Digital Commons Network^™

Investigating Epigenetic Dysregulation Of Long Non-Coding Rnas In Glioblastoma And Glioma Stem Cells, Pujita Kellampalli, Mansi Gandhi, Dhruv Patel, Nehal Pant, Mihika Mishra, Shehr Bano, Aaron Basnyet

Undergraduate Student Symposium

Glioblastoma multiforme (GBM) or Grade IV glioma is a very aggressive form of brain tumor with an overall survival rate of 15 months. The tumor contains glioma stem cells (GSCs) that are resistant to existing therapies. Long non-coding RNAs such as DNA methylation are implicated in epigenetic dysregulation of GBM and GSCs. In this study, we screened lncRNAs with altered DNA methylation in both tumor cells and GSCs compared to normal neural cells using 450K methylation array data. We identified 508 methylation sites (320 lncRNAs) that were either hypermethylated (or gained methylation) or hypomethylated (lost methylation) in GBM and GSCs. …

Creatine In Dementia And The Aging Brain, Dylan Kuni

Undergraduate Student Symposium

Dementia is a syndrome that interferes with cognitive functions and an individual's ability to function independently. Dementia includes several subtypes caused by different neuropathologies, with Alzheimer's disease (AD) being the most common form. AD is characterized by the accumulation of amyloid beta plaques and neurofibrillary tau tangles in the brain, associated with neuroinflammation, oxidative stress, and deficits in energy metabolism. While treatments for AD exist, the efficacy, safety, and cost are a concern, highlighting the need for additional prevention and treatment strategies. This literature review examines the role of creatine in brain health and disease, including AD and related dementias. …

An Analysis Of Jump Performance Using Wearable Devices In Collegiate Volleyball Attacking Players, Caiden Largent

Undergraduate Student Symposium

Vertical jump height in volleyball, a key performance measure, may be assessed in a laboratory and measured on the court. Baseline lab measurements are conducted in a controlled environment using a Vertec, while on the court, measurements utilize VERT wearable devices as these measurements. VERT estimates jump height indirectly through inertial measurements when compared to Vertec testing. The purpose of this study is to analyze jump height performance in collegiate volleyball attacking players. Four National Collegiate Athletic Association Division II female volleyball attackers were assessed across five separate matches. Results showed differences shown between jump heights across sets and matches …

Effects Of Bhb(Beta-Hydroxybutyrate) Of Mood, Memory, And Handgrip, Christianna Needham, Sahanj Joshi, Jairaj Bajaj

Undergraduate Student Symposium

The purpose of this study was to test the effects of acute beta-hydroxybutyrate (BHB) on handgrip, mood states and memory of healthy men and women. The subjects were exercise science students from Nova Southeastern University between 18-22 years of age. Subjects performed Handgrip strength, Profile of Mood States (POMS), and Memtrax the tests prior to consuming BHB, as well as 30 minutes, and 60 minutes post consumption. A total of 136 healthy participants (20.5±1.4 years) were randomized into three groups: D-BHB (n=47), L-BHB (n=46), or placebo (n=43). A Two-Way ANOVA test revealed no significant …

Understanding Ice Age Climate In Buffalo Gap National Grasslands Through Heavy Mineral Analysis, Chancellor Rockwell Marks, Jenna Church

Undergraduate Student Symposium

More information about ice age climate change during Marine Isotope Stage 2 (MIS 2), the last glacial maximum, is known from ice cores and marine sediments than from continental geology. For scientists to construct climate models, they need climate information about continental areas for comparison. Marine and ice sediments are deposited in layers, year after year, with relatively little disturbance after deposition. Changes in isotopic composition of these sediments reflect profound changes in Earth's climate. The equivalent continental sediment record is loess (windblown dust), which is deposited in fine layers without subsequent disturbance. Here, we studied loess to determine paleowind …

Modeling The Binding Of Salinosporamide A (Mzb) To The Human 20s Proteasome For Potential Cancer Treatment, Jayden Ross, Jayant Ari, Audrey Anand, Giezel Medina

