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Rare Predicted Loss-Of-Function Variants Of Type I Ifn Immunity Genes Are Associated With Life-Threatening Covid-19, Daniela Matuozzo, Megan A. Cooper, Et Al. Jan 2023

Rare Predicted Loss-Of-Function Variants Of Type I Ifn Immunity Genes Are Associated With Life-Threatening Covid-19, Daniela Matuozzo, Megan A. Cooper, Et Al.

2020-Current year OA Pubs

No abstract provided.

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Doctoral Students’ Experiences Of The Pandemic And Their Perceptions Of Grit, Josie Bryant Jan 2023

Doctoral Students’ Experiences Of The Pandemic And Their Perceptions Of Grit, Josie Bryant

Murray State Theses and Dissertations

The pandemic has significantly changed societal structures and individuals’ lives. The early tragedies and stress of the pandemic affected health, relationships, families, education, work, travel, and immigration. Students who entered doctoral programs in 2020 chose a unique time to pursue an already arduous goal amidst unprecedented challenges. Using a phenomenological approach, this study explored doctoral students’ experiences during the pandemic and sought to understand their perspectives of grit. The study aimed to offer first-hand insight into the pandemic’s effects on doctoral students, and add critical contributions to understanding the necessary actions, support systems, and policies for a life in a …

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3d Printed Microfluidic Devices For Advanced Fluid Manipulation In Biomedical Applications, Kathrine Curtin Jan 2023

3d Printed Microfluidic Devices For Advanced Fluid Manipulation In Biomedical Applications, Kathrine Curtin

Graduate Theses, Dissertations, and Problem Reports (ETD)

Microfluidics are valuable devices in the biomedical field because of their remarkable ability to manipulate small volumes of fluid and facilitate reactions. Microfluidics have several significant advantages, including their portability, low cost, fast reaction times, and high surface area-to-volume ratios. Microfluidics be used for a multitude of applications, including bioanalysis, cellular assays, organ-on-a-chip, and separations. Microfluidics have great potential to overcome many challenges in conventional chemical and biological applications. However, complex fabrication procedures in silicon, glass, thermoplastics, and (polydimethylsiloxane) PDMS devices make rapidly optimizing and prototyping devices challenging. Microfluidic fabrication techniques have been a long-standing challenge in successfully translating these …

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A Comparison Of Fish Health Indices Applied To Freshwater Species Of The Chesapeake Bay Watershed, Josiah B. Jensen Jan 2023

A Comparison Of Fish Health Indices Applied To Freshwater Species Of The Chesapeake Bay Watershed, Josiah B. Jensen

Graduate Theses, Dissertations, and Problem Reports (ETD)

Fish kills, increased disease prevalence, and endocrine disruption have been observed in multiple freshwater fish populations of the Chesapeake Bay watershed (CBW). Some of these health issues occur in conjunction with declining abundance. A combination of multiple stressors is believed to be weakening sensitive fish species in non-tidal regions of the CBW. Fish health indices such as Deformity, Erosion, Lesion, and Tumor counts (DELTs), and the Health Assessment Index (HAI) are simple tools designed to evaluate the general health of fish populations. Both indices could be widely applied in the watershed because they require limited training and equipment. However, their …

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Association Of Income, Education, Employment And Covid-19 Mortality In Brazil, Marcelina Machado Jan 2023

Association Of Income, Education, Employment And Covid-19 Mortality In Brazil, Marcelina Machado

Walden Dissertations and Doctoral Studies

The increased mortality rates from COVID-19 in Brazil have adversely affectedvulnerable populations and placed a severe burden on its public health system as compared to other nations. Focusing on socioeconomic status as a risk factor in this retrospective cohort study, I investigated the association between Brazilian COVID-19 mortality rate, income, school enrollment rate, and employment rate after controlling for the demographics and immunization rate. This is an important issue as an increase in incidence and mortality rates affects how governmental and public health leaders can effectively control and prevent disease spread. Using the fundamental causes of disease theory as the …

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Localized Delivery Of Gm-Csf In The Regulation Of Breast Tumor Oxygen And Anti-Tumor Immunity Through Macrophages, Nicole E. Mihalik Jan 2023

Localized Delivery Of Gm-Csf In The Regulation Of Breast Tumor Oxygen And Anti-Tumor Immunity Through Macrophages, Nicole E. Mihalik

