Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 167731 - 167760 of 1738424

Full-Text Articles in Entire DC Network

Addressing Food Insecurity Among College Students, Serena Plares May 2024

Addressing Food Insecurity Among College Students, Serena Plares

Capstone Projects and Master's Theses

In this capstone project, the focal topic was food insecurity and food assistance with the target population being college students attending California State University Monterey Bay. This demographic includes a diverse group of young adults from various socioeconomic backgrounds and cultures. Food insecurity is rampant across our country, county, and college campuses. It impacts families and individuals of all backgrounds and there is a need for knowledge pertaining to this topic and affordable, nutritious food access and resources. One in three children and one in four adults are affected by food scarcity in Monterey County and thirty-four percent of county …


Food For Thought: Addressing Food Insecurity In Public Schools For Optimal Student Success, Emma Stillwagon May 2024

Food For Thought: Addressing Food Insecurity In Public Schools For Optimal Student Success, Emma Stillwagon

Capstone Projects and Master's Theses

The focus issue addressed in this Capstone Project is the presence of food insecurity throughout a county on the coast of California and what can be done to improve it. This issue is important because of the negative impact that food insecurity has on students' health, development, and academics. An evidence-based argument is offered that public education has a responsibility to address food insecurity through its institutions as a means of supporting students' academic and developmental success. The stakeholder perspectives chosen were of 1 individual working as a Community Partnership Coordinator for a local food aid organization, one individual who …


Imposter Syndrome: Navigating As A First-Generation College Student, Jessica Hamm May 2024

Imposter Syndrome: Navigating As A First-Generation College Student, Jessica Hamm

Capstone Projects and Master's Theses

The focal topic of this capstone project is navigating imposter syndrome among first-generation college students. Imposter syndrome is an internal experience in which you believe you are less capable than others judge you to be. It is a mental state in which you doubt your own talents/abilities. In a community jeopardized by an influx of what is called imposter syndrome, there exist students who are high achieving yet fail to recognize their success as being earned or deserved. Imposter syndrome describes an individual who is high achieving yet fails to recognize their success as being earned, but instead attributes it …


The Vital Role Of School Bus Drivers In Supporting Students With Special Needs, Georgina Solano Zepeda May 2024

The Vital Role Of School Bus Drivers In Supporting Students With Special Needs, Georgina Solano Zepeda

Capstone Projects and Master's Theses

This capstone project addressed the challenges faced by new and experienced bilingual school bus drivers who transport special education students. According to the California Department of Education, transportation must be provided at no cost to those special education students ages 3-21 who are eligible as part of related services. The training for school bus drivers typically covers safe driving, vehicle operation, and basic student management. However, they often receive minimal or no specialized training to work with students with special needs. California had an estimated 38,000 school bus drivers in 2020, making it one of the states with the highest …


Mental Health Awareness In Adolescents And The Impact Of Social Media, Vanessa Clark May 2024

Mental Health Awareness In Adolescents And The Impact Of Social Media, Vanessa Clark

Capstone Projects and Master's Theses

This capstone project focuses on informing parents of the effects of social media on adolescents’ mental health. Adolescents are frequent users of social media as they are more likely to explore online content and be unaware of the potential dangers that can pose a threat to their mental health (Rapee et al. 2019). Due to social media being difficult to monitor at all times, along with advances in technology through school curriculums, we want to acknowledge its presence and usage. Social media allows the opportunity to connect with others digitally but there needs to be awareness of the potentially harmful …


Helping Preschool Students Understand Emotions, Kenia Escobar May 2024

Helping Preschool Students Understand Emotions, Kenia Escobar

Capstone Projects and Master's Theses

The focal topic of my capstone project is preschool-aged children’s social-emotional development. Young children are in the time they learn from experiences. New studies show that adults benefit from social-emotional learning (SEL) when it is implemented during early childhood (Newman & Moroney, 2019). The need for service provides preschool children with tools to help them feel a sense of belonging, express their feelings, and establish relationships. I have developed a series of activities and lessons to help preschoolers learn more about feelings and relationships. First, emotional self-awareness will be covered because when preschoolers become aware of their emotions, their leadership, …


