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Some Observations Of A Genealogist, 1965-1973, William D. Mccain Jul 2026

Some Observations Of A Genealogist, 1965-1973, William D. Mccain

Journal of Mississippi History

No abstract provided.


The Lumber Industry In Laurel, Mississippi, At The Turn Of The Nineteenth Century, Marvin Bentley Jul 2026

The Lumber Industry In Laurel, Mississippi, At The Turn Of The Nineteenth Century, Marvin Bentley

Journal of Mississippi History

No abstract provided.


Historic Institutional Change In The Mississippi Economy, Thomas R. Eason Jul 2026

Historic Institutional Change In The Mississippi Economy, Thomas R. Eason

Journal of Mississippi History

No abstract provided.


Incorporated Banks And The Economic Development Of Mississippi, 1829-1837, Jo Dent Hodge Jul 2026

Incorporated Banks And The Economic Development Of Mississippi, 1829-1837, Jo Dent Hodge

Journal of Mississippi History

No abstract provided.


Editor's Page, Unknown Authors Jul 2026

Editor's Page, Unknown Authors

Journal of Mississippi History

No abstract provided.


Collaborating With Our Ai Research Companion: Exploring The Use Of Microsoft Copilot To Conduct Inductive And Deductive Coding In Qualitative Research, David Wolff, Melissa Wolff, Mark Diacopoulos Jul 2026

Collaborating With Our Ai Research Companion: Exploring The Use Of Microsoft Copilot To Conduct Inductive And Deductive Coding In Qualitative Research, David Wolff, Melissa Wolff, Mark Diacopoulos

The Interactive Journal of Global Leadership and Learning

Higher Education faculty balance time in teaching, scholarship, and service, along with many other duties in their roles (Office of Occupational Statistics and Employment Projections, 2024). In our efforts to be stewards of our time and craft, faculty look for ways to be more efficient in these areas. With the increase of Artificial Intelligence (AI) in our personal and professional lives, this paper discusses the use of Generative Artificial Intelligence (GAI), Microsoft Copilot, as an analytic tool in the qualitative data analysis process. Qualitative data was collected from transcripts of recorded meetings and an online journal that included text and …


Exploring Stress And Mindfulness In Central Asia: Perspectives Of English Language Students In Uzbekistan, Laurie A. Wolfe, Rakhmatullo Akhmedov Jul 2026

Exploring Stress And Mindfulness In Central Asia: Perspectives Of English Language Students In Uzbekistan, Laurie A. Wolfe, Rakhmatullo Akhmedov

The Interactive Journal of Global Leadership and Learning

Stress is a growing concern among university students worldwide, yet little is known about how stress is conceptualized and experienced within Central Asia, particularly Uzbekistan. This study explores how Uzbek university students understand and experience stress, identifies the primary sources of stress in their daily lives, and examines their perceptions of mindfulness as a potential stress‑reduction strategy. Participants were 60 students, primarily Muslim women, at a large public university in Tashkent, Uzbekistan. Open‑ended questions on a post‑intervention survey were analyzed using a combination of deductive and inductive coding. Students most frequently described stress in emotional terms, including irritability, sadness, and …


Embedding Evaluation For Continuous Improvement In A Cohort-Based Doctoral Residency Model: Evidence From An Ed.D. Program, Monica J. Weir Jul 2026

Embedding Evaluation For Continuous Improvement In A Cohort-Based Doctoral Residency Model: Evidence From An Ed.D. Program, Monica J. Weir

The Interactive Journal of Global Leadership and Learning

The Doctor of Education (Ed.D.) in Educational Leadership Program at Minnesota State University Moorhead (MSUM) includes two required summer residency weeks that serve as signature components of the doctoral experience. Given their central role in supporting academic milestones and scholarly community, program faculty have embedded systematic evaluation into residency design to support continuous improvement. This article describes a multi-phase, utilization-focused evaluation framework examining residency preparation, implementation, and participant experience. The evaluation designer collaborated with program faculty to design pre- and post-residency week instruments that elevate doctoral student voice and support faculty-led reflection. Preliminary findings indicated strong value placed on peer …


Breaking The Mold: An Examination Of Student Perceptions With Faculty-Led Native American Student Research Experiences, Caitlin A. Johnson Jul 2026

