Digital Commons Network^™

Mathematical Analysis Of Toxicants And Diseases Impact On A Prey-Predator System With Control Interventions, Nuru Yazidi Juma, Thadei Damas Sagamiko, James Philbert Mpele

Tanzania Journal of Science

This study developed a generic prey-predator mathematical model incorporating logistic growth for prey and a Holling Type I functional response for predator consumption. Prey-predator interactions form the foundation of ecological balance, but in recent decades these systems have been increasingly threatened by toxicants and infectious diseases. The combined effect of these challenges can lead to severe population declines, biodiversity loss, and ecosystem instability, making their study important for conservation and environmental management. The model includes the effects of diseases and toxicants on prey and toxicants only on predators, and explores optimal control strategies to mitigate these threats. Without considering time …

Design Of High-Performance Synchronous Reluctance Motor For Hybrid Electric Vehicle Application, Fred Loita, Jackson Justo

Tanzania Journal of Science

This paper presents the simulation-based design of a synchronous reluctance motor (SynRM) coupled electromechanical system suitable for the hybrid electric vehicle. The study considers SynRM with a 75kW power rating with the capability to produce up to 125kW maximum power for the electric vehicle. The focus is mainly on rotor and stator design; the angles of the flux-barrier ends are considered to reduce the torque ripple due to the slot harmonics. Reluctance machines are indeed competitive for applications requiring high efficiency at low cost. However, it is a challenging task to find design solutions that ensure structural integrity of the …

Rainwater Harvesting For Domestic Use In Suburb Areas Of Dar Es Salaam, Tanzania: A Case Study Of Wazo Hill, Scholastica S. Ishengoma, Mahir Mohammed Said, Neema O. Msuya

Tanzania Journal of Science

Despite the increasing reliance of rainwater harvesting in semi-urban areas, there is a lack of comprehensive localized data on the safety of harvested rainwater, particularly in areas such as Wazo Hill where communities predominantly depend on it. This study evaluates the quality of harvested rooftop rainwater intended for human consumption and assesses its compliance with the World health Organization (WHO) and Draft East Africa Standards (DEAS) for drinking water. Rainwater samples were collected from various catchment surfaces and storage systems located in Wazo Hill, Tanzania. A stratified random sampling technique was employed to select the households equipped with rainwater harvesting …

Assessment Of Bacteriological Quality And Physico-Chemical Parameters Of Domestic Water Sources In Relation To Human Health Risk In Kigamboni, Tanzania, Joseph A. Mwakosya

Tanzania Journal of Science

Data on bacteriological quality and physico-chemical parameters is crucial for protection and sustainable utilization of water resources. This study determined bacteriological quality and physico-chemical parameters of well and tap water sourcesin relation to human health risk in Kigamboni, Tanzania. Thirty water samples were collected randomly and analyzed using SPSS software. The mean values for well water samples of pH, electrical conductivity (EC), total dissolved solids (TDS), turbidity, Chloride, Sulphate, Nitrate, Phosphate, and Calcium Carbonate were 7.2, 960.27 mg/L, 528.13 mg/L, 1.52 NTU, 288.00 mg/L, 30.13 mg/L, 0.05 mg/L, 0.08 mg/L, and 160.07 mg/L, respectively. The mean values for tap water …

Comparative Study On The Application Of Gra, Psi And Hybrid Psi-Gra Techniques For Optimising Turning Parameters In Multi-Criteria Problems, Mussa Iddi Mgwatu

Tanzania Journal of Science

The optimum turning parameters help to justify the investment in machine tools for manufacturing industries. However, solving optimisation models to achieve optimum turning parameters in multi-criteria environment is complex leading to the application of multi-criteria decision-making techniques. This paper compares three multi-criteria decision-making techniques in determining optimum turning process parameters namely spindle speed, feed rate and depth of cut. The performance criteria are material removal rate, consumed electrical energy and tool wear rate. Example data for turning process were obtained from other studies while the analyses for multi-criteria decision-making were performed using grey relational analysis (GRA), preference selection index (PSI) …

Heavy Metal Contamination And Health Risks In Katoro's Artisanal Gold Mining Soils, Tanzania, Innocent J. Lugendo, Venance Mwesiga

