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Inter-Cellular Forces Modulate Cell-Ecm Traction Forces, Zaria Booth Aug 2025

Inter-Cellular Forces Modulate Cell-Ecm Traction Forces, Zaria Booth

Mechanical & Aerospace Engineering Theses & Dissertations

Epithelial cells are among the most abundant cell types in the human body, making up sheets of epithelial tissues that cover the linings of organs and body cavities. Cellular adhesion and force transmission across epithelial tissues are crucial in maintaining tissue integrity and ensuring proper tissue regeneration. Defects in cellular force transmission have been found in various diseases, including cancer. Force transmission at cell-cell and cell-ECM junctions drive cell survival and development. It has been previously shown that changes in cell-ECM traction directly modulates forces at cell-cell contacts. In this study, we aim to determine the effects of perturbations in …


'Managed Hearts’ In Helper-Education: Gender Non-Binary Helper-Educators’ Experiences Of Emotional Labor, Jordan Pearce Aug 2025

'Managed Hearts’ In Helper-Education: Gender Non-Binary Helper-Educators’ Experiences Of Emotional Labor, Jordan Pearce

Counseling & Human Services Theses & Dissertations

The unique experiences of people who identify with a gender beyond the binary paradigm dominant in the Global West are not well understood. The literature provides little insight into the experiences and perspectives of these individuals in a variety of contexts, including in their workplaces. As various social movements collide, they bring amplified attention to the mental health of marginalized communities and to workers, as well as the dynamics of modern work environments, and the specific needs of certain individuals doing certain types of work. The current study explored the experiences of gender non-binary individuals (GNI) working as helper-educators engaged …


Influence Of Mixing Duration And Absorption Characteristics Of Superabsorbent Polymers On The Fresh And Hardened Properties Of High-Performance Concrete, Yu Cun Gu, Kamal H. Khayat Aug 2025

Influence Of Mixing Duration And Absorption Characteristics Of Superabsorbent Polymers On The Fresh And Hardened Properties Of High-Performance Concrete, Yu Cun Gu, Kamal H. Khayat

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

This study investigates the combined influence of superabsorbent polymers (SAPs) with distinct absorption kinetics and extended mixing sequences on the rheological, mechanical, and transport properties of high-performance concrete (HPC). Two SAPs—an ionic acrylamide-co-acrylic acid copolymer (SAP-P) and a non-ionic acrylamide polymer (SAP-B)—were incorporated at an internal curing level of 100%. The impact of extended mixing times (3, 5, and 7 min) following SAP addition was systematically evaluated. Results showed that longer mixing durations led to increased superplasticizer demand and higher plastic viscosity due to continued water absorption by SAPs. However, yield stress remained relatively stable owing to the dispersing effect …


Modification Of Tini Alloy By Fast Pulse Laser Heat Treatment, Yitao Chen, Mohammad Masud Parvez, Frank Liou Aug 2025

Modification Of Tini Alloy By Fast Pulse Laser Heat Treatment, Yitao Chen, Mohammad Masud Parvez, Frank Liou

Mechanical and Aerospace Engineering Faculty Research & Creative Works

In this study, the effects of local heat treatment with fast pulse laser on thin TiNi shape memory alloy strip materials were investigated. Various materials characterization methods including optical microscope, scanning electron microscope, atomic force microscope, X-ray diffraction, differential scanning calorimetry, and Vickers hardness were used to identify the differences of microstructure, mechanical properties, and functional properties between regions inside and outside the laser-scanned region. The tensile test was also conducted for both the non-laser-scanned specimen and the laser-scanned specimen. The area covered by laser scanning shows great differences by possessing a more homogeneous austenite phase without shear bands and …


Digital Twins, Ai, And Cybersecurity In Additive Manufacturing: A Comprehensive Review Of Current Trends And Challenges, Md Sazol Ahmmed, Laraib Khan, Muhammad Arif Mahmood, Frank Liou Aug 2025

Digital Twins, Ai, And Cybersecurity In Additive Manufacturing: A Comprehensive Review Of Current Trends And Challenges, Md Sazol Ahmmed, Laraib Khan, Muhammad Arif Mahmood, Frank Liou

