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Appendiceal Intussusception Due To Endometriosis: A Case Report, Camryn Butera, Taylor Bronson, Justin Spatar, Christine Holloway Apr 2026

Appendiceal Intussusception Due To Endometriosis: A Case Report, Camryn Butera, Taylor Bronson, Justin Spatar, Christine Holloway

Research Day

The rate of implantation of endometrial tissue onto the appendix varies greatly within the literature with appendiceal intussusception being a rare clinical presentation in this small subset of patients. Here we discuss a case of appendiceal endometriosis with robotic partial cecectomy and appendectomy. This report describes our experience with appendiceal cecal intussusception. We report a case of appendiceal endometriosis causing intussusception. It is important to consider endometriosis as a cause of appendiceal intussusception in the differential diagnosis of females presenting with the common chief complaint of abdominal pain, especially in the setting of prior gynecological surgeries.


Medical Student Advocate–Community Health Worker Collaboration To Improve Colorectal Cancer Screening Rates, Christopher J. Antoniello, Juliana N. Heppard, Vanessa I. Saylor Apr 2026

Medical Student Advocate–Community Health Worker Collaboration To Improve Colorectal Cancer Screening Rates, Christopher J. Antoniello, Juliana N. Heppard, Vanessa I. Saylor

Research Day

INTRODUCTION:

Lankenau Medical Center launched the Medical Student Health Advocates (MSA) Program in 2012 to address the impact of socioeconomic status and social determinants on health outcomes. Data shows that publicly insured patients are generally more disadvantaged in these areas compared to commercially insured patients. The Colorectal Cancer Screening Initiative (CCSI), a partnership between MSAs and the Department of Health Equity’s Community Health Worker (CHW) team, aims to improve colorectal cancer (CRC) screening rates among Medicaid and dual Medicare/Medicaid patients, narrowing the gap between commercially insured and publicly insured patient populations.

METHODS:

Through weekly calls, CHWs and MSAs provide patients …


Effects Of Meditation On Blood Pressure, Ian T. Mcdonald, Chanelle Zorrilla Arias, Kristen Berry Apr 2026

Effects Of Meditation On Blood Pressure, Ian T. Mcdonald, Chanelle Zorrilla Arias, Kristen Berry

Research Day

Introduction:

Hypertension is a major cardiovascular risk factor in the United States and is associated with serious complications, including myocardial infarction, stroke, and kidney failure, and other outcomes resulting from destroyed vessels. Although antihypertensive medications are widely used to manage hypertension, treatment is often limited by medication cost, polypharmacy, and poor adherence. Medication nonadherence remains a significant barrier to effective blood pressure control and is associated with adverse health outcomes, including increased mortality. Meditation, a stress-reduction intervention, may represent a feasible adjunctive therapy for the management of hypertension. We hypothesize that introducing people to meditation and encouraging them to continue …


Implementing Firearm Safe Storage And Screening Handouts For Older Individuals Into Primary Care Practice, Rebecca Delp, Erik E. Langenau, Ilene Warner-Maron Apr 2026

Implementing Firearm Safe Storage And Screening Handouts For Older Individuals Into Primary Care Practice, Rebecca Delp, Erik E. Langenau, Ilene Warner-Maron

Research Day

Introduction

Older adults have the highest rates of firearm-related suicide in the United States, with firearms accounting for approximately 70% of suicides in this population (Price et al). Risk is particularly elevated among older men and veterans (Mcintosh et al). Despite this, firearm safety counseling remains uncommon; only 3.7% of older adults report discussing firearm safety with a healthcare provider (Carter et al). This exposes an important opportunity to address firearm safety, mental health, and suicide prevention in the primary care setting, while providing resources for access to firearm safe storage devices.

