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Articles 38281 - 38310 of 1737528
Full-Text Articles in Entire DC Network
Trends In The Psychedelic Renaissance: Applying Artificial Intelligence To Measure Media Portrayal Of Psychedelic Drugs In The 21st Century, David A. Bender, Harrison M. Dunn, Amanda Pekau, Arushi D. Mohite, Akila Anandarajah, Brendan D. Ross, Jacob Steinle, Suraj Shankar, Brandon Kiley, Umer Jalil
Trends In The Psychedelic Renaissance: Applying Artificial Intelligence To Measure Media Portrayal Of Psychedelic Drugs In The 21st Century, David A. Bender, Harrison M. Dunn, Amanda Pekau, Arushi D. Mohite, Akila Anandarajah, Brendan D. Ross, Jacob Steinle, Suraj Shankar, Brandon Kiley, Umer Jalil
School of Medicine Publications
Background: The relationship between media portrayal of psychedelic drugs, scientific research and drug policy is an area of debate.
Aims: To apply artificial intelligence technology to measure trends in media sentiment towards the therapeutic potential of psychedelic drugs.
Method: Up to 300 of the most relevant articles from Google News searches for the term 'psychedelics' were sampled for each year from 2000 to 2025. A large language model, ChatGPT, evaluated subject matter and sentiment.
Results: In total, 88.3% of screened URLs (3308 of 3747) were included in the analysis. The proportion of articles focusing on the therapeutic potential of psychedelics …
Beyond Rationality: The Role Of Emotions In Communicative Planning, Minji Cho
Beyond Rationality: The Role Of Emotions In Communicative Planning, Minji Cho
Urban Studies and Planning Faculty Publications and Presentations
The impact of emotional dynamics has been overlooked within the field of planning. Traditional communicative planning theory, rooted in Habermas’ model of communication, typically propose that emotions should be managed to facilitate rational discussions that lead to logical agreements. Conversely, some research contends that emotions are not illogical or hazardous elements to be restrained during deliberation; instead, they are a topic requiring thorough investigation to create improved public forums. We investigate this tension by analysing facework during a land-use dispute at at the Gongjin Elementary School site in Seoul, South Korea. Our analysis reveals that facework not only impedes the …
Clinical Outcome Of Extremity Arterial Injuries In The Modern Era, Ali̇ Kuşsan, Selçuk Coşkun, Alp Şener, Ferhat İçme, Pinar Köksal Coşkun, Gülhan Kurtoğlu Çeli̇k
Clinical Outcome Of Extremity Arterial Injuries In The Modern Era, Ali̇ Kuşsan, Selçuk Coşkun, Alp Şener, Ferhat İçme, Pinar Köksal Coşkun, Gülhan Kurtoğlu Çeli̇k
Turkish Journal of Medical Sciences
Background/aim: Extremity arterial injuries (EAIs) present a significant clinical challenge due to the risk of limb ischemia, amputation, and mortality. This retrospective cohort study aimed to delineate the clinical course, treatment strategies, and patient outcomes following trauma-induced EAIs, and to identify independent predictors of adverse outcomes.
Materials and methods: Retrospectively analyzed were data from 168 consecutive patients with traumatic EAIs who underwent computed tomography angiography at a tertiary care center between 2019 and 2025. Data extracted from electronic medical records included demographics, injury mechanisms, clinical presentation, laboratory findings, imaging results, treatment modalities (primary repair, grafting, endovascular intervention, conservative management), and …
The Perk Signaling Pathway As A Marker Of The Unfolded Protein Response In Patients With Acute Myeloid Leukemia, Nergi̇z Erkut, Turhan Köksal, Seli̇m Demi̇r, Ahmet Menteşe, Özlen Balta, Mehmet Sönmez
The Perk Signaling Pathway As A Marker Of The Unfolded Protein Response In Patients With Acute Myeloid Leukemia, Nergi̇z Erkut, Turhan Köksal, Seli̇m Demi̇r, Ahmet Menteşe, Özlen Balta, Mehmet Sönmez
Turkish Journal of Medical Sciences
Background/aim: The protein kinase RNA-like endoplasmic reticulum kinase (PERK) pathway plays a critical role in preventing the accumulation of misfolded or unfolded proteins within the endoplasmic reticulum. In this study, the role of the PERK signaling pathway was evaluated in newly diagnosed, treatment-naïve patients with acute myeloid leukemia (AML).
