Digital Commons Network^™

Elevated Plasma Cholesterol Improves Sepsis Outcome By Promoting Hepatic Metabolic Reprogramming, Qian Wang, Jianyao Xue, Ling Guo, Dan Hao, Misa Ito, Rianna Reese, Bin Huang, Congqing Wu, Xiang An Li

Markey Cancer Center Faculty Publications

Background – Sepsis is a life-threatening condition with high mortality and limited therapeutic options. This study investigated the association between plasma cholesterol levels and sepsis survival and explored the mechanisms by which elevated cholesterol confers protection. Methods – We analyzed 2, 787 sepsis patients from the MIMIC-IV database, comparing cholesterol levels between 28-day survivors and non-survivors and assessing mortality risk using multivariable Cox regression. To test causality, C57BL/6J mice were fed either a high-cholesterol diet (HCD) or a regular diet (RD) before cecal ligation and puncture (CLP). Results – Survivors had significantly higher cholesterol than non-survivors (median 135 vs. 126 …

Income As A Moderator Of Stress And Yoga Practice Among Black Women, Renee Jaxel

Walden Dissertations and Doctoral Studies

No abstract provided.

Developing An Effective Clinical Supervision Structure In An Outpatient Mental Health Group Practice, Kourtney Dockery

Walden Dissertations and Doctoral Studies

No abstract provided.

Trauma-Informed Intake Standardization Equitable Approach, Ketura James

Walden Dissertations and Doctoral Studies

No abstract provided.

Staff Education On Improving Primary Care Depression Screening With The Patient Health Questionnaire-9, Patience Amune

Walden Dissertations and Doctoral Studies

No abstract provided.

Parents Caring For Adult Children With Co-Occurring Disorders: A Phenomenological Study, Cynthia D. Williams

Journal of Social, Behavioral, and Health Sciences

The purpose of this study was to explore and understand the lived experiences of parents caring for an adult child, aged 18 to 30 years, with a co-occurring mental health and substance use diagnosis, with attention to how caregiving intersects with trauma, resilience, and systemic challenges. To guide this exploration, the Resilience Trauma Negotiation (RTN) framework was introduced to examine how exposure, appraisal, coping responses, and systemic context intersect to shape the complex realities of caregiving. Using Moustakas’s seven-step transcendental phenomenological approach, semi-directed interview questions were facilitated with 14 caregivers. Data were transcribed, coded, and analyzed to identify emerging themes …

Walking Easy, Grayson P. Isley

Bachelor of Architecture Theses - 5th Year

This thesis aims to aid in connecting an otherwise fragmented inaccessable area through safe and enjoyable spaces.

Ndls Communicator: Week Of 05.11.26, Notre Dame Law School

NDLS Communicator

The Latest News

• Class of 2026 Law School Commencement
• Notre Dame Exoneration Justice Clinic Client Iris Seabolt’s Murder Conviction Vacated, New Trial Ordered

Student News

• Dennis Wieboldt, 3L

Alumni News

• Paulita A. Pike, ’93 B.A., ’96 J.D.

Faculty Briefs

• Dean G. Marcus Cole and Paul Miller
• Paolo Carozza
• Carter Snead
• Lloyd Hitoshi Mayer
• Fr. John Paul Kimes
• Haley Proctor
• Rev. Patrick Reidy, C.S.C.
• A.J. Bellia
• Yan Yu

Events

COMMENCEMENT 2026

FRIDAY, MAY 15

• Law School Awards Ceremony 1:30 p.m., Dahnke Ballroom, Duncan Student Center
• Law School Reception and Champagne Toast with Dean Marcus Cole, graduates, families, faculty, and staff 5:30 …

Letter From The Editors, Larissa Oliveira Pires, Selcuk Dogan, Hui Jin, Joe Pellegrino

International Journal for the Scholarship of Teaching & Learning

This letter introduces the first issue in volume 20 of the International Journal of the Scholarship of Teaching and Learning (ijSoTL). This issue marks 20 years of sustained SoTL efforts at Georgia Southern. In those two decades the higher education landscape has changed significantly, bringing us to a time that is challenging and fraught with anxiety, but also full of promise and potential. The common threads that run through the articles in this issue, agency, engagement, and community, remind us that, although the means by which we achieve it are always shifting, our fundamental goal is to help …