Breaking The Mold: An Examination Of Student Perceptions With Faculty-Led Native American Student Research Experiences, Caitlin A. Johnson

The Interactive Journal of Global Leadership and Learning

In recent years, Native American students in Minnesota have experienced the state’s widest equity gap. In response, a faculty advisor guided students through an immersive Indigenous research experience using the medicine wheel as a learning model focused on culturally relevant topics. Culturally relevant teaching uses methods and techniques that are building from a student’s interests, values, and strengths helps them to have a more meaningful educational experience by connecting home with school (Gay, 2000). Grounded in culturally relevant teaching theory, this approach connects students’ lived experiences to academic learning, making the exploration of equity gaps particularly meaningful for Indigenous students …


From Framework To Praxis: An Examination Of Integrated Comprehensive Systems (Ics) Equity Reform And Black Student Engagement, Heather L. Dunham Jul 2026

From Framework To Praxis: An Examination Of Integrated Comprehensive Systems (Ics) Equity Reform And Black Student Engagement, Heather L. Dunham

The Interactive Journal of Global Leadership and Learning

For over two decades, the Integrated Comprehensive Systems (ICS) framework (Frattura & Capper, 2007) has sought to promote systemic equity by addressing the organizational structures and practices that shape student outcomes. Despite its promise, few studies have examined ICS implementation in practice, particularly its impact on Black student engagement and academic success. This qualitative case study investigates a racially diverse Midwestern middle school that adopted ICS to shift outcomes for Black students. Grounded in the ICS framework—conceptually informed by Critical Race Theory and Disability Studies in Education—data from interviews, observations, and achievement records reveal that ICS can disrupt racialized routines, …


Re-Reading The World: Why Critical Literacy Must Accompany The “Back To Basics” Movement, Carl Bryan Jul 2026

Re-Reading The World: Why Critical Literacy Must Accompany The “Back To Basics” Movement, Carl Bryan

The Interactive Journal of Global Leadership and Learning

Recent literacy reforms in the United States have prioritized systematic phonics as part of the “science of reading,” backed by extensive evidence on the importance of phonemic awareness and decoding for early reading development. While these skills are essential, narrowing literacy to mechanics alone overlooks its broader cultural and civic purposes. Drawing on Freire’s (1970/2000) conception of literacy as both “reading the word and the world,” this paper argues for a balanced framework that integrates foundational instruction with comprehension, knowledge building, and critical literacy. Building on the work of Luke (2000) and Vasquez (2014), it positions literacy as both a …


Emotional Sobriety As Liberation: A Critical Pedagogy Of Resilience, Carl Bryan Jul 2026

Emotional Sobriety As Liberation: A Critical Pedagogy Of Resilience, Carl Bryan

The Interactive Journal of Global Leadership and Learning

This white paper extends the Reclaiming Model of trauma recovery by examining what follows critical consciousness when trauma persists and systems remain largely unchanged. Building on Reclaiming My Story, which framed healing as a Freirean act of reclaiming authorship through naming harm, dialogue, and praxis (Bryan, 2026), this paper addresses how reclaimed consciousness is sustained under ongoing emotional, relational, and structural strain. Drawing on critical pedagogy, trauma scholarship, and a first-person case narrative, it reframes post-trauma survival not as incomplete recovery but as ongoing praxis. The analysis challenges resolution-based and individualizing models of healing by conceptualizing emotional sobriety, relational regulation, …


Provocable Forgiveness In Noisy Brand--Consumer Systems:An Agent-Based Study Of Repeated Interaction, Tahere Ahmadiyan, Hamidreza Navidi, Behbod Keshavarzi Jul 2026

Provocable Forgiveness In Noisy Brand--Consumer Systems:An Agent-Based Study Of Repeated Interaction, Tahere Ahmadiyan, Hamidreza Navidi, Behbod Keshavarzi

Northeast Journal of Complex Systems (NEJCS)

