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Towards Age-Inclusive Human Computer Interaction: A Study Of Text Message Adoption By Seniors, Sam Takavarasha, Varaidzo Mapepa Aug 2025

Towards Age-Inclusive Human Computer Interaction: A Study Of Text Message Adoption By Seniors, Sam Takavarasha, Varaidzo Mapepa

African Conference on Information Systems and Technology

Since mobile phones are increasingly becoming livelihoods-enablers to people in developing economies, inclusive interaction design are critical. This research on the age inclusivity of feature phones was motivated by some observation that elderly users had challenges with adoption of text messaging. We, therefore, hypothesized that elderly people had challenges with texting ‘cash’, ‘cheque’ or ‘visa’ on a feature phone. The paper investigates if the required agility and interface ergonomics were age discriminatory inhibitors of the adoption of text messaging given the diminishing dexterity and cognitive skills of seniors. Using Sen’s (1999) ‘heterogeneity of capabilities’ theory and Davis et al (1989)’s …

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The Effect Of Blended Learning Technique On Fourth Grade Students’ Achievement And Their Ability To Solve Algebraic Problems In Mathematics, Mohammad Al-Shugayrat Aug 2025

The Effect Of Blended Learning Technique On Fourth Grade Students’ Achievement And Their Ability To Solve Algebraic Problems In Mathematics, Mohammad Al-Shugayrat

Jordan Journal of Applied Science-Humanities Series

This study aimed to investigate the effect of blended learning on fourth-grade students’ achievement and their ability to solve algebraic problems in mathematics at the Southern Badia Directorate of Education. The sample consisted of 60 male and female fourth-grade students from Grain Basic School, who were divided into two groups: the experimental group and the control group. The study sought to determine whether there are statistically significant differences in the students’ achievement and their ability to solve algebraic problems in mathematics. To answer the research questions, the researcher developed an achievement test and a test assessing the ability to solve …

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Levels Of Academic Procrastination Among Students Of Princess Rahma University College At Al-Balqa Applied University And Their Variation By Place Of Residence, Omar Al-Khamaiseh Aug 2025

Levels Of Academic Procrastination Among Students Of Princess Rahma University College At Al-Balqa Applied University And Their Variation By Place Of Residence, Omar Al-Khamaiseh

Jordan Journal of Applied Science-Humanities Series

This study aimed to identify the levels of academic procrastination and the differences based on place of residence (village, city, refugee camp) among the students of Princess Rahma University College at Al-Balqa Applied University. The study sample consisted of 140 male and female students, who were selected using stratified sampling from the study population. The academic procrastination scale, which consists of 15 items, was used to measure the extent of a student’s postponement of academic duties and assignments. The results of the study indicated that the level of academic procrastination among the students of Princess Rahma University College at Al-Balqa …

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Creepy, Invasive, And Exploitative Algorithms: A Cpm Analysis Of Users' Privacy Breakdowns And Recalibration Practices With Social Media Algorithms, Matthew J. A. Craig, Jeffrey T. Child Aug 2025

Creepy, Invasive, And Exploitative Algorithms: A Cpm Analysis Of Users' Privacy Breakdowns And Recalibration Practices With Social Media Algorithms, Matthew J. A. Craig, Jeffrey T. Child

Human-Machine Communication

Social media content filtering algorithms can both provide desired personalized content and ads for users. However, sometimes these recommendations can resemble individual private information. How might users navigate these experiences to best manage their private information? The present exploratory study utilizes the rules- and systems-based framework of communication privacy management (CPM) theory to explore social media users’ experiences of privacy breakdowns with social media algorithms and investigates what users do in response to said breakdowns. These responses were refined using content analysis and divided into different categories of privacy breakdowns and recalibration strategies. Implications for future research surrounding human-machine communication …

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The Hai-Io Model: A Framework For Understanding The Human-Ai Communication Process, Rae Francis Quilantang Aug 2025

The Hai-Io Model: A Framework For Understanding The Human-Ai Communication Process, Rae Francis Quilantang

Human-Machine Communication

The increasing integration of artificial intelligence (AI) into daily life calls for new theoretical frameworks that capture human-AI interaction’s dynamic, feedback-driven nature. Traditional models treat AI as a passive medium, overlooking its adaptive capabilities. This paper proposes the Human-AI Interaction Outcomes (HAI-IO) model, an interdisciplinary framework synthesizing human-machine communication, social exchange theory, dialogue systems, and computational feedback models like cybernetics and reinforcement learning. The HAI-IO model frames interaction as iterative and bidirectional—AI adapts through predictive processing while users adjust based on AI feedback. This mutual adaptation shapes trust, engagement, and system optimization. The model informs AI system design, user education, …

