Digital Commons Network^™

Interview With Valerie Crowley, Utah State University Special Collections & Archives

Utah State University COVID-19 Oral History Collection

No abstract provided.

Characterizing The Cutaneous Microbiome Of Eurycea Lucifuga As A Potential Defense Against Chytridiomycosis, Madeline Key

Senior Honors Theses

Chytridiomycosis is an emerging infectious disease that is significantly reducing global amphibian populations. The disease is caused by Batrachochytrium dendrobatidis (Bd), a fungus that lethally modifies amphibian skin. Recent research has suggested that the cutaneous microbiome of individual amphibians may play a role in susceptibility to the pathogen. In this study, twelve cave salamanders (Eurycea lucifuga) were collected. Cutaneous bacteria from each salamander were isolated and identified using Sanger Sequencing. Additionally, a Bd-challenge assay was performed to determine each isolate’s antifungal activity. Results indicated many microbial isolates possessed inhibitory capabilities against Bd, which may …

Increasing The Prescribing Of Pre-Exposure Prophylaxis (Prep) With A Pre-Exposure Prophylaxis Screening Tool, Cassey Hall

Student Scholarly Projects

Practice Problem: Human Immunodeficiency Virus (HIV) is one of the leading pandemics in the world. In 2019, 38 million people were living with HIV around the world. Of those, roughly 87% were aware of their HIV status.

PICOT: In patients with high risk for HIV, how does implementing a pre-exposure (PrEP) screening tool compared to randomly screening for pre-exposure prophylaxis (PrEP) affect the prescribing of pre-exposure prophylaxis (PrEP) within eight weeks?

Evidence: In 2015, the World Health Organization (WHO) recommended PrEP for the prevention of HIV in high-risk individuals. The patients include men who have sex with …

Social Networks, High-Risk Anal Hpv And Coinfection With Hiv In Young Sexual Minority Men, Kayo Fujimoto, Alan G Nyitray, Jacky Kuo, Jing Zhao, Lu-Yu Hwang, Elizabeth Chiao, Anna R Giuliano, John A Schneider, Aditya Khanna

Faculty, Staff and Student Publications

OBJECTIVES: Young sexual minority men (SMM) exhibit a high prevalence and incidence of high-risk genotypes of human papillomavirus (hrHPV) anal infections and a confluence of a high prevalence of HIV and rectal STIs. Social determinants of health (SDOHs) are linked to social network contexts that generate and maintain racial disparities in HIV and STIs. A network perspective was provided to advance our knowledge of drivers of genotype-specific hrHPV infection and coinfection with HIV. The study also examined whether socially connected men are infected with the same high-risk HPV genotypes and, if so, whether this tendency is conditioned on coinfection with …

Beyond The Unknown: A Broad Framing For Preparedness For Emerging Infectious Threats, Rebecca C. Christofferson, Stephania A. Cormier

Division of Basic Science Faculty Publications

There have been multiple instances of novel pathogen emergence that have affected the health and security of the global community. To highlight that these novel pathogens presented a clear danger to public health, the WHO included “Disease X” on their list of priority pathogens in 2018. Indeed, since the emergence of SARS-CoV-2, Disease X has been pointed to as the looming threat of “the next big thing.” However, developing surveillance and preparedness plans with Disease X as the linchpin is too narrow and ignores a large swath of potential threats from already identified, often neglected diseases. We propose instead the …

Probiotic Incorporation Into Yogurt And Various Novel Yogurt-Based Products, Douglas W. Olson, Kayanush J. Aryana

Faculty Publications

Probiotics are commonly added to yogurt to provide many health benefits for the consumer. A description is provided for some commonly used probiotics in yogurt. A GRAS (generally recognized as safe) list of probiotic bacteria that can be added to yogurt or similar types of products is provided. Additionally, prebiotics, synbiotics (combination of prebiotics and probiotics), postbiotics, paraprobiotics, and psychobiotics can be added to yogurt. Probiotic yogurt can come in various forms in addition to spoonable yogurt, and yogurt can be used as an ingredient in other food products. Many useful functional ingredients can be applied to probiotic yogurt. The …

