Digital Commons Network^™

Using Exercise To Treat Anxiety In Adult Patients With Addiction, Emmanuella N. Nnadozie

Walden Dissertations and Doctoral Studies

Summary In this Doctor of Nursing Practice (DNP) project, I selected a staff education as the best intervention to improve staff knowledge in using exercise to treat anxiety disorders in adult patients at a recovery clinic for addiction. Anxiety disorders are highly prevalent among individuals undergoing substance abuse treatment, often exacerbating withdrawal symptoms and increasing relapse risks; thus, integrating the use of exercise in addition to existing standard care for anxiety treatment in individuals with substance use disorder (SUD) will lead to decreased anxiety, decreased alcohol use and drug cravings, improved quality of life and affect, increased abstinence, and improve …

The Implications Of Insecure Use Of Fonts Against Pdf Documents And Web Pages, Junjie Xiong, Mingkui Wei, Xiao Han, Zhuo Lu, Yao Liu

Computer Science Faculty Research & Creative Works

This paper identifies the importance of the safe use of fonts in web and document security. We find multiple attack surfaces that can be exploited by an adversary using malicious fonts. We conduct a comprehensive evaluation of Portable Document Format (PDF) documents collected from the real world to investigate how an attacker can bypass PDF signatures. We further evaluate the potential security threats that an attacker can bring to web-based emails. Our study shows that various security issues may be caused by the inappropriate use of fonts, which are nevertheless overlooked in the past years. As such, guidelines promoting the …

Instability Of The Octahedral Symmetry In Si8o12h8 And Ge8o12h8: A Consequence Of The Pseudo-Jahn–Teller Effect, Jules Tshishimbi Muya, Arnout Ceulemans, Carol A. Parish

Chemistry Faculty Publications

The symmetry breaking in octahedral silsesquioxane and its germanium analogues (Si8O12H8 and Ge8O12H8) has been investigated using the M06-2X/6-31++G(3df, 3pd) method and group theory. Both structures undergo  symmetry breaking, characterized by pseudo-Jahn−Teller stabilization energies of 0.22 kcal/mol for Si-POSS and 9.82 kcal/mol for Ge-POSS. Under the influence of the pseudo-Jahn–Teller effect, the distortion vector involves the vibrational a2g mode with imaginary frequency. The distortion forces in Oh-POSS are predominantly localized on the oxygen atoms and driven by the coupling between the lowest unoccupied molecular orbital (a1g) and the highest occupied molecular orbital (a2g). The symmetry breaking is attributed to a …

Mechanisms Of Ssdna Gap Resection In Brca1-Proficient And -Deficient Cells, Isabelle Seppa

Arts & Sciences Graduate Student Theses and Dissertations

Single-stranded (ss) DNA gaps are potentially genome-destabilizing structures that require prompt repair (or filling) to prevent DNA breakage and genome instability. We previously showed that gap repair is defective in cancer cells with deficiencies in the breast cancer susceptibility gene BRCA1. These findings explain why ssDNA gaps accumulate in BRCA1-deficient cells in response to therapies that target DNA, such as platinum-based compounds, or therapies that inhibit specific repair pathways, such as PARP inhibitors (PARPi). We also discovered that gap repair can be restored in BRCA1-deficient cells by inhibiting MRE11 nuclease activity, indicating that nuclease processing plays a central role in …

Design And Evaluation Of An Electromagnetic Band Gap Structure For Self-Interference Reduction In Mmwave Full-Duplex Systems, Adewale Kehinde Oladeinde

Dissertations and Theses

Full-duplex (FD) wireless is a new technology that allows a device to transmit and receive at the same time and on the same frequency band. It has the potential to double the capacity and spectral efficiency of a wireless link compared to the family of conventional half-duplex wireless systems. The key challenge in implementing FD wireless communication is self-interference (SI): a node's transmitting signal generates significant interference to its receiver. Several previous studies have demonstrated the potential to reduce SI and develop FD radios; however, these studies are mostly limited to sub-6 GHz systems. Previous and on-going research explored various …

Advancing Autonomous Swarm Behavior In A Simulated Anti-Access Area Denial Environment, Chad Macwilkinson, Lance E. Champagne, Phillip M. Lacasse

Faculty Publications

This study proposes the application of a four dimensional framework of autonomy to a weapon swarm of high subsonic cruise missiles.