Increasing Sportsmanship In Middle Childhood Sports, Treya Soriano May 2024

Increasing Sportsmanship In Middle Childhood Sports, Treya Soriano

Capstone Projects and Master's Theses

This capstone project focuses on children’s development of sportsmanship. Sportsmanship is the act of having a good attitude and playing fair. Good sportsmanship can be practiced by players, coaches, and spectators. The problem with sportsmanship in childhood sports is that there is a noticeable lack of sportsmanlike behaviors while participating in athletic competitions. This can include physical education class, a sports team, or just playing tag at recess. An estimation of 57.6% of youth in the United States participate in at least one sport (Bolter et al., 2018) and while they may not stick with it as they grow older, …


Increasing Social-Emotional Development In Early Childhood, Brianna Navarro May 2024

Increasing Social-Emotional Development In Early Childhood, Brianna Navarro

Capstone Projects and Master's Theses

This capstone project focuses on increasing social-emotional development of 5- to 7-year-old children. Social-emotional learning (SEL) is a methodology that helps students of all ages better comprehend their emotions, feel emotions to the fullest extent, and demonstrate empathy for others. These learned behaviors are then used to help students make positive, responsible decisions, create frameworks to achieve their goals and build positive relationships with others. Researchers indicate that social-emotional learning promotes scholastic achievement, well-being, and positive life outcomes and can be a powerful tool for prevention and resilience when embedded with intentionality in curriculum, instruction, and school climate (Durlak et …


The Need For Mental Health Resources In Migrant Farm Working Families, Juliana Cecilia Garcia May 2024

The Need For Mental Health Resources In Migrant Farm Working Families, Juliana Cecilia Garcia

Capstone Projects and Master's Theses

The focus of my capstone project is on providing mental health resources for migrant workers and their families. Language barriers and cultural differences are a big obstacle for these parents. Because of this, it is hard for parents to seek help. Language barriers can make communicating one’s struggles with healthcare providers difficult. These topics can be difficult for anyone to put into words, but it’s especially challenging for those who may not speak the same language as the healthcare professional. Per my experience cultural and language barriers are a big obstacle these families face. This could be because they can …


Emotional Self-Regulation In Children With Autism Spectrum Disorder, Evan Moring May 2024

Emotional Self-Regulation In Children With Autism Spectrum Disorder, Evan Moring

Capstone Projects and Master's Theses

The focus of this project is teaching 2nd and 3rd-grade children with autism spectrum disorder (ASD) how to develop emotional regulation skills. Emotion regulation is the ability to evaluate and change one’s emotional state in the moment. The problem is that these students have difficulty with emotion regulation and frequently experience emotional outbursts. An emotional outburst could be a child throwing a toy across the classroom because the teacher asked them to stay seated at their desk over three times. The child does not realize they cannot throw toys across the classroom. This happens because children with ASD cannot always …


Mental Health And The Well-Being Of Adolescents, Janeice Pamuspusan May 2024

Mental Health And The Well-Being Of Adolescents, Janeice Pamuspusan

Capstone Projects and Master's Theses

This capstone project focuses on adolescents’ mental health and well-being. Before the age of twenty-five 70% of mental health disorders start to develop which is why it’s important to teach adolescents ways to improve their mental well-being along with the signs of mental disorders (Kutcher et al., 2008). According to the World Health Organization, many of those adolescents' mental health conditions go unrecognized or untreated. Those illnesses often go unrecognized and untreated because of the stigma that follows mental health including cultural differences. Because of those differences, many adolescents will go into adulthood still struggling with their mental well-being and …


Strategies To Help Young Children Obtain Healthy Social-Emotional Development, Alma Fuerte-Jauregui May 2024

Strategies To Help Young Children Obtain Healthy Social-Emotional Development, Alma Fuerte-Jauregui

Capstone Projects and Master's Theses

The focal topic of this capstone project is the healthy social-emotional development of low-income preschool and kindergarten children. One of the school districts in East Salinas is the Alisal District, which has a 100% minority enrollment, and a little over 89% of those students are economically disadvantaged (“Overview of Alisal Union,” 2019). A focus on the social-emotional well-being of the students in this age group and community is needed because some of these children have difficulty integrating socially into the school system and struggle to express their feelings or emotions healthily and safely. Strengthening children's capacity to manage emotions and …