Computational Study Of Household Plants As Immunomodulators On Human Metapneumovirus, Elda Zaelita Nurul Raizma, Devia Angelina Sopian, Handika Maulana Alifianto, Jasmine Rizkyta Yahya, Tanaya Aryo Jalu Bimantoro, Yuriza Eshananda

Chimica et Natura Acta

Human metapneumovirus (HMPV) is a causative agent of acute lower respiratory tract infections, especially in children. Until now, there are not many natural-based immunomodulatory therapies available. This study aims to explore the potential of household plants from the Syzygiumand zingiber Genus as immunomodulators against HMPV using computational studies. The target receptor used is RNA-dependent RNA polymerase (RdRp), a vital enzyme in HMPV genome replication. The methods used include molecular docking, validation of biological activity through Way2Drug and evaluation of pharmacokinetic feasibility using Lipinski’s Rule of Five. Based on the docking results, the compounds with the strongest binding affinity are myricetin …

How Well Are We Preparing U.S. Youth With Down Syndrome For Health Care Transition? A Mixed-Methods Study Assessing Provider Support And Exploring Caregiver Experiences, Suman Kanti Chowdhury

USF Tampa Graduate Theses and Dissertations

Background: Health care transition (HCT) preparation is a structured process that empowers youth to take ownership of their health care as they transition into adulthood. Youth with Down syndrome (DS), a common genetic disorder associated with a high burden of co-occurring conditions, require HCT preparation support at a higher rate than their typically developing peers. Although transition preparation has been examined across various chronic conditions, few studies have focused on youth with DS. Moreover, prior research was limited by methodological constraints, including the lack of a validated HCT index, a small sample size, outdated estimates, and a lack of a …

Effective Technological Integration Strategies For Improving Operational Efficiency And Competitive Advantage In Small Businesses, Tamara Wallace

Walden Dissertations and Doctoral Studies

No abstract provided.

Effects Of A Structured Fall Prevention Education Program On Staff Knowledge And Confidence, Gifty Danso

Walden Dissertations and Doctoral Studies

No abstract provided.

Effective Strategies Leaders Of Nonprofit Organizations Use To Engage Volunteers, Amy Kathleen Ramirez

Walden Dissertations and Doctoral Studies

No abstract provided.

Expatriate Employees’ Workplace Experiences With Cultural Intelligence, Leader-Member Exchange, And Retention Intent, Katherine Keene-Montgomery

Walden Dissertations and Doctoral Studies

No abstract provided.

Aligning Nutrition Screening Workflows To Improve Early Identification Of Pressure Injury Risk In Hospitalized Adults, Stephanie M. Vigil

Walden Dissertations and Doctoral Studies

No abstract provided.

Challenges In Fulfilling The Political Rights Of Indonesian Migrant Workers In Taiwan: A Case Study For The 2024 General Election, Ardli Johan Kusuma, Dini Putri Saraswati, Jati Satrio

Jurnal Wacana Politik

Political rights are part of human rights guaranteed by international law and the Indonesian constitution. However, Indonesian migrant workers (PMIs) in Taiwan face various challenges in exercising their right to vote in the 2024 elections. This research analyzes the obstacles faced by PMIs in Taiwan in the democratic process using politic of citizenship framework by Stokke. The research method used is a qualitative approach with semi-structured interviews with various relevant stakeholders. The results of this study show that the main obstacles to the implementation of elections for migrant workers in Taiwan are limited access to election information, differences in regulations …

Serving The Poor While Securing The Vote Islamic Parties And Welfare Program In Decentralized Indonesia, Luthfi Makhasin, Burhan Yahya, Indaru Setyo Nurprojo, Ahmad Rofik

Jurnal Wacana Politik

Indonesia is a Muslim-majority country with complex and diverse social and economic welfare problems. These welfare issues sometimes become sensitive electoral issues used to mobilize electoral support in elections. One of the welfare problems experienced by its citizens is the issue of inhospitable housing (Rumah Tidak Layak Huni / RTLH). This article seeks to explain how RTLH has become an electoral issue through the conceptual framework of political linkage. It begins with the question of how Islamic parties contribute to overseeing welfare programs in general and, more specifically, the handling of RTLH at the local level. In contrast to much …

