Digital Commons Network^™

Migration And Resource Misallocation In China, Xiaolu Li, Lin Ma, Yang Tang

Research Collection School Of Economics

We structurally estimate the firm-level frictions across prefectures in China and quantify their aggregate and distributional implications. Based on a general equilibrium model with input and output distortions and migration, we show that the firm-level frictions are less dispersed and less correlated with firm productivity in richer prefectures. Counterfactual exercises show that reducing the within-prefecture misallocation increases aggregate welfare, discourages migration toward large prefectures, and reduces spatial inequality. Moreover, internal migration alleviates micro-frictions’ impacts on aggregate welfare and worsens their effects on spatial inequality.

The Distributional Impacts Of Transportation Networks In China, Lin Ma, Yang Tang

Research Collection School Of Economics

We document that the quality of roads and railroads vary substantially over time and space in China, and neglecting these variations biases the distributional impacts of transportation networks. To account for quality differences, we construct a new panel dataset and approximate quality using the design speed of roads and railroads that varies by vintage, class, and terrain at the pixel level. We then build a dynamic spatial general equilibrium model for multiple modes, transportation routes, and forward-looking migration decisions. Our findings demonstrate that disregarding quality differences leads to a median bias of approximately 31% in estimating real wage growth rates …

Panel Data Models With Time-Varying Latent Group Structures, Yiren Wang, Peter C. B. Phillips, Liangjun Su

Research Collection School Of Economics

This paper considers a linear panel model with interactive fixed effects and unobserved individual and time heterogeneities that are captured by some latent group structures and an unknown structural break, respectively. To enhance realism, the model may have different numbers of groups and/or different group memberships before and after the break. With preliminary nuclear norm regularized estimation followed by row- and column-wise linear regressions, we estimate the break point based on the idea of binary segmentation and the latent group structures together with the number of groups before and after the break by sequential testing K-means algorithm simultaneously. It is …

Who Watched Pre/Post-Lecture Tutorial Videos? Does Flipped Learning Help Beginners In Economics?, Bei Hong

Research Collection School Of Economics

The modern-day classroom is characterized by academic diversity, with students from varied backgrounds and with different levels of prior knowledge. To cater to the diverse abilities of students, this paper explored the use of flipped learning as a teaching approach in an introductory economics course. We investigated the effectiveness of 40 pre-lecture videos covering basic concepts and 27 post-lecture tutorial videos focusing on practice in improving students' exam outcomes, especially for beginners in economics who may require more support from instructors than other students. We collected data about video engagement and students' grades in progress assessments. Surveys were conducted to …

High Frequency Principal Component Analysis Based On Correlation Matrix That Is Robust To Jumps, Microstructure Noise And Asynchronous Observation Times, Dachuan Chen

Research Collection School Of Economics

This paper developed the high frequency estimation for the principal component analysis (PCA) based on correlation matrix. This estimation methodology is robust to jumps, microstructure noise and asynchronous observation times simultaneously, which is enabled by the newly proposed Truncated and Smoothed Two-Scales Realized Volatility (Truncated S-TSRV) estimator. The general framework of our methodology is constructed based on the estimation of realized spectral functions with respect to the spot correlation matrix. A new asymptotic representation for the element-wise estimation error of the spot correlation matrix estimate has been derived, resulting in a new bias correction term which is much more complex …

Designing An Optical Router Based On A Multimode-Interference Silicon-On-Insulator Coupler With Tunable Power Transmittance, Dana S. Akil, Muhammad A. Othman, Sherif M. Sherif, Mohamed A. Swillam

Faculty Journal Articles

The demand on fast and high-bandwidth data transmission is in continuous increase. These demands are highly dependent on optical signal manipulation, including switching, modulation, and routing. We demonstrate a two-port silicon optical router based on the multimode interferometer (MMI) configuration. The same MMI structure was used for both inward and backward waveguiding to reduce the total length of the device. A phase shifter consisting of two ring-like waveguides made of silicon p-n junctions was used to introduce the phase shift needed for optical routing upon voltage application. Two designs for the MMI optical router were studied: Firstly, a conventional MMI …

Highly Sensitive On-Chip Grating-Based Optical Sensor On Glass Substrate: Cost-Effective Design, Hesham A. Attia, Mulan E. Ahmed, Adel Shaaban Awad Elsharkawi, Mohamed A. Swillam