Two Decapod Crustaceans, Panopeus Herbstii And Petrolisthes Armatus, Stabilize Their Gaze Using Achromatic Visual Cues, But Not The Angle Of Linearly Polarized Light, M. Janakis, S. Guirges, A. C. Grant, I. Paris, E. F. Lopresti, Daniel Isaac Speiser

Faculty Publications

No abstract provided.

Factors That Influence Female Orthopaedic Surgeons' Decision To Pursue A Career In Sports Medicine: A Mixed-Methods Study, Nichelle M Enata, Katherine M Gerull, Ahmed Hanafy, Mary K Mulcahey, Derrick M Knapik, Matthew V Smith

2020-Current year OA Pubs

BACKGROUND: Despite the increased percentage of women in medical school and in orthopaedic residency programs, the percentage of women pursuing careers in sports medicine has only increased 3% over the past decade.

PURPOSE: To investigate the experiences and perceptions of female orthopaedic surgeons about sports medicine, identifying factors influencing career interest in this surgical subspecialty.

STUDY DESIGN: Cross-sectional study.

METHODS: A mixed-methods approach, combining an online survey and qualitative interviews, was utilized to compare the clinical experiences and personal perceptions of women in orthopaedic sports medicine with women in other orthopaedic subspecialties. Surveys were distributed to members of the Ruth …

A Potential New Sea Surface Temperature Proxy Based On Isomeric Highly Branched Isoprenoid Lipid Biomarkers: Ez25, Simon T. Belt, Lukas Smik, Katrine Husum, Jochen Knies

School of Geography, Earth and Environmental Sciences

Two tri-unsaturated and isomeric (E/Z) highly branched isoprenoid (HBI) diatom lipid biomarkers were quantified in 228 water column samples collected from the English Channel, West Svalbard (Arctic), the Scotia Sea (Southern Ocean) and East Antarctica. We found that the relative amounts of the two HBIs correlate well with water temperatures taken at the time of sampling. Based on these findings and some other HBI data reported previously, we suggest that the proportion of the HBI E-isomer (termed EZ25) may serve as a new proxy for palaeo sea surface temperatures, including in the polar regions. Next steps will involve determination of …

Asymmetric Fgf Receptor Dimerization: Implications For Fgf23 Biology And Drug Discovery, Mohammed S. Razzaque, Moosa Mohammadi

School of Medicine Publications

Fibroblast growth factor 23 (FGF23) requires both αKlotho and heparan sulfate proteoglycans (HSPGs) as obligatory coreceptors to bind, dimerize, and activate its FGF receptors (FGFRs) in the kidney, thereby regulating mineral ion and vitamin D homeostasis. Cryogenic electron microscopy studies reveal that FGF23 signaling proceeds through an asymmetric 1:2:1:1 FGF23–FGFR–αKlotho–HS assembly. According to this structural model, αKlotho simultaneously anchors FGF23 and one FGFR chain, referred to as the primary receptor (FGFRP), to form a 1:1:1 FGF23-FGFRP-αKlotho triplex, which boosts FGF23-FGFRP interaction. Subsequently, the HS coreceptor aids the triplex in recruiting a second FGFR chain, or secondary receptor (FGFRS), leading to …

Simulated Emergency Room Sign-Outs: What They Tell Us About Diagnostic Accuracy And Opportunities For Improvement, Nathan R Hoot, David J Robinson, Charles L Maddow, Amy Franklin

Faculty, Staff and Student Publications

Objective: Emergency department (ED) sign-outs provide continuity of care for patients at shift changes. However, these periods have been associated with communication breakdowns and medical errors. We explored information factors (stage-of-the-case and the explicitness of the sign-out narrative) to determine their impact on clinicians' diagnostic accuracy and confidence.

Methods: Clinicians from 2 academic ED sites reviewed patient vignettes sign-out narratives (N=69). Using a within-subjects experiment, the explicitness of the sign-out information (i.e., broad statement about labs versus stating each test) and the patient's stage in the diagnostic process (e.g., labs pending, treatment occurring, etc.) at the time of sign-out varied. …

Racial Differences In Global Satisfaction At A Predominantly White Regional Comprehensive University, Philip B. Mason, Michelle Petrie

Teacher-Scholar: The Journal of the State Comprehensive University

In the face of tightening state funding and increased reliance on tuition and growing enrollment, regional comprehensive universities continue to focus on the retention of students. Underserved students continue to represent areas of growth in college enrollment at regional comprehensive universities; yet these students are often at the highest risk of attrition. Overall institutional satisfaction is among the most useful indicators of student persistence, but research demonstrates that students of color report lower levels of overall satisfaction than their white counterparts. Scholarship on college student persistence documents several variables that predict higher retention, progression, and graduation rates among students. Research …

