Digital Commons Network^™

Preparation, Characterization, And Antimicrobial Evaluation Of A Cefepime Derivative With Divalent Transition Metals, Zahraa A. Jaber, Israa H. Ibraheem, Sahar S. Hassan

Baghdad Science Journal

The Schiff base ligand (L)- 1-((7-((Z), was recently synthesized 2–(2-((Z)–5,5-diethyl2-(methoxyimino)acetamido)-2-(methoxycarbonyl)-2,6-dioxotetrahydropyrimidin-4(1H)-ylideneamino) thiazol-4-yl8-oxo-5-thia , the next mineral ions, Ni²⁺, Cu²⁺, Zn²⁺, and Co²⁺, are permitted to react with 1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-methylpyrrolidinium, leading to the formation of new metal complexes with distinct geometric shapes. By detecting the shifting in the azomethines band and the appearance of M-N and M-O bands, FT-IR confirmed the occurrence of coordination through N of azobenzene and two O atoms of beta lactam and ester, indicating the development of Schiff base complexes as well as the original Schiff base. Additionally, we can use …

Synthesis, Characterization And Photodegradation Study Of Titanium Dioxide Nanoparticles Mediated Using Melon Peel Extract, Mohamed Abdelkalik Hussain, Wadhah Naji Al Sieadi

Baghdad Science Journal

The importance of nanotechnology in protecting the environment is represented in multiple applications, including, for example, the green synthesis of nanoparticles (NPs), using the remains of plant parts, as well as photolysis application that used semiconductors NPs which showed a clear effect in treating water from organic pollutants, this study combines these two applications, in terms of green synthesis of titanium dioxide nanoparticles (TiO₂NPs) using melon peel (Cucumis melo L.) in sol-gel method, as well as, the photodegradation of methylene blue dye (MB) by using a new irradiation photoreactor device which has designed and implemented for …

Synthesis, Spectroscopic Characterization, And Photostability Studies Of A New Ligand Derivative Of 4-Bromobenzaldehyde And Its Metal Complexes, Enass J. Waheed, Ali Mudher Abdulkareem, Ibtisam Khalifa Jassim

Baghdad Science Journal

The new Schiff base ligand (L_B) was synthesized by reacting precursor (P) with 4-bromobenzaldehyde. This ligand formed three new complexes: [Pd(L_B)(H₂O)₂]Cl₂ (square planar) and [M(L_B)(H₂O)₂Cl₂].mCl₂ (octahedral), where m=0 for Co⁺² and 1 for Pt⁺⁴, upon reaction with the respective metal ions. Characterization of the ligand (L_B) and its metal complexes involved various techniques including ¹H- and ¹³C-NMR, FT-IR, UV-Vis spectroscopy, magnetic susceptibility measurements, CHNS analysis, and molar conductivity. The photo-stabilization of polymers aims to mitigate …

Meeting Specifications Of Sapo-34 Molecular Sieve With Multi-Templates For Mto Reaction: Kinetic And Experimental Study, Mazin Jasim Mohammed, Najwa Saber Majeed

Baghdad Science Journal

Light olefins become are important products for polymeric and petrochemical industries. Producing olefins from oil become ineffective due to highly production cost. An alternative method for producing olefins using methanol instead of oil source become an efficient process. SAPO-34 considered as a proper zeolite catalyst used in this field. For this purpose, there were many attempts to prepare it with microwave irradiation using DEA, TEA and MOR as templates. Fixed power of 800 W for 200 min was applied in crystallization step. XRD, BET, SEM, EDX, FTIR and TGA analysis were studied for preparing catalysts. XRD analysis showed that producing …

The Impact Of Vascular Endothelial Growth Factor, Neutrophil Gelatinase-Associated Lipocalin, And Interleukin-38 Food And Air Allergy Patients Following The Pandemic Of Covid-19 In Iraq, Esraa Hameed Khamees, Zaizafoon N. Nasif