Faculty Journal Articles

This paper presents a novel on-chip optical sensing system using ion exchange technology and phase-shifted Bragg grating design. The sensor geometry has been optimized using a finite difference time domain (FDTD) solver to achieve maximum sensitivity and figure of merit (FOM). The proposed design offers high sensitivity to changes in refractive index and low fabrication costs. The ion exchange process used to create the sensor allows for precise refractive index control, optimizing the sensor’s sensitivity and FOM. A graded-index waveguide and a phase-shifted Bragg grating structure also contribute to the sensor’s high sensitivity. The proposed sensor design was tested for …

The Use Of Economic Indicators As Early Signals Of Stock Market Progress: Perspectives From Market Potential Index, Tarek Eldomiaty, Islam Azzam, Mostafa Fouad, Yasmeen Said

Faculty Journal Articles

The progress of financial markets depends on the way world investors foresee the market potential of the country of choice. Countries that are associated with favorable economic incentives are able to motivate investments in their respective stock markets. The objective of this paper is to examine the role of the many economic components which constitute the Market Potential Index in enhancing stock market progress. The methodology goes through testing and estimation. The tests include linearity versus nonlinearity (RESET), normality, and cointegration. The estimation includes cointegration regression and discriminant analysis to distinguish between high and low stock market progress. This study …

Regulating Business And Human Rights Through Soft And Hard Law: Lessons From International Nuclear Law, Christiane Ahlborn

Vanderbilt Journal of Transnational Law

No abstract provided.

Is Blood Thicker Than Water? Europe Must Work Together To Solve Its Impending Water Crisis, Vann Buchanan

Vanderbilt Journal of Transnational Law

No abstract provided.

Toward A South African Fair Use Standard, Taysir Awad

Vanderbilt Journal of Transnational Law

No abstract provided.

Advocating For Adoptions In Al Hol: How Intercountry Adoptions Could Ensure The Safety Of A Generation Of Lost Children, Jill Boggs

Vanderbilt Journal of Transnational Law

No abstract provided.

Migraines, Vasomotor Symptoms, And Cardiovascular Disease In The Coronary Artery Risk Development In Young Adults Study, Catherine Kim, Pamela J Schreiner, Zhe Yin, Rachael Whitney, Stephen Sidney, Imo Ebong, Deborah A Levine

Faculty, Staff and Student Publications

Objective: To examine whether vasomotor symptoms (VMS) and migraine headaches, hypothesized to be vasoactive conditions, are associated with greater risk for cardiovascular disease (CVD) events including strokes.

Methods: We performed a secondary data analysis of a subset of women (n = 1,954) in the Coronary Artery Risk Development in Young Adults (CARDIA) study, a population-based cohort, which began data collection at 18 to 30 y of age. We examined whether migraine headaches and VMS trajectories (characterized as minimal, increasing, and persistent) at CARDIA year 15 examination were associated with higher risk of CVD events and stroke (both ischemic and hemorrhagic) …

Comprehensive Analysis Identifies Variability In Pi3k Pathway Alterations In Triple-Negative Breast Cancer Subtypes, Reva K Basho, Li Zhao, Jason B White, Lei Huo, Roland L Bassett, Elizabeth A Mittendorf, Alastair Thompson, Jennifer K Litton, Naoto Ueno, Banu Arun, Bora Lim, Vicente Valero, Debu Tripathy, Jianhua Zhang, Beatriz E Adrada, Lumarie Santiago, Elizabeth Ravenberg, Sahil Seth, Clinton Yam, Stacy L Moulder, Senthil Damodaran

Faculty, Staff and Student Publications

Purpose: The PI3K pathway is frequently altered in triple-negative breast cancer (TNBC). Limited cell line and human data suggest that TNBC tumors characterized as mesenchymal (M) and luminal androgen receptor (LAR) subtypes have increased incidence of alterations in the PI3K pathway. The impact of PI3K pathway alterations across TNBC subtypes is poorly understood.

Methods: Pretreatment tumor was evaluated from operable TNBC patients enrolled on a clinical trial of neoadjuvant therapy (NAT; A Robust TNBC Evaluation fraMework to Improve Survival [ClinicalTrials.gov identifier: NCT02276443]). Tumors were characterized into seven TNBC subtypes per Pietenpol criteria (basal-like 1, basal-like 2, immunomodulatory, M, mesenchymal …

Patients With Advanced Cancer And Their Spouses Parenting Minor Children: The Role Of The Relationship Context In Parenting Concerns, Kathrin Milbury, Sujin Ann-Yi, Morgan Jones, Yisheng Li, Meagan Whisenant, Sania Yousuf, Victoria Necroto, Mariana Chavez Mac Gregor, Eduardo Bruera

Faculty, Staff and Student Publications

Objective: Patients with advanced cancer who parent minor children report parenting concerns and increased psychological distress. This cross-sectional study seeks to understand parenting-related issues in patients and spousal caregivers from a relationship perspective.

