning, Yashwanth Sai Rachala

Theses and Dissertations

This thesis explores the use of machine learning techniques for road infrastructure maintenance. We propose an innovative machine learning-based approach to improve the efficiency and effectiveness of road maintenance strategies. The focal point of this investigation is the development and implementation of a machine learning framework to enhance road quality monitoring. We use Long Short-Term Memory (LSTM) networks to accurately predict future road conditions and identify potential areas requiring maintenance before significant deterioration occurs. This predictive approach is designed to enable a shift from reactive to proactive road maintenance, optimizing the use of limited resources and improving overall road safety. …

Application Of The Horizontal Seismic Profiling-Based Advance Detection Technology To The Excavation Of Rock Roadways In Coal Mines Using Tunnel Boring Machines, Zhang Sheng, Chen Zhao, Lu Song, Yang Zhanbiao, Ji Panjun, He Fei, Lu Yiqiang, Liu Jiawei

Coal Geology & Exploration

With the gradual application of full-face tunnel boring machines (TBMs) to the excavation of rock roadways in coal mines, there is an increasingly urgent need for the accurate and rapid advance prediction of unfavorable geological structures. This study analyzed the characteristics of active-source seismic wave-based advance detection methods and the applicability of the advance detection technology based on TBM seismic while drilling (TSWD) with TBM rock-breaking vibration as a seismic source. Then, by combining the geological and production conditions of coal mine roadways, this study proposed a horizontal seismic profiling (HSP)-based advance detection method applicable to the excavation of roadways …

Early Warning And Prediction Of Kicks And Lost Circulation Accident During Rescue Drilling Of Mine, Chen Weiming, Wang Jiawen, Fan Dong, Hao Shijun, Zhao Jiangpeng, Qiu Yu

Coal Geology & Exploration

In order to solve the problems such as the difficulty in early warning and prediction of kicks and lost circulation accidents during emergency rescue drilling of mine, a machine learning-based early for warning and prediction model of drilling process was established. Firstly, the accident characterization parameters of the drilling parameters in the early stage of kicks and lost circulation accidents were analyzed. Secondly, the accident characterization parameters were cleaned and processed. On this basis, XGBoost and early warning model was used to carry out the early diagnosis and identification of kicks and lost circulation accidents. Then, the PSO-LSTM accident development …

Analysis On Working Characteristics Of Cam-Roller Impact Mechanism Of Rotary Percussion Drilling Tool, Sun Yangqing, Yi Xianzhong, Wan Jifang, Ma Jianqi, Wu Jiwei, Yi Jun, Yin Guangpin

Coal Geology & Exploration

Rotary percussion drilling tools can effectively improve their rock breaking efficiency in the deep and hard strata, thus having broad application prospects. The cam-roller is the key mechanism to realize the impact action, but the complex and changeable downhole environment leads to serious damage to the mechanism, which in turn affects the efficiency of rock breaking. Based on the test drilling data of rotary impact drilling tools in several wells, the cam-roller dynamics model was established, the working characteristics under different strokes, speeds and drilling pressures were analyzed by Autodyn (explicit dynamics), and the deformation characteristics of the mechanism were …

Development And Application Of An Automatic Online Testing Instrument For The Funnel Viscosity And Density Of Drilling Fluids, Xie Hui, Zheng Liqun, Liu Fulin, Liang Mengjia, Liu Xuan, Cai Jihua, Yang Xianyu, Hou Jiwu

Coal Geology & Exploration

In recent years, the research on the automatic performance testing technology for drilling fluids has achieved significant progress both domestically and internationally. However, automatic drilling fluid testing instruments face challenges, such as high costs, complicated structures, and restricted working environments. Given these challenges, this study developed an automatic online testing instrument for the funnel viscosity and density of drilling fluids. The testing instrument consists of mud pumping, testing, cleaning, and control modules, which are built using a programmable logic controller (PLC), an Internet of things (IoT) module, a pressure sensor, an ultrasonic sensor, a peristaltic mud pump, an electric ball …

Deformation And Collapse Patterns Of Gas Drainage Boreholes And A Precise Monitoring Technology, Xiao Peng, Huang Xiaosheng, Liu Xiaoxiao, Li Bingkun, Chen Liping, Chen Zixi, Zhang Chao, Cheng Renhui, Zhao Yajie

