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“I’M Going To Have To Be Far More Prepared": A Critical Discourse Analysis Of Teacher Candidate Discussion And Projected Teaching Of Literature., Taylor Rose-Dougherty May 2024

“I’M Going To Have To Be Far More Prepared": A Critical Discourse Analysis Of Teacher Candidate Discussion And Projected Teaching Of Literature., Taylor Rose-Dougherty

Electronic Theses and Dissertations

This qualitative dissertation study contributes to conversations around the practical knowledge gap–professional behaviors or practices which are underdeveloped in available research–between critically oriented literacy teacher preparation programs and praxis in early career classrooms. Critical literacy, or engaging with major texts, discourses, and ways of communicating in a culture or context, attempts to locate and disrupt power imbalances and encourage justice-oriented activism. While teacher candidates (TCs) often practice critical literacy in their training programs, they often struggle to facilitate critical literacy instruction in their own classrooms. Using Thematic Analysis (TA) for data reduction and Critical Discourse Analysis (CDA) for data analysis, …


Preserving Archaeology In The Digital Age: Evaluating Strategies For Effective Curation And Database Management., Cenetria Leshun Crockett May 2024

Preserving Archaeology In The Digital Age: Evaluating Strategies For Effective Curation And Database Management., Cenetria Leshun Crockett

Electronic Theses and Dissertations

The “curation crisis” is a dark cloud that consistently looms over the archaeological discipline, affecting the ways we plan, execute, and curate research projects. It is especially prominent within curation facilities and institutions that have the duty to preserve archaeological collections. The development of digital curation presents an avenue through which curators and collection managers can combat the crisis. Digital curation grants collection managers the ability to manage and ensure archaeological collection accessibility. Digital collection databases, particularly, have grown to become a significant component of collection management as it permits collections to be easily preserved, managed, saved, and accessible at …


Educator Perceptions Of Blended Teacher Professional Development: A Case Study Of A Vertically Aligned Virtual Professional Learning Community., Aslean White May 2024

Educator Perceptions Of Blended Teacher Professional Development: A Case Study Of A Vertically Aligned Virtual Professional Learning Community., Aslean White

Electronic Theses and Dissertations

This case study describes the design and enactment of a job-embedded, blended learning professional development plan for teachers to facilitate the collaborative inquiry of a vertically aligned virtual professional learning community. The study is of relevance because it seeks to implement recommendations from recent research on online teacher professional development (Barnett, 2020; Lockee, 2020; Powell & Bodur, 2019) using a framework for support structures designed to engage learners in blended and online learning environments (Philipsen et al., 2019). This qualitative multi-case study examined individual teacher cases using a within-case analysis to create teachers’ profiles to illuminate contextual traits and elucidate …


Multithreaded Applications On The Heterogeneous Research Computing Environment., Sungbo Jung May 2024

Multithreaded Applications On The Heterogeneous Research Computing Environment., Sungbo Jung

Electronic Theses and Dissertations

Bioinformatics is a domain that has experienced rapid research growth in recent years, as evidenced by the increasing number of articles in biomedical databases such as PubMed, which adds over a million publications every year. However, this also poses a challenge for researchers who need to find relevant citations for their work. Therefore, developing efficient indexing and searching methods for text data is crucial for Bioinformatics. One key technique for information retrieval is document inversion, which involves creating an inverted index to enable efficient searching through vast collections of text or documents. This Ph.D. research aims to design the research …


Comparison Of Specific Jaw Position Measurements On A Static And Dynamic Virtual Patient., Payton Lofton May 2024

Comparison Of Specific Jaw Position Measurements On A Static And Dynamic Virtual Patient., Payton Lofton

Electronic Theses and Dissertations

This study aimed to compared the differences in jaw position measurements in protrusive and open/close positions on a static virtual patient created using 3dMD System to those from a dynamic articulation of a virtual patient (MODJAW) as well as measurements between the Cadiax and MODJAW. Six fiducial surface markers were placed on a volunteer subject’s face and dynamic facial scans of protrusive and open/close jaw movement acquired and exported. A CBCT scan was also acquired. The mandible and maxilla were segmented and loaded into Vultus and aligned to the facial scan using the fiducial markers. Results were compared using a …


