Digital Commons Network^™

A Multi-Institutional Analysis Of Sternoclavicular Joint Coverage Following Osteomyelitis, Sammy Othman, Omar Elfanagely, Saïd C Azoury, Geoffrey M Kozak, Jessica Cunning, Arturo J Rios-Diaz, Prashanth Palvannan, Patrick J. Greaney, Matthew Jenkins, Doraid Jarrar, Stephen J Kovach, John P Fischer

Department of Surgery Faculty Papers

BACKGROUND: Sternoclavicular joint (SCJ) osteomyelitis is a rare pathology requiring urgent intervention. Several operative approaches have been described with conflicting reports. Here, we present a multi-institutional study utilizing multiple surgical pathways for SCJ reconstruction.

METHODS: A multi-institutional retrospective cohort study was conducted to identify patients who underwent surgical repair for sternoclavicular osteomyelitis between 2008 and 2019. Patients were stratified according to reconstruction approach: single-stage reconstruction with advancement flap and delayed-reconstruction with flap following initial debridement. Demographics, operative approach, type of reconstruction, and postoperative outcomes were analyzed.

RESULTS: Thirty-two patients were identified. Mean patient age was 56.2±13.8 years and 68.8% were …

Pestilence And Other Calamities In Civilizational Theory: Sorokin, Mcneill, Diamond, And Beyond, Vlad Alalykin-Izvekov

Comparative Civilizations Review

This paper analyses the phenomenon of pestilence through paradigmatic and methodological lenses of several outstanding social scholars, including Pitirim A. Sorokin, William H. McNeill, and Jared M. Diamond. All three thinkers have advanced original, fundamental, and revolutionary paradigms regarding the profound role which infectious diseases played, are playing, and will continue to play in world history and culture. The phenomenon of pestilence is studied in the context of other major calamities. The relevant historic, as well as contemporary macro-level and long-term sociocultural research, is reviewed. The author advances a number of original concepts, as well as makes relevant projections into …

"The Day Of Realization": A Review Essay Of Abbie Gardner's The Spirit Lake Massacre And Captivity Of Abbie Gardner, James C. Schaap

Pro Rege

No abstract provided.

Incidence And Molecular Characterization Of Fungi And Yeast Isolated From Cultured Catfish And Nile Tilapia., Ola Hashem, Viola Zaki, Radwia Adawy

Mansoura Veterinary Medical Journal

Objective: To study the incidence and seasonal dynamics of different fungi affecting freshwater fishes in Lake Manzala as well as molecular identification of the isolated fungi. Animals: 300 Nile tilapia (Oreochromis niloticus) and 300 catfish (Clarias gariepinus). Design: Descriptive study. Procedures: Random samples of Oreochromis niloticus (O. niloticus) and Clarias gariepinus (C. gariepinus) were collected from Manzala fish farms. Clinical and postmortem examination of fish was applied. Isolation and identification of different fungi were performed by conventional methods.Furthermore, the molecular characterization of isolated fungi was carried out. Results: C. gariepinus had a higher rate of infection with different fungal species …

Context-Specific Challenges, Opportunities, And Ethics Of Drones For Healthcare Delivery In The Eyes Of Program Managers And Field Staff: A Multi-Site Qualitative Study, Vyshnave Jeyabalan, Elysée Nouvet, Patrick Meier, Lorie Donelle Phd, Rn, Fcan

Publications

Unmanned aerial vehicles (UAVs), also known as drones, have significant potential in the healthcare field. Ethical and practical concerns, challenges, and complexities of using drones for specific and diverse healthcare purposes have been minimally explored to date. This paper aims to document and advance awareness of diverse context-specific concerns, challenges, and complexities encountered by individuals working on the front lines of drones for health. It draws on original qualitative research and data from semi-structured interviews (N = 16) with drones for health program managers and field staff in nine countries. Directed thematic analysis was used to analyze interviews and identify …

Personality Affects Dynamics Of An Experimental Pathogen In Little Brown Bats, Quinn M.R. Webber, Craig K.R. Willis

KIP Articles

Host behaviour can affect host–pathogen dynamics and theory predicts that certain individuals disproportionately infect conspecifics during an epidemic. Consistent individual differences in behaviour, or personality, could influence this variation with the most exploratory or sociable individuals most likely to spread pathogens. We quantified exploration and sociability in little brown bats ( Myotis lucifugus ) and then experimentally manipulated exposure to a proxy pathogen (i.e. ultraviolet (UV) fluorescent powder) to test two related hypotheses: (i) more sociable and more exploratory individuals would be more likely to transmit infections to other individuals, and (ii) more sociable and more exploratory individuals uninfected with …

