Digital Commons Network^™

A Transformational Agenda For National Security, Maryam Jamshidi

University of Chicago Legal Forum

Past efforts to "reimagine" national security in legal scholarship have largely avoided systematic engagement with the foundational assumptions and presumptions of the field. Challenging and critiquing those assumptions is, however, necessary to producing scholarly work that reimagines, rather than reproduces, status quo approaches to U.S. national security. This Article presents an agenda for reimagining national security through legal scholarship, which is premised on the view that challenging the national security status quo should be part of those efforts. In doing so, this agenda explores seven premises central to how U.S. national security is currently conceived of, practiced, and implemented. Moving …

Addressing Ip And Technology Challenges To Pandemic Protection: A Need For Global Coordination To Promote National Security, Cynthia M. Ho

University of Chicago Legal Forum

This Article argues that effective national security mandates protection against the spread of infectious diseases, which requires addressing intellectual property (IP) and technology obstacles. Without modification, IP laws can bar the manufacture of needed treatments by anyone besides the IP owner and its licensees. Although there was some recognition during the COVID-19 pandemic that existing IP laws should be modified, there was strong resistance not only by IP-owning companies, but also by individual countries that impeded the ability to manufacture needed vaccines during the height of the pandemic.

Many global leaders have recognized that future pandemics are inevitable and that …

Coronavirus Disease 2019 (Covid-19) Real World Data Infrastructure: A Big-Data Resource For Study Of The Impact Of Covid-19 In Patient Populations With Immunocompromising Conditions, James M. Crawford, Lynne Penberthy, Ligia A. Pinto, Keri N. Althoff, Magdalene M. Assimon, Oren Cohen, Laura Gillim, Tracy L. Hammonds, Shilpa Kapur, Harvey W. Kaufman, David Kwasny, Jean W. Liew, William A. Meyer 3rd, Shannon L. Reynolds, Cheryl B. Schleicher, Suki Subbiah, Catherine Theruviparampil, Zachary S. Wallace, Jeremy L. Warner, Suhyeon Yoon, Yonah C. Ziemba

School of Medicine Faculty Publications

Background. We developed a United States–based real-world data resource to better understand the continued impact of the coronavirus disease 2019 (COVID-19) pandemic on immunocompromised patients, who are typically underrepresented in prospective studies and clinical trials. Methods. The COVID-19 Real World Data infrastructure (CRWDi) was created by linking and harmonizing de-identified HealthVerity medical and pharmacy claims data from 1 December 2018 to 31 December 2023, with severe acute respiratory syndrome coronavirus 2 virologic and serologic laboratory data from major commercial laboratories and Northwell Health; COVID-19 vaccination data; and, for patients with cancer, 2010 to 2021 National Cancer Institute Surveillance, Epidemiology, and …

Reduced Autoimmunity Associated With Deletion Of Host Cd73, Beanna Okeugo, Shabba A Armbrister, Rhea C Daniel, Zeina M Saleh, Jessica Wang, Salomea Giorgberidze, J Marc Rhoads, Yuying Liu

Faculty, Staff and Student Publications

CD73 is ubiquitously expressed and regulates critical functions across multiple organ systems. The sequential actions of CD39 and CD73 accomplish the conversion of adenosine triphosphate to adenosine and shift the adenosine triphosphate-driven proinflammatory immune cell milieu toward an anti-inflammatory state. This immunological switch is a major mechanism by which regulatory T (Treg) cells control inflammation. Foxp3 engages in Treg development and function. Foxp3 mutations result in the scurfy (SF) mouse phenotype and a rapidly lethal lymphoproliferative syndrome. We generated double knockout (KO) mouse (CD73KOSF) by breeding heterozygous Foxp3sf/J females to CD73KO male mice to remove host CD73. We initially aimed …

Earthing Practice For Mental Health Among Adults In The United States: A Phenomenological Inquiry, Natalie Greenberg

Dissertations

This study aimed to explore the lived experience of adults in the United States who practice earthing for mental health.