Graduate Theses, Dissertations, and Problem Reports (ETD)

GM-CSF has been employed as an adjuvant to cancer immunotherapies in solid tumors due to its ability to drive immune stimulatory macrophages and other myeloid cells that promote anti-tumor responses. However, GM-CSF does not always exert immune stimulatory effects on myeloid cells, and sometimes even drives immune suppressive phenotypes. GM-CSF effects on myeloid cells and the tumor microenvironment (TME) appear to vary across dosages and even cancer types. However, an optimal dosing regimen for GM-CSF has yet to be determined to-date, and this is further complicated by the fact that GM-CSF is often administered via oncolytic viruses or tumor vaccines …

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Study Of Barrier Face Coverings And Respirator Exhalation Filtration Efficiency And Exhaled Air Velocity During Wear, Weihua Yang Jan 2023

Study Of Barrier Face Coverings And Respirator Exhalation Filtration Efficiency And Exhaled Air Velocity During Wear, Weihua Yang

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study aimed to assess the effectiveness of different types of respiratory protection, including National Institute for Occupational Safety and Health (NIOSH) Approved respirators and surgical masks in healthcare settings, as well as barrier face coverings (BFCs) used by the public as source control. The assessment was based on three components: total outward leakage (TOL), particle size distribution, and exhalation airflow velocity. To achieve this, the study utilized headform testing systems to measure TOL and airflow velocity. Specifically, a hard surface headform was used for NIOSH Approved respirators and surgical masks, while two soft surface headforms of different sizes were …

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Development And Characterization Of Monoclonal Antibodies Against Pseudomonas Aeruginosa, Jason Kang Jan 2023

Development And Characterization Of Monoclonal Antibodies Against Pseudomonas Aeruginosa, Jason Kang

Graduate Theses, Dissertations, and Problem Reports (ETD)

Antimicrobial resistance (AMR) has emerged as a global crisis, posing significant challenges to the treatment and management of infectious diseases. The escalating prevalence of antibiotic-resistant bacteria has made many antimicrobial therapies ineffective, necessitating the development of alternative strategies to combat microbial infections. The rise of multidrug-resistant pathogens, such as Pseudomonas aeruginosa and Serratia marcescens, further exacerbates this problem, as these pathogens exhibit high levels of resistance to multiple antibiotics and cause severe infections in vulnerable populations. In response to the need for alternative therapeutic approaches, monoclonal antibodies (mAbs) have emerged as promising candidates for combating AMR. In this work, we …

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Machine Learning For Biosensors, Gayathri Anapanani Jan 2023

Machine Learning For Biosensors, Gayathri Anapanani

Graduate Theses, Dissertations, and Problem Reports (ETD)

Biosensors have become increasingly popular as diagnostic tools due to their ability to detect and quantify biological analytes in a wide range of applications. With the growing demand for faster and more reliable biosensing devices, machine learning has become a valuable tool in enhancing biosensor performance. In this report, we review recent progress in the application of machine learning to biosensors. We discuss the potential benefits of using machine learning in biosensors, including improved sensitivity, selectivity, and accuracy. We also discuss the various machine learning techniques that have been applied to biosensors, including data preprocessing, feature extraction, and classification and …

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Gender Dynamics In The Management Care Of Internally Displaced Persons: The Boko Haram Insurgency, Evelyn Kikelomo Ikuenobe Otaigbe Jan 2023

Gender Dynamics In The Management Care Of Internally Displaced Persons: The Boko Haram Insurgency, Evelyn Kikelomo Ikuenobe Otaigbe

Walden Dissertations and Doctoral Studies

The Boko Haram asymmetric insurgency and warfare have decimated the Northeastern region of Nigeria and its neighboring environs of Chad, Niger, and Benin. The purpose of this study was to explore the peculiar socioethnic and cultural challenges encountered by female victims of Boko Haram terrorism at internally displaced persons camps in Abuja, Nigeria, including challenges in functioning, relocating, and acclimating back into society. A phenomenological approach was applied to understand participants’ lived experiences. Data collection occurred through interviews and observation. Data analysis involved the synthesis of narratives, and generation of themes. Among the emergent themes were poor feeding; lack of …

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Cluster Homolog Of Immunoglobulin-Like Receptor Genes In Chicken Immune Responses, Brandi A. Sparling Jan 2023