Assessing University Students’ Self-Reported Vocabulary Learning Strategy Use, Yirgalem Girma

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

Learning vocabulary is certainly a vital component of language learning and without this integral component of language communication becomes hardly meaningful. Thus, students are expected to have rich vocabulary power that enables them to communicate successfully via listening, speaking, reading, and writing; it assists students in expressing a range of meanings in various communicative situations for various purposes. This demands students to learn vocabulary using diverse vocabulary learning strategies that assist them in learning (internalizing, storing, recalling, and using) words properly. However, several students barely manage vocabulary learning tasks and/or use appropriate and diverse vocabulary in English classes. Consequently, this …

Teachers' Difficulty Factors In Implementing Differentiated Learning In Geography Subjects, Aulia Nindy Fadila Gastama

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

The implementation of differentiated learning in geography subjects provides benefits for teachers and students. On the other hand, teachers still have difficulty implementing differentiated learning elements. This research aims to analyze the factors related to teacher difficulties in implementing differentiated learning in geography subjects. The research method used descriptive qualitative research with semi-structured interviews. The informants used were geography teachers of SMAN Malang City. Data analysis was conducted by 1) data reduction, 2) data presentation, and 3) conclusion drawing. The results showed that geography teachers in Malang City State Senior High School faced difficulties in implementing differentiated learning. In content …

Targeted Depression Screening For At-Risk High School Students: An Integrated Review, Joseph Calub

DNP Qualifying Manuscripts

Depression in high school students is underrecognized because symptoms can present not only as mood issues but also behavioral or academic problems. This integrated review examined literature from 2010-2015 using PsycInfo, ERIC, CINAHL, and PubMed to evaluate the effectiveness of targeted depression screening for students referred for behavioral, academic, or social concerns. Studies meeting inclusion criteria assessed targeted or clinically referred screening methods, with a focus on validated tools such as the Patient Health Questionnaire modified for Adolescents (PHQ-A). Findings indicate that targeted screening effectively identifies depressive symptoms in at-risk students and is more feasible in resource-limited schools than universal …

Transition And Instability Characteristics Of The Separated Shear Layer Formed At Low Reynolds Number Over Three-Dimensional Irregular Rough Surface, Ganesh Kt Mr

Theses and Dissertations

The present experimental work investigates the effects of irregularly roughened surfaces and imposed streamwise pressure gradients on the topological, transitional, and instability characteristics of the laminar separated shear layer (SSL). Experiments are conducted in the low-speed wind tunnel for 𝑅𝑒𝑡=30000, based on the thickness of the airfoil model, t, and freestream turbulence intensity, fst = 0.8%. The airfoil model used in this study features a semicircular leading edge followed by a constant-thickness flat portion and a pitchable trailing-edge flap. Test conditions include two rough surfaces: sandblasted (SB) and sand-deposited (SD), and flap deflections: 𝛽=−30° and 𝛽=+30°, imposing adverse (APG) and …

Buddhism For Thinkers, Chang-Seong Hong, Sun Kyeong Yu

MSU Authors Collection

This book is an introduction to Buddhist philosophy. It uses the methods of analytic philosophy to approach the major topics of Buddhism.

Geotechnical Investigation Of Sand Flow Slides, Haines, Alaska, Christopher Kalev

Engineering

The Lutak Spur (LS) - a prominent glacio-deltaic landform located near Haines, Alaska - formed during the retreat of the Cordilleran Ice Sheet during the Last Glacial Maximum. This study evaluates its geologic evolution, soil development, and hydrologic-slope stability response to a December 2020 atmospheric river (AR) event, which triggered multiple slope failures. Geologic mapping and interpretation of previous work suggest that the LS formed as an ice­ contact kame delta at the margin of a retreating valley glacier. Following deglaciation, post­ glacial isostatic adjustment and sea-level changes exposed the LS surface, allowing for the development of Spodosols with iron-cemented …