Mechanical and Aerospace Engineering Faculty Research & Creative Works

The development of Industry 4.0 has accelerated the adoption of sophisticated technologies, including Digital Twins (DTs), Artificial Intelligence (AI), and cybersecurity, within Additive Manufacturing (AM). Enabling real-time monitoring, process optimization, predictive maintenance, and secure data management can redefine conventional manufacturing paradigms. Although their individual importance is increasing, a consistent understanding of how these technologies interact and collectively improve AM procedures is lacking. Focusing on the integration of digital twins (DTs), modular AI, and cybersecurity in AM, this review presents a comprehensive analysis of over 137 research publications from Scopus, Web of Science, Google Scholar, and ResearchGate. The publications are categorized …


Examining The Impact Of A Utility Value Intervention On Self-Regulated Learning Engagement, Wanda D. Brooks Aug 2025

Examining The Impact Of A Utility Value Intervention On Self-Regulated Learning Engagement, Wanda D. Brooks

STEMPS Theses & Dissertations

The purpose of this study was to examine the impact of inserting a motivation intervention into a self-regulated learning training in an introductory biology course to increase academic performance and persistence to degree completion in science. The study was an experimental design with pre- and post-tests, with treatment and comparison groups. The training was in the form of three self-regulated learning cycles presented to students on a Blackboard Organization site where students were asked to record self-regulated learning activities in a journal during training. The primary aim of the intervention was to increase engagement in the self-regulated learning training by …


Valorizing Cement Kiln Dust And Glass Powder: A Binder Study On Sustainable Partial Cement Replacement, Sai Kiran Simhadri Aug 2025

Valorizing Cement Kiln Dust And Glass Powder: A Binder Study On Sustainable Partial Cement Replacement, Sai Kiran Simhadri

Civil & Environmental Engineering Theses & Dissertations

The production of cement ranks as a major source of global CO₂ emissions because of the high energy requirements needed to create clinker. The construction industry is actively seeking ways to reduce its carbon footprint. Utilizing industrial waste materials to partially replace cement can lower emissions. This research evaluates a ternary binder system which uses Cement Kiln Dust (CKD) and Glass Powder (GP) to replace a portion of Type IL (Portland Limestone) cement. The mixes were made with a fixed water-to-binder ratio of 0.44 and contained 15% GP by mass while the CKD content ranged from 0% to 10%. The …


Enhancing The Design Of Strained Superlattice Gallium Arsenide Based Photocathodes With Distributed Bragg Reflector, Adam D. A. Masters Aug 2025

Enhancing The Design Of Strained Superlattice Gallium Arsenide Based Photocathodes With Distributed Bragg Reflector, Adam D. A. Masters

Electrical & Computer Engineering Theses & Dissertations

Particle accelerators play a crucial role in our understanding of matter and the universe and have numerous practical applications in various fields. These devices enable scientists to examine the smallest components of matter, study the forces that govern their interactions, and probe conditions from the early universe. Moreover, accelerators are valuable in medicine, industry, and research, enhancing imaging methods, cancer therapies, and manufacturing techniques. As the experiments conducted at these facilities evolve and require higher precision, improved particle sources must continue to advance to keep up with their requirements. To do that, we enhanced the design of spin polarized electron …


Draining Development: The Changing Nature Of Corruption In Post-Independence India, Chandra Tiwari Aug 2025

Draining Development: The Changing Nature Of Corruption In Post-Independence India, Chandra Tiwari

Graduate Program in International Studies Theses & Dissertations

The economic growth of emerging economies, particularly India’s, stands at a crossroads as the fight against corruption intensifies. Corruption poses a significant threat to the overall development of a country, necessitating the convergence of technological advances with national and global initiatives to combat the issue. Despite several ongoing efforts taken by international bodies to enforce regulations, challenges persist in curbing this issue due to the fundamental behavioral and structural factors at play. This dissertation investigates the dynamic evolution of corruption within a cash-based economy, a period of trade openness, and the contemporary digitalized age in India through a comparative case …


Persistence And Completion Rates Of Community College Students: The Impact Of Receptivity To Social Engagement Scores Compared To Recorded Cocurricular Activity, Nancy Wagner Boylan Aug 2025

Persistence And Completion Rates Of Community College Students: The Impact Of Receptivity To Social Engagement Scores Compared To Recorded Cocurricular Activity, Nancy Wagner Boylan

Educational Leadership & Workforce Development Theses & Dissertations

This study examined the relationship between Ruffalo Noel Levitz College Student Inventory Receptivity to Social Engagement scores and the persistence and completion of community college students. The Ruffalo Levitz College Student Inventory assesses student receptivity to institutional support services. Receptivity scores indicate a student's willingness to accept help in areas such as academic support and social engagement as well as career and financial guidance.