Cluster Homolog Of Immunoglobulin-Like Receptor Genes In Chicken Immune Responses, Brandi A. Sparling

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation explores the identity and role of immunoglobulin-like (Ig-like) receptors in chickens, with focus on their implications in disease and disease progression. These receptors, wisely expressed across immune cells, interact with the major histocompatibility complex (MHC) class I molecules to modulate immune responses in mammals. Due to the insufficient representation of chicken Ig-like receptors in online databases, this study systematically annotates the chicken Cluster Homolog of Immunoglobulin-like Receptors (CHIR) genes using advanced bioinformatic techniques, aligning with the release of the 7th edition of the chicken genome assembly that comprises builds for a broiler and layer chicken. The analysis identifies …

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Comparing Activity-Based Market Segments On The George Washington And Jefferson National Forests Before And During The Covid-19 Pandemic, Eric Eugene Snyder Jan 2023

Comparing Activity-Based Market Segments On The George Washington And Jefferson National Forests Before And During The Covid-19 Pandemic, Eric Eugene Snyder

Graduate Theses, Dissertations, and Problem Reports (ETD)

Understanding market segments in forest-based tourism and their dynamics is integral for the tourism industry's ability to adapt and thrive in the ever-evolving market. The purpose of this research is to determine how recreation participation changed over a five-year period in the George Washington and Jefferson National Forests before and during the COVID-19 global pandemic. Data were collected via the National Visitor Use Monitoring (NVUM) surveys in fiscal years 2016 and 2021. NVUM surveys are on-site exit interview surveys that produce descriptive information about forest visitors. NVUM utilizes a stratified random sampling methodology that captures data across different use levels, …

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Catheter Associated Urinary Tract Infection Prevention Education, Mary Jo Roskos Jan 2023

Catheter Associated Urinary Tract Infection Prevention Education, Mary Jo Roskos

Walden Dissertations and Doctoral Studies

AbstractCatheter associated urinary tract infections (CAUTIs) are infections that happen in the urinary tract in men and women when foley catheterization is not done using strict aseptic techniques. Bacteria can then travel up the urinary catheter into the bladder; therefore, contaminating urine in the bladder. This project site’s nursing staff was experiencing a lack of knowledge regarding CAUTI prevention. This lack of knowledge on the importance of sterile technique when inserting urinary catheters can lead to CAUTIs. The project question for this project addressed whether the educational program on the importance of a strict sterile technique on urinary catheter insertion …

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Dietary Changes In Preventing Type Ii Diabetes Mellitus Among Young Hispanic Adults, Taiwo Onipede Jan 2023

Dietary Changes In Preventing Type Ii Diabetes Mellitus Among Young Hispanic Adults, Taiwo Onipede

Walden Dissertations and Doctoral Studies

Diabetes mellitus continues to be a major chronic disease affecting the global population today with more prevalence amongst minority groups in the United States. The genetic susceptibility to obesity and higher insulin resistance seen in the Hispanic population puts them at the highest risk for development of Type II Diabetes (T2DM). The alarming increase in young adult T2DM diagnosis led to the project question: How can teaching on dietary changes affect Type II Diabetes diagnosis in predisposed young Hispanic adults? The purpose of this project is to accomplish the goal of Healthy People 2020 towards improving the quality of life …

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Issues Encountered By Parents In Continuing School-Based Obesity Prevention Programs At Home, Prenu Skaria Jan 2023

Issues Encountered By Parents In Continuing School-Based Obesity Prevention Programs At Home, Prenu Skaria

Walden Dissertations and Doctoral Studies

Childhood obesity is a public health problem that can lead to various chronic health diseases such as cardiovascular disease and diabetes later in life. School-based obesity prevention programs are a public health recommendation to reduce and prevent obesity in schools through increased physical activity and better nutritional habits. This qualitative research involved exploring the reason for the discontinuation of school-based interventions at home using multi-theory model (MTM) constructs for health behavior change. A convenience sample of three focus groups of consenting parents whose children participated in the Wolf Pack Coaches Challenge (WPCC), a school-based obesity prevention program in Nevada, was …

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Laboratory Practices And Antimicrobial Resistance In A Florida Hospital, Crispina Marie Sy-Trias Jan 2023

Laboratory Practices And Antimicrobial Resistance In A Florida Hospital, Crispina Marie Sy-Trias

