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Anoxia Tolerant Dna Replication Is Supported By Atr Kinase In The Annual Killifish Austrofundulus Limnaeus, Riley Roth-Carter, Erin Helms, Joshua C. Saldivar, Jason Podrabsky

Biology Faculty Publications and Presentations

Hypoxia and anoxia suppress cell proliferation due to an increase in replication stress and activation of DNA damage checkpoints. Embryos of the annual killifish Austrofundulus limnaeus tolerate prolonged anoxia, indicating improved genomic stability under oxygen starvation. We investigated the cell cycle regulation of the anoxia tolerant killifish embryonic cell line PSU-AL-WS40NE during anoxia. Live-cell imaging confirms continued proliferation of WS40NE cells for the first 24 h of anoxia with minimal cell death. Fluorescence imaging shows that cells accumulate in G1 after the first day in anoxia with a rapid entry into S phase upon reoxygenation. Pharmacological inhibition shows a reliance …

Letter From The Editor

Notre Dame Journal of International & Comparative Law

No abstract provided.

Volume 16 Issue 3 - Full Issue

Notre Dame Journal of International & Comparative Law

No abstract provided.

From Mandela To Meta: Democratization Of The Right Of Publicity, Persona, And Image Rights In Cyberspace, Frederick W. Mostert, Lea Leisure

Notre Dame Journal of International & Comparative Law

No abstract provided.

Low-Dose Multi-Walled Carbon Nanotubes Are Non-Inflammatory Alone But Amplify Lipopolysaccharide-Induced Cytokine Responses In A549 Lung Epithelial Spheroids, Jian Liu, Li Zeng, Wondwossen Abate, Simon K. Jackson

School of Biomedical Sciences

Background – Airborne pollutants comprise biological agents such as lipopolysaccharide (LPS) and engineered nanomaterials, including carbon nanotubes (CNTs), which are increasingly prevalent in industrial and consumer applications. Although the pulmonary toxicity of high-dose CNT exposure is established, the inflammatory consequences of low-dose, non-cytotoxic CNT exposure, particularly in combination with other aerosols, remain poorly understood. Methods – We investigated cytotoxicity and proinflammatory responses to multi-walled CNTs in three-dimensional A549 human epithelial spheroids, compared with A549 monolayers and MM6 monocytes. Cells were exposed to two CNTs differing in diameter (CNT1: 7–15 nm; CNT2: 110–170 nm), alone or combined with LPS. Cell viability …

Exploring Factors Associated With High Frequency Emergency Department Use By Children And Young People: A Retrospective Cohort Study, Akshay Kumar, Rebecca M Simpson, Kerryn Husk, Graham D Johnson, Chris Burton

Peninsula Medical School

Objective To explore drivers of high frequency emergency department (ED) use by children and young people, particularly among those attending EDs most often.Design A population-based retrospective cohort study using routinely collected linked healthcare data.Setting EDs in the Yorkshire and Humber region of the UK.Patients 288 545 children and young people aged 17 and under making at least one ED attendance in the year period 1 April 2016 to 31 March 2017.Main outcome measures ED attendances made by individuals in the year period.Results Of the 288 545 distinct children and young people making at least one attendance to an ED, 27 …

Correctional Officers' Perceptions Of Inmate Suicide In Florida State Prisons, Chrishelle Robbins

Walden Dissertations and Doctoral Studies

Correctional officers are responsible for the care, custody, safety, and supervision of inmates within jails, prisons, and correctional institutions. They face many hardships within a prison setting including inmate suicides. The purpose of this qualitative study was to explore and understand the perceptions of Florida state correctional officers who have experienced inmate suicide firsthand. This study was formulated using the transcendental, descriptive phenomenology approach and addressed the study’s research questions. Participants included nine Florida state certified correctional officers who witnessed an inmate suicide. Participants were selected using purposive snowball sampling. Interviews were scheduled and conducted via ZOOM or by telephone …

The Impact Of Super Political Action Committee Spending On Abortion Legislation In A Post-Dobbs Era, Jeni Atchley

Walden Dissertations and Doctoral Studies

Super political action committee (Super PAC) spending has become a prominent feature of U.S. elections, yet limited research had examined how independent expenditures related to electoral success in competitive U.S. House races and whether that relationship varied by candidates’ abortion policy positions in the post-Dobbs era. Prior research has shown that Super PAC independent expenditures expanded sharply after Citizens United and can influence candidate visibility in competitive races, yet findings on whether that spending translates into electoral success have been mixed, and few studies had examined it in relation to candidates' abortion positions after Dobbs. The purpose of this correlational …

