Digital Commons Network^™

Efficacy Of External Oblique Intercostal Plane Block In Postoperative Analgesia Following Laparoscopic Radical Nephrectomy, Gi̇zem Avci, Yusuf Özgüner, Damla Usalan, Cem Koray Çataroğlu, Habi̇p Yilmaz, Savaş Altinsoy, Jüli̇de Ergi̇l

Turkish Journal of Medical Sciences

Background/aim: The external oblique intercostal plane block (EOIB) is a regional anesthesia technique that may be utilized for the management of postoperative pain following laparoscopic radical nephrectomy. This study aims to evaluate the efficacy of EOIB after laparoscopic radical nephrectomy by comparing 24 h tramadol consumption between groups.

Materials and methods: Initially, 66 patients were enrolled in the study, and after exclusions, 60 were analyzed and divided into two groups: the EOIB group and the control group. Postoperative tramadol consumption, pain scores at rest and during movement, and dermatomal coverage of the block were recorded.

Results: The EOIB group (181.33 …

The Burden Of Knee Pain In The Operating Room: Are Surgical Personnel At Greater Risk?, Ömer Faruk Naldöven, Yavuz Karaman, Başak Si̇nem Sezgi̇n, Şahan Güven, Enejd Vei̇zi̇, İzzet Bi̇ngöl

Turkish Journal of Medical Sciences

Background/aim: This study aimed to determine the prevalence of knee pain among healthcare workers in surgical units and to explore whether the use of knee panels during surgical hand scrubbing is associated with persistent knee pain.

Materials and methods: This single-center cross-sectional study was conducted between October 2023 and March 2025. A total of 400 physicians and nurses working in surgical and nonsurgical departments were included. Participants completed a structured and modified Nordic Musculoskeletal Questionnaire, as well as knee pain assessment tools, including a visual analog scale (VAS) and the Kujala score for anterior knee pain-related symptoms. Occupational exposure among …

Etiologies Of Chronic Cough In Children: A Two-Year Experience From A Tertiary Pediatric Pulmonology Center, Yasi̇n Maruf Ergen, Nagehan Emi̇rali̇oğlu, Ebru Yalçin, Deni̇z Doğru, Uğur Özçeli̇k, Nural Ki̇per

Turkish Journal of Medical Sciences

Background/aim: Chronic cough is a common yet diagnostically challenging symptom in pediatric pulmonology. This study aimed to evaluate the etiologies of chronic cough in children referred to a tertiary center and to analyze the relationship between specific cough characteristics and final diagnoses.

Materials and methods: This retrospective study evaluated patients presenting with chronic cough (duration >4 weeks) at a tertiary pediatric pulmonology center. Demographic data, cough characteristics (wet vs. dry), and diagnostic findings were analyzed.

Results: A total of 62 patients were included. A specific etiology was identified in 95.1% of the patients. Asthma and reactive airway disease were the …

Clinical Features And Outcomes Of Childhood Interstitial Lung Disease: A Tertiary Center Experience, Ayyüce Ünlü, Şule Seli̇n Akyan Soydaş, Sati Özkan Tabakçi, Işil Bi̇lgi̇ç, Meltem Kürtül Çakar, Gamze Akca Di̇nç, Hande Yeti̇şgi̇n, Çelebi̇ Yildirim, Gökçen Di̇lşa Tuğcu, Di̇lber Ademhan Tural, Sanem Eryilmaz Polat, Güzi̇n Ci̇nel

Turkish Journal of Medical Sciences

Background/aim: Childhood interstitial lung diseases (chILD) constitute a rare and clinically complex group of disorders. This study aimed to characterize the clinical, radiological, and genetic features, as well as the outcomes, of chILD in a Turkish cohort classified according to the chILD-EU framework.