Undergraduate Student Symposium

This project aims to model and observe the binding of the drug Marizomib (MZB) and compare its binding affinity other similar drugs to the proteosome using the PDB ID 9HMN and bioinformatics tools. MZB is an anti-cancer drug that was derived from the marine bacterium, Salinosporamide A. Its function is to inhibit the human 20S proteasome from breaking down excess proteins, causing the cell to trigger apoptosis. Additionally, MZB has the ability to cross the blood-brain barrier and utilize three catalytically active amino acid sites. The existing PDB ID (9HMN) of a 20S proteasome with MZB bound was 3D printed. …

Developing New Digital Methods To Study And Improve Eyewitness Testimony, Isabella Ryan, Brianna Munoz, Adam Durnin, Tanya Schrader, Joana Vinagre

Undergraduate Student Symposium

Witnesses play a crucial role in criminal investigations. However, their ability to recall important details is influenced by cognitive processes such as memory. To improve eyewitness testimony, psychologists developed science-based interviewing techniques, such as the Cognitive Interview, which are used by police to elicit accurate accounts. We also created new retrieval strategies, namely the Category Clustering Recall (CCR), which has been implemented by agencies such as the Los Angeles Police Department. However, research supporting the use of these techniques predominantly used the mock-witness paradigm, where participants observed a mock-crime on a two-dimensional (2D) screen and recalled it in a controlled …

American Public Law Revolution, Victoria Frances Nourse

Georgetown Law Faculty Publications and Other Works

The Supreme Court has birthed a public law revolution. This revolution should not be known as a constitutional revolution because it is bigger than constitutional law—it covers statutory and administrative law as well. This revolution has been powered not by social movements, but by an interpretive philosophy known as originalism. Originalism has been deeply misunderstood by its critics. This Article examines three myths about originalism—that it is primarily about history, that it is a traditional theory of adjudication, and that it is democratic. Originalism is a semantic theory, not a theory of history, and it is a theory that privileges …

Corrigendum To “Advanced Techniques In Quartz Wafer Precision Processing: Stealth Dicing Based On Filament-Induced Laser Machining” [Opt. Laser Technol. 171 (2024) 110474] (Optics And Laser Technology (2024) 171, (S0030399223013671), (10.1016/J.Optlastec.2023.110474)), Yun Wang, Yutang Dai, Farhan Mumtaz, Kaiyan Luo

Electrical and Computer Engineering Faculty Research & Creative Works

The authors regret, that the affiliation for author Yun Wang was incomplete. To accurately reflect both the author's academic affiliation and the research platform where the work was conducted. The correct affiliation for Yun Wang is updated as above. The authors would like to apologize for any inconvenience caused.

De Novo Rras2 Pathogenic Variant In A Fetus With Bilateral Radial Ray And Multisystem Anomalies., Nicole R. Legro, Lylach Haizler-Cohen, William Genthe, Victoria Greenberg

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

When Rescue Becomes Reprogramming: Long-Term Cardiovascular Outcomes In Offspring Following Prenatal Steroid Exposure., Selina M. Tucker, Jessica L. Bradshaw

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

Development And Acceptability Of A Patient Decision Aid For People With Degenerative Cervical Myelopathy: An International Mixed-Methods Study, Andrew R. Gamble, David B. Anderson, Marnee J. Mckay, Benjamin M. Davies, Sophie Macpherson, James Van Gelder, Tammy Hoffmann, Kirsten Mccaffery, Samuel X. Stevens, Carlo Ammendolia, Rohil V. Chauhan, Carl M. Zipser, Timothy F. Boerger, Lindsay A. Tetreault, Michael G. Fehlings, Elanor Dustan, Carolyn Nugent, Helen Holmgren, Andreas K. Demetriades, Justin M. Lantz, Rana Dhillon, Chris G. Maher, Joshua R. Zadro

Biomedical Engineering Faculty Research and Publications

Objectives To develop and user-test a patient decision aid for people diagnosed with degenerative cervical myelopathy and who are considering surgery.