This project’s aim was to develop and implement …


A Literature Review Of The Correlation Between Faun Tail Nevus Presentation And Spinal Dysraphisms, Zahraa Ibrahem, Feryal Hilmi, Yuna Huh, Mindy Hill Apr 2026

A Literature Review Of The Correlation Between Faun Tail Nevus Presentation And Spinal Dysraphisms, Zahraa Ibrahem, Feryal Hilmi, Yuna Huh, Mindy Hill

Research Day

Faun tail nevus (FTN) is a rare congenital cutaneous finding characterized by a localized tuft of hair over the lower lumbar vertebrae, typically in a midline distribution. Although faun tail nevus can be present without underlying spinal abnormality, it is frequently seen in the presence of underlying occult spinal dysraphism, most commonly spina bifida occulta. The presence and severity of accompanying cutaneous features, such as dense hypertrichosis, midline dimpling, dermal sinus tracts, or visible subcutaneous tracking, may correlate with the extent of underlying spinal pathology. Given this association, spinal imaging with ultrasound in infants or magnetic resonance imaging in older …


The Use Of Tracheal Traction Exercises To Prevent Post-Operative Dysphagia Following Anterior Cervical Discectomy And Fusion, Emily Schmeiser, Elizabeth Gammer, Yasmine Eichbaum, Mitchell K. Ng, Gregorio Baek, Joshua Mathews, Morgan Hitchner, Yulia Lee, William A. Green, Thomas Cha, Mark Kurd, Ian D. Kaye, Jose A. Canseco, Alexander R. Vaccaro, Christopher K. Kepler, Gregory D. Schroeder Apr 2026

The Use Of Tracheal Traction Exercises To Prevent Post-Operative Dysphagia Following Anterior Cervical Discectomy And Fusion, Emily Schmeiser, Elizabeth Gammer, Yasmine Eichbaum, Mitchell K. Ng, Gregorio Baek, Joshua Mathews, Morgan Hitchner, Yulia Lee, William A. Green, Thomas Cha, Mark Kurd, Ian D. Kaye, Jose A. Canseco, Alexander R. Vaccaro, Christopher K. Kepler, Gregory D. Schroeder

Research Day

Introduction: Dysphagia is a commonly reported complication following anterior cervical disc fusion (ACDF). Some of the risk factors that increase dysphagia incidence include elevated BMI, smoking, female gender, and diabetes mellitus type 2. Treatment with methylprednisone administration and manipulation of endotracheal cuff pressures has been correlated with milder dysphagia in the intraoperative and early post-operative period; however, long-term differences between the control and treatment groups have not been statistically significant. Tracheal traction exercises are of emerging interest for treating ACDF patients with dysphagia. The purpose of this systematic review is to explore the outcome of the use of pre-operative tracheal …


Adverse Hematologic Reaction In A 25-Year-Old Female: A Case Of Drug-Induced Cytopenia, Makayla E. Farr, Wenhui Zhu Apr 2026

Adverse Hematologic Reaction In A 25-Year-Old Female: A Case Of Drug-Induced Cytopenia, Makayla E. Farr, Wenhui Zhu

Research Day

INTRODUCTION: Drug-induced cytopenia is a rare but potentially serious hematologic adverse reaction that may present with nonspecific symptoms. This adverse reaction is typically caused by either direct myelotoxicity or immune-mediated destruction. The mechanism by which statins cause cytopenia is not fully understood; however, some studies hypothesize that it may be due to platelet apoptosis or an immune-mediated destruction via the drug’s metabolites triggering an immune response.

In this case, a young female developed cytopenia secondary to pravastatin 20mg. Upon presentation to the emergency department, she reported slurred speech and left upper extremity numbness, followed by facial droop. The physical examination …


A Case Study: Undiagnosed Familial Hypertriglyceridemia Inciting Acute Pancreatitis, Alice Koschella, Rachael Bonitatibus, Raymond Alvarez Apr 2026

A Case Study: Undiagnosed Familial Hypertriglyceridemia Inciting Acute Pancreatitis, Alice Koschella, Rachael Bonitatibus, Raymond Alvarez

Research Day

Background: Familial hyperlipidemia encompasses a group of inherited lipid metabolism disorders characterized by elevated serum cholesterol and/or triglyceride levels. Severe hypertriglyceridemia, particularly levels exceeding 1,000 mg/dL, is a well-established but less common cause of acute pancreatitis (1). Acute pancreatitis is an inflammatory condition of the pancreas most frequently attributed to gallstones or alcohol use; however, hypertriglyceridemia accounts for approximately 1–10% of cases and is associated with increased morbidity when not promptly recognized and treated.

