Digital Commons Network^™

Synthesis And Characterization Of Nial-Hydride Heterometallics: Perturbing Electron Density Within Al–H–Ni Subunits, Aleida G. Gonzalez, Fernando Gonzalez, Edgar De Leon, Kaitlyn M. Birkhoff, Sam Yruegas, Haoyuan Chen, Manar Shoshani

School of Integrative Biological & Chemical Sciences Faculty Publications

Heterometallic hydride complexes are of growing interest due to their potential to contribute to highly active insertion-based catalysis; however, methods to modulate electron density within this class of molecules are underexplored. Addition of ancillary ligands to heterotrimetallic NiAl2H2 species (1) results in the formation of heterobimetallic NiAl-hydride complexes with varying phosphine donors (2-(L)2). Incorporation of sigma donating ancillary ligands of increasing strength led to contractions of the Ni–Al distances correlated to a strengthening of a back donation interaction to the Al–H sigma antibonding orbital, most prominently present in 2-(PMe3)2. Demethylation of the aryl ether from 2-(PMe3)2 provides access to a …

July 2024 Berkeley Pit Migratory Waterfowl Protection Monthly Report, Mark Thompson, Loren Burmeister

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Clinical And Genomic-Based Decision Support System To Define The Optimal Timing Of Allogeneic Hematopoietic Stem-Cell Transplantation In Patients With Myelodysplastic Syndromes, Cristina Astrid Tentori, Caterina Gregorio, Marie Robin, Nico Gagelmann, Carmelo Gurnari, Somedeb Ball, Juan Carlos Caballero Berrocal, Luca Lanino, Saverio D'Amico, Marta Spreafico, Giulia Maggioni, Erica Travaglino, Elisabetta Sauta, Manja Meggendorfer, Lin-Pierre Zhao, Alessia Campagna, Victor Savevski, Armando Santoro, Najla Al Ali, David Sallman, Francesc Sole, Guillermo Garcia-Manero, Ulrich Germing, Nicolaus Kroger, Shahram Kordasti, Valeria Santini, Guillermo Sanz, Wolfgang Kern, Uwe Platzbecker, Maria Diez-Campelo, Jaroslaw P Maciejewski, Lionel Ades, Pierre Fenaux, Torsten Haferlach, Amer M Zeidan, Gastone Castellani, Rami Komrokji, Francesca Ieva, Matteo Giovanni Della Porta, Genomed4all And Synthema Consortiums

Faculty, Staff and Student Publications

Purpose: Allogeneic hematopoietic stem-cell transplantation (HSCT) is the only potentially curative treatment for patients with myelodysplastic syndromes (MDS). Several issues must be considered when evaluating the benefits and risks of HSCT for patients with MDS, with the timing of transplantation being a crucial question. Here, we aimed to develop and validate a decision support system to define the optimal timing of HSCT for patients with MDS on the basis of clinical and genomic information as provided by the Molecular International Prognostic Scoring System (IPSS-M).

Patients and methods: We studied a retrospective population of 7,118 patients, stratified into training and validation …

The Sufficiency Of Disclosure Of Ai Inventions, Mateo Aboy, Aparajita Lath, Timo Minssen, Kathleen Liddell

Articles

• The complex and data-driven nature of artificial intelligence (AI) raises questions for the sufficient disclosure of patent applications in this field. What are the European patent disclosure requirements for AI inventions?

• One challenge is that, prior to training, AI systems can be considered generic models. But after training, they transform into specialized AI systems to solve a particular problem. This transformation requires training data, making it an integral part of the AI system’s definition. But to what extent is the disclosure of the training data or training process necessary for patent disclosure?

• The Boards of Appeal of the European Patent …

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An Investigation Of Mortality Associated With Comorbid Pneumonia And Thrombocytopenia In A Rural Southwest Missouri Hospital System, Tabitha Ranson, Hannah Rourick, Rajbir Sooch, Nicole R. Ford, Nova Beyersdorfer, Kerry Johnson, John Paulson

Faculty and Staff Publications

Background: Pneumonia places a significant burden on individuals and society, contributing to a substantial number of hospital admissions, emergency department visits, deaths, and healthcare costs each year. Comorbidities can greatly increase the risk of poor outcomes when associated with pneumonia. One comorbidity that has yet to be thoroughly researched is thrombocytopenia, which is known to play an important role in activating the immune response to infections. A decrease in platelet count may limit the immune response and consequently increase mortality in patients with pneumonia. The purpose of this study was to investigate whether comorbid thrombocytopenia and pneumonia are associated with …

