Digital Commons Network^™

A Poly-L-Lysine-Functionalized Electrochemical Immunosensor Enables Highly Sensitive Detection Of Tumor Necrosis Factor Receptor-Associated Protein 1, Berfi̇n Vural, Mustafa Kemal Sezgi̇ntürk

Turkish Journal of Chemistry

Tumor necrosis factor receptor-associated protein 1 (TRAP-1), a member of the mitochondrial heat shock protein family (HSP90), is essential for protein homeostasis, stress response, and cell cycle. TRAP-1 not only optimizes cellular energy production but also prevents cell death, thereby supporting the survival and proliferation of tumor cells. In addition to cancer, TRAP-1 has been associated with Parkinson’s disease, certain autoimmune disorders, and abnormalities in the kidney and urinary tract. In this study, a unique and useful indium tin oxide-polyethylene terephthalate (ITO–PET)-based electrochemical biosensor is described for detecting the biomarker TRAP-1. The ITO–PET electrode, selected as the working electrode, is …

Accounting Response To Inflation And Its Implication On Economic Development In Nigeria, Jimoh Ojo Ihiovi

Bullion

This study examines the relationship among inflation, accounting responses, investment, regulatory compliance and economic development in Nigeria. It uses secondary data from official macroeconomic sources and selected corporate reports and applies descriptive statistics, correlation analysis and Ordinary Least Squares regression. The reported results show a negative association between inflation and GDP per capita, while accounting response, investment and regulatory compliance have positive associations with economic development. The study recommends stronger inflation-sensitive disclosures, improved enforcement and professional capacity, while recognising that IAS 29 applies only where its hyperinflation criteria are met.

Non-Oil Exports And International Reserves In Nigeria: A Descriptive Assessment (1981-2023), Oluwabunmi Dada

Bullion

This study examines non-oil exports and international reserve accumulation in Nigeria using annual data from 1981 to 2023. Descriptive statistics, correlation analysis and trend analysis are employed. Services and agricultural exports show modest positive associations with reserves, while manufacturing exports record a strong negative association and mining exports show a negligible relationship. Real GDP, the exchange rate and external debt are positively correlated with reserves. The findings support policies that strengthen export competitiveness, value addition and macroeconomic stability. The reported relationships are descriptive and should not be interpreted as causal effects.

Cash Reserve Ratio As A Monetary Policy Tool In Nigeria: Implications For Banking System Liquidity And Stability, Baba N. Yaaba Phd, Usenobong Akpan Phd

Bullion

In pursuit of price stability, the Central Bank of Nigeria (CBN) deploys a range of monetary policy instruments to regulate liquidity conditions and influence macroeconomic outcomes. Among these, the Cash Reserve Ratio (CRR) has played an increasingly prominent role in recent tightening cycles. While these measures aimed to curb excess liquidity and inflationary pressures, concerns have emerged regarding their implications for bank intermediation and financial stability. This study evaluates the impact of CRR on banking system liquidity and stability in Nigeria using an Autoregressive Distributed Lag (ARDL) model and monthly data from June 2010 to March 2025. The results confirm …

Exploring Elite Athletes’ Perceptions Of The Practice Of Mindfulness For Mental Health And Optimal Performance, Omar A. Sesay

Walden Dissertations and Doctoral Studies

Elite athletes experience physical, cognitive, and emotional demands that affect athletic performance and personal well-being, increasing the risk for anxiety, depression, burnout, attentional difficulties, and maladaptive coping strategies. Mindfulness-based stress reduction (MBSR) has been examined for its effect on attentional control, emotional regulation, cognitive flexibility, and stress resilience, but limited qualitative research has examined how elite athletes experience the practice of mindfulness. The purpose of this generic qualitative study was to explore elite athletes’ perceptions of the practice of mindfulness for mental health and optimal performance. The theoretical framework draws from mindfulness theory and MBSR principles. Semistructured interviews were conducted …

Mapping Measurement To Theory In Policy Evolution: A Case Of Net Metering Policies Of The United States, Graham Ambrose, Myriam Gregoire-Zawilski

Center for Policy Design and Governance

This brief summarizes "Mapping measurement to theory in policy evolution: A case of net metering policies of the United States," co-authored by Graham Ambrose and Myriam Gregoire-Zawilski in Policy Studies Journal.

