Digital Commons Network^™

Potential Rainwater Harvesting Site Selection Using Satellite Data And Geomatics Approaches In Shatt Al-Hillah, Babil Province, Iraq, Atheer Askar Ismail, Basheer S. Jasim, Khalid Qaraghuli, Zulfaqar Sa'adi

Engineering and Technology Journal

Water scarcity remains a major environmental and socio-economic challenge in arid and semi-arid regions, where efficient Rainwater Harvesting (RWH) can be a promising solution in providing adequate water. An integrated approach for site selection of RWH in Shatt al-Hilla Region of Iraq using satellite imagery and geomatics techniques. The Landsat 9 OLI/TIRS data, and a 30-meter spatial resolution Digital Elevation Model (DEM) were used to extract several key indicators, including Soil-Adjusted Vegetation Index (SAVI), Modified Normalized Difference Water Index (MNDWI), Bare Soil Index (BSI), slope, and aspect. Using geographic information system (GIS) weighted overlay analysis (WOA), each factor was weighted …

Experimental Investigation On Compaction And Shear Strength Of Saline Soil Using Granular Additives, Mustafa Hassan Abed, Ali Majid. Al-Kinani

Engineering and Technology Journal

Saline soils are widespread in southern Iraq and are generally characterized by low shear strength and poor compaction behavior, which limits their suitability for engineering applications. This study aims to evaluate the effectiveness of mechanical stabilization using locally available granular materials—subbase, crushed stone, and fine gravel—to improve the compaction properties and shear strength of saline soils. The experimental program included modified Proctor compaction tests conducted in accordance with ASTM D1557 and direct shear tests conducted in accordance with ASTM D6528 on untreated soil and treated soil mixtures prepared with additive contents of 7%, 15%, 30%, and 50% based on the …

Beneficial Investigation Of Sustainable Recycled Waste Plastic In Treating The Consolidation Behavior Of Fine Soil, Aram Mohammed Raheem, Cumaraswamy Vipulanandan, Mohammed Hiwa Abdullrahman, Ali Tariq Omer

Journal of Sustainable Construction Materials and Technologies

Recycled waste plastic is one of the regular garbage utilized as a sustainable material in soil remediation. This study examines the efficacy of utilizing local recycled waste plastic as an ecological quantifiable along with soil containing fine particles to analyze the consolidation behavior. Various recycled waste plastic contents ranging from 2% to 10% were employed experimentally in two patterns where in the first pattern the recycled waste plastic were mixed as dry material with the fine soil particles while in the second pattern a sandwich layer of 10% of the recycled waste plastic was placed in the middle of the …

Enhanced Thermal Energy Storage In Buildings: Impregnation, Leakage, And Environmental Performance Of Organic And Inorganic Pcm Composites, Gökhan Genç, Esra Yılmaz, M. Yusuf Yazıcı

Journal of Sustainable Construction Materials and Technologies

This study experimentally investigates the impregnation and leakage performance of various organic (tobacco, sawdust, bay leaf, black cumin) and inorganic (vermiculite, perlite, bentonite, sepiolite) carrier materials used for phase change material (PCM) integration in building applications. The commercial paraffin-based PCM RT-31 was used as the thermal storage medium. Impregnation and leakage tests were conducted to evaluate the PCM absorption capacity, form stability, and energy storage potential of each carrier. The results revealed that perlite (C = 80%) and bay leaf (C = 78%) exhibited the highest impregnation capacities due to their porous and fibrous structures; however, they also demonstrated significant …

Modeling Of Tensile Stress-Strain Response For Steel Fiber Reinforced Self-Compacting Concretes, Anıl Niş, Nilufer Özyurt, Turan Özturan