Dynamic Trust Calibration, Bruno Miranda Henrique

Dartmouth College Ph.D Dissertations

Trust calibration between humans and Artificial Intelligence (AI) is crucial for optimal decision-making in collaborative settings. Excessive trust can lead users to accept AI-generated outputs without question, overlooking critical flaws, while insufficient trust may result in disregarding valuable insights from AI systems, hindering performance. Despite its importance, there is currently no definitive and objective method for measuring trust calibration between humans and AI. Current approaches lack standardization and consistent metrics that can be broadly applied across various contexts, and they don’t distinguish between the formation of opinions and subsequent human decisions. This thesis brings a novel and objective method for …

Disinformation, Polarisation And Digital Campaigns: A Comparative Study Of Political Communication In The Online Sphere, Agus Sugiharto, Wijayanto Wijayanto, Kushandajani Kushandajani, Nurul Hasfi

Jurnal Wacana Politik

Digital political campaigns have become a key phenomenon in contemporary politics. They significantly transform the patterns of communication between political parties, candidates, and voters. This study aims to analyze the development, dynamics, and implications of digital political campaigns on voter behavior as well as political communication strategies in the era of information technology. Using a qualitative approach through literature review of scholarly articles, the results show that digital political campaigns offer high efficiency in reaching a broad audience and enable the personalization of messages based on big data and predictive analytics. However, this practice also brings new challenges, such as …

Firm-Level Tournament Incentives And Social Decoupling: Evidence From The United States, Mohamed Khalifa, Ahmed Aboud, Soad Kh Ali

All Works

This study investigates whether tournament-based executive incentives exacerbate social decoupling. Using 4468 firm-year observations from S&P 500 firms between 2010 and 2022, we find that stronger tournament incentives are associated with higher levels of social decoupling. This association is stronger in firms without ESG-linked compensation, those facing higher product market competition, and those with greater board co-option. Additional analyses indicate that increased agency costs constitute an important channel. The analysis employs firm and year fixed-effects regressions and is supplemented by alternative decoupling measures, change-on-change analysis, instrumental variable estimation, and a Heckman two-stage model. This study advances the literature on executive …

From Sprawl To System: Reframing Suburban Thresholds For Density And Social Connectivity, Quincy A. Smith

Bachelor of Architecture Theses - 5th Year

Suburban form is a fragmented and low-density system of sprawling divisions which prevents social connection, carrying a particularly adverse effect for low-income families that cannot offset these attributes with economic bandages. My thesis asks how suburban elements can be implemented at the urban and architectural scale to create an accessible and connected system which results in both individual expression and communal opportunity. More specifically, this thesis aims to translate the thresholds of prototypical suburban typologies into a structural and circulatory framework.

Stan Allen’s field condition concept is explored for the urban level research methodology, introducing repetition and the grid to …

Interweaving Cairo's Urban Fabric: The Formal, The Informal And The Contemporary, Hagar Ahmed

Bachelor of Architecture Theses - 5th Year

Architecture is a negotiation between memory and change, preservation and erasure. In Cairo, a city layered with history, rapid development threatens historic areas and informal settlements (AlSayyad, 2011). While monumental heritage preservation is institutionalized, informal urban fabrics are often excluded from heritage discussions and planning. This research explores Mansheyet Nasser, or Garbage City, an informal settlement between Islamic Cairo and the Mokattam plateau. Over the past fifty years, Zabbaleen residents have built a communal waste collection and recycling system that processes up to 80% of materials, outperforming many regulated cities (Fahmi and Sutton, 2010; Didero, 2011). This infrastructure is both …

A Timely Warning: Clock Drawing Errors In Young Adults And The Long-Term Validity Of Cognitive Screens, Alastair Smith, Sarah Salo