Learning Challenges And Their Correlation Among Nursing Students Using Artificial Intelligence Bots, Sofia Magdalena Norbe Robles, Francine Isabel M. Adarne, Astrid Jaide Arellano, Charlene Azucenav, Ianne Jasmine A. Bayan, Luis Manuel M. Caudal, Angelica S. De Guzman, Jan Philip Dela Cruz, Gweneth E. Gabon, Adrian Paolo P. Mabahague, Rebeka L. Ricabierta, Andru Nicolas P. Rosal, Jodi Darla S. Taroc, Sheena Margaret B. Valera

International Nursing Research Congress (INRC)

The rise of Artificial Intelligence (AI) has profoundly transformed the digital age, bringing notable implications for nursing education. AI, defined as the simulation of human intelligence in machines (Duggal, 2023), has revolutionized nursing, where students face various challenges related to Knowledge, Skills, and Attitudes (KSA) when using AI bots for academic purposes. This study examines the learning challenges encountered by nursing students in the domains of knowledge, skills, and attitudes (KSA) when using AI bots for academic purposes, particularly in relation to ethical considerations.

A descriptive-correlational research design was employed, using structured questionnaires to analyze the relationship between demographic profiles, …

Immigration Stress And Inequities Driving Diabetes Distress In Hispanic Adults: A Scoping Review, Rachell Nguyen

International Nursing Research Congress (INRC)

Background: Hispanic adults in the United States experience disproportionately high rates of type 2 diabetes mellitus (T2DM) and co-occurring mental health conditions. These disparities are intensified by immigration-related stress, acculturation challenges, and minority stress, all of which contribute to heightened diabetes distress and reduced self-management capacity.

Purpose: This scoping review examined how immigration stressors, acculturation processes, and minority stress influence diabetes distress and mental health outcomes among Hispanic adults with T2DM.

Methods: Using Arksey and O’Malley’s six-step scoping review framework and PRISMA-ScR guidelines, a comprehensive search of PubMed, CINAHL Complete, MEDLINE (OVID), and ScienceDirect identified studies published between 2015 and …

Risk Stratification And Screening For Sleep Apnea In Cardiology Outpatient Setting, Ma Vanessa Simoy Mabazza, Tanya Tanzillo, Paul H. Nguyen, Rubina D. Nguyen

International Nursing Research Congress (INRC)

Background: Obstructive sleep apnea (OSA) is the most prevalent sleep disorder and is strongly associated with cardiovascular disease (CVD), but remains widely underdiagnosed due to inconsistent and non-standardized screening practices in outpatient settings.

Local Problem: Patients with CVD were reported to be diagnosed with OSA following sleep studies at an outpatient cardiology clinic. The need for a consistent, evidence-based approach to risk-stratification and screening was recognized.

Aim: The aim of this project was to increase the sleep apnea risk stratification rate among new adult cardiology patients from 53% to at least 85% over a 16-week implementation period by incorporating the …

Bridging Theory And Innovation: Cultivating Nursing Scholars Through Research, Ai And Mentorship, Charlene Whitaker-Brown, Judy Cornelius

International Nursing Research Congress (INRC)

As a newly R1 Carnegie Classification institution, in the Southeastern part of the United States, there is renewed emphasis on expanding research opportunities for undergraduate and graduate students. In response, the Research Explorer Program commencing in Winter 2025 is being launched as a pilot initiative to enhance student research engagement within the School of Nursing.

This program introduces a cohort of 10 undergraduate nursing students to the fundamentals of nursing research through mentorship with graduate nursing students. Grounded in the belief that early exposure to research strengthens clinical reasoning, evidence-based practice, and leadership, the initiative will provide undergraduates with hands-on …

Fmea-Based Risk Assessment And Improvements For Vascular Access Education In Hemodialysis, Nai-Hua Hsiao

International Nursing Research Congress (INRC)

This study evaluates and improves the patient education and care process before and after arteriovenous fistula surgery in hemodialysis patients. Inadequate implementation of this process may lead to multiple clinical risks. Currently, Southern X Hospital lacks a standardized patient education protocol, resulting in duplicated, omitted, or inconsistent content. These deficiencies negatively affect patients' comprehension and adherence, potentially leading to resource waste and reduced dialysis quality. To address these issues, this study applies Failure Mode and Effects Analysis (FMEA) to systematically identify potential failure modes within the education and care continuum. The CRITIC (Criteria Importance Through Intercriteria Correlation) method is used …

Nursing Students’ Experiences With Immersive Pediatric Emergency Learning, Hsiang-Yun Lan, Jen-Jiuan Liaw, Yu-Lun Tsai, Chen-Xi Lin, Chiao-Hsuan Lin, Pao-Ju Chen

International Nursing Research Congress (INRC)

Background: Pediatric emergencies are characterized by their unpredictability and complexity, yet opportunities for direct clinical exposure remain limited for undergraduate nursing students. This gap poses challenges to the development of clinical judgment and rapid response competencies.