Walden Dissertations and Doctoral Studies

Antibiotic resistance is a health threat affecting millions of Americans. Microorganisms develop resistance to antibiotics, rendering them useless for treating infections. The purpose of this quantitative study was to assess the associations between sample processing time and antibiotic resistance and is based on the health belief model. A retrospective specimen tracking activity of data from November 2019 to November 2020 was obtained by random sampling of 246 bacterial cultures. One hundred ninety-six (80%) samples were processed on time, and 50 (20%) were delayed; 167 (68%) samples were determined to have the presence of antimicrobial resistance (AMR), and 79 (32%) with …

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Community Perceptions Of Syringe Service Programs In Charleston, West Virginia: A Qualitative Socioecological Perspective, Kenya M. Burton Jan 2023

Community Perceptions Of Syringe Service Programs In Charleston, West Virginia: A Qualitative Socioecological Perspective, Kenya M. Burton

Walden Dissertations and Doctoral Studies

In rural areas of the United States, people who inject drugs (PWID) experience an array of obstacles to accessing adequate healthcare. Locations with high rates of drug use normally offer more healthcare options, including needle exchange programs but, in some communities, there is resistance to providing this kind of care. This increases mortality, morbidity, cost, and adds to the stigma experienced by this vulnerable group. The experiences of people with substance dependency, including PWID, has been widely explored throughout studies that reflect a need for increased support. However, the perspectives of the community, especially in rural areas, though equally important, …

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Internal Population Displacement And Vaccination Completion, Malnutrition, And Respiratory Infections Among Children In The Central African Republic, Francois Xavier Batalingaya Jan 2023

Internal Population Displacement And Vaccination Completion, Malnutrition, And Respiratory Infections Among Children In The Central African Republic, Francois Xavier Batalingaya

Walden Dissertations and Doctoral Studies

Forced displacement in fragile and conflict-affected countries has the potential to disrupt access to basic primary healthcare services such as immunization. The purpose of this study was to assess the association between internal population displacement and vaccination completion, malnutrition, and acute respiratory infections (ARIs) while controlling for maternal characteristics of wealth index, education level, and residence status in the Central African Republic. The socioecological model underpinned this cross-sectional study that used a secondary dataset collected in 2018 – 2019 and maintained by UNICEF. Descriptive statistics and logistic regression tests were used to analyze the data. The findings of this study …

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Differential Expression Of Programmed Death 1 (Pd-1) On Various Immune Cells And Its Role In Human Leprosy, Mohammad Tarique, Huma Naz, Mohd Suhail, Ali Turan, Chaman Saini, Naoshad Muhammad, Hari Shankar, Torki A Zughaibi, Tabish H Khan, Neena Khanna, Alpana Sharma Jan 2023

Differential Expression Of Programmed Death 1 (Pd-1) On Various Immune Cells And Its Role In Human Leprosy, Mohammad Tarique, Huma Naz, Mohd Suhail, Ali Turan, Chaman Saini, Naoshad Muhammad, Hari Shankar, Torki A Zughaibi, Tabish H Khan, Neena Khanna, Alpana Sharma

2020-Current year OA Pubs

Leprosy is a chronic bacterial disease caused by

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Patent Term Extensions And The Last Man Standing, Robin Feldman Jan 2023

Patent Term Extensions And The Last Man Standing, Robin Feldman

Faculty Scholarship

In 1984, with the passing of the Hatch-Waxman Act, Congress orchestrated a compromise that permanently changed how drug markets operate. This piece of legislation created an expedited pathway for generics to enter the market, and, in exchange, brand drugs could extend their patents to account for time lost during their market approval process. Although this well-configured trade was supposed to help generics enter the scene quicker, the current drug market landscape makes one question whether this legislation has succeeded in its aims. The following study explores the lifecycle of top-selling brand drugs in comparison to the vision put forth by …

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Strategies To Mitigate Inappropriate Test Utilization By Physicians To Improve Efficiency In A Healthcare Setting, Christine C. Wood Jan 2023

Strategies To Mitigate Inappropriate Test Utilization By Physicians To Improve Efficiency In A Healthcare Setting, Christine C. Wood