Design Mixed-methods study describing the development of a patient decision aid.

Setting A draft decision aid was developed by a multidisciplinary steering group (including study authors with degenerative cervical myelopathy, health professionals and researchers) informed by the best available evidence, authorship consensus and existing patient decision aids.

Participants Patient-participants and health professional-participants who manage people with degenerative cervical myelopathy were recruited through social media and the steering group’s research and practice network. Quantitative questionnaires were used to gather baseline …

A Low-Noise And High-Gain Integrated Photoplethysmography Sensor For Continuous Vital Signs Monitoring, Neethu Mohan

Dissertations

Photoplethysmography (PPG) sensing is an important technology used for measuring health parameters like, heart rate, respiratory rate, blood oxygen saturation, and blood pressure (BP). The PPG sensing is used for individuals who have to periodically monitor their health due to chronic health conditions. The basic requirements of a wearable PPG sensor include non-invasiveness, prolonged battery life, and being userfriendly. These type of sensors have great demand in the healthcare applications and there is a significant rise in the demand of these sensors. The basic objective of these PPG sensors is to make the continuous vital health monitoring easier without the …

Literary Colonization And Locating Avenues Of Subversion In Bobby Flores-Villasis' Suite Bergamasque, Michael Aaron C. Gomez

Akda: The Asian Journal of Literature, Culture, Performance

This paper examines four short stories included in the collection titled Suite Bergamasque, written by multi-awarded Negrense playwright and fictionist Bobby Flores-Villasis. A materialist reading situates Villasis within the canon of Philippine literature in English and analyzes the way his stories formally render the class antagonisms of history through the interconnected narratives of Dumaguete City’s sugar elite. Finally, this paper also contends that the political imagination of Villasis’ work exhorts contemporary Dumaguete writers to critically examine inherited hagiographies in order to describe fully the conditions that have shaped the city into its contemporary formation, particularly the phenomena of gentrification …

Panitikan At Pakikibakang Pesante: Kasaysayan Ng Pakikibaka Para Sa Repormang Agraryo Sa Tatlong Nobela Ni Lazaro Francisco (Literature And Peasant Struggle: History Of Agrarian Reform Struggles In Three Novels Of Lazaro Francisco), Jester Gabriel De Leon

Akda: The Asian Journal of Literature, Culture, Performance

Binasa ng papel na ito ang tatlong nobela ng Pambansang Alagad ng Sining sa Panitikan na si Lazaro Francisco na Ama (1929), Maganda Pa ang Daigdig (1955), at Daluyong (1962), upang ipatampok ang kasaysayan ng pakikibaka repormang agraryo buhat sa iba pang mga tunggalian na binunga ng nagbabanggaang interes ng mga magbubukid at panginoong maylupa sa isang lipunang malapyudal sang-ayon sa pagsusuring Maoismo. Matapat na isiniwalat ng mga akda ni Francisco ang kalagayan ng magbubukid sa rurok ng malapyudal na pananamantala mula sa panahon ng pananakop ng Estado Unidos hanggang sa panunungkulan ng mga burukrata-kapitalista matapos ang Ikalawang Digmaang Pandaigdig. …

Development Of Holographic Recording Techniques For Optical Couplers Designed For Solar Collection From Windows, Dipanjan Chakraborty

Doctoral

The main purpose of this research is to explore volume holographic optical couplers and investigate their potential for use as solar collectors in glass building structures. Such couplers are from the family of volume holographic optical elements (VHOEs) and their primary function is to re-direct the incident light so that it is trapped by Total Internal Reflection (TIR). They have been proposed for different waveguiding applications such as solar collection, head-up displays, and optical communication. Since the Sun is a non-stationary light source, often at a high altitude, couplers designed for non-normal incidence are crucial.