Coal Geology & Exploration

This study aims to promote the precise and intelligent monitoring of gas drainage boreholes. In the engineering background of a coal mine in Shanxi Province, this study conducted simulation experiments on the plugging of gas extraction boreholes under varying particle size ratios of simulated coal samples using distributed optical fiber monitoring and the Brillouin Optical Time-Domain Analysis (BOTDA). Then, this study established a mathematical model for calculating the borehole plugging rate of the test mine, revealing the deformation and collapse patterns of gas drainage boreholes. Furthermore, this study proposed a precise in-situ monitoring technology for the gas drainage boreholes in …

An Experimental Study Of Factors Influencing Gas Seepage In Confined Broken Anthracite, Li Zhen, Yu Yirui, Wang Hongwei, Feng Guorui, He Fulian, Wang Dezhang, Zhou Jinhui, Liu Luyan, Han Xinlei

Coal Geology & Exploration

The void structure evolution of broken coals in a caving zone directly affects the gas seepage characteristics of the zone, further influencing the gas migration and enrichment patterns in abandoned coal mine goaves. With the second generation of compaction-seepage-CT scanning experimental system for broken coals independently designed and developed, this study performed 162 sets of permeability experiments on broken anthracite samples with five particle size ranges under varying gas pressures, axial stresses, and void fractions. Key findings are as follows: (1) When gas migrated in broken anthracite, its pressure and flow rate kept dynamically changing until the adsorption equilibrium was …

Positioning Error Compensation Of Drilling Robot Arm For Coal Mine, Liang Chunmiao, Yao Ningping, Yao Yafeng, Peng Tao

Coal Geology & Exploration

At present, the pose of drilling robots is mostly adjusted by manual remote control and manual retest in combination. Full automatic adjustment has not been achieved. Besides, due to the low precision of open-loop control and inadequate automation capability, the accurate hole positioning and automatic construction of hole groups cannot be realized by drilling robots with water exploration and discharge, outburst prevention and punching prevention in coal mines. Herein, the kinematic model of drilling arm was established by analyzing the structure and action of the drilling robot’s drilling arm. Meanwhile, the dip angle factors such as machining error, body deformation …

Operation Process Identification For Intelligent Drill Rig Base On Analytic Hierarchy Process, Zhu Qianxiang, Luo Pengping, Wang Longpeng, Xing Wang, Wang Tianlong

Coal Geology & Exploration

It is very difficult to automatically identify the current process during the intelligent construction of coal mine drill rigs. In response to this, an operation process identification method was proposed, which includes hierarchical modeling of drill rig operation and probability inference of process execution. Firstly, the coupling process among the components of different granularity during the operation of drill rig is described and modeled based on the hierarchical analysis method, which reveals the interactive characteristics between equipment, function and system during the execution of each process. Secondly, Bayesian probabilistic reasoning method is introduced based on the above research to establish …

Improving Medical Image Classification Accuracy Through Unsupervised Segmentation And Confounder Mitigation With Limited Data, Nikolai Fetisov

USF Tampa Graduate Theses and Dissertations

Medical images are indispensable for assisting health care professionals to make more accurate cancer diagnosis and prognosis decisions. Several image modalities exist including, but not limited to, histopathology or whole slide images (WSI), computed tomography (CT), positron emission tomography (PET) and radiography (i.e., X-Ray), each having their own application in clinical practice.

Today, machine learning and deep learning methods have evolved to the point of being practically usable. These approaches learn and extract knowledge from data to make possible automating certain tasks. At the point of writing this dissertation, they have reached human-level performance in general image recognition tasks, became …

Lrs: Enhancing Adversarial Transferability Through Lipschitz Regularized Surrogate, Tao Wu, Tony Tie Luo, Donald C. Wunsch

Computer Science Faculty Research & Creative Works

The Transferability of Adversarial Examples is of Central Importance to Transfer-Based Black-Box Adversarial Attacks. Previous Works for Generating Transferable Adversarial Examples Focus on Attacking Given Pretrained Surrogate Models While the Connections between Surrogate Models and Adversarial Trasferability Have Been overlooked. in This Paper, We Propose Lipschitz Regularized Surrogate (LRS) for Transfer-Based Black-Box Attacks, a Novel Approach that Transforms Surrogate Models towards Favorable Adversarial Transferability. using Such Transformed Surrogate Models, Any Existing Transfer-Based Black-Box Attack Can Run Without Any Change, Yet Achieving Much Better Performance. Specifically, We Impose Lipschitz Regularization on the Loss Landscape of Surrogate Models to Enable a Smoother …

Size Limits And Fission Channels Of Doubly Charged Noble Gas Clusters, Ianessa Stromberg, Stefan Bergmeister, Lisa Ganner, Fabio Zappa, Paul Scheier, Olof Echt, Elisabeth Gruber