Conceptualizing An Islamic Character Education Program., Norma Nangju May 2024

Conceptualizing An Islamic Character Education Program., Norma Nangju

Electronic Theses and Dissertations

Character education, specifically faith-based character education, can provide a social, emotional, and academic benefit for students. Through this study, I wanted to take the first step: to design an Islamic character education program collaboratively with all stakeholders of the school. This study used participatory action research as a methodology. The first purpose was for administrators, teachers, parents, students, and community members at an Islamic school in Louisville, KY to collaborate to brainstorm the goals of a character education program at HIRA Institute using the Nominal Group Technique. The second purpose was, based on these goals, how can the strategies of …


A Qualitative Exploration Of Social Capital And Its Influence On Baccalaureate Degree Completion Of First-Generation African American Men At The University Of Louisville., Joseph Marshall Goodman Iii May 2024

A Qualitative Exploration Of Social Capital And Its Influence On Baccalaureate Degree Completion Of First-Generation African American Men At The University Of Louisville., Joseph Marshall Goodman Iii

Electronic Theses and Dissertations

This qualitative dissertation was designed to examine influences which various forms of social capital have on post-secondary degree attainment of first-generation individuals who self-identify as African American men. Additionally, the sample population consisted of Black men who successfully matriculated to earn baccalaureate credentials across differing academic disciplines at a public historically White institution located in the mid-south region of the United States. The research data was extracted from one-on-one, semi-structured interviews using authentic dialogue through open-ended questions. Theoretical paradigms of the study involved a phenomenological approach and an ontological philosophical assumption, integrated with critical theory, critical race theory and social …


Mechanical Property Simulations Of Ploybenzimidazole Membranes., Blake Alexander Clark May 2024

Mechanical Property Simulations Of Ploybenzimidazole Membranes., Blake Alexander Clark

Electronic Theses and Dissertations

This work explores mechanical properties of membranes made of polybenzimidazole utilizing molecular simulations. These simulations researchers to narrow down polybenzimidazole membrane compositions to viable candidates. These simulations are quicker than current purely experimental methods. The increase in throughput would be achieved by eliminating compositions that have unfavorable mechanical properties through preliminary simulation work before moving onto experimental methods. Determining polybenzimidazole membranes’ mechanical properties experimentally would, therefore, allow for researchers to speed up research in areas such as fuel cells and electrolyzers that make use of polybenzimidazole membranes. This study uses Materials Studio and the COMPASS III forcefield to perform these …


Mems Optical Cavities For Low Power Communication., Jacob Schopp May 2024

Mems Optical Cavities For Low Power Communication., Jacob Schopp

Electronic Theses and Dissertations

This thesis discusses the use of MEMS (microelectromechanical systems) optical cavities for use in low power communication. MEMS optical cavities are thin air gaps between an actuated MEMS mirror and a fixed glass encapsulation. By moving the MEMS mirror the reflectivity of the MEMS optical cavity can be changed. This change in reflectivity can be used to transmit information passively by modulating reflected light intensity instead of generating new light using a light source. These MEMS optical cavities are demonstrated using optical fibers for illumination delivery and reflected light collection. In addition to being reflected for communication, the illuminating light …


Suspension Of The Scoundrel: Applying Mental Health Strategies To The Acting Process., Nicholas Wills May 2024

Suspension Of The Scoundrel: Applying Mental Health Strategies To The Acting Process., Nicholas Wills

Electronic Theses and Dissertations

In this thesis, the benefits of having mental health resources, practices and/or coordinators on set or available to help mitigate the mental health challenges that actors may face when portraying complex characters or engaging in emotional experiences while acting, are examined. Actors are required to fully immerse themselves into characters to ensure a full embodiment of the role being played. Without appropriate measures in place to address the actors’ feelings, emotions, and psychological state before, during, and after a production, the actor stands the risk of absorbing the impact of the character with no strategy for how to address the …


Exploring Cultural Enrichment And Musical Development: The Role Of The Brazilian Ensemble In The Jazz Program At The University Of Louisville., Diego Jose Da Silva May 2024

Exploring Cultural Enrichment And Musical Development: The Role Of The Brazilian Ensemble In The Jazz Program At The University Of Louisville., Diego Jose Da Silva

Electronic Theses and Dissertations

This thesis undertakes the multi-dimensional study of the Brazilian ensemble as a powerful source of cultural enrichment and musical development under the jazz pedagogy framework at the University of Louisville. This paper attempts to establish the role of the ensemble in nurturing students' musical skills, promoting cultural understanding, awareness, and a sense of collaboration among the students through observation, interviews, and analysis.


