Digital Commons Network^™

Phase Ii Trial Of Sodium Phenylbutyrate And Taurursodiol In Wolfram Syndrome, Fumihiko Urano, Bess A. Marshall, Stacy Hurst, Amy Robichaux-Viehoever, Saumel Ahmadi, Tamara Hershey, Gregory Van Stavern, Paulina Cruz Bravo, Jennifer Powers Carson, John Pesko, Kelly Fox, Nathalie Erpelding, Camille L Bedrosian

2020-Current year OA Pubs

PB&TURSO was associated with improved or stabilized pancreatic function, vision, and overall symptom burden in individuals with Wolfram syndrome, a rare and progressive degenerative disease.

Within Melbourne: Landscape, Labor, And Material Culture In A Derbyshire Parish, 1650-1750, Mia Powell

Senior Honors Papers / Undergraduate Theses

In May of 1695, a group of inhabitants walked the grounds of the English locality of Melbourne (Derbyshire) and collected demographic data from every household within the parish boundaries. From this perambulation came a uniquely detailed census-type listing. Combining that listing with other available sources, including probate records, criminal litigation, property disputes, financial papers, antiquarian accounts, maps, and enclosure agreements from across seven record offices, this project uncovers the complex social and economic developments experienced by those who lived in Melbourne from 1650 to 1750. To analyze this well-documented parish, this thesis utilizes various methodologies. Nominal record linkage connects Melbourne’s …

Longitudinal Changes In Cognition And Brain Imaging In Persons With Human Immunodeficiency Virus, James Kennedy, Sarah A Cooley, June Roman Fox, Kalen J Petersen, Elizabeth Westerhaus, Pat Reid, Linet Lopez, Beau M Ances

2020-Current year OA Pubs

BACKGROUND: As persons with human immunodeficiency virus (PWH) live longer, interactions between human immunodeficiency virus (HIV), aging, and structural brain integrity become increasingly vital for understanding cognitive disorders. This study analyzed the effects of aging, HIV serostatus, and viral load on cognition and brain volumes in a large cohort of persons without HIV (PWOH), PWH with undetectable virus (PWHU) (HIV RNA ≤50 copies/mL), and PWH with detectable virus (PHWD) (HIV RNA >50 copies/mL). Cross-sectional and longitudinal data were included.

METHODS: Cognitive composites (NPZ4) and brain volumes were obtained from 259 PWOH, 264 PWHU, and 84 PWHD with a total of …

Quantification Of Sarm1 Nadase Activity In Human Peripheral Blood Mononuclear Cells, Lila F Dabill, Ivana R Shen, Jennifer M Brazill, Alicia Neiner, Yo Sasaki, Erica L Scheller

2020-Current year OA Pubs

SARM1 (sterile α and TIR motif-containing protein-1) is an NADase enzyme that serves as the central executioner of Wallerian axon degeneration. Given this, SARM1 is of high interest as a candidate therapeutic target, and SARM1 inhibitors are currently in clinical trials for treatment of neurodegeneration. Beyond neuroscience, emerging studies reveal that SARM1 may also drive aspects of bone fragility, liver pathology, adipose expansion, and insulin resistance in metabolic disease. However, we lack methods to quantify SARM1 activation in humans to better define patients at high risk of SARM1-mediated tissue damage. Unlike neurons, peripheral blood mononuclear cells (PBMCs) represent an easily …

Short-Term Legume Cover Crops Following Maize Only Marginally Impact Winter Cereals Under Conservation Tillage Management, Arun D. Jani, John E. Erickson, Ramon G. Leon, C. Wesley Wood, Diane Rowland, Heather A. Enloe, Michael J. Mulvaney

Biology, Agriculture and Chemistry Faculty Publications and Presentations

Context: Warm-season legume cover crops in subtropical environments provide many agroecosystem services but have not been widely adopted because their use usually entails replacing cash crops. Planting short-term legume cover crops following maize (Zea mays L.) to replenish soil nitrogen (N) pools for cool-season cash crops, such as wheat (Triticum aestivum L.), is an innovative approach for integrating legumes into subtropical cereal cropping systems that has not been widely investigated.

Objectives: A maize – legume cover crop – wheat cropping sequence under conservation tillage management was investigated with the following objectives: 1. Evaluate the performance of short-term cowpea [Vigna unguiculata …

Level Of Comfort And Barriers To Pediatric Vaccination Among Pharmacy-Based Immunizers In California, Laressa Bethishou, Karl Hess, Richard Beuttler, Jeffery Goad

Pharmacy Faculty Articles and Research

Background

Pharmacists are increasingly recognized as accessible immunizers, yet pediatric vaccination rates in community pharmacies remain lower than those for adults, likely due to unique barriers. This study aimed to assess the comfort level of pharmacy-based immunizers in California with administering vaccines to pediatric patients and to identify barriers limiting their participation in pediatric immunization.