Materials and methods: We retrospectively reviewed the medical records of 84 pediatric patients diagnosed with chILD between 2017 and 2024 at a tertiary referral center in Türkiye. Patients were categorized according to the chILD-EU classification. Clinical variables, imaging findings, genetic analyses, pulmonary function test results, and Fan severity scores were systematically assessed. Logistic regression analysis was performed …

Fitness Cost And Biofilm Formation In Fosfomycin-Resistant Clinical Escherichia Coli And Klebsiella Pneumoniae Isolates, Mustafa Ökeer, Sabi̇re Şöhret Aydemi̇r, Bayri Eraç

Turkish Journal of Medical Sciences

Background/aim: Fosfomycin has regained importance owing to its unique mechanism of action and effectiveness against extended-spectrum β-lactamase-producing Gram-negative bacteria. This study aimed to evaluate the biological fitness cost associated with fosfomycin resistance and its impact on biofilm formation in clinical Enterobacteriaceae isolates.

Materials and methods: A total of 78 Escherichia coli and 34 Klebsiella pneumoniae strains isolated from urine samples at Ege University Hospital were analyzed. Fosfomycin minimum inhibitory concentrations (MICs) were determined using the reference agar dilution method. Resistance was induced by exposing two K. pneumoniae strains with a fosfomycin MIC of 4 μg/mL and two E. coli strains …

Nonclassical Philadelphia-Positive Fish Signal Patterns In Cml And Seven Cases With Variant Philadelphia, Sevgi̇ Işik, Oğuz Çi̇li̇ngi̇r, Gülçi̇n Günden, Fi̇li̇z Yavaşoğlu, Hülya Özen, Mert Burak Raşan, Beyhan Durak Aras

Turkish Journal of Medical Sciences

Background/aim: Chronic myeloid leukemia (CML) is characterized by the Philadelphia chromosome (Ph), which occurs as a result of t(9;22). In 5%–10% of CML cases, variant t(9;22)s are observed. Additionally, while t(9;22) is formed, deletions can be observed in chromosomes 9 and 22. These deletions are observed more frequently in variant t(9;22). There is conflicting information in the literature about the prognostic effects of variant t(9;22) and deletions of 9q and 22q. There is also limited information about the frequency and breakpoints of other chromosomes involved in the variant t(9;22). Signal patterns other than the classical signal pattern of FISH analysis …

The Enigmatic Role Of The C-Reactive Protein And Albumin In Behcet’S Disease, Zohreh Jadali

Turkish Journal of Medical Sciences

No abstract provided.

Comment On “Survival Of Patients With 2014 Figo Stage Iiic High‑Grade Serous Ovarian Cancer Treated With Platinum‑Based Adjuvant Chemotherapy”, Abdullah Saad, Syeda Abeeha Hasan, Syeda Aki̇fa Sajid

Turkish Journal of Medical Sciences

No abstract provided.

Creating Healthy Work Environments For New Bsn-Dnp Students Through A Student-Led Mentorship Program, Daniel W. Martin, Christopher H. Connors, Jocelyn Keaton, Todd Tussing

Creating Healthy Work Environments (CHWE)

Background: Graduate students experience unique stressors that affect the decision to complete their programs. These include acclimation to the graduate school environment, coursework, and life balance. Attrition rates between 2006-2015 for DNP (Doctor of Nursing Practice) programs were 13.3-23.8% and 19.2% for BSN-DNP students with most dropping within 2 years. A possible solution to increased attrition could be to help decrease feelings of isolation and support student acclimation. Literature shows mentorship is an effective strategy for graduate nursing programs that results in decreased stress and anxiety, improvement in self-confidence, and improved adjustment to the educational environment. A student led peer …

Beyond "Place Matters": Making Spatial Analysis Accessible With Dashboard-Driven Geography, Stephen Borders

Public Health

This article presents an instructional module that uses Tableau to teach spatial thinking and policy geography through an analysis of Supplemental Nutrition Assistance Program (SNAP) participation. Tableau’s ability to integrate custom spatial files with demographic and health data makes it an accessible platform for introducing geographic inquiry without requiring specialized GIS expertise. The lesson guides instructors through building maps, bullet charts, and scatterplots that highlight gaps between eligibility and enrolment, while connecting food insecurity to health outcomes. By lowering technical barriers, Tableau provides a pedagogical bridge that helps educators foster spatial literacy in diverse classroom contexts.

This article was published …

Lindenwood Writers Receive Pushcart Prize Nominations, Lindenwood University

Archived Lindenwood Press Releases

No abstract provided.