Materials and methods: Plasma levels of eukaryotic translation initiation factor 2-alpha kinase 3 (eIF2AK3), glucose-regulated protein 78 (GRP78), activating transcription factor 6 (ATF6), CCAAT/enhancer-binding protein homologous protein (CHOP), hypoxia-inducible factor-1 alpha (HIF-1α), and caspase 3 were measured by enzyme-linked immunosorbent assay in peripheral blood samples obtained from AML patients and healthy …
Creating A Healthy Workplace Culture With A “Steps To Wellness” Initiative, Jennifer M. Clifton, Michael Caserta, Cheryl Armstrong, Katarina Friberg-Felsted, Jennifer Macali, Sara Simonsen
Creating A Healthy Workplace Culture With A “Steps To Wellness” Initiative, Jennifer M. Clifton, Michael Caserta, Cheryl Armstrong, Katarina Friberg-Felsted, Jennifer Macali, Sara Simonsen
Creating Healthy Work Environments (CHWE)
Purpose: The aim of this project was to promote the health and wellness of nursing academia faculty and staff by implementing a physical movement initiative.
Background: Promoting the health and wellness of faculty and staff working in nursing academia is an important and timely initiative (Amaya et al., 2019; Mabona et al., 2022). Researchers have noted that an individual's lifestyle behaviors directly affect their work productivity, physical activity, and stress levels (Labrague et al., 2022; Reif et al., 2020; Stanulewicz et al., 2020). Amaya et al. (2019) suggested that institutions of higher education could improve work-life balance by “creating campus …
Green Vessel Signal On Multicolor Imaging As An Early Sign Of Ischemic Vasculitis In Irvan Syndrome: A Case Report, Daniel M. Markowitz, Jirat Nimworaphan, Carl Regillo, James P. Dunn, Robert C. Sergott
Green Vessel Signal On Multicolor Imaging As An Early Sign Of Ischemic Vasculitis In Irvan Syndrome: A Case Report, Daniel M. Markowitz, Jirat Nimworaphan, Carl Regillo, James P. Dunn, Robert C. Sergott
Wills Eye Hospital Papers
PURPOSE: Idiopathic retinitis, vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome is typically diagnosed after characteristic intravenous fluorescein angiography (IVFA) findings develop. This case demonstrates that identifying a green intravascular and perivascular signal on multicolor fundus imaging may be a potential noninvasive imaging sign for ischemic retinal vasculitis in IRVAN.
OBSERVATIONS: A 55-year-old female presented with bilateral optic disc edema and subtle peripapillary retinal vascular changes. Multicolor imaging showed a distinct green intravascular and perivascular signal before undergoing IVFA evaluation. Subsequent IVFA ultimately showed peripheral capillary nonperfusion, microaneurysms, and leakage consistent with IRVAN.
CONCLUSIONS AND IMPORTANCE: This case demonstrates the potential utility …
The Indiana Statesman, February 12, 2026, Indiana State University
The Indiana Statesman, February 12, 2026, Indiana State University
Student Newspaper
SGA candidates make their case; Clapp & Tesmer; Lancaster & Pekny
Keeping Up With… Graduate Student Research Support Models, Giovanna Colosi
Keeping Up With… Graduate Student Research Support Models, Giovanna Colosi
Librarian Publications
Graduate education plays a central role in many institutions’ academic missions and revenue models, yet national data from the Council of Graduate Schools (CGS) indicate that enrollment and application patterns have shifted unevenly over the past decade, varying by discipline, credential type, and institutional context. At the same time, the graduate student population is increasingly diverse in modality and life stage, with more students enrolling part time, studying online or in hybrid formats, and returning mid-career. These changes present significant implications for academic and research libraries, particularly as graduate students’ research needs remain intensive while their schedules and pathways grow …
Navigating Analytical Challenges In Clinical Trials Using The Multiverse Approach, Alexander O. Crenshaw, Nicole Pukay-Martin, Anne Wagner
Navigating Analytical Challenges In Clinical Trials Using The Multiverse Approach, Alexander O. Crenshaw, Nicole Pukay-Martin, Anne Wagner
Faculty Articles
Making decisions regarding data processing and analysis are crucial steps toward extracting insights from data in clinical trials. Trial registries like clinicaltrials.gov promote transparency about these decisions and encourage making them in advance. However, clinical studies often face decisions with multiple reasonable options outside the bounds of preregistration, such as when studies conduct post hoc analyses, deviate from preregistered plans, or simply were not preregistered. Additionally, even a priori decisions often have multiple reasonable options from which to choose. Methods that maximize transparency and minimize bias in such situations are needed. This paper advocates for applying a “multiverse” approach to …