Fingerprinting Cinematic Soundtracks: Examining Identity In Film Music Through Gender And Temporality., Sarah Elizabeth Moser May 2024

Fingerprinting Cinematic Soundtracks: Examining Identity In Film Music Through Gender And Temporality., Sarah Elizabeth Moser

Electronic Theses and Dissertations

This study examines the soundtracks of six Hollywood films and their treatments of two factors of cinematic identity – gender and temporality. Six case studies are used throughout the thesis using an original analytic system I designate as Fingerprinting, which examines film using a five-tier, intersecting system on both the macro and micro level. The gender chapter analyzes Weird Science (1985) and Pretty Woman (1990) in order to demonstrate the utility of the cinematic soundtrack in constructing new frameworks of gender expression within fictional media. The temporality chapter uses four case studies - Easy Rider (1969), Eddie and the Cruisers …


Assessing The Relationship Between Racism In Medicine, Medical Mistrust And Cardiovascular Disease Among Black American Adults., Osayande Agbonlahor May 2024

Assessing The Relationship Between Racism In Medicine, Medical Mistrust And Cardiovascular Disease Among Black American Adults., Osayande Agbonlahor

Electronic Theses and Dissertations

Cardiovascular disease (CVD) persists as the leading preventable cause of death and disability among Black Americans in the United States. Structural and psychosocial factors such as racism have been highlighted as a fundamental cause of persistent cardiovascular health disparities in the U.S. This study examined the associations between racism in medicine, medical mistrust and CVD among Black Americans using the Minority Stress Theory as a theoretical framework. This study evaluates the sociodemographic differences in the quality of care received among Black Americans. Data from the Health Information National Trends Survey, 2022 and the Consumer Assessment of Healthcare Provider and Systems …


Four-Way Cfd-Dem Coupling To Simulate Concrete Pipe Flow: Mechanism Of Formation Of Lubrication Layer, Tooran Tavangar, Masoud Hosseinpoor, Jeffrey S. Marshall, Ammar Yahia, Kamal H. Khayat May 2024

Four-Way Cfd-Dem Coupling To Simulate Concrete Pipe Flow: Mechanism Of Formation Of Lubrication Layer, Tooran Tavangar, Masoud Hosseinpoor, Jeffrey S. Marshall, Ammar Yahia, Kamal H. Khayat

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

This study introduced a four-way CFD-DEM coupling approach to simulate the shear-induced particle migration (SIPM) mechanism leading to formation of the lubrication layer (LL) during concrete pumping. The CFD-DEM simulations considered the coupled effect of concentration (10 %–40 %) and wide size distribution (1–17 mm) of aggregate and rheology of the mortar for forces between the suspending matrix and the particles (and vice versa), as well as force transmission directly between particles (and the pipe wall). The formation of the LL was successfully simulated through a more realistic understanding the SIPM mechanism and rheological evaluation across the pipe with comparable …


Mechanical Properties And Microstructure Of Multi-Materials Fabricated Through A Combination Of Lpbf And Ded Additive Manufacturing Techniques, Christopher J. Bettencourt May 2024

Mechanical Properties And Microstructure Of Multi-Materials Fabricated Through A Combination Of Lpbf And Ded Additive Manufacturing Techniques, Christopher J. Bettencourt

All Graduate Theses and Dissertations, Fall 2023 to Present

This research explores the use of different metals combined through 3D-printing to enhance the performance of materials, with a focus on making heat exchangers more cost-effective for renewable energy. The goal is to replace a costly high-temperature alloy with a more affordable low-temperature alloy, using metal additive manufacturing for its benefits such as less material waste, faster production, reduced weight, and the ability to print entire assemblies in one go. The study delves into a unique combination of two 3D-printing techniques, Directed Energy Deposition and Laser Powder-Bed Fusion, to create a multi-material composed of stainless steel 316L and a nickel-based …


The Effect Of Seed Mix Density And Composition On Wetland Plant Community Assembly In The Great Salt Lake Watershed, Elana Feldman May 2024

The Effect Of Seed Mix Density And Composition On Wetland Plant Community Assembly In The Great Salt Lake Watershed, Elana Feldman

All Graduate Theses and Dissertations, Fall 2023 to Present

Wetlands provide important ecosystem services to society but are in danger across the globe partly due to the spread of invasive species (species that harm humans, the environment, or the economy). One species, Phragmites australis, is a widespread invader across the country, including in the wetlands of the Great Salt Lake and Utah Lake. Phragmites australis spreads widely and quickly outcompetes native species. In places where P. australis has already been removed, seeding wetlands helps block P. australis from returning. Native plants’ ability to prevent invasive species from entering the community is affected by many factors, but two that …