Journal of Sustainable Construction Materials and Technologies

Main aim of the research was to further understand self-compacting concrete reinforced with steel fibers (SFR-SCC) behavior and to contribute modeling of the tensile stress-strain diagrams for the standardization of the fiber reinforced materials for structural utilization. Fiber reinforced materials has not been used without structural rebar because of the absence of stress-strain curve in tension required for the structural design codes. Hence, an inverse analysis (multi-layer model) was further modified for various steel fibers to predict tensile stress-strain behaviour. For this purpose, 5 different mixes; control, reinforced with long fibers with 0.5% and 1%, short fiber with 0.5% and …

Development Of Differentiated Learning Assisted By Animated Content In Speaking And Writing Learning For Second Grade Elementary School Students, Winaningsih Winaningsih, Euis Eti Rohaeti, Asep Samsudin

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

Speaking and writing are basic skills that play a crucial role in supporting the academic development of elementary school students. Initial observations in one elementary school indicated that learning was still uniform, did not fully address differences in student abilities, and the use of digital media was still limited. This study aimed to analyze the development process, feasibility, and effectiveness of a differentiated learning model supported by animated content in improving the speaking and writing skills of second-grade elementary school students, as well as to identify barriers faced by teachers and students in its implementation. This study used a Research …

Influence Of Smoking On Mlh1 Gene Polymorphism: Insights Into Colorectal Cancer Incidence, Ali Mohammed Al-Abedi, Rand Muhammed Abdul-Hussein Al-Husseini

Al-Bahir

Background: Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide. The MutL Homolog 1 (MLH1) gene plays a critical role in DNA mismatch repair (MMR). Evidence suggests cigarette smoking increases CRC risk, potentially interacting with genetic factors.

Materials and Methods: This case-control study involved 50 Iraqi CRC patients and 50 age- and gender-matched healthy controls. The PCR-RFLP technique was employed for genotyping the -93G/A (rs1800734) polymorphism. Statistical analysis included Chi-square, Fisher's Exact Test, and logistic regression adjusted for confounders. Hardy-Weinberg Equilibrium (HWE) was assessed in controls.

Results: The frequency of the rs1800734 variant was significantly higher in CRC …

Dual-Action Antibacterial Agents Targeting Biofilm Reduction And Membrane Disruption In Staphylococcus Aureus, Rahmat Folashade Zakariyah, Waliyullahi Akorede Husain, Elohor Precious Samuel, Wonder Olanipekun Oloruntoba, Fatmah Opeyemi Saka, Khalid Ayinde Oyelami, Mariam Temitope Baker

Al-Bahir

Antimicrobial resistance in Staphylococcus aureus is a serious global health problem as the organism rapidly develops resistance against widely used antibiotics. This study sought to investigate the antibacterial and antibiofilm properties of γ-Tocopherol, a natural compound from Ocimum gratissimum, as well as its synergism with 5-hydroxymethylfurfural (5-HMF) against S. aureus. The antibacterial activities and minimum inhibitory concentrations of the compounds were determined using agar diffusion and microbroth dilution methods, respectively. Biofilm reduction was evaluated using 2,3,5-triphenyltetrazolium chloride (TTC) assay and membrane integrity was evaluated using the crystal violet microtiter plate assay and the ion leakage assay. The results …

Techno-Economic And Environmental Analysis Of Wind-Powered Green Hydrogen Production In Nigeria, Ignatius Kema Okakwu, Ayodeji Akinsoji Okubanjo, Samson Oladayo Ayanlade, Akintunde Samson Alayande, Solomon Olanrewaju Giwa, Abraham Olatide Amole, Etinosa Noma-Osaghe, Ajibola Oluwafemi Oyedeji

Al-Bahir

Green hydrogen is becoming a viable option for clean energy, and the need to reduce greenhouse gas emissions has also become a popular sustainable energy source. In this paper, we evaluate the technoeconomic and environmental feasibility of green hydrogen production from wind energy in five Nigerian cities: Kano, Jos, Maiduguri, Ikeja, and Ikorodu. Energy potential from wind energy is estimated by using the Weibull distribution method, and six wind turbines are used to calculate electricity generation and hydrogen production. Economics of wind power are estimated through levelized cost of energy (LCOE), levelized cost of hydrogen (LCOH), payback period (PBP), and …