Baghdad Science Journal

Allergies are a common health issue where the immune system reacts to substances in the environment that are normally harmless. This study further investigates the effects of vascular endothelial growth factor (VEGF), neutrophil gelatinase-associated lipocalin (NGAL), interleukin-38 (IL-38), immunoglobulin E (IgE), and the neutrophil-lymphocyte ratio (NLR) in these individuals, offering insight into the probable processes behind allergic responses following the pandemic. The study comprised 120 non-vaccinated females with previous COVID-19 infection. Groups included controls and food and air (F&A) allergic patients, with 60 individuals matched for age and gender. Serum levels of IL-38, VEGF, IgE, and NGLA were assessed using …

Investigating Interleukin-19 And Interleukin-33 In Breast Cancer Of Iraqi Women: An Immunohistochemical Study, Fouad Najm Abed, Suhad Saad Mahmood

Baghdad Science Journal

Cytokines are immune elements that have been found as marker either for tumor-promoting or inhibiting effects on breast tumor development, depending evidently on their exact quantities as well as the existence of additional modifying variables. The study aims to evaluate the relationship between breast cancer tissue and the expression level of IL-19 and IL-33. This study includes using breast cancer tissue (30 specimens) and normal breast tissue (20 specimens) to analyze the expression level of IL-19 and IL-30. Using immunohistochemical technique, the results indicated that lL-33 and also IL-19 were strongly elevated in patients with stage II and stage III …

A New Prospective Of Colistin Resistance Profile Of Some Staphylococcus Species Isolated From Iraqi Wound Fractured Foot, Zahraa M. Fadhil, Halah H Al-Haideri

Baghdad Science Journal

Sulbactam belongs to β-lactamase inhibitors that are more commonly used for Gram-negative bacteria than Gram-positive bacteria. In this study, nine different species of Staphylococcus (S. aureus, S. epidermidis, S.hominis, S. lentus, S. pseudintermedius, S. lugdunensis, S. haemolyticus, S. sciuri , and S. warneri. were isolated from wounded-fractured feet of Iraqi patients. The spectrum of activity of sulbactam and colistin against all isolates was evaluated. Surprisingly, among S. aureus isolates, 5 (12) isolates were sensitive to colistin, whereas, all bacterial isolates were completely resistant to sulbactam. Here, our study revealed that combining …

Assessment Of Histopathological Features Of The Placenta And Plasma Level Of Βhcg, Estrogen, And Progesterone In First-Trimester Spontaneous Miscarriage, Russul Hameed Hassan, Mukhtar K. Haba

Baghdad Science Journal

Miscarriage is a distressing complication with many fetal and maternal abnormalities. About 15% of pregnancies end in spontaneous miscarriages, and over 80% of these occur in the first 12 weeks of gestation. This research aims to evaluate the changes in the hormonal status in addition to determining the types and incidences of abnormalities in the decidua and chorionic villi of placentas that have been aborted. The peripheral blood samples were collected from twenty normal pregnant women as a control group and 30 aborted women. The obstetric characteristics results showed that the patients' mean maternal age was 25.73 ± 7.32 years …

Intraspecific Meristic Variation In Gambusia Holbrooki From The Middle East And Its Implications For Stock Structure And Taxonomic Status, Fatema A. Al Fatle, Ana L. Ibaňez, Laith A. Jawad

Baghdad Science Journal

An analysis was conducted on the variation in the counts of seven meristic traits of the eastern mosquito fish, Gambusia holbrooki, using samples collected from ten different sites in the Middle East. These sites are located along the Tigris, Euphrates, and Shatt al-Arab Rivers, spanning across Iraq, Iran,Türkiye, and Syria. The study revealed a northward increase in the average values of these meristic traits, with the highest recorded in Türkiye and the lowest in the southern region of Iraq. The statistical analysis using Boxplots demonstrated that the seven meristic features were distinct across different rivers, with no overlap observed. …