Faculty Publications

Small, highly charged liquid droplets are unstable with respect to spontaneous charge separation when their size drops below the Rayleigh limit or, in other words, their fissility parameter X exceeds the value 1. The absence of small doubly charged atomic cluster ions in mass spectra below an element-specific appearance size n_a has sometimes been attributed to the onset of barrierless fission at X = 1. However, more realistic models suggest that n_a marks the size below which the rate of fission surpasses that of competing dissociative channels, and the Rayleigh limit of doubly charged van der Waals clusters …

Epa Remedial Project Manager Change, Berkeley Pit/Mine Flooding Operable Unit (Bmfou) Of The Silver Bow Creek/Butte Area And Consent Decree For The Mine Flooding Site, Cv 02-35-Bu-Rfc, Jason Rappe

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Selective Vapor Condensation For The Synthesis And Assembly Of Spherical Colloids With A Precise Rough Patch, Kennedy A. Guillot, Philip J. Brahana, Ahmed Al Harraq, Nduka D. Ogbonna, Nicholas S. Lombardo, Jimmy Lawrence, Yaxin An, Michael G. Benton, Bhuvnesh Bharti

Faculty Publications

Patchy particles occupy an increasingly important space in soft matter research due to their ability to assemble into intricate phases and states. Being able to fine-tune the interactions among these particles is essential to understanding the principles governing the self-assembly processes. However, current fabrication techniques often yield patches that deviate chemically and physically from the native particles, impeding the identification of the driving forces behind self-assembly. To overcome this challenge, we propose a new approach to synthesizing spherical colloids with a well-defined rough patch on their surface. By treating polystyrene microspheres with vapors of a good solvent, here an acetone-water …

03.25.2024 Orsp Connect, Liz Williamson

ORED Newsletter

Cammi Thornton, Compliance Training Requirements

Tamara Lee Powell, Appellant V. Dean Deloy Powell, Appellee : Brief Of Appellant, Utah Court Of Appeals

Utah Court of Appeals Briefs (2020 –)

Appeal from a Judgment of the Third Judicial District Court Salt Lake County, Honorable Mark Kouris

Dennis R. James, Attorney for Appellant

David Corbett, Attorney for Appellee

Toward Local Madelung Mechanics In Spacetime, Mordecai Waegell

Mathematics, Physics, and Computer Science Faculty Articles and Research

It has recently been shown that relativistic quantum theory leads to a local interpretation of quantum mechanics wherein the universal wavefunction in configuration space is entirely replaced with an ensemble of local fluid equations in spacetime. For want of a fully relativistic quantum fluid treatment, we develop a model using the nonrelativistic Madelung equations, and obtain conditions for them to be local in spacetime. Every particle in the Madelung fluid is equally real, and has a definite position, momentum, kinetic energy, and potential energy. These are obtained by defining quantum momentum and kinetic energy densities for the fluid and separating …

A Method For Coal Seam Pressure Relief Based On Steel Cone Impact, Ren Zhimin, Lyu Mengjiao, Wang Fei, Wang Yu, Zhang Guangtai

Coal Geology & Exploration

This study aims to solve the mining safety problems caused by rock bursts in coal mines. With the geological mining conditions of the No.3 coal seam in the Wulihou coal mine in Zuoquan County, Jinzhong City, Shanxi Province as the engineering background, this study proposed a method for coal seam pressure relief based on steel cone impact. Specifically, based on the electromagnetic repulsion generated between energized coils, this study derived the functions of impact force produced when a magnetically driven coil-wound steel cone impacted the coal seam. Combining the theory on elastic mechanics, this study analyzed the stress field distribution, …

Two-Phase Flow Chokeling Results And Control In High-Pressure Gas Wells Producing Water, Liu Xinfu, Liu Chunhua, Li Qingping, Yao Haiyuan, Hao Zhongxian, Liu Yongfei

Coal Geology & Exploration

Prediction and control of two-phase flow chokeling in tight gas wellbores are essential for the normal operation and hydrate control of high-pressure gas wells producing water. The thermodynamic differential equations of energy, kinetic energy and temperature and models of chokeling field for two-phase energy, system heat, mass balance and flow were developed under the conditions of isentropic adiabatic, isobaric heat capacity, constant volume heat capacity, and chokeling energy. A methodology on predicting characteristics and control of two-phase flow before and after chokeling was proposed for gas-water two phase flow. It provided a theoretical basis for optimizing the structural parameters of …