Introduction: Hypertriglyceridemia-induced acute pancreatitis results from excessive circulating triglyceride-rich lipoproteins, leading to free fatty acid release and pancreatic inflammation (2). Young patients without traditional risk factors …


Vaginal Rectopexy For Rectal Prolapse In Advanced Pelvic Organ Prolapse: A Review Of Surgical Strategies, Williams Cheau, Ebony Isagba, Mykala Jackson, Sabirah Smith, Alexandria Neal Apr 2026

Vaginal Rectopexy For Rectal Prolapse In Advanced Pelvic Organ Prolapse: A Review Of Surgical Strategies, Williams Cheau, Ebony Isagba, Mykala Jackson, Sabirah Smith, Alexandria Neal

Research Day

Pelvic organ prolapse (POP) is a common condition in women, frequently involving the anterior or posterior vaginal compartments. While biologic grafts are increasingly used in cystocele repair, their application in rectocele repair remains rare and underreported.

A 61-year-old female presented with fecal incontinence, mixed urinary incontinence, and symptomatic pelvic organ prolapse, including a stage II midline cystocele, rectocele, and suspected rectal prolapse. She was scheduled for anterior and posterior vaginal wall repair.

This case illustrates a novel use of biologic grafting in rectocele repair with concurrent rectal prolapse management. While graft use in anterior repairs is becoming more common, its …


A Hard Pill To Swallow: Management Of Olanzapine-Induced Dysphagia, Anthony Pelache, Alexandria Neal, Alexandra Ortiz, Caleb Rowan Apr 2026

A Hard Pill To Swallow: Management Of Olanzapine-Induced Dysphagia, Anthony Pelache, Alexandria Neal, Alexandra Ortiz, Caleb Rowan

Research Day

Background:

Dysphagia is a concerning but uncommon adverse effect associated with both first- and second-generation antipsychotic (neuroleptic) medications. The U.S. Food and Drug Administration has issued warnings regarding impaired swallowing with neuroleptic use, and multiple studies and case reports have documented its occurrence across various agents. However, dysphagia presenting as an isolated or predominant adverse effect remains rarely described in the literature. The proposed mechanisms remain debated, with hypotheses including extrapyramidal dysfunction affecting oropharyngeal musculature versus anticholinergic-mediated impairment of swallowing reflexes. Regardless of etiology, reported management strategies are consistent and include dose reduction, discontinuation, or switching to an alternative antipsychotic …


Regional Selective Vulnerability To Hypoxic-Ischemic Injury In A Neurodegenerative Brain: A Cadaveric Case Study, Naomi Abraha, Jordan Ahlgren, Sangavi Sriranganathan, Tyrese Claridge-Rogers, Rasheed Agboola, Joshua Owolabi Apr 2026

Regional Selective Vulnerability To Hypoxic-Ischemic Injury In A Neurodegenerative Brain: A Cadaveric Case Study, Naomi Abraha, Jordan Ahlgren, Sangavi Sriranganathan, Tyrese Claridge-Rogers, Rasheed Agboola, Joshua Owolabi

Research Day

Introduction

Senile brain disease is characterized by progressive neurodegeneration, neuronal loss, abnormal protein aggregation, and structural changes within brain tissue that occur with aging. Neurodegenerative disorders, such as Alzheimer’s disease and other forms of dementia, are among the most common age-related neurological conditions and are associated with cognitive decline and widespread pathological changes throughout the brain. These disorders contribute significantly to morbidity in elderly populations and reflect the gradual deterioration of neural tissue.

Acute medical events may further exacerbate neurological damage in individuals with chronic neurodegenerative disease. Cardiopulmonary arrest is defined as the sudden cessation of cardiac and respiratory function, …


Retinal Artery Occlusion Mimicking Giant Cell Arteritis: A Case Report, Zain Ismail, Amaan Ismail, Chris Luz Apr 2026

Retinal Artery Occlusion Mimicking Giant Cell Arteritis: A Case Report, Zain Ismail, Amaan Ismail, Chris Luz

Research Day

Acute monocular vision loss is a medical emergency that requires prompt work-up to identify the cause. The etiologies of vision loss are broad including vascular, inflammatory, thromboembolic, and neural pathologies. Here we present the curious case of a 57-year-old male with a history of HTN, CAD, prior CVA and T2DM who was admitted to the medicine floor for a recurrent transient vision loss in his right eye for the past 18-months. Based on the patients PMH, an immediate differential diagnosis included: Central Retinal Artery Occlusion, Giant Cell Arteritis, Amaurosis Fugax secondary to carotid embolism, and Optic Neuropathy secondary to Diabetic …