Walden Dissertations and Doctoral Studies

Inappropriate test utilization by physicians for clinical decision-making in patient care is a significant problem facing some healthcare leaders. Healthcare leaders are concerned about inappropriate test utilization because it can increase healthcare costs and degrade patient outcomes. Grounded in the complex adaptive system and Lean Six Sigma conceptual frameworks, the purpose of this qualitative single-case study was to identify strategies seven hospital leaders in Maryland and Washington, DC. who implemented successful test utilization strategies for physicians. Data were collected from semistructured virtual interviews and organizational reports and analyzed using Yin’s 5 step process. Five themes emerged: (a) continuing physician education, …

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A Mixed Methods Study Investigating Sources Of Fertility And Reproductive Health Information In The Uk, B. Grace, J. Shawe, J. Stephenson Jan 2023

A Mixed Methods Study Investigating Sources Of Fertility And Reproductive Health Information In The Uk, B. Grace, J. Shawe, J. Stephenson

School of Nursing and Midwifery

No abstract provided.

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Nurses’ Perceptions Of The Skills, Knowledge And Attributes Required To Optimise Scope Of Practice And Improve Access To Care For People Experiencing Homelessness In Australia: A Cross-Sectional Study, Jane Currie, Lucy Mcwilliams, Martha Paisi, Jill Shawe, Anna Thornton, Matthew Larkin, Joanne Taylor, Sandy Middleton Jan 2023

Nurses’ Perceptions Of The Skills, Knowledge And Attributes Required To Optimise Scope Of Practice And Improve Access To Care For People Experiencing Homelessness In Australia: A Cross-Sectional Study, Jane Currie, Lucy Mcwilliams, Martha Paisi, Jill Shawe, Anna Thornton, Matthew Larkin, Joanne Taylor, Sandy Middleton

School of Nursing and Midwifery

Background People experiencing homelessness are less likely to access healthcare, particularly primary and preventive care. Nurses are well placed to improve access to healthcare for this vulnerable population. Aim To explore nurses’ perceptions of the skills, knowledge and attributes required to optimise scope of practice and improve access to healthcare for people experiencing homelessness, to underpin an education framework. Design A cross-sectional national survey of nurses in Australia. Methods Part of a larger study, a 222-item electronic survey was disseminated via social media and nursing colleges and associations. Participants rated the level of priority of specific skills knowledge and attributes …

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Social Worker Perspectives On Implementation Of Harm Reduction Into Abstinence-Based Substance Abuse Programs, Susan Woomer Jan 2023

Social Worker Perspectives On Implementation Of Harm Reduction Into Abstinence-Based Substance Abuse Programs, Susan Woomer

Walden Dissertations and Doctoral Studies

Opioid addiction is a growing epidemic in the United States and was declared a public health emergency by the Department of Health and Human Services in October of 2017. There is a growing recognition that the current treatment for heroin and opioid addiction, abstinence-based treatment programs, is not readily available and has minimal success in addressing the epidemic. Harm reduction therapy is recognized as an effective way to address the opioid epidemic. This study aimed to develop further insight and understanding of how to integrate harm reduction therapy in abstinence-based treatment programs. The theoretical framework for this study was the …

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Inhibition Of Mirna Associated With A Disease-Specific Signature And Secreted Via Extracellular Vesicles Of Systemic Lupus Erythematosus Patients Suppresses Target Organ Inflammation In A Humanized Mouse Model, Nicholas A Young, Emily Schwarz, Braden M Zeno, Shane Bruckner, Rosana A Mesa, Kyle Jablonski, Lai-Chu Wu, Elisha D O Roberson, Wael N Jarjour Jan 2023

Inhibition Of Mirna Associated With A Disease-Specific Signature And Secreted Via Extracellular Vesicles Of Systemic Lupus Erythematosus Patients Suppresses Target Organ Inflammation In A Humanized Mouse Model, Nicholas A Young, Emily Schwarz, Braden M Zeno, Shane Bruckner, Rosana A Mesa, Kyle Jablonski, Lai-Chu Wu, Elisha D O Roberson, Wael N Jarjour

2020-Current year OA Pubs

INTRODUCTION: Distinct, disease-associated intracellular miRNA (miR) expression profiles have been observed in peripheral blood mononuclear cells (PBMCs) of systemic lupus erythematous (SLE) patients. Additionally, we have identified novel estrogenic responses in PBMCs from SLE patients and demonstrated that estrogen upregulates toll-like receptor (TLR)7 and TLR8 expression. TLR7 and TLR8 bind viral-derived single-stranded RNA to stimulate innate inflammatory responses, but recent studies have shown that miR-21, mir-29a, and miR-29b can also bind and activate these receptors when packaged and secreted in extracellular vesicles (EVs). The objective of this study was to evaluate the association of EV-encapsulated small RNA species in SLE …

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The Prison Reentry Experience Of Justice-Involved Veterans, Latta Roosevelt Thomas Jr. Jan 2023

The Prison Reentry Experience Of Justice-Involved Veterans, Latta Roosevelt Thomas Jr.