Inspire : Vol 5, Issue 12, Department Of Medicine

INSPIRE – Department of Medicine Archives

• Message from the Chair
• 7^th WOHC Singapore
• World Stroke Day
• PZP Hospitalist Grand Round
• PADCON
• PZP Hospitalist Grand Round
• International Kidney Transplant Symposium
• UPDATES ON COPD
• In-depth- featuring Assistant Prof. Dr Mehreen Arshad
• What are Academics Around the World Reading This Month?
• Publications

Prophylactic Profit: The One-Sided Compromise, Arash Aalem

University of the Pacific Law Review

No abstract provided.

Epidemic Time Series Similarity Is Related To Geographic Distance And Age Structure, Tad Dallas, Grant Foster, Robert L. Richards, Bret D. Elderd

Faculty Publications

Objective

More similar locations may have similar infectious disease dynamics. There is clear overlap in putative causes for epidemic similarity, such as geographic distance, age structure, and population size. We compare the effects of these potential drivers on epidemic similarity compared to a baseline assumption that differences in the basic reproductive number (R₀) will translate to differences in epidemic trajectories.

Methods

Using COVID-19 case counts from United States counties, we explore the importance of geographic distance, population size differences, and age structure dissimilarity on resulting epidemic similarity.

Results

We find clear effects of geographic space, age structure, …

Global Adverse Effects Of Scientific Prescribed Medications: Covid-19 Vaccines, Albert Mcbell Ninepence

Young African Leaders Journal of Development

The impact of scientific prescribed medications are tremendous and cannot be overemphasized. Irrespective of scientific prescribed medications impacts, in recent epoch it has attracted some criticisms on its efficacy. Prescribed medications are medications from scientific treatments or cure which is the widely accepted approach to curing or treating illnesses and diseases. On the other hand, traditional prescribed medications which are non-scientific tend to be less utilized, ignored and extremely criticized by pure scientists. The criticisms surrounding scientific prescribed medications escalated during the era of COVID-19. While some people resorted to the use of scientific prescribed medications of COVID-19 vaccines to …

Metabolic Alterations And Cardiovascular Risk After Hepatitis C Cure In Subjects With Or At Risk For Hiv, Christophe Maxime Fokoua Dongmo

Legacy Theses & Dissertations (2009 - 2024)

Background. Hepatitis C virus (HCV) infection engenders substantial metabolic changes. These changes are altered when the virus is cleared after successful treatment. We measured these metabolic alterations that occur after HCV cure; further, we assessed whether these alterations differed in subgroups defined by patients’ characteristics.

Should Maine Develop A More Comprehensive Approach To Invasive Species Management, Gary Fish

Muskie School Capstones and Dissertations

Currently the state of invasive species management in Maine seems to be very siloed with little interagency or organizational coordination or prioritization. To assess the current situation, a survey was created and sent to approximately 600 recipients (Appendix 1). Recipients included representatives from state, federal, non-profit and private organizations that are known actors in the invasive species community in Maine. The survey was also posted on the Maine Invasive Species Network listserv.12 There were 197 respondents which provides a significant but incomplete sample of the management efforts currently taking place in Maine. Respondents represented all potential affiliations involved in invasive …

Covid-Associated Non-Vasculitic Thrombotic Retiform Purpura Of The Face And Extremities: A Case Report, Connor M. Bunch, Nuha Zackariya, Anthony V. Thomas, Jack H. Langford, Michael Aboukhaled, Samuel J. Thomas, Aida Ansari, Shivani S. Patel, Hallie Buckner, Joseph B. Miller Md, Christy L. Annis, Margaret A. Quate-Operacz, Leslie A. Schmitz, Joseph J. Pulvirenti, Jonathan C. Konopinski, Kathleen M. Kelley, Samer Hassna, Luke G. Nelligan, Mark M. Walsh

Emergency Medicine Articles

SARS-CoV-2 infection can manifest many rashes. However, thrombotic retiform purpura rarely occurs during COVID-19 illness. Aggressive anti-COVID-19 therapy with a high-dose steroid regimen led to rapid recovery. This immunothrombotic phenomenon likely represents a poor type 1 interferon response and complement activation on the endothelial surface in response to acute infection.