Repeated brand--consumer exchange is often treated as a managerial problem of loyalty, recovery, and trust. It can also be read as a small complex system: many local decisions about cooperation, retaliation, and forgiveness accumulate into market-level selection. This study uses that perspective to examine which relational rules survive when communication is imperfect. Eight canonical Iterated Prisoner's Dilemma strategies are translated into marketing archetypes and evaluated through round-robin tournaments, a six-level noise sweep, proportional-fitness ecological dynamics, and finite-population Moran invasion tests. The tournament leaderboard is calculated without same-strategy self-play, so that reported payoffs reflect inter-archetype competition rather than homogeneous self-coordination. At …


Adult-Onset Iga Vasculitis Initially Attributed To A Cutaneous Drug Reaction And Diverticulitis, Leila C. Tou, Catherine Grace P. Hobayan, Shane Devine, Sarah Koraym Jul 2026

Adult-Onset Iga Vasculitis Initially Attributed To A Cutaneous Drug Reaction And Diverticulitis, Leila C. Tou, Catherine Grace P. Hobayan, Shane Devine, Sarah Koraym

Journal of Community Hospital Internal Medicine Perspectives

Immunoglobulin A vasculitis (IgAV), formerly Henoch–Schönlein purpura, is a small-vessel vasculitis characterized by palpable purpura, arthralgias, gastrointestinal involvement, and renal disease. Although IgAV is common in children, adult-onset disease is rare and may be associated with more severe manifestations, particularly renal involvement. In adults, IgAV may be difficult to recognize because of overlap with more common gastrointestinal, infectious, or medication-related conditions. We present a case of adult-onset IgAV initially attributed to presumed diverticulitis and later to a drug eruption following antibiotic exposure. This case highlights diagnostic pitfalls and the importance of early recognition and renal surveillance.


Rare Presentation Of Sequential Mucosa-Associated Lymphoid Tissue Lymphoma, Follicular Lymphoma, And Chronic Lymphocytic Leukemia: A Case-Based Review, Khushi J. Desai, Ansy H. Patel, Patrick T. O’Dowd, Joseph A. Tworek, Preeti G. Misra, Li Ding Jul 2026

Rare Presentation Of Sequential Mucosa-Associated Lymphoid Tissue Lymphoma, Follicular Lymphoma, And Chronic Lymphocytic Leukemia: A Case-Based Review, Khushi J. Desai, Ansy H. Patel, Patrick T. O’Dowd, Joseph A. Tworek, Preeti G. Misra, Li Ding

Journal of Community Hospital Internal Medicine Perspectives

Introduction: Occurrence of 2 (or more) Hodgkin's and non-Hodgkin's lymphoma concordantly or sequentially in a single patient is very rare.

Case: An 88-year-old Italian male with a history of mucosa-associated lymphoid tissue (MALT) lymphoma in remission and indolent follicular lymphoma under surveillance, presented with acute autoimmune hemolytic anemia (AIHA). While initially speculated to be secondary to follicular lymphoma relapse, stable mesenteric lymphadenopathy compared to prior CT abdomen/pelvis and smudge cells on peripheral smear prompted further evaluation. Peripheral blood flow cytometry indicated a mature B-cell neoplasm, which was confirmed to be chronic lymphocytic leukemia (CLL) with a bone marrow biopsy. Minimal …


Progressive Facial Swelling And Airway Symptoms Revealing A Deep Neck Abscess With Atypical Microbiology, Drew Knight, Hakam Sulaiman, Arash Bakian, Ilya Fonarov Jul 2026

Progressive Facial Swelling And Airway Symptoms Revealing A Deep Neck Abscess With Atypical Microbiology, Drew Knight, Hakam Sulaiman, Arash Bakian, Ilya Fonarov

Journal of Community Hospital Internal Medicine Perspectives

Deep neck abscesses have become less common in the antibiotic era; yet, they still pose major risks of morbidity and mortality if not addressed appropriately. Their proximity to the upper respiratory tract and mediastinal structures further exacerbates this risk. We present the case of a 56-year-old man with a medical history of type 2 diabetes mellitus, who exhibited a two-month history of recurrent left-sided facial edema, pain, and dysphagia. Computed tomography imaging confirmed a substantial fluid collection extending from the submandibular region into the mid-cervical area, from which aspiration yielded 110 mL of purulent material. Cultures indicated Cutibacterium acnes, …