Implementing Anti-Bias Curriculum In The Kindergarten Classroom, Ariana Gonzalez May 2024

Implementing Anti-Bias Curriculum In The Kindergarten Classroom, Ariana Gonzalez

Capstone Projects and Master's Theses

The capstone project will be centered on teaching about diversity and inclusion to four to five-year-old children in a predominantly Latino elementary school. There is a lack of cultural, racial, and family representation in the early childhood curriculum which makes it difficult for some students to establish their identity and sense of belonging in school. The lack of diverse representations also makes it difficult to instill compassion, kindness, and empathy in multicultural and other diverse settings. To help with the problem, the installation of an anti-bias curriculum can lead to the creation of a community that supports all dimensions of …


Supporting Preschoolers Social Emotional Development, Gladiola Peinado May 2024

Supporting Preschoolers Social Emotional Development, Gladiola Peinado

Capstone Projects and Master's Theses

This capstone project focuses on the social-emotional regulation of preschoolers (3–5 years old). Many preschool children are struggling to develop social emotional skills when they first enter their preschool setting. Unfortunately, children with poor social emotional learning skills are more likely to have difficulties with peer relationships and with school adjustment, because they are not able to express or recognize emotions (Ferreira et al,. 2021). When children increase their ability to regulate behavior and emotion, they are better at recognizing their own and others’ emotions and intentions, cooperating with one another, and building relationships with peers. In order to address …


Nutrition Among 5th Grade Students, Nicholas Villanueva May 2024

Nutrition Among 5th Grade Students, Nicholas Villanueva

Capstone Projects and Master's Theses

This capstone project focuses on educating 5th grade students about nutrition. Three lessons were presented in a span of two days where students learned terms specified behind a food label. Some terms include Calorie, Carbohydrate, Proteins, Fats, and high sugar foods. Students learned about healthy portion sizes, the five different food groups, and why physical activity is important for your health. With the curriculum presented to the students I hope all students can use these lessons to make healthier decisions when it comes to their food and health. By doing so it can be a start to a healthier lifestyle.


Bullying Behaviors In Middle School Special Education Settings, Maria Teresa Reyes May 2024

Bullying Behaviors In Middle School Special Education Settings, Maria Teresa Reyes

Capstone Projects and Master's Theses

Middle school students with learning disabilities face a higher risk of being targets of bullying compared to their peers without learning disabilities due to challenges in developing social skills. Bullying behaviors peak at the age of 14, potentially inflicting lasting psychological harm and endangering the student's well being into adulthood. The lack of clearly defining bullying leads to uncertainty amongst students on identifying bullying behaviors thus many bullying incidents being unreported by the victims or their peers. For this study, the participants for this project consisted of middle school students aged 10 to 14 years old, grades 6 to 8, …


Developing Communication Skills In Preschool Children, Michelle Ayala May 2024

Developing Communication Skills In Preschool Children, Michelle Ayala

Capstone Projects and Master's Theses

The language and communication development of a preschooler was the main topic of this capstone project. To help and get children ready for kindergarten, these abilities are necessary. It has been shown that preschoolers who have difficulty developing their communication skills will probably face difficulties as they move through their education.


A Revisionist Case Study Of Women’S Capability Approach: Critiquing The U.S. Afghanistan Intervention, Helene Marie Kristensen May 2024

A Revisionist Case Study Of Women’S Capability Approach: Critiquing The U.S. Afghanistan Intervention, Helene Marie Kristensen

Capstone Projects and Master's Theses

This paper explores the impact the United States has as a superpower country with its military intervention in Afghanistan, focusing on the actions taken and the impact it had on women and their status in Afghan society. This article aims to analyse the challenges women face in Afghanistan, ranging from the traditional gender norms to the suppression faced through the Taliban laws and the conflict through enforcement of Western values through intervention. Drawing on Martha Nussbaum’s capability approach, the paper also analyses women’s agency and well-being in Afghanistan in addition to considering critiques of the capability approach in a non-Western …


The Viral Spread Of Xenophobia: Analyzing The Influence Of Far-Right Politics On Anti-Asian Sentiment Expressed On Social Media During Covid-19., Robert F. Arnold Iii May 2024