A Rare And Challenging Polymicrobial Pleural Infection Involving Cupriavidus Pauculus In A Patient With Rheumatoid Arthritis And Multiple Complications, Moiz Ahmed Khan, Syeda Samiya Kamal, Muhammad Muneeb, Summaya Zafar
A Rare And Challenging Polymicrobial Pleural Infection Involving Cupriavidus Pauculus In A Patient With Rheumatoid Arthritis And Multiple Complications, Moiz Ahmed Khan, Syeda Samiya Kamal, Muhammad Muneeb, Summaya Zafar
The University of Louisville Journal of Respiratory Infections
A 58-year-old female with a 15-year history of rheumatoid arthritis (RA) and a history of treatment consisting of methotrexate, hydroxychloroquine, leflunomide, and chronic prednisolone therapy, presented with fever, productive cough, dyspnea, and left leg cellulitis. She developed septic shock complicated by tension pneumothorax requiring emergency thoracostomy and non-ST-elevation myocardial infarction (NSTEMI). Pleural fluid culture grew Cupriavidus pauculus, a rare environmental gram-negative bacillus, alongside Burkholderia cepacia and Candida parapsilosis, indicating polymicrobial infection which was most likely predisposed by patient's immunosuppressed state from RA and prolonged steroid use. Treatment consisted of trimethoprim/sulfamethoxazole, meropenem, fluconazole, and cardiopulmonary support, and culminated in …
Trends In The Psychedelic Renaissance: Applying Artificial Intelligence To Measure Media Portrayal Of Psychedelic Drugs In The 21st Century, David A Bender, Harrison M Dunn, Arushi D Mohite, Akila Anandarajah, Jacob Steinle, Suraj Shankar, Brandon Kiley, Sara Martin, Rishi Gonuguntla, Mia Stonov, Nithya Pippala, Rana Abdalla, Madison K Stille, Gibson Werner, Melinda Daniels-Tineo, Hannah Wang, Sonali Sharma, Jatin Sridhar, Adebusola Adeyemi, Kayla Smart, Baris C Ercal, Et Al.
Trends In The Psychedelic Renaissance: Applying Artificial Intelligence To Measure Media Portrayal Of Psychedelic Drugs In The 21st Century, David A Bender, Harrison M Dunn, Arushi D Mohite, Akila Anandarajah, Jacob Steinle, Suraj Shankar, Brandon Kiley, Sara Martin, Rishi Gonuguntla, Mia Stonov, Nithya Pippala, Rana Abdalla, Madison K Stille, Gibson Werner, Melinda Daniels-Tineo, Hannah Wang, Sonali Sharma, Jatin Sridhar, Adebusola Adeyemi, Kayla Smart, Baris C Ercal, Et Al.
2020-Current year OA Pubs
BACKGROUND: The relationship between media portrayal of psychedelic drugs, scientific research and drug policy is an area of debate.
AIMS: To apply artificial intelligence technology to measure trends in media sentiment towards the therapeutic potential of psychedelic drugs.
METHOD: Up to 300 of the most relevant articles from Google News searches for the term 'psychedelics' were sampled for each year from 2000 to 2025. A large language model, ChatGPT, evaluated subject matter and sentiment.
RESULTS: In total, 88.3% of screened URLs (3308 of 3747) were included in the analysis. The proportion of articles focusing on the therapeutic potential of psychedelics …
Community Or Commodity? Nurse Perceptions Of Support From Healthcare Institutions And The Community, Jacqueline Christianson, Madaline Mccarthy, Bonnie Sommers-Olson, Jill Guttormson, Norah Louise Johnson
Community Or Commodity? Nurse Perceptions Of Support From Healthcare Institutions And The Community, Jacqueline Christianson, Madaline Mccarthy, Bonnie Sommers-Olson, Jill Guttormson, Norah Louise Johnson
Creating Healthy Work Environments (CHWE)
Purpose: High stress, moral distress, and burnout are common in nursing workplaces and are associated with poorer patient and nurse outcomes. Research showed that excessive work-related stress was a growing problem for the nursing workforce prior to the Covid-19 pandemic (Bakhamis et al., 2019). However, working conditions became considerably more stressful because pandemic-related workplace changes made previous methods of caring, connecting empathetically with patients, and behaving altruistically difficult to impossible for nurses to achieve (Foli et al., 2021; McAndrew et al., 2023). Community connectedness and mutual social support may be buffers against the harmful effects of chronic occupational stress and …
Quaker Campus, February 12, 2026 (Vol. 24, Issue 8), Whittier College
Quaker Campus, February 12, 2026 (Vol. 24, Issue 8), Whittier College
Quaker Campus
No abstract provided.