Incidental Identification Of A Femoral Arterial Stent And Vascular Closure Devices Within The Common Femoral Arteries: A Cadaveric Case Report, Danait W. Gebreselassie, Nathan Sagasser, Misha Ul-Islam, Jada Daniel, Abeeha Choudhary, Christian Butler, Abigail Blank, Sofia Garcia Apr 2026

Incidental Identification Of A Femoral Arterial Stent And Vascular Closure Devices Within The Common Femoral Arteries: A Cadaveric Case Report, Danait W. Gebreselassie, Nathan Sagasser, Misha Ul-Islam, Jada Daniel, Abeeha Choudhary, Christian Butler, Abigail Blank, Sofia Garcia

Research Day

Introduction: The common femoral artery (CFA) is the most frequently accessed vessel for diagnostic angiography and endovascular interventions due to its superficial location, large caliber, and reliable anatomic landmarks. Ultrasound‑guided access has reduced complication rates, while vascular closure devices (VCDs) are routinely used to achieve hemostasis following catheterization to optimize recovery and allow early patient mobilization. Intraluminal stents and VCDs are both generally safe although they can alter local vascular anatomy. Cadaveric dissection provides a unique opportunity to identify these devices and assess their anatomic impact. During routine dissection of a 68‑year‑old White male donor, bilateral metallic structures were unexpectedly …


A Literary Analysis And Cadaveric Evaluation Of The Medtronic Intellis™ Adaptivestim Spinal Cord Stimulator: Anatomical Correlates And Clinical Implications, Nicholas Auge-Dario, Olivia Peoples, Alexa Staudt, Anika Mittal, Shamar Palmer, Neel Patel, Syed Khalid, Emranul Huq Apr 2026

A Literary Analysis And Cadaveric Evaluation Of The Medtronic Intellis™ Adaptivestim Spinal Cord Stimulator: Anatomical Correlates And Clinical Implications, Nicholas Auge-Dario, Olivia Peoples, Alexa Staudt, Anika Mittal, Shamar Palmer, Neel Patel, Syed Khalid, Emranul Huq

Research Day

Background/Objectives:

The clinical efficacy of spinal cord stimulation (SCS) for chronic neuropathic pain depends on precise epidural lead placement to appropriately target the dorsal columns specific to patient cases. However, anatomical variability within the thoracic spinal canal, such as discrepancies between vertebral levels and spinal cord segments, differences in epidural fat distribution, ligamentum flavum thickness, and spinal cord dimension, may alter the spatial relationship between implanted leads and neural targets. These variations may contribute to inconsistent stimulation coverage and clinical outcomes due to alterations that can be avoided for better patient satisfaction.

Methods:

A focused anatomical and literature-based evaluation, along …


The Effect Of Left Sided Heart Dominant Circulation On Athletic Performance, Reginald D. Dixon, Blessing A. Adeyemo, Paul M. Catalano, Chloe A. Davis, Micheal G. Elkomos, Rachel E. Lippincott, George M. Zakour, Sebastian Egberts Apr 2026

The Effect Of Left Sided Heart Dominant Circulation On Athletic Performance, Reginald D. Dixon, Blessing A. Adeyemo, Paul M. Catalano, Chloe A. Davis, Micheal G. Elkomos, Rachel E. Lippincott, George M. Zakour, Sebastian Egberts

Research Day

Background

Coronary artery dominance is defined as the coronary artery that gives rise to the posterior descending artery (PDA), which supplies the inferior wall of the heart and portions of the interventricular septum. In the majority of individuals, the PDA originates from the right coronary artery, resulting in right coronary dominance. Left coronary dominance, in which the PDA arises from the circumflex branch of the left coronary artery, occurs less frequently and may influence myocardial perfusion patterns and clinical outcomes during coronary artery disease.

