Digital Commons Network^™

The Role Of Efflux Pump Inhibitor In Enhancing Antimicrobial Efficiency Of Silver Nanoparticles And Methylene Blue As An Effective Photodynamic Therapy Agent, Yaran Allamyradov

Masters Theses & Specialist Projects

Efflux pumps are critical active transport systems utilized by cells to expel toxic substances, including antibiotics and photosensitizer complexes, thereby contributing to antimicrobial resistance. Efflux pump inhibitors (EPIs), which are compounds that obstruct the transport of molecules through these pumps, play a pivotal role in enhancing the effectiveness of antimicrobial therapies against pathogens. This study investigates the effects of the EPI reserpine on the photodeactivation rate of pathogens when used in conjunction with silver nanoparticles (Ag NPs) and methylene blue (MB), a common photosensitizer.

Our research reveals that the application of reserpine, in combination with Ag NPs and MB, leads …

Evaluating Stormwater Erosion Prevention And Sediment Control Best Management Practices Using High-Resolution Rainfall Monitoring And Field-Based Assessment Tools, Brittany Pekara

Masters Theses & Specialist Projects

Advancing stormwater management methods and technology is critical as runoff from impermeable surfaces increases with urbanization and development. Stormwater runoff is highly susceptible to contamination from non-point source pollution and causing flood impacts following rain events, which varies spatially and temporally in an urban landscape. To counteract the impacts of contamination and drainage issues, Best Management Practices (BMPs) are implemented to reduce the effects of stormwater runoff; however, the unpredictable nature of storm events can make methods for effectively monitoring impacts difficult in trying to capture first flush inputs, flood threats, and sedimentation sources. This research utilizes a highresolution rainfall …

Factors Influencing Teacher Retention In K-12 Public Schools In Rural Hawai’I As Perceived By K-12 Public School Teachers, Celeste Akiu

Dissertations

Purpose. This qualitative study aimed to identify and describe the factors influencing teacher retention in K-12 public schools in rural Hawai’i, as perceived by K-12 public school teachers examined within the framework of Mason and Matas’ (2015) conceptualization of four capital factors: human, social, structural, and positive psychological. Methodology. This qualitative study intended to identify factors that influenced teachers in rural Hawai’ian communities to remain in the profession. Convenience purposeful sampling was used to identify the nine teachers who participated in this study. The Four Capital Framework for Teacher Retention was used to guide the questions used in the interviews, …

What If The Resulting Interval Is Too Wide: From A Heuristic Fuzzy-Technique Idea To A Mathematically Justified Approach, Marc Fina, Vladik Kreinovich

Departmental Technical Reports (CS)

In engineering designs, we usually need to make sure that the values of some characteristics y do not exceed a certain threshold y0 – e.g., that the stress at each location does not exceed a certain critical value. Usually, we know how each of these characteristics y depends on the design parameters x1, . . . ,xn, i.e., we know the function y= f (x1, . . . ,xn). However, it is not enough to use the nominal values of the design parameters in our analysis, since the actual values are, in general, somewhat different from the nominal values. Often, …

Effects Of Perceptions Of Forest Change And Intergroup Competition On Community-Based Conservation Behaviors, Matt Clark, Haji Masoud Hamad, Jeffrey Andrews, Vicken Hillis

Human-Environment Systems Research Center Faculty Publications and Presentations

Approximately one quarter of the earth's population directly harvests natural resources to meet their daily needs. These individuals are disproportionately required to alter their behaviors in response to increasing climatic variability and global biodiversity loss. Much of the ever-ambitious global conservation agenda relies on the voluntary uptake of conservation behaviors in such populations. Thus, it is critical to understand how such individuals perceive environmental change and use conservation practices as a tool to protect their well-being. We developed a participatory mapping activity to elicit spatially explicit perceptions of forest change and its drivers across 43 mangrove-dependent communities in Pemba, Tanzania. …

Maximal Estimates For The ∂-Neumann Problem On Non-Pseudoconvex Domains, Phillip S. Harrington, Andrew Raich

Mathematical Sciences Faculty Publications and Presentations

It is well known that elliptic estimates fail for the ∂-Neumann problem. Instead, the best that one can hope for is that derivatives in every direction but one can be estimated by the associated Dirichlet form, and when this happens, we say that the ∂-Neumann problem satisfies maximal estimates. In the pseudoconvex case, a necessary and sufficient geometric condition for maximal estimates has been derived by Derridj (for (0, 1)-forms) and Ben Moussa (for (0, q)-forms when q ≥ 1). In this paper, we explore necessary conditions and sufficient conditions for maximal estimates in the non-pseudoconvex case. We also …