Methods

An IRB-approved, cross-sectional survey was distributed electronically to pharmacists, student pharmacists, and pharmacy technicians administering vaccines in California community pharmacies between November 2022 and February 2023. The survey measured comfort with vaccinating pediatric age groups, perceived barriers, and collected demographic data. Data analysis included …

Red, Blue, And Bordered: Factors Influencing Immigration Attitudes, Estefania Morales Vilchis

Political Science Student Papers and Posters

The paper will explore the various social and individual variables that will impact how people perceive immigration as either beneficial to society or a societal threat. Some of the primary variables that will be examined in detail are one’s political affiliation, age, and geographical location; this will address the profound "why" behind our current beliefs on newcomers. The study will particularly address the "Contact Hypothesis" versus "Group Threat Theory" through the lens of how one's personal experiences with immigrants, or lack of, will shape public opinion. The study will focus on the rising psychological issue of "demographic anxiety", specifically, fears …

A Comparative Performance Analysis Of Task Allocation Methods In Uav-Sdn Networks, Yasameen Ali Al Janabi, Ahmed Mhdi Al-Salih

Journal of Intelligent Informatics, Networking, and Cybersecurity

Task allocation is really important for how unmanned aerial vehicle-software-defined networking networks work and how much energy they use. This is especially true when the network is big or small and when things around it change. We looked at three ways to assign tasks: giving them out randomly giving them out in a manner that maintains load balance, and using something called ``particle swarm optimization'' We tried these methods in two situations: when the unmanned aerial vehicle-software-defined networking network is in open space and when it has to deal with obstacles. We used several unmanned aerial vehicles and tasks: 10 …

Miss Ogilvy Does Not Find Herself: The Repression Of Queer Expression Post World War I, Kennedie Krieger

2026 Symposium

World War l was a historical period of intense societal change, and although it brought upon a lot of devastation, there were also groups of people that experienced liberation because of the war. Radclyffe Hall’s short story “Miss Ogilvy Finds Herself” is an example of the ways in which the war offered relief for queer women who had previously been expected to exist within rigid gender roles. Through an uncommon perspective, readers are able to get a sense of the ways in which gendered societal expectations shifted during the war and the positive outcomes this brought about. Although these hopeful …

Gyntok: The Influence Of Social Media On The Gynecologic Health Of Adolescents And Young Adults, Katherine Lukas Md, Madeline Ross Md, Ms, Tazim Dowlut-Mcelroy, Lauren Roth Md, Patricia Huguelet Md, Shanna Combs Md, Ana Patricia Torga Md, Eugenie Lehembre-Shiah Md, Martha Perry Md, Swetha Naroji Md, Mba

Research Showcase

Background:

Social media plays a significant role in improving access to information regarding gynecological health. However, exposure to misinformation is prevalent, and studies have found that gynecological content on social media is often low quality and inaccurate. Despite the widespread use of social media among adolescents and young adults (AYA), the extent to which it influences their gynecological health remains unclear.

Objectives/Goal:

This study aims to characterize the influence of social media on gynecological health in AYAs, evaluate the impact of digital marketing, and identify strategies used to assess the credibility of online content.

Methods/Design:

This IRB-approved multi-site, cross-sectional survey …

The Making Of An Extremist: How Do We Become Someone Else’S Nightmare?, María Paula Morales

The Confluence

This article explores how ordinary people can be pulled into extremist movements and what psychological forces drive that process. It looks at three perspectives: social identity theory, which explains how group belonging shapes behavior, identity development, which shows how people searching for meaning may find it in extremist causes; and social neuroscience, which connects radicalization to brain activity linked to fear, loyalty, and moral judgement. Together, these approaches show that radicalization is not simply about ideology but about identity, emotion, and belonging. By understanding these dynamics, we can find better ways to prevent extremism and promote healthier, more inclusive communities.

The Purpose Of Life: An Analysis Of The Secret Life Of Walter Mitty As A Cinematic Guide To Eudaimonia, Eric W. Stroud

The Confluence

This paper examines the moral formation of the protagonist of the film The Secret Life of Walter Mitty (2013) through the framework of Aristotelian virtue ethics. Though extensive research has been conducted on the use of film as a vehicle for moral education and a tool for ethics pedagogy, there exists a demonstrable gap in research which applies the principles of virtue ethics to character analysis in film. This paper presents a scene-based, qualitative analysis comparing the actions of the main character to the model of habituation of virtue as presented in The Nicomachean Ethics by Aristotle. In observing the …

Hammurabi’S Laws: Ancient Traditions Of Violence, Aaron Secrist

The Confluence

The tradition of enforcing private property through violence is truly ancient, and goes back thousands of years to the first civilizations. There exists a prevailing attitude that contemporary culture is more “civilized” than the first organized societies – and while it’s true in some ways, our laws are still remarkably similar to those practiced in antiquity. In the following essay, I analyze the Law Code of Hammurabi and examine its parallels to the way laws function today. First, I will provide context for the technological advances that made the first city-states possible, then give a cultural and economic overview of …