Purpose: This study aimed to examine how the integration of immersive simulation and inquiry-based learning enhances nursing students’ learning outcomes and shapes their experiences in managing pediatric emergency scenarios, using a simulated child seizure event as the core exemplar.

Methods: A qualitative phenomenological approach was adopted. Purposive sampling was used to recruit 12 nursing students who had completed the instructional intervention. Data were collected …

Rewilding Health: A Global Nursing Framework For Nature-Based Interventions And Planetary Well-Being, Amber Lea Vermeesch, Mary Rockwood Lane, Erica Timko Olson

International Nursing Research Congress (INRC)

Purpose: Rewilding—defined as restoring natural ecosystems and reconnecting humans to nature—offers a scalable, evidence-informed strategy to advance global health goals identified by the World Health Organization and United Nations Sustainable Development Goal (SDG) 3. This project examines how nurses can operationalize rewilding and nature-based interventions (NBIs) as ethical, clinical, and policy actions supporting universal health coverage, mental health promotion, non-communicable disease prevention, and global well-being.

Background: Growing evidence demonstrates that exposure to nature reduces stress, improves immune function, decreases depression and anxiety, enhances cancer survivorship outcomes, and promotes social connectedness. Aligning with Watson’s Unitary Caring Science and Chinn’s Emancipatory Nursing, …

Mindful Parenting And Toddlers' Food Responsiveness: The Role Of Controlling Feeding Practices, Qingyu Jiang, Holly Wilhite, Natalie A. Williams, Dipti A. Dev, Caron A. C. Clark, Pearl Avari, Sarah B. Ladd

Journal of Extension

Controlling feeding practices may negatively impact children's eating behaviors. Mindful parenting may offer a promising way to reduce the use of these practices. This study examined the mediating role of pressuring children to eat and using food as a reward in the association between mindful parenting and toddlers' food responsiveness. Results indicated that higher levels of mindful parenting were associated with lower pressuring to eat, which was related to lower food responsiveness in toddlers. The results may inform Extension professionals providing mindfulness strategies for mothers of young children to improve feeding practices, ultimately reducing children's unhealthful eating behaviors.

The Role Of Green Competence In Enhancing Green Performance Among Healthcare Workers In Indonesian Community Health Centers, Dewi Susanna, Tris Eryando, Dwi Agustina, Artha Prabawa, Rabiatul Adawiah, Lusianah Lusianah, Ratna Sari Dewi

Media Kesehatan Masyarakat Indonesia

Climate change poses increasing risks to population health and healthcare systems worldwide. Primary healthcare facilities, partic-ularly community health centers, play a critical role in climate change mitigation and adaptation through environmentally sustainable practices. This study aimed to assess the level of green competency of Puskesmas staff and analyze relationship in the green behavior. A cross-sectional study was conducted among 102 personnel at the Community Health Center in East Jakarta, Indonesia, using a total sampling approach. Green competence was measured across five dimensions (knowledge, skills, abilities, attitudes, awareness) involving a structured questionnaire. Data were analyzed using descriptively and inferentially using chi-square …

Remarkable Seizure Reduction With Trofinetide Treatment In An Adult With Rett Syndrome: A Case Report, Semihan Adegbite, Pooneh Memar Ardestani, Maromi Nei

Department of Neurology Faculty Papers

No abstract provided.

Improved Foraminal Expansion And Pain Scores Following Placement Of Novel Expandable Interlaminar Stabilization Device For Lumbar Spinal Stenosis, Robert P. Norton, Ian Koch, Kendra Primavera, Roy Y. Miloh, Alex R. Vaccaro, Mitchell K. Ng

Department of Orthopaedic Surgery Faculty Papers

STUDY DESIGN: Retrospective cohort study.

OBJECTIVE: To evaluate radiographic durability and clinical outcomes following placement of a novel expandable interlaminar stabilization device for single-level lumbar spinal stenosis. Specifically, we aimed to: 1) quantify immediate postoperative posterior column distraction; 2) determine whether foraminal expansion is improved postoperatively without radiographic subsidence; and (3) assess potential improvements in patient-reported pain/clinical outcomes.