Subscribe, Follow, Save: Podcast Preservation In The Platform Era, Ben Pettis, Jeremy Morris

Rhetoric and Communication Studies Faculty Publications

Podcasting has produced a glut of cultural content. Collecting and saving these sounds for future study, however, remains challenging. This article asks: “How are recent developments in the platformization of podcasting threatening the ability of users and researchers to save, study, and sustain podcasts and the cultural insights they offer?” To answer, we focus on a podcast preservation project, PodcastRE.org, and discuss strategies for creating an (un)stable repository for future studies of podcasting. While new developments challenge preservation efforts, they also offer archivists opportunities to prioritize the cultural significance of podcasts, rather than the economic motives of the podcast industry …

Deciphering The Association Of Fasting Blood Glucose With Gamma-Glutamyl Transferase And Uric Acid: A Cross-Sectional Study In A Tertiary Care Hospital In South India, Anbalagan Anithasri, Rajagambeeram Reeta, Velmurugan Hasini

Sultan Qaboos University Medical Journal

Objectives: Fasting hyperglycaemia (FHG) in insulin resistance is due to oxidative stress wherein gamma-glutamyl transferase (GGT) and uric acid (UA) are known to impair insulin secretion from pancreatic beta cells due to their pro-oxidant action and their role in metabolism of antioxidant glutathione. This study aims to determine the association of GGT and UA with FHG and its role in predicting the onset of prediabetes. Methods: This cross-sectional study was conducted in Government Villupuram Medical College, Villupuram, India, from July to December 2023. Individuals in the age range of 25–65 years attending the master health check-up clinic were included. …

The Hidden Net Cost Of Data Center Construction And Operation For Household Service Pricing, Arezou Shafaghat, Mikhail Klimenko, Da Hu, Ali Keyvanfar

Faculty Articles

The rapid expansion of artificial intelligence (AI) is accelerating data center construction and creating downstream implications for households. This study examines how AI-era data center costs (comprising construction, energy, water, grid upgrades, cooling, and lifecycle management) move through service supply chains and affect household prices in healthcare, transportation, education, banking, and commerce. It also considers the productivity and welfare benefits that AI may transmit. This study identifies four pass-through channels: utility-rate socialization of energy costs, cloud-platform pricing, sectoral pass-through from AI-adopting industries, and indirect effects through supply chains and labor markets. It introduces the AI-inflated net good basket, defined as …

The Use Of Breathing Meditation With Bipoc Trauma Survivors, Keerthi Sundaramurthy

Doctoral Dissertations

There is a growing body of evidence supporting the use of mindfulness-based practices to reduce psychological distress. Although interest in mindfulness-based care is growing, studies investigating virtual interventions for BIPOC trauma survivors remain limited. The goal of this study was to evaluate the effects of a breathing meditation intervention on mental health outcomes in a sample of trauma-exposed BIPOC adults, using a randomized post-test only design. Participants in the intervention group were asked to complete a 10-minute box breathing meditation daily for four weeks. Quantitative analyses revealed that those in the intervention group reported significantly lower symptoms of anxiety and …

The Tagmatized Echinoderm, Richard L. Turner

Ocean Engineering and Marine Sciences Faculty Publications

Synopsis Tagmosis is a derived condition of metamerism in annelids, arthropods, and chordates in which groups of adjacent segments are modified to perform specific functions. Examples are the clitellum of earthworms, the carapace of lobsters, and the sacrum of tetrapods, to mention a few. The argument is advanced here that examples of tagmosis are not hard to find among echinoderms, a fourth major group of metameric animals; but the degree of tagmosis is weak in most cases. The first few segments of the axial skeleton are often conjoined as a perioral tagma (e.g., the jaws and other parts of the …

Co-Designing Translanguaging-Informed Transformative Socioemotional Learning With Bilingual Kindergarten Teachers In Colombia, Catherine Restrepo-Widney

Electronic Theses and Dissertations 2020 - Present

Emergent bilingual children enter early childhood classrooms with rich, dynamic linguistic repertoires that span languages, cultural practices, and ways of knowing. Socioemotional learning (SEL) often fails to meaningfully incorporate children’s linguistic and cultural repertoires, reflecting critiques that many SEL frameworks privilege individualistic, culturally narrow competencies that may marginalize learners from diverse backgrounds. This is particularly consequential in early childhood dual language bilingual education (DLBE), where children's heritage languages are central to authentic emotional connection and identity development, and where empirical models for culturally sustaining SEL remain limited. Through a participatory design research approach structured around iterative cycles of collaborative inquiry, …