Ultimately, this work will address …

Afit Librarian Newsletter : Check It Out (Second Quarter 2026), D'Azzo Research Library, Air Force Institute Of Technology

AFIT Library Knowledge Base

In this issue:

• Interview with a Featured Library Advocate, Dr. William Cunningham, AFIT/ENS
• Library Display about “Inventing Flight”
• New Librarian: Catherine Stahl
• Staff Book Picks for Spring Reading

Modeling The Extracellular Matrix-Like Retinal Protein Pikachurin And Its Binding To Α-Dystroglycan And Gpcr (Gpr179), Mohit Belur, Khushi Raval, Riya Chelagiri, Rani Mehta

Undergraduate Student Symposium

Pikachurin is an extracellular matrix scaffold protein that links photoreceptor and ON-bipolar cell synapses by bridging the presynaptic dystroglycan complex and the postsynaptic receptor GPR179, ensuring precise synaptic alignment required for vision. Although its role in dystroglycanopathy associated visual phenotypes is well recognized, there is no published structural model showing how pikachurin engages α-dystroglycan or how this may influence GPCR linked synaptic signaling. This study computationally modeled full length Pikachurin using the complete nucleic acid sequence and available Protein Data Bank structures, integrating Jmol, AlphaFold, and literature-based analysis to predict domain organization, Ca²⁺-binding motifs, and glycan interaction sites …

Using X-Ray Crystallography To Inform Foldamer Drug Design, Isabella Garcia

Undergraduate Student Symposium

Foldamers are synthetic peptide oligomers that fold into well-defined three-dimensional structures, such as alpha-helices and beta-sheets. The goal of this project is to discover the solid-state confirmation of beta-amino acid foldamers that have potential as therapeutic molecules. This research represents an interdisciplinary collaboration between KAIST, a research university in South Korea, and NSU. We solved the single-crystal X-ray structures of two foldamers and then visualized their secondary structures and intermolecular contacts using Mercury. The first foldamer crystallized in the space group P2₁2₁2 and demonstrated a continuous alpha-helical secondary structure, with the residue side chains evenly distributed …

A Compendium Of Sound-Symbol Correspondences In English: More Revelations About The Challenge Of Teaching, Learning, And Applying Phonics, David Reinking, Sharon L. Reinking

Publications

In 2022, we published an article in The Journal of Reading Recovery entitled, “Why phonics (in English) is so difficult to teach, learn, and apply: What caregivers and teach- ers need to know” (Reinking & Reinking, 2022) The article outlined the unique challenges of mastering the diverse, irregular correspon- dences between letters and sounds (phonics) in English compared to the regularity of many other alphabetic languages We provided examples and explained how the complexity of English spelling creates and amplifies difficulties in teaching, learning, and applying phonics Our purpose was not to question the importance and viabil- ity of teaching …

Global Epidemiology Of Cephalopina Titillator Infestation In Camels: A Systematic Review And Meta-Analysis (1980–2025), Temesgen Mohammed, Aboma Zewude, Tsegaye Shamebo, Layaly Hamdan, Atef Oreiby, Hazim O. Khalifa, Gobena Ameni, Bojan Gajic

All Works

Background – Cephalopina titillator (C. titillator) is the causative agent of camel nasopharyngeal myiasis and is widespread in camel-rearing regions worldwide, causing impaired health, reduced productivity, and economic losses. However, despite the veterinary importance of C. titillator, global epidemiological evidence remains limited and fragmented, and no comprehensive synthesis of prevalence data across camel-rearing regions has previously been conducted. The objective of this review was to estimate the global pooled prevalence of C. titillator infestation in camels. In addition, subgroup analyses were made to assess the effect of camel species, geographic region, and study period on the pooled prevalence of C. …

Framing Emirati Womanhood: Heritage, Modernity, And Soft Power In Tourism Discourse, Valerie Priscilla Goby