Green Synthesis And Characterization Of Prepared Copper Iodide (Cui) Nanoparticles Using Red Cabbage Extract, A. S. Abd-Alsada, Zainab J. Shanan, Aqel Mashot Jafar

Baghdad Science Journal

Copper iodide nanoparticles, CuI NPs, are one of the promising materials for use in many electronic applications. In this work, transparent CuI nanoparticles were prepared by the green force synthesis, which was done by red cabbage extract used not only as a reduction but also as a capping agent to reduce the toxicity in the preparation of CuI nanostructures. The structural properties were investigated by the X-ray diffraction analysis technique, XRD. The X-ray analysis shows the structure has a polycrystalline nature with a cubic phase and appears to have a preferential orientation direction along the (111) plane. Atomic force microscopy …

Relatively Prime Detour Domination Number Of Switching Certain Special Graphs, C. Jayasekaran, L. G. Binoja

Baghdad Science Journal

A set S ⊆ V is said to be a relatively prime detour dominating set of a graph G if it has at least two members is a detour set and a dominating set for any pair of vertices b and w such that (deg(b), deg(w)) = 1. The lowest cardinality of a relatively prime detour dominating set is indicated by γ_rpdn (G) and defines the lowest cardinality of a relatively prime detour dominating set of order γ_rpdn (G) said to as a γ_rpdn-set of G. If there is no relatively prime detour dominating set, the …

Clinician Tele-Mental Health Attitudes In North American Indigenous Communities, Elleh A. Driscoll, Justin Douglas Mcdonald

Journal of Indigenous Research

This study examined mental health clinicians (n=104) serving North American Indigenous clients and how tele-mental health (TMH) factors during and after the COVID-19 pandemic impacted future willingness to continue TMH. Results indicated predictors of future TMH usage were not statistically significant due to the high baseline of willingness to utilize TMH, regardless of factors. The goal of this study was to investigate awareness of clinician attitudes of TMH and promote continued research and training for tele-mental health care with Indigenous populations.

Influence Of Film Formation Kinetics On The Dispersion Of Colloidal Quantum Dots In Organic Small Molecule Matrices, Rachel C. Kilbride, Michael P. Weir, James Xiao, Simon A. Dowland, Jurjen F. Winkel, John E. Anthony, Akshay Rao, Richard A.L. Jones, Anthony J. Ryan, Daniel T.W. Toolan

Chemistry Faculty Publications

Improving the dispersion of colloidal quantum dots (QDs) within organic semiconductor (OSC) matrices remains critical for advancing hybrid nanocomposite optoelectronic technologies. This study investigates how film-deposition kinetics influence the morphology of TIPS-tetracene (TIPS-Tc):PbS QD blends, comparing spin-coating and blade coating for QDs ligated with either native oleic acid (OA) or a matched carboxylic acid functionalised tetracene analogue (TET-CA). Films spun-cast at low spin speeds form highly crystalline TIPS-Tc domains with highly aggregated QDs. Increased spin speed induces a deeper solvent quench, driving rapid TIPS-Tc nucleation while kinetically arresting QD diffusion, which improves QD dispersion within the crystalline matrix. TIPS-Tc:PbS-OA blends …

Vol. 70, No. 7 (February 23, 2026)

Indiana Law Annotated

No abstract provided.

Quenching-Based Electrochemiluminescence Detection Of Chlorpyrifos Using A Portable Sensor Platform, Emre Dokuzparmak

Turkish Journal of Biology

Background/aim: Chlorpyrifos (CPF) is an organophosphate pesticide extensively used in agriculture, posing significant threats to human health due to its neurotoxic effects. Its presence in food products has raised considerable public health concerns, necessitating the development of rapid, sensitive, and reliable detection methods. This study aims to design and validate an electrochemiluminescence (ECL) sensor platform operating via a quenching-based mechanism to enable ultrasensitive detection of CPF in food matrices.