Forecasting The Impact Of Artificial Intelligence On Clinical Pharmacy Practice, Adrian Wong Pharmd, Mph, Fccp, Trenton Flanagan Pharmd, Elizabeth W. Covington Pharmd, Elaine Nguyen Pharmd, Mph, Mba, Dustin D Linn Pharmd, Mba, Gretchen Brummel Pharmd, Brian Hoffmaster Pharmd, Mba, Diana Issacs Pharmd, Fccp, Sandra L. Kane-Gill {Harmd, Msc, Fccp

Parkview Pharmacy Department

There is a need to understand contemporary scientific advances as clinical pharmacy evolves. One rapidly expanding area is artificial intelligence (AI), which has grown significantly over the past year because of the public availability of large language models. This commentary reviews published literature describing and evaluating applications of AI to each aspect of the medication use process and forecasts potential future roles for AI in pharmacy practice. Potential challenges in implementation are also described.

Anthropological Analysis Of The Human Skeletal Remains From Naḥalat Ahim, Jerusalem (Pp. 121–124), Joe Zias

'Atiqot

The remains of 51 individuals were recovered from a Byzantine-period tomb at Naḥalat Ahim: 47% were adults, 40% were sub-adults and 4% were between 6–12 months; no neonates were identified. There was no discernible demographic pattern regarding age, sex or place of burial within the tomb. Two benign bone tumors were found in two different individuals; both types are previously unreported in excavations in Israel.

Human Skeletal Remains From A Second -Temple-Period Tomb In Arnona, Jerusalem (Pp. 117–120), Joe Zias

'Atiqot

A minimum of 41 individuals was recovered from the tomb. The demographic profile shows that 51% of the population died before age 18, in accord with other reported figures from the period. The pathology of the interred is unique, representing the first reported incident of tuberculosis in an ancient Jewish population.

Geographic Disparities Impacting Oral Vaccine Performance: Observations And Future Directions, Rachel M Burke, Sasirekha Ramani, Julia Lynch, Laura V Cooper, Haeun Cho, Ananda S Bandyopadhyay, Carl D Kirkwood, A Duncan Steele, Gagandeep Kang

Faculty, Staff and Students Publications

Oral vaccines have several advantages compared with parenteral administration: they can be relatively cheap to produce in high quantities, easier to administer, and induce intestinal mucosal immunity that can protect against infection. These characteristics have led to successful use of oral vaccines against rotavirus, polio, and cholera. Unfortunately, oral vaccines for all three diseases have demonstrated lower performance in the highest-burden settings where they are most needed. Rotavirus vaccines are estimated to have >85% effectiveness against hospitalization in children < 12 months in countries with low child mortality, but only ~65% effectiveness in countries with high child mortality. Similarly, oral polio vaccines have lower immunogenicity in developing country settings compared with high-resource settings. Data are more limited for oral cholera vaccines, but suggest lower titers among children compared with adults, and, for some vaccines, lower efficacy in endemic settings compared with non-endemic settings. These disparities are likely multifactorial, and available evidence suggests a role for maternal factors (e.g. transplacental antibodies, breastmilk), host factors (e.g. genetic polymorphisms-with the best evidence for rotavirus-or previous infection), and environmental factors (e.g. gut microbiome, co-infections). Overall, these data highlight the rather ambiguous and often contradictory nature of evidence on factors affecting oral vaccine response, cautioning against broad extrapolation of outcomes based on one population or one vaccine type. Meaningful impact on performance of oral vaccines will likely only be possible with a suite of interventions, given the complex and multifactorial nature of the problem, and the degree to which contributing factors are intertwined.

Children Rights To "Zero Hunger" And The Execution Challenges During The Covid-19 Crisis, Nurul Hidayat Binti Ab Rahman, Redwan Bin Yasin

Hasanuddin Law Review

Zero hunger is the world's pledge under the Sustainable Development Goals 2030, which aims to end hunger, achieve food security and improve nutrition. Nevertheless, the mission had been seized as the world faced economic turndown due to the outbreak of the COVID-19 virus. The circumstances have brutally affected societies ideal living standards and raised social problems such as extreme poverty, famishment, malnutrition, and medical conditions, specifically among vulnerable children. The essential purpose of this writing is to elucidate the zero hunger goal as one of the central legal rights and identify challenges in executing it during the COVID-19 crisis. Data …

Legal Reforms In Indonesia’S Financial Sector On Institutional Relations Between Bank Indonesia And The Government, R. Dwi Tjahja K. Wardhono, Dian Puji Nugraha Simatupang, Nadhia Shalehanti