School of Psychology

Objective: The clock drawing test (CDT) assesses multiple cognitive functions, including visuospatial construction and executive planning, and it is a core feature of many cognitive screens. Recent evidence indicates that young adults may experience difficulties producing an accurate response and we present a closer examination of generational differences in CDT performance in the context of the Montreal Cognitive Assessment (MoCA), where a notable failure rate was observed in our young adult respondents. Method: A total of 165 younger adults (18–35 years) and 53 healthy older adults (65–93 years) completed the MoCA as part of a larger study. CDT performance was …

Karstic Cavities Underground Investigation: Gpr And Geotechnical Data Correlation, Mehrez Jamei, Mabrouk Abdelkader, Anwar Ahmed, Yahya Alassaf

Journal of Sustainable Mining

This paper focuses on the methodology involving ground penetration radar (GPR) for detecting and localizing random cavities in underground limestone soil, in conjunction with geotechnical data. A GPR survey was conducted alongside field and laboratory geotechnical tests at a field where mining activities are now promoted (Saudi Arabia Northern Borders Province). The paper presents correlations between the instantaneous amplitude of the reflected electromagnetic (EM) waves and rock quantification distributed (RQD), recovery rock parameter (REC), and uniaxial compressive strength (UCS). The GPR investigation proved to be an efficient nondestructive geophysical method for determining: 1) the …

Pertanggungjawaban Hukum Pemerintah Terhadap Insiden Siber Kebocoran Data Pribadi, Shafira Meutia Syahrial, Edmon Makarim, Zahrashafa Putri Mahardika, Ayu Galuh Anggraini

Technology and Economics Law Journal

The United Nations declared the internet a global facility. Over the past decade, the urgency of efforts to protect the safety and security of cyberspace has increased exponentially with numerous malicious cyber incidents impacting infrastructure that provides services to the public. The internet is a communication channel related to the lives of many people, so all countries have a role to protect the internet. The preamble to the 1945 Constitution mandates the formation of a government to protect the Indonesian nation. The government is responsible for state administration based on Article 40 of the ITE Law, particularly in the case …

The Distributional Effects Of Feed-In-Tariff Policy For Renewable Energy In Japan, Kai Gee

CISLA Senior Integrative Projects

No abstract provided.

Mismatch Negativity (Mmn) And Neurodevelopmental Outcomes In Children Born Preterm, Aidee León Lúa

Theses - ALL

Premature birth is a leading factor contributing to neurodevelopmental disorders, including autism and cognitive disabilities. Early detection measures can help children access services earlier, even before behavioral traits manifest. Event-related potentials (ERPs), measured though electroencephalography (EEG), are objective and non-invasive methods to study brain activity in children born preterm. The mismatch negativity (MMN), measured by the difference in neural response to alternating frequent and rare stimuli, has been associated with cognitive abilities in preterm children, but its relation to autistic traits remains underexplored. The present study examined whether speech evoked MMN amplitude and latency in children born preterm between 5 …

Interdisciplinary Practices In The Band Room: Repertoire As A Tool To Enrich Student Learning, Ainsley L. Brouse

Theses - ALL

Interdisciplinary learning is an educational theory approach that emphasizes the importance of incorporating content from different subject areas into the teaching of one’s own topic of study. Research has presented that the use of interdisciplinary teaching practices can have several benefits on students' learning outcomes and overall academic success. Music has deep and rich historical roots that can provide students a more hands-on experience with the concepts and events they are learning in their history classes. The use of interdisciplinary practices through specific repertoire selections will not only provide students with a deeper, more meaningful experience with the music they …

Brief Candles: Memory, Degradation Of Time, Indices And Activation, Jared A. Dominique

Theses - ALL

This thesis explores the relationship between landscape, memory, and image-making through a multidisciplinary practice spanning photography, painting, and collage. Rooted in early experiences with skateboarding as a framework, the work adopts a subcultural way of seeing that reinterprets urban space as fluid, contingent, and open to reconfiguration. This perspective informs an ongoing investigation of post-industrial and altered environments as sites marked by both physical and historical violence. The project frames these landscapes as “spectral,” holding traces of human activity, memory, and absence. Alongside this external mapping, it examines an internal landscape shaped by visual memory, personal experience, and mediated imagery, …