Evaluating The Efficacy Of Green-Method-Prepared Zinc Oxide Nanoparticles On Gene Expression Of Efflux Pumps In Klebsiella Pneumoniae Bacteria Isolated From Women With Gestational Diabetes, Wissam Qadry Mutaab, Rana J. Shaker

Al-Bahir

Vaginitis is one of the most common women's health problems, and its severity increases in pregnant women with gestational diabetes due to higher susceptibility to infection and increased rates of antibiotic resistance. The research problem: The increasing prevalence of multidrug-resistant isolates of Klebsiella pneumoniae and its association with AcrAB-TolC ejaculation pumps limits treatment efficacy, while the effect of green-method nanoparticles on gene expression of these pumps remains unclear. This paper aimed to detect the acrA and acrB genes in K. pneumoniae isolates and evaluate the effect of zinc oxide nanoparticles prepared with garlic and rosemary extracts on their gene expression. …

Investigating The Optical Qualities Of Aluminum Nanoparticles With Nd:Yag Pulsed Laser Ablation In Liquid Technology, Ban A. Bader, Muna Y. Slewa, Zaid T. Aldabbagh

AUIQ Technical Engineering Science

This research investigated the preparation of aluminum nanoparticles using pulsed laser ablation in liquid (PLAL). Ablation was performed on a metallic target in distilled water using a 532 nm Nd:YAG laser at different laser energies (400, 600, and 800 mJ) with a repetition frequency of 1 Hz and 300 pulses. A change in the solution's color is one of the first indicators of nanoparticle formation. We observed a change in the color of the deionized distilled water from light white to dark white, suggesting the production of aluminum nanoparticles. Furthermore, UV-VIS measurements showed an increase in the material concentration with …

Cover And Contents

Turkish Journal of Medical Sciences

No abstract provided.

Comparison Of Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block And Thoracic Paravertebral Block For Postoperative Analgesia After Breast Surgery: A Prospective Randomized Noninferiority Trial, Mustafa Sirri Kotanoğlu, Musa Zengi̇n, Onur Küçük, Atakan Sezgi̇, İbrahi̇m Topcu, Aras Meti̇n, Zeynep Ersoy, Jüli̇de Ergi̇l

Turkish Journal of Medical Sciences

Background/aim: This noninferiority trial aimed to evaluate whether the serratus posterior superior intercostal plane block (SPSIPB) provides noninferior postoperative analgesia compared with the thoracic paravertebral block (TPVB) after unilateral mastectomy.

Materials and methods: This prospective, randomized, assessor-blinded, parallel-group noninferiority trial enrolled 60 female patients scheduled for elective unilateral mastectomy. Patients received either ultrasound-guided SPSIPB (n = 30) or TPVB (n = 30) with 30 mL of 0.25% bupivacaine before induction. The primary outcome was visual analogue scale (VAS) pain scores (0–100 mm) at rest and during coughing over 24 h. Noninferiority was assessed using the Hodges–Lehmann median difference with 95% …

Comprehensive Geriatric Assessment Identifies Multidimensional Vulnerabilities In Older Adults With Heart Failure, Ci̇han Kiliç, Rengi̇n Demi̇r, Özlem Yilmaz Aykent, Zerri̇n Yi̇ği̇t, Pinar Küçükdağli, Banu Özulu Türkmen, Güli̇stan Bahat, Mehmet Aki̇f Karan

Turkish Journal of Medical Sciences

Background/aim: Heart failure (HF) in older adults is frequently accompanied by geriatric syndromes that remain unrecognized in conventional cardiac evaluations. The vulnerabilities of older adults with and without HF in terms of muscle strength, physical performance, functional capacity, frailty, nutritional status, cognition, mood, anxiety, polypharmacy, and comorbidity were investigated using comprehensive geriatric assessment (CGA).