All Works

This paper examines how Emirati womanhood is framed within the tourism discourse of the United Arab Emirates, analysing how gendered representation operates as both a cultural and political instrument in nation branding. Drawing on framing theory and informed by feminist perspectives on tourism and media representation, this study explores the visual and textual portrayal of women on official online platforms, including Visit Dubai, Visit Abu Dhabi, Emirates Airlines, and the UAE Ministry of Culture and Youth. These materials constitute a state-sanctioned narrative of national identity that integrates cultural heritage with modernity. Through qualitative framing analysis, four recurrent interpretive frames were …

Navigating Inclusive Education In The United Arab Emirates: Perspectives From School Leaders And Teachers, Daisy Loyd, Rhoda Myra Garces-Bacsal, Zachary Walker, Najwa Mohamed Alhosani, Hala Elhoweris, Osha Almuhairy, Ahmed Mohamed, Rachel Alison Takriti, Sana Butti Al Maktoum, Amani Mohamed, Hamdah Jibar Alhashmi

All Works

Inclusive education in the United Arab Emirates (UAE) has been promoted through ambitious policies. These have included a mandated change in nomenclature alongside strengthening the infrastructure and professional development to support inclusive education in mainstream schools. Perspectives from school leaders and teachers across the country about these changes and their implementation have not been captured. This research used a qualitative methodology to explore school leaders' and teachers' perspectives of inclusive education policy and practice. Participants included 22 school leaders and 57 teachers from public and private schools across the seven Emirates of the UAE. Data were collected through group and …

A Critical Narrative Review Appraisal Of The 2025–2030 Dietary Guidelines: Scientific Strengths, Conceptual Gaps, And Overlooked Dimensions Of Sustainability And Health Equity, Dimitrios Papandreou, Azza Alsuwaidi, Zainab Taha, Constantinos Giaginis, Georgios K. Vasios, Eleni P. Andreou

All Works

The 2025–2030 Dietary Guidelines introduce an important shift in public health nutrition, emphasizing minimally processed foods, higher protein intake, greater inclusion of full-fat dairy, and a food-based advice centered on “real food” consumption. While several of these recommendations align with accumulating evidence, particularly the discouragement of ultra-processed foods and added sugars, substantial concerns remain regarding their internal coherence, population-level applicability, risk of misinterpretation, as well as environmental footprint. This critical narrative review evaluates whether the scope, emphasis, and framing of the new guideline components are proportionate to the strength, consistency, and context of the underlying evidence. Using a novel framework …

Rethinking Behavior - Spring 2026, Midwest Symposium For Leadership In Behavior Disorders

ReThinking Behavior Magazine

A magazine for professionals serving children and youth with behavioral needs.

Spring 2026, Volume 9, Issue 3

Book Review: Emplacing Globalisation: Contextualising Mission In Settings Of People, Places And Processes By John Cheong And Jonathan Ro, David H. Campbell

Great Commission Research Journal

No abstract provided.

Book Review: Game Of Pulpits: The 7 Voices Vying For The Kingdom - Who Will Win & Why By Gary Comer, Lavern Brown

Great Commission Research Journal

No abstract provided.

Book Review: The American Religious Landscape By Ryan Burge, Derek Maxson

Great Commission Research Journal

No abstract provided.

About The Great Commission Research Network Spring 2026, David R. Dunaetz

Great Commission Research Journal

No abstract provided.

The Effectiveness Of The Educational Program “Istedamah” (Sustainability) Based On Green School Principles In Shaping Basic Education Students’ Perceptions Of Sustainable Development Dimensions And Their Practices In Achieving Carbon Neutrality In The School Environment In The Sultanate Of Oman, Huda Mubarak Al Dayri, Abdullah. K. Ambusaidi

Journal of Educational and Psychological Studies

The study aimed to identify the effectiveness of “ Istedamah” educational programme, which is based on green school principals, in promoting the perceptions of sustainable development dimensions and their practices related carbon neutrality among basic education students in the Sultanate of Oman. The study used quasi-experimental approach based on one group pre- and post -test design. The sample consisted of 106 male and female students selected randomly from schools that apply green school project. Two tools were used to gather data: A scale of students’ perceptions of the dimensions of sustainable development, (consisted of 26 statements) and practices for achieving …