Materials and methods: The sensing strategy exploits the coreactant mechanism between 2-(dibutylamino)ethanol (DBAE) and [Ru(bpy)₃]²+ (tris(2,2′-bipyridyl)ruthenium(II)), wherein CPF suppresses the ECL emission by interfering with the excited-state electron transfer pathway. The …

Investigation Of Antimicrobial Synergism Of Actinomycin Derivatives From Streptomyces Parvus 35m1 Against Escherichia Coli Atcc 25922, Özge Can, Mustafa Ünver Kurt, Meli̇s Küçüksolak, Ataç Uzel, Erdal Bedi̇r

Turkish Journal of Biology

Background/aim: Limited drug development and increased antibiotic tolerance among Gram-negative bacteria have led researchers to consider combination therapy. Actinomycin derivatives, particularly actinomycin D, exhibit a wide range of bioactivities, including antibacterial effects. However, actinomycin D is less effective against Gram-negative pathogens. Therefore, it is essential to demonstrate the synergy of actinomycin D and its derivatives with clinically known antibiotics against Escherichia coli ATCC 25922 and investigate the effects on cellular morphology.

Materials and methods: Streptomyces parvus 35M1 isolated from coastal sediment in İzmir/Türkiye was identified via genome sequencing. Large-scale (30 L) fermentation followed by chromatographic purification yielded compounds 1 (actinomycin …

Transcriptomic Identification And Developmental Mapping Of Nrg3b Expression In Zebrafish, Elham Tarahomi, Nuray Soğünmez Erdoğan

Turkish Journal of Biology

Background/aim: Neuregulin 3 (NRG3) is an epidermal growth factor-like ligand that is involved in neuronal circuit formation in mammals. However, the expression profile of its zebrafish ortholog, nrg3b, remains poorly defined. The transcriptomic analyses of zebrafish sco-spondin mutants, which display alterations in their neurodevelopmental pathways, have indicated potential dysregulation of Nrg3b. Guided by these insights, this study aimed to characterize the temporal and spatial expression patterns of nrg3b in vivo in embryonic and adult zebrafish.

Materials and methods: Publicly available RNA-seq data from heterozygous and maternal-zygotic zebrafish sco-spondin mutants at 5, 15, and 30 days postfertilization (dpf) were analyzed to …

Cover And Contents

Turkish Journal of Biology

No abstract provided.

Biological Evaluation Of Novel 6,9-Disubstituted Purine Analogues In High-Grade Serous Ovarian Cancer Cell Lines, Duygu Altiparmak, Deren Demi̇rel Yavuz, Pinar Kul Karadeni̇zli̇, İrem Durmaz Şahi̇n, Meral Tunçbi̇lek

Turkish Journal of Biology

Background/aim: High-grade serous ovarian cancer (HGSOC) remains one of the most aggressive forms of ovarian malignancy and frequently shows resistance to conventional therapies. This study aimed to synthesize a novel series of purine analogues, 6-[(4-substituted benzyl amine)/(4-substituted aniline)]-9-cyclopentyl purines, and evaluate their anticancer efficacy against HGSOC cell lines.

Materials and methods: We assessed the biological effects of the synthesized purine analogues on the OVCAR3, OVSAHO, and KURAMOCHI HGSOC cell lines using the sulforhodamine B assay. To investigate the mechanism of action, we conducted flow cytometry and western blot analyses, focusing on DNA replication and apoptosis.

Results: Among the tested compounds, …

Crow's Nest, February 23, 2026, Crow's Nest Staff

Crow's Nest

The February 23, 2026 issue of Crow's Nest.