Duodenal Perforation From Dislodged Prophylactic Pancreatic Stent Following Ercp For Hilar Cholangiocarcinoma: A Rare Adverse Event, Mina Alkomos, Jolie Ibrahim, Karan Desai, Beshoy Effat Elkomos, Walid Baddoura, Youssef Botros Jul 2026

Duodenal Perforation From Dislodged Prophylactic Pancreatic Stent Following Ercp For Hilar Cholangiocarcinoma: A Rare Adverse Event, Mina Alkomos, Jolie Ibrahim, Karan Desai, Beshoy Effat Elkomos, Walid Baddoura, Youssef Botros

Journal of Community Hospital Internal Medicine Perspectives

We report a rare complication of prophylactic pancreatic duct stenting during ERCP for suspected hilar cholangiocarcinoma. A 47-year-old woman presented with two weeks of painless jaundice, total bilirubin 18 mg/dL, and cholestatic enzymes. Imaging revealed intrahepatic biliary dilation without CBD dilation. ERCP with cholangioscopy identified a right hepatic duct stricture; biopsies were obtained. A 10 mm × 4 cm covered metal stent was placed in the CBD, a 7 Fr × 12 cm plastic stent in the right hepatic duct, and a 4 Fr × 5 cm pancreatic stent was prophylactically inserted after inadvertent duct cannulation. Two days later, she …


A Case Of Nivolumab-Induced Bullous Pemphigoid- Successfully Treated With Rituximab, Rawa Amin, Neel Ranpura, Haris Hatic Jul 2026

A Case Of Nivolumab-Induced Bullous Pemphigoid- Successfully Treated With Rituximab, Rawa Amin, Neel Ranpura, Haris Hatic

Journal of Community Hospital Internal Medicine Perspectives

Drug-associated bullous pemphigoid (DABP) refers to cases of bullous pemphigoid caused by exposure to various drugs. We present a case of nivolumab (a programmed cell death-ligand 1 (PD-L1) inhibitor) induced bullous pemphigoid in a patient treated for classic Hodgkin’s lymphoma, presenting four months after cessation of therapy. The patient demonstrated minimal clinical response to steroids and methotrexate. Following initiation of rituximab, the patient experienced rapid improvement of the rash with no further disease progression


Corynebacterium Bacteremia In A High-Risk Host: A Diagnostic Dilemma Of Contamination Versus True Infective Endocarditis, Arman Manjikian, Christopher Aboujaoude, Nicole Rock, Don Pepito Jul 2026

Corynebacterium Bacteremia In A High-Risk Host: A Diagnostic Dilemma Of Contamination Versus True Infective Endocarditis, Arman Manjikian, Christopher Aboujaoude, Nicole Rock, Don Pepito

Journal of Community Hospital Internal Medicine Perspectives

Corynebacterium species are often regarded as skin contaminants when isolated from clinical cultures. However, in select high-risk patients, these organisms can lead to significant infections, including infective endocarditis. We present the case of a 76-year-old woman with multiple comorbidities, including end stage renal disease (ESRD) on hemodialysis and an exposed tunneled central catheter, who developed Corynebacterium-associated native mitral valve endocarditis requiring surgical intervention. Despite prompt antimicrobial therapy and bioprosthetic valve replacement, her hospital course was complicated by heart block, empyema, and eventual cardiac arrest. This case highlights the importance of recognizing Corynebacterium as a potential pathogen in vulnerable patients …


Left-Ventricular Non-Compaction Cardiomyopathy Presenting With Atrial Flutter With Rapid Ventricular Response, Sahil Ghay, Baneet Kaur, J. Armando Talavera, Koushik Sanku, Viky S. Loescher, Julien A. Exposito Jul 2026

Left-Ventricular Non-Compaction Cardiomyopathy Presenting With Atrial Flutter With Rapid Ventricular Response, Sahil Ghay, Baneet Kaur, J. Armando Talavera, Koushik Sanku, Viky S. Loescher, Julien A. Exposito