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Casa Renovations: Examining Social Responses To An Anthropomorphic Media Representative That Is Separate From The Core Technology Being Represented, Rabindra Ratan, Dayeoun Jang, Taenyun Kim, Kelsey Earle, Gabriel E. Hales, Yiming Skylar Lei, Chaeyun Lim, Andrew Gambino Aug 2025

Casa Renovations: Examining Social Responses To An Anthropomorphic Media Representative That Is Separate From The Core Technology Being Represented, Rabindra Ratan, Dayeoun Jang, Taenyun Kim, Kelsey Earle, Gabriel E. Hales, Yiming Skylar Lei, Chaeyun Lim, Andrew Gambino

Human-Machine Communication

To extend our understanding of CASA and account for changes in technological complexity and configuration, this research asks: Do increasing levels of social cues in a media representative that is separate from the core technology it represents lead to increased perceived anthropomorphism of the core technology? And does such perceived anthropomorphism predict positive treatment of the core technology? We conducted two complementary studies observing e-scooter use and treatment, an online experiment focused on responses to video stimuli and a field experiment focused on actual user behavior. Findings suggest that, indeed, social cues in a media representative (i.e., an e-scooter rental …

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Robot Prosecutors And The Future Of Criminal Justice In Indonesia: Innovation, Ethics, And Legal Implications, Kurnia Dewi Anggraeny, Zico Junius Fernando, Kasmanto Rinaldi Aug 2025

Robot Prosecutors And The Future Of Criminal Justice In Indonesia: Innovation, Ethics, And Legal Implications, Kurnia Dewi Anggraeny, Zico Junius Fernando, Kasmanto Rinaldi

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

Robot prosecutors represent the integration of robotic technology and artificial intelligence (AI) into the traditional role of a prosecutor, reflecting the global trend towards automation and the application of technology within the legal system. This concept is no longer merely a theoretical; it has begun to materialize in certain jurisdictions. For instance, China has emerged as a pioneer in this field by successfully developing an innovative AI program capable of not only of identifying crimes through detailed data analysis but also of filing appropriate lawsuits. This progress underscores the immense potential of this technology to enhance efficiency and accuracy in …

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Galvanizing Community, Support, Well-Being, And Self-Efficacy: Supporting Doctoral Candidates Throughout The Dissertation Writing Process, Njeri M. Pringle, Jamie L. Workman Aug 2025

Galvanizing Community, Support, Well-Being, And Self-Efficacy: Supporting Doctoral Candidates Throughout The Dissertation Writing Process, Njeri M. Pringle, Jamie L. Workman

Journal of Graduate Education Research

Recent data published by the Council of Graduate Schools indicates approximately 40% of students who begin doctoral coursework do not complete their degree. This asserts the need for graduate schools to examine ways in which they can support their doctoral student population, particularly through the dissertation writing process. The purpose of this autoethnographic study was to explore two methods of dissertation writing support: a dissertation writing group sponsored by a graduate school and independent dissertation coaching services. The article highlights key findings from each support system and provides implications for dissertation writing group facilitators, dissertation coaches, and graduate schools.

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The Emergence Of Ai Chatbots In Education, Trek Martin Aug 2025

The Emergence Of Ai Chatbots In Education, Trek Martin

Journal of Graduate Education Research

The recent advent of popular AI applications in educational contexts has sparked renewed interest in the question of AI and guided learning platforms as teaching tools. What are the possibilities for learning? In the attempt to answer that question, limitations of the field must be brought to full attention, as well an understanding of whether or not those limitations will continue into the immediate future; this research examines the technical evolution of artificial intelligence in education, from early symbolic reasoning systems to modern machine-learning-based chatbots. It then examines that evolution in terms of the key challenges it faced throughout, and …

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“We Are Swans:” An Ecological Analysis Of U.S. International Students’ Experiences Of Higher Education Satisfaction, Eunsong Park, Corey S. Shdaimah, Yao Wang Aug 2025

“We Are Swans:” An Ecological Analysis Of U.S. International Students’ Experiences Of Higher Education Satisfaction, Eunsong Park, Corey S. Shdaimah, Yao Wang