Chimes: February 23, 2026, Calvin University

Chimes

A vibrant tapestry of cultures: Rangeela celebrates 30 years by Ava Roush & Ellerry Johnson

Puentes: Students building bridges amidst immigration concerns by Jorie Cho

Late Night Era's Concert: The end of an era by Ashley Hamons

Cave Night kickoff hosts local artists by Alec DeYoung

Composting streamlined and expanded to all underclassmen dorms by McKenna Wilkinson

Let's talk about sec: Calvin sexuality series confronts purity culture by Sarah Sparling

Scaling rock walls and studying Scripture by Ella Vanden Berg

Economic Evaluation Of Perioperative Pembrolizumab Plus Standard Of Care As Treatment For Resectable Locally Advanced Head And Neck Squamous Cell Carcinoma In The United States, Feng Qian, Arielle G Bensimon, Anjela Tzontcheva, Kimberly Benjamin, Ravindra Uppaluri, Douglas Adkins, Geoffrey Johnson, Catherine Fernan, Dandan Zheng, Yuexin Tang, Biruk Chafamo, Dominic Muston

2020-Current year OA Pubs

AIMS: In the phase 3 KEYNOTE-689 trial (NCT03765918) among patients with resectable locally advanced head and neck squamous cell carcinoma (LA HNSCC), perioperative pembrolizumab (pembrolizumab before surgery, then continued with standard-of-care [SOC] radiotherapy +/- cisplatin after surgery followed by pembrolizumab alone) significantly prolonged event-free survival vs. SOC alone, both in the intention-to-treat population and PD-L1 combined positive score (CPS) ≥1 subgroup. Perioperative pembrolizumab + SOC received Food and Drug Administration approval in June 2025 for resectable LA HNSCC expressing PD-L1 (CPS ≥ 1). The present study evaluated the cost-effectiveness of perioperative pembrolizumab + SOC versus SOC in this indication, from …

Role Of Piezo1 Channels Expressed In Pvn In Regulating Sympathetic Nerve Activity And Arterial Blood Pressure In Rats, Yue Chen, Wei Guo, Jichun Wang, Min Wang, Yuying Yang, Gregory Miodonski, Enshe Jiang, Qing Hui Chen, Yi Yang, Renjun Wang

Michigan Tech Publications

Mechanosensitive Piezo1 channels participate in regulating pain sensitivity, insulin secretion, and vascular tension; however, their expression in the autonomic paraventricular nucleus (PVN) and role in modulating sympathetic outflow and cardiovascular function remain unstudied. In this study, unilateral PVN microinjection of the Piezo1 channel blocker Dooku1 (0.1, 1, 10, 100, and 200 pmol) administered to anesthetized male rats increased renal sympathetic nerve activity (RSNA) and mean artery pressure (MAP) in a dose-dependent manner, with maximum increases of 93 ± 30% (p < 0.0001) and 21 ± 5 mmHg (p < 0.0001), respectively, elicited by Dooku1 at 100 pmol. Similarly, PVN microinjection of the peptide Piezo1 channel blocker GsMTx4 (1 nmol) significantly increased RSNA (p < 0.001) and MAP (p < 0.0001). Conversely, PVN-microinjected Piezo1 channel activators Yoda1 (5 nmol) and Jedi2 (5 nmol) did not significantly alter RSNA or MAP. Western blot and qRT-PCR analyses of the hypothalamic PVN showed abundant Piezo1 mRNA and protein expression. Immunofluorescence detection showed that Piezo1 was expressed in pre-sympathetic PVN neurons with axons projecting to the rostral ventrolateral medulla. We conclude that Piezo1 channels expressed in the autonomic PVN neurons play an important role in regulating sympathetic outflow and cardiovascular function.