Settingsorder Article Reprints Open Accessarticle A Model To Account For The Effects Of Load Ratio And Hydrogen Pressure On The Fatigue Crack Growth Behavior Of Pressure Vessel Steels, Ashok Saxena, Kip O. Findley

Mechanical Engineering Faculty Publications and Presentations

A phenomenological model for estimating the effects of load ratio R and hydrogen pressure P_H2 on the hydrogen-assisted fatigue crack growth rate (HA-FCGR) behavior in the transient and steady-state regimes of pressure vessel steels is described. The "transient regime" is identified with crack growth within a severely embrittled zone of intense plasticity at the crack tip. The "steady-state" behavior is associated with the crack growing into a region of comparatively lower hydrogen concentration located further away from the crack tip. The model treats the effects of R and P_H2 as being functionally separable. In the transient …

Mesenchymal Stem Cells In Autoimmune Disease: A Systematic Review And Meta-Analysis Of Pre-Clinical Studies, Hailey N. Swain, Parker D. Boyce, Bradley A. Bromet, Kaiden Barozinksy, Lacy Hance, Dakota Shields, Gayla R. Olbricht, Julie A. Semon

Mathematics and Statistics Faculty Research & Creative Works

Mesenchymal Stem Cells (MSCs) Are of Interest in the Clinic Because of their Immunomodulation Capabilities, Capacity to Act Upstream of Inflammation, and Ability to Sense Metabolic Environments. in Standard Physiologic Conditions, They Play a Role in Maintaining the Homeostasis of Tissues and Organs; However, there is Evidence that They Can Contribute to Some Autoimmune Diseases. Gaining a Deeper Understanding of the Factors that Transition MSCs from their Physiological Function to a Pathological Role in their Native Environment, and Elucidating Mechanisms that Reduce their Therapeutic Relevance in Regenerative Medicine, is Essential. We Conducted a Systematic Review and Meta-Analysis of Human MSCs …

Surface Patterning On Zirconia Dental Implants Via Laser-Induced Shockwave Imprinting, Inomjon Majidov

Masters Theses & Specialist Projects

Zirconia is rapidly becoming a preferred alternative to titanium in dental applications, primarily due to its aesthetic resemblance to natural teeth. This material’s tooth-like color avoids the aesthetic issues associated with the grey metal tint of titanium implants. Additionally, zirconia is hypoallergenic, making it an ideal choice for patients with metal sensitivities or allergies. Despite these advantages, zirconia generally exhibits lower biocompatibility and osseointegration compared to titanium implants. This study investigates laser-assisted, controlled imprinting technique on zirconia surfaces to enhance these properties. Our research used zirconia pellets, produced from powdered monoclinic zirconia pressed in a pellet press machine. Two methods …

Skyscrapers, Liza Bondurant

CoE Publications

No abstract provided.

Untapped Potential? Understanding The Paraeducator-To-Teacher Pipeline And Its Potential For Diversifying The Teacher Workforce, Andrew M. Camp, Gema Zamarro, Josh B. Mcgee

Education Reform Faculty and Graduate Students Publications

Paraeducators are among the largest categories of public education employees and are increasingly seen as a pool of potential teachers. However, little is known about paraeducator-to-teacher transitions. Using statewide administrative data, we show that while paraeducators may be more racially/ethnically diverse than the teacher workforce, Black and Hispanic paraeducators are less likely than White paraeducators to transition into teaching. We additionally show that teachers with paraeducator experience are similarly effective to teachers without paraeducator experience. Lastly, we use simulations to show that the potential for the paraeducator-to-teacher pipeline to diversify the teaching profession may be limited unless they are highly …

Rotary Spading To Ameliorate Soil Water Repellence, Department Of Primary Industries And Regional Development, Western Australia

Natural resources factsheets

One-off deep cultivation can reduce the severity of soil water repellence by mixing some of the repellent topsoil into the wettable subsoil and bringing wettable subsoil to the surface.

Rotary spading or deep cultivation increases water infiltration by providing pathways for water entry; diluting the water repellent soil with non-repellent soil; increasing the breakdown of soil organic matter causing water repellence; in some soil types, spading and other deep cultivation can lift subsoil with higher clay content to the surface.