Spatial Optimism And Cross-Over Effects In The Perceptions Of Interconnected Wildfire, Flood, And Mudslide Hazards, Douglas Houston, Omar Pérez Figueroa, Ariane Jong-Levinger, Brett F. Sanders

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Communities near the wildland urban interface (WUI) are exposed to a mix of three interconnected hazards (wildfire, flood, and mudslide), and understanding multi-hazard perceptions is critically important for emergency preparation and hazard mitigation—particularly given the WUI’s rapid expansion and intensifying environmental hazards. Based on a survey of residents living near recent burn scars in Southern California, we document cross-over effects in hazard perceptions, where resident experience with one hazard was associated with greater hazard rankings for other hazards. Additionally, for all three hazards analyzed we document perceptions of increasing hazard levels with increasing spatial scales (home, near-home, neighborhood, and community), …

Influence Of Academic Abstract Variables On Geospatial Skills Of Undergraduate Students: An Exploratory Study, Kanika Verma

The Geographical Bulletin

Spatial thinking and learning are essential components of geography education . The National Research Council’s 2006 report “Learning to Think Spatially” emphasized that people vary with respect to performance on spatial tasks . This pilot study at a large Texas university investigated geospatial thinking variances among undergraduate students based on academic experience of students . T his exploratory study uses the Geospatial T hinking Survey (GTS), based on the Spatial T hinking Ability Test (STAT) endorsed by Association of American Geographers (2006) and published by Lee and Bednarz (2012), to assess the geospatial thinking differences of undergraduate students . The …

Member-Reported Benefits Of Three Alabama Educator-Focused Professional Organizations, Meredith L. C. Sides

Journal of Educational Research and Practice

Professional organizations can play an important role in the lives and work of educators. The purpose of this qualitative study was to explore Alabama educators’ experiences with membership in statewide professional organizations and to determine what benefits, if any, members feel their organizations provide them. Four main benefits that respondents identified were community, broadening of knowledge and practice, leadership opportunities, and personal growth.

Youth Dignity Takings: How Book And Trans Bans Take Youth Property And Dignity, Sarah M. Camiscoli, Paige Duggins-Clay, Maryam Salmanova, Ibtihal Chamakh

Loyola Interdisciplinary Journal of Public Interest Law

This article practices Participatory Law Scholarship and Movement Law to engage Marginalized and Mobilized Youth in legal scholarship and to elevate their resistance against book bans and trans bans. Together, we—a legal scholar-practitioner, frontline movement lawyer, Youth community legal worker, and law student-activist—make the positive claim that book bans and trans bans constitute a dignity taking—a state action that takes property from a marginalized group and dehumanizes and infantilizes that group in the process. Further, we make the normative claim that legal advocates committed to repairing the deprivations of these bans and bills must attend to both the material loss …

Transforming Computer Science Pedagogy: An Exploration Of Self-Recorded Videos (Srv) As A Teaching And Evaluation Tool, Hussam Ghunaim

Computer Science Faculty Publications

This study aims to introduce Self-Recorded Videos (SRV) as a novel method to help improve students’ performance in coding assignments in computer science courses. To our best knowledge, this is the first time the SRV method is applied in the context of computer science classes. The study was conducted with a sample size of 41 students who were registered in the online CSCI 331 Operating Systems course at Fort Hays State University. These students were given specific instructions to create Self-Recorded Videos SRVs for every coding assignment they were tasked with. This approach was designed to encourage students to engage …

An Analysis Of Trends In The Use Of Animal And Non-Animal Methods In Biomedical Research And Toxicology Publications, Katy Taylor, Stephani Modi, Jarrod Bailey

Non-Animal Methods and 3Rs

There have been relatively few attempts to quantitatively assess if, and in which areas, the use of non-animal methods (NAMs) is increasing in biomedical research and importantly, how this compares to the use of live animals. We found that proportionately the reliance on animals in these research areas is decreasing, which will be encouraging to those that support the replacement of animal experiments.

