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Virginia Journal Of Public Health Spring 2024

Virginia Journal of Public Health

No abstract provided.

Factors Affecting Adherence To Antiretroviral Therapy Among People Living With Hiv/Aids In Antigua And Barbuda, Yuliecia Antoinette Rowe-Harris Mrs, Chirlynor Ebora Calbayan Mrs, Kepha Odiwuor Pondi Mr

Adventist Human-Subject Researchers Association

This study examined factors affecting adherence to antiretroviral therapy (ART) among people living with HIV/AIDS in Antigua and Barbuda. The findings identified multiple variables, emphasizing the dynamic components affecting ART adherence. These findings address a local gap and provide insights into the unique adherence challenges faced by a vulnerable population.

Medical School Watercooler Newsletter - May 23, 2024, Lindsey Lyle

Watercooler Newsletter

This is the May 23, 2024 edition of the Frederick P. Whiddon College of Medicine’s newsletter - Watercooler.

Contents Include

• Tuckey earns Outstanding Young Scientist Award at research symposium
• Graduate student earns national scholarship for research
• Basic medical sciences student wins Stanford BioX Award
• M3 Case Symposium set for June 7
• Pediatric patients may rate pain differently than caregivers, study finds

Lateral Flow Devices: Applying Antigen-Antibody Interaction For Vaccine Technology, Mirna González-González, Marco Rito-Palomares

Vaccine Technology IX

Please click Additional Files below to see the full abstract.

Recombinant Interleukins As Vaccine Adjuvants Against Livestock Diseases, Berenice Calderón-Pérez, Leandro Alberto Nuñez-Muñoz, Ana María Cortés-López, Pedro Ricardo Rodríguez-Farrera, Roberto Ruiz-Medrano, Beatriz Xoconostle-Cázares, Areli Margarita Martínez-Morales

Vaccine Technology IX

Please click Additional Files below to see the full abstract.

Acheviements Of A Vaccine Development Unit Within Lmics; Biotechnology Development Unit, Institut Pasteur De Tunis, Tunisia, Samia Rourou, Amani Chaabene, Said Salhi, Samy Majoul, Khaled Trabelsi, Hana Askri, Hela Kallel

Vaccine Technology IX

Please click Additional Files below to see the full abstract.

Advances In Alternative Routes Of Vaccine Administration, And Continued Challenges, Tanima Sinha

Vaccine Technology IX

Please click Additional Files below to see the full abstract.

Efficacy Of Ferula L. Species Extracts From Tajikistan Against Influenza Viruses, Saidbeg Satorov, Sulhiy Mavlonazarova, Ahdrey P. Bogoyavlenskiy, Salomuddin D. Yusufi, Vyacheslav Dushenkov

Publications and Research

Efficacy of Ferula L. Species Extracts from Tajikistan Against Influenza Viruses One of the challenges facing both the domestic and international pharmaceutical industries is the limited selection and suboptimal efficacy of available antiviral drugs. The high mutational variability of influenza viruses contributes to rapid acquisition of drug resistance, which diminishes or nullifies the effectiveness of existing therapies, thereby necessitating the exploration for novel therapeutics. This study aimed to assess the antiviral activities of three species of the genus Ferula— indigenous to the Republic of Tajikistan—against influenza strains A/Vladivostok/2/09 (H1N1) and A/Almaty/8/98 (H3N2). The investigation revealed that phytochemical constituents—specifically, root …

Break Through The Mold: Hyper-Ige Syndrome As A Vehicle For Invasive Aspergillosis, Stephen Smetana Do, Joseph Nordin Do, Rachel Johnson Md, Angela Gableman Md, Nicholas Nassif Md, Ms

Scientific Day

No abstract provided.

Mycobacterium Avium Complex Vertebral Osteomyelitis And Retroperitoneal Abscess In An Immunocompetent Patient: A Case Report, Jacob Nelson Md, Kazi Khan Md, William Macdonald Md

Scientific Day

No abstract provided.

Peripheral Mononeuropathy In A Pediatric Patient Following Episode Of Severe Diabetic Ketoacidosis: A Case Report, Kelly Fahey Dpm, Andrew Silman Dpm, Eyad Xoubi Dpm, Patrick Sanchez Dpm

Scientific Day

No abstract provided.

May 22, 2024 Greenmail, University Of Alabama At Birmingham

GreenMail (student newsletter through 2024)

No abstract provided.