From Your Pov: Using Narrative-Focused Methodology To Study Psychological Correlates Of Sexual Health Behaviors, Zoë E. Sweaney, Stephanie Afful

The Confluence

How far would you go (or not go) to protect yourself from risky sexual behaviors? Additionally, what influence does our gender identity and socialization have on these decisions? In the current series of studies, a story-driven safe-sex behavioral assessment was developed and administered to participants to assess the relationships amongst psychological indices, personal values, and sexual health. This research confirms the validity of an instrument that queries sensitive data while controlling for social desirability concerns. The applications of this research are especially pertinent to improving upon interpersonal communication, sexual health education, and women’s sexual health advocacy.

Modeling Psychological And Demographic Predictors Of Analog Astronaut Mission Participation, Christian Yeara Herrero, Frányerson R. López Ochoa, Mackenzie Thomas, Phoebe Fleshman

Student Research Symposium (SRS)

As plans accelerate to send humans into orbit and to other celestial bodies, whether to lunar outposts, Mars bases, or commercial space stations, it becomes increasingly important to understand how to maintain healthy, cohesive, and productive crews in confined, isolated environments. A practical way to study human adaptation to these conditions is through analog astronaut missions on Earth. Although imperfect, these facilities provide the closest Earth-based simulation of space mission conditions. Currently, over ten analog research centers are operating worldwide, including NASA’s Human Exploration Research Analog (HERA) and the Crew Health and Performance Exploration Analog (CHAPEA) habitats. Selecting and recruiting …

Dynamic Homeostasis In Relaxation And Bursting Oscillations, Christopher J. Ryzowicz

Biology and Medicine Through Mathematics Conference

No abstract provided.

On Knowledge As An Act, Zakaria Al Shmaly

Emancipations: A Journal of Critical Social Analysis

No abstract provided.

Experience As A Site Of Knowing, Daphne Nicolaidis Saunders

Emancipations: A Journal of Critical Social Analysis

No abstract provided.

The Politics Of Literature In Dider Eribon’S Returning To Reims: An Emancipatory Review, Noa De Kievit

Emancipations: A Journal of Critical Social Analysis

This paper examines Didier Eribon’s Returning to Reims (2009) as a model for understanding how literary and autobiographical writing can enact ''the politics of literature.'' While Eribon is widely recognized as a sociologist, his “autosociobiography”—tracing his trajectory from a working-class upbringing to an academic career alongside his coming out—blends personal narrative and sociological insight to illuminate structural inequalities and social marginalization. Reading the text through Jacques Rancière’s concept of the politics of literature, I argue that Eribon simultaneously expands the scope of what is visible, sayable, and thinkable, while reflecting critically on the interpretive authority he exercises. Building on Caroline …

Resilience Otherwise: Ambivalence, Care, And The Cultural Politics Of Endurance Under Neoliberal Capitalism, Vered Ben David

Emancipations: A Journal of Critical Social Analysis

Over the past two decades, resilience has emerged as a central cultural keyword circulating across psychology, public policy, education, labor, and popular culture. Frequently celebrated as a marker of strength and adaptability, resilience has also become entangled with neoliberal forms of governance that relocate responsibility for managing insecurity onto individuals and communities. This analysis offers a critical cultural account of resilience as an ambivalent formation that operates simultaneously as a lived capacity for adaptation and as a normative demand that responsibilizes subjects under conditions of structural precarity. Drawing on scholarship in developmental psychology, political economy, and critical cultural theory, the …

Thinking Life: The Question Of Reproduction In Marx. Translated By James Chamberlain, Isabelle Garo

Emancipations: A Journal of Critical Social Analysis

No abstract provided.

Member Awards And Recognition

Virginia Dental Journal

No abstract provided.

How Do You Eat An Elephant?, James Schroeder

Virginia Dental Journal

No abstract provided.

How To Respond To A Negative Review, Lance Mccollough

Virginia Dental Journal

No abstract provided.

Dr. Thomas Upshur Turns 100, Stephanie N. Vlahos Dds

Virginia Dental Journal

No abstract provided.

Silver Diamine Fluoride- A New Weapon For Caries Arrest Is Now Fda Approved In Us, Harmeet Kaur Chiang Dds

Virginia Dental Journal

No abstract provided.

Letter To The Editor - Medicaid Extractions, Mark Turner Dds

Virginia Dental Journal

No abstract provided.

Letter To The Editor - Coincidence Or Reality?, Marvin E. Pizer Dds, Ms, Ma, Ficd

Virginia Dental Journal

No abstract provided.

President’S Message, Michael J. Link Dds

Virginia Dental Journal

No abstract provided.

Va Dent J July, August And September 2015

Virginia Dental Journal

No abstract provided.