Living Collections: Biodiversity Cultivated At Public Gardens Has The Power To Connect Ecological Questions And Evolutionary Context, Jean H. Burns, Katharine L. Stuble, Juliana S. Medeiros

Faculty Scholarship

Combining ecological questions with evolutionary context generates novel insight into both ecology and evolution. However, our ability to draw broad inferences can be limited by the taxonomic diversity present within and across species at a site. Public gardens (including botanical gardens and arboreta) may focus solely on aesthetics in developing their gardens, but some public gardens include scientific inquiry and conservation at the core of their missions (Hohn, 2022). These scientifically oriented public gardens follow community standards of excellence (Hohn, 2022) to provide unique access to curated plant collections specifically designed to gather high levels of biodiversity, both among and …

Representation Dimensions Of Algebraic Tori And Symmetric Ranks Of G-Lattices, Jason Bailey Heath

Theses and Dissertations

Algebraic tori over a field k are special examples of affine group schemes over k, such as the multiplicative group of the field or the unit circle. Any algebraic torus can be embedded into the group of invertible n x n matrices with entries in k for some n, and the smallest such n is called the representation dimension of that torus. Representation dimensions of algebraic tori can be studied via symmetric ranks of G-lattices. A G-lattice L is a group isomorphic to the additive group Zⁿ for some n, along with an action …

Multiple Guidance Mechanisms Control Axon Growth To Generate Precise T-Shaped Bifurcation During Dorsal Funiculus Development In The Spinal Cord, Bridget M. Curran, Kelsey R. Nickerson, Andrea R. Yung, Lisa V. Goodrich, Alexander Jaworski, Marc Tessier-Lavigne, Le Ma

Farber Institute for Neuroscience Faculty Papers

The dorsal funiculus in the spinal cord relays somatosensory information to the brain. It is made of T-shaped bifurcation of dorsal root ganglion (DRG) sensory axons. Our previous study has shown that Slit signaling is required for proper guidance during bifurcation, but loss of Slit does not affect all DRG axons. Here, we examined the role of the extracellular molecule Netrin-1 (Ntn1). Using wholemount staining with tissue clearing, we showed that mice lacking Ntn1 had axons escaping from the dorsal funiculus at the time of bifurcation. Genetic labeling confirmed that these misprojecting axons come from DRG neurons. Single axon analysis …

Macro–Micro-Coupled Simulations Of Bead–Spring Breaking-Reforming Networks, Andrei Medved

Theses and Dissertations

In this work we investigate the dynamic behavior of bead-spring polymer solutions in viscoelastic fluids, which are essential in industries like materials science, biotechnology, and pharmaceuticals. The study leverages GPU-accelerated simulations and detailed modeling of polymer chain dynamics at the mesoscale, which enables efficient analysis of intricate fluid behaviors and the microscale dynamics of polymer chains. Additionally, the research examines the breaking-reforming dynamics of polymer chains, crucial for understanding phenomena such as shear thinning and thickening. The findings have broad applications, from improving inkjet printing and 3D printing technologies to developing new drug delivery systems and biocompatible materials. This work …

Bayesian Methods In Analyzing The Diagnostic Accuracy\\ For Ordinal Ratings, Yun Yang

Theses and Dissertations

This dissertation focuses on ordinal classification ratings, which are commonly used in medical practice to assess the severity of a disease or condition. For example, a group of radiologists rate a set of mammograms and assign BI-RADS (Breast Imaging Reporting Data System) score for each mammogram. A Bayesian probit hierarchical model is first proposed to analyze this type of data. It links the ordinal ratings with both rater diagnostic skills and patient latent disease severity. Each rater diagnostic skills are quantified with two parameters, diagnostic bias and diagnostic magnifier. Patient latent disease severity is assumed to follow a different normal …

Object Classification, Detection And Tracking In Challenging Underwater Environment, Md Modasshir

Theses and Dissertations

The main contributions of this thesis is the applicability and architectural designs of deep learning algorithms in underwater imagery. In recent times, deep learning techniques for object classification and detection have achieved exceptional levels of accuracy that surpass human capabilities. However, the effectiveness of these techniques in underwater environments has not been thoroughly researched. This thesis delves into various research areas related to underwater environments, such as object classification, detection, semantic segmentation, pose regression, and semi-supervised retraining of detection models.