Objective

The objective of this report is to describe a case of left coronary artery dominance …


A Cadaveric Analysis Of Chronic Kidney Disease With Preserved Left Ventricular Morphology, Hania Hashmi, Alex Fishel, Justin Laplace, Skylar Keating, Christen York, Dev Desai, Doan Nguyen, Misha Ul-Islam, Rasheed Agboola, Shiv Dhiman Apr 2026

A Cadaveric Analysis Of Chronic Kidney Disease With Preserved Left Ventricular Morphology, Hania Hashmi, Alex Fishel, Justin Laplace, Skylar Keating, Christen York, Dev Desai, Doan Nguyen, Misha Ul-Islam, Rasheed Agboola, Shiv Dhiman

Research Day

Introduction:

A well-established link exists between cardiovascular disease (CVD) and chronic kidney disease (CKD). Reduced kidney function triggers a cascade of hemodynamic changes, including systemic hypertension and inflammatory responses, leading to left ventricular hypertrophy (LVH). In advanced stages of CKD, uremic cardiomyopathy (UC) is implicated in the progression of CKD and LVH. While the progression of CKD to LVH has been investigated, there remains a gap in the literature regarding the mechanisms underlying the preservation of left ventricular architecture and function in the pathogenesis of CKD. This study presents a post-mortem histological analysis of an 82-year-old African American male cadaver …


Splenomegaly And Abnormal Bone Remodeling With Pancytopenia And Myelodysplastic Anemia: A Cadaveric Case Study, Mika Matteo Apr 2026

Splenomegaly And Abnormal Bone Remodeling With Pancytopenia And Myelodysplastic Anemia: A Cadaveric Case Study, Mika Matteo

Research Day

 Introduction: Pancytopenia is a severe reduction in erythrocytes, leukocytes, and platelets, often resulting in anemia and increased susceptibility to infection, and is closely associated with Myelodysplastic syndromes (MDS), a group of bone marrow disorders with ineffective hematopoiesis.

The spleen, an important part of the lymphatic and immune systems, filters circulating blood, removes senescent erythrocytes, and supports immune function. Splenomegaly, pathological enlargement of the spleen, can exacerbate pancytopenia by sequestering and prematurely destroying blood cells.

This study examines the relationship between marrow dysfunction, splenic enlargement, and skeletal remodeling observed during cadaveric dissection to better understand the systemic effects of MDS.

Methods: …


Understanding Doxycycline-Induced Phototoxicity, Setareh Khani, Sydnee Jackson, Darya Khani, Rekha Yesudas Apr 2026

Understanding Doxycycline-Induced Phototoxicity, Setareh Khani, Sydnee Jackson, Darya Khani, Rekha Yesudas

Research Day

Introduction: Doxycycline is a tetracycline-class antibiotic that inhibits bacterial protein synthesis by binding to the 30s ribosomal subunit, thereby preventing bacterial growth. It has a broad spectrum of clinical indications including treatment of Chlamydia infections, Lyme disease, Anthrax, Rickettsia, Atypical pneumonia, Staph aureus, Cholera, Acne vulgaris, and Traveler’s diarrhea, as well as malarial prophylaxis. Although generally well tolerated, effective and affordable, doxycycline is associated with several mild adverse effects like gastrointestinal distress and photosensitivity. One clinically significant adverse reaction is phototoxicity which occurs following exposure to ultraviolet radiation. In doxycycline-induced phototoxicity, the drug absorbs UV light and generates reactive oxygen …


Literature Review: Long-Term Effects Of Circumcised Neonates Vs Uncircumcised Neonates, Jada M. Glenn, Daphne Mlachila Apr 2026

Literature Review: Long-Term Effects Of Circumcised Neonates Vs Uncircumcised Neonates, Jada M. Glenn, Daphne Mlachila

Research Day

INTRODUCTION:

Circumcision is a widely practiced procedure, but as research has progressed, its value beyond a purely cosmetic or cultural purpose has come into question. Outside  of a religious context, circumcision has been popularized by the belief that it has significant medical benefits that justify the permanent removal of the foreskin in a neonate. These benefits include, but are not limited to, a reduction in urinary tract infections, transmission of sexually transmitted diseases, and penile cancer. However, recent studies have shown that these reductions are minimal, especially in countries where AIDS is no longer an epidemic. Other studies have also …