Beyond Rationality: The Role Of Emotions In Communicative Planning, Minji Cho

Urban Studies and Planning Faculty Publications and Presentations

The impact of emotional dynamics has been overlooked within the field of planning. Traditional communicative planning theory, rooted in Habermas’ model of communication, typically propose that emotions should be managed to facilitate rational discussions that lead to logical agreements. Conversely, some research contends that emotions are not illogical or hazardous elements to be restrained during deliberation; instead, they are a topic requiring thorough investigation to create improved public forums. We investigate this tension by analysing facework during a land-use dispute at at the Gongjin Elementary School site in Seoul, South Korea. Our analysis reveals that facework not only impedes the …

Clinical Outcome Of Extremity Arterial Injuries In The Modern Era, Ali̇ Kuşsan, Selçuk Coşkun, Alp Şener, Ferhat İçme, Pinar Köksal Coşkun, Gülhan Kurtoğlu Çeli̇k

Turkish Journal of Medical Sciences

Background/aim: Extremity arterial injuries (EAIs) present a significant clinical challenge due to the risk of limb ischemia, amputation, and mortality. This retrospective cohort study aimed to delineate the clinical course, treatment strategies, and patient outcomes following trauma-induced EAIs, and to identify independent predictors of adverse outcomes.

Materials and methods: Retrospectively analyzed were data from 168 consecutive patients with traumatic EAIs who underwent computed tomography angiography at a tertiary care center between 2019 and 2025. Data extracted from electronic medical records included demographics, injury mechanisms, clinical presentation, laboratory findings, imaging results, treatment modalities (primary repair, grafting, endovascular intervention, conservative management), and …

The Perk Signaling Pathway As A Marker Of The Unfolded Protein Response In Patients With Acute Myeloid Leukemia, Nergi̇z Erkut, Turhan Köksal, Seli̇m Demi̇r, Ahmet Menteşe, Özlen Balta, Mehmet Sönmez

Turkish Journal of Medical Sciences

Background/aim: The protein kinase RNA-like endoplasmic reticulum kinase (PERK) pathway plays a critical role in preventing the accumulation of misfolded or unfolded proteins within the endoplasmic reticulum. In this study, the role of the PERK signaling pathway was evaluated in newly diagnosed, treatment-naïve patients with acute myeloid leukemia (AML).

Materials and methods: Plasma levels of eukaryotic translation initiation factor 2-alpha kinase 3 (eIF2AK3), glucose-regulated protein 78 (GRP78), activating transcription factor 6 (ATF6), CCAAT/enhancer-binding protein homologous protein (CHOP), hypoxia-inducible factor-1 alpha (HIF-1α), and caspase 3 were measured by enzyme-linked immunosorbent assay in peripheral blood samples obtained from AML patients and healthy …

Creating A Healthy Workplace Culture With A “Steps To Wellness” Initiative, Jennifer M. Clifton, Michael Caserta, Cheryl Armstrong, Katarina Friberg-Felsted, Jennifer Macali, Sara Simonsen

Creating Healthy Work Environments (CHWE)

Purpose: The aim of this project was to promote the health and wellness of nursing academia faculty and staff by implementing a physical movement initiative.

Background: Promoting the health and wellness of faculty and staff working in nursing academia is an important and timely initiative (Amaya et al., 2019; Mabona et al., 2022). Researchers have noted that an individual's lifestyle behaviors directly affect their work productivity, physical activity, and stress levels (Labrague et al., 2022; Reif et al., 2020; Stanulewicz et al., 2020). Amaya et al. (2019) suggested that institutions of higher education could improve work-life balance by “creating campus …

Green Vessel Signal On Multicolor Imaging As An Early Sign Of Ischemic Vasculitis In Irvan Syndrome: A Case Report, Daniel M. Markowitz, Jirat Nimworaphan, Carl Regillo, James P. Dunn, Robert C. Sergott

Wills Eye Hospital Papers

PURPOSE: Idiopathic retinitis, vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome is typically diagnosed after characteristic intravenous fluorescein angiography (IVFA) findings develop. This case demonstrates that identifying a green intravascular and perivascular signal on multicolor fundus imaging may be a potential noninvasive imaging sign for ischemic retinal vasculitis in IRVAN.