Materials and methods: A cross-sectional study was conducted in two academic outpatient clinics, enrolling 420 adults aged ≥60 years, including 92 (21.9%) with HF. Data included sociodemographic characteristics, anthropometric measurements, and CGA parameters: handgrip strength, the Five-Times Sit-to-Stand Test (FTSST), the Short Physical Performance Battery (SPPB), …

Multiple Organ Dysfunction Syndrome In Pediatric Colchicine Poisoning: A National Cohort Study From Türkiye, Faruk Eki̇nci̇, Di̇nçer Yildizdaş, Ozden Özgür Horoz, Hayri̇ Levent Yilmaz, Sevcan Bi̇len, İlker Ünal, İkbal Türker, Esra Şevketoğlu, Ni̇hal Akçay, Agop Çitak, Güntülü Şik, Tanil Kendi̇rli̇, Merve Havan, Murat Kangin, Mehmet Nur Talay, Nazi̇k Yener, Hati̇ce Albayrak, Edi̇n Botan, Utku Özer, Arzu Oto, Gürkan Bozan, Muhterem Duyu, Başak Nur Akyildiz, Nai̇me Gökay, Eli̇f Çeli̇k, Çapan Konca, Mutlu Uysal Yazici, Oğuz Dursun, Feyza İnceköy Gi̇rgi̇n, Hati̇ce Feray Ari, İlknur Arslan, Murat Özkale, Özlem Sandal, Merve Misirlioğlu, Hali̇l Keski̇n, Sadik Kaya, Arda Kilinç, Ferhat Sari, Fati̇h Akin, Ayşe Aşik, Ibrahi̇m Bi̇ngöl, Eda Turanli, Merve Boyraz, Ener Çağri Di̇nleyi̇ci̇, Mehmet Aki̇f Dündar, Selver Ceren Özcan, Aygül Kaya Akilli, Emi̇ne Akkuzu, Nazan Ülgen Tekerek, Ni̇lüfer Öztürk, Emrah Gün, Yasemi̇n Özkale, Nuretti̇n Onur Kutlu, Zeynelabi̇di̇n Öztürk

Turkish Journal of Medical Sciences

Background/aim: Colchicine poisoning has been associated with systemic toxicity, multiple organ dysfunction syndrome (MODS), and mortality. In the present study, the demographic, clinical, and laboratory characteristics of pediatric colchicine poisoning cases and the incidence of organ failure are investigated to identify potential risk factors associated with MODS.

Materials and methods: Included in this retrospective multicenter cohort study were pediatric patients admitted to 28 tertiary-care pediatric intensive care units with a diagnosis of colchicine poisoning. Demographic data, clinical and laboratory findings, and clinical outcomes were extracted from medical records. MODS was defined as dysfunction involving at least two organ systems. Multivariable …

Timing Of Kirschner Wire Removal In Pediatric Supracondylar Humerus Fractures: Is Early Removal A Safe And Effective Option?, Mustafa Kemal Yeni̇dünya, Si̇nan Yüksel, İbrahi̇m Faruk Adigüzel, Serhat Di̇nç, Önder Ersan

Turkish Journal of Medical Sciences

Background/aim: The optimal timing of Kirschner wire removal following the surgical treatment of pediatric supracondylar humerus fractures remains controversial. This study aimed to compare the clinical and radiographic outcomes of early versus late K-wire removal and to contribute to the standardization of the timing of pin removal in pediatric patients.