Individualized Respiratory Exercise Device Originated In Türkiye: Design, Prototype, And First Results, Çi̇ğdem Emi̇rza Ci̇lbi̇r, Özge Ertan Harputlu, Hi̇kmet Uçgun, Büşra Ülker Ekşi̇, Sarper Kaya, Esen Kiyan, Gökşen Kuran Aslan, Buket Akinci
Individualized Respiratory Exercise Device Originated In Türkiye: Design, Prototype, And First Results, Çi̇ğdem Emi̇rza Ci̇lbi̇r, Özge Ertan Harputlu, Hi̇kmet Uçgun, Büşra Ülker Ekşi̇, Sarper Kaya, Esen Kiyan, Gökşen Kuran Aslan, Buket Akinci
Turkish Journal of Medical Sciences
Background/aim: Respiratory muscle training (RMT) and breathing exercises are crucial components in cardiopulmonary rehabilitation. RMT includes inspiratory muscle training (IMT) and expiratory muscle training (EMT); however, existing RMT devices typically support only one of these. Incentive spirometers, which also provide visual feedback for breathing exercises, are frequently used. Achieving an RMT program requires multiple devices, which increases both the cost and complexity of the training regimen. This study aimed to design, calibrate, and test a novel individualized respiratory exercise device that integrates both IMT and EMT functions into a single unit, thereby offering a cost-effective, user-friendly alternative for comprehensive cardiopulmonary …
Radial Peripapillary Capillary Changes And Retinal Nerve Fiber Layer Alterations In Diabetic Foot Ulcers With Mild-To-Moderate Nonproliferative Diabetic Retinopathy: An Octa Study, Eyüpcan Şensoy, Hi̇kmet Erhan Güven, Mehmet Çitirik
Radial Peripapillary Capillary Changes And Retinal Nerve Fiber Layer Alterations In Diabetic Foot Ulcers With Mild-To-Moderate Nonproliferative Diabetic Retinopathy: An Octa Study, Eyüpcan Şensoy, Hi̇kmet Erhan Güven, Mehmet Çitirik
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the impact of diabetic foot ulcers (DFUs) on retinal microvascular changes, specifically the radial peripapillary capillary (RPC) vessel density and retinal nerve fiber layer (RNFL) thickness in patients with mild-to-moderate nonproliferative diabetic retinopathy (NPDR).
Materials and methods: Ninety participants were enrolled and divided into three groups: 30 patients with DFUs and mild-to-moderate NPDR, 30 patients with NPDR but without DFUs, and 30 healthy controls. RPC density and RNFL thickness were evaluated using optical coherence tomography angiography (OCTA), a noninvasive imaging method. Comparisons between groups were made with statistical adjustments, including optic disc area.
Results: …
Evaluation Of Colonization With Multidrug-Resistant Microorganisms And The Incidence Of Attributable Infections In Patients Undergoing Hematopoietic Stem Cell Transplantation, Burcu Çalişkan Demi̇rkiran, Gülşen İskender, İpek Mumcuoğlu, Duygu Mert, Si̇nan Dal, Tuba Dal, Semra Tunçbi̇lek, Mustafa Ertek, Fevzi̇ Altuntaş
Evaluation Of Colonization With Multidrug-Resistant Microorganisms And The Incidence Of Attributable Infections In Patients Undergoing Hematopoietic Stem Cell Transplantation, Burcu Çalişkan Demi̇rkiran, Gülşen İskender, İpek Mumcuoğlu, Duygu Mert, Si̇nan Dal, Tuba Dal, Semra Tunçbi̇lek, Mustafa Ertek, Fevzi̇ Altuntaş
Turkish Journal of Medical Sciences
Background/aim: The global rise in multidrug-resistant organisms (MDROs) has led to an increased incidence of MDRO infections following hematopoietic stem cell transplantation (HSCT), particularly during the preengraftment period. The objective of this study was to evaluate the relationship between pretransplant colonization by MDROs or carbapenem-resistant Enterobacterales (CRE) and the occurrence of infections caused by phenotypically similar microorganisms during the preengraftment period, as well as to assess the clinical outcomes of patients colonized with MDROs prior to transplantation.