Podiatrists' Experiences With Telemedicine During Covid-19, Jeavon Inniss

Walden Dissertations and Doctoral Studies

Telemedicine was one of the most beneficial technologies to improve patient access to care during the COVID-19 pandemic. Telemedicine has been well-researched in the hospital and primary care setting. There is a paucity of research that has focused on the experiences of specialty providers such as podiatrists. The purpose of this qualitative study was to understand podiatrists’ perspectives on the value of telemedicine as a method of delivering care. The unified theory of acceptance and use of technology was used as a theoretical framework to aid in identifying which factors are necessary for acceptance and continued use of telemedicine in …

Sink Your Teeth Into A Curious Case Of Non-Infectious Mandibular Osteomyelitis, Kathryn Brady Do, Kelci Butler Do, Michael Tekippe Md, Phd

Scientific Day

No abstract provided.

Sjogren’S Induced Splenic Atrophy Leading To Overwhelming S. Pneumoniae Bacteremia And Purpura Fulminans, Daniel Jabr Do, Navedeep Kaur Do, Hector Roman-Perez Md, Daniel Strama Do, Daniel Grahf Md

Scientific Day

No abstract provided.

Covid-19 Tort Reform, Clayton J. Masterman

Journal Articles

In 2020 and 2021, 44 states and Washington, D.C. passed laws that limited tort liability related to COVID-19. The most common reforms immunized health care providers from malpractice or similar liability. A second category is limited liability to individuals or businesses for exposing others to the novel coronavirus. And a third category protected manufacturers of supplies used to detect and prevent COVID- 19 from products liability suits. The goals of these reforms included protecting health care providers from uncertainty in providing care for a novel disease, limiting the macroeconomic consequences of the pandemic, and encouraging the distribution of critical supplies …

A Local Rebound In Adult Invasive Group A Streptococcus (Igas) After Recent Pediatric Igas Outbreak, Nikolina Madjer Md, Daniel Rowan Do, Leon Eydelman Md, Valerie Em Griffeth Md, Phd

Scientific Day

No abstract provided.

Effectively Managing Communication After A Crisis: A Phenomenographic Study On Public Health Crises In The Country Of Jamaica, Jehan Donnique Wilson

Walden Dissertations and Doctoral Studies

Effectively managing communication after a crisis is the starting point of successful public policy and administration when handling a public health crisis. Jamaica has dealt with several public health crises over the span of its existence; this study compared SARS-CoV-2 (COVID-19) and influenza, two major Jamaican public health crises during the period from 2019 to 2022. This study’s research questions addressed (a) what specific communication strategies were used by Jamaica during the influenza outbreak as compared to the COVID-19 pandemic and (b) how the specific communications strategies used during the influenza outbreak and COVID-19 pandemic contributed to the development of …

Exploring The Lived Experience Of Counseling Leaders And Professionals In The East African Community Transitioning Through The Covid-19 Pandemic: A Phenomenological Study, Daniel Muthini Kimony

Doctoral Dissertations and Projects

The East African Community (EAC) is a regional intergovernmental assembly, currently comprising seven member states including Burundi, the Democratic Republic of Congo (DRC), Kenya, Rwanda, South Sudan, Tanzania, and Uganda. This transcendental phenomenological study examined the lived experiences of counseling leaders and professionals in the EAC as they transitioned through the COVID-19 global pandemic. Grounded in Schlossberg’s transition theory, the study explored participants’ experiences as they moved into, moved through, and moved out of the pandemic in the period between January 2020 and May 2023. Triangulated, qualitative data, assessed through transcendental and heuristic methodology, was collected from 10 participants representing …

The Stratified Leadership Model Of The First-Century Christian Church, Barton Schuyler Garratt Edsall Iv

Doctoral Dissertations and Projects

As Christianity enters its third millennium, it faces the sharpest decline in the number of people attending church congregations compared to the total population. In Romans 1:13, the Apostle Paul states that God’s people should not be ignorant that the purpose for leaders within the collective church body, beginning with himself as the example, is so the people’s lives would be fruitful–spiritually enriched and productive. Logic dictates that if the lives of those who attended Christian churches in the twenty-first century experienced and displayed such spiritual quality, attendance would not be declining but contrarily on the rise. Regarding church clergy …

Changing The Narrative: Developing Evidence-Based, Communication Strategies To Address Health Disparities Of Black Women In The United States, Emmerline Francesca Nelson-Rogers