This research explored the impact of documented cocurricular involvement, measured through student activities indicators, on persistence and completion outcomes. Using ex post facto data and binary logistic regression analyses, the research focused on three populations at …


Engineering Tunable Collagen Fiber Alignment Gradients To Quantify Contact Guidance Effects On Cell Migration, Indranil Mandar Joshi Aug 2025

Engineering Tunable Collagen Fiber Alignment Gradients To Quantify Contact Guidance Effects On Cell Migration, Indranil Mandar Joshi

Theses

Directional migration of cells is one of the most important physiological processes, necessary for tissue and organ development. It also plays a crucial role in pathological conditions such as cancer metastasis. This directed migration is influenced by various factors present in the native environment, which guide cells to migrate steadily in a specific direction. Due to its importance, over the years, a lot of emphasis has been placed on understanding and exploring the biochemical and biophysical factors that direct cell migration. In addition to the commonly studied biochemical and biophysical cues, contact guidance from collagen fibers, in the native matrix, …


A Place To Pause: Designing Ritual Space In The Domestic Realm, Elise Miller Aug 2025

A Place To Pause: Designing Ritual Space In The Domestic Realm, Elise Miller

Theses

Modern society in Western developed countries is focused on the rush and go, often leaving people feeling discombobulated from constant running around, task-oriented days and switching of roles one must play in different areas of their life, such as at home, work, socializing, parenting, etc. How can ritual bring a sense of calmness and order to lives of those on the go? Ritual studies are often only categorized under psychology, sociology, or religious studies. However, as industrial design encompasses human interaction with objects, often with an emotional quality, ritual can be studied more wholesomely with the added lens of industrial …


Design That Builds Communitites: An Evaluation Method For Analyzing, Assessing, And Improving The Way We Plan And Design The Places Around Us, Devine Karas-Gonzalez Aug 2025

Design That Builds Communitites: An Evaluation Method For Analyzing, Assessing, And Improving The Way We Plan And Design The Places Around Us, Devine Karas-Gonzalez

Theses

The places around us shape and impact on the way we interact and live within our communities. As such, it is important to place greater emphasis on designing spaces which are meant to better respond to the needs and functions of a place. With an architectural design process this will result in the use of design strategies which will inform much of the design. In this research, multiple design strategies (Smart Growth, Placemaking, Place Value, and Street Experiments) are evaluated and compared using four regionally similar cities to analyze and assess how the different strategies impact the design process by …


Haunted Echoes, Stuti Kasat Aug 2025

Haunted Echoes, Stuti Kasat

Theses

Haunted Echoes explores the narrative and emotional possibilities of interactive digital fiction by creating a room-based haunted experience. By placing the users within a haunted manor the project encourages emotional discovery through narrative exploration. As a room-based exploratory experience, users get to navigate a dollhouse-style 3D interface, interacting with objects to reveal layered micro-stories and uncover the manor’s haunted past. The experience turns spatial exploration into emotional discovery, drawing inspiration from immersive theater, point-and-click adventures, and environmental storytelling in video games. The thesis examines the intersection and overlap of interactive storytelling, visual communication, and emotional immersion, integrating 3D modeling (Blender/Cinema …


Kinematic Confirmation Of A Remarkable Linear Trail Of Galaxies In The Ngc 1052 Field, Consistent With Formation In A High-Speed Bullet Dwarf Collision, Michael A. Keim, Pieter Van Dokkum, Zili Shen, Harrison Souchereau, Imad Pasha, Shany Danieli, Roberto Abraham, Aaron J. Romanowsky, Yimeng Tang Aug 2025

Kinematic Confirmation Of A Remarkable Linear Trail Of Galaxies In The Ngc 1052 Field, Consistent With Formation In A High-Speed Bullet Dwarf Collision, Michael A. Keim, Pieter Van Dokkum, Zili Shen, Harrison Souchereau, Imad Pasha, Shany Danieli, Roberto Abraham, Aaron J. Romanowsky, Yimeng Tang