METHODS: A retrospective review was performed of adult patients undergoing single-level decompression supplemented by an interlaminar device for symptomatic lumbar spinal stenosis by a single surgeon from 2024 to 2025. Radiographic parameters included anterior, middle, and posterior disc height, foraminal height, and …

Parents’ Perceptions Of Their Children With Disabilities’ Mental Health During The Rapid Transition To Online Learning At The Time Of The Covid-19 Pandemic, Arnell Rorie Footman

Walden Dissertations and Doctoral Studies

The COVID-19 pandemic prompted an abrupt shift to online learning, raising significant concerns about the mental health of children with disabilities. Existing research highlights increased rates of anxiety, depression, and social isolation during due to the disruptions in structured routines and in-person support systems. This generic qualitative study, guided by Bronfenbrenner’s EST was conducted to explore parents’ perceptions of the mental health challenges experienced by their students with disabilities during the rapid transition to online learning at the time of COVID-19 pandemic. Data was obtained through semi-structured interviews in which parents voiced their perceptions and experiences concerning their children’s mental …

Evaluation Of A Multiantigen Mrna Vaccine Against Eehv1a In Asian Elephants, Lauren Farris, Jessica Watts, Jeroen Pollet, Christine Molter, Sarah Cannizzo, Michael Wenninger, Jessica Heinz, Rebecca Eddy, Jessica Emerson, Dewey Maddox, Paul D Ling

Faculty, Staff and Students Publications

Elephant endotheliotropic herpesvirus (EEHV) is endemic in Asian elephants and can cause fatal hemorrhagic disease (HD) in juveniles, with calves aged 1-8 years being most vulnerable, particularly following the decline of maternal antibodies. Current supportive treatments, which commonly include fluids, plasma infusions, and human anti-herpesvirus drugs, are not consistently effective, highlighting the urgent need for preventative strategies. To address this challenge, we generated an EEHV1A multi-antigen mRNA vaccine targeting four conserved herpesvirus entry proteins (gB, gH, gL, and gO), which elicited robust humoral and cellular immune responses in mice without adverse effects. Based on these preclinical findings, a vaccine trial …

First Evidence Of Clinical Protection From An Eehv1a Mrna Vaccine In Naturally Infected Juvenile Elephants, Michael Wenninger, Lauren Farris, Jessica Heinz, Rongsheng Peng, Gary S Hayward, Jessica Watts, Jeroen Pollet, Jenny Nollman, Paul D Ling

Faculty, Staff and Students Publications

Juvenile Asian elephants who have lost maternal antibodies are particularly susceptible to fatal hemorrhagic disease caused by primary infection with elephant endotheliotropic herpesvirus 1A (EEHV1A). To address this vulnerability, a multi-antigen EEHV1A mRNA vaccine has been administered to EEHV1A seronegative calves at four institutions. However, the extent to which this vaccine confers protective immunity remains an open question. In November 2023, two juvenile male calves (aged 6 and 7 years) were transferred from Dublin Zoo to the Cincinnati Zoo and Botanical Garden and confirmed to be seronegative for EEHV1A. Both calves received an experimental EEHV1A mRNA vaccine in October 2024, …

Addressing Knowledge And Data Gaps That Limit Pesticide Risk Assessment For Managed Solitary Bees Used For Alfalfa Pollination, Kimberly J. Hageman

Funded Research Records

No abstract provided.

Using Posters To Increase Vegan Entrées Chosen At Classics In Wmu’S Student Dining Center, Sarah Schneider

Honors Theses

The following experiment tested the use of specifically designed posters to see the effect on eating habits of those who ate entrées from WMU’s food counter called Classics in the Student Dining Center. The independent variable was a poster with humorous and factual elements displayed at the point of choice in the dining center. The primary dependent variable was the percentage of vegan entrees chosen out of the total number of vegan and meat entrees served. The secondary dependent variables were the number of vegan entrees prepped and served, and the percentage of each entree that was served out of …

Cover And Contents

Turkish Journal of Chemistry

No abstract provided.

Biological And In Silico Evaluation Of Amino Sulfonic Acids With Antioxidant And Cytoprotective Activities, Amir Rahim Khallawi, Kasim Mohammed Hello

Muthanna Medical Journal

Background: Amino-sulfonic derivatives are recognized for their diverse biological roles, particularly in modulating physiological environments and cellular protection. Understanding their interaction with enzyme systems like carbonic anhydrase (CA) is crucial for developing therapeutic strategies against oxidative stress and metabolic imbalances.
Objective: This study aims to systematically evaluate the antioxidant, cytoprotective, and pH-modulating activities of four amino-sulfonic derivatives—taurine (TA), pyridine-3-sulfonic acid (P-3-S), sulfamic acid (SA), and hydroxylamine-O-sulfonic acid (HASA)—using CA-containing systems derived from healthy and leukemia samples.
Materials and methods: Antioxidant capacity was determined through DPPH radical and H₂O₂ scavenging assays. Cytoprotection was assessed via lactate dehydrogenase (LDH) …