Developing The Who's Pandemic Treaty To Facilitate Global Solidarity And International Accountability, Sonam K. Shah

North Carolina Law Review

No abstract provided.

A Comparison Of The Treatments Of Al-Razi To Those Of His Contemporary Physicians And To Modern Medicine, Nicholas E. Brough

Honors Projects

Introduction: The Golden Age of the Islamic Empire was a time of great scientific advancements. Due to the support of the Abbasid Caliphate, centers of learning such as the Baghdad House of Wisdom produced translations of Greek medical texts which formed the basis of medicine in Medieval Islam. This led the Islamic Empire to produce some of the greatest physicians of all time including al-Razi. Analysis: The treatments used by al-Razi in his thirty-three case studies from al-Hawi are all theoretically effective through the lens of humoral medicine. Additionally, many of al-Razi’s treatments are backed by research into the phytochemical …

Creating Nutrition Education For Lactating Parents, Audrey Fohey

Honors Capstones

Lactation is an important life stage that requires a unique emphasis on nutritional intake; existing educational materials on this topic do a poor job of meeting the needs of lactating parents. The purpose of this project was to work with a community partner, the DeKalb County WIC, to create educational materials that will address this issue. The creation of the educational materials was a multi-step process, involving exploration of the relationship between nutrition and lactation and collaboration with the established community partner. A written paper was synthesized, and three handouts were created. Each handout focused on a specific nutrient of …

Good Faith: Surveillance And Evaluation Of 911 Good Samaritan Laws In The United States, Shane W. Reader

Dissertations and Theses (Open Access)

To fight soaring overdose mortality rates in the United States, lawmakers adopted a variety of harm reduction tools. Among these, 911 Good Samaritan Laws (GSLs) derive their name from the biblical parable of the Good Samaritan, a bystander who broke cultural convention to come to the aid of a man beset by thieves. These laws provide limited criminal immunity for bystanders in possession of controlled substances to encourage them to report drug overdoses. While previous studies associate GSLs with a modest reduction in opioid mortality, analyses often model them as equivocal or divide them coarsely across individual provisions. Evaluating these …

What Is Contributing To Covid-19 Mortality In Harris County, Texas?, Rachel Roy

Dissertations and Theses (Open Access)

The COVID-19 pandemic exposed long-standing inequities that have been present in the United States since its origin. While the entire country has been devastated by this pandemic, low-income and minority communities were hardest hit. Race alone does not predict poor health outcomes. Rather, the historic strategies implemented in the United States, such as redlining, placed racial and ethnic minorities in neighborhoods where cycles of disinvestment in education, transportation infrastructure, flooding infrastructure, healthy food, and clean air and water have created low socioeconomic status and poor health outcomes. This public health research aims to understand how historical processes have created and …

Seroprevalence And Titer Concentration Testing For Leptospirosis In Equine, Ashley Himmelsbaugh

Honors College Theses

The most common best management practice used to combat diseases in horses is vaccination, which can decrease the incidence or severity of illness. However, the duration of immunity will vary for each vaccination and must be considered for revaccination purposes. Titer concentration, which evaluates antibodies in the blood, may be a helpful way of determining how long an animal has immunity to a disease. Leptospirosis, a zoonotic, bacterial disease, can result in uveitis, potentially leading to blindness, and abortion in mares. One serovar, Leptospirosis pomona (L. pomona), is associated with most cases of clinical disease in horses in North America. …