Materials and methods: This prospective cohort study included patients diagnosed with hematological malignancies who underwent HSCT at the bone marrow transplant unit of …
The Impact Of Fall History On Instability, Disability, And Anxiety In Patients With Chronic Neck Pain, Bülent Bozyi̇ği̇t, Emre Söylemez, Aydin Si̇nan Apaydin
The Impact Of Fall History On Instability, Disability, And Anxiety In Patients With Chronic Neck Pain, Bülent Bozyi̇ği̇t, Emre Söylemez, Aydin Si̇nan Apaydin
Turkish Journal of Medical Sciences
Background/aim: This study aimed to investigate the impact of fall history on postural stability, disability, and anxiety in individuals with chronic neck pain (CNP). It was hypothesized that patients with a history of falls would exhibit greater postural instability, perceived disability, and anxiety levels compared with those without a fall history and healthy controls.
Materials and methods: A total of 62 participants were included: 16 CNP patients with a history of falling (Group Ia), 21 CNP patients without falls (Group Ib), and 25 healthy controls. Assessments included the Neck Disability Index (NDI), Beck Anxiety Inventory (BAI), and Visual Analog Scale …
Levothyroxine Poisoning In Children: A Multicenter Study From Türkiye, Kübra Şen Küçük, Şule Demi̇r, Reyhan Deveci̇ Sevi̇m, Fatma Akgül, Gülşen Yalçin, Öznur Eser, Alkan Bal, Eli̇f Ergi̇n, Sercan Öztürk, Ahmet Anik
Levothyroxine Poisoning In Children: A Multicenter Study From Türkiye, Kübra Şen Küçük, Şule Demi̇r, Reyhan Deveci̇ Sevi̇m, Fatma Akgül, Gülşen Yalçin, Öznur Eser, Alkan Bal, Eli̇f Ergi̇n, Sercan Öztürk, Ahmet Anik
Turkish Journal of Medical Sciences
Background/aim: This study aimed to investigate the clinical features, laboratory findings, treatment approaches, and follow-up strategies employed in the management of pediatric patients with levothyroxine poisoning.
Materials and methods: This multicenter retrospective study included patients aged ≤18 years who presented with acute, single-episode levothyroxine ingestion to the pediatric emergency departments of six tertiary care centers between 2010 and 2023. Clinical data, laboratory findings, symptom onset and severity, and treatment modalities were extracted from medical records. Thyroid function tests (TFTs) were interpreted according to the age-specific reference ranges of each center. Treatment decisions, including gastric decontamination and pharmacologic therapy, were evaluated …
Effects Of Transversus Abdominis And Erector Spinae Plane Blocks On Postoperative Pain Control And Postpartum Depression After Cesarean Section: A Randomized Prospective Study, Hi̇lal Bi̇radli, Feyza Çalişir, Alev Özer
Effects Of Transversus Abdominis And Erector Spinae Plane Blocks On Postoperative Pain Control And Postpartum Depression After Cesarean Section: A Randomized Prospective Study, Hi̇lal Bi̇radli, Feyza Çalişir, Alev Özer
Turkish Journal of Medical Sciences
Background/aim: Effective postoperative pain management after cesarean section is essential for maternal recovery. Poor pain control can lead to complications, including postpartum depression. This study aimed to compare the postoperative analgesic efficacy of erector spinae plane (ESP) and transversus abdominis plane (TAP) blocks following cesarean section, with a particular focus on their potential impact on postpartum depression.
Materials and methods: Sixty patients were randomly assigned to receive either an ESP block (Group E, n = 30) or a TAP block (Group T, n = 30) after cesarean section. Pain severity was assessed using a visual analog scale (VAS), and the …
Examination Of Sexual Health Literacy And Cyberchondria Levels In Women With Vaginismus, Gonca Türker Ergün, Cemal Ünlü, Ayşe Kuyulu Akman, Elçi̇n İşlek Seçen, Razi̇ye Toksöz
Examination Of Sexual Health Literacy And Cyberchondria Levels In Women With Vaginismus, Gonca Türker Ergün, Cemal Ünlü, Ayşe Kuyulu Akman, Elçi̇n İşlek Seçen, Razi̇ye Toksöz
Turkish Journal of Medical Sciences
Background/aim: This study aimed to compare sexual health literacy and cyberchondria levels between women who had been diagnosed with vaginismus and those who had not.
Materials and methods: The research was conducted as a prospective cohort study including 60 women over the age of 18 who were married and unable to engage in sexual intercourse due to primary vaginismus and 60 sexually active married women without vaginismus. Data collection tools included a patient information form, the Cyberchondria Severity Scale (CSS-12-TR), and the Sexual Health Literacy Scale (SHLS).