The Viral Spread Of Xenophobia: Analyzing The Influence Of Far-Right Politics On Anti-Asian Sentiment Expressed On Social Media During Covid-19., Robert F. Arnold Iii

Capstone Projects and Master's Theses

Throughout history, viral outbreaks have frequently led to the emergence of biased and discriminatory attitudes, often targeting populations that deviate from Western norms. These sentiments commonly manifest as xenophobia and racism (Chen, 2020; Chou, 2021). This report serves as an in-depth analysis of the role far-right political phrasing of Covid-19 as the “Chinese Virus,” played in the proliferation of anti-Asian and xenophobic attitudes, expressed on the social media platform X (Twitter). This study also aims to better understand the various different factors that cause followers of far-right politics to engage and believe in anti-Asian sentiment online. Using Integrated Threat Theory …


Strategies For Helping Collegiate Athletes Cope With Mental Health And Financial Issues, Alexis Sanchez May 2024

Strategies For Helping Collegiate Athletes Cope With Mental Health And Financial Issues, Alexis Sanchez

Capstone Projects and Master's Theses

This capstone project focuses on collegiate athletes’ mental health and financial problems and how they can cope with them. The project is founded on the belief that there is an apparent demand for services offering practical coping mechanisms and financial guidance to collegiate students. Thus, the project includes a one-day workshop to equip student-athletes with strategies to manage mental health and financial issues. The workshops will take place on the main campus at California State University Monterey Bay (CSUMB). It was about engaging with a wide range of athletes from across campus and equipping them with convenient tools and support. …


Stabilization Of Interdomain Interactions In G Protein Α Subunits As A Determinant Of Gαi Subtype Signaling Specificity, Tyler J Lefevre, Wenyuan Wei, Elizaveta Mukhaleva, Sai Pranathi Meda Venkata, Naincy R Chandan, Saji Abraham, Yong Li, Carmen W Dessauer, Nagarajan Vaidehi, Alan V Smrcka May 2024

Stabilization Of Interdomain Interactions In G Protein Α Subunits As A Determinant Of Gαi Subtype Signaling Specificity, Tyler J Lefevre, Wenyuan Wei, Elizaveta Mukhaleva, Sai Pranathi Meda Venkata, Naincy R Chandan, Saji Abraham, Yong Li, Carmen W Dessauer, Nagarajan Vaidehi, Alan V Smrcka

Faculty, Staff and Student Publications

Highly homologous members of the Gαi family, Gαi1-3, have distinct tissue distributions and physiological functions, yet their biochemical and functional properties are very similar. We recently identified PDZ-RhoGEF (PRG) as a novel Gαi1 effector that is poorly activated by Gαi2. In a proteomic proximity labeling screen we observed a strong preference for Gαi1 relative to Gαi2 with respect to engagement of a broad range of potential targets. We investigated the mechanistic basis for this selectivity using PRG as a representative target. Substitution of either the helical domain (HD) from Gαi1 into Gαi2 or substitution of a single amino acid, A230 …


A Randomized Trial Of Two Remote Health Care Delivery Models On The Uptake Of Genetic Testing And Impact On Patient-Reported Psychological Outcomes In Families With Pancreatic Cancer: The Genetic Education, Risk Assessment, And Testing (Generate) Study, Nicolette J Rodriguez, C Sloane Furniss, Matthew B Yurgelun, Chinedu Ukaegbu, Pamela E Constantinou, Ileana Fortes, Alyson Caruso, Alison N Schwartz, Jill E Stopfer, Meghan Underhill-Blazey, Barbara Kenner, Scott H Nelson, Sydney Okumura, Alicia Y Zhou, Tara B Coffin, Hajime Uno, Miki Horiguchi, Allyson J Ocean, Florencia Mcallister, Andrew M Lowy, Alison P Klein, Lisa Madlensky, Gloria M Petersen, Judy E Garber, Scott M Lippman, Michael G Goggins, Anirban Maitra, Sapna Syngal May 2024