Hasanuddin Law Review

Legal reform in the financial sector has an important role to play in preparing Indonesia a Golden Indonesia in 2045. The financial sector is very important strategic in the development and welfare Indonesia, supporting its sustainable economic development. Strengthening institutional functions and tasks as well as coordination among ministries and institutions, in this case between the central bank and the government, are essential in order to increase financial system resilience and economic growth. This study analyses financial sector legal reforms that impact institutional relations between central banks and governments by conducting comparative studies of the United States, Japan, Australia, and …

Will Formalities During The Pandemic: A Comparative Study Of Malaysia And Selected Jurisdictions, Gary Kit Min Ng, Chee Ying Kuek, Eng Siang Tay, Francesca Nyuk Oi Chin, Joanne En Ling Lau

Hasanuddin Law Review

Most countries around the world have entered the endemic stage of the novel coronavirus after 2 years of battling with the soaring rise of infections among the people. As of 1 April 2022, Malaysia, a country which has one of the highest rates of infection per capita in Southeast Asia, has entered the endemic phase of Covid-19. For a will to be valid in Malaysia, the formalities in the Wills Act 1959 (Revised 1998) must be strictly conformed to. A slight deviation from the formalities would render invalid the will that conveys the testamentary intention of the testator. The Covid-19 …

Moud 2.0: A Clinical Algorithm And Implementation Evaluation Protocol For Sublingual And Injectable Buprenorphine Treatment Of Opioid Use Disorder, Brandon Joa, Eric Fung, Michael Weinstein, Lara Weinstein

Department of Family & Community Medicine Faculty Papers

BACKGROUND: Primary care is the initial contact point for most patients with opioid use disorder (OUD) but lacks tools for guiding treatment. Only a small fraction of patients access evidence-based care. Long-acting injectable buprenorphine has potential to improve medication adherence and program retention in low-barrier primary care treatment settings. We present the first clinical decision support algorithm incorporating long-acting buprenorphine (LAIB) in primary care. We include a protocol for a future evaluation of the algorithm's implementation process, "Medication for Opioid Use Disorder (MOUD) 2.0," at a housing and integrated care clinic at a Federally Qualified Health Center.

METHODS: Literature review …

Legal Protection For Domestic Workers: The Experience Of Indonesia, Sakka Pati

Hasanuddin Law Review

Given its social and economic invisibility and the accompanying low social status, domestic work is often exploitative. This research was aimed to find out and formulate the substance of legal protection for domestic workers in legislation in the field of labor in terms of the perspective of justice. It uses a statute, case, and socio-legal approaches. It was conducted in 3 (three) major cities, namely Jakarta, Yogyakarta and Makassar. The results of research showed that the substance of legal provisions in general for the protection of domestic workers, especially in labor legislation basically has not been able to guarantee justice …

Equal Access To The Vaccination Of Covid-19 In Southeast Asia: Can Asean Be A Catalyst?, Muhammad Insan Tarigan, Raisha Hafandi

Hasanuddin Law Review

Since the time Covid-19 was discovered in Southeast Asia, around 2.5 million people have been infected and more than 54 thousand have died by early March 2021. Even though ASEAN members have followed most of the WHO recommendations to deal with Covid-19, cases are still liable to increase. Therefore, vaccine utilization is the best chance which people believe in to fight the pandemic for now. However, the vaccine’s availability and distribution are a dilemma for the ASEAN member countries. Therefore, this article aims to determine the possibility of ASEAN’s role in creating equal access to the Covid-19 vaccine for everyone. …

The Lived Experiences Of Nonprofit Managers In Post-Covid Pandemic Recovery, Alonzo Curry

Walden Dissertations and Doctoral Studies

Nonprofit managers have been tasked with making difficult and creative decisions in the post-COVID-19 pandemic era. Policymakers, donors, and sector stakeholders need to understand the specific challenges nonprofit managers face during crises. The purpose of this qualitative hermeneutic phenomenological study was to understand the post-COVID-19 crisis management experiences of nonprofit managers in the United States and identify how nonprofit managers made meaning of such experiences. The research question for this qualitative exploration was based on the lived experiences of nonprofit managers with managing crises during the post-COVID-19 pandemic. This qualitative hermeneutic phenomenological study was developed with a multicultural theoretical foundation. …

The Lived Experiences Of Nonprofit Managers In Post-Covid Pandemic Recovery, Alonzo Curry