Doctoral Dissertations and Projects

Black women experience health issues at disparate rates when compared to their racial counterparts. Although these health disparities can be linked to health behaviors, they are deeply rooted in historic, racial systems that govern our lives today. More often than not, changes in health behaviors are at the forefront of addressing these health disparities rather than historical health trends of Black women in the U.S. This study aims to discuss why the change needed is a change in the narrative for why these health disparities exist and persist as well as a change in narrative about the role Black women …

Effects Of Covid-19 On Mental Health Workers' Job Satisfaction, Employee Burnout, And Intent To Leave, Colton Jacobs

Doctoral Dissertations and Projects

The COVID-19 disease emerged in December 2019 and created a worldwide pandemic. As the COVID-19 virus spread, healthcare workers faced increased workloads and burnout due to increased stress. With a current abundance of research to better understand how the pandemic affected healthcare workers, minimal research has been conducted to investigate the effects on mental health workers. It is imperative to better understand how the consequences of the pandemic affected mental health workers due to their importance in supporting the mental well-being of our communities. This study focused on how the COVID-19 pandemic influenced job satisfaction, burnout syndrome, and intent to …

A Fur Family Protein Bosr Is A Novel Rna-Binding Protein That Controls Rpos Rna Stability In The Lyme Disease Pathogen, Sajith Raghunandanan, Raj Priya, Fuad Alanazi, Meghan C. Lybecker, Paula Schlax, X. Frank Yang

All Faculty Scholarship

The σ54-σS sigma factor cascade plays a central role in regulating differential gene expression during the enzootic cycle of Borreliella burgdorferi, the Lyme disease pathogen. In this pathway, the primary transcription of rpoS (which encodes σS) is under the control of σ54 which is activated by a bacterial enhancer-binding protein (EBP), Rrp2. The σ54-dependent activation in B. burgdorferi has long been thought to be unique, requiring an additional factor, BosR, a homologue of classical Fur/PerR repressor/activator. However, how BosR is involved in this σ54-dependent activation remains unclear and perplexing. In this study, we demonstrate that BosR does not function as …

Preparing Three Southern Baptist Churches In Mason, Tennessee, As Lighthouses Of Hope In Crisis And Disaster: The Intersection Of The Firehouse And The Church House During A Global Pandemic, Brian J. Styer

Doctoral Dissertations and Projects

The Southern Baptist Disaster Relief (SBDR) ministry program faces challenges due to limited awareness among Southern Baptist pastors, leading to inadequate promotion and participation. The proposed solution involves providing targeted education, improved advertising, and encouraging local leaders to promote engagement. The project aims to prepare three churches in Mason and Stanton, TN, to serve as Disaster Relief teams through specialized training and courses like ‘Introduction to Disaster Relief.’ The goal is to increase awareness of SBDR, recruit and train new members, and inspire individuals to become endorsed SBDR and Public Safety Chaplains. The project incorporates a theological foundation to integrate …

Twist1 Drives Cytotoxic Cd8+ T-Cell Exhaustion Through Transcriptional Activation Of Cd274 (Pd-L1) Expression In Breast Cancer Cells, Xiaobin Yu, Jianming Xu

Faculty, Staff and Students Publications

In breast cancer, epithelial-mesenchymal transition (EMT) is positively associated with programmed death ligand 1 (PD-L1) expression and immune escape, and TWIST1 silences ERα expression and induces EMT and cancer metastasis. However, how TWIST1 regulates PD-L1 and immune evasion is unknown. This study analyzed TWIST1 and PD-L1 expression in breast cancers, investigated the mechanism for TWIST1 to regulate PD-L1 transcription, and assessed the effects of TWIST1 and PD-L1 in cancer cells on cytotoxic CD8+ T cells. Interestingly, TWIST1 expression is correlated with high-level PD-L1 expression in ERα-negative breast cancer cells. The overexpression and knockdown of TWIST1 robustly upregulate and downregulate PD-L1 …

Assessing Health Needs In A Dominican Republic Community During An Interprofessional Service-Learning Trip, Gabriela Andonie, Hanna Rotundo, Ashanti Jones, Logan Dugas, Shylon Francis

Journal of Interprofessional Practice and Collaboration

Purpose: International medical missions may increase access to medicines and care, but international teams must understand local needs to implement appropriate services. In 2023, a multidisciplinary team from our institution partnered with a nonprofit organization in the barrio of Cienfuegos, Dominican Republic with the goal of strengthening local health services. The primary objective of this study was to identify health-related needs in Cienfuegos from the perspective of community members and local health care workers.