Faculty Research, Scholarly, and Creative Activity

A unique linear trail of diffuse galaxies was recently identified in the NGC 1052 field. This trail includes the remarkable, ultradiffuse galaxies DF2 and DF4, which lack dark matter and host unusually luminous globular clusters. It has been proposed that the trail formed via a high-speed collision between two gas-rich dwarf galaxies. This scenario predicts that the trail galaxies are kinematically connected and follow a specific trend in radial velocity as a function of position, based on the known velocities and positions of DF2 and DF4. To test this hypothesis, we measured radial velocities for seven additional galaxies on the …


Anticolonialism And Qualitative Methods For Culture-Centered Interventions, Mohan Jyoti Dutta, Ambar Basu, Satveer Kaur-Gill, Debalina Dutta, Mahuya Pal, Iccha Basnyat, Selina Metuamate, Venessa Pokaia, Phoebe Elers, Indranil Mandal, Rabindranath Mandi, Pankaj Baskey, Devalina Mookerjee, Shaunak Sastry, Jaime Robb, Andrew Carter Aug 2025

Anticolonialism And Qualitative Methods For Culture-Centered Interventions, Mohan Jyoti Dutta, Ambar Basu, Satveer Kaur-Gill, Debalina Dutta, Mahuya Pal, Iccha Basnyat, Selina Metuamate, Venessa Pokaia, Phoebe Elers, Indranil Mandal, Rabindranath Mandi, Pankaj Baskey, Devalina Mookerjee, Shaunak Sastry, Jaime Robb, Andrew Carter

Faculty Research, Scholarly, and Creative Activity

In this essay, we a collective of Indigenous, Black, and migrant Global South scholars engaged in experiments with the culture-centered approach (CCA) draw on our lived experiences amidst struggles against land grab, neoliberal extractivism, and capitalist exploitation to outline a framework for qualitative methods as anticolonial politics. We begin by exploring the interplays of colonialism, imperialism, and racial capitalism that have shaped the origins and uses of qualitative methods toward serving extractive agendas of global capital. This critique serves as the basis for outlining the key principles of the CCA, turning to voice, storytelling, and embodied action as the basis …


Dynamic Mode Decomposition Of Geostrophically Balanced Motions From Swot Cal/Val In The Separated Gulf Stream, Takaya Uchida, Badarvada Yadidya, Karl E. Lapo, Xiaobiao Xu, Jeffrey J. Early, Brian K. Arbic, Dimitris Menemenlis, Luna Hiron, Eric P. Chassignet, Jay F. Shriver, Maarten C. Buijsman Aug 2025

Dynamic Mode Decomposition Of Geostrophically Balanced Motions From Swot Cal/Val In The Separated Gulf Stream, Takaya Uchida, Badarvada Yadidya, Karl E. Lapo, Xiaobiao Xu, Jeffrey J. Early, Brian K. Arbic, Dimitris Menemenlis, Luna Hiron, Eric P. Chassignet, Jay F. Shriver, Maarten C. Buijsman

Faculty Research, Scholarly, and Creative Activity

The decomposition of oceanic flow into its geostrophically balanced and unbalanced motions carries theoretical and practical significance for the oceanographic community. These two motions have distinct dynamical characteristics and affect the transport of tracers differently from one another. The launch of the Surface Water and Ocean Topography (SWOT) satellite provides a prime opportunity to diagnose the surface balanced and unbalanced motions on a global scale at an unprecedented spatial resolution. Here, we apply dynamic-mode decomposition (DMD), a linear-algebraic data-driven method, to tidally-forced idealized and realistic numerical simulations at submesoscale-permitting resolution and one-day-repeat SWOT observations of sea-surface height (SSH) in the …


Assessing And Developing Higher Education Faculty Digital Competency For Workplace Preparation In A Digital Society, Yolanda T. Martinez Aug 2025

Assessing And Developing Higher Education Faculty Digital Competency For Workplace Preparation In A Digital Society, Yolanda T. Martinez

Electronic Theses and Dissertations

A shared global theme across higher education institutions is the need for training and development regarding digital competencies for higher education, yet there are little to no digital competency frameworks for faculty at higher educational institutions, like there are for K12. What can leaders in higher educational institutions do to prepare adult learners for a digital society and workplace that continues to expand globally in every field? Should every school adopt XYZ College’s approach, where leadership collaborated and developed an emerging technologies academy (ETA) to provide support and training on emerging technologies provided and supported by the college to self-enrolled …