Methods: Patients with a metastatic solid malignancy and their spouses independently completed cross-sectional assessments of psychological distress (Hospital Anxiety and Depression Scale), parenting concerns (Parenting Concern Questionnaire) and efficacy (Cancer-Related Parenting Self-Efficacy Scale), and relationship measures (DAS-7, Couples' Illness Communication Scale, and Family Relationship Index).

Results: Of the 51 patients (57% female, 49% NHW, mean age 42 years) and spouses (43% female, 43% NHW, mean age of …

Correcting Ct Misregistration In Data-Driven Gated (Ddg) Pet With Pet Self-Gating And Deformable Image Registration, Peng Sun, M Allan Thomas, Dershan Luo, Tinsu Pan

Faculty, Staff and Student Publications

Background: Misregistration between CT and PET data can result in mis-localization and inaccurate quantification of functional uptake in whole body PET/CT imaging. This problem is exacerbated when an abnormal inspiration occurs during the free-breathing helical CT (FB CT) used for attenuation correction of PET data. In data-driven gated (DDG) PET, the data selected for reconstruction is typically derived from the end-expiration (EE) phase of the breathing cycle, making this potential issue worse.

Purpose: The objective of this study is to develop a deformable image registration (DIR)-based respiratory motion model to improve the registration and quantification between misregistered FB CT and …

The Status And Challenges For Prostate Stereotactic Body Radiation Therapy Treatments In United States Proton Therapy Centers: An Nrg Oncology Practice Survey, Jiajian Shen, Paige A Taylor, Carlos E Vargas, Minglei Kang, Jatinder Saini, Jun Zhou, Peilong Wang, Wei Liu, Charles B Simone, Ying Xiao, Liyong Lin

Faculty, Staff and Student Publications

Purpose: To report the current practice pattern of the proton stereotactic body radiation therapy (SBRT) for prostate treatments.

Materials and methods: A survey was designed to inquire about the practice of proton SBRT treatment for prostate cancer. The survey was distributed to all 30 proton therapy centers in the United States that participate in the National Clinical Trial Network in February, 2023. The survey focused on usage, patient selection criteria, prescriptions, target contours, dose constraints, treatment plan optimization and evaluation methods, patient-specific QA, and image-guided radiation therapy (IGRT) methods.

Results: We received responses from 25 centers (83% participation). Only 8 …

A Phase 1 Trial Of 8-Chloro-Adenosine In Relapsed/Refractory Acute Myeloid Leukemia: An Evaluation Of Safety And Pharmacokinetics, Vinod Pullarkat, Lisa S Chen, Joycelynne Palmer, Jianying Zhang, Timothy W Synold, Ralf Buettner, Le Xuan Truong Nguyen, Guido Marcucci, Ni-Chun Tsai, Yan Wang, James O'Hearn, Varsha Gandhi, Steven T Rosen

Faculty, Staff and Student Publications

Background: This study evaluated the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of 8-chloro-adenosine (8-Cl-Ado) in patients with relapsed/refractory acute myeloid leukemia (AML).

Methods: 8-Cl-Ado was administered daily for 5 days; the starting dose was 100 mg/m2 , the highest dose tested was 800 mg/m2 . The end points were toxicity, disease response, and PK/PD measurements.

Results: The predominant nonhematologic toxicity was cardiac with grade ≥3 toxicity. Plasma PK in all patients suggested heterogeneity among patients, yet, some dose-dependency for the accumulation of 8-Cl-Ado. Two 8-Cl-Ado metabolites accumulated at similar levels to 8-Cl-Ado. Cellular PK in eight patients indicated accumulation of …

Empirically Derived Principles For Research Funding Success: A Primer For Early Career Academic Investigators, Kareem A Wahid, Michael K Rooney, Jillian R Gunther, Amy C Moreno, Chelsea C Pinnix, Charles R Thomas, Clifton D Fuller

Faculty, Staff and Student Publications

No abstract provided.

Clinical And Dosimetric Results Of Proton Or Photon Radiation Therapy For Large (>5 Cm) Hepatocellular Carcinoma: A Retrospective Analysis, Rodney Cheng-En Hsieh, Ching-Hsin Lee, Hsiao-Chieh Huang, Shu-Wei Wu, Chen-Yu Chou, Sheng-Ping Hung, Chao-Wei Lee, Sunil Krishnan, Bhanu Prasad Venkatesulu, Jin-Chiao Lee, Yung-Chih Chou, Kun-Ming Chan, Po-Ting Lin, Wei-Chen Lee, Chen-Chun Lin, Shen-Yen Lin, Ji-Hong Hong

Faculty, Staff and Student Publications

Purpose: Our purpose was to report the clinical and dosimetric attributes of patients with large unresectable hepatocellular carcinoma (HCC) undergoing proton or photon radiation therapy.