Use Of The Nursing Practice Grade As A Predictor Of Registered Nurse Examination First Attempt Pass Rate Of Baccalaureate Nursing Graduates, Shu-Ying Fu, Jen-Hung Wang, Jiin-Ling Jiang

Journal of Medical Education

Purpose: This study aimed to examine whether the nursing practice grade can serve as a predictor of pass rate for the first attempt of the Registered Nurse (RN) Examination of baccalaureate nursing graduates. Methods: A retrospective study was conducted to collect data from the Nursing Practice Management System in one university. Data covered the grades of various nursing practice courses of students who graduated from 2015 to 2019. All the students had completed the required nine nursing practice courses. The outcome was pass/ fail in the first attempt of the RN examination. Results: Among a total of 260 students, most …

Exploring Stress In Adolescents Regarding The Covid-19 School Closure, Anna Beck

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Background: The purpose of this literature review, is to explore the stress adolescents faced during the times of the COVID-19 pandemic. This includes the rates of stress, other psychological consequences, such as depression and anxiety, as well as factors that could have contributed to the development of stress and those that could have helped relieve feelings of distraught.

Purpose: To create a more holistic approach in nursing care, finding reasonings behind the creation of stress in the young population, as well as methods to alleviate, can help patient satisfaction and support.

Method: A literature review was conducted over 20 peer …

The East Africa Consortium For Human Papillomavirus And Cervical Cancer In Women Living With Hiv/Aids, Y. Tong, Elkanah Omenge, M. Nakalembe, P. Tonui, P. Itsura, K. Muthoka, M. Titus, S. Kiptoo, A. Mwangi, J. Ong’Echae

Obstetrics and Gynaecology, East Africa

The East Africa Consortium was formed to study the epidemiology of human papillomavirus (HPV) infections and cervical cancer and the influence of human immunodeficiency virus (HIV) infection on HPV and cervical cancer, and to encourage collaborations between researchers in North America and East African countries. To date, studies have led to a better understanding of the influence of HIV infection on the detection and persistence of oncogenic HPV, the effects of dietary aflatoxin on the persistence of HPV, the benefits of antiretroviral therapy on HPV persistence, and the differences in HPV detections among HIV-infected and HIV-uninfected women undergoing treatment for …

Snapshot Of Rsv, Urvashi Mathur, Barbara Stewart

MEDI 9331 Scholarly Activities Clinical Years

Background: Respiratory syncytial virus (RSV) is known to cause bronchiolitis and other upper respiratory infections (URIs) in children. However, given the COVID-19 pandemic and the resultant lockdowns, circulation of other respiratory viruses was uncharacteristically low. Restrictions are quickly falling and with increased interaction there has been an uncharacteristic jump in cases.

Purpose: To summarize the pathogenesis of RSV and the mechanisms the virus uses to evade immune responses. Additional discussion of the increased rates of RSV hospitalizations as well as the role of vaccinations in controlling infection.

An Integrated Electronic-Skin Patch For Real-Time And Continuous Monitoring Of A Panel Of Biomarkers Combined With Drug Delivery, Tanzila Noushin

Electrical Engineering Theses

Inflammatory biomarkers present in the human body play a vital role in medical field by guiding the clinician in decision-making for many diseases. The levels of these inflammatory biomarkers are associated with the severity and progress of several diseases. Researchers have found that increasing severity of many diseases such as cardiovascular disease, after surgery infection, and adverse clinical outcomes due to infectious diseases, results in the elevation of the level of inflammatory biomarkers in human sweat. Furthermore, the inflammatory cytokines indicate the pathophysiology and prognosis of critically ill SARS‑CoV‑2 patients. In this thesis work, different sensors have been developed for …

Hospital-Acquired Malnutrition In The Pediatric Population: A Cross-Sectional Study, Annida Falahaini, Dessie Wanda

Jurnal Keperawatan Indonesia

Malnutrition is a global problem, from which hospitalized patients are not exempt. Hospital-acquired malnutrition (HaM) is associated with adverse outcomes in pediatric patients. Therefore, health professionals need to understand the factors related to the issue in such patients. This study aims to identify the factors associated with the prevalence of HaM in pediatric patients. It employed a cross-sectional design involving children from one month to 18 years old who had been hospitalized for at least 72 hours. HaM was determined by a weight loss of more than 2% by the fourth day of hospitalization. The final sample was 373, from …

Dean's Update, December 2022, Jerry L. Nadler

SOM Dean's Research Newsletter

No abstract provided.