Electronic Health Record Downtime, Grace R. Baldauf Aug 2025

Electronic Health Record Downtime, Grace R. Baldauf

Electronic Theses and Dissertations

Electronic health record (EHR) downtime presents significant challenges to patient safety and care quality in acute care settings, particularly regarding timely medication administration. This project addressed the problem of late or absent medication doses during planned or unplanned EHR downtime. The investigator aimed to evaluate the effectiveness of a structured downtime plan in improving nurses’ ability to administer medications on time during periods of EHR unavailability. The investigator used a quantitative design to implement a downtime plan evaluation paradigm. Data were collected using retrospective chart reviews of medication administration records pre-implementation and postimplementation of the downtime plan. The sample included …


Perceived Leadership Behaviors And Workplace Motivation: The Predictive Role Of Generational Cohorts In The U.S. Construction Industry, Leslie D. Klinegardner Aug 2025

Perceived Leadership Behaviors And Workplace Motivation: The Predictive Role Of Generational Cohorts In The U.S. Construction Industry, Leslie D. Klinegardner

Electronic Theses and Dissertations

The purpose of this study was to examine the extent to which perceived leadership behaviors predicted workplace motivation among construction workers across generational cohorts in the Greater Houston, Texas area. Grounded in self-determination theory, the research explored how transformational, transactional, and passive-avoidant leadership behaviors predicted the satisfaction and frustration of psychological needs for autonomy, competence, and relatedness. The analysis also considered whether leadership behaviors and generational cohort served as significant predictors of workplace motivation outcomes. The study followed a quantitative, predictive, cross-sectional design using survey methodology. Data were collected using the Multifactor Leadership Questionnaire (MLQ) and the Basic Psychological Need …


The Danger Of Dobbs: Substantive Due Process, Fundamental Rights, And A Critique Of The Theory Of Historical Tradition, Parker J. Wilkson Aug 2025

The Danger Of Dobbs: Substantive Due Process, Fundamental Rights, And A Critique Of The Theory Of Historical Tradition, Parker J. Wilkson

University of Florida Journal of Law & Public Policy

Central to the Supreme Court’s holding in Dobbs v. Jackson Women’s Health Organization that the right to obtain an abortion would no longer be recognized as a fundamental right is the theory of historical tradition: the view that the only liberty interests recognized as fundamental rights under the Due Process Clause are those that are “deeply rooted in this Nation’s history and tradition.” This Note argues that the theory of historical tradition should not set the outer boundaries of fundamental rights. In demanding that a fundamental right find support in the Nation’s history and tradition, the Supreme Court imports a …


Delayed & Denied: How One Court's Interpretation Of Emtala Obstructs Emergency Abortion Care & Threatens Women's Health, Christina Dalton Aug 2025

Delayed & Denied: How One Court's Interpretation Of Emtala Obstructs Emergency Abortion Care & Threatens Women's Health, Christina Dalton

University of Florida Journal of Law & Public Policy

This Note addresses whether EMTALA preempts state abortion bans in the context of a medical emergency. Part I provides background information on the Dobbs decision and how states responded, discusses the Department of Health and Human Services’ interpretation of EMTALA’s preemptive effect, and introduces the competing district court cases. Notably, the analysis of these district court cases focuses on the relevant state abortion bans as they existed at the time of each decision. Part II discusses EMTALA, specifically Congress’ intent in enacting the statute and the obligations it imposes on hospitals and physicians. Part III then provides an overview of …


Embryos On Ice: Issues With Estate Law And Assisted Reproduction In A Post-Dobbs World, Nicole Pomerantz Aug 2025

Embryos On Ice: Issues With Estate Law And Assisted Reproduction In A Post-Dobbs World, Nicole Pomerantz

University of Florida Journal of Law & Public Policy

Will you have to share your property interests with an embryo in a petri dish? This Note explores the complex legal landscape surrounding the estate interests of cryopreserved embryos in the wake of the Supreme Court’s decision in Dobbs v. Jackson Women’s Health Organization. The piece delves into the implications of recognizing embryos as legal persons with rights, particularly in the context of estate law, where the classification of embryos can significantly impact property distribution, class-closing rules, and the application of the Rule Against Perpetuities. By examining case law, statutes, and the potential consequences of states adopting the Dobbs …


Vol 70 #4, Rebecca Chavez Aug 2025

Vol 70 #4, Rebecca Chavez

MPLA Newsletter

No abstract provided.