Tanzania Journal of Science

This study assessed heavy metal contamination in surface soils from artisanal gold mining areas in Katoro, Tanzania, evaluating ecological and human health risks. Thirty-six soil samples were systematically collected from three mining villages (Bingwa, Isenye, and CCM) at varying distances ranging from 30 to 90 m from active mining pits alongside twelve control samples from a non-mining area for comparison purposes. Concentrations of Cr, Cu, Ni, Zn, Pb, and As in soil samples were analyzed using energy-dispersive X-ray fluorescence spectrometry (EDXRF). Results revealed severe contamination, with Cr (117–1255 mg/kg), Cu (81–104 mg/kg), and Ni (89–271 mg/kg) exceeding permissible limits. The …

Crude Extracts Of Seaweeds (Ulva Lactuca And Eucheuma Spinosum) As Biostimulants For Enhancing Sweet Pepper Production, Charles Olambo Joseph, Seif Amour M

Tanzania Journal of Science

Sweet pepper is the world’s second most important vegetable after tomato, making its production vital for economic growth and supporting livelihoods. However, growing concerns about environmental protection and sustainability make the search for eco‑friendly alternatives to synthetic fertilizers inevitable. Seaweed extracts are rich in bioactive compounds that can stimulate key plant growth and defense pathways making them effective biofertilizer. A Randomized Complete Block Design was laid out to evaluate the potential of seaweed extract (U. lactuca and E. spinosum) in promoting the growth and productivity of sweet pepper(Capsicum annuum L.). Seaweed was applied in both liquid and …

Spatio-Temporal Dynamics Of The Onset And Cessation Of Ond Rainy Season Across Bimodal Regions Of Tanzania, Rajabu J. Mangara, Paul Ts Limbu

Tanzania Journal of Science

This study investigates the temporal variability of the onset, cessation, and duration of the October-November-December (OND) rainy season in the bimodal rainfall region of Tanzania. Utilizing daily precipitation data from the Multi-Source Weighted-Ensemble Precipitation dataset for the period 2014–2023, the study employs the Accumulated Daily Index method to determine the onset and cessation of rains, with the seasonal duration computed as the difference between these dates. Variability in onset, cessation, and season length was quantified using the Coefficient of Variation. The findings highlight significant spatial variability in onset, with early rains in northwestern areas (e.g., Bukoba) and coastal zones, commencing …

Comparative Evaluation Of Dicyclohexylamine And N-Methyldiethanolamine As Corrosion Inhibitors For Top Of Line Corrosion On Api X80 Carbon Steel In Saturated Carbon Dioxide Aqueous Solutions, Frida W. Andalu, Abraham K. Temu, Alfred R. Akisanya, Joseph Yn Philip

Tanzania Journal of Science

This work has evaluated the efficiency of selected volatile corrosion inhibitors in mitigation of top of line corrosion in wet gas pipeline at different temperatures. The main challenge of top of line corrosion in carbon dioxide rich environment is the ability of the volatile corrosion inhibitor to effectively mitigate corrosion at adverse conditions. Electrochemical corrosion experiments using potentiodynamic polarization method were conducted at temperatures of 20 ℃, 35 ℃ and 45 °C to evaluate the efficiency of dicyclohexylamine and n-methyldiethanolamine corrosion inhibitors for top of line corrosion inhibition on carbon steel specimens derived from API X80 natural gas pipelines. The …

Energy-Saving Simple Adaptive Recursive Terminal Sliding Mode Control For Industrial Feed Drive Systems, Haryson Johanes Nyobuya

Tanzania Journal of Science

This paper proposes a simple adaptive recursive terminal sliding mode control approach for industrial feed drive systems. The design employs a recursive sliding mode structure that eliminates the reaching phase and ensures finite-time convergence of the tracking error. To mitigate chattering, a second-order nonsingular terminal sliding mode is used and the parameters to compensate for disturbances are obtain in terms of integral form and a proportional terminal term, which enhances disturbance rejection and further guarantees finite-time convergence. The proposed controller significantly reduces the tracking error and saves energy for the feed drive system. Numerical simulations on an industrial feed drive …

Nickel (Ii) Complex Decorated Zinc-Cadmium Sulfide Type-Ii Heterojunction For Enhanced Photocatalytic Hydrogen Production, Miza Kombo, Abdul Muhamed, Suleiman Suleiman, An-Wu Xu