Methods: A qualitative study was conducted as part of a service-learning initiative. After obtaining informed consent, the investigators conducted individual semi-structured interviews facilitated by multi-lingual interpreters. …

The Covid-19 Vaccine Challenge Innovation Sprint: The Utility Of Active Learning In Fostering Interdisciplinary Collaboration In The Hypothetical Development Of A Covid-19 Vaccination Campaign, Jennifer Shaffer Foster, Gabriel N. Attallah, Ritika Bhajiawala, Steven J. Gabriel, Ray Huang, Parveen Attai, Maisha Rahman, Maia Weiss, Sadia M. Rifah, Oluwademilade Daniel Aguda, Dean S. Seneca, Lina Mu

The SUNY Journal of the Scholarship of Engagement: JoSE

In this paper, we discuss the design, goals, and outcome of the COVID-19 Vaccine Challenge Innovation Sprint, which provided an extracurricular, active learning opportunity for undergraduate and graduate students in Fall 2020. The design of the competition drew elements from both innovation sprints, commonly employed in technology and entrepreneurship, and global health case competitions which are largely used in academic settings. Interdisciplinary, multi-level teams of students were tasked with advancing an equitable (and at the time, hypothetical) COVID-19 immunization program with the goal of reaching as many people as possible in the region surrounding the university. We provide student participants’ …

Comparison Of The Activities And Cryoprotective Mechanism Of Two Antifreeze Peptides Derived From Silver Carp Parvalbumin, Li Jun, Fu Yuting, Yu Jian, Li Xianghong, Liu Yongle, Wang Faxiang

Food and Machinery

Objective: Explore the cryoprotective mechanism and structure-activity relationship of antifreeze peptides derived from silver carp parvalbumin. Methods: Using differential scanning calorimetry and molecular dynamics simulation to compare activity, structure and mode of action of two typical peptides. Results: Pv-AFP 1 （KAADSFNH KAFFAKVG） had a stable α-helix structure, while Pv-AFP 2 （KAADSFNHKAF） tended to exhibit random coil. The thermal hysteresis activity of Pv-AFP 1 was 0.87 ℃, which was higher than Pv-AFP 2 （0.74 ℃）. Molecular dynamics simulations showed that Pv-AFP 1 could interact with 53 water molecules, and could form 16 hydrogen bonds to adsorb onto the surface of …

Rapid Identification Of Drug Resistance Of Escherichia Coli Based On Electrochemical Square Wave Voltammetry Of Resazurin, Qi Chuchu, Lu Lisheng, Ren Jiali, Zhou Kai, Zhang Xinfang, Zhang Ziying

Food and Machinery

Objective: To evaluate the antibiotic resistance of five foodborne Escherichia coli clinical isolates to ciprofloxacin, gentamicin and ampicillin. Methods: Based on the theory of electron transfer during bacterial energy metabolism and the introduction of resazurin as a redox probe, an electrochemical square wave voltammetry （SWV） method based on bladed tensin-mediated rapid identification of E. coli drug resistance was established. Results: The electrochemical square wave voltammetry values of E. coli at different concentrations mediated by resazurin were determined, and there was a good linear relationship between the E. coli concentration and the oxidized peak current （I） of resazurin in …

Determination Of Six Human Milk Oligosaccharides In Dairy Product By Precolumn Derivatization High Performance Liquid Chromatography With Fluorescence Detection, Li Qiqi, Huang Jiale, Mu Shuyi, Li Qishan, Huang Jingjun

Food and Machinery

Objective: To astablish a strong popularity, high sensitivity of six human milk oligosaccharides in dairy product by precolumn derivatization high performance liquid chromatography-fluorescence method. Methods: Aquatic product sample was precipitated with glacial acetic acid, filtration by using the filter paper. It was derived by 2-aminobenzamide solution. The extracts were centrifuged and filtered by using the organic filter membrane and analyzed by using a AdvanceBio Glycan Map column to be separated and detected，employing acetonitrile-50 mmol/L ammonium formate solution （pH 4.4） as the mobile phase for gradient elution. Results: Under the experimental conditions, six human milk oligosaccharides in dairy product were linear …