Implications Of Benign Prostatic Hyperplasia And Undiagnosed Seminal Vesiculitis: A Literature Review, Lauren A. Labib, Azmeer Imran, Michael Elkomos, Emranul Huq Apr 2026

Implications Of Benign Prostatic Hyperplasia And Undiagnosed Seminal Vesiculitis: A Literature Review, Lauren A. Labib, Azmeer Imran, Michael Elkomos, Emranul Huq

Research Day

Introduction

Benign prostatic hyperplasia (BPH) is a highly prevalent condition among aging men and a major cause of lower urinary tract symptoms (LUTS). While BPH is extensively studied, inflammatory conditions of adjacent structures, particularly seminal vesiculitis, remain underrecognized. Undiagnosed seminal vesiculitis in patients with BPH may contribute to persistent urogenital symptoms, recurrent infections, fertility impairment, and post-procedural complications. The overlapping symptoms and shared inflammatory pathways between these conditions complicate diagnosis and management. This review evaluates the clinical implications of coexisting BPH and undiagnosed seminal vesiculitis.

Methods

A narrative review of the literature was conducted focusing on studies addressing BPH, seminal …


Correlation Between Gross Pulmonary Pathology And End-Stage Chronic Obstructive Pulmonary Disease, Chloe A. Davis, Blessing A. Adeyemo, Paul M. Catalano, Reginald D. Dixon, Michael G. Elkos, Rachel E. Lippencott, George M. Zakour, Rasheed Agboola, Shiv Dhiman Apr 2026

Correlation Between Gross Pulmonary Pathology And End-Stage Chronic Obstructive Pulmonary Disease, Chloe A. Davis, Blessing A. Adeyemo, Paul M. Catalano, Reginald D. Dixon, Michael G. Elkos, Rachel E. Lippencott, George M. Zakour, Rasheed Agboola, Shiv Dhiman

Research Day

Background: Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder characterized by persistent airflow limitation, chronic airway inflammation, and structural destruction of lung parenchyma. Long-term exposure to inhaled irritants, particularly tobacco smoke and environmental pollutants, contributes to chronic inflammation and remodeling of pulmonary tissue. In advanced stages of COPD, pathological changes such as alveolar destruction, hyperinflation, and particulate matter deposition may be present. While imaging and histopathological studies commonly describe these changes, direct anatomical observation during dissection provides a unique opportunity to correlate disease processes with gross pulmonary morphology.

Objective: To examine and document gross pulmonary abnormalities associated with …


Abdominal Aortic Aneurysm As A Marker Of Systemic Atherosclerosis In A Patient With Prior Coronary Bypass And Fatal Middle Cerebral Artery Stroke: A Cadaveric Case Study, Jordan B. Ahlgren, Azmeer Imran, Rachel K. Ransom, Akosua A. Crumbsy, Lindsey D. Cohen, Angela V. Covington, Mphatso J. Onyekachi, Shiv Dhiman Apr 2026

Abdominal Aortic Aneurysm As A Marker Of Systemic Atherosclerosis In A Patient With Prior Coronary Bypass And Fatal Middle Cerebral Artery Stroke: A Cadaveric Case Study, Jordan B. Ahlgren, Azmeer Imran, Rachel K. Ransom, Akosua A. Crumbsy, Lindsey D. Cohen, Angela V. Covington, Mphatso J. Onyekachi, Shiv Dhiman

Research Day

INTRODUCTION: Abdominal aortic aneurysm (AAA) is frequently associated with systemic atherosclerotic disease and increased risk for cardiovascular morbidity. The development of AAA is attributed to hypertension, smoking tobacco, and other factors such as genetics. Patients with vascular diseases also develop multisystem involvement, including coronary, cerebrovascular, and cardiac conduction abnormalities. The purpose of this case study was to investigate the role artherosclerotic disease played the in the fatal left middle cerebral artery (MCA) ischemic stroke of a 75-year-old male with a visible abdominal aortic aneurysm, history of coronary artery bypass grafting (CABG), and permanent pacemaker implantation.