Tanzania Journal of Science

The binary metal sulfide Zn_0.5Cd_0.5S has emerged as a promising photocatalyst for hydrogen (H₂) production via visible-light-driven water splitting. However, its practical application is limited by rapid charge carrier recombination and insufficient stability. In this study, nickel (II)-(3-pyridyl) benzimidazole (NPBIm) complexes were synthesized and employed an ultrasonic-assisted method to decorate the surface of Zn_0.5Cd_0.5S, forming a novel metal-complex semiconductor heterostructure system (Zn_0.5Cd_0.5S/NPBIm). This hybrid system significantly enhances photocatalytic H₂ evolution under visible light irradiation. Experimental findings reveal that the incorporation of NPBIm molecules improves the …

Modeling The Effects Of Screening, Vaccination, Treatment, And Non-Pharmaceutical Controls On Leptospirosis Transmission Dynamics, Janeth Michael, Herieth Rwezaura, Goodluck Mlay, Nyimvua Shaban Mbare

Tanzania Journal of Science

Leptospirosis is the world’s most common zoonotic disease and remains a significant public health challenge, particularly in regions with poor sanitation and high exposure risks. This study aims to evaluate the effectiveness of combined interventions: screening, vaccination, treatment, and non-pharmaceutical controls in reducing leptospirosis transmission in human and domestic animal populations. The study develops and analyzes a deterministic compartmental model with eleven compartments representing human, domestic animal, and bacterial populations. Stability analysis reveals that the Disease-Free Equilibrium (DEF) is globally asymptotically stable when the effective reproduction number is less than a unit ( < 1), ensuring disease eradication under these conditions, whereas the Endemic Equilibrium Point (EEP) remains stable when > 1. The study employs the normalized forward …

Dynamic Lqr Control For Improved Dc Link Voltage Stability In Grid-Integrated Solar Pv System, Peter Makolo, Mwanajuma Gora, Francis Mwasilu, Jackson Justo

Tanzania Journal of Science

The integration of photovoltaic (PV) systems into power grids poses a significant challenge to voltage stability, especially at the DC link. Fluctuations in solar irradiance directly cause power variations and instability in this critical interface. If not properly controlled, this variability can lead to inefficiencies, equipment damage, and widespread grid disturbances. To address the abovementioned challenge, this paper proposes a dynamic converter control strategy designed to enhance DC link voltage stability in grid-integrated solar PV system. The core of the proposed control system is based on a Linear Quadratic Regulator (LQR) mechanism, implemented within a two-stage, PV grid connected system …

Prevalence And Molecular Characterization Of Non-Typhoidal Salmonella In Poultry Of Dar Es Salaam, Tanzania, Tumwi T. Salah, Paulo S. Joseph, Bishop I. Magidanga, Richard S. Mwakapuja, Victor A. Makene

Tanzania Journal of Science

Poultry is one of the common source of non-typhoidal Salmonella and poultry products are the major sources of human and animal infections with the Salmonella. A cross-sectional study was conducted to determine the prevalence of non-typhoidal Salmonella in live commercial and backyard chickens from retail markets and farms in Dar es Salaam city, Tanzania. The study was conducted in four districts; Ubungo, Kinondoni, Temeke and Ilala. A total of 400 chickens (120 broilers, 120 layers and 160 backyard chickens) were tested for Salmonella. Salmonella isolation and identification was carried out using bacteriological standard methods and polymerase chain reaction (PCR) …

Morphological And Biochemical Characterization Of Endophytic Bacteria From Selected Medicinal Plants Found At The University Of Dar Es Salaam, Tanzania, Ibrahim Juma

Tanzania Journal of Science

Endophytic bacteria are capable of colonising internal tissues of medicinal plants, and producing secondary metabolites (biochemical compounds) of beneficial importance like the ones produced by their host plants. Though Tanzania harbours a wide species of medicinal plants with endophytic bacteria capable of producing such important bioactive substances, research on these bacteria remains scant, which limit their biotechnological applications. This work was undertaken to isolate and document endophytic bacteria from tropical almond, local avocado, banana and blue snake weed plants found at the University of Dar es Salaam, main campus. The study characterised the isolated endophytes based on morphological descriptors and …

Perioperative Benefits Of Dexmedetomidine As An Antiarrhythmic Agent In Noncardiac Surgical Patients: A Case Report, Sara Jaison, Kusuma Halemani

Sultan Qaboos University Medical Journal

Dexmedetomidine (DEX), a selective α2-adrenergic receptor agonist, has gained recognition for its sedative, anxiolytic, and sympatholytic properties, making it a valuable perioperative agent. This report describes the anaesthetic management of an elderly 75-year-old male patient with septic shock, multi-organ dysfunction, delirium and significant ventricular arrhythmias who presented in 2025 to a tertiary care teaching hospital in Oman and was scheduled for an emergency below-knee amputation. DEX was utilised for intraoperative sedation and its antiarrhythmic effects. Traditional sedatives often exacerbate delirium or pose cardiorespiratory risks; however, DEX provides effective sedation while preserving respiratory function and promoting haemodynamic stability. Notably, its …