Effect Of Climate Change On Arctic Water Quality, Karki Sarthak

Engineering

Climate change is fundamentally altering Arctic hydrological systems, impacting water quality and posing challenges for communities dependent on these vulnerable sources. This study examines water quality trends across three distinct Arctic contexts: (1) Arctic glaciers, (2) the Yukon River Basin (YRB), encompassing a five-year dataset (2019-2023) of dissolved organic carbon (DOC), sulfate, and stable water isotopes (δ2H, δ18O, and d-excess) across varying permafrost regions and seasons, and (3) Shishmaref, Alaska, where a washeteria-based drinking water system is affected by environmental and seasonal changes triggered by climate change and coastal erosion. By addressing both regional hydrology and community-specific challenges, the study …

Reanalysis And (Near) Real-Time Inversion Of Deformation Observations At Alaskan Volcanoes, Mario Fernando Angarita Vargas

Geosciences

Forecasting volcanic eruptions remains challenging due to the complexity and limited understand­ing of volcanic processes. However, recent studies have shown that integrating multidisciplinary data from past eruptions can improve forecasts for monitored volcanoes. The PREEVENTS project addresses this challenge identifying patterns prior, during or following volcanic eruptions on mul­tidisciplinary data. The project considers four disciplines: Geodesy, Petrology, Seismology and Gas/Geochemistry. This dissertation contributes with two novel tools to analyze geodetic data. The first tool exploits the amplitude from SAR imagery to quantify morphology changes during erup­tions. The tool has been verified with a synthetic case and validated with a dome …

Measuring Arctic Ground Squirrel Adult Neurogenesis In Caudal Hippocampus Using Dab/Dab-Ni Enzyme-Based Immunohistochemistry, Vy L. Nguyen

Chemistry and Biochemistry

Unconscious patients who are resuscitated after cardiac arrest often have a poor prognosis for neurological recovery and are routinely treated with therapeutic hypothermia as a standard of care. This intervention aims to reduce the risk of death and minimize brain damage. However, results from the Targeted Temperature Management 2 (TTM2) trial in 2021 indicate that cooling does not improve neurological outcomes in these patients. This finding raises questions about the neurological benefits, particularly regarding neurogenesis, of the rewarming phase of therapeutic hypothermia, as well as the effects of repeated cooling and rewarming cycles. Neurogenesis has been largely overlooked in therapeutic …

Understanding Secondary Atmospheric Chemistry In Extremely Cold And Dark Environments Through Hydroxymethanesulfonate (Hms) Measurements In Wintertime Fairbanks, Alaska, James R. Campbell

Chemistry and Biochemistry

Fairbanks, Alaska is a subarctic city that regularly violates PM2.5 air quality standards in the winter, exacerbated by strong wintertime inversion layers and wood stove heating. While primary sources of PM2.5 in Fairbanks have been studied extensively, secondary chemistry remains not well understood. Here, we focus on the aqueous secondary product hydroxymethanesulfonate (HMS), a major sulfur(IV) particulate species, to help understand what drives secondary pollution in Fairbanks. In 2020 and 2021, we used a particle-into-liquid sampler coupled with ion chromatography (PILS-IC) to measure HMS and sulfate concentrations. We report that HMS concentrations are high compared to other highly polluted regions …

Gwich'in Athabascan Storybook For Primary Classrooms: Integrating Alaska Native Language And Culture Into Language Arts Curriculum, Lin Vandyke

Education

The problem addressed by this project is the lack of high-quality children’s literature that accurately embodies Alaska Native culture, specifically Gwich’in Athabascan culture, that can be used in primary classrooms. The significance of this topic is the need for materials that Alaska Native students can connect with on a personal level and that can create a greater understanding of Native culture for all individuals. The work was completed in July of 2025. The important implications of this project are the availability of an easy-to-use storybook and connected resources to read with students and have quality discussions about Athabascan language and …

Alaska Earthquake Center Quarterly Review January-March 2025, Heather Mcfarlin, Will Dienstfrey, Alexandra Farrell, Beth Grassi, Stephen Holtkamp, Nate Murphy, Elisabeth Nadin, Carolyn Parcheta, Angelica Stabs, Michael West

Alaska Earthquake Center Reports

This series of technical quarterly reports from the Alaska Earthquake Center (AEC) includes detailed summaries and updates on Alaska seismicity, the AEC seismic network and stations, fieldwork, our online presence, public outreach, and lists publications and presentations by AEC staff. Multiple AEC staff members contributed to this report.

In Silico Investigations Of Class Ii Trans Activator (Ciita): Its Plausible Implications In Neuroinflammation And Neurological Disorders, Kishore N

Theses and Dissertations

Inflammation plays a significant role in maintaining homeostasis. Neuroinflammation is a chronic inflammatory response in the central nervous system (CNS), leading to brain or spinal cord dysfunction. To promote mental health, it is crucial to understand the regulation of neuroinflammation. Class II transactivator (CIITA) is a master-regulator of the major histocompatibility complex II (MHCII).