METHODS: Systematic gross anatomical dissection …


Unique Combination Of Scapula Fracture And Pectoralis Major Tear Sustained During Static Line Airborne Operations: Case Report, Kimberton Porter, Mykala Jackson, Kenneth Nelson, Jeffrey Hoffmann Apr 2026

Unique Combination Of Scapula Fracture And Pectoralis Major Tear Sustained During Static Line Airborne Operations: Case Report, Kimberton Porter, Mykala Jackson, Kenneth Nelson, Jeffrey Hoffmann

Research Day

Scapular fractures are rare and often managed in a non-operative fashion. This report includes a case of a 35 year old active duty male who sustained a critically comminuted scapular body fracture with an isolated pectoralis major tendon tear whilst participating in a static line parachute jump. The patient presented with new onset left shoulder pain, inflammation, and functional loss but did not show any signs of associated systemic trauma. On imaging, there were scapular fragments that were displaced as well as a proximal pectoralis major rupture. Given the severe degree of displacement and the occupational demands of the patient, …


Gross Anatomical Manifestations Of Metastatic Sigmoid Colon Adenocarcinoma Observed During Cadaveric Dissection, Rachel M. Fontaine, Sabrina Mack, Diana Petrucello Apr 2026

Gross Anatomical Manifestations Of Metastatic Sigmoid Colon Adenocarcinoma Observed During Cadaveric Dissection, Rachel M. Fontaine, Sabrina Mack, Diana Petrucello

Research Day

Introduction:

Adenocarcinomas are malignant tumors that originate from mucus-secreting glandular cells within the epithelial layer of the mucosa. The sigmoid colon is a frequent primary site for these tumors, which commonly arise from precancerous adenomatous polyps that gradually become malignant through progressive dysplastic changes. Adenocarcinomas of the sigmoid colon may metastasize through lymphatic or hematogenous pathways to distant organs, resulting in significant structural and functional alterations. The current case highlights extensive morphological changes that can occur with advanced metastatic adenocarcinoma.

Methods:

A 58-year-old African American female with documented metastatic adenocarcinoma of the sigmoid colon was dissected during a routine gross …


Case Report Highlights Disproportionate Health Outcomes Of Rheumatoid Arthritis In Patients Of Lower Socioeconomic Status, Victoria Pfennig, Karen Vega Apr 2026

Case Report Highlights Disproportionate Health Outcomes Of Rheumatoid Arthritis In Patients Of Lower Socioeconomic Status, Victoria Pfennig, Karen Vega

Research Day

Introduction

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that affects the synovial lining of joints and may lead to progressive joint destruction, disability, and premature mortality if inadequately treated. Increasing evidence demonstrates that social determinants of health, particularly socioeconomic status (SES), significantly influence disease outcomes in patients with RA. Studies have shown that individuals of lower SES experience higher disease activity scores, greater physical disability, and poorer quality of life compared with patients of higher SES. Additionally, lower SES has been associated with longer delays between diagnosis and initiation of disease-modifying antirheumatic drugs (DMARDs), contributing to disease progression …


Recognizing Extrapelvic Disease: A Case Of Umbilical Endometriosis Diagnosed At Laparoscopy, Caroline R. Kebberly, Audrey Arona Apr 2026

Recognizing Extrapelvic Disease: A Case Of Umbilical Endometriosis Diagnosed At Laparoscopy, Caroline R. Kebberly, Audrey Arona

Research Day

Background: Extrapelvic endometriosis is defined by the presence of endometrial-like tissue located outside the pelvic cavity and beyond the gynecologic organs. Its true prevalence remains difficult to establish due to limited epidemiologic data, under recognition and frequent diagnostic delay. Umbilical endometriosis represents approximately 30–40% of abdominal wall endometriosis cases and accounts for an estimated 0.5–1.0% of all reported endometriosis diagnoses. Clinical suspicion is typically based on symptomatology, as patients often present with dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility.

Objective: We present a case of umbilical endometriosis, also known as Villar’s nodule, identified during diagnostic laparoscopy performed for suspected pelvic …


Epigenetics Programming Of T2dm Risk In The South Asian Community And Its Implications For Clinical Practice, Arpita Harapanahalli, Shalini Patibandla, Francis Jenney Apr 2026

Epigenetics Programming Of T2dm Risk In The South Asian Community And Its Implications For Clinical Practice, Arpita Harapanahalli, Shalini Patibandla, Francis Jenney

Research Day

Background: Type 2 diabetes mellitus (T2DM) occurs at disproportionately higher rates among South Asian populations compared with other ethnic groups, posing significant challenges for disease risk and clinical management. South Asians are also predisposed to central adiposity, demonstrating greater visceral fat accumulation even at lower body mass index levels, which contributes to increased insulin resistance. From a clinical perspective, understanding these genetic and epigenetic influences is incredibly important for improving prevention and adapting care for South Asian communities.