Journal of Graduate Education Research

International students make important contributions to the US academic landscape and broader society; however, their numbers continue to decline in the face of an unwelcoming and unsupportive environment compared to their counterparts worldwide. This manuscript presents findings from a student satisfaction survey (n = 423) that included both multiple-choice and open-ended questions. We used the ecological model and the Spanning Systems Model as a framework, looking at how individual, community, institutional, and larger societal factors impacted the experiences of international students in the US. For quantitative analysis, hierarchical multiple linear regressions were conducted to examine factors associated with student satisfaction. …

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Hurricane Katrina Archive: Faculty Publications Bibliography 2015-2019, Lsu Health Sciences Center - New Orleans Libraries, Sharon Duffy, Matthew Folse Aug 2025

Hurricane Katrina Archive: Faculty Publications Bibliography 2015-2019, Lsu Health Sciences Center - New Orleans Libraries, Sharon Duffy, Matthew Folse

LSUHSC Hurricane Katrina Archive: Bibliographies

This bibliography includes 19 articles about Hurricane Katrina written by authors affiliated with LSU Health – New Orleans between January 2015 and December 2019.

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Hurricane Katrina Archive: Faculty Publications Bibliography 2020-2025, Lsu Health Sciences Center - New Orleans Libraries, Sharon Duffy, Matthew Folse Aug 2025

Hurricane Katrina Archive: Faculty Publications Bibliography 2020-2025, Lsu Health Sciences Center - New Orleans Libraries, Sharon Duffy, Matthew Folse

LSUHSC Hurricane Katrina Archive: Bibliographies

This bibliography includes 10 articles about Hurricane Katrina written by authors affiliated with LSU Health – New Orleans between January 2020 and August 2025.

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Hurricane Katrina Archive: E-Books And E-Journals A To Z Bibliography 2020-2025, Lsu Health Sciences Center - New Orleans Libraries, Elizabeth H. Holt Aug 2025

Hurricane Katrina Archive: E-Books And E-Journals A To Z Bibliography 2020-2025, Lsu Health Sciences Center - New Orleans Libraries, Elizabeth H. Holt

LSUHSC Hurricane Katrina Archive: Bibliographies

This bibliography includes 43 electronic books and edited collections created on the topic of Hurricane Katrina by authors and others affiliated with LSU Health Sciences Center - New Orleans between September 2005 and August 2025.

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Reconstruction Of Water Storage Variability In The Aral Sea Region, Nikita Murzintcev, Sahibjamal Nietullaeva, Timur Berdimbetov, Buddhi Pushpawela, Asiya Tureniyazova, Sherly Shelton, Bakbergen Aytmuratov, Khusen Gafforov, Kanat Parakhatov, Alimjan Erdashov, Abdul-Aziz Makhamatdinov, Timur Allamuratov Aug 2025

Reconstruction Of Water Storage Variability In The Aral Sea Region, Nikita Murzintcev, Sahibjamal Nietullaeva, Timur Berdimbetov, Buddhi Pushpawela, Asiya Tureniyazova, Sherly Shelton, Bakbergen Aytmuratov, Khusen Gafforov, Kanat Parakhatov, Alimjan Erdashov, Abdul-Aziz Makhamatdinov, Timur Allamuratov

Plants, Soils and Climate Student Research

The Gravity Recovery and Climate Experiment (GRACE) mission, operational from 2002 to 2017, provided critical measurements of Earth's gravity field anomalies which have been extensively used to study groundwater and terrestrial water storage (TWS) dynamics. In this research, we utilize GRACE data to identify, model, and analyze potential climate parameters contributing to the reconstruction of TWS variability in the Aral Sea Basin region (ASB). We assess the impact of climate change and anthropogenic nature management on TWS change using a quantitative method. Our analysis reveals a significant decline in the TWS at a rate of 0.44 cm year-1 during …

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Empowering Youth Tackle Football Athletes: A Content Analysis Of Nonlinear Pedagogy’S Influence On Autonomy And Practical Applications In Youth Tackle Football, Benjamin Jay Andelman Aug 2025

Empowering Youth Tackle Football Athletes: A Content Analysis Of Nonlinear Pedagogy’S Influence On Autonomy And Practical Applications In Youth Tackle Football, Benjamin Jay Andelman

Masters Theses

Youth tackle football offers an environment that promotes both positive mental and physical benefits for young athletes. Despite the positive benefits associated with sports, participation is on the decline. The content analysis found connections between the prevailing prescriptive coaching methods in youth tackle football and the adverse mental effects on young athletes. This study, utilizing a qualitative content analysis of existing academic literature, proposes a practical application of Nonlinear Pedagogical principles in the youth tackle football practice context to develop a coaching model that promotes athlete autonomy, thereby increasing positive mental benefits for the youth athlete. Leveraging Ecological Dynamics, Constraints-Led …