Deep cultivation increases the risk of wind and water erosion. To minimise the risk of erosion, follow the guidelines on …

An Efficient Neutrosophic Approach For Evaluating Possible Industry 5.0 Enablers In Consumer Electronics: A Case Study, Mai Mohamed, Asmaa Elsayed, Bilal Arain, Jun Ye

Neutrosophic Systems with Applications

With the use of cutting-edge technologies like artificial intelligence (AI), robotics, and the Internet of Things (IoT), Industry 5.0 represents a breakthrough move towards a sustainable and human-centered industrial future. Industry 5.0 endeavors to transform industries such as consumer electronics by emphasizing sustainability and collaboration, in contrast to its predecessors, who only concentrated on automation and efficiency. Along with improved manufacturing efficiency and product innovation, this change in the consumer electronics sector also redefines the human-machine interaction. This paper proposes a novel hybrid integrating model that combines the Entropy Weight Method (EWM), Best-Worst Method (BWM), and an acronym in Portuguese …

Cubic Soft Ideals On B-Algebra For Solving Complex Problems: Trend Analysis, Proofs, Improvements, And Applications, Muhammad Saeed, Hafiz Inam Ul Haq, Mubashir Ali

Neutrosophic Systems with Applications

In this paper, we introduce the concepts of cubic soft (CS) algebra, CS o-subalgebra, and CS ideals within the framework of B-algebra. We provide comprehensive characterizations of these new structures, elucidating their unique properties and interrelationships. Specifically, we present detailed conditions under which a CS subalgebra can be classified as a closed CS ideal. Our analysis explores the intricate relationships among closed cubic soft ideals, cubic soft subalgebras, and cubic soft o-subalgebras. By doing so, we aim to provide a deeper understanding of how these structures interact and coexist within the broader context of B-algebra The findings offer significant insights …

Divergence Measures And Aggregation Operators For Single-Valued Neutrosophic Sets With Applications In Decision-Making Problems, Surender Singh, Sonam Sharma

Neutrosophic Systems with Applications

Single-valued neutrosophic sets (SVNSs) facilitate the representation of uncertain information more extensively than conventional methods. The study of divergence measures of SVNSs is important due to their applications in different areas like multi-criteria decision-making (MCDM), pattern recognition, cluster analysis, machine learning, etc., In this paper, we introduce a divergence measure for SVNSs. The suggested divergence measure is applied to cluster analysis for the classification of imprecise data. For establishing the reasonability and advantage of the suggested divergence measure in a clustering problem over the existing measures, a comparative assessment is also presented. Furthermore, we introduce, an inferior ratio method for …

Stimuli-Responsive Phosphate Hydrogel: A Study On Swelling Behavior, Mechanical Properties, And Application In Expansion Microscopy, Yokly Leng, Collin N. Britten, Fatema Tarannum, Kayla Foley, Christopher Billings, Yingtao Liu, Keisha B. Walters

Chemical Engineering Faculty Publications and Presentations

Phosphorus-based stimuli-responsive hydrogels have potential in a wide range of applications due to their ionizable phosphorus groups, biocompatibility, and tunable swelling capacity utilizing hydrogel design parameters and external stimuli. In this study, poly(2-methacryloyloxyethyl phosphate) (PMOEP) hydrogels were synthesized via aqueous activators regenerated by electron transfer atomic transfer radical polymerization using ascorbic acid as the reducing agent. Swelling and deswelling behaviors of PMOEP hydrogels were examined in different salt solutions, pH conditions, and temperatures. The degree of swelling in salt solutions followed CaCl₂ < MgCl₂ < KCl < NaCl with a decrease in swelling rate at higher concentrations until reaching a saturation point. In water, the degree of swelling increased significantly around neutral pH and remained constant at basic pH values. The effects of polymerization conditions, including pH, temperature (30, 40, 50 °C), and MOEP concentration (40, 50, 60% v/v MOEP/H₂O), on the hydrogel swelling behavior in various salt solutions were also investigated. PMOEP hydrogels …

On Weak Solutions And The Navier-Stokes Equations, Aryan Prabhudesai

Mathematical Sciences Undergraduate Honors Theses

In this paper, I will discuss a partial differential equation that has solutions that are discontinuous. This example motivates the need for distribution theory, which will provide an interpretation of what it means for a discontinuous function to be a “solution” to a PDE. Then I will give a detailed foundation of distributions, including the definition of the derivative of a distribution. Then I will introduce and give background on the Navier-Stokes equations. Following that, I will explain the Millennium Problem concerning global regularity for the Navier-Stokes equations and share mathematical results regarding weak solutions. Finally, I will go over …

