Digital Commons Network^™

Consideration On The Coordinated And Synergistic Role Of Science And Technology In Responding To Major Public Health Emergencies, Xia Junjie, Yang Ming

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Cefazolin Inoculum Effect And Methicillin-Susceptible Staphylococcus Aureus Osteoarticular Infections In Children, J Chase Mcneil, Lauren M Sommer, Mary Boyle, Patrick Hogan, Jesus G Vallejo, Kristina G Hultén, Anthony R Flores, Sheldon L Kaplan, Stephanie Fritz

Open Access Publications

Select methicillin-susceptible

Adherence To Hiv Antiretroviral Therapy Among Pregnant And Postpartum Women During The Option B+ Era: 12-Month Cohort Study In Urban South Africa And Rural Uganda, Lynn T. Matthews, Catherine Orrell, Mwebesa B. Bwana, Alexander C. Tsai, Christina A. Psaros, Stephen Asiimwe, Gideon Amanyire, Nicholas Musinguzi, Kathleen Bell, David Bangsberg, Jessica E. Haberer

OHSU-PSU School of Public Health Faculty Publications and Presentations

Introduction: We conducted a cohort study to understand patterns of anti-retroviral therapy (ART) adherence during pregnancy, postpartum and non-pregnancy follow-up among women initiating ART in public clinics offering Option B+ in rural Uganda and urban South Africa. Methods: We collected survey data, continuously monitored ART adherence (Wisepill), HIV-RNA and pregnancy tests at zero, six and twelve months from women initiating ART in Uganda and South Africa, 2015 to 2017. The primary predictor of interest was follow-up time categorized as pregnant (pregnancy diagnosis to pregnancy end), postpartum (pregnancy end to study exit) or non-pregnancy-related (neither pregnant nor postpartum). Fractional regression …

The Extended Bch Model For Cure Rate Estimation Using Right Censored Data, Bader Aljawadi

Hebron University Research Journal-A (Natural Sciences) - (مجلة جامعة الخليل للبحوث- أ (العلوم الطبيعيه

In cancer clinical trials, a significant proportion of patients can be cured, that is, the symptoms of the disease are completely eliminated, so that it never recurs. In this article the focus is on the estimation of the proportion of patients who are cured. The non-parametric maximum likelihood estimation method is used for cure rate estimation considering the extended bounded cumulative hazard (BCH) model. We will consider the cure rate estimation using right censoring. The analysis shows the analytical solution of the estimating equations via the EM algorithm followed by a simulation study

2020-08-19_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

We Are...Marshall, August 19, 2020, Office Of Marshall University Communications

We Are ... Marshall: the Newsletter for Marshall University 1999-2023

No abstract provided.

Dectin-1 Mediated Mechanical Force Generation In Candida Albicans Fungal Pathogen Recognition, Rohan Choraghe

Biomedical Engineering ETDs

Candida spp. pathogens continue to be a major health care burden with high mortality and exceeding a billion dollars in terms of healthcare cost. Candidainfection ranges from superficial dermatological infection to more serious blood stream infection in debilitated patients. One of the major lines of innate immune defense against Candidais phagocytosis. Dectin-1 is the antifungal receptor in myeloid cells responsible for most immune responses against fungi including phagocytosis. We looked into the signaling pathway coordinating this mechanical process downstream of Dectin-1. We found that Dectin-1 activation gives rise to a significant mechanical force generation mediated through RHOA-ROCK-MyosinII pathway. …

Increasing Provider Awareness To Detect, Treat, And Reduce Sexually Transmitted Infections In Male Service Members, Vincent E. Krause

Dissertations

The incidence of sexually transmitted infections within the military continues to rise at rates higher than that of the civilian population. The project was developed to improve provider perception related to the male patient's sexual history, practices, and attitudes and focus on adherence to the recommended guidelines related to screening for sexually transmitted infections (STIs), specifically Chlamydia trachomatis and Neisseria gonorrhoeae. Education was provided regarding recommended screening criteria, screening protocols, interview techniques, screening options available, and statistical data. The goal was to increase provider awareness and laboratory diagnosis of STI screenings among the male population, reducing chlamydia and gonorrhea infections …