OBSERVATIONS: A 55-year-old female presented with bilateral optic disc edema and subtle peripapillary retinal vascular changes. Multicolor imaging showed a distinct green intravascular and perivascular signal before undergoing IVFA evaluation. Subsequent IVFA ultimately showed peripheral capillary nonperfusion, microaneurysms, and leakage consistent with IRVAN.

CONCLUSIONS AND IMPORTANCE: This case demonstrates the potential utility …

Colonisation, Globalisation And A Pandemic: Developing Understandings Of Inclusive Education In Malaysia, Vicky Bamsey, Yee Ling Lee, Moses Samuel

School of Law, Humanities and Social Sciences

This is a theoretical paper that examines how colonisation, globalisation and a crisis such as the Covid-19 pandemic have had a significant influence on the development of inclusive education policy and practice in Malaysia. Drawing on the ideas of dependency from Farid Alatas, and Carol Bacchi’s focus on the identification of the underlying problem within policies, as well as Stephen Ball’s policy cycle, we highlight how global events have repercussions at a policy level now and into the future. This paper contributes to the wider inclusive education debate through the innovative use of these three different theoretical lenses, informed by …

Prevalence Of Gout In The Sincan District Of Ankara, Türkiye: A Primary Care-Based Cross-Sectional Study, Riza Can Kardaş, Yasemi̇n Ünsal, Derya Yildirim, Hakan Tüzün, Mustafa Necmi̇ İlhan, Hami̇t Küçük, Abdurrahman Tufan, M. Aki̇f Öztürk

Turkish Journal of Medical Sciences

Background/aim: Gout, the most prevalent form of inflammatory arthritis, has shown a global increase in prevalence; however, data from Türkiye remain scarce, inconsistent, and largely confined to western regions. This study aimed to estimate the prevalence of gout among adults in the Sincan district of Ankara, Türkiye, and to provide updated data from a previously understudied region.

Materials and methods: This cross-sectional, community-based study employed a multistage design. Adults aged ≥18 years who presented to selected family health centers in Sincan between February and June 2023 were screened using a structured questionnaire. Individuals with suspected gout underwent comprehensive clinical evaluation, …

Sarcopenia In Atrial Fibrillation: A Prospective Study, Mehmet Aki̇f Topçuoğlu, Ezgi̇ Yilmaz, Di̇nç Doğan Öge, Ali̇ Nai̇m Ceren, Ridvan Muhammed Adin, Ethem Murat Arsava

Turkish Journal of Medical Sciences

Background/aim: The link between atrial fibrillation (AF) and lean body mass is unclear. This study presents the effects of AF on sarcopenia indices, including ultrasonographic muscle architecture.

Materials and methods: In this study conducted in neurology units, 72 subjects with AF (mean age: 71 ± 11years, 49% female) were compared with 538 without AF (mean age:66±12years; 53% female) in terms of sarcopenia indices [anthropometry; Short Physical Performance Battery (SPPB); hand grip strength (HGS); bioimpedance analysis (BIA) indices; skeletal muscle mass index (SMMI) normalized to weight, height and body mass index (BMI); and phase angle (PhA)]; muscle ultrasonography [thickness, cross-section area …

Levothyroxine Poisoning In Children: A Multicenter Study From Türkiye, Kübra Şen Küçük, Şule Demi̇r, Reyhan Deveci̇ Sevi̇m, Fatma Akgül, Gülşen Yalçin, Öznur Eser, Alkan Bal, Eli̇f Ergi̇n, Sercan Öztürk, Ahmet Anik

Turkish Journal of Medical Sciences

Background/aim: This study aimed to investigate the clinical features, laboratory findings, treatment approaches, and follow-up strategies employed in the management of pediatric patients with levothyroxine poisoning.