Journal of Community Hospital Internal Medicine Perspectives

Left ventricular non-compaction cardiomyopathy (LVNC) is a rare genetic cardiomyopathy characterized by prominent trabeculations and deep recesses that predispose to arrhythmias and heart failure. We describe a 42-year-old man with persistent tachycardia and exertional fatigue found to have CTI-dependent atrial flutter with 2:1 conduction. Transesophageal echocardiography showed severe biventricular dysfunction with an ejection fraction of 15%, and cardiac MRI confirmed LVNC with a non-compacted to compacted ratio of 3.3. After successful ablation and normal coronary angiography, he was diagnosed with LVNC. This case highlights an unusual presentation of LVNC with typical atrial flutter and underscores the value of cardiac MRI …


Rasmussen’S Aneurysm: A Rare But Life-Threatening Complication Of Pulmonary Tuberculosis – A Case Report., Karan Puri Jul 2026

Rasmussen’S Aneurysm: A Rare But Life-Threatening Complication Of Pulmonary Tuberculosis – A Case Report., Karan Puri

Journal of Community Hospital Internal Medicine Perspectives

Rasmussen’s aneurysm is a rare but potentially fatal complication of pulmonary tuberculosis. It represents a pseudoaneurysm of a pulmonary arterial branch caused by erosion of the arterial wall secondary to chronic inflammation within a tuberculosis cavity. Although uncommon, especially in non-endemic regions, rupture of this aneurysm can result in massive hemoptysis and carries a high mortality if not promptly recognized and managed. We report a case of a healthcare worker in the United States, a non-endemic region, who presented with massive, life-threatening hemoptysis. She was found to have active pulmonary tuberculosis. Computed tomography angiography demonstrated a 10-mm pseudoaneurysm arising from …


Rectal Dieulafoy Lesion With Severe Hematochezia In A Warfarin-Treated Patient, Carlos Elizondo Alatorre, Maria Gabriela Rubianes Guerrero, Julio C Valencia Manrique, Jennifer Harley Jul 2026

Rectal Dieulafoy Lesion With Severe Hematochezia In A Warfarin-Treated Patient, Carlos Elizondo Alatorre, Maria Gabriela Rubianes Guerrero, Julio C Valencia Manrique, Jennifer Harley

Journal of Community Hospital Internal Medicine Perspectives

Dieulafoy lesions (DLs) are rare vascular malformations in the gastrointestinal tract that often present with gastrointestinal bleeding, most commonly in the stomach. Rectal DLs are exceptionally rare, representing less than 2% of cases. Warfarin use increases the risk for bleeding and management represents a challenge. We present a case of a 60-year-old male on chronic warfarin therapy who presented with severe hematochezia due to a rectal DL, requiring more than one colonoscopy and prothrombin complex concentrate (PCC) administration. While guidelines recommend PCC over fresh frozen plasma (FFP), they acknowledge that this is based on very low certainty of evidence.


A Case Of Anti-Srp Immune-Mediated Necrotizing Myopathy Following Suspected Coxsackie B4 Infection: Exploring A Viral Trigger Hypothesis, Marwan Ahmed, Ruba Salameh, Soziema Salia, Brent T. Harris, Christopher J. Haas, Anees Siddiqi Jul 2026

A Case Of Anti-Srp Immune-Mediated Necrotizing Myopathy Following Suspected Coxsackie B4 Infection: Exploring A Viral Trigger Hypothesis, Marwan Ahmed, Ruba Salameh, Soziema Salia, Brent T. Harris, Christopher J. Haas, Anees Siddiqi

Journal of Community Hospital Internal Medicine Perspectives

Immune-mediated necrotizing myopathy (IMNM) is a rare subtype of idiopathic inflammatory myopathies that can present with rhabdomyolysis. We report a 43-year-old woman with rapidly progressive proximal muscle weakness following a flu-like illness. Laboratory evaluation revealed markedly elevated creatine kinase (22,207 U/L) and transaminases, with positive anti-signal recognition particle (SRP) and Coxsackie B4 antibodies. Muscle biopsy demonstrated extensive necrosis, regeneration, and endomysial lymphocytic infiltration, confirming IMNM. The patient was treated with intravenous methylprednisolone, IVIG, and rituximab, followed by oral steroid taper and mycophenolate. At six-month follow-up, she showed significant clinical and biochemical improvement. This case highlights a potential viral-triggered autoimmune mechanism, …