A Randomized Trial Of Two Remote Health Care Delivery Models On The Uptake Of Genetic Testing And Impact On Patient-Reported Psychological Outcomes In Families With Pancreatic Cancer: The Genetic Education, Risk Assessment, And Testing (Generate) Study, Nicolette J Rodriguez, C Sloane Furniss, Matthew B Yurgelun, Chinedu Ukaegbu, Pamela E Constantinou, Ileana Fortes, Alyson Caruso, Alison N Schwartz, Jill E Stopfer, Meghan Underhill-Blazey, Barbara Kenner, Scott H Nelson, Sydney Okumura, Alicia Y Zhou, Tara B Coffin, Hajime Uno, Miki Horiguchi, Allyson J Ocean, Florencia Mcallister, Andrew M Lowy, Alison P Klein, Lisa Madlensky, Gloria M Petersen, Judy E Garber, Scott M Lippman, Michael G Goggins, Anirban Maitra, Sapna Syngal

Faculty, Staff and Student Publications

Background & aims: Genetic testing uptake for cancer susceptibility in family members of patients with cancer is suboptimal. Among relatives of patients with pancreatic ductal adenocarcinoma (PDAC), The GENetic Education, Risk Assessment, and TEsting (GENERATE) study evaluated 2 online genetic education/testing delivery models and their impact on patient-reported psychological outcomes.

Methods: Eligible participants had ≥1 first-degree relative with PDAC, or ≥1 first-/second-degree relative with PDAC with a known pathogenic germline variant in 1 of 13 PDAC predisposition genes. Participants were randomized by family, between May 8, 2019, and June 1, 2021. Arm 1 participants underwent a remote interactive telemedicine session …


Supporting Career Development For Early- And Mid-Career Professionals Working In The Bipolar Disorder Field: Key Initiatives To Be Implemented By The International Society For Bipolar Disorders Early- And Mid-Career Committee, Katie M Douglas, Sarah H Sperry, Olivia M Dean, Gabriel R Fries, Fabiano A Gomes, Joanna Jiménez Pavón, Emma Morton, Rachel H B Mitchell, Tamsyn E Van Rheenen, Norma Verdolini, Ni Xu, Georgina M Hosang, Rebekah S Huber May 2024

Supporting Career Development For Early- And Mid-Career Professionals Working In The Bipolar Disorder Field: Key Initiatives To Be Implemented By The International Society For Bipolar Disorders Early- And Mid-Career Committee, Katie M Douglas, Sarah H Sperry, Olivia M Dean, Gabriel R Fries, Fabiano A Gomes, Joanna Jiménez Pavón, Emma Morton, Rachel H B Mitchell, Tamsyn E Van Rheenen, Norma Verdolini, Ni Xu, Georgina M Hosang, Rebekah S Huber

Faculty, Staff and Student Publications

No abstract provided.


Biopsychosocial Occupational Therapy Interventions For Complex Regional Pain Syndrome – A Pilot Manuscript, Cinthia Hartman May 2024

Biopsychosocial Occupational Therapy Interventions For Complex Regional Pain Syndrome – A Pilot Manuscript, Cinthia Hartman

UNLV Theses, Dissertations, Professional Papers, and Capstones

Occupational therapists (OTs) have an essential role in the treatment of upper extremity Complex Regional Pain Syndrome (CRPS) in outpatient therapy settings. Occupational therapy (OT) guidelines and research focus treatment on the Budapest Criteria’s biological signs and symptoms. The International Association for the Study of Pain (IASP) now recognizes CRPS as a primary chronic pain condition and not an autonomic disorder, as it was thought to be in the past. This recognition, along with the psychological and social impacts of the condition, highlight the need for updated OT treatment interventions incorporating a biopsychosocial model. Combining evidence-based CRPS OT interventions for …


The Impact Of Educating Interprofessional Healthcare Workers On The Role Of Occupational Therapy In The Cardiac Acute Care Setting, Jennifer L. Taosuvanna May 2024

The Impact Of Educating Interprofessional Healthcare Workers On The Role Of Occupational Therapy In The Cardiac Acute Care Setting, Jennifer L. Taosuvanna

UNLV Theses, Dissertations, Professional Papers, and Capstones

The acute care setting has been a vastly growing practice area for the occupational therapy profession. Occupational therapists assist clients in the acute care setting with activities of daily living retraining and functional transfer training to increase independence. Each client demonstrates a different discharge course from the acute care setting and occupational therapists play a key role in assisting the clients the most appropriate rehabilitative setting. All professionals in the acute care setting work cohesively to provide clients with the best outcome.