Complexity Measures For Self-Similar And Chemical Graphs Using Entropies And Generalized Fractal Dimensions, J. Bhuvaneswari, D. Easwaramoorthy

Baghdad Science Journal

Nonlinear analysis finds numerous applications in understanding the intricate characteristics of generalized Sierpinski graphs or chemical graphs. It aids in discerning the fractal patterns inherent in self-similar structures, deciphering the dynamic interactions within chemical bonds, and assessing the complexity of molecular arrangements. Furthermore, it plays a crucial role in unraveling the emergent behaviors of complex systems, offering insights applicable to diverse fields such as materials science, chemistry, biology, network theory, and beyond. In this paper, the complexity of generalized Sierpinski graphs and chemical graphs is analyzed using fractal-based nonlinear measures computed iteratively. Nonlinear measures assess intricate relationships within graphs by …

On The Statistical Variation Of Γ-Covers Controlled By The Class Of Weight Functions, Parthiba Das, Jalal Hatem Hussein Al-Bayati, Prasenjit Bal

Baghdad Science Journal

In this study, the notion of the star operator and the class of weight functions defined on the entire natural number set ℕ have been used to develop a version of the statistical cover of a topological space. In this version of statistical γ-cover, the pace of statistical convergence is mostly controlled by the selected weight function. A map g defined as g:ℕ→[0,∞)such that lim_n→∞g(n)=∞ and lim_n→∞⁄ng(n)≠0is called a weight function. Relationships between several γ …

Lung Cancer Classification With High Accuracy Based On Enhanced K- Nearest Neighbor Algorithm, Ahmed Subhi Abdalkafor, Ali Azawii Abdul Lateef

Baghdad Science Journal

Lung diseases have newly increased, with lung cancer being the most serious, as a result of the widespread use of electronic cigarettes and the high demand for them among youth. Misdiagnosis of this disease has resulted in a high death rate around the world, which further complicates matters. So the researchers have tended to concentrate on and study this illness. After extracting the crucial characteristics for this cancer's classification, several studies implemented multiple artificial intelligence algorithms with different techniques, nonetheless, the primary difference between those studies persisted in the classification accuracy. In this paper, after selecting the methods of pre-processing …

Strategies For Obtaining High-Performance Li-Ion Solid-State Electrolytes For Solid-State Batteries, Yi-Cheng Deng, Zi-Chang You, Geng-Zhong Lin, Guo Tang, Jing-Hua Wu, Zhi-Min Zhou, Xiang-Chun Zhuang, Li-Xuan Yang, Zhen-Jie Zhang, Zhao-Yin Wen, Xia-Yin Yao, Chang-Hong Wang, Qian Zhou, Guang-Lei Cui, Ping He, Hui Li, Xin-Ping Ai

Journal of Electrochemistry

With the widespread adoption of lithium-ion batteries (LIBs), safety concerns associated with flammable organic electrolytes have become increasingly critical. Solid-state lithium batteries (SSLBs), with enhanced safety and higher energy density potential, are regarded as a promising next-generation energy storage technology. However, the practical application of solid-state electrolytes (SSEs) remains hindered by several challenges, including low Li⁺ ion conductivity, poor interfacial compatibility with electrodes, unfavorable mechanical properties and difficulties in scalable manufacturing. This review systematically examines recent progress in SSEs, including inorganic types (oxides, sulfides, halides), organic types (polymers, plastic crystals, poly(ionic liquids) (PILs)), and the emerging class of soft …

High-Voltage Solid-State Lithium Batteries: A Review Of Electrolyte Design, Interface Engineering, And Future Perspectives, Cheng Yang, Zi-Xin Liang, Ming-Yun Zhang, Ming-Zhe Chen, Kai Zhang, Li-Min Zhou

Journal of Electrochemistry

Solid-state lithium batteries have become a research hotspot in the field of large-scale energy storage due to their excellent safety performance. The development of high-voltage positive electrode materials matched with lithium metal anode have advanced the energy density of solid-state lithium batteries close to or even exceeding that of lithium batteries based on a liquid electrolyte, which is expected to be commercialized in the future. However, in high voltage conditions (> 4.3 V), the decomposition of electrolyte components, structural degradation, and interface side reactions significantly reduce battery performance and hinder its further development. This review summarizes the latest research progress …