The Effect Of Doping In Ferroelectric Hafnium Oxide, Adedamola David Aladese

Electronic Theses and Dissertations Archive

Ferroelectric hafnium oxide (HfO2) has emerged as a promising material for next-generation non-volatile memory and computing technologies because of its compatibility with complementary metal-oxide-semiconductor (CMOS) processing, scalability, and robust ferroelectricity. However, the atomistic mechanisms governing ferroelectric phase stabilization, defect interactions, and polarization switching remain incompletely understood, limiting the rational design of high-performance HfO2-based devices. This dissertation employs first-principles density functional theory calculations to establish atomistic design principles for engineering ferroelectricity in HfO2 through strain, dopant incorporation, oxygen-vacancy engineering, and multivalent defect chemistry. The effects of strain orientation, yttrium (Y) doping, and oxygen vacancies on ferroelectric phase stability were first investigated. …

When Leadership Is Denied: A Phenomenological Study Of Women's Lived Experiences Of Promotion Rejection In The Pakistani Fashion Industry, Atif Bilal, Faiza Majid, Shumaila Zeb, Saqlain Raza, Aliya Abdul Hayee, Wali Ur Rehman

Plymouth Business School

Despite the growing presence of women in creative and leadership roles within the fashion industry, many continue to face barriers to leadership progression. Leadership rejection remains a critical yet underexplored experience that can significantly affect women's professional identity and aspirations. The research aims to explore the lived experiences of women in the fashion industry who perceive being rejected from leadership positions due to discrimination. Using a qualitative, phenomenological approach, 13 semi-structured interviews were conducted with women in the fashion industry of Pakistan. Interpretative Phenomenological Analysis guided data collection and analysis, allowing for a rich exploration of meaning-making processes. The study …

Climate Change, Governance Failure, And Violent Insurgency In Cabo Delgado, Hala Thabet

All Works

Contemporary literature increasingly links rising levels of armed violence in several African countries to the repercussions of climate change, particularly long-term environmental stresses such as the deterioration of agricultural livelihoods, resource scarcity, and recurrent climate shocks. However, this study argues that the relationship between climate change and violence is not an inevitable causal one, but can be understood as the result of the intersection of the failure of the post-independence nation-building project and the impacts of climate change on livelihoods and economic security. In Cabo Delgado province, northern Mozambique, repeated climate shocks and the resulting deterioration of coastal agriculture and …

Impact Of Non-Selective Beta-Blockers On Acute Kidney Injury Outcomes In Patients With Decompensated Cirrhosis, Simone Incicco, Kavish R Patidar, Adrià Juanola, Ann T Ma, Anna Barone, Anand V Kulkarni, José Luis Pérez Hernández, Sumeet K Asrani, Brian Wentworth, Carlo Alessandria, Nadia Abdelaaty Abdelkader, Yu Jun Wong, Qing Xie, Nikolaos T Pyrsopoulos, Sung-Eun Kim, Yasser Fouad, Aldo Torre, Eira Cerda Reyes, Javier Díaz-Ferrer, Rakhi Maiwall, Douglas A Simonetto, Maria Papp, Eric S Orman, Giovanni Perricone, Cristina Solé, Christian M Lange, Alberto Queiroz Farias, Gustavo Pereira, Sebastian Marciano, Paolo Caraceni, Thierry Thévenot, Nipun Verma, Jeong Han Kim, Julio D Vorobioff, Jacqueline Cordova-Gallardo, Vasilisa R Grechishnikova, Raoel Maan, Juan Pablo Roblero, Claudio Toledo, Stefania Gioia, Eduardo Fassio, Mónica Marino, Puria Nabilou, Victor Vargas, Manuela Merli, Luciana Lofego Goncalves, Liane Rabinowich, Aleksander Krag, Lorenz Balcar, Adrian Gadano, Francois Durand, Shiv K Sarin, Pere Ginès, Paolo Angeli, Elsa Solà, Salvatore Piano, International Club Of Ascites Global Aki Team

Faculty, Staff and Students Publications

Background & aims: Non-selective beta-blockers (NSBBs) are widely used to prevent decompensation in cirrhosis. Guidelines recommend discontinuing NSBBs in patients with cirrhosis and acute kidney injury (AKI), although this recommendation is based largely on expert opinion and limited evidence. We evaluated the impact of NSBB use on AKI outcomes in patients with cirrhosis.