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Understanding The Ontological Argument Through Love: The Paradox Between Faith And Reason, Bill Goodson Aug 2025

Understanding The Ontological Argument Through Love: The Paradox Between Faith And Reason, Bill Goodson

Masters Theses

This thesis argues that while the ontological argument as presented by Saint Anselm of Canterbury offers a formal logical explanation for the existence of God, love is presented as the bridge that enables the skeptic and the believer to engage the argument from a relational and experiential perspective in joining faith and reason through God’s divine love. The paradox found therein is that love, being kind, generous, and caring, initially appears to be too soft for the hard truth and sheer facts of reason. The calling of the theologian is to expose the good news of his faith, and his …

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Hurricane Katrina Archive: Libraries Catalog Bibliography, Lsu Health Sciences Center - New Orleans Libraries, Elizabeth H. Holt Aug 2025

Hurricane Katrina Archive: Libraries Catalog Bibliography, Lsu Health Sciences Center - New Orleans Libraries, Elizabeth H. Holt

LSUHSC Hurricane Katrina Archive: Bibliographies

This bibliography includes 15 books, videos, and edited collections created on the topic of Hurricane Katrina by authors and others affiliated with LSU Health Sciences Center - New Orleans between September 2005 and August 2025.

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Understanding User Needs In Health Crisis Risk Monitoring Information System Development: A Lesson From Tasikmalaya District, Indonesia, Arief Tarmansyah Iman, Hari Kusnanto, Ariani Arista Putri Pertiwi Aug 2025

Understanding User Needs In Health Crisis Risk Monitoring Information System Development: A Lesson From Tasikmalaya District, Indonesia, Arief Tarmansyah Iman, Hari Kusnanto, Ariani Arista Putri Pertiwi

Kesmas

A health crisis risk monitoring information system needs to be developed, especially during the pre-disaster phase; therefore, understanding the needs of prospective users is crucial. This study aimed to investigate the needs of potential users regarding the development of this system. This study employed a qualitative, exploratory approach to gather user needs from stakeholders through interviews (n = 7) and one focus group discussion (n = 12). The data were audio-recorded, transcribed verbatim, and then thematically analyzed using qualitative content analysis. The need for information was related to disaster preparedness and its preferred format. The system should be targeted, multiplatform, …

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Impact Of Temperature On Larval Mortality And Performance Of The Acorn Barnacle Chthamalus Fissus In San Diego, Ca, Alberto Rivera Aug 2025

Impact Of Temperature On Larval Mortality And Performance Of The Acorn Barnacle Chthamalus Fissus In San Diego, Ca, Alberto Rivera

Theses

Rising ocean temperatures and increasingly frequent marine heatwaves threaten the physiological performance and survival of marine larvae. This study quantifies the thermal tolerance, respiration, and swimming behavior of Chthamalus fissus cyprid larvae to establish a baseline for understanding their vulnerability under future climate scenarios. Larvae were collected from the Scripps Pier in La Jolla, CA and exposed to a range of temperatures (12–50°C, dependent on the experiment) to assess oxygen consumption, mortality, and swimming speeds. Oxygen consumption rates increased significantly with temperature, peaking at 30°C, with cyprids exposed to temperatures above 26°C showing significantly higher respiration rates than those below …

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A Partial Resolution Of Hedden’S Conjecture On Satellite Homomorphisms, Randall Johanningsmeier , '24, Hillary Kim , '25, Allison N. Miller Aug 2025

A Partial Resolution Of Hedden’S Conjecture On Satellite Homomorphisms, Randall Johanningsmeier , '24, Hillary Kim , '25, Allison N. Miller

Mathematics & Statistics Faculty Works

A pattern knot in a solid torus defines a self-map of the smooth knot concordance group. We prove that if the winding number of a pattern is even but not divisible by 8, then the corresponding map is not a homomorphism, thus partially establishing a conjecture of Hedden.

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Ole Miss Recognizes Record Group Of Stamps Impact Prize Winners, Clara Turnage Aug 2025

Ole Miss Recognizes Record Group Of Stamps Impact Prize Winners, Clara Turnage

University of Mississippi News

OXFORD, Miss. – The Stamps Impact Prize welcomed its largest cohort yet of University of Mississippi student researchers and artists on Thursday (Aug. 28).

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Low Economic Level And The Risk Of Overweight Among Indonesian Junior And Senior High School Students, Ariyanto Nugroho, Purwo Setiyo Nugroho, Amarin Yudhana, Sri Sunarti Aug 2025

Low Economic Level And The Risk Of Overweight Among Indonesian Junior And Senior High School Students, Ariyanto Nugroho, Purwo Setiyo Nugroho, Amarin Yudhana, Sri Sunarti

Kesmas

Overweight and obesity among Indonesian adolescents have emerged as a pressing public health issue, reflecting global trends. This study examines the relationship between economic status and overweight prevalence among junior and senior high school students in Indonesia, using secondary data from the Global School-based Health Survey (GSHS). This study analyzed data from 9,977 students aged 11–18 years through a cross-sectional design and binary logistic regression, adjusting for dietary habits, physical activity, and sedentary behavior. Overall, 14.7% of students were overweight; the prevalence was notably higher among low-income students (27.4%) compared to high-income groups (14.2%). Students from lower economic backgrounds were …

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Hurricane Katrina Archive: Faculty Publications Bibliography 2010-2014, Lsu Health Sciences Center - New Orleans Libraries, Sharon Duffy, Matthew Folse Aug 2025

Hurricane Katrina Archive: Faculty Publications Bibliography 2010-2014, Lsu Health Sciences Center - New Orleans Libraries, Sharon Duffy, Matthew Folse

LSUHSC Hurricane Katrina Archive: Bibliographies

This bibliography includes 45 articles about Hurricane Katrina written by authors affiliated with LSU Health – New Orleans between January 2010 and December 2014.

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Hurricane Katrina Archive: Faculty Publications Bibliography 2005-2009, Lsu Health Sciences Center - New Orleans Libraries, Sharon Duffy, Matthew Folse Aug 2025

Hurricane Katrina Archive: Faculty Publications Bibliography 2005-2009, Lsu Health Sciences Center - New Orleans Libraries, Sharon Duffy, Matthew Folse

LSUHSC Hurricane Katrina Archive: Bibliographies

This bibliography includes 91 articles about Hurricane Katrina written by authors affiliated with LSU Health – New Orleans between January 2005 and December 2009.

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Sociohydrodynamics: Data-Driven Modeling Of Social Behavior, Daniel S. Seara, Jonathan Colen, Michel Fruchart, Yael Avni, David G. Martin, Vincenzo Vitelli Aug 2025

Sociohydrodynamics: Data-Driven Modeling Of Social Behavior, Daniel S. Seara, Jonathan Colen, Michel Fruchart, Yael Avni, David G. Martin, Vincenzo Vitelli

Data Science Faculty Publications

Living systems display complex behaviors driven by physical forces as well as decision-making. Hydrodynamic theories hold promise for simplified universal descriptions of socially generated collective behaviors. However, the construction of such theories is often divorced from the data they should describe. Here, we develop and apply a data-driven pipeline that links micromotives to macrobehavior by augmenting hydrodynamics with individual preferences that guide motion. We illustrate this pipeline on a case study of residential dynamics in the United States, for which census and sociological data are available. Guided by Census data, sociological surveys, and neural network analysis, we systematically assess standard …

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Prediction-Powered Inference For Clinical Trials: Application To Linear Covariate Adjustment, Pierre-Emmanuel Poulet, Maylis Tran, Sophie Tezenas Du Montcel, Bruno Dubois, Stanley Durrleman, Bruno M. Jedynak Aug 2025

Prediction-Powered Inference For Clinical Trials: Application To Linear Covariate Adjustment, Pierre-Emmanuel Poulet, Maylis Tran, Sophie Tezenas Du Montcel, Bruno Dubois, Stanley Durrleman, Bruno M. Jedynak

Mathematics and Statistics Faculty Publications and Presentations

Prediction-powered inference (PPI) (Angelopoulos et al., Science 382(6671):669-674, 2023) and its subsequent development called PPI++ (Angelopoulos et al., 2023) provide a novel approach to standard statistical estimation, leveraging machine learning systems, to enhance unlabeled data with predictions. We use this paradigm in clinical trials. The predictions are provided by disease progression models, providing prognostic scores for all the participants as a function of baseline covariates. The proposed method would empower clinical trials by providing untreated digital twins of the treated patients while remaining statistically valid. The potential implications of this new estimator of the treatment effect in a two-arm randomized …

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Enhancing Reliable And Energy-Efficient Uav Communications With Ris And Deep Reinforcement Learning, Wasim Ahmad, Umar Islam, Abdulkadhem A. Abdulkadhem, Babar Shah, Fernando Moreira, Ali Abbas Aug 2025

Enhancing Reliable And Energy-Efficient Uav Communications With Ris And Deep Reinforcement Learning, Wasim Ahmad, Umar Islam, Abdulkadhem A. Abdulkadhem, Babar Shah, Fernando Moreira, Ali Abbas

All Works

The rapid growth in wireless communication demands has led to a surge in research on technologies capable of enhancing communication reliability, coverage, and energy efficiency. Among these, uncrewed aerial vehicles (UAV) and reconfigurable intelligent surfaces (RIS) have emerged as promising solutions. Prior research on using deep reinforcement learning (DRL) to integrate RIS with UAV concentrated on enhancing signal quality and coverage, but it ignored the challenges caused by electromagnetic interference (EMI). This article introduces a novel framework addressing the challenges posed by EMI from Gallium nitride (GaN) power amplifiers in RIS-assisted UAV communication systems. By integrating DRL with quadrature phase …

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Symmetrically Threaded Superconducting Quantum Interference Devices As Next-Generation Kerr-Cat Qubits, Bibek Bhandari, Irwin Huang, Ahmed Hajr, Kagan Yanik, Bingcheng Qing, Ke Wang, David I. Santiago, Justin Dressel, Irfan Siddiqi, Andrew N. Jordan Aug 2025

Symmetrically Threaded Superconducting Quantum Interference Devices As Next-Generation Kerr-Cat Qubits, Bibek Bhandari, Irwin Huang, Ahmed Hajr, Kagan Yanik, Bingcheng Qing, Ke Wang, David I. Santiago, Justin Dressel, Irfan Siddiqi, Andrew N. Jordan

Mathematics, Physics, and Computer Science Faculty Articles and Research

Kerr-cat qubits are bosonic qubits offering autonomous bit-flip protection, traditionally studied using driven superconducting nonlinear asymmetric inductive element (SNAIL) oscillators. Here, we theoretically explore an alternative circuit for Kerr-cat qubits based on symmetrically threaded superconducting quantum interference devices (SQUIDs). The symmetrically threaded SQUID (STS) architecture employs a simplified flux-pumped design that suppresses two-photon dissipation, a dominant loss mechanism in high-Kerr regimes, by engineering the drive Hamiltonian’s flux operator to generate only even-order harmonics. By fulfilling two critical criteria for practical Kerr-cat qubit operation, the STS emerges as an ideal platform: (1) a static Hamiltonian with diluted Kerr nonlinearity (achieved via …

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Awake And Alive: An Investigation Into Content For A Music Course Incorporating The Sciences, Harrison Boraas Aug 2025

Awake And Alive: An Investigation Into Content For A Music Course Incorporating The Sciences, Harrison Boraas

Masters Theses

The purpose of this qualitative, instrumental case study was to identify the content for an interdisciplinary course about music and the brain that educates collegiate students about the benefits of lifelong music engagement. Despite increasing awareness of musical relevance to the human brain, many institutions of higher learning continue to teach music as its isolated area of study without connecting it to other fields that could benefit from incorporating it or vice versa. The sample size consisted of four to seven experts that were either community experts or Liberty University faculty in the fields of science, medicine, or music within …

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Molecular Dynamics Simulations Of Liposomes: Structure, Dynamics, And Applications, Ehsan Khodadadi, Ehsaneh Khodadadi, Parth Chaturvedi, Mahmoud Moradi Aug 2025

Molecular Dynamics Simulations Of Liposomes: Structure, Dynamics, And Applications, Ehsan Khodadadi, Ehsaneh Khodadadi, Parth Chaturvedi, Mahmoud Moradi

Chemistry & Biochemistry Faculty Publications and Presentations

Liposomes are nanoscale, spherical vesicles composed of phospholipid bilayers, typically ranging from 50 to 200 nm in diameter. Their unique ability to encapsulate both hydrophilic and hydrophobic molecules makes them powerful nanocarriers for drug delivery, diagnostics, and vaccine formulations. Several FDA-approved formulations such as Doxil (R) (Baxter Healthcare Corporation, Deerfield, IL, USA), AmBisome (R) (Gilead Sciences, Inc., Foster City, CA, USA), and Onivyde (R) (Ipsen Biopharmaceuticals, Inc., Basking Ridge, NJ, USA) highlight their clinical significance. This review provides a comprehensive synthesis of how molecular dynamics (MD) simulations, particularly coarse-grained (CG) and atomistic approaches, advance our understanding of liposomal membranes. We …

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