The doctoral project explored the importance of interprofessional healthcare worker education about occupational therapy practices in the acute …


Availability And Utilization Of Endoscopic Retrograde Cholangiopancreatography At Children's Hospitals., Sagar J. Pathak, Thomas M. Attard, Matthew Hall, Mustafa Arain, Melvin B. Heyman, Emily R. Perito May 2024

Availability And Utilization Of Endoscopic Retrograde Cholangiopancreatography At Children's Hospitals., Sagar J. Pathak, Thomas M. Attard, Matthew Hall, Mustafa Arain, Melvin B. Heyman, Emily R. Perito

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVES: No study has explored whether availability of endoscopic retrograde cholangiopancreatography (ERCP) is adequate and equitable across US children's hospitals. We hypothesized that ERCP availability and utilization differs by geography and patient factors.

METHODS: Healthcare encounter data from 2009 to 2019 on children with pancreatic and biliary diseases from the Pediatric Health Information System were analyzed. ERCP availability was defined as treatment at a hospital that performed pediatric ERCP during the year of service.

RESULTS: From 2009 to 2019, 37,946 children (88,420 encounters) had a potential pancreatic or biliary indication for ERCP; 7066 ERCPs were performed. The commonest pancreatic diagnoses …


Optimized Scoring Of End-To-End Dosimetry Audits For Passive Motion Management – A Simulation Study Using The Iroc Thorax Phantom, Alex Burton, Mathieu Gaudreault, Nicholas Hardcastle, Jessica Lye, Sabeena Beveridge, Stephen F Kry, Rick Franich May 2024

Optimized Scoring Of End-To-End Dosimetry Audits For Passive Motion Management – A Simulation Study Using The Iroc Thorax Phantom, Alex Burton, Mathieu Gaudreault, Nicholas Hardcastle, Jessica Lye, Sabeena Beveridge, Stephen F Kry, Rick Franich

Faculty, Staff and Student Publications

Dosimetry audits for passive motion management require dynamically-acquired measurements in a moving phantom to be compared to statically calculated planned doses. This study aimed to characterise the relationship between planning and delivery errors, and the measured dose in the Imaging and Radiation Oncology Core (IROC) thorax phantom, to assess different audit scoring approaches. Treatment plans were created using a 4DCT scan of the IROC phantom, equipped with film and thermoluminescent dosimeters (TLDs). Plans were created on the average intensity projection from all bins. Three levels of aperture complexity were explored: dynamic conformal arcs (DCAT), low-, and high-complexity volumetric modulated arcs …


Cross-Vendor Multiparametric Mapping Of The Human Brain Using 3d-Qalas: A Multicenter And Multivendor Study, Shohei Fujita, Borjan Gagoski, Ken-Pin Hwang, Akifumi Hagiwara, Marcel Warntjes, Issei Fukunaga, Wataru Uchida, Yuya Saito, Towa Sekine, Rina Tachibana, Tomoya Muroi, Toshiya Akatsu, Akihiro Kasahara, Ryo Sato, Tsuyoshi Ueyama, Christina Andica, Koji Kamagata, Shiori Amemiya, Hidemasa Takao, Yasunobu Hoshino, Yuji Tomizawa, Kazumasa Yokoyama, Berkin Bilgic, Nobutaka Hattori, Osamu Abe, Shigeki Aoki May 2024

Cross-Vendor Multiparametric Mapping Of The Human Brain Using 3d-Qalas: A Multicenter And Multivendor Study, Shohei Fujita, Borjan Gagoski, Ken-Pin Hwang, Akifumi Hagiwara, Marcel Warntjes, Issei Fukunaga, Wataru Uchida, Yuya Saito, Towa Sekine, Rina Tachibana, Tomoya Muroi, Toshiya Akatsu, Akihiro Kasahara, Ryo Sato, Tsuyoshi Ueyama, Christina Andica, Koji Kamagata, Shiori Amemiya, Hidemasa Takao, Yasunobu Hoshino, Yuji Tomizawa, Kazumasa Yokoyama, Berkin Bilgic, Nobutaka Hattori, Osamu Abe, Shigeki Aoki

Faculty, Staff and Student Publications

Purpose: To evaluate a vendor-agnostic multiparametric mapping scheme based on 3D quantification using an interleaved Look-Locker acquisition sequence with a T2 preparation pulse (3D-QALAS) for whole-brain T1, T2, and proton density (PD) mapping.