The Clinical Outcome Of Hiv Infection At A Tertiary Care Center In Riyadh, Saudi Arabia, Abeer M. Baadani, Sulafa Ballool, Salwa Alhemyadi, Lina Sallam, Eid Alsufyani, Alaa Alghamdi, Wafaa Alfahad

Saudi Medical Journal

Objectives: To investigate clinical characteristics and the outcome of people living with HIV (PLWHIV) at tertiary care center in Riyadh, Saudi Arabia. Methods: The present retrospective, observational study was carried between 2000-2019 at Prince Sultan Military Medical City (PSMMC), Riyadh, Saudi Arabia. The demographic and clinical characteristics of 137 PLWHIV patients were collected by reviewing the medical data record. Results: Of the total 137 PLWHIV, 78.8% were male and 21.2% were female. At care entry, the most opportunistic infections found were the cytomegalovirus infections. cytomegalovirus (CMV) infections in 13.8% of patients, tuberculosis (8%), AIDS associated malignancy (10.9%), hepatitis B (5.8%), …

Digital Contact Tracing Technologies In Epidemics: A Rapid Review

Saudi Medical Journal

No abstract provided.

Public Cleanliness Satisfaction Survey [2019], Paulin Straughan, Mathews Mathew

Research Collection School of Social Sciences

The Singapore Management University undertook the third wave of the Public Cleanliness Satisfaction Survey (PCSS) with 1716 Singapore resident respondents providing responses before the start of the Circuit Breaker.

The 2019 wave of the PCSS continued to reflect the overall satisfaction with public cleanliness in Singapore. Satisfaction with cleanliness and cleaning services has improved substantially across all domains.

Ninety three percent of survey respondents were satisfied with the cleanliness of public spaces that they had recently visited, a 9% increase from the findings in 2018.

There was a substantial increase in satisfaction with the cleanliness of food and beverage (F&B) …

Full Issue

Comparative Civilizations Review

No abstract provided.

Tuberculosis Of The Flexor Carpi Radialis Muscle - A Case Report, Shah Fahad, Naveed Baloch, Nasir Ud Din

Section of Orthopaedic Surgery

Tuberculosis involving almost any organ of the body is a major problem in developing countries. The most commonly affected site in tuberculosis is the lung. Of the extra pulmonary tuberculosis, musculoskeletal involvement accounts for 1-5% of the cases. Muscular involvement in tuberculosis is a rare manifestation of extra pulmonary tuberculosis. Unusual presentations often go undetected and are associated with a diagnostic and therapeutic delay. This case report presents tuberculosis of the flexor carpi radialis.

How I Treat Acute And Persistent Sickle Cell Pain., Samir K. Ballas

Cardeza Foundation for Hematologic Research

Sickle pain is the hallmark of sickle cell disease (SCD). It could be acute, persistent/relapsing, chronic, or neuropathic. Although there is a general consensus that pain is a major manifestation of SCD, there is a controversy as to the types of pain and their interrelationship between acute, chronic, relapsing, persistent, etc. This report first reviews the general approach to the management of acute vaso-occlusive crisis (VOC) pain, including education, counseling, pharmacotherapy, non-pharmacotherapy, and fluid therapy. This is followed by the presentation of five patients that represent typical issues that are commonly encountered in the management of patients with SCD. These …

Biographical Feature: Robin Patel, M.D.(C.M.), D(Abmm), F(Aam), Fidsa, Facp, Erik Munson

Clinical Lab Sciences Faculty Research and Publications

No abstract provided.

Covid-19: Postmortem Diagnostic And Biosafety Considerations, J Matthew Lacy, Erin G. Brooks, Joshua Akers, Danielle Armstrong, Lauren Decker, Adam Gonzalez, William Humphrey, Romana Mayer, Matthew Miller, Catherine Perez, Jose Antonio Ruiz Arango, Lakshmanan Sathyavagiswaran, Wendy Stroh, Suzanne Utley

Pathology Research and Scholarship

As a result of the 2019 novel human coronavirus (COVID-19) global spread, medical examiner/coroner offices will inevitably encounter increased numbers of COVID-19-infected decedents at autopsy. While in some cases a history of fever and/or respiratory distress (eg, cough or shortness of breath) may suggest the diagnosis, epidemiologic studies indicate that the majority of individuals infected with COVID-19 develop mild to no symptoms. Those dying with-but not of-COVID-19 may still be infectious, however. While multiple guidelines have been issued regarding autopsy protocol in cases of suspected COVID-19 deaths, there is some variability in the recommendations. Additionally, limited recommendations to date have …

Outcomes Of Outpatient Parenteral Antimicrobial Therapy With Ceftriaxone For Methicillin-Susceptible Staphylococcus Aureus Bloodstream Infections—A Single-Center Observational Study, Yasir Hamad, Lee Connor, Thomas C. Bailey, Ige A. George

Open Access Publications

Background:

Methods: Adult patients with methicillin-susceptible

Results: Of 243 patients included, 148 (61%) were discharged on ceftriaxone and 95 (39%) were discharged on either oxacillin or cefazolin. The ceftriaxone group had lower rates of intensive care unit care, endocarditis, and shorter duration of bacteremia, but higher rates of cancer diagnoses. There was no significant difference in the composite adverse outcome in the oxacillin or cefazolin group vs the ceftriaxone group (18 [19%] vs 31 [21%];

Conclusions: For patients with MSSA BSI discharged on OPAT, within the limitations of the small numbers and retrospective design we did not find a significant …

The Effect Of Exposure To Long Working Hours On Stroke: A Systematic Review And Meta-Analysis From The Who/Ilo Joint Estimates Of The Work-Related Burden Of Disease And Injury, Alexis Descatha, Bradley A Evanoff, Et Al

Open Access Publications

BACKGROUND: The World Health Organization (WHO) and the International Labour Organization (ILO) are developing joint estimates of the work-related burden of disease and injury (WHO/ILO Joint Estimates), with contributions from a large network of individual experts. Evidence from mechanistic data and prior studies suggests that exposure to long working hours may cause stroke. In this paper, we present a systematic review and meta-analysis of parameters for estimating the number of deaths and disability-adjusted life years from stroke that are attributable to exposure to long working hours, for the development of the WHO/ILO Joint Estimates.

OBJECTIVES: We aimed to systematically review …

Postinfectious Cerebellar Syndrome With Paraneoplastic Antibodies: An Association Or Coincidence?, Sajid Hameed, Mukesh Kumar, Pal Satyajit Singh Athwal, Sukhmanii Kahlon, Nimit Dalal

Section of Neurology

Cerebellar ataxia has a very broad differential diagnosis in adults, including paraneoplastic and postinfectious etiologies. We report a case of a 56-year-old male presented with right-sided cerebellar dysfunction preceded by fever and headache. He was diagnosed with subacute postinfectious cerebellar ataxia. Blood serology showed the presence of anti-amphiphysin and anti-Ri (ANNA-2, antineuronal nuclear autoantibody type 2) antibodies, which have a known association with cerebellar syndrome. The patient subsequently improved with the steroids. Although no evidence of an underlying tumor was found in the patient, the presence of the paraneoplastic antibodies remains a mystery. We suggest a probable association of these …

Molecular Characterization Of Plasmid-Mediated Non-O157 Verotoxigenic Escherichia Coli Isolated From Infants And Children With Diarrhea, Md Fazlul Karim Khan, Shah Samiur Rashid, Mohammad Nazmul, Hassan Maziz, Aizi Nor Mazila Ramli, Roesnita Baharuddin

Baghdad Science Journal

A significant increase in the incidence of non-O157 verotoxigenic Escherichia coli (VTEC) infections have become a serious health issues, and this situation is worsening due to the dissemination of plasmid mediated multidrug-resistant microorganisms worldwide. This study aims to investigate the presence of plasmid-mediated verotoxin gene in non-O157 E. coli. Standard microbiological techniques identified a total of 137 E. coli isolates. The plasmid was detected by Perfectprep Plasmid Mini preparation kit. These isolates were subjected to disk diffusion assay, and plasmid curing with ethidium bromide treatment. The plasmid containing isolates were subjected to a polymerase chain reaction (PCR) for investigating the …

Relationship Between Humidity And Physiology In Warm And Humid Conditions – A Literature Review, Yuliya Dzyuban

Research Collection School of Social Sciences

Change in precipitation patterns caused by global warming will likely increase humidity in some areas of the world. Moreover, populations in tropical climates with already high humidity levels can experience an added stress on their health and thermal comfort due to an amplifying effect of heat and moisture. Humidity is a generic term commonly used to describe moisture in the air. However, there are numerous variables that describe different properties of humid air that can be used in scientific studies. While relative humidity remains the most used, it has several shortcomings associated with its high correlation with air temperature. Thus, …

Relationship Between Humidity And Physiology In Warm And Humid Conditions: A Literature Review, Yuliya Dzyuban

Research Collection School of Social Sciences

Change in precipitation patterns caused by global warming will likely increase humidity in some areas of the world. Moreover, populations in tropical climates with already high humidity levels can experience an added stress on their health and thermal comfort due to an amplifying effect of heat and moisture. Humidity is a generic term commonly used to describe moisture in the air. However, there are numerous variables that describe different properties of humid air that can be used in scientific studies. While relative humidity remains the most used, it has several shortcomings associated with its high correlation with air temperature. Thus, …

Determinants Of Health Care Seeking Behaviors In Puerperal Sepsis In Rural Sindh, Pakistan: A Qualitative Study, Shabina Ariff, Fatima Mir, Farhana Tabassum, Farrukh Raza, Atif Habib, Ali Turab, Amnesty Lefevre, Linda A. Bartlett, Sajid Bashir Soofi, Zulfiqar Ahmed Bhutta

Department of Paediatrics and Child Health

Background: Puerperal sepsis (PS) is one of the major causes of maternal death, contributing to 26,000 deaths per year in developing countries. Early recognition and treatment are essential to managing PS, but numerous social, cultural and technical barriers prevent or delay access to care and necessary medical attention. Through this qualitative study, we identified barriers to care seeking for puerperal sepsis among recently delivered women in Matiari, Pakistan.
Methods: We conducted 20 in-depth interviews among recently delivered women with and without sepsis and their family members in September 2012. Key informant interviews were conducted with 14 healthcare providers and traditional …

Investigation Of Undocumented Heart Disease In Cadaveric Donors, Crystal Danae Passburg

Doctoral Dissertations and Projects

For nearly a century, heart disease has been the leading source of death and disease in the United States, causing the deaths of hundreds of thousands of individuals every year and burdening millions more with diminished health and severe disability. However, despite the significant known prevalence of heart disease, studies suggest that many more individuals—and particularly those within the female and elderly populations—may possess undiagnosed heart disease which remains undetected even after death due to the lack of autopsy examination. In the absence of autopsy, many cases of heart disease may never be identified, resulting in a skewed understanding of …

Sodium Butyrate Reduces Salmonella Enteritidis Infection Of Chicken Enterocytes And Expression Of Inflammatory Host Genes In Vitro, Anamika Gupta, Mohit Bansal, Basanta Raj Wagle, Xiaolun Sun, Narayan Rath, Annie Donoghue, Abhinav Upadhyay

Poultry Science Faculty Publications and Presentations

Salmonella Enteritidis (SE) is a facultative intracellular pathogen that colonizes the chicken gut leading to contamination of carcasses during processing. A reduction in intestinal colonization by SE could result in reduced carcass contamination thereby reducing the risk of illnesses in humans. Short chain fatty acids such as butyrate are microbial metabolites produced in the gut that exert various beneficial effects. However, its effect on SE colonization is not well known. The present study investigated the effect of sub-inhibitory concentrations (SICs) of sodium butyrate on the adhesion and invasion of SE in primary chicken enterocytes and chicken macrophages. In addition, the …

Covid-19, Lockdown, And The Dynamics Of Subjective Well-Being, Terence C. Cheng, Kim, Kanghyock Koh

Research Collection School Of Economics

We provide novel evidence on how the COVID-19 global health and economic crisis is affecting overall life satisfaction and domain-specific satisfaction using data from a monthly longitudinal survey of middle-aged and older Singaporeans. Using a difference-in-differences framework, we document large declines in overall life satisfaction and domain-specific satisfaction during the COVID-19 outbreak, except satisfaction with health. These declines coincide with the introduction of a nationwide lockdown, with life satisfaction remaining below its pre-pandemic levels even after the lockdown is lifted. We also find that individuals who report a drop in household income during the COVID-19 outbreak experience a decline in …

Spending Impact Of Covid-19 Stimulus Payments: Evidence From Card Transaction Data In South Korea, Kim, Kanghyock Koh, Wonjun Lyou

Research Collection School Of Economics

Various countries have implemented transfer programs to individuals since the Covid-19 outbreaks. However, the extent to which such transfers alleviate economic recessions is unclear. This paper analyzes a South Korean program, which provided vouchers redeemable only at small local businesses. We find that, due to the program, over 30% of households across all income groups increased their food and overall household spending, but the usage restriction may have affected consumer choice, distorting business competition. While the employment and sales of small businesses improved, the program’s fiscal sustainability is in question because of the large tax exemption.

The Ideals Of Law In A Health Crisis: Singapore’S Legislative Responses To Covid‐19, Benjamin Joshua Ong

Research Collection Yong Pung How School Of Law

Situations like the COVID-19 pandemic pose a dilemma. One might argue that such a crisis is a time for people to sacrifice their legal rights for the common good and submit to heavy restrictions on one’s liberties, surrendering individual liberties to a benevolent, though powerful, state. On the other hand, for every situation in history where an emergency has required people to accept such restrictions, there are many more situations in which an unscrupulous government has used a pretend emergency, or a real but exaggerated one, as an excuse to arrogate to himself sweeping arbitrary powers and refuse to let …

Understanding Characteristics Of The 100 Most Influential Studies On Covid-19 (Sars-Cov-2): A Bibliometric Analysis, Sidhartha Sahoo, Shriram Pandey, R. K. Mahapatra

Library Philosophy and Practice (e-journal)

Abstract

Background

In present study, we aimed to identify and evaluate the trends of the 100 most-cited research articles on Covid-19 using bibliometric techniques.

Methods

Scopus online database hosted by Elsevier was used to extract relevant articles for this study. We have identified the top 100 research papers on Covid-19 published across the globe based on their citations data. Further analysis was made to find the countries of origin, journal wise distribution, author cluster network, keyword analysis and inter-citation map to understand and to establish the links among them.

Results

The T100 most cited articles were published between January-August, 2020 …

An Intersectional Mixed Methods Approach To Understand American Indian Men’S Health, Ka‘Imi Sinclair, Kelly L. Gonzales, Claire Woosley, Tish Rivera Cree, Celina M. Garza, Dedra Buchwald

OHSU-PSU School of Public Health Faculty Publications and Presentations

This study used a parallel, convergent, mixed-methods design with TribalCrit theory and intersectionality as analytical frameworks to identify how the identities of American Indian men intersect with broader structures and systems in shaping their eating and physical activity choices and behaviors, and in eliciting recommendations for a men’s lifestyle intervention. American Indian men were recruited in Minneapolis, Minnesota, and Portland, Oregon, between March and December 2017, and in Phoenix, Arizona, in December 2019 to participate in a survey and focus groups. The survey included questions on demographics and physical and cultural activities men engage in, perceived social support for lifestyle …

Redesigning The Landscape For Women And Leadership: Insights Gained From The Covid-19 Pandemic. On Behalf Of Women In Gastroenterology Network Asia Pacific (Wignap) And Women In Endoscopy (Wie), Lubna Kamani, Nonthalee Pausawasdi, Jeanin E Van Hooft, Amrita Sethi, Sharmila Sachithanandan

Section of Gastroenterology

No abstract provided.

Letter: Thrombotic Neurovascular Disease In Covid-19 Patients., Ahmad Sweid, Batoul Hammoud, Joshua H. Weinberg, Mazen Oneissi, Eytan Raz, Maksim Shapiro, Maureen Deprince, Stavropoula Tjoumakaris, Michael R. Gooch, Nabeel A. Herial, Hekmat Zarzour, Victor Romo, Robert Rosenwasswer, Pascal Jabbour

Department of Neurosurgery Faculty Papers

Although the respiratory system is the primary target of the coronavirus, studies have demonstrated a strong tropism to the central nervous system (CNS).^1,2 The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects cells by binding to the angiotensin-converting enzyme 2 (ACE2) receptor. This receptor is also found in the CNS and plays a crucial role in autoregulating cerebral perfusion pressure.^3,4 Additionally, epidemiological data demonstrated increased mortality due to cardiovascular and cerebrovascular diseases during flu pandemics due to a hypercoagulable state.^5,6 The triad of neuroinvasion of SARS-CoV-2, induction of hypercoagulable state,^{5-9 …}