Assessing Impact Of Food Structure On Oral Tribology And In-Vitro Digestion Of Dairy Products, Lamis Ali May 2024

Assessing Impact Of Food Structure On Oral Tribology And In-Vitro Digestion Of Dairy Products, Lamis Ali

All Graduate Theses and Dissertations, Fall 2023 to Present

In this research, we focused on understanding the critical elements impacting consumer experience and the nutritional value of dairy products, specifically their texture, mouthfeel, and protein breakdown in the gastrointestinal tract. Our study aimed to accomplish two main goals. First, we performed analysis of the tribological attributes of various commercially dairy products. The second objective was to investigate the process of disintegration and protein release in selected dairy products.

The study included an assessment of eight dairy products of varied consistencies: solid like cheddar, cheese curd, and parmesan; semi-solid such as cottage cheese, ricotta cheese, and yogurt; and liquid represented …


Do Poor Countries Catch Up To Rich Countries? Structural Change In The World-Economy, 1816-1916, Jared Walker May 2024

Do Poor Countries Catch Up To Rich Countries? Structural Change In The World-Economy, 1816-1916, Jared Walker

All Graduate Theses and Dissertations, Fall 2023 to Present

Do poor countries catch up to rich countries? To answer that question, countries were divided into upper class (core), middle class (semi-periphery), and lower class (periphery) based on degree of industrialization as indicated by primary energy consumption data. Findings indicated twenty-three upward transitions and five downward transitions during the period examined. Asymmetrical upward mobility was understood in the context of geographic expansion of the system. This sufficiently increased the population of the lower class (periphery) to support larger populations in the middle class (semi-periphery) and upper class (core). Nevertheless, probability analysis indicated a stable system characterized by high levels of …


Field Flow Measurements For Pipe Installations With Non-Ideal Conditions, Jake Douglas May 2024

Field Flow Measurements For Pipe Installations With Non-Ideal Conditions, Jake Douglas

All Graduate Theses and Dissertations, Fall 2023 to Present

Accurate flow measurement data is necessary to effectively manage water resources. The purpose of this research is to investigate options to improve field flow measurement by investigating alternatives for calibrating flow meters installed in non-ideal piping. Typically, to accurately measure a flow rate using most types of flow meters, it is recommended that a straight section of pipe be installed immediately upstream and downstream of the flow meter to avoid flow fluctuations at the meter location. However, in many cases, flow disturbances upstream of the meter are unavoidable.

The performance of field flow measurements in non-ideal piping scenarios were studied …


Respiratory Illnesses In Women And Children From Ghana: Problem Identification And Intervention, Stephanie Dale May 2024

Respiratory Illnesses In Women And Children From Ghana: Problem Identification And Intervention, Stephanie Dale

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Rural communities in the upper east region of Ghana currently cook with traditional coal pots that produce increased levels of smoke resulting in rapid fuel consumption, increased air pollution, and high levels of respiratory illness in the women and children who use them. New stoves have been developed that remain similar to the traditional ones in use but are designed to provide a variety of benefits such as lowering the cost of fuel, reducing air pollution, and decreasing rates of respiratory illness in women and children. The purpose of this research study was to identify why women have not begun …


Difference Between The Impact Of Active Social Media Use And Passive Social Media Use On Adolescent Mental Health: An Expanded Literature Review, Lydia Underwood May 2024

Difference Between The Impact Of Active Social Media Use And Passive Social Media Use On Adolescent Mental Health: An Expanded Literature Review, Lydia Underwood

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Background: With the first generation of adolescents being raised with seemingly unlimited access to social media, there is a clear need for research to determine the long-term mental health effects of social media use. Social media use can be categorized into two main categories — active use and passive use. Active use refers to a user posting content and engaging in the media they are viewing. Contrastingly, passive use refers to a user consuming social media content, without engaging in it in ways such as liking or commenting. The aim of this extended literature review was to answer the …


Barriers To Breastfeeding In Low Socioeconomic Populations, Nikki Goldberg, Paige Daws May 2024

Barriers To Breastfeeding In Low Socioeconomic Populations, Nikki Goldberg, Paige Daws

The Eleanor Mann School of Nursing Undergraduate Honors Theses

This literature review assessed and determined common themes among vulnerable populations for the initiation and continuation of breastfeeding habits. The barriers identified were divided into four themes including: lack of support, inflexible employment environment, differences of breastfeeding norms and education, and financial burden. Interventions identified in this literature review were community support programs and the implementation of hospital programs and initiatives to encourage breastfeeding. The need for this research and discussion stems from the sub-optimal infant feeding practices that contribute to infant mortality rates (Gallegos et al., 2020).