Primary Cardiac And Renal Amyloidosis With Nephrotic Syndrome In A Patient With A Remote History Of Partial Nephrectomy For Renal Cell Carcinoma, Gaurav Bector, Prateek Jain, Mahyar Toofantabrizi, Christopher J Haas Jul 2026

Primary Cardiac And Renal Amyloidosis With Nephrotic Syndrome In A Patient With A Remote History Of Partial Nephrectomy For Renal Cell Carcinoma, Gaurav Bector, Prateek Jain, Mahyar Toofantabrizi, Christopher J Haas

Journal of Community Hospital Internal Medicine Perspectives

Background: Primary AL amyloidosis is a rare systemic disorder caused by deposition of misfolded immunoglobulin light chains, leading to multi-organ dysfunction. Renal cell carcinoma (RCC) is common, with an age-adjusted incidence of 16.4 per 100,000 persons per year in the US (2017–2021). Post-partial nephrectomy, mild proteinuria may occur, but progressive glomerular disease such as AL amyloidosis years later is rare.

Case Presentation: A 73-year-old man with ulcerative colitis, type 2 diabetes, RCC post right partial nephrectomy (10 years prior), and prostate cancer post-prostatectomy (4 years prior) presented with fatigue and bilateral leg edema. Laboratory evaluation revealed acute kidney injury with …


Steroid-Responsive Encephalopathy Associated With Autoimmune Thyroiditis: A Case Fulfilling Definite Graus Criteria, Stephanie Ammari, Nawras Ibrahim, Sravani Karuchola, Samir Ouais Jul 2026

Steroid-Responsive Encephalopathy Associated With Autoimmune Thyroiditis: A Case Fulfilling Definite Graus Criteria, Stephanie Ammari, Nawras Ibrahim, Sravani Karuchola, Samir Ouais

Journal of Community Hospital Internal Medicine Perspectives

Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), also known as Hashimoto encephalopathy, is a rare immune-mediated neurological syndrome with an incidence of 2.1 per 100,000 and a 4:1 female predominance. Neurological manifestations are independent of thyroid status, occurring in 30–40% of euthyroid patients, and include cognitive impairment, confusion, seizures, and psychiatric symptoms. Diagnosis is challenging in the elderly, where symptoms overlap with dementia or delirium, with only 51 reported cases in patients aged ≥65 years. We describe a 70-year-old woman with autoimmune hypothyroidism and levothyroxine nonadherence who presented with progressive weakness, melena, dyspnea, and altered mental status complicated by obstructive …


Piperacillin-Induced Immune Hemolytic Anemia Masked By Intestinal Failure-Associated Liver Disease: A Case Report With Three Serial Exposures, Stephanie Ammari, Nawras Ibrahim, Khalid Mahmood Jul 2026

Piperacillin-Induced Immune Hemolytic Anemia Masked By Intestinal Failure-Associated Liver Disease: A Case Report With Three Serial Exposures, Stephanie Ammari, Nawras Ibrahim, Khalid Mahmood

Journal of Community Hospital Internal Medicine Perspectives

Background: Drug-induced immune hemolytic anemia (DIIHA) secondary to piperacillin has an estimated incidence of 0.01–0.10% [1,2]. In patients with intestinal failure-associated liver disease (IFALD), chronic conjugated hyperbilirubinemia obscures typical hemolytic markers [3,4].

Case Presentation: A 27-year-old woman with traumatic short bowel syndrome requiring total parenteral nutrition for 6 months, IFALD (baseline total bilirubin 2.5 mg/dL), and chronic kidney disease experienced three piperacillin-tazobactam exposures over two months. First exposure (12 days): hemolysis developed after drug discontinuation (primary sensitization). Second exposure: severe hemolysis occurred within 3 days (anamnestic response) with hemoglobin declining to 5.8 g/dL, undetectable haptoglobin, elevated LDH, reticulocytosis, and strongly …


Extranodal Marginal Zone Lymphoma Of The Breast In A Patient With Chronic Hepatitis C Infection: A Case Report, Ravneet K Dhanoa, Bipasha Goyal, Prateek Jain, Marilyn Baird-Howell, Mounika Gangireddy Jul 2026

Extranodal Marginal Zone Lymphoma Of The Breast In A Patient With Chronic Hepatitis C Infection: A Case Report, Ravneet K Dhanoa, Bipasha Goyal, Prateek Jain, Marilyn Baird-Howell, Mounika Gangireddy