Localized Hermite Method Of Approximate Particular Solutions, Kwesi Acheampong

Dissertations

A localized Hermite method of approximate particular solutions (LHMAPS) is presented in this dissertation. This method is designed to improve the accuracy of the localized method of approximate particular solutions (LMAPS) for solving partial differential equations. LMAPS is a strong-form method that defines local radial basis function approximations to the solution values at a group of collocation points before applying the differential operator to this approximation function. Based on the LMAPS's local scheme, LHMAPS seeks Hermite-type local approximations based on both function values and derivatives. Numerical experiments validate the superior accuracy of the proposed method to the LMAPS by solving …

Elevating Commodity Polymers To Advanced Applications In Polymer Photonics And Polymer-Derived Porous Materials, Mark Robertson

Dissertations

Since the inception of synthetic polymers, polymer-derived materials have permeated into essentially all aspects of our daily lives. The most commonly thought of examples of polymer materials involve single-use, disposable products to increase shelf lives of perishable items, act as personal protective equipment, or provide some degree of convenience for the consumer. However, as we have furthered our understanding of polymer chemistry and polymer physics to develop increasingly sophisticated polymer systems, polymer materials have been employed in incredibly advanced applications. These include solid electrolytes for energy storage, matrices for aerospace grade carbon fiber-reinforced composites, membranes for liquid and gas separations, …

Eps Component Report Of Findings: Co-Curricular & Extra-Curricular Activities, Amy F. Johnson Phd, James E. Sloan, Sharon Gerrish

Co-Ex Curricular

Co- and extra- curricular activities are offered outside the curriculum, usually after school. The Maine School Financial Accounting Handbook defines co-curricular and extracurricular activities as activities and programs that add to the educational experience of students but are not related to educational activities and take place outside the traditional classroom. Co-curricular activities may be programs such as band, academic clubs, choir, and honor societies, and intramural sports. Extra-curricular activities are defined as interscholastic athletic programs.

Eps Component Review: Professional Development, Amy F. Johnson Phd, James E. Sloan, Sharon Gerrish

Professional Development

Professional Development is an Essential Programs and Services (EPS) component in the category of Specialized Services. The EPS Committee of the Maine State Board of Education established that “sustained professional development is key to helping staff acquire and maintain the new skills and knowledge necessary for continually improving curriculum, instruction and assessment practices” (SBOE, 1998). The EPS Committee also asserted that some professional development should be implemented at the district level and therefore be funded within the EPS model, while other programs may be more effective at the state or regional level and should be funded outside of the EPS …

Eps Component Report Of Findings: Instructional Technology, Amy F. Johnson Phd, James E. Sloan, Sharon Gerrish

Instructional Technology

When the Essential Programs and Services (EPS) funding model was being developed, the EPS of the State Board of Education held that “technology resources are key to equalizing access to worldwide learning resources for all Maine schools and students” to help students achieve the Learning Results (MSBOE, 1998). The committee stated that the EPS Model should cover the annual operating costs of personnel, training and support for teachers, and maintenance of devices and infrastructure, and that the purchase of hardware and software should be treated as capital investments and funded outside the EPS Model. The initial allocation was $175 per …

A Flood Of Consequences In Louisville, Kentucky: Using Hgis To Track Refugees Impacted By The 1937 Ohio River Flood, Trevor Harry

Masters Theses & Specialist Projects

The Ohio River flood of 1937 was the most devastating flood in the recorded history of the Ohio River Valley and is commonly referred to as the “Great Flood of 1937”. In January 1937, after nearly two months of continuous precipitation, over 60% of the city of Louisville, Kentucky, was flooded and at least 23,000 residents were displaced. The purpose of this research was to document, map, and compare the pre-flood residential locations, evacuation destinations, and post-flood residential locations of African American and White Louisville refugees from the 1937 Ohio River flood. Socioeconomic information from the manuscript versions of the …

Contaminant Transport Mechanisms And Source Tracking In Karst Groundwater Systems Under Agricultural Land Use, Shreya Pandey

Masters Theses & Specialist Projects

Karst areas in general face severe groundwater contamination problems that can degrade their water quality. In comparison to other landscapes, groundwater within karst regions is more susceptible to contamination. The situation gets worse when agriculture is practiced in these karst regions, because the nutrients and bacteria like nitrates and E. coli (Escherichia coli) are released into the groundwater systems which contaminate the water quality of those karst groundwater systems. This research aims to study the impacts of these contaminants, specifically nitrates and E. coli., by identifying the contaminant transport mechanisms and source tracking of these contaminants in the groundwater under …