Methods: This multicenter study enrolled patients hospitalized for decompensated cirrhosis and AKI. Data on NSBB treatment, including type, dose, and continuation, discontinuation, or tapering, were collected. Outcomes were compared between patients receiving and not receiving NSBBs and between those who discontinued/tapered and those who did not. Inverse …

Bar-And-Hinge Model For Elasto-Plastic Origami Analysis, Yansong Tang, Yeqi Chu, Yue Mei, Yi Zhu, Ke Liu

Michigan Tech Publications

Origami-inspired structures are attracting considerable attention in engineering owing to their ability to facilitate intricate deformations and deployable configurations. However, accurately simulating their mechanical behaviour under realistic conditions involving permanent deformations and energy dissipation remains a significant challenge. In this study, we present an elasto-plastic formulation based on the nonlinear bar-and-hinge model for non-rigid origami simulation. We integrate rate-independent elasto-plastic constitutive models for both the hinges and the bars, enabling tunable representation of both elastic and plastic deformations in origami structures. The formulation employs a return mapping algorithm to ensure consistency with yield conditions checked at each incremental time step, …

Achieving Low-Carbon Buildings Through Advancing Concrete Materials And Automated Construction: A Review, Thanh Ha Ngo, Hai Hoang Khieu, Yingyan Zhang, Quang Tran, Phuong Tran

Michigan Tech Publications

The construction industry is a major contributor to global carbon emissions and faces urgent demands to align with net-zero targets through targeted material selection, manufacturing, and construction methods. Conventional concrete production contributes significant CO2 emissions, necessitating innovative approaches to reduce embodied and operational carbon. This scoping review examines advances in low-carbon concrete production, automated construction methods, their integration and practical applications. The review is based on literature published between 2015 and 2025, collected from Elsevier ScienceDirect and additional sources, focusing on low-carbon concrete materials, 3D concrete printing, and automated construction. The findings show that strategies such as carbonation curing, direct …

Strategies To Increase Attendance In Substance Use Disorder Group Treatment: Results From A Randomized Controlled Trial, Liliane Cambraia Windsor, Heather A Jones, Carla Ellis, Kennya Hooper, Andrea Rucker, Salma Musaad, Moses Okumu

Faculty, Staff and Students Publications

Background: Attendance in substance-use-disorder group-treatment is challenging with only 32% of patients attending at least one session (Substance Abuse and Mental Health Services Administration and Center for Behavioral Health Statistics and Quality. Treatment Episode Data Set (TEDS): 2023 admissions to and discharges from substance use treatment services reported by single state agencies, Bethesda, 2025). The present study tested a set of strategies to increase group session attendance in Community Wise, an innovative evidence-based group-intervention delivered in harm-reduction-community-based agencies and designed to reduce alcohol and substance use among people with substance-use-disorders living in predominantly Black and disinvested communities. We examined: (1) …

Critical Assessment On Challenges And Advances In Coal Pillar Strength Estimation Techniques: A Focus On Geological Discontinuities, Abhishek Kumar Singh, Sahendra Ram

Journal of Sustainable Mining

Accurate estimation of coal pillar strength is essential for ensuring safety and operational efficiency in underground mining. Current assessment methods often face limitations in addressing time-dependent failure mechanisms, geological discontinuities, and dynamic loading conditions. This paper identifies future research directions aimed at enhancing the reliability of pillar strength evaluations. One important focus is the development of advanced numerical models that account for time-dependent behaviours such as creep and fatigue. Incorporating multi-scale modelling techniques, which connect micro-scale material responses to macro-scale structural performance, may lead to more precise predictions. The integration of real-time monitoring systems measuring stress, deformation, and environmental factors …

Depressive Symptoms And Functional Disability Among Older Adults In Nakhon Ratchasima Province, Thailand: A Cross-Sectional Population-Based Study, Jiranya Bureemas, Atthawit Singsalasang

Journal of Health Research

Background: Depressive symptoms have been associated with activities of daily living (ADL) disability; however, evidence among Thai older adults remains limited and inconsistent. This study investigates the association between depressive symptoms and ADL disability in older Thai adults.