Materials and methods: This multicenter retrospective study included patients aged ≤18 years who presented with acute, single-episode levothyroxine ingestion to the pediatric emergency departments of six tertiary care centers between 2010 and 2023. Clinical data, laboratory findings, symptom onset and severity, and treatment modalities were extracted from medical records. Thyroid function tests (TFTs) were interpreted according to the age-specific reference ranges of each center. Treatment decisions, including gastric decontamination and pharmacologic therapy, were evaluated …

Developing Liposomal And Ethosomal Formulations With Potent Antioxidant And Cytotoxic Effects: Unleashing The Power Of Achillea Millefolium L., Esra Akkol, Sena Akçakaya Mutlu, Gökçe Şeker Karatoprak, Çi̇ğdem Yücel, Selen İlgün, Esra Köngül Şafak, Murat Koç

Turkish Journal of Medical Sciences

Background/aim: Achillea millefolium L., a plant rich in phenolics and flavonoids, has been shown to possess strong antioxidant and cytotoxic properties. However, no pharmaceutical formulations have yet been developed for this plant. This study aimed to create and characterize an A. millefolium extract with high antioxidant and cytotoxic activities.

Materials and methods: A total of 10 extracts were prepared from the plant’s aerial parts using ethanol concentrations ranging from 10% to 99.9%. The DPPH (1,1-diphenyl-2-picrylhydrazyl) and ABTS (2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) radical scavenging tests were used to assess the antioxidant properties of the extracts. Cytotoxic effects were assessed using the MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium …

Neuroendocrine Effects Of Exogenous Adropin Administration On The Hypothalamic Pituitary Testicular Axis In Male Rats, Ersen Eraslan, Ayhan Tanyeli̇, Mustafa Can Güler, Asli Özbek Bi̇lgi̇n, Fazi̇le Nur Eki̇nci̇ Akdemi̇r, Eli̇f Polat, Seli̇m Çomakli, Nezahat Kurt, Tuğba Bal Taştan

Turkish Journal of Medical Sciences

Background/aim: Obesity impairs male fertility through metabolic dysfunction, oxidative stress, and disruption of the hypothalamic– pituitary–testicular (HPT) axis. Adropin (ADR), a peptide hormone whose circulating levels are reduced in obesity, plays emerging roles in metabolic homeostasis; however, its involvement in reproductive endocrine regulation remains unclear. The present study was conducted in healthy, nonobese male rats and aimed to investigate the neuroendocrine and testicular effects of exogenous ADR administration, focusing on circulating reproductive hormones, hypothalamic regulatory peptides, and testicular antioxidant pathways.

Materials and methods: Thirty-two male Wistar rats were randomized into control, sham, low-dose ADR (4 μg/kg/day), and high-dose ADR (40 …

Association Of Mir-34a With Metastatic Progression Through The Foxo3a–Sirt1 Regulatory Axis In Breast Cancer, Banu Şahi̇n, İlker Batuhan Bural, Hüseyi̇n Özcan, Sendegül Yildirim, Gamze Tanriöver, Şükran Burçak Yoldaş

Turkish Journal of Medical Sciences

Background/aim: Breast cancer represents the foremost cause of cancer-related mortality among women worldwide and is characterized by a markedly high metastatic potential, contributing substantially to its clinical severity and poor prognosis. This study aimed to evaluate the interrelationship among silent information regulator (SIRT1), Forkhead box O3a (FoxO3a), and microRNA-34a (miR- 34a), the latter of which promotes apoptosis by suppressing the proliferation, migration, and invasion of breast cancer cells. Specifically, we investigated the tumor microenvironment associated with metastatic progression of malignant primary tumors, the influence of nonmetastatic (benign) tumors, and the potential roles of these proteins in both primary tumor development …

The Indiana Statesman, February 12, 2026, Indiana State University

Student Newspaper

SGA candidates make their case; Clapp & Tesmer; Lancaster & Pekny

Keeping Up With… Graduate Student Research Support Models, Giovanna Colosi

Librarian Publications

Graduate education plays a central role in many institutions’ academic missions and revenue models, yet national data from the Council of Graduate Schools (CGS) indicate that enrollment and application patterns have shifted unevenly over the past decade, varying by discipline, credential type, and institutional context. At the same time, the graduate student population is increasingly diverse in modality and life stage, with more students enrolling part time, studying online or in hybrid formats, and returning mid-career. These changes present significant implications for academic and research libraries, particularly as graduate students’ research needs remain intensive while their schedules and pathways grow …