Objectives: This review aims to examine current evidence on epigenetic mechanisms contributing to T2DM risk in South Asian communities and its implications …


Targeting Dysbiosis: Rebyota As A Novel Strategy For Recurrent Cdi Prevention, Christina Cologer, Mishel Alvarez, Sia Christine, Brooklyn Myers, Kaytlin Pal, Katrina Strand, Vicky Mody, Shashidharamurthy Taval Apr 2026

Targeting Dysbiosis: Rebyota As A Novel Strategy For Recurrent Cdi Prevention, Christina Cologer, Mishel Alvarez, Sia Christine, Brooklyn Myers, Kaytlin Pal, Katrina Strand, Vicky Mody, Shashidharamurthy Taval

Research Day

Clostridioides difficile is a bacterium that colonizes a patient's gastrointestinal tract after the use of systemic antibiotics. This infection, also called CDI, causes severe diarrhea and can be life-threatening. In some patients, CDI recurs, creating a dangerous cycle. Recurrent CDI (rCDI) persists because systemic antibiotics induce dysbiosis, disrupting the gut microbiota’s metabolic functions and compromising the intestinal epithelial barrier. This study was conducted as a literature review evaluating the safety, efficacy, mechanism of action, and clinical use of Rebyota in preventing rCDI. Rebyota is the first FDA-approved (2023) live biotherapeutic designed to restore eubiosis in adult patients after antibiotic treatment. …


Cardiometabolic Risk Factor Burden And Early Cardiovascular Disease Onset Among Asians: Insights From The Nih All Of Us Cohort And Georgia Oasis, Riya S. Patel, Anirudh Veludhandi, Thomas Last Apr 2026

Cardiometabolic Risk Factor Burden And Early Cardiovascular Disease Onset Among Asians: Insights From The Nih All Of Us Cohort And Georgia Oasis, Riya S. Patel, Anirudh Veludhandi, Thomas Last

Research Day

INTRODUCTION: Cardiometabolic risk factors including diabetes, obesity, and smoking are major contributors to cardiovascular disease (CVD), yet the cumulative impact of multiple risk factors on age of onset across cardiovascular phenotypes remains incompletely defined. Cardiovascular risk patterns in Asian populations may differ from those in the general population, and the influence of cumulative cardiometabolic risk burden on early disease remains insufficiently characterized. Understanding how cardiometabolic risk burden influences early cardiovascular disease among Asians may help identify high-risk individuals and guide prevention strategies.

OBJECTIVES: To determine whether increasing cardiometabolic risk factor burden is associated with earlier cardiovascular disease onset among Asians …


Feasibility Of Transcranial Magnetic Stimulation For Treatment-Resistant Depression In Rural Healthcare Settings: A Case Series, Posey Kent, Brandon Krout, Kennedy Johnson, Jodeci Mitchell, Hania Hashmi, Blessing Adeyemo, Ashlee Cook Apr 2026

Feasibility Of Transcranial Magnetic Stimulation For Treatment-Resistant Depression In Rural Healthcare Settings: A Case Series, Posey Kent, Brandon Krout, Kennedy Johnson, Jodeci Mitchell, Hania Hashmi, Blessing Adeyemo, Ashlee Cook

Research Day

Introduction

Major depressive disorder (MDD) is one of the most common mental health disorders world- wide, with up to one-third of patients experiencing treatment-resistant depression despite adequate pharmacologic therapy. Transcranial Magnetic Stimulation (TMS) is an FDA-approved, noninvasive treatment shown to improve depressive symptoms in treatment-resistant depression. However, access to advanced psychiatric interventions remains limited in rural communities due to provider shortages, transportation barriers, and socioeconomic challenges. Despite established efficacy in urban and academic settings, limited data exist on the feasibility and real-world outcomes of TMS implementation in rural healthcare settings. The purpose of this study is to highlight the feasibility …