Changes In Streptococcus Pneumoniae Susceptibility In Wisconsin: Implications For Clinical Treatment Decisions For Respiratory Infections, Erik Munson, Stephen C. Lavey, Megan R. Lasure, Barry C. Fox

Clinical Lab Sciences Faculty Research and Publications

Objective: In 2019, the American Thoracic Society and Infectious Diseases Society of America updated clinical practice guidelines for community-acquired pneumonia (CAP). In contrast to guidelines published in 2007, macrolide monotherapy for outpatients was made a conditional recommendation based on resistance levels. Local knowledge of current antimicrobial susceptibility is needed to guide management of CAP and other bacterial respiratory pathogens. The purpose of this study was to investigate antimicrobial susceptibility profiles and trending for Wisconsin Streptococcus pneumoniae isolates.

Design: Multi-center laboratory surveillance, with testing at a central location utilizing standardized susceptibility testing protocols.

Methods: Data published by the Wisconsin Department of …

Experiences Of Mothers And Significant Others In Accessing Comprehensive Healthcare In The First 1000 Days Of Life Post-Conception During Covid-19 In Rural Uganda, Grace Nakate, Sean Mackay, Eunice Ndirangu, Valerie Fleming

School of Nursing & Midwifery, East Africa

Background: COVID-19 presented an unprecedented global public health challenge because of its rapid and relentless spread, and many countries instituted lockdowns to prevent the spread of infection. Although this strategy mayhave been appropriate to reduce infection, it presented unintended difficulties in rural Uganda, especially in maternal and born newborn care. For example, some services were suspended, meaning the nearest health facility was at a considerable distance. This study explored the experiences of mothers and their significant others of comprehensive care in the first 1000 days of life post-conception during the COVID-19 pandemic in Bunghokho-Mutoto sub-county, Mbale District, Uganda.

Methods …

Exploring The Effects Of Fatty Acids (Pufas) On The Antimicrobial Resistance In Vibrio Cholerae, Naina Patel

Honors Theses

As antibiotic resistance becomes a major challenge for public health professionals, our research objectives aimed to investigate the potential for polyunsaturated fatty acids (PUFAs) to create membrane vulnerability in the gram-negative pathogen Vibrio cholerae to help improve the efficacy of several antibiotics. V. cholerae, normally residing in aquatic environments, is capable of altering its phospholipid composition through the uptake and assimilation of exogenous polyunsaturated fatty acids. The purpose of this study was to measure PUFA-mediated changes in the membrane permeability and antibiotic resistance of Vibrio cholerae. The three physiologically relevant PUFAs used were linoleic acid [18:2], arachidonic acid [20:4], and …

The Effect Of Volatile Organic Compounds On Endothelial Function And Atherogenesis., Samantha Mcfall

Electronic Theses and Dissertations

Volatile organic compounds (VOCs) are a group of pervasive air pollutants that are released into the atmosphere from both anthropogenic and environmental sources. Recent epidemiological studies suggest that exposure to various VOCs is associated with an increased risk of cardiovascular disease. However, the relationship between VOCs and cardiovascular disease is not well-studied. Using animal models and three select VOCs, benzene, xylene, and trichloroethylene, we studied the effects of VOCs on endothelial injury and benzene-induced atherogenesis. We found that exposure to benzene and xylene increased circulating endothelial microparticles, depleted progenitor cells, and increased platelet activation. Following the exposure to the representative …