Walden Dissertations and Doctoral Studies

Nonprofit managers have been tasked with making difficult and creative decisions in the post-COVID-19 pandemic era. Policymakers, donors, and sector stakeholders need to understand the specific challenges nonprofit managers face during crises. The purpose of this qualitative hermeneutic phenomenological study was to understand the post-COVID-19 crisis management experiences of nonprofit managers in the United States and identify how nonprofit managers made meaning of such experiences. The research question for this qualitative exploration was based on the lived experiences of nonprofit managers with managing crises during the post-COVID-19 pandemic. This qualitative hermeneutic phenomenological study was developed with a multicultural theoretical foundation. …

The Implementation Of Right-Fulfillment To The Health Care In Achieving The Millennium Development Goal (Mdg’S), Muhammad Zuhri, Basri Basri

Hasanuddin Law Review

The vision of Aceh Government in 2012-2017 is Aceh are dignified, prosperous, just, and independent based on the legislation of Aceh government as a form of Memorandum of Understanding. One of the visions of Aceh government 2012- 2017 is the improved welfare of Acehnese people through quality health services through increasing life expectancy, infant mortality, decreasing the prevalence of malnutrition as well as the effectiveness of the treatment of infectious diseases to the achievement of the MDG’s. Model policies adopted by the Aceh government is monitoring and track record of cases, tv monitor, routine and case sms, a special program …

Problematic Policy: Environmental Impacts Of Traditional Mining In Papua, Hotlan Samosir

Hasanuddin Law Review

Mining without permits has changed land cover in the mining area. The activities of people mining without permits have violated the principle of sustainable development, where the economic aspects take precedence over ecological and social aspects. The research is a normative-legal research using a statute, case and conceptual approaches. The research conducted in Nabire Regency, Papua, Indonesia. The results show that The activities of gold mining in Nabire regency which have been going on for decades have not been well-organized. The implementation of people mining has caused environmental damage, especially in the mining area. The environmental damage due to the …

Animal Welfare And Covid-19 In Indonesia: A Neglected Legal Issue, Myrna Asnawati Safitri, Firman Firman

Hasanuddin Law Review

The Covid-19 pandemic currently infecting the world population comes from the Coronavirus (SARS-CoV-2) transmitted initially from animals to humans, then between humans. This disease is referred to as zoonosis. Covid-19 discourse is generally about zoonotic transmission from animals to humans. Not much attention has been given to the potential transmission from humans to animals. In several countries, cases indicating the exposures of animals with the Coronavirus have been found. Thus, a discussion on the vulnerability of exposure to animals with the Coronavirus is significant to scientifically discussed. Unfortunately, concerns about this problem are still voiced by the mass media. Limited …

The Law In The Face Of The Covid-19 Pandemic: Early Lessons From Uruguay, Nima Norouzi, Heshmat-Ullah Khanmohammadi, Elham Ataei

Hasanuddin Law Review

The Corona crisis is one of the crises that has engulfed the world and Uruguay and has marked all human beings' death and life. This crisis has many legal, political, social, and economic dimensions and has and will have different consequences in this area. So far in the last two centuries, twelve major epidemics of infectious diseases and fifteen famines, and severe droughts have engulfed our world, but this crisis is "of a different kind." It has been less critical to cover the whole world. Infect millions of people, create new words in cultures, and announce major changes in international …

Management And Outcome Of Invasive Clindamycin-Resistant Mrsa Community-Associated Infections In Children, Amanda E Macias, Grant Stimes, Sheldon L Kaplan, Jesus G Vallejo, Kristina G Hulten, J Chase Mcneil

Faculty, Staff and Students Publications

Background: Clindamycin resistance among community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) complicates the management of a challenging infection. Little data exist to guide clinicians in the management of invasive clindamycin-resistant CA-MRSA infections in children and studies using oral regimens such as trimethoprim-sulfamethoxazole (TMP-SMX) and linezolid for treatment of these infections are limited. We sought to reevaluate antibiotic management among invasive CA-MRSA at a tertiary children’s hospital.

Methods: Cases of invasive clindamycin-resistant MRSA infections in children were identified through an ongoing S. aureus surveillance study. Eligible cases were those occurring in otherwise healthy children from 2011–2021. Medical records were reviewed.