Walden Dissertations and Doctoral Studies

Prison reentry programs attempt to equip justice-involved veterans with life skills necessary for their transition out of prison. This qualitative study addressed the scant understanding of the impact pre-released prison reentry programs have on justice-involved veterans’ transition and reintegration back to the community. The purpose of this qualitative study was to describe the perceptions of justice-involved veterans regarding prison reentry programs that have impacted their transition out of prison. The well-being development model and Castro’s military-to-civilian transition model provided the conceptual framework for this qualitative study, using semistructured questions to interview 11 justice-involved veterans regarding their participation in prison reentry …

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Strategies To Mitigate Inappropriate Test Utilization By Physicians To Improve Efficiency In A Healthcare Setting, Christine C. Wood Jan 2023

Strategies To Mitigate Inappropriate Test Utilization By Physicians To Improve Efficiency In A Healthcare Setting, Christine C. Wood

Walden Dissertations and Doctoral Studies

Inappropriate test utilization by physicians for clinical decision-making in patient care is a significant problem facing some healthcare leaders. Healthcare leaders are concerned about inappropriate test utilization because it can increase healthcare costs and degrade patient outcomes. Grounded in the complex adaptive system and Lean Six Sigma conceptual frameworks, the purpose of this qualitative single-case study was to identify strategies seven hospital leaders in Maryland and Washington, DC. who implemented successful test utilization strategies for physicians. Data were collected from semistructured virtual interviews and organizational reports and analyzed using Yin’s 5 step process. Five themes emerged: (a) continuing physician education, …

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Examination Of The Association Between Poverty, Income, And Education Levels On Tuberculosis Prevalence In Nigeria: Rural Niger Delta Case Study, Nwinmene George Zarakpege Jan 2023

Examination Of The Association Between Poverty, Income, And Education Levels On Tuberculosis Prevalence In Nigeria: Rural Niger Delta Case Study, Nwinmene George Zarakpege

Walden Dissertations and Doctoral Studies

Despite the global decline in tuberculosis (TB) cases, the prevalence of TB in rural populations in Nigeria is rising. To date, poverty and low educational levels continue to affect treatment and other prevention strategies to eradicate the disease. The purpose of this cross-sectional study was to assess the association between poverty, educational levels, household structure and vaccination status on TB prevalence in rural Niger Delta, Nigeria. The theoretical framework for this study was the socio-ecological model. Data were obtained from residents of rural Niger Delta in Nigeria attending a teaching hospital in southern Nigeria. The relationship between the stated demographic …

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The Application Of Time Series Analysis To Injury Epidemiology Data, Eric Wayne Lundstrom Jan 2023

The Application Of Time Series Analysis To Injury Epidemiology Data, Eric Wayne Lundstrom

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction: Injury fatality rates in the United States (US) decreased throughout the majority of the 20th century, mostly due to declining rates of occupational and motor vehicle injuries. However, near the beginning of the 21st century, fatal injury rates in the US began to increase. This is principally due to the nation’s opioid epidemic, which has been characterized by different epidemic “waves”, each driven by overdoses associated with specific substances. Given the temporally dynamic nature of US injury trends, this study aimed to explore the application of time series analysis to injury data in the US. First, rates of non-fatal …

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Anxiety Risk Factors And Social Isolation Among Young Adults, Jennifer Clancy Jan 2023

Anxiety Risk Factors And Social Isolation Among Young Adults, Jennifer Clancy

Walden Dissertations and Doctoral Studies

The COVID-19 pandemic is a public health concern that impacted the world. Increased feelings of loneliness and social isolation during the pandemic were reported to be associated with those seeking help for symptoms of anxiety and depression. Though symptoms of anxiety have been associated with social isolation, research is limited on the association between the anxiety risk factors and social isolation among young adults in the United States. Using the socioecological model, the association between social isolation (dependent variable) with financial stress, health anxiety, and perceived impact of COVID-19 (independent variable), and the influence of gender, race, and household status …

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