Journal of Community Hospital Internal Medicine Perspectives

Primary breast lymphomas account for less than 1% of all non-Hodgkin lymphomas and 0.04–0.5% of all malignant breast neoplasms. We report a case of breast extranodal marginal zone lymphoma (EMZL) in a 60-year-old woman with chronic hepatitis C virus (HCV) infection. After comprehensive evaluation excluded other known etiologies, chronic HCV infection emerged as the most plausible contributing factor. Epidemiologic and biological evidence supports an association between HCV and B-cell non-Hodgkin lymphomas, particularly marginal zone lymphomas. Our case adds to the limited literature suggesting that HCV should be considered as a potential etiological factor in breast EMZL. We discuss the emerging …


A Tight Squeeze – Cardiac Tamponade In A Scleroderma Patient, Ifrah Nadeem, Charles E Geringer Jul 2026

A Tight Squeeze – Cardiac Tamponade In A Scleroderma Patient, Ifrah Nadeem, Charles E Geringer

Journal of Community Hospital Internal Medicine Perspectives

Systemic Sclerosis (SSc) is an autoimmune connective tissue disease marked by multiorgan fibrosis, including cutaneous involvement, and vasculopathy. Primary heart involvement in systemic sclerosis (SSc-pHI) includes heart failure, arrhythmia, pericarditis, pericardial effusion, valve disorders, and myocarditis. SSc-pHI remains a leading cause of mortality in this population. Pericardial effusion in SSc is usually associated with heart failure, pulmonary hypertension, and end-stage kidney disease. Cardiac tamponade is a rare initial presentation of SSc-pHI but carries a worse prognosis. Diagnosis is often challenging due to subclinical manifestations and requires advanced imaging modalities such as transthoracic echocardiography with tissue doppler and cardiac magnetic resonance …


A Case Of N-Methyl-D-Aspartate (Nmda) Autoimmune Encephalitis In A 34-Year-Old Man Thought To Have Schizophrenia, Riyad Amin, Michael Wilson, Morgan Koontz, Khawaja Omar Jul 2026

A Case Of N-Methyl-D-Aspartate (Nmda) Autoimmune Encephalitis In A 34-Year-Old Man Thought To Have Schizophrenia, Riyad Amin, Michael Wilson, Morgan Koontz, Khawaja Omar

Journal of Community Hospital Internal Medicine Perspectives

Background: N-methyl-D-aspartate (NMDA) autoantibody encephalitis is a rare autoimmune condition affecting approximately 1.5 per million people per year [1]. It predominantly occurs in young women and is often associated with tumors, particularly teratomas [3]. The diagnosis is aided by testing cerebrospinal fluid (CSF) or serum for NMDA receptor antibodies along with careful evaluation of symptoms. Misdiagnosis is common, as its symptoms can mimic other more prevalent conditions, such as upper respiratory illnesses or psychiatric disorders like acute psychosis or schizophrenia.

Case Report: We present the case of a 34-year-old man who was initially incarcerated and subsequently developed decreased communication and …


Severe Multisystem Toxicity From Combination Ipilimumab And Nivolumab In Metastatic Melanoma: A Case Report, Bushra Amer, Sheetal Manerkar Jul 2026

Severe Multisystem Toxicity From Combination Ipilimumab And Nivolumab In Metastatic Melanoma: A Case Report, Bushra Amer, Sheetal Manerkar

Journal of Community Hospital Internal Medicine Perspectives

Immune checkpoint inhibitors (ICIs) have transformed cancer therapy by enhancing antitumor immunity. Despite their remarkable efficacy in malignancies, particularly metastatic melanomas, the use of ICIs have been linked to life-threatening immune-related adverse events (irAEs) affecting several organ systems. Combination therapy with ipilimumab and nivolumab increases both efficacy and the risk of severe irAEs. We report a rare case of metastatic melanoma treated with combination ipilimumab and nivolumab, complicated by multisystem irAEs. The patient developed hepatitis, cholangitis, ocular toxicity, and neurologic progression, highlighting the severity and complexity of immune-mediated toxicities following dual checkpoint blockade. This case underscores the potential for severe, …