Methods: A cross-sectional analytic study was conducted among 312 older adults in Nakhon Ratchasima, Thailand, who were selected using a multistage sampling method. Data were collected between April and July 2023 using structured questionnaires covering demographic and environmental variables. Depressive symptoms were assessed using the 15-item Geriatric Depression Scale. ADL disability was measured using the Barthel and Chula ADL Indices. Multiple logistic …

Proceedings: Nownet Arts Conference 2019, Sarah Rose Weaver, Chris Chafe, Scott Oshiro, Margaret Schedel

Journal of Network Music and Arts

Proceedings of the 2nd Annual NowNet Arts Conference 2019 “Social Purpose in Contemporary Network Arts.” The conference was held November 7–10, 2019. The primary in-person site was the Institute for Advanced Computational Science (IACS), Stony Brook University. Satellite in-person sites included Center for Computer Research in Music and Acoustics at Stanford University, Edinburgh Napier University, Orpheus Institute in Belgium, and Electronic Studios at the Technical University, Berlin. More locations participated remotely via the internet.

Proceedings: Nownet Arts Conference 2018, Sarah Rose Weaver, Chris Chafe, Margaret Schedel, Min Xiao-Fen

Journal of Network Music and Arts

Proceedings of the NowNet Arts Conference 2018, “Network Music: Artistic and Technological Strategies for Public and Private Networks.” This was the first of the NowNet Arts Conferences, which have been held annually from 2018 to the present. The conference took place from April 19–22, 2018, at the Institute for Advanced Computational Science (IACS), Stony Brook University, and at multiple remote locations connected via the internet.

Comparing Text Score Strategies For Online Music Making, Craig Pedersen, Lindsay R. Vickery, Stuart James

Journal of Network Music and Arts

This paper investigates a range of approaches to using text scores in online and networked music performance, focusing on their alignment with strategies proposed by Wilson (2020) for aesthetic and technical approaches to networked music performance. Text scores, emerging from the experimental music movement of the 1960s, communicate musical ideas through words rather than traditional notation, taking instructional, allusive, and hybrid forms. Although there are many aesthetic and pragmatic approaches to text score composition, the temporal openness of many such works makes the medium well-suited to the latency-challenged practice of telematic performance. The study evaluates four text scores—Craig Pedersen’s July …

Listening Ahead Ever So Slightly, Chris Chafe, Mike Dickey

Journal of Network Music and Arts

This paper presents a novel packet loss concealment system called “Regulator,” designed for interactive network audio applications, particularly server-mediated “jam rooms” in the cloud, where large ensembles of musicians perform together synchronously. The system addresses the critical challenge of maintaining continuous high-quality audio output while minimizing latency penalties in unreliable network environments including Wi-Fi. The Regulator architecture combines four core components: a central Regulator class orchestrating packet loss concealment operations; a BurgAlgorithm class implementing maximum entropy autoregressive prediction to reconstruct missing audio samples; a Channel class providing per-channel independent modeling for multi-channel streams; and a RegulatorWorker class offering asynchronous processing …

Pulse Before Sound: Reimagining Presence And Liveness In Telematic Music Performance Through Midi-Native Collaboration, Matt C. Bray

Journal of Network Music and Arts

Telematic Music Performance heralds a new paradigm for human creativity, seeking to extend the practical limits imposed by physical co-presence and to permit the cooperative, simultaneous creation of music among geographically remote collaborators. This paper examines how MIDI-native interaction provides a structurally robust alternative to audio-centric telematic systems constrained by latency, bandwidth, and waveform fidelity. Drawing on practice-led research, including over 34 hours of documented improvisation across 91 networked sessions in the SHOALZ series—a longitudinal Telemidi performance research initiative (2022–2024)—the study examines how the Telemidi system employs MIDI as a primary substrate for remote musical collaboration by establishing a synchronized …

Euscorpius Emae Sp. N. (Scorpiones: Euscorpiidae), A New Scorpion Species From Montenegro, František Kovařík

Euscorpius

A new species Euscorpius emae sp. n. (Scorpiones: Euscorpiidae) from Montenegro is described, fully complemented with color photographs. E. emae sp. n. is morphologically unique by yellow to orange color, very narrow metasoma and enlarged chela. Pedipalp patella external trichobothria numbers are 4eb, 4eb_a, 2esb, 4em, 4est, 5et, and ventral aspect of patella with 9 trichobothria.

Mississippi Libraries Volume 88, Number 1 And 2

Mississippi Libraries

No abstract provided.