Modulation of CIITA has been suggested as a promising intervention for inflammatory conditions, including neurological disorders. However, there is limited knowledge about the role of CIITA and its interactors in inflammation. This study aimed to understand the role of CIITA in neuroinflammation and neurological disorders using …

Detailed Modelling And Analysis Of A Shake Table Comprising Hybrid Actuation And Load-Balancing Mechanism, Xavier Reni Prasad

Theses and Dissertations

Catastrophic earthquakes endanger human lives by severely damaging critical infrastructure such as nuclear plants, bio-laboratories, and bridges. Developing earthquake-resistant structures is vital to mitigate these risks. Shake tables replicate recorded earthquake ground motions to assess structural performance. This research presents a novel three-legged, six degrees of freedom (6-DOF) hybrid shake table with a cost-effective design and decoupled motion control, offering a viable alternative to conventional six-legged models.

This architecture effectively decouples actuator motions by employing hydraulic actuators for 3-DOF spatial movement and electromechanical actuators for 3-DOF planar motion. Servo-hydraulic actuators support the static payload against gravity, while lightweight electromechanical actuators …

Computational Studies On The Major Antioxidant Enzymes Of Wuchereria Bancrofti Towards The Development Of Anti Filarial Leads, Sureshan M

Theses and Dissertations

Lymphatic filariasis (LF), or elephantiasis, is a mosquito-borne parasitic disease affecting the lymphatic system, primarily in tropical and subtropical regions. It is the second leading cause of long-term disability and a neglected tropical disease. According to WHO, LF threatens 882 million people in 44 countries, with over 9 billion treatments administered. The disease is caused by three nematodes: Wuchereria bancrofti (90% of cases worldwide, including India), Brugia malayi (10% in Southeast and Eastern Asia), and Brugia timori (found in Timor and nearby islands). Lymphatic filariasis (LF) is an ancient disease that continues to challenge scientists and physicians. Current treatments include …

Hindcasting The Occurrence Time Of Major Earthquakes Using Machine Learning And Time Series Analysis, Rubidha Devi D

Theses and Dissertations

An earthquake is an intense shaking of the ground that typically occurs when tectonic plates move beneath the surface of the Earth. Scientists analyze historical seismic records and geophysical and atmospheric signs to build models estimating the probability of major earthquakes by detecting patterns and anomalies in data such as ground deformation and seismic waves. This study would help in predicting earthquakes to minimize risks of people and buildings. The present study investigates the devastating earthquakes along the Chilean subduction zone in South America, linking non-seismic data to machine learning predictions of Outgoing Longwave Radiation (OLR) and Relative Humidity (RH) …

Fabrication Of Protein-Based Nanomicelle Against Inflamed Synoviocytes In Rheumatoid Arthritis, Madhumithra Thangadurai

Theses and Dissertations

Rheumatoid arthritis (RA) is a chronic autoimmune disease marked by persistent synovial inflammation, progressive cartilage and bone destruction, and systemic complications. 1% of the global population are affected by RA, when their immune system targets synovial tissues, leading to joint pain, swelling, and functional disability. Standard treatments, such as disease-modifying antirheumatic drugs (DMARDs) like methotrexate (MTX), are limited by systemic toxicity and inconsistent patient responses, highlighting the need for improved therapies. This research work explores protein-glycosaminoglycan nanomicelles engineered using Zein with Chondroitin or carboxymethylated Dextran Sulfate as targeted drug delivery vehicles for RA.

MTX was encapsulated within these nanomicelles to …

Perspectives On Northern Gulf Of Alaska Freshwater Pathways, Wind, And Linkages To Phytoplankton Biomass, Isaac Reister

Oceanography

The biologically productive northern Gulf of Alaska continental shelf receives freshwater from surrounding watersheds and wind stress from atmospheric pressure systems. A better characterization of the relationship between wind and salinity spatiotemporal variability is important for understanding the fate of freshwater and its ecological importance. In Chapter 2, I analyzed 25 years of northern Gulf of Alaska hydrographic data to reveal mid-shelf and shelf­ break freshwater pathways that impact stratification, currents, and freshwater distribution. Process studies of the Copper River plume’s propagation towards the shelf-break and beyond inform ecological function on the northern Gulf of Alaska shelf and productivity in …