Molecular Pathogenesis And Genomic Profiling Of Fusobacterium Nucleatum: A Review Of Virulence Determinants & Antimicrobial Resistance Mechanisms In Dental And Systemic Infections, Mawahb Hatem Mones, Thariat Abdualrahman Al-Joubori, Ibrahim Faisal Ibrahim

Muthanna Medical Journal

Fusobacterium nucleatum is one of the key bacteria in the oral microbiota, which plays a key role in the structural integrity of dental plaque, an anaerobic bacterium. Emerging clinical evidence has increasingly linked this opportunistic pathogen to severe systemic pathologies, notably colorectal cancer and adverse pregnancy outcomes. This review synthesizes current genomic and molecular insights to elucidate the complex mechanisms driving fusobacterial virulence and antimicrobial resistance (AMR). We critically discuss the roles of key adhesins, such as FadA and Fap2, in modulating host cell signaling and facilitating immune evasion. Furthermore, we determine the genomic architecture involved in the transfer …

Emerging Aiot-Based Approaches For Early Detection Of Cardiac Diseases: A Review, Balqees Talal Hasan, Zaid J. Al-Araji, Zainab Al-Badrany, Sarah Kanaan Hamzah, Abdulmajeed Sulaiman

Mesopotamian Journal of Artificial Intelligence in Healthcare

Cardiovascular disease continues to pose a serious global health burden, emphasizing the need for smart, ongoing, and clinically trustworthy systems for early detection of this condition. The convergence of IoT-enabled sensing technologies with AI has led to the rise of an innovative paradigm known as AIoT, integrating technologies such as machine learning, deep learning, edge and fog computing, and cloud-based analytics with the aim of real-time cardiac monitoring and diagnostic decision support. Despite rapid expansion, current literature appears disparate in its coverage of sensing modalities, learning algorithms, system architectures, data sets, evaluation criteria, and clinical applications. To remedy this, a …

Inter-Axle Torque Coordination And Upshift Optimization Of Porsche Taycan’S Awd Propulsion System Via Multi-Domain Simulation, Darrell Robinette, Peter Pollock, Dillon Babcock, Joshua Orlando

Michigan Tech Publications

This paper presents the development of a multi-domain simulation for the Porsche Taycan’s all-wheel-drive (AWD) electric propulsion system to investigate the impact of the rear drive unit’s two-speed transmission on performance and drive quality during maximum acceleration. This study was undertaken independent of the vehicle and propulsion system OEM. A lumped-parameter model of the front and rear electric drive units (EDU) and the high-voltage battery was developed and calibrated against the published data for key benchmarks, including 0–100 kph acceleration times and peak longitudinal acceleration. The mechanical shifting mechanism was reverse-engineered to simulate high-performance shift trajectories. To manage the transition, …

Boss Up/Bake Bread, Jess Flanigan

Jepson School of Leadership Studies articles, book chapters and other publications

Taylor Swift’s “Wi$h Li$t” describes people who “want it all.” There, she declares that, in contrast to those who want it all, she dreams about living a quiet life with a driveway and a basketball hoop. This chapter argues that dreaming about a driveway with a basketball hoop while staying married to the hustle is still a form of wanting it all. Like Swift, and me, many other women today enjoy a degree of autonomy and material abundance that our grandmothers could only dream about. We’re free to boss up or settle down. But still, we have to make trade-offs. …

Anterior Neck Induration As The Initial Sign Of Metastatic Gastrointestinal Adenocarcinoma, Fahad Siddiqui, Jay Nguyen, Victoria Dukharan, Rajiv Nathoo

GME Publications

No abstract provided.

Problematika Learning Loss Pada Kompetensi Pelayanan Dan Kesiapan Kerja Lulusan Smk Perhotelan: Studi Kasus Di Smkn 1 Jonggat, Heny Afrianti, Supiati Warni, Zulkarnain Zulkarnain, Endang Supiyatun, Irya Isnawati, Basilius Redan Werang

Journal of Innovation and Teacher Professionalism

Learning loss in vocational education is associated not only with reduced mastery of subject matter but also with limited practical experience required to develop occupational skills. This study aimed to analyze the forms of learning loss in hospitality education, learning conditions associated with competency gaps, and their implications for practical service skills at SMKN 1 Jonggat. A qualitative case study design was employed. Data were collected through semi-structured interviews, observations, and documentation involving five purposively selected informants comprising teachers, graduates, and industry representatives. The data were analyzed thematically through coding, category development, theme generation, and interpretation. The findings indicate that …