Enhancing Hand Hygiene Compliance Among Icu And Nicu Visitor Families: The Impact Of Advanced Nursing Roles, The Barriers And Challenges: A Review, Siti Azuna Abu Bakar, Khin Thandar Aung, Sahrom Abdullah

Individual Open Access Articles

Proper hand hygiene is crucial for preventing,, infections in intensive care units (ICUs) and neonatal intensive care units (NICUs). Despite the awareness among healthcare personnel and visitors of its importance, compliance with regulations is often inadequate. Advanced nurse educators and infection control professionals can significantly improve these habits. This review investigates whether advanced nursing positions improve hand hygiene among ICU and NICU families, as well as visitors, focusing on enhancing hand hygiene programs, identifying effective solutions, recognising practice shortcomings, and providing recommendations. The methodology involved a search of databases, including PubMed, CINAHL, Scopus, and Google Scholar, using relevant keywords related …

Optimization Strategies For Nucleic Acid Aptamer Sequences And Its Application In The Detection Of Food Hazards, Yuan Jie, Yao Jun, Zhang Sicheng, Qin Yadi

Food and Machinery

Foodborne diseases have become a prominent problem in the field of food safety. Rapid and accurate detection of food hazards is a key step in controlling foodborne diseases. As a novel biological recognition molecule, nucleic acid aptamers have become a research hotspot for constructing rapid and sensitive biosensors for the detection of food hazards. However, the affinity and selectivity of aptamers screened by Systematic Evolution of Ligands by Exponential Enrichment (SELEX) still need improvement to fully meet the requirements of analytical detection. This paper analyzes the intrinsic factors affecting aptamer performance, focuses on optimization strategies for nucleic acid aptamers, introduces …

A New Scheme For Simple Asymmetric Bivariate Copulas And Applications, Rachid Bentoumi, Farid El Ktaibi, Christophe Chesneau

All Works

Bivariate copulas play a central role in modeling the dependence structure between two random variables and serve as a fundamental tool in various applied fields. In this article, we develop a new theoretical framework aimed at constructing simple asymmetric bivariate copulas of the form C(u, v) = uv [ϕ(v) + u(1 − ϕ(v))^], (u, v) ∈ [0, 1]². This framework relies on a tuning univariate function to achieve the desired asymmetry. We study this pioneering scheme, emphasizing its theoretical foundations, and illustrating it with several examples. More precisely, we establish important properties of the proposed copulas …

Meta Transfer Learning For Brain Tumor Segmentation Using Nnunet In Meningioma And Metastasis Cases, Mehnaz Tabassum, Antonio Di Ieva, Sidong Liu

Staff Scholarship - Australia & Dubai

In recent years, numerous algorithms have emerged for the segmentation of brain tumors, driven by advancements in deep learning techniques, where the objective is to identify and delineate various tumor sub-regions. While deep learning models like nnUNet have shown promising results in glioma segmentation, their effectiveness in segmenting other brain tumor subtypes, such as meningiomas and metastases, remains uncertain, especially when the available dataset lacks representative examples. To address this challenge, we propose a meta-transfer learning approach, which involves fine-tuning the nnUNet model on datasets containing meningiomas and metastases while leveraging the knowledge acquired from glioma segmentation. This approach aims …

Development Trends And Priority Research Fields Of Electrochemical Discipline In The 15th Five Year Plan Period, Lin Zhuang, Wen-Bin Cai, Heng-Xing Ji, Qing Li, Gong-Wei Wang, Sen Xin, Qing Zhao, Fang-Yi Cheng, Yu-Guo Guo, Lan-Qun Mao, Yang Tian, Fei Wu, Li-Min Zhang, Yan Xiang, Jin-Song Hu, Rui Cao, Li Xiao, Hua-Bing Tao, Wei Xing, Dong-Ping Zhan, Hong-Gang Liao, Mei-Ling Xiao, Bin Ren, Zhang-Quan Peng, Rui Wen, Xiang Wang, Yue-Feng Song, Hou-Fu Lv, Bao-Yu Xia, Guo-Xiong Wang, Jun Cheng, Zhi-Pan Liu, Min Zhou, Bing Huang, Cun-Pu Li, Yu-Qin Zou, Shuang-Yin Wang, Hai-Bo Lin, Zi-Dong Wei