The first part of the thesis studies image classification and detection. Image classification is a fundamental process that involves assigning …

Examining The Overall Impact Of Computer-Based Mathematics Instruction On Math Achievement In An Alternative High School, Jacqueline Levon Gilyard

Theses and Dissertations

Over the past decade, the United States has witnessed a remarkable surge in computer-based instruction, revolutionizing the way students learn and educators teach. This action research study aimed to investigate the overall impact of computer-based instruction on mathematics achievement in the alternative high school setting. The research design incorporated both quantitative and qualitative methods to gather comprehensive data for twenty high school students enrolled in an alternative high school setting. The quantitative data analysis involved examining pre-and post-test scores, graduation data, and final course grades to assess the effect of computer-based instruction on mathematics achievement. All of the students showed …

Plotting For Change: Utilizing Computer-Based Scaffolding Through Desmos To Influence High School Students’ Performance And Attitudes Toward Mathematics, Jennifer Underwood Farmer

Theses and Dissertations

The purpose of this action research was to understand the impact of computer-based instructional scaffolding in Desmos on Math 3 high school students’ performance and attitudes toward mathematics. The demand for societal mathematics literacy has increased significantly over the last decade and continues to grow. To achieve this literacy, students must reason, augment, communicate, model, and problem-solve with technology applications; development of these skills requires engagement and support through technology-rich learning opportunities.

Currently, Math 3 students are not performing at the proficient level on state exams and are displaying negative attitudes towards mathematics. Student attitudes and performance in technology enhanced …

B-Spline Impulse Response Functions For Transient Ssi Analysis Of Pile Foundations, Kingsley C. Ozegbe

Theses and Dissertations

The advent and consequential advancements in geotechnical earthquake engineering has made soil-structural analysis (SSI) an important component in the analysis and design of earthquake resistant structures. The filtering effects of pile foundations which reduces the seismic demand on pile-supported superstructure when they are subjected to seismic waves have been investigated and confirmed by several researchers in the last 40 years. To this end, several methods of analyzing the effects of SSI have been developed over the years. From the simplified Winkler model to the more robust finite element method (FEM) and boundary element method (BEM), researchers and structural engineers alike …

Developing A Hierarchical Digital Twin Framework For Dc Microgrid Implementation, Khari Sado

Theses and Dissertations

This research introduces a hierarchical digital twin framework for DC microgrids implementation, particularly those utilized in naval power systems. Unlike traditional digital twins, this hierarchical digital twin structure offers a layered perspective. Hierarchical digital twin design promotes computational efficiency by distributing computational burden across a layered configuration that integrates lower-level digital twin blocks with a system digital twin. The layered approach breaks down complex systems into smaller manageable units that can be examined individually and collectively. Central to this strategy is the adoption of a multi-domain and multi-functional technique through the integration of the digital image framework. This allows the …

Signatures Of Fluid-Rock Interactions In Shallow Parts Of The San Andreas And San Gabriel Faults, Southern California, James P. Evans, Kaitlyn Crouch, Caroline Studnicky, Sharon Bone, Nicholas Edwards, Samuel M. Webb

Geosciences Faculty Publications

We examine deformed crystalline bedrock in the upper parts of the active San Andreas and ancient San Gabriel Faults, southern California, to 1) determine the nature and origin of micro-scale composition and geochemistry of fault-related rocks, 2) constrain the extent of fluid-rock interactions, and 3) determine the interactions between alteration, mineralization, and deformation. We used drill cores from a 470 m long inclined borehole through the steep-dipping San Gabriel Fault and from seven inclined northeast-plunging boreholes across the San Andreas Fault zone to 150 m deep to show that narrow fault cores 10 cm to 5 m wide lie within …

Electron Rich Cobaltocenium Derivatives As Tunable Mechanophores For Mechanochemistry, Luis Daniel Ramos

Theses and Dissertations

In this dissertation, metallocene-containing polymers are investigated and probed for tunability in mechanochemistry. These metallocene moieties are experimentally and computationally characterized.

In chapter 1, relevant background and recent developments of metallocene-containing polymers are discussed. Additionally, the field of mechanochemistry is briefly introduced including applications and future directions within the field.