Results: The median age of the women diagnosed with vaginismus was 27 (21–54) …
Cd20 Molecule Deficiency And Carrier Frequency: A Village-Based Screening Study, Ebru Sümen, Mehmet Ali̇ Karaselek, Serkan Küççüktürk, Tuğçe Duran, Büşra Yüksel, Mustafa Gençeli̇, Ayşe Sümeyra Engi̇n, Muhammed Furkan Erden, Tuğba Esra Pekcandanoğlu, Bi̇lal Bostan, Mahmut Esad Yurtseven, Nazi̇re Nur Onat, Şükrü Nai̇l Güner, Sevgi̇ Keleş, İsmai̇l Rei̇sli̇
Cd20 Molecule Deficiency And Carrier Frequency: A Village-Based Screening Study, Ebru Sümen, Mehmet Ali̇ Karaselek, Serkan Küççüktürk, Tuğçe Duran, Büşra Yüksel, Mustafa Gençeli̇, Ayşe Sümeyra Engi̇n, Muhammed Furkan Erden, Tuğba Esra Pekcandanoğlu, Bi̇lal Bostan, Mahmut Esad Yurtseven, Nazi̇re Nur Onat, Şükrü Nai̇l Güner, Sevgi̇ Keleş, İsmai̇l Rei̇sli̇
Turkish Journal of Medical Sciences
Background/aim: CD20 deficiency is an autosomal recessive inborn error of immunity (IEI), and the only known affected individual worldwide has been under follow-up in our clinic. Because the consanguineous parents of the index patient are putative carriers, we hypothesized that additional individuals with reduced CD20 expression might exist within their village population. This study aimed to evaluate clinical features associated with IEI and to identify individuals displaying CD20 mean fluorescence intensity (MFI) patterns consistent with putative carrier status, while also providing appropriate genetic counseling.
Materials and methods: This cross-sectional screening study was conducted in December 2024 in Çukurbağ village. Participants …
Association Between Frailty Status And Pain, Balance, And Quality Of Life In Patients With Lumbar Spinal Stenosis, Musa Güneş, Aydin Si̇nan Apaydin
Association Between Frailty Status And Pain, Balance, And Quality Of Life In Patients With Lumbar Spinal Stenosis, Musa Güneş, Aydin Si̇nan Apaydin
Turkish Journal of Medical Sciences
Background/aim: Frailty is a clinical syndrome that affects individuals physically and psychosocially. However, the association between lumbar spinal stenosis (LSS) and frailty remains unclear. This study aimed to compare pain, balance, disability, fear of falling, and quality of life between patients with LSS with and without frailty.
Materials and methods: This cross-sectional study included 43 frail and 48 nonfrail patients with LSS according to the frailty criteria of Fried et al. Pain intensity (numeric rating scale [NRS]), static balance (single leg stance test [SLST]), dynamic balance (Timed Up and Go test [TUG]), disability (Oswestry Disability Index [ODI]), fear of falling …
The Impact Of Covid-19 On Healthcare Workers: Risk Factors, Sources Of Infection, And Sickness Absenteeism, Ezgi̇ Gülten, Güle Çinar, İrem Akdemi̇r, Eli̇f Muki̇me Saricaoğlu, İlkay Taşdan, Emi̇ne Atmaca, Si̇bel Kaymakçi, Fatma Şanal, Di̇lek Sevi̇m Akdaş, Arzu Büyüm, Gülşah Kocaali̇, Safi̇ye Tarakçi, Ati̇lla Hali̇l Elhan, Mehmet Serhat Bi̇rengel, Kemal Osman Memi̇koğlu, Alpay Azap
The Impact Of Covid-19 On Healthcare Workers: Risk Factors, Sources Of Infection, And Sickness Absenteeism, Ezgi̇ Gülten, Güle Çinar, İrem Akdemi̇r, Eli̇f Muki̇me Saricaoğlu, İlkay Taşdan, Emi̇ne Atmaca, Si̇bel Kaymakçi, Fatma Şanal, Di̇lek Sevi̇m Akdaş, Arzu Büyüm, Gülşah Kocaali̇, Safi̇ye Tarakçi, Ati̇lla Hali̇l Elhan, Mehmet Serhat Bi̇rengel, Kemal Osman Memi̇koğlu, Alpay Azap
Turkish Journal of Medical Sciences
Background/aim: Healthcare workers (HCWs) face increased risks of COVID-19 infection due to occupational exposure. Understanding infection sources, risk factors, and workforce losses is crucial for mitigating these impacts in future pandemics. This study aimed to evaluate the risk factors, infection sources, and sickness absenteeism among HCWs diagnosed with SARS-CoV-2 infection, providing insights to enhance infection control strategies.