Results: Thirty-four subjects …

Resurgence Of Pediatric Mycoplasma Pneumoniae Infections In Southeast Texas, November 2023-June 2024, Margaret Taylor Danner, Heather Colvin Binns, Khanh Nguyen, Coreen Johnson, Jim Dunn, Denver Niles, Diana K Nguyen

Faculty, Staff and Students Publications

We conducted a retrospective review of children tested for Mycoplasma pneumoniae from January 1, 2020 to June 30, 2024. M. pneumoniae polymerase chain reaction positivity increased starting in November 2023, peaking at 18.3% in June 2024. During the resurgence, children with laboratory-confirmed infection often had severe respiratory disease or extrapulmonary manifestations.

Decriminalizing Disease: A Health Justice Approach To Infectious Diseases And Criminal Law, Sean E. Bland

Arkansas Law Review

Infectious diseases, also called communicable diseases, are largely a public health issue and should not be criminalized. This Article seeks to re-frame the discussion around the legal framework for infectious diseases in a way that moves beyond a punishment mindset and toward a health justice mindset. The focus in this Article is on health justice rather than traditional understandings of public health, defined as the science and practice of improving the health of people and their communities. The Article makes three novel contributions. First, it applies a health justice framework to the critique of infectious disease criminalization. Second, the Article …

Contents, Journal Editors

Arkansas Law Review

No abstract provided.

Arkansas Law Review - Volume 77 Issue 3, Journal Editors

Arkansas Law Review

No abstract provided.

Niaid Workshop Report: Systematic Approaches For Eskape Bacteria Antigen Discovery, Inka Sastalla, Keehwan Kwon, Clayton Huntley, Kimberly A. Taylor Dnp, Rn, Nea-Bc, Cnor, Clssbb, Liliana Brown, Tamika Samuel, Lanling Zou

Publications

On 14-15 November 2023, the National Institute of Allergy and Infectious Diseases (NIAID) organized a workshop entitled "Systematic Approaches for ESKAPE Bacteria Antigen Discovery". The goal of the workshop was to engage scientists from diverse relevant backgrounds to explore novel technologies that can be harnessed to identify and address current roadblocks impeding advances in antigen and vaccine discoveries for the ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species). The workshop consisted of four sessions that addressed ESKAPE infections, antigen discovery and vaccine efforts, and new technologies including systems immunology and vaccinology approaches. Each …

Development And Validation Of A Home-Based Exercise Program Integrated With Patient Education Based On The Health Belief Model For Patients With Type 2 Diabetes Mellitus, Amirah Mustapa, Alia Alghwiri, Haidzir Manaf

Internet Journal of Allied Health Sciences and Practice

Purpose: The purpose of this study is to develop and validate a comprehensive approach that integrates an exercise routine with patient education based on the health belief model (HBM) approach to promote effective exercise in this population. Method: A 3-phase study was conducted. In Phase I, two comprehensive scoping reviews were performed to develop the program. An initial draft of the program consisted of exercise protocols and HBM-based education. In Phase II, nine experts were chosen to further develop and refine the program’s content by providing feedback and validating it using the content validity index (CVI) and the Patient Education …

How Did Covid-19 Impact Physiology Research Globally? – Lessons Learned And Future Recommendations, Jeet Patel, Santanu De

Mako: NSU Undergraduate Student Journal

The Coronavirus Infectious Disease 2019 (COVID-19) pandemic caused massive changes in the medical field across the globe. As the whole world moved from in-person to remote activities, students found themselves in a predicament where they were compelled towards schooling and work online from home. This would mean that all projects, research, tests, and meetings were conducted over Zoom or other online meeting platforms. Laboratories were shut down or only a limited number of people were allowed to enter to conduct the necessary research. This paper discusses how the COVID-19 pandemic affected research process and experiments within various aspects of the …

Understanding Covid-19 Vaccination Hesitance Among Registered Nurses, Lucille Fenelon

Walden Dissertations and Doctoral Studies

The development of the COVID-19 vaccine, while hailed as a groundbreaking scientific achievement, also brought to light a discernible hesitance from registered nurses (RNs) regarding the vaccination. While extensive research has delved into the broader phenomenon of vaccination hesitancy, there remains a notable gap in comprehensively examining the specific lived experiences of RNs in relation to this hesitancy. Thus, the purpose of this study was to explore the lived experiences of RNs contributing to COVID-19 vaccine hesitance within the context of the theory of reasoned action (TRA) and Roy’s adaptation model. TRA helped to guide this study in identifying the …