Journal of Electrochemistry

In fulfillment of the national science-and-technology development agenda, the Department of Chemical Sciences of the National Natural Science Foundation of China (NSFC) convened the Strategic Symposium on the Fifteenth Five-Year (2026–2030) Development Plan for Electrochemistry held in Xiamen on 29 August, 2025—the culminating year of the Fourteenth Five-Year (2021–2025) Development Plan. More than forty leading experts in the field of electrochemistry participated with spanning nine thematic fronts: Interfacial Electrocatalysis, Interfacial Electrochemistry for Energy Storage, Bioelectrochemistry, Electrochemistry of Hydrogen Energy, Electrochemical Micro-/Nano-Manufacturing, Operando Electrochemical Characterization, Electro-Thermal Coupling Catalysis, Theoretical and Computational Electrochemistry, and Electrochemical Synthesis. The forum assembled China’s foremost electrochemical …

Effect Of Valemetostat On The Pharmacokinetics Of Midazolam And Digoxin: A Phase 1 Drug-Drug Interaction Study In Patients With Non-Hodgkin Lymphoma, Masaya Tachibana, Steven Horwitz, Eric Jacobsen, Francine Foss, Pamela Allen, Pierluigi Porcu, Tatyana Feldman, Jia Ruan, Jonathan Brammer, Jie Wang, Shinichi Inaba, Yuka Iko, Keiko Nakajima, Yasuyuki Kakurai, Noriaki Kitami, Yang Chen, Yvonne Lau

Department of Medicine Faculty Papers

Valemetostat tosylate (valemetostat) is an oral, potent, dual inhibitor of enhancer of zeste homolog (EZH)2/1, under investigation in non-Hodgkin lymphomas (NHLs) and solid tumors. In vitro, it inhibits cytochrome P450 3A (CYP3A) and P-glycoprotein (P-gp) when combined with sensitive CYP3A or P-gp substrates. This drug–drug interaction (DDI) sub-study is part of the phase 1 trial of valemetostat monotherapy (DS3201-A-J101; NCT02732275), assessing the effect of valemetostat on the pharmacokinetics (PK) of sensitive CYP3A and P-gp substrates midazolam and digoxin, respectively, in patients with relapsed or refractory NHL, and its safety and efficacy. Patients received two simultaneous single doses of midazolam and …

What Drives Advanced Practice Nurses To Stay In Rural America? Insights From The 2022 National Survey Of Registered Nurses, Esita Patel, Chris Gillette, Jan Ostermann Phd, Chris Everett, Dawn Caviness, Sarah Garvick

Faculty Publications

Purpose: Recruiting and retaining a robust rural health care workforce is critical to advancing health outcomes in rural communities. Although increasing the rural provider workforce has been a policy focus for decades, rural access continues to worsen. Using a strengths-based approach, we identify factors that influence the decisions of advanced practice registered nurses (APRNs) to leave or stay in their jobs.

Methods: Secondary analysis of data from the 2022 National Sample Survey of Registered Nurses. We describe rates of turnover, retention, intention to leave, and reasons for leaving and staying by job rurality. We compare reasons by rurality using Pearson …

Association Of Stepping-Up To High Dose Inhaled Corticosteroids And Risk Of Future Asthma Exacerbations: Data From The Us, Trung N Tran, Marjan Kerkhof, Tham T Le, Mina Khezrian, Nicole Zubizarreta, Joshua Enxing, Kirsty Rhodes, Jonatan Hedberg, Bill Cook, Tianshi David Wu, Tim W Harrison

Faculty, Staff and Students Publications

Background: Real-world data on the benefit of high-dose inhaled corticosteroid (ICS) post-exacerbation are limited.

Objective: To investigate whether stepping-up to high-dose inhaled corticosteroid (ICS) post-severe exacerbation reduces future asthma exacerbation risk in a real-world setting.

Methods: This was a retrospective cohort study using the Optum® Clinformatics® database (October 2015-December 2023). Patients with asthma, aged ≥12 years, with ≥1 severe exacerbation and ≥2 ICS maintenance prescriptions in the 12-months pre-, and ≥1 ICS maintenance prescription in the 3-months post-exacerbation were included. Primary and secondary endpoints were annualized asthma exacerbation rate (AAER) and time to first subsequent severe exacerbation, respectively. We compared …

Grapes Gone Sour: Navigating Corruption In Cisg Contracts, Ingeborg Schwenzer, Cesar Pereira, Lorenzo Galan

National Law School Business Law Review

No abstract provided.