Methods and materials: We retrospectively analyzed the outcomes and dosimetric indices of 159 patients with >5 cm nonmetastatic HCC who underwent definitive radiation therapy using either protons (N = 105) or photons (N = 54) between 2014 and 2018. Additional photon plans were performed in the 105 proton-treated patients using the same dose prescription criteria for intragroup dosimetric comparison.

Results: After a median follow-up of 47 months, patients with biologically effective dose (BED10) ≥ 75 …

Esophageal Cancer Outcomes After Definitive Chemotherapy With Intensity Modulated Proton Therapy, Chike O Abana, Pim J Damen, Peter S Van Rossum, Pablo Lopez Bravo, Xiong Wei, Julianne M Pollard-Larkin, Paige L Nitsch, Mariela Blum Murphy, Wayne L Hofstetter, Zhongxing Liao, Steven H Lin

Faculty, Staff and Student Publications

PURPOSE: The effectiveness of intensity-modulated proton therapy (IMPT) for esophageal cancer treated with definitive concurrent chemoradiation therapy remains inadequately explored. We investigated long-term outcomes and toxicity experienced by patients who received IMPT as part of definitive esophageal cancer treatment.

PATIENTS AND METHODS: We retrospectively identified and analyzed 34 patients with locally advanced esophageal cancer who received IMPT with concurrent chemotherapy as a definitive treatment regimen at The University of Texas MD Anderson Cancer Center from 2011 to 2021. The median IMPT dose was 50.4 GyRBE in 28 fractions; concurrent chemotherapy consisted of fluorouracil and/or taxane and/or platinum. Survival outcomes were …

Spectrophotometric Analysis Of Purple Urine Secondary To Methylene Blue And Hydroxocobalamin Co-Administration, Jeremy Hardin, Henrik Galust, Richard Franklin Clark, Binh Ly, Raymond Theodore Suhandynata

Faculty, Staff and Student Publications

BACKGROUND: The development of purple urine after methylene blue (methylthioninium chloride) and hydroxocobalamin co-administration is a rare clinical entity that has not been fully elucidated. A 47-year-old male presented to the emergency department with hypotension, cyanosis, and depressed mental status. The patient was noted to have profound peripheral and central cyanosis, as well as chocolate-colored arterial blood. He was treated with both methylene blue and hydroxocobalamin and developed purple urine for approximately 1 week.

METHODS: Color chromatography was performed by placing the patient's urine directly onto absorbent filter paper. Urine spectrophotometry was performed utilizing the NanoDrop One/One C UV-Vis Spectrophotometer. …

Cancer Patients With Clonal Hematopoiesis Die From Primary Malignancy Or Comorbidities Despite Higher Rates Of Transformation To Myeloid Neoplasms, Kelly S Chien, Faustine Ong, Kunhwa Kim, Ziyi Li, Rashmi Kanagal-Shamanna, Courtney D Dinardo, Koichi Takahashi, Guillermo Montalban-Bravo, Danielle Hammond, Koji Sasaki, Sherry A Pierce, Hagop M Kantarjian, Guillermo Garcia-Manero

Faculty, Staff and Student Publications

BACKGROUND: The occurrence of somatic mutations in patients with no evidence of hematological disorders is called clonal hematopoiesis (CH). CH, whose subtypes include CH of indeterminate potential and clonal cytopenia of undetermined significance, has been associated with both hematologic cancers and systemic comorbidities. However, CH's effect on patients, especially those with concomitant malignancies, is not fully understood.

METHODS: We performed a retrospective evaluation of all patients with CH at a tertiary cancer center. Patient characteristics, mutational data, and outcomes were collected and analyzed.