In chapter 2, design and synthesis of these metallocene-containing polyelectrolytes via ring opening metathesis polymerization (ROMP) are outlined. These polymers then undergo mechanophore activation via ultrasonication and relevant analysis and characterization of polymers both before and after ultrasonication are detailed. These polymers are comprised of differing electron donating substituents on …

08.19.2024 Orsp Connect, Liz Williamson

ORED Newsletter

Lei Cao NSF award

FDP Meeting Summaries Available

August LINC Lunch

Collaboration Opportunities

The Impact Of Delaying Early School Tracking On Fertility And Marriage Outcomes, Serena Canaan

Upjohn Institute Working Papers

This paper studies how the type of education pursued at an early age affects family formation. I focus on a French reform that delayed the age of which students were tracked into either general or vocational education from age 11 to age 13. For the most part, tracking was replaced with grouping students into classrooms based on ability, but within a common general education curriculum. Using a regression discontinuity design, I show that the reform increased the likelihood of attaining a technical rather than a vocational degree, especially for individuals from low socioeconomic backgrounds. This indicates that the reform led …

Deconvolving Provenance Signatures Of Pliocene-Pleistocene Coastal Loess Deposits Along The Atlantic Margin Of Argentina, Will Robert Quanrud

Theses and Dissertations

Dust derived from southern South America provides critical nutrients for autotropic marine biota in the South Atlantic Ocean, such that fluxes of wind-blown sediment may ultimately affect the concentration of atmospheric CO2. Expansive sand, silt, and loess deposits are exposed in Central Argentina, recording millions of years of eolian processes; however, the provenance and transport pathways of this dust remains unclear. Coastal loess deposits ranging in age from Pliocene to upper Pleistocene are present along the Atlantic margin of Argentina and provide information on sediment transport pathways for the last 4 million years. Nine samples of loess were collected and …

Generalizations Of The Graham-Pollak Tree Theorem, Gabrielle Anne Tauscheck

Theses and Dissertations

Graham and Pollak showed in 1971 that the determinant of a tree’s distance matrix depends only on its number of vertices, and, in particular, it is always nonzero. This dissertation will generalize their result via two different directions: Steiner distance k-matrices and distance critical graphs. The Steiner distance of a collection of k vertices in a graph is the fewest number of edges in any connected subgraph containing those vertices; for k = 2, this reduces to the ordinary definition of graphical distance. Here, we show that the hyperdeterminant of the Steiner distance k-matrix is always zero if …

Metal-Organic Frameworks For Global Environmental Challenges, Kyoungchul Park

Theses and Dissertations

Over the past few decades, there has been a demand for improving nuclear waste administration due to a significant increase in the utilization of nuclear energy. The driving force for proper nuclear waste disposal is evident when considering past nuclear catastrophes—such as Chernobyl and Fukushima—where radionuclide contamination of large bodies of water sparked public concern. In order to manage such radioactive species, the emerging areas of radionuclide sequestration, storage, separation, and sensing must be addressed in the upcoming years. This dissertation presents a potential candidate for addressing these challenges, called metal-organic frameworks (MOFs). Due to their porosity, high surface area, …

Modeling, Analysis, Approximation, And Application Of Viscoelastic Structures And Anomalous Transport, Yiqun Li

Theses and Dissertations

(Variable-order) fractional partial differential equations are emerging as a competitive means to integer-order PDEs in characterizing the memory and hereditary properties of physical processes, e.g., anomalously diffusive transport, viscoelastic mechanics and financial mathematics, and thus have attracted widespread attention. In particular, optimal control problems governed by fractional partial differential equations are attracting increasing attentions since they are shown to provide competitive descriptions of challenging physical phenomena. Nevertheless, variable-order fractional models exhibit salient features compared with their constant-order analogues and introduce mathematical difficulties that are not typical encountered in the context of integer-order and constant-order fractional partial differential equations.

This dissertation …

Exploring Human Capital Development: Perspectives Of Young Adults (Aged 18-25) In Lagos, Nigeria, Omobola Omotimirin

Walden Dissertations and Doctoral Studies

Under-utilization of youth human capital and youth delusion, has the attendant effect of increased crime, insecurity, deplorable infrastructure, loss of foreign investment, revenue loss, etc. The large population of young adults (age 18-25) in Lagos State, Nigeria, is a source of human capital development. There is little to no literature on the young adults’ (age 18-25) perspectives on their human capital development in Lagos State. The purpose of this study was to understand the perspectives of young adults (age 18-25) on their human capital development needs. Research questions focused on understanding young adults’ perception on human capital development; how youth …