Digital Competence Of Primary School Teachers In Andalusia (Spain): A Multidimensional Analysis Based On Self-Perceptions, Francisco Ábalos-Aguilera, Luis M. Romero-Rodríguez, Bárbara Mercedes Castillo Abdul Hadi

Artículos científicos

This study analyzes the self-perception of digital teaching competence (DTC) among primary education teachers in Andalusia, using an instrument based on the European DigCompEdu framework. Data were collected through a self-administered online questionnaire applied to a sample of 416 primary education teachers working in Andalusia. The study employed a mixed-methods design, combining quantitative analyses (descriptive, correlational, and comparative) with qualitative analysis of open-ended responses. Employing a mixed-methods approach, the research assesses teachers’ competence levels and examines differences according to professional experience, school ownership, teaching specialization, and territorial distribution. Results indicate that most teachers perceive themselves at intermediate levels of digital …

The Secret Garden: Staff Caring For Staff, Erin Quinlan, Jennifer Schlebusch

Creating Healthy Work Environments (CHWE)

Healthcare workers provide for others in thoughtful, therapeutic ways, which becomes problematic if their mental and emotional resources are depleted. When healthcare workers experience a self-care deficit, their well-being and patient care are compromised. Recent factors contributing to staff stress include the impact of COVID-19 and the Pediatric Behavioral Health Crisis. An identified need to improve staff well-being was visible. The purpose of this quality improvement project, using the Plan-Do-Study-Act methodology, was to develop and implement the Secret Garden to improve the health of the work environment. The Secret Garden is a staff-only respite space, operationalized and managed to support …

The Echo: February 23, 2026, Taylor University

2025-2026 (Volume 113)

No abstract provided.

Experienced Nurses: Improving Retention By Implementation Strategies Found In Research And Those Applied In Practice, Hemilla Raju Matta

Creating Healthy Work Environments (CHWE)

Background & Purpose: The lack of literature focused on retention of experienced nurses reflects the need for more research in this area to help develop retention strategies and decrease turnover. Literature notes nurses want a safe work place, collegial relationships, supportive leadership and organization, and professional development. The purpose of this quality improvement project was to evaluate the effectiveness of a 12-week educational intervention aimed at professional development.

Methods: The quality improvement project was implemented at a community teaching medical center with outpatient services, located on the east coast post IRB approval. A pre/post educational interventional design method …

A New Nurse’S Journey: How To Increase Retention By Providing The Resiliency Tools Nurses Need, Jocelyn E. Marx, Sara Humeny

Creating Healthy Work Environments (CHWE)

In a recent study, 68% of nurses put their patient's health, safety, and wellness before their own (Linton, M. & Koonmen, J. 2020). This presentation will take you on a journey beginning from the minute a nurse starts in our organization. We believe nurses caring for themselves so they can care for others is a priority. New nurses begin to learn on their very first day of employment at our network how self-care and well-being are a part of our nursing mission, vision, and philosophy, as supported by the chosen nurse theorist Jean Watson. It is encouraged for nurse leaders …

Individual And Workplace Environmental Predictors Of Intent To Leave Current Nursing Job, Kathryn Joyce Leep-Lazar

Creating Healthy Work Environments (CHWE)

Background: High rates of registered nurse (RN) turnover in hospitals strain their ability to keep fully staffed. Poor nurse staffing leads to poor patient, nurse, and organizational outcomes (Rae et al., 2021; Shin et al., 2018, 2019). High rates of RN turnover are also costly for healthcare organizations (NSI Nursing Solutions, 2023). While RN turnover rates in US hospitals have increased significantly since the COVID-19 pandemic (22.5% in 2022 compared with 15.9% in 2019), historically, newly licensed RNs have even higher rates of turnover than their more experienced counterparts (Kovner et al., 2016). It is critically important to understand the …

Showpower: A New Paradigm For Community Engagement, Sean Green

Community Engagement

For decades, the dominant paradigm in community engagement, education, and social work has relied heavily on the concept of "empowerment" to address the systemic gaps hindering marginalized populations. However, the etymological and practical applications of empowerment have increasingly devolved into a paternalistic, deficit-based model, implying a directional transfer of authority from a privileged institution to a subjugated community. As recent scholarship confirms, historically marginalized groups—such as first-generation and low-income students—continue to face persistent structural barriers despite decades of these traditional institutional interventions (López et al., 2023). This white paper formally introduces a novel theoretical framework, lexicon, and operational mindset: Showpower. …