RESULTS: Of 78 individuals included, 59 (76%) had a history of cancer and 60 (77%) had moderate …

Study Of The Relationship Among Economic Variables In Cattle Production In A Region Of Peru, Based On Plithogenic Statistics, Ketty Marilú Moscoso-Paucarchuco, Michael Raiser Vásquez-Ramírez, Humberto Rafael Yupanqui-Villanueva, Wilfredo Fernando Yupanqui-Villanueva, Omar Arturo Vivanco-Nuñez, Manuel Michael Beraún-Espíritu, Rafael Jesús Fernández-Jaime, Edgar Gutiérrez-Gómez

Neutrosophic Sets and Systems

This paper is an in-depth study that starts from a preliminary one, where we surveyed 141 ranchers from the town of Coto-Coto in Peru to obtain as much information as possible about the relationship between two economic variables, Activity Cost and Financial Management. Furthermore, we study the correlation of the first one of them with three other economic vari ables. To do this, we process the survey data using logical operators with the support of the plithogenic statistics theory. These results given in the form of plithogenic values are logically aggregated and were converted to crisp values and studied through …

Applications Of Sets And Functions By Using An Open Sets In Fuzzy Neutrosophic Topological Spaces, Basker P, Broumi Said, Vennila J

Neutrosophic Sets and Systems

The definitions provided by the authors of the current study are offered together with a discussion of the recent advances that they have contributed. We begin with an introduction to ���� Fr#bϱN , which includes the concepts of closed and open sets. We explore characteristics in ����-βd#bϱN and ����-℮bϱN (ϱN), and provide an idea of obtained results by adding the notion of FNbϱN OS and analyzing a few of their properties in ��������. We've researched the contrasts between the derived, exterior, and frontier notions that are provided. We also looked at the ideas of 〈��bϱN〉��-functions and Γ��-segregated functions and examined …

Measurement Of The Effectiveness Of An Educational Program Inspired By Indigenous Knowledge For Forest Management, Applied To Forest Engineering Students At The National University Of Central Peru, Using The Neutrosophic 2-Tuple Linguistic Method, Melina Lisbet, Rubén Gelacio Caballero Salas, Milciades Aníbal Baltazar Ruiz, Carlos Eduardo Caballero Salas, Guillermo Ayllon Pinchi, Rolando Carlos Canteño Gavino, Keneth Reategui Del Aguila, Wilmer Ortega Chávez

Neutrosophic Sets and Systems

The “guide to Asháninka knowledge for forest management” is a document prepared by aca demics and scientists from the National University of Central Peru (NUCP) in the Faculty of Forestry Engineering, which includes the knowledge of this indigenous people about forest nature. Despite being ancestral knowledge, we believe that it can serve as a complement to the scientific study of the subject since it is based on knowledge accumulated over centuries of experience. The main purpose of this article is to determine the influence of the “Ashaninka knowledge guide for forest management” on the learning level of NUCP Forest Engineering …

A Photographic Exploration Of Wigi (Currently Called Humboldt Bay), Aldaron Laird

Trade & Scholarly Monographs

For decades, Aldaron has walked the shores of the bay, climbed its nearby sand dunes, and kayaked its entire periphery, taking over 25,000 photos that reveal the beauty of Wigi as it might appear in some magical, glimmering dream. From those thousands of photos, Aldaron selected 119 for this book. For each photo he kept, he discarded 209 others, which means that of those 25,000 images, he used less than one percent. We might think that taking all those photos required a tremendous amount of work, but it soon becomes clear that Aldaron did not work on this book, he …

Insecticide Contamination In Organic Agriculture: Evidence From A Long-Term Farming Systems Comparisons Trial, Ivonne Kampermann, David Bautze, Millicent Mapili, Martha Musyoka, Edward Karanja, Komi K.M. Fiaboe, Janet Irungu, Noah Adamtey

All Peer-Reviewed Publications

Synthetic pesticides applied in conventional agriculture to control pests tend to compromise ecosystem services, and their residues may contaminate organic agriculture. To understand the significance of this contamination, also in small-scale farming systems in sub-Saharan Africa, quantitative data is required. Therefore, we compared synthetic insecticide and botanical/biopesticide residues in conventional and organic agricultural production systems after nine years of continuous cultivation of a maize-based crop rotation system at two sites in Kenya. Our results show high detectable concentrations of synthetic insecticide residues (imidacloprid, acetamiprid, chlorpyrifos, and chlorantraniliprole) in conventional plant produce and soil. Furthermore, the organophosphate chlorpyrifos was detected at …

Masthead

UC Law Journal

No abstract provided.

Calculating The Harms Of Political Use Of Popular Music, Jake Linford, Aaron Perzanowski

UC Law Journal

When Donald Trump descended the escalator of Trump Tower to announce his 2016 presidential bid, Neil Young’s “Rockin’ in the Free World” blared from the loudspeakers. Almost immediately, Young’s management made clear that the campaign’s use of the song was unauthorized. Neil Young was not alone. Trump drew similar objections from dozens of artists during his first two presidential bids. But as a matter of copyright law, it is unclear whether artists can prevent their songs from being played at campaign rallies. Putting the intricacies of copyright licensing aside, what motivates artists to object to the use of their songs …