Catalytic Hydrogenation Of Co2 In Water And Ionic Liquids Using Platinum On Carbon, Kristin Collins

Masters Theses & Specialist Projects

Platinum-on-carbon (Pt/C) is a commercially-available catalyst that has been used in the literature to benchmark the performance of catalysts produced using platinum/cobalt alloy nanoparticles. Initially, we intended to build upon this example by synthesizing shape-controlled platinum/cobalt alloy nanoparticles in ionic liquids and compare their ability to catalyze the hydrogenation of CO₂ to methanol against Pt/C as a benchmark, with the idea that ionic liquids may improve catalysis. However, we found that Pt/C was unable to catalyze the hydrogenation of CO₂ to methanol. In an attempt to track the source of this discrepancy, Pt/C was characterized using thermogravimetric analysis …

Polygenetic Cave Sedimentation And Speleogenesis In The Mccloud Limestone Of Northern California, Niles Lathrop

Masters Theses & Specialist Projects

Caves in the Permian-aged, McCloud Limestone of the Klamath Mountains of Northern California preserve a diverse range of clastic sediments that represent broad-scale variations in paleo-hydrologic conditions and transport mechanisms that hint at varied modes of speleogenesis through local landscape development. Caves in the McCloud Limestone exhibit a range of cave passage geometries and arrangements that suggests periods of both hypogene and epigene cave development through temporal and spatial scales. This study evaluates the variability in the distribution, mineralogy, and transport mechanisms of clastic-cave sediments in seven hydrologically-distinct caves in the McCloud Limestone to establish relationships between clastic-cave sedimentation and …

Comprehensive Climate Vulnerability Assessment Of A Regional Karst Landscape For Hazard Mitigation Planning, Kara Brunot

Masters Theses & Specialist Projects

Climate change is the global phenomena affecting all sectors of society by creating conditions more conducive for the occurrence of extreme weather events. It is projected that the intensity and frequency of events will increase. Flooding, in particular, is projected to increase in frequency due to more intense precipitation events. Karst landscapes are especially vulnerable to climate change impacts because of their unique hydrology and geology. Karst flooding is most likely to occur from prolonged or intense rain events, which climate change will likely make more feasible. Areas are disproportionately affected by climate change due to population demographics and environmental …

Perceptions And Visual Awareness Of Urban Karst Flooding To Inform Preparedness Planning And Management Actions, Grace Hermann

Masters Theses & Specialist Projects

Awareness and perception of flooding can heavily affect how an individual or community prepares for flooding. Flood awareness can be affected by factors like past flood experience and demographics. Flood experience and demographics can affect flood awareness differently based on factors including the types and cause of flooding. Flooding in karst landscapes can vary from other types of flooding and neither perception nor awareness of karst flooding has been directly studied before. This study explored both expert and non-expert flood awareness and perception and flood policies in a karst landscape through interviews with experts, surveys, and cognitive mapping activities. The …

Development And Application Of The Sinkhole Hazard Risk Index To Inform Karst Policy And Mitigation Planning, Meghan Puente

Masters Theses & Specialist Projects

Sinkholes are geologic hazards that occur in karst landscapes and can be highly destructive and costly. Sinkhole mitigation plans and development policies are nonexistent at the federal level within the United States and vary significantly at the state level. The lack of a unified standard for sinkhole mitigation planning is partly due to a lack of available data and resources needed to assess sinkhole risk. While there are established sinkhole assessments within the literature, they focus more on the detection and prediction of sinkholes rather than a holistic approach to risk assessment. The goal of this study is to create …

Application Of Agent-Based Simulation And Game Theory In Evaluating Implementation Of Whole Genome Sequencing In Treating Lung Cancer, Fateme Ghalenoei

Master's Theses

Cancer, particularly lung cancer, presents significant diagnostic and economic challenges globally. Timely diagnosis and cost management play pivotal roles in treatment success. A biomarker is any measurable molecule in blood, bodily fluids, or tissues, indicating the potential presence of an abnormal bodily process, condition, or disease. Biomarker testing is a laboratory test in oncology that is used in the selection of targeted cancer treatments and to help avoid ineffective treatments. Whole Genome Sequencing (WGS), is a biomarker test which while more comprehensive, comes at a higher cost. This study proposes an agent-based simulation model within a game-theoretic framework to examine …