Immunotherapy Withdrawal By Step-Down To Mesalamine In Pediatric Patients With Ulcerative Colitis, Reka Szigeti, Richard Kellermayer May 2024

Immunotherapy Withdrawal By Step-Down To Mesalamine In Pediatric Patients With Ulcerative Colitis, Reka Szigeti, Richard Kellermayer

Faculty, Staff and Students Publications

OBJECTIVE: Parents and pediatric patients with ulcerative colitis (UC) who progressed to systemic immunotherapy are concerned about lifelong risks from such treatments. There is limited knowledge about withdrawal of such agents and step-down (SD) to enteral 5-aminosalicylic acid (mesalamine) before transitioning to adult care.

METHODS: We studied nine pediatric cases with moderate to severe UC who after a median of 2.18 years of clinical remission on systemic immunotherapy stepped down to oral mesalamine treatment.

RESULTS: Average follow-up time from SD was 3.49 years. Five patients (55.5%) had sustained remission (without any flare noted) after SD during follow-up. Sustained clinical remission …


Improving Adherence To Clinical Practice Guidelines For Managing Gastric Intestinal Metaplasia Among Gastroenterologists At A Us Academic Institution, Jake Jacob, Valentine Millien, Scott Berger, Ruben Hernaez, Gyanprakash A Ketwaroo, Avegail G Flores, Jason K Hou, Maria E Jarbrink-Sehgal, Natalia I Khalaf, Daniel G Rosen, Hashem B El-Serag, Mimi C Tan May 2024

Improving Adherence To Clinical Practice Guidelines For Managing Gastric Intestinal Metaplasia Among Gastroenterologists At A Us Academic Institution, Jake Jacob, Valentine Millien, Scott Berger, Ruben Hernaez, Gyanprakash A Ketwaroo, Avegail G Flores, Jason K Hou, Maria E Jarbrink-Sehgal, Natalia I Khalaf, Daniel G Rosen, Hashem B El-Serag, Mimi C Tan

Faculty, Staff and Students Publications

BACKGROUND: Clinical guidelines reserve endoscopic surveillance after a gastric intestinal metaplasia (GIM) diagnosis for high-risk patients. However, it is unclear how closely guidelines are followed in clinical practice. We examined the effectiveness of a standardized protocol for the management of GIM among gastroenterologists at a US hospital.

METHODS: This was a preintervention and postintervention study, which included developing a protocol and education of gastroenterologists on GIM management. For the preintervention study, 50 patients with GIM were randomly selected from a histopathology database at the Houston VA Hospital between January 2016 and December 2019. For the postintervention study, we assessed change …


A Biophysically Constrained Brain Connectivity Model Based On Stimulation-Evoked Potentials, William Schmid, Isabel A Danstrom, Maria Crespo Echevarria, Joshua Adkinson, Layth Mattar, Garrett P Banks, Sameer A Sheth, Andrew J Watrous, Sarah R Heilbronner, Kelly R Bijanki, Alessandro Alabastri, Eleonora Bartoli May 2024

A Biophysically Constrained Brain Connectivity Model Based On Stimulation-Evoked Potentials, William Schmid, Isabel A Danstrom, Maria Crespo Echevarria, Joshua Adkinson, Layth Mattar, Garrett P Banks, Sameer A Sheth, Andrew J Watrous, Sarah R Heilbronner, Kelly R Bijanki, Alessandro Alabastri, Eleonora Bartoli

Faculty, Staff and Students Publications

BACKGROUND: Single-pulse electrical stimulation (SPES) is an established technique used to map functional effective connectivity networks in treatment-refractory epilepsy patients undergoing intracranial-electroencephalography monitoring. While the connectivity path between stimulation and recording sites has been explored through the integration of structural connectivity, there are substantial gaps, such that new modeling approaches may advance our understanding of connectivity derived from SPES studies.

NEW METHOD: Using intracranial electrophysiology data recorded from a single patient undergoing stereo-electroencephalography (sEEG) evaluation, we employ an automated detection method to identify early response components, C1, from pulse-evoked potentials (PEPs) induced by SPES. C1 components were utilized for a …


Shocking Financed Emissions: The Effect Of Economic Volatility On The Portfolio Footprinting Of Financial Institutions, Ilmi Granoff, Tonya Lee May 2024

Shocking Financed Emissions: The Effect Of Economic Volatility On The Portfolio Footprinting Of Financial Institutions, Ilmi Granoff, Tonya Lee

Sabin Center for Climate Change Law

Many financial institutions are now calculating and disclosing their financed emissions, a class of metrics enabling these institutions to calculate the greenhouse gas (GHG) emissions associated with investment and lending activities. These institutions have widely adopted the metric to estimate exposure to climate-related financial risk associated with GHG-emitting activities and to provide shareholders and investors a picture of how their financial activity impacts global climate change. Financed emissions metrics, despite widespread adoption, face two key methodological challenges: lack of comparability of outputs within and between portfolios, and vulnerability of calculations to portfolio volatility. Markets are naturally volatile, but the economic …


Climate Change And Human Health: A Synthesis Of Scientific Research And State Obligations Under International Law, Jessica A. Wentz May 2024

Climate Change And Human Health: A Synthesis Of Scientific Research And State Obligations Under International Law, Jessica A. Wentz

Sabin Center for Climate Change Law

This report synthesizes the latest scientific research on the human health effects of climate change and discusses the legal implications of this research, specifically with regards to State obligations under international law. In doing so, the report seeks to provide insights on issues to be analyzed by the International Court of Justice (ICJ) in its upcoming advisory opinion on the legal obligations of States with respect to climate change. It also seeks to enhance the capacity of judges, advocates, and governments to understand these issues in the context of current and future proceedings involving international law obligations related to climate …


In This Issuereview Articleoriginal Articlescase Report May 2024

In This Issuereview Articleoriginal Articlescase Report

Saudi Medical Journal

No abstract provided.


Comparison Of The Genotoxicity Of Propofol And Desflurane Using The Comet Assay In The Lymphocytes Of Patients Who Underwent Lumbar Discectomy: A Randomized Trial, Melike Korkmaz Toker, Basak Altiparmak, Guven Gursoy, Ali Ihsan Uysal, Gulseda Dede, Gulsah Gundogdu, Yavuz Dodurga, Bakiye Ugur May 2024

Comparison Of The Genotoxicity Of Propofol And Desflurane Using The Comet Assay In The Lymphocytes Of Patients Who Underwent Lumbar Discectomy: A Randomized Trial, Melike Korkmaz Toker, Basak Altiparmak, Guven Gursoy, Ali Ihsan Uysal, Gulseda Dede, Gulsah Gundogdu, Yavuz Dodurga, Bakiye Ugur

Saudi Medical Journal

Objectives: To compare the genotoxic effects of desflurane and propofol using comet assay in patients undergoing elective discectomy surgery. Methods: This was a randomized controlled study. Patients who underwent elective lumbar discectomy under general anesthesia with propofol or desflurane were included in the study. Venous blood samples were obtained at 4 different time points: 5 minutes before anesthesia induction (T1), 2 hours after the start of anesthesia (T2), the first day after surgery (T3), and the fifth day following surgery (T4). Deoxyribonucleic acid damage in lymphocytes was assessed via the comet assay. Results: A total of 30 patients, 15 in …


Impact Of Change In The Naples Prognostic Score After Neoadjuvant Chemoradiotherapy On Survival In Esophageal Squamous Cell Carcinoma Patients, Haowen Zhang, Xin Xiao, Siyuan Luan, Xiaokun Li, Shangwei Sun, Yong Yuan May 2024

Impact Of Change In The Naples Prognostic Score After Neoadjuvant Chemoradiotherapy On Survival In Esophageal Squamous Cell Carcinoma Patients, Haowen Zhang, Xin Xiao, Siyuan Luan, Xiaokun Li, Shangwei Sun, Yong Yuan

Saudi Medical Journal

Objectives: To assess the clinical relevance and prognostic value of changes in the Naples prognostic score (NPS) after neoadjuvant chemoradiotherapy (NACR) among esophageal squamous cell carcinoma (ESCC) patients. Methods: We studied 232 locally advanced ESCC patients who received NACR before undergoing esophagectomy retrospectively. Categorizing individuals into the elevated NPS group and the non-elevated NPS group based on the change in NPS after NACR (ΔNPS > 0 or ∆NPS ≤ 0), we examined and compared the clinicopathological characteristics, survival rates, and postoperative complications between these 2 groups (∆NPS = post-NACR NPS - pre-NACR NPS). Results: Results: Out of the 232 patients enrolled, …