Hamman-Rich Syndrome: A Diagnosis Of Exclusion In The Covid-19 Pandemic., Qian Zhang, Ahmad Raza, Vincent Chan, Artem Minalyan, John Madara, Md

Abington Jefferson Health Papers

Hamman-Rich syndrome is a rapidly progressive interstitial lung disease with acute respiratory distress syndrome physiology. It carries a grave prognosis and a high early mortality rate. It is often distinguished from other similar pulmonary pathologies based on the clinical course, laboratory findings, bronchoalveolar lavage testing, and pathology report. We detail a 77-year-old lady with no prior pulmonary disease, smoking history, or occupational and environmental exposures present to the emergency department found to be in acute hypoxic respiratory failure with impressive progressive radiographic findings. The presumptive diagnosis of Hamman-Rich syndrome was made based on a combination of factors after ruling out …

The Emotional Impact Of The Covid-19 Pandemic On Individuals With Progressive Multiple Sclerosis, Nancy D. Chiaravalloti, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Ulrik Dalgas, John Deluca, Cecilia Meza, Nancy B. Moore, Peter Feys, Massimo Filippi, Jennifer Freeman, Matilde Inglese, Rob Motl, Maria Assunta Rocca, Brian M. Sandroff, Amber Salter, Gary Cutter, Anthony Feinstein

School of Health Professions

No abstract provided.

A Case Report Of Bullous Subconjunctival Hemorrhag In Adenoviral Conjunctivitis, Sean Haynie, Jesse Johnson, Md

The Medicine Forum

A 78-year-old female with a past medical history of optic neuropathy and atrial fibrillation on warfarin presented with two weeks of progressive bilateral eye redness, swelling, pain, and blurry vision.

Table Of Contents: The Medicine Forum Volume 21, 2019-2020

The Medicine Forum

Table of Contents: The Medicine Forum Volume 21, 2019-2020

2020-08-18_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

2020 August 18 - Faculty Senate Agenda And Minutes, Faculty Senate, East Tennessee State University

Faculty Senate Agendas and Minutes

No abstract provided.

Responding To Questions Of Parents With Vaccine Concerns, Chalea Rowberry

Student Works

ABSTRACT

Introduction: Even with the benefits of vaccinations, some parents refuse vaccinations due to influence from vaccine opponents. The purpose of this article is to identify common vaccine concerns on public forums and address these concerns with scientific evidence, thereby offering PNPs information on how to respond.

Method: Six electronic databases were searched to identify articles examining concerns of parents regarding vaccines and provide evidence-based responses to each concern.

Results: Some parents are concerned that healthcare providers are not obtaining written informed consent prior to vaccinating their child(ren). Another common concern is that pharmaceutical companies are solely motivated by financial …

Chronic Rhinotillexomania Leading To Multiple Infectious Sequelae In A 66-Year-Old Female, Kunal Shah, Praveen Sankrithi, Sanket Shah, Mark A. Smith

Student Publications

Rhinotillexomania, more commonly known as nose-picking, is a body-focused repetitive behavior that involves compulsive picking of the nares. While nose-picking in general is a common and largely unharmful practice worldwide, severe complications from chronic nose-picking do exist. This case highlights a 66-year-old female with a longstanding history of nose-picking and nose blowing who presented to the emergency department with acute delirium and various bodily complaints. She was subsequently admitted multiple times for recurrent sepsis, meningitis, endocarditis, cystitis, and discitis with each culture positive for methicillin-sensitive Staphylococcus aureus (MSSA) with identical antibiotic sensitivities. Further imaging failed to reveal an underlying greater …

Effect Of Covid-19 Pandemic On The Cardiac Outpatients’ Perception Of Seeking Medical Advice, Sondos Samargandy, Turki A. Al Garni, Abdulrahman Almoghairi, Mohammed Alahmari, Bandar Alshehri, Mohammed Mosaad, Jamal Ahmed, Hussein Alamri, Shaza Samargandy

Journal of the Saudi Heart Association

Background:

During this unprecedented time of COVID-19 pandemic, it was noticed a decline in cardiovascular cases presentation to the Emergency rooms in many countries, raising many speculations about the reasons and its ramifications?