Materials and methods: The study included 2153 HCWs diagnosed with SARS-CoV-2 between March 2020 and February 2023 at a tertiary care hospital in Türkiye. Demographic, clinical, and professional characteristics, personal protective equipment (PPE) usage, infection sources, and vaccination data were analyzed. Statistical analyses …
Involvement Of Swap-70 In Proteolipid Protein-Induced Experimental Autoimmune Encephalomyelitis, Canan Ulusoy, Gi̇zem Koral, Fatma Akpunar Salman, Meli̇s Şen, Emi̇ne Şekerdağ Kiliç, Recai̇ Türkoğlu, Cem İsmai̇l Küçükali̇, Yasemi̇n Gürsoy Özdemi̇r, Vuslat Yilmaz, Erdem Tüzün
Involvement Of Swap-70 In Proteolipid Protein-Induced Experimental Autoimmune Encephalomyelitis, Canan Ulusoy, Gi̇zem Koral, Fatma Akpunar Salman, Meli̇s Şen, Emi̇ne Şekerdağ Kiliç, Recai̇ Türkoğlu, Cem İsmai̇l Küçükali̇, Yasemi̇n Gürsoy Özdemi̇r, Vuslat Yilmaz, Erdem Tüzün
Turkish Journal of Medical Sciences
Background/aim: Multiple sclerosis (MS) is a chronic demyelinating inflammatory disease of the central nervous system. Studies have shown that B cells may play an important role in the induction and progression of MS. Switch-associated protein 70 (SWAP-70) is a signal transduction molecule abundantly expressed in B cells and involved in B-cell polarization, directed migration, endothelial cell adhesion, and tissue homing. B-cell stimuli increase its expression. SWAP-70 has been implicated in the pathogenesis of autoimmune disorders, including MS. This study aims to investigate the effects of acquired SWAP-70 inhibition on immune cell subsets in experimental autoimmune encephalomyelitis (EAE).
Materials and methods: …
Oleanolic Acid–Chitosan Compound Inhibits Mitochondrial Autophagy And Malignant Transformation Of Lung Cancer Through The Pten/Akt Pathway, Abuli̇mi̇ti̇ Abulai̇ti̇, Xi̇aohong Sun, Waresijiang Yibulayin, Dan He, Kemi̇ng Xu, Xi̇ayi̇mai̇erdan Yi̇bulayi̇n
Oleanolic Acid–Chitosan Compound Inhibits Mitochondrial Autophagy And Malignant Transformation Of Lung Cancer Through The Pten/Akt Pathway, Abuli̇mi̇ti̇ Abulai̇ti̇, Xi̇aohong Sun, Waresijiang Yibulayin, Dan He, Kemi̇ng Xu, Xi̇ayi̇mai̇erdan Yi̇bulayi̇n
Turkish Journal of Medical Sciences
Background/aim: Oleanolic acid–chitosan compound (OAC) shows potent antinonsmall cell lung cancer (NSCLC) activity, but its mechanisms remain unclear. This study elucidates how OAC modulates autophagy and apoptosis via the Phosphatase and Tensin Homolog/Protein Kinase B (PTEN/AKT) signaling pathway.
Materials and methods: Oleanolic acid was coupled with chitosan to synthesize OAC. A549 and MRC-5 cells were cultured in Dulbecco’s Modified Eagle Medium and Minimum Essential Medium, respectively, supplemented with 10% fetal bovine serum and penicillin–streptomycin. Cells were pretreated with chloroquine before OAC treatment. Cell viability was assessed using the CCK- 8 assay, while 5-bromo-2′-deoxyuridine (BrdU) and colony formation tests were employed …
The Prevalence And Impact Of Workplace Violence In Community Pharmacies: A Mixed-Methods Study, Hi̇lal İlbars, Berna Terzi̇oğlu Bebi̇toğlu, Seyhan Hidiroğlu, Fatma Burcu Doğanç, Yağiz Varol
The Prevalence And Impact Of Workplace Violence In Community Pharmacies: A Mixed-Methods Study, Hi̇lal İlbars, Berna Terzi̇oğlu Bebi̇toğlu, Seyhan Hidiroğlu, Fatma Burcu Doğanç, Yağiz Varol
Turkish Journal of Medical Sciences
Background/aim: Pharmacists and pharmacy technicians employed in community pharmacies face a considerable risk of workplace violence, which can negatively influence their job satisfaction, productivity, and mental well-being. This study examined the prevalence and consequences of workplace violence in community pharmacies in Ankara through a mixed-methods design integrating cross-sectional survey data with qualitative insights.