Navigating Analytical Challenges In Clinical Trials Using The Multiverse Approach, Alexander O. Crenshaw, Nicole Pukay-Martin, Anne Wagner

Faculty Articles

Making decisions regarding data processing and analysis are crucial steps toward extracting insights from data in clinical trials. Trial registries like clinicaltrials.gov promote transparency about these decisions and encourage making them in advance. However, clinical studies often face decisions with multiple reasonable options outside the bounds of preregistration, such as when studies conduct post hoc analyses, deviate from preregistered plans, or simply were not preregistered. Additionally, even a priori decisions often have multiple reasonable options from which to choose. Methods that maximize transparency and minimize bias in such situations are needed. This paper advocates for applying a “multiverse” approach to …

A Rare And Challenging Polymicrobial Pleural Infection Involving Cupriavidus Pauculus In A Patient With Rheumatoid Arthritis And Multiple Complications, Moiz Ahmed Khan, Syeda Samiya Kamal, Muhammad Muneeb, Summaya Zafar

The University of Louisville Journal of Respiratory Infections

A 58-year-old female with a 15-year history of rheumatoid arthritis (RA) and a history of treatment consisting of methotrexate, hydroxychloroquine, leflunomide, and chronic prednisolone therapy, presented with fever, productive cough, dyspnea, and left leg cellulitis. She developed septic shock complicated by tension pneumothorax requiring emergency thoracostomy and non-ST-elevation myocardial infarction (NSTEMI). Pleural fluid culture grew Cupriavidus pauculus, a rare environmental gram-negative bacillus, alongside Burkholderia cepacia and Candida parapsilosis, indicating polymicrobial infection which was most likely predisposed by patient's immunosuppressed state from RA and prolonged steroid use. Treatment consisted of trimethoprim/sulfamethoxazole, meropenem, fluconazole, and cardiopulmonary support, and culminated in …

Trends In The Psychedelic Renaissance: Applying Artificial Intelligence To Measure Media Portrayal Of Psychedelic Drugs In The 21st Century, David A Bender, Harrison M Dunn, Arushi D Mohite, Akila Anandarajah, Jacob Steinle, Suraj Shankar, Brandon Kiley, Sara Martin, Rishi Gonuguntla, Mia Stonov, Nithya Pippala, Rana Abdalla, Madison K Stille, Gibson Werner, Melinda Daniels-Tineo, Hannah Wang, Sonali Sharma, Jatin Sridhar, Adebusola Adeyemi, Kayla Smart, Baris C Ercal, Et Al.

2020-Current year OA Pubs

BACKGROUND: The relationship between media portrayal of psychedelic drugs, scientific research and drug policy is an area of debate.

AIMS: To apply artificial intelligence technology to measure trends in media sentiment towards the therapeutic potential of psychedelic drugs.

METHOD: Up to 300 of the most relevant articles from Google News searches for the term 'psychedelics' were sampled for each year from 2000 to 2025. A large language model, ChatGPT, evaluated subject matter and sentiment.

RESULTS: In total, 88.3% of screened URLs (3308 of 3747) were included in the analysis. The proportion of articles focusing on the therapeutic potential of psychedelics …

Spartan Daily, February 12, 2026, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2026

Volume 166, Issue 10

Community Or Commodity? Nurse Perceptions Of Support From Healthcare Institutions And The Community, Jacqueline Christianson, Madaline Mccarthy, Bonnie Sommers-Olson, Jill Guttormson, Norah Louise Johnson

Creating Healthy Work Environments (CHWE)

Purpose: High stress, moral distress, and burnout are common in nursing workplaces and are associated with poorer patient and nurse outcomes. Research showed that excessive work-related stress was a growing problem for the nursing workforce prior to the Covid-19 pandemic (Bakhamis et al., 2019). However, working conditions became considerably more stressful because pandemic-related workplace changes made previous methods of caring, connecting empathetically with patients, and behaving altruistically difficult to impossible for nurses to achieve (Foli et al., 2021; McAndrew et al., 2023). Community connectedness and mutual social support may be buffers against the harmful effects of chronic occupational stress and …