Objectives:

1-Identify the reasons during this pandemic that refrain patients from seeking medical care and its impact on stress level and medication adherence.

2- emphasize the new role of virtual medicine.

Methods:

A quantitative descriptive cross-section survey study of 388 patients. It has been done in the cardiac outpatient department and conducted virtually through telemedicine.

Results:

Despite this pandemic and its consensuses, the majority of cardiac outpatients …

Bibliometric Analysis Of Bioscience Trends Journal (2007-2017): Knowledge Dynamics And Visualization, Anis Fuad, Yuan-Chii Gladys Lee, Chien-Yeh Hsu

Library Philosophy and Practice (e-journal)

BioScience Trends (BST) is a peer-reviewed journal belongs to the International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA) Group of Japan. Despite a decade of existence, no study was performed to measure the bibliometric profile of the journal. The objective of this study was to investigate the bibliometric characteristic of BST. A bibliometric analysis will specifically measure: 1) growth rate of the scientific publications, 2) dynamics of authorship and collaboration pattern; 3) core research themes of articles that have been published, and 4) citation pattern of BST. Bibliographical archives of BST were obtained from the Core Collection …

Provost Newsletter - August 14, 2020, Office Of The Provost, Wright State University

Office of the Provost Newsletters and Announcements

The Newsletter from the Office of the Provost regarding specifics about the plans and process in place for the 2020 Fall Semester.

2020-08-17_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Should You Get Covid Antibody Testing? And What Do The Results Mean? Uab Experts Respond., Matt Windsor

Browse All News

No abstract provided.

Assessing Adverse Effects Of Mercury In Two Pinniped Species, Marianne Lian

Interdisciplinary Studies

This dissertation studies measures of adverse effects in free-ranging pinnipeds associated with relatively high total mercury ([THg]) or monomethylmercury ([MeHg+]) concentrations, relatively low total selenium ([TSe]) concentrations and/or low TSe:THg molar ratios. Both the Steller sea lion (SSL, Eumetopias jubatus) and Pacific harbor seal (HS, Phoca vitulina richardii) inhabit coasts of the North Pacific, and are considered important sentinel species for One Health (environmental, animal and human health). Relatively high [THg] is reported for some animals in both species, causing concern for adverse effects especially in the developing fetus. Maternal piscivorous diet can expose the fetus to MeHg⁺ at a …

Sea Urchin Ecology: Effects Of Food-Web Modification, Climate Change, And Community Structure, Benjamin P. Weitzman

Marine Biology

Ecosystem structure and function of temperate rocky reef habitats are subject to change as a result of food-web modification, climate change, and changes in biological community interactions. Sea urchins are a global driver of change in nearshore marine habitats though their ability to heavily graze marine vegetation and force rocky reef ecosystems from kelp forest to sea urchin barren ground states. The Aleutian Archipelago in southwest Alaska provided an ideal natural laboratory to study sea urchin (Strongylocentrotus spp.) ecology following the functional loss of the keystone predator, the sea otter (Enhydra lutris) during the 1990s. The objectives of this dissertation …

2020 Convocation, Eric Pan '21, José M. Torres, Comfort Akwaji-Anderson, Lynn Sosa-Bergeron '94

Convocation

• Welcome: Katie Berger, Chief Student Affairs Officer
• Pledge of Allegiance: Eric Pan '21, Student Council President
• Opening Remarks: José M. Torres, Ph.D., President
• Opening Remarks: Comfort Akwaji-Anderson, Ph.D., Principal
• Featured Musical Selection: "The Good Times" by Renzo Ledesma ‘19 and Hieu Nguyen ‘17
• Keynote Address: Lynn Sosa-Bergeron ‘94
• Closing Remarks: Comfort Akwaji-Anderson, Ph.D., Principal

Cd300lf Polymorphisms Of Inbred Mouse Strains Confer Resistance To Murine Norovirus Infection In A Cell Type-Dependent Manner, Kevin Furlong, Scott B. Biering, Jayoung Choi, Craig B. Wilen, Robert C. Orchard, Christiane E. Wobus, Christopher A. Nelson, Daved H. Fremont, Megan T. Baldridge, Glenn Randall, Seungmin Hwang