Will The Court Use Dobbs To Overturn Sullivan? Revisiting The Sullivan Decision In The Age Of Digital Media, Skylar Tess Ivey Detjen Aug 2025

Will The Court Use Dobbs To Overturn Sullivan? Revisiting The Sullivan Decision In The Age Of Digital Media, Skylar Tess Ivey Detjen

University of Florida Journal of Law & Public Policy

New York Times Co. v. Sullivan is a landmark Supreme Court decision that significantly expanded protection for the press under the First Amendment by limiting public officials’ ability to sue for defamation. The ruling established the “actual malice” standard, requiring public officials to prove that defamatory statements were made with knowledge of their falsity or with reckless disregard for the truth. In recent years, Justice Thomas has repeatedly criticized Sullivan, arguing that the decision is more a product of judicial policymaking than of constitutional interpretation, with minimal grounding in the text or history of the First or Fourteenth Amendments. …


Rheumatic Heart Disease In Primary Aged Children In Samoa, Kallysta Lindquist Aug 2025

Rheumatic Heart Disease In Primary Aged Children In Samoa, Kallysta Lindquist

Undergraduate Honors Theses

Rheumatic heart disease (RHD) is a condition where the heart valves are permanently damaged by an autoimmune response to chronic strep infections. RHD remains extremely prevalent in Oceania - specifically Samoa. However, despite its prevalence, RHD is underexplored in Samoa and there are many disparities for medical care to treat RHD in Samoa. This research shifts the focus of RHD to early detection in children (5-18 years old) and provides critical insights into RHD and the geographic difference in RHD prevalence in Samoa. Our dataset was collected between 2013-2019 from the Rheumatic Relief program done by Brigham Young University. Data …


Oral History Of Dr. Carl Jón Denbow, Director Of Information For The College Of Osteopathic Medicine Conducted On 02/20/2025 By Angel David García García, Carl Jón Denbow, Angel David García García Aug 2025

Oral History Of Dr. Carl Jón Denbow, Director Of Information For The College Of Osteopathic Medicine Conducted On 02/20/2025 By Angel David García García, Carl Jón Denbow, Angel David García García

HIST 4798/5798: Recording Memory: Methods and Uses of Oral History

Dr. Carl Jón Denbow discusses his history, how he became the Director of information for the College of Osteopathic Medicine at Ohio University, and his time in this position.

This interview was conducted as part of a class project for Recording Memory: Methods and Uses of Oral History, Spring 2025, Alexander G. Lovelace (Ph.D.) Instructor


Reducing Single-Use Plastic In Georgetown County, Alex Gaspar Aug 2025

Reducing Single-Use Plastic In Georgetown County, Alex Gaspar

Goal 12: Responsible Consumption and Production

No abstract provided.


Association Between Social Participation And Nonmotor Symptoms Of Parkinson's Disease, Zackary B. Zanotelli Aug 2025

Association Between Social Participation And Nonmotor Symptoms Of Parkinson's Disease, Zackary B. Zanotelli

Electronic Theses, Projects, and Dissertations

Research has shown that social participation can aid in slowing cognitive decline and is associated with cognitive functioning in older adults. Being that Parkinson’s Disease (PD) is a neurodegenerative disorder primarily known for its motor and cognitive symptoms, it is worth evaluating social participation in patients with Parkinson’s Disease. The aim of this project is to determine whether social participation is associated with more favorable trajectories of neuropsychiatric symptoms among patients afflicted with Parkinson’s Disease. More specifically, this project will seek to examine how specific social activities may be uniquely associated with cognitive decline.

Participants (N = 8,389) who were …


Transfusion-Related Acute Lung Injury (Trali): Current Understanding, Challenges, And Future Directions, Fahd A. Kuriri Aug 2025

Transfusion-Related Acute Lung Injury (Trali): Current Understanding, Challenges, And Future Directions, Fahd A. Kuriri

Saudi Medical Journal

ABSTRACT Transfusion-related acute lung injury (TRALI) remains one of the most serious yet often overlooked complications of blood transfusion, contributing to significant morbidity and mortality worldwide. It manifests as acute respiratory distress and non-cardiogenic pulmonary edema within 6 hours of transfusion, requiring immediate recognition and intervention. However, diagnosing TRALI is complex, as its clinical presentation overlaps with other causes of acute lung injury, and its underlying mechanisms remain incompletely understood. This review examines the global burden of TRALI, shedding light on underreporting issues, particularly in resource-limited settings where surveillance systems are inadequate. It explores both antibody-dependent and antibody-independent pathways, focusing …