Materials and methods: The target population included pharmacists and pharmacy technicians. We examined demographic factors, psychological outcomes, and the nature of violent incidents. Data were obtained from a random sample of 355 community pharmacies using a 39-item survey and the depression anxiety stress scales (DASS-21), complemented by …
Preventing Spinal Muscular Atrophy Through The National Premarital Screening Program In Türkiye: An Economic Comparison With Treatment Costs, Gamze Dur, Gülcan Teci̇rli̇, Nurullah Okumuş
Preventing Spinal Muscular Atrophy Through The National Premarital Screening Program In Türkiye: An Economic Comparison With Treatment Costs, Gamze Dur, Gülcan Teci̇rli̇, Nurullah Okumuş
Turkish Journal of Medical Sciences
Background/aim: Spinal muscular atrophy (SMA) is a severe neuromuscular disorder with high treatment costs and significant psychosocial burden. In 2021, Türkiye launched a national premarital SMA carrier screening program integrated with in vitro fertilization (IVF) with preimplantation genetic testing (PGT) services for couples identified as carriers. This study aimed to compare the costs associated with the carrier screening and prevention program versus a no-screening (treatment-only) scenario.
Materials and methods: A cost comparison model was developed using data from the Turkish Statistical Institute, the Ministry of Health, and the Social Security Institution. The annual costs of SMA treatment (with nusinersen and …
Contribution Of Adenosine A2a Receptor Agonist And Antagonist On Ovarian Ischemia/Reperfusion Injury In Rats, Azad Mammadov, Abdullah Tuncay Demi̇ryürek, Ahmet Saracaloğlu, Cahi̇t Demi̇rkiran, İsmai̇l Tuncer Deği̇m, Ömer Eronat, Şeni̇z Demi̇ryürek
Contribution Of Adenosine A2a Receptor Agonist And Antagonist On Ovarian Ischemia/Reperfusion Injury In Rats, Azad Mammadov, Abdullah Tuncay Demi̇ryürek, Ahmet Saracaloğlu, Cahi̇t Demi̇rkiran, İsmai̇l Tuncer Deği̇m, Ömer Eronat, Şeni̇z Demi̇ryürek
Turkish Journal of Medical Sciences
Background/aim: To determine the effects of an A2A receptor agonist regadenoson, an A2A receptor antagonist istradefylline, and istradefylline nanosuspension on ovarian ischemia/reperfusion (I/R) injury in rats.
Materials and methods: A total of 80 female rats were divided into 10 groups: sham, ovarian I/R, blank nanosuspension + ovarian I/R, regadenoson (3 μg/kg) + ovarian I/R, regadenoson (30 μg/kg) + ovarian I/R, istradefylline (0.3 mg/kg) + ovarian I/R, istradefylline (3 mg/kg) + ovarian I/R, istradefylline-loaded nanosuspension (3 mg/kg) + ovarian I/R, istradefylline (3 mg/kg) + regadenoson (30 μg/kg) + ovarian I/R, and istradefylline-loaded nanosuspension (3 mg/kg) + regadenoson (30 μg/kg) + ovarian …
Stocks And Shocks: Assessing The Relative Roles Of Public And Private Inventories In Buffering Rice Price Volatility In The Philippines, Bernhard Dalheimer, Kenneth Foster, Gerald E. Shively, Valerien O. Pede, Dela-Dem Doe Fiankor, Jacob Ricker-Gilbert, Pratibha Bist
Stocks And Shocks: Assessing The Relative Roles Of Public And Private Inventories In Buffering Rice Price Volatility In The Philippines, Bernhard Dalheimer, Kenneth Foster, Gerald E. Shively, Valerien O. Pede, Dela-Dem Doe Fiankor, Jacob Ricker-Gilbert, Pratibha Bist
Department of Agricultural Economics Faculty Publications
Public stockholding of food is politically contentious and economically challenging. Although private stocks are generally understood to be more efficient than public stocks at providing a reliable buffer against production shortfalls, private stocks often fail to stabilize prices during extreme food market shocks. Moreover, maintaining large public stock programs in which the government acts as the buyer or seller of last resort, can be very costly. This paper analyzes the recent historical success of public and private rice stocks in stabilizing domestic rice prices in the Philippines, the world’s largest net importer of rice. Relying on competitive storage theory and …