Open Access Publications

Human norovirus is the leading cause of gastroenteritis worldwide, yet basic questions about its life cycle remain unanswered due to an historical lack of robust experimental systems. Recent studies on the closely related murine norovirus (MNV) have identified CD300LF as an indispensable entry factor for MNV. We compared the MNV susceptibilities of cells from different mouse strains and identified polymorphisms in murine CD300LF which are critical for its function as an MNV receptor. Bone marrow-derived macrophages (BMDMs) from I/LnJ mice were resistant to infection from multiple MNV strains which readily infect BMDMs from C57BL/6J mice. The resistance of I/LnJ BMDMs …

Repurposed Agents In The Alzheimer's Disease Drug Development Pipeline, Justin Bauzon, Garam Lee, Jeffrey Cummings

School of Medicine Faculty Research

Background: Treatments are needed to address the growing prevalence of Alzheimer’s disease (AD). Clinical trials have failed to produce any AD drugs for Food and Drug Administration (FDA) approval since 2003, and the pharmaceutical development process is both time-consuming and costly. Drug repurposing provides an opportunity to accelerate this process by investigating the AD-related effects of agents approved for other indications. These drugs have known safety profiles, pharmacokinetic characterization, formulations, doses, and manufacturing processes. Methods: We assessed repurposed AD therapies represented in Phase I, Phase II, and Phase III of the current AD pipeline as registered on ClinicalTrials.gov as of …

Soil Characteristics Associated With Horse Cases Of Eastern Equine Encephalitis Virus In Florida, Fulya Guzelkucuk

USF Tampa Graduate Theses and Dissertations

Eastern Equine Encephalitis virus (EEEV) is a mosquito-borne virus found in Florida that affects humans and horses. Also, EEEV is an agricultural land management issue in Florida, as it causes mortality in large numbers of horses each year and sometimes humans. This study investigates the characteristics of soils associated with horse cases of EEEV in the State of Florida, focusing on differences in soil characteristics between summer and winter cases. This study analyzed a total of 676 EEEV cases during 2005-2018, including 611 summer cases and 65 winter cases. Soil characteristics that were examined include: soil texture, drainage class, hydrology …

Measles, Movements And Medical Exemptions: How California Learned To Lead The Way, Joseph Bishop

Madison Historical Review

In 2000, the United States celebrated the elimination of measles. Yet within twenty years, measles epidemics had sprung up throughout the country. This article examines the factors responsible for measles’ return to the United States and argues for a state policy that effectively reduces potential outbreaks. The growing anti-vaccination movement and vaccine misinformation largely account for the increase in vaccine hesitancy, leading to measles epidemics. California’s Senate Bill 277, a school-entry vaccination policy, demonstrates how withholding religious and philosophical exemptions increased vaccination rates in unprotected communities. By decreasing vaccine hesitancy with effective vaccine exemption policies, the United States can be …

Memantine Treatment Reduces The Incidence Of Flaccid Paralysis In A Zika Virus Mouse Model Of Temporary Paralysis With Similarities To Guillain-Barré Syndrome, Venkatraman Siddharthan, Hong Wang, Alexandre Lr De Oliveria, Xin Dai, John D. Morrey

Animal, Dairy, and Veterinary Science Faculty Publications

Clinical evidence suggests that Zika virus contributes to Guillain-Barré syndrome that causes temporary paralysis. We utilized a recently described Zika virus mouse model of temporary flaccid paralysis to address the hypothesis that treatment with an N-methyl-D-aspartate receptor antagonist, memantine, can reduce the incidence of paralysis. Aged interferon alpha/beta-receptor knockout mice were used because of their sublethal susceptibility to Zika virus infection. Fifteen to twenty-five percent of mice infected with a Puerto Rico strain of Zika virus develop acute flaccid paralysis beginning at days 8–9 and peaked at days 10–12. Mice recover from paralysis within a week of onset. In …

2020-08-16_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …