Digital Commons Network^™

Sepsis Smart Phrase To Improve Care: A Quality Improvement Project, Barbara Tlachac Webber, Cathleen Hoffman, Sara Bauer

Nursing

Background: Sepsis is a life-threatening infection with a mortality rate estimated between 25-50%. Majority of efforts to reduce mortality are focused on early identification and treatment. Many sepsis survivors experience cognitive impairment and functional disability that persist after discharge. Advocate Aurora Population Health Care Transitions Bundle Program telephonically coordinates care after discharge for 90 days with the intent to improve health outcomes measured by prevention of readmissions and ED utilization.

Local Problem:Care Transition readmission data was reviewed over a 3-month period in the spring of 2021, identifying sepsis as the initial diagnosis in 218 patients with a readmission rate …

Cauti Cnss Utilize A Tiger Team Approach To Decrease Hospital-Wide Cautis, Christine Wallis

Nursing

Background: Catheter associated urinary tract infections (CAUTIs) are the fifth most reported healthcare acquired infection (NHSN, 2022). Evidence has shown higher CAUTI rates are associated with increased patient length of stay, patient discomfort, and mortality. A meta-analysis yielded additional cost of a CAUTI to be estimated at $13,793 (AHRQ 2017). Hospital acquired infections have been shown to decrease with implementation of consistent evidenced based practices.

Local problem: Prevention of CAUTIs was identified as a high priority initiative on a journey to zero harm, in a 938-bed quaternary urban acute care hospital. The hospital wide CAUTI rate was 2.89 and the …

A Hands On Approach To Catheter Associated Urinary Tract Infections, Natalie Bell, Jessica Yates

Nursing

Background: Catheter-associated urinary tract infections (CAUTI) are the most prevalent hospital acquired condition across the United States. Evidence has highlighted effective CAUTI prevention strategies include reducing inappropriate short term catheter use, nurse driven timely removal of catheters, and catheter care during placement (American Nurses Association, n.d.).

Local problem: On a medical surgical unit with high volumes of post operative urology patients, the average utilization rate of urinary catheters is 1.27. And during quarter 2 2021 the CAUTI rates were 2.10.

Method: A unit specific quality improvement project to reduce CAUTIs was conducted utilizing an audit and re-education approach. To start …

Covid-19 Pandemic And Special Education Teacher Voices, Rama Cousik

The Qualitative Report

The pandemic caused by COVID-19 created havoc in schools across the world as it necessitated school closures and lockdowns, and/or a sudden switch to an online mode of learning. Although all children and teachers were adversely affected, children with disabilities faced additional problems. Special education teachers bore the burden of having to continue providing high quality special education in the face of these challenges. In this paper, I present findings from a survey of special education teachers through use of qualitative and arts-based research technics.

Sars-Cov-2 Incubation Period According To Vaccination Status During The Fifth Covid-19 Wave In A Tertiary-Care Center In Spain: A Cohort Study, Jordi Cortés Martínez, Daewoo Pak, Gabriela Abelenda-Alonso, Klaus Langohr, Jing Ning, Alexander Rombauts, Mireia Colom, Yu Shen, Guadalupe Gómez Melis

Faculty, Staff and Student Publications

Background: The incubation period of an infectious disease is defined as the elapsed time between the exposure to the pathogen and the onset of symptoms. Although both the mRNA-based and the adenoviral vector-based vaccines have shown to be effective, there have been raising concerns regarding possible decreases in vaccine effectiveness for new variants and variations in the incubation period.

Methods: We conducted a unicentric observational study at the Hospital Universitari de Bellvitge, Barcelona, using a structured telephone survey performed by trained interviewers to estimate the incubation period of the SARS-CoV-2 Delta variant in a cohort of Spanish hospitalized patients. The …

The Impact Of A New Stemi Hotline On Cardiovascular Outcomes In Stemi Patients Undergoing Primary Pci: A National Cohort Study, Fawaz Bardooli, Ali Alhashli, Omar Y. Alkhaja, Mohammed Faizal, Khaled Abdulmalek, Shaikha Musameh, Saad I. Mallah, Mohammed Alkhayat, Abdulkarim Abdulrahman

Journal of the Saudi Heart Association

Introduction: ST-Elevation myocardial infarction (STEMI) remains a common and challenging clinical condition with a high risk of mortality. STEMI complications are related directly to prolonged ischemia time. Mohamad Bin Khalifa Cardiac Centre (MKCC) established a national STEMI Hotline program on January 2022, to facilitate early detection and transfer of STEMI cases in the country to a dedicated tertiary cardiac center capable of performing primary PCI. Methods: This is an observational cohort study conducted on patients who presented to MKCC for primary PCI between August 2021 to February 2022. Patients who underwent primary PCI through referral from the newly developed STEMI …

It’S Your Turn, Are You Ready To Get Vaccinated? Towards An Exploration Of Vaccine Hesitancy Using Sentiment Analysis Of Instagram Posts, Mohammed Talha Alam, Shahab Saquib Sohail, Syed Ubaid, Shakil, Zafar Ali, Mohammad Hijji, Abdul Khader Jilani Saudagar, Khan Muhammad

Computer Vision Faculty Publications

The deadly threat caused by the rapid spread of COVID-19 has been restricted by virtue of vaccines. However, there is misinformation regarding the certainty and positives outcome of getting vaccinated; hence, many people are reluctant to opt for it. Therefore, in this paper, we identified public sentiments and hesitancy toward the COVID-19 vaccines based on Instagram posts as part of intelligent surveillance. We first retrieved more than 10k publicly available comments and captions posted under different vaccine hashtags (namely, covaxin, covishield, and sputnik). Next, we translated the extracted comments into a common language (English), followed by the calculation of the …

10 Appointed To Endowed Positions, Linda Gunter

Browse All News

No abstract provided.

Covid-19 Newsletter (Vol. 144), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Cardiac Myosin-Specific Autoimmune T Cells Contribute To Immune-Checkpoint-Inhibitor-Associated Myocarditis, Johns Hopkins University School Of Medicine, Johns Hopkins University Bloomberg School Of Public Health, Johns Hopkins University Whiting School Of Engineering, Ninaad Lasrado, Jay Reddy, Daniela Ciháková

School of Veterinary and Biomedical Sciences: Faculty Publications

Immune checkpoint inhibitors (ICIs) are an effective therapy for various cancers; however, they can induce immune-related adverse events (irAEs) as a side effect. Myocarditis is an uncommon, but fatal, irAE caused after ICI treatments. Currently, the mechanism of ICI-associated myocarditis is unclear. Here, we show the development of myocarditis in A/J mice induced by anti-PD-1 monoclonal antibody (mAb) administration alone without tumor cell inoculation, immunization, or viral infection. Mice with myocarditis have increased cardiac infiltration, elevated cardiac troponin levels, and arrhythmia. Anti-PD-1 mAb treatment also causes irAEs in other organs. Autoimmune T cells recognizing cardiac myosin are activated and increased …

Cardiac Myosin-Specific Autoimmune T Cells Contribute To Immune-Checkpoint-Inhibitor-Associated Myocarditis, Taejoon Won, Hannah M. Kalinoski, Megan K. Wood, David M. Hughes, Camille M. Jaime, Paul Delgado, Monica V. Talor, Ninaad Lasrado, Jay Reddy, Daniela Čiháková

Jay Reddy Publications

Immune checkpoint inhibitors (ICIs) are an effective therapy for various cancers; however, they can induce immune-related adverse events (irAEs) as a side effect. Myocarditis is an uncommon, but fatal, irAE caused after ICI treatments. Currently, the mechanism of ICI-associated myocarditis is unclear. Here, we show the development of myocarditis in A/J mice induced by anti-PD-1 monoclonal antibody (mAb) administration alone without tumor cell inoculation, immunization, or viral infection. Mice with myocarditis have increased cardiac infiltration, elevated cardiac troponin levels, and arrhythmia. Anti-PD-1 mAb treatment also causes irAEs in other organs. Autoimmune T cells recognizing cardiac myosin are activated and increased …

A High-Resolution 3d Atlas Of The Spectrum Of Tuberculous Andcovid-19 Lung Lesions, Gordon Wells, Joel N Glasgow, Kievershen Nargan, Kapongo Lumamba, Rajhmun Madansein, Kameel Maharaj, Leon Y Perumal, Malcolm Matthew, Robert L Hunter, Hayden Pacl, Jacelyn E Peabody Lever, Denise D Stanford, Satinder P Singh, Prachi Bajpai, Upender Manne, Paul V Benson, Steven M Rowe, Stephan Le Roux, Alex Sigal, Muofhe Tshibalanganda, Carlyn Wells, Anton Du Plessis, Mpumelelo Msimang, Threnesan Naidoo, Adrie J C Steyn

Faculty, Staff and Student Publications

Our current understanding of the spectrum of TB and COVID-19 lesions in the human lung is limited by a reliance on low-resolution imaging platforms that cannot provide accurate 3D representations of lesion types within the context of the whole lung. To characterize TB and COVID-19 lesions in 3D, we applied micro/nanocomputed tomography to surgically resected, postmortem, and paraffin-embedded human lung tissue. We define a spectrum of TB pathologies, including cavitary lesions, calcium deposits outside and inside necrotic granulomas and mycetomas, and vascular rearrangement. We identified an unusual spatial arrangement of vasculature within an entire COVID-19 lobe, and 3D segmentation of …

Community In The Colorado River Basin, Jason Robison, Matthew Mckinney, Daryl Vigil

Idaho Law Review

No abstract provided.

Finding Aid For The Bobby Moak Collection (Mum00756)

Archives & Special Collections: Finding Aids (alphabetical)

A Democrat, Bobby Moak represented District 93 and District 53 in the Mississippi House of Representatives from 1984 to 2016. He chaired the Investigate State Offices Committee in 2000-2003 and the Gaming Committee from 2004 to 2011. Moak served as Democratic Minority Leader from 2012 to 2016.

Impact Of Mask Wearing On Post-Exercise Hemodynamics, Payton J. Price, Zachary Zeigler, Luke Heikka, Adarius West, Sofia Harman, Anthony Acevedo

International Journal of Exercise Science: Conference Proceedings

As the guidelines regarding COVID-19 regressed, many fitness centers established regulations requiring mask-wearing during exercise. Data suggest that the impact of a mask during exercise has minimal effects on exercise hemodynamics. The post-exercise period has been described as a window of opportunity to lower blood pressure, a phenomenon called post-exercise hypotension. The impact of wearing a mask on post-exercise hemodynamics is unknown. PURPOSE: The purpose of this study was to examine the impact of mask-wearing during exercise on post-exercise hemodynamics. METHODS: Nine total participants aged 18-30 yr were recruited for this experimental cross-over study. This within-subject design involved …

The Relationship Among Maternal Characteristics, Maternal Dietary Self-Regulation, And The Dietary Intake And Body Weight Status Of Two To Five-Year-Old Children, Andrea Bushaw

Dissertations

Eating preferences and practices are established early in life, yet we have little knowledge about how mothers make food decisions on behalf of their children. These decisions, however, lay the foundation for their child's lifelong food preferences and eating behaviors. Almost one-third of all children in the U.S. are overweight or obese putting them at high risk for becoming an overweight or obese adult. To make a difference in the ongoing obesity epidemic, we must better understand the relationship among characteristics of the mother who controls the young child's access to food, food choices, and feeding practices. This knowledge will …

The “Big Six”: Hidden Emerging Foodborne Bacterial Pathogens, Mona G. Alharbi, Rashad R. Al-Hindi, Ahmed Esmael, Ibrahim A. Alotibi, Sheren A. Azhari, Mazen S. Alseghayer, Addisu D. Teklemariam

Nebraska Center for Virology: Faculty Publications

Non-O157 Shiga toxin-producing Escherichia coli (STEC) are emerging serogroups that often result in diseases ranging from diarrhea to severe hemorrhagic colitis in humans. The most common non-O157 STEC are O26, O45, O103, O111, O121, and O145. These serogroups are known by the name “big six” because they cause severe illness and death in humans and the United States Department of Agriculture declared these serogroups as food contaminants. The lack of fast and efficient diagnostic methods exacerbates the public impact of the disease caused by these serogroups. Numerous outbreaks have been reported globally and most of these outbreaks were caused by …

Understanding The Mental Health Impact And Needs Of Public Healthcare Professionals During Covid-19 In Pakistan : A Qualitative Study, Waqas Hameed, Anam Shahil Feroz, Bilal Iqbal Avan, Bushra Khan, Zafar Fatmi, Noreen Afzal, Hussain Jafri, Mansoor Ali Wassan, Sameen Siddiqi

Community Health Sciences

Objectives: A dearth of qualitative studies constrains in-depth understanding of health service providers' perspectives and experiences regarding the impact of COVID-19 on their mental health. This study explored the mental health impact and needs of of public sector healthcare workers during COVID-19 who working in secondary-level and tertiary-level healthcare settings of Pakistan.
Design: An exploratory qualitative study.
Setting: Twenty-five secondary-level and eight tertiary-level public hospitals of Sindh and Punjab provinces of Pakistan.
Participants: In-depth interviews were conducted with 16 health service providers and 40 administrative personnel. Study data were analysed on NVivo V.11 using the conventional content analysis technique.
Results: …

Sex-Biased Differences In Infant Mortality And Life Expectancy At At Síi Túupentak, An Ancestral Ohlone Village In Central California (Ca. 540–145 Cal. Bp), Tammy Buonasera, Jelmer Eerkens, Brian Byrd, Laurel Engbring, Monica Arellano, Alan Leventhal, Glendon Parker

Human Biology Open Access Pre-Prints

Síi Túupentak (CA-SCA-565/H) is a late precontact ancestral Ohlone village and cemetery site in central California (ca. 540-145 cal. BP). Integration of proteomic, genomic, and osteological analyses provided highly confident biological sex estimates for remains of most individuals at this site (65 of 76) spanning all age groups—from perinatal infants to aged adults. The comprehensive nature of the data allowed us to generate sex-specific Kaplan-Meyer survivorship curves for this burial population of sedentary hunter-gatherers. As was common among societies pre-dating modern western medicine and antibiotics, infant mortality was high for both males and females. However, male infants (from birth to …

A Novel Vaccine Candidate Against Rabbit Hemorrhagic Disease Virus 2 (Rhdv2) Confers Protection In Domestic Rabbits, Angela M. Bosco-Lauth, Bethany Cominsky, Stephanie Porter, J. Jeffrey Root, Amber Schueler, Gary Anderson, Sara Vanderwal, Andy Benson

United States Department of Agriculture Wildlife Services: Staff Publications

OBJECTIVE To evaluate efficacy of a novel vaccine against rabbit hemorrhagic disease virus 2 (RHDV2) in domestic rabbits.

ANIMALS 40 New Zealand White rabbits obtained from a commercial breeder.

PROCEDURES Rabbits were vaccinated and held at the production facility for the duration of the vaccination phase and transferred to Colorado State University for challenge with RHDV2. Rabbits were challenged with oral suspensions containing infectious virus and monitored for clinical disease for up to 10 days. Rabbits that died or were euthanized following infection were necropsied, and livers were evaluated for viral RNA via RT-PCR.

RESULTS None of the vaccinated animals …

Uab Ranked In Top 8 Percent Of Global Universities By U.S. News, Alicia Rohan

Browse All News

No abstract provided.

Interpretable Deep Learning For Discriminating Pneumonia From Lung Ultrasounds, Mohamed Abdel-Basset, Hossam Hawash, Khalid Abdulaziz Alnowibet, Ali Wagdy Mohamed

Faculty Journal Articles

Lung ultrasound images have shown great promise to be an operative point-of-care test for the diagnosis of COVID-19 because of the ease of procedure with negligible individual protection equipment, together with relaxed disinfection. Deep learning (DL) is a robust tool for modeling infection patterns from medical images; however, the existing COVID-19 detection models are complex and thereby are hard to deploy in frequently used mobile platforms in point-of-care testing. Moreover, most of the COVID-19 detection models in the existing literature on DL are implemented as a black box, hence, they are hard to be interpreted or trusted by the healthcare …

The Stockholm Paradigm: Lessons For The Emerging Infectious Disease Crisis, Daniel R. Brooks, Walter A. Boeger, Eric P. Hoberg

MANTER: Journal of Parasite Biodiversity

The emerging infectious disease (EID) crisis represents an immediate existential threat to modern humanity. Current policies aimed at coping with the EID crisis are ineffective and unsustainably expensive. They have failed because they are based on a scientific paradigm that produced the parasite paradox. The Stockholm paradigm (SP) resolves the paradox by integrating four elements of evolutionary biology: ecological fitting, sloppy fitness space, coevolution, and responses to environmental perturbations. It explains why and how the EID crisis occurs and is expanding and what happens after an EID emerges that sets the stage for future EIDs. The SP provides a number …

The Dama Protocol, An Introduction: Finding Pathogens Before They Find Us, Eric P. Hoberg, Walter A. Boeger, Orsolya Molnár, Gábor Földvári, Scott L. Gardner, Alicia Juarrero, Vitaliy A. Kharchenko, Eloy Ortiz, Wolfgang Preiser, Valeria Trivellone, Daniel R. Brooks

MANTER: Journal of Parasite Biodiversity

Globally, humanity is coming to recognize the magnitude of the interactive crisis for emerging infectious disease (EID). Strategies for coping with EID have been largely in the form of reactive measures for crisis response. The DAMA protocol (Document, Assess, Monitor, Act), the operational policy extension of the Stockholm paradigm, constitutes a preventive/proactive dimension to those efforts. DAMA is aimed at focusing and extending human and material resources devoted to coping with the accelerating wave of EID. DAMA is integrative, combining efforts to strategically document the distribution of complex pathogen and host assemblages in the biosphere in the context of dynamic …

Cladophialophora Bantiana Brain Abscess And Concurrent Pulmonary Cryptococcus Neoformans Infection In A Patient Twenty Years After Renal Transplantation, Daniel Tsang, Sara Haddad, Ziver Sahin, Chairut Vareechon, Mitchell Sternlieb, Tricia. Royer

Department of Medicine Faculty Papers

Recipients of solid organ transplants are at risk for a variety of infections due to their immunocompromised status. The types of infections are often correlated to the timing from their transplant. After about six to twelve months, transplant recipients remain at risk for typical community acquired pathogens, late viral infections, and fungal infections including atypical molds such as Cladophialophora bantiana. C. bantiana is a dematiaceous fungus that has a predilection for infecting the brain and is the most common cause of cerebral phaeohyphomycosis - a term used to describe infections caused by molds that produce dark cell walls. Patients with …

Acute Hypersensitivity Reaction After Casirivimab/Imdevimab Infusion In A Covid-19-Positive Young Male: Myopericarditis Or Kounis Syndrome?, Jose A. Rivera, Daniel Aragon, Jose Gomez, Hector Arredondo, Paul Dominici, Olabiyi O. Akala, Michael Menowsky

School of Medicine Publications

Myocarditis has been a rare, but well-documented side effect of the mRNA-based vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as well as a complication of viral infections including SARS-CoV-2. However, myopericarditis as a complication of monoclonal antibody infusion or as a complication of allergic reaction to antibody infusions might be underreported.

We report the case of a 30-year-old man with a previous diagnosis of coronavirus disease 2019 (COVID-19) infection one week prior to presentation, unvaccinated for SARS-CoV-2, who was referred from a monoclonal infusion center where he received casirivimab/imdevimab and 15 minutes after the infusion began to complain …

Resilience Resources And Coping Strategies Of Covid-19 Female Long Haulers: A Qualitative Study, Atefeh Aghaei, Abhishek Aggarwal, Ran Zhang, Xiaoming Li Ph.D., Shan Qiao Ph.D.

Faculty Publications

Background: Female long haulers deal with persistent post-acute COVID-19 symptoms that have serious health implications. This study aimed to identify resilience resources at multiple socio-ecological levels for female long haulers and describe how resilience resources affect their responses to long COVID. Methods: Purposive sampling was adopted to recruit participants through social media from April to June 2021 followed by 15 semi-structured interviews. An inductive analytical approach was adopted to categorize themes by open and axial coding that were verified by peer review. Results: Female long haulers relied on resources at various socio-ecological levels to foster their resilience in response to …

November 4, 2022 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

‘Long Social Distancing’ Reduces Potential Output Of U.S. Economy, Jose Maria Barrero

Upjohn Institute Policy and Research Briefs

No abstract provided.

Long Social Distancing, Jose Maria Barrero, Nicholas Bloom, Steven J. Davis

Upjohn Institute Working Papers

Many working-age Americans say they will continue some forms of social distancing after the COVID-19 pandemic ends. We uncover this long social distancing phenomenon in our monthly Survey of Working Arrangements and Attitudes. It is stronger among older persons, the less educated, and those who live with or care for persons at high risk from infectious diseases. Regression models fit to individual-level data suggest that social distancing lowered labor force participation by 2.4 percentage points in 2022, 1.2 points on an earnings-weighted basis. Daily interactions with at-risk persons and long COVID experiences lead to larger drags on participation. When combined …