Materials and methods: This retrospective study included 90 pediatric patients (aged 4–14 years) treated with closed reduction and percutaneous pinning for Gartland type III and IV supracondylar humerus fractures. Patients were grouped according to the timing of pin removal as early (postoperative days 21–28, n = 40) or late (after …

Common Femoral Vein Wall Thickness As A Supportive Imaging Marker In The Differential Diagnosis Of Behçet’S Uveitis, Seda Kutluğ Ağaçkiran, Esra Kardeş, Abdulbaki̇ Ağaçkiran, Haner Di̇reskeneli̇, Fatma Ali̇baz-Öner

Turkish Journal of Medical Sciences

Background/aim: Ocular involvement is a major cause of morbidity in Behçet’s disease (BD), and its diagnosis may be challenging, particularly for patients with isolated ocular manifestations or incomplete fulfillment of diagnostic criteria. Increased common femoral vein (CFV) wall thickness measured by Doppler ultrasonography (US) has previously been shown to be a sensitive and specific marker for systemic BD. This study aimed to evaluate whether CFV wall thickness measurement may serve as a supportive tool in distinguishing Behçet’s uveitis (BU) from other forms of inflammatory uveitis.

Materials and methods: This retrospective study included 45 patients with BU fulfilling the International Study …

Alterations In Gut Microbiota Composition In Adult Patients With Familial Mediterranean Fever: A Pilot Case–Control Study, Nazi̇fe Şule Yaşar Bi̇lge, Vicente Pérez Brocal, Ti̇muçi̇n Kaşi̇foğlu, Uğur Bi̇lge, Ni̇lgün Kaşi̇foğlu, Andres Moya, Ener Çağri Di̇nleyi̇ci̇

Turkish Journal of Medical Sciences

Background/aim: Although familial Mediterranean fever (FMF) is a monogenic disease, recent evidence suggests that the gut microbiota may play a role in its pathogenesis or phenotypic expression. We conducted a pilot exploratory study to evaluate the intestinal microbiota composition in patients with FMF and compare it to that of healthy controls.

Materials and methods: In this prospective cohort study, 10 adult patients with FMF receiving colchicine and 10 age- and sex-matched healthy controls were enrolled. Fecal samples were collected and stored at –80 °C until DNA extraction. The V3–V4 region of the 16S rRNA gene was amplified and sequencing was …

Hla Allele And Haplotype Diversity In Central Anatolia: A Comparative Analysis Of Donors And Transplant Candidates Across Six Hla Loci (Hla-A, Hla-B, Hla-C, Hla-Drb1, Hla-Dqb1, And Hla-Dpb1), Emel Yantir, Eren Gündüz, Ertuğrul Çolak

Turkish Journal of Medical Sciences

Background/aim: Human leukocyte antigen (HLA) polymorphisms play a central role in immune recognition, disease susceptibility, and transplant success. The distribution of HLA alleles and haplotypes varies among ethnic and geographic populations. Despite several regional studies conducted in Türkiye, large-scale and comprehensive investigations comparing HLA profiles between healthy individuals and transplant candidates remain limited. The aim of this study was to compare the distribution of HLA profiles among donors, hematopoietic stem cell transplantation (HSCT) candidates, and solid organ transplant candidates.

Materials and methods: A total of 8472 individuals were included in the study, comprising 6422 donors and 2050 transplant candidates. HLA …

Omega-3–Rich Fish Oil Lipid Emulsions Significantly Prevent Sepsis-Driven Mesenteric Hypoperfusion And Multi-Organ Injury In Murine Models, Gökşen Öz, Esi̇n Özçelebi̇, Ayşe Yeşi̇m Göçmen, Cenk Sükmensüer, Selma Yildirim, Arzu Topeli̇, Alper Bektaş İski̇t

Turkish Journal of Medical Sciences

Background/aim: Parenteral feeding is used in critically ill patients when enteral nutrition is inadequate or intolerable, and the gastrointestinal tract is not functioning properly. Lipid emulsions play a major role in parenteral nutrition because they supply necessary fatty acids and a high-calorie density. We investigated the effects of parenteral lipid emulsions on mesenteric perfusion, inflammation-induced oxidation, and organ damage in lipopolysaccharide-induced mice endotoxemia model.

Materials and methods: In septic mice, organ damage induced by lipopolysaccharide was assessed by histopathology and biochemical examination. Additionally, an ultrasonic blood flowmeter was used to measure the impact of lipid emulsions on mesenteric blood flow. …

Kin A487: Administration & Supervision In Kinesiology, T. J. Miller

Publications

Critiques and evaluates the technical, leadership, and supervisory skills necessary to safely and effectively administer kinesiology-related programs. Presents theoretical, practical, and research perspectives. Special Note: Community engagement & Interviews will be required.

Book Review - Violent Impacts: How Power And Inequality Shape The Concussion Crisis, Samuel M. Clevenger

Global Sport Business Journal

Kathryn Henne and Matt Ventresca’s Violent Impacts critically examines how narratives surrounding CTE, TBI, and the concussion crisis are constructed across sport, the military, law, media, and science. Drawing on intersectional feminism and science and technology studies, the authors show how dominant concussion discourses privilege the experiences of White male athletes while marginalizing other groups. Based on extensive fieldwork, the book makes an important contribution by exposing representational inequalities and highlighting the intersectional gender politics of concussion research and public debate.

Extracurricular Video Game Use And Academic Achievement: A Systematic Literature Review, Christina Hartman, Theo Makanoa, Lucas Thoms, Aidan Lowry, Kaleb Chandler

English Student Research

A good deal of research exists on the relationship between student use of video games outside the classroom and academic achievement. Our systematic review aims to identify what patterns exist across research conducted in the last 20 years. We examined 62 research studies that dealt with academic achievement and extracurricular video game use and found that most studies identify a negative association between the two. However, this isn’t the case for all students. We identified three important variables (the amount of time spent playing video games, the time of day or week spent playing, and the age of the students) …

New National Publication Gives Guidance To Teachers On Ai, Clara Turnage

University of Mississippi News

OXFORD, Miss. – With artificial intelligence tools available on every phone, laptop and tablet, higher education has struggled to implement consistent recommendations for how and when AI can be used. A new national guide seeks to change that.

From Innovation To Speculation: Ai And The Magnificent Seven, Rerotlhe B. Basele, Peter C. B. Phillips, Shuping Shi

Cowles Foundation Discussion Papers

The AI boom has driven the Nasdaq and the Magnificent Seven tech stocks to record highs. But how much do these new records reflect underlying value, how much is speculation, and how vulnerable are these stocks and the wider market to a major downturn? Our evidence and analyses show clear signs of bubble exuberance in most of these stocks, concentrated in a few names like Nvidia, leading to latent risks for investors who assume their index funds are safely diversified and supported by wider economic fundamentals.

If Pets Are Family: Pet Loss And The Need For Grief Equity In One Health, Michele L. Whitney

Journal of One Health Systems

One Health frameworks increasingly recognize pets as integral to human health and well-being. However, these models often overlook the health and equity implications of pet loss. Culturally mediated grief experiences following pet bereavement represent a critical grief equity gap in One Health systems. Drawing on findings from a qualitative study of African American adults who experienced pet loss, along with existing literature, this Viewpoint highlights how pet loss is not only an emotional experience but also a socially structured one shaped by cultural norms, social recognition, and access to support. These dynamics contribute to inequities in how grief is experienced …

Adding 3,4-Methylenedioxy-Α-Cyclohexylaminopropiophenone To A Standard Operating Procedure (Sop) For Identifying Synthetic Cathinones Using Gas Chromatography-Mass Spectrometry, Napassawon Timpratoom

ETDs from 2020-2029

Synthetic cathinones were identified as new psychoactive substances (NPS) in the early warning advisory system by the United Nations Office on Drugs and Crime (UNODC). Synthetic cathinones have been commonly referred to as bath salts, which offered “legal highs” because they were not explicitly scheduled. These compounds were detected dur-ing the screening process in casework and required internal validation for confirmation. 3,4-methylenedioxy-α-cyclohexylaminopropiophenone was the target analyte for this study. It was alternatively named N-cyclohexyl methylone and “cyputylone." The aim of the study was to validate 3,4-methylenedioxy-α-cyclohexylaminopropiophenone into a Standard Operating Procedure (SOP) for identifying synthetic cathinones using gas chromatography/mass spectrometry …

Clinical, Hormonal, And Treatment Outcomes In 247 Patients With Acromegaly: A Single Tertiary Center Experience, Ümran Gül, Beki̇r Uçan, Hayri̇ Bostan, Hakan Düğer, Hayri̇ Kertmen, Caner Ünlüer, Hali̇l Durantaş, Oğulcan Boz, Ceren Karaçalik Ünver, Burak Menekşe, Sema Hepşen, İlknur Öztürk Ünsal, Mustafa Özbek, Erman Çakal, Muhammed Kizilgül

Turkish Journal of Medical Sciences

Background/aim: This study aimed to evaluate the demographic, clinical, and hormonal characteristics; comorbidities; surgical pathology; treatment modalities; and long-term clinical outcomes of patients diagnosed with and managed for acromegaly at our tertiary referral center over a 15-year period.

Materials and methods: Between 2010 and 2024, 247 patients with acromegaly were evaluated. Diagnosis and biochemical remission were determined according to the 2024 Acromegaly Consensus Criteria.

Results: The median follow-up duration was 8 years (IQR: 3–14). At the time of diagnosis, the most frequent pituitary hormone deficiency was secondary adrenal insufficiency, present in 17.8% of patients. The most common comorbidities were hypertension …

D-Methionine Improves Spatial Navigation And Attenuates Oxidative Stress And Amyloid Pathology In A Sex-Specific Manner., Mackenzie R Peck, Jenelle E Chapman, Tiarra Hill, Kathleen Quinn, Erol D Ikiz, Angel Lopez, Erin R Hascup, Chilman Bae, Kevin N Hascup

Articles

Background

Oxidative stress and maladaptive neuroimmune activation contribute to cognitive decline in Alzheimer's disease (AD) and represent therapeutic targets beyond amyloid-centered approaches.

Objective

To determine whether oral D-methionine (D-Met), a redox-active amino acid, reduces amyloid pathology and lipid peroxidation and confers disease-modifying benefits in AD models.

Methods

Male and female APP/PS1 and APP^NL−Fmice with advanced AD pathology received oral D-Met or vehicle. Behavioral assessments included locomotor activity and hippocampal-dependent spatial learning and memory. Amyloid burden, lipid peroxidation, peripheral metabolic, and inflammatory markers, and hippocampal microglial phenotypes were evaluated.

Results

D-Met did not alter locomotor or exploratory behavior but …

Association Of Vitamin D, Oxidative Stress Markers, And Hormonal Factors With Male Infertility: A Case-Control Study In Pakistan, Muhammad Tayyab Ihsan, Ayesha Ali Malick, Sher Khan, Sher Khan, Muhammad Tahir Khan, Haq Nawaz Khan, Rehana Rehman

Turkish Journal of Medical Sciences

Background/aim: Infertility impacts around 15% of couples worldwide, with male factors accounting for approximately 50% of cases. Despite this significant share, male infertility remains understudied, particularly in developing nations such as Pakistan. The present study explores the association between male infertility and seminal plasma concentrations of oxidative stress markers, inhibin B, and vitamin D, along with their relationship with sperm parameters.

Materials and methods: The dataset of the study consisted of seminal plasma levels from 30 fertile and 60 infertile males. Total antioxidant capacity (TAC), Vitamin D, malondialdehyde (MDA), 4-hydroxynonenal (4-HNE), lipid peroxide (LPO), superoxide dismutase (SOD), and inhibin B …