Methods: This prospective, multi-institutional study was conducted between September 2021 and February 2022 using five different 3T systems from four prominent MRI vendors. The accuracy of this technique was evaluated using a standardized MRI system phantom. Intra-scanner repeatability and inter-vendor reproducibility of T1, T2, and PD values were evaluated in 10 healthy volunteers (6 men; mean age ± SD, 28.0 ± 5.6 y) who underwent scan-rescan sessions …


Deep Learning-Based Automatic Classification Of Ischemic Stroke Subtype Using Diffusion-Weighted Images, Wi-Sun Ryu, Dawid Schellingerhout, Hoyoun Lee, Keon-Joo Lee, Chi Kyung Kim, Beom Joon Kim, Jong-Won Chung, Jae-Sung Lim, Joon-Tae Kim, Dae-Hyun Kim, Jae-Kwan Cha, Leonard Sunwoo, Dongmin Kim, Sang-Il Suh, Oh Young Bang, Hee-Joon Bae, Dong-Eog Kim May 2024

Deep Learning-Based Automatic Classification Of Ischemic Stroke Subtype Using Diffusion-Weighted Images, Wi-Sun Ryu, Dawid Schellingerhout, Hoyoun Lee, Keon-Joo Lee, Chi Kyung Kim, Beom Joon Kim, Jong-Won Chung, Jae-Sung Lim, Joon-Tae Kim, Dae-Hyun Kim, Jae-Kwan Cha, Leonard Sunwoo, Dongmin Kim, Sang-Il Suh, Oh Young Bang, Hee-Joon Bae, Dong-Eog Kim

Faculty, Staff and Student Publications

Background and purpose: Accurate classification of ischemic stroke subtype is important for effective secondary prevention of stroke. We used diffusion-weighted image (DWI) and atrial fibrillation (AF) data to train a deep learning algorithm to classify stroke subtype.

Methods: Model development was done in 2,988 patients with ischemic stroke from three centers by using U-net for infarct segmentation and EfficientNetV2 for subtype classification. Experienced neurologists (n=5) determined subtypes for external test datasets, while establishing a consensus for clinical trial datasets. Automatically segmented infarcts were fed into the model (DWI-only algorithm). Subsequently, another model was trained, with AF included as a categorical …


Survival Outcomes Of Patients With Her2/Neu-Positive Breast Cancer With Germline Brca Mutations, Fatma Nihan Akkoc Mustafayev, Mihir Amitabh Shukla, Amanda Lanier, Denái R Milton, Angelica M Gutierrez, Stephen K Gruschkus, John E Lewis, Rashmi K Murthy, Banu K Arun May 2024

Survival Outcomes Of Patients With Her2/Neu-Positive Breast Cancer With Germline Brca Mutations, Fatma Nihan Akkoc Mustafayev, Mihir Amitabh Shukla, Amanda Lanier, Denái R Milton, Angelica M Gutierrez, Stephen K Gruschkus, John E Lewis, Rashmi K Murthy, Banu K Arun

Faculty, Staff and Student Publications

Background: Breast cancer (BC) with germline BRCA1/2 mutations and their association with triple-negative BC has been thoroughly investigated. However, some carriers of BRCA1/2 mutations have human epidermal growth factor receptor 2 (HER2/neu)-positive BC, which has a different targeted therapy approach, and data are scarce for this patient population. The authors sought to characterize the clinical characteristics and outcomes of patients with HER2/neu-positive BC who had germline BRCA1/2 mutations.

Methods: This was a retrospective analysis of data from 1099 patients diagnosed with HER2/neu-positive BC who were screened for germline BRCA mutations between 1996 and 2022. Clinicopathologic features and survival rates were …