Digital Commons Network^™

Prevalence Of Depressive Symptoms And Correlates Among Individuals Who Self-Reported Sars-Cov-2 Infection After Optimizing The Covid-19 Response In China, Liangjia Wei, Jiao Qin, Zhifeng Lin, Xinju Huang, Jinfeng He, Dee Yu, Fei Zhang, Sisi Li, Ping Cen, Mu Li, Tong Luo, Rongjing Zhang, Shanmei Zhong, Cai Qin, Zeyu Li, Yuan Yang, Huiqi Pan, Mengdi Zhao, Xiaoqiong Wu, Junjun Jiang, Hao Liang, Li Ye, Bingyu Liang

Faculty, Staff and Student Publications

BACKGROUND: The burden of depression symptoms has increased among individuals infected with SARS-CoV-2 during COVID-19 pandemic. However, the prevalence and associated factors of depressive symptoms among individuals infected with SARS-CoV-2 remain uncertain after optimizing the COVID-19 response in China.

METHODS: An online cross-sectional survey was conducted among the public from January 6 to 30, 2023, using a convenience sampling method. Sociodemographic and COVID-19 pandemic-related factors were collected. The depression symptoms were assessed using the Patient Health Questionnaire-9 (PHQ-9). Logistic regression analysis was performed to explore the associated factors with depressive symptoms.

RESULTS: A total of 2,726 participants completed the survey. …

Whose Public Virtue? Exploring Freedom Of Information Efficacy And Support, A.Jay Wagner

College of Communication Faculty Research and Publications

Little is known about public perceptions of how FOI laws influence government operations or impact citizens’ daily lives. A large representative sample of U.S. adults was surveyed for support of FOI laws and perceptions of FOI efficacy. Findings showed advanced education and higher perceptions of general government efficacy to be strongly significant in predicting both support for FOI and greater FOI efficacy. Males and liberal respondents also demonstrated significance in predicting support for FOI and higher FOI efficacy, while Black race was a significant negative predictor in support for FOI and whether FOI improved government operations and accountability.

The Use Of A Habitat Quality Stress Index To Evaluate Stress As An Analog For Proximate Fitness In The American Crow Within A Matrix Of Landcover Characteristics To Assess Its Potential Contribution To Disease Etiologies, Theodore Lee Grabarz

Antioch University Dissertations & Theses

All organisms occur within spatial and temporal environments to maximize proximate fitness (health) and thus life history outcomes. Previous work has examined the temporal and behavioral aspects of proximate fitness on life history outcomes particularly regarding highly perturbed environments (i.e., climate and land use change, resource extraction, agricultural erosion, etc.). My work focuses on the less examined spatial aspect of these perturbed environments. More specifically, this dissertation examines habitat selection and quality as the basis for understanding stress response (negative and positive feedback mechanisms) to environmental stressors within the larger context of regional or gamma (ɣ) biodiversity. Through the lens …

Connecting Antibiotic Resistance To The Environment (Care): Introducing A Novel Framework Integrating Chemical Cross-Resistance And Place-Based Engagement To The Blue Marsh Watershed In Reading, Pennsylvania, Jill Felker

Antioch University Dissertations & Theses

Antibiotic resistance is a serious health threat around the world. Millions of individuals are infected with antibiotic-resistant bacteria yearly, and thousands die from previously curable illnesses. Although antibiotic resistance occurs naturally, misuse of antibiotics accelerates the loss of their effectiveness. Public health campaigns focusing on antibiotic awareness have not effectively communicated and educated the public on this health crisis. New efforts to combat antibiotic resistance are urgently needed. This dissertation focuses on the ecological and public health components of antibiotic resistance research that must be addressed to decelerate antibiotic resistance. A new interdisciplinary theoretical framework was developed to Connect Antibiotic …

Covid-19 Two Years On: A Review Of Covid-19-Related Empirical Research In Major Tourism And Hospitality Journals, Songshan (Sam) Huang, Xuequn Wang

Research outputs 2022 to 2026

Purpose: This study aims to provide a timely review of the COVID-19-related empirical research published in 19 quartile one (Q1) and quartile two (Q2) tourism and hospitality journals in social science citation index (SSCI).

Design/methodology/approach: A total of 407 COVID-19-related empirical papers were collected from the 19 SSCI Q1 and Q2 tourism and hospitality journals via Scopus database. Thematic content analysis was supplemented with Leximancer software to identify the research themes/subthemes, research methods and countries/regions of research.

Findings: The study found studies of COVID-19’s impact on consumer behaviour predominate in number, followed by studies on response actions and recovery strategies, …

Tourism Experiences Reduce The Risk Of Cognitive Impairment In The Chinese Older Adult: A Prospective Cohort Study, Qian Li, Zheng Guo, Fangli Hu, Mengfei Xiao, Qiang Zhang, Jun Wen, Tianyu Ying, Danni Zheng, Youxin Wang, Song Yang, Haifeng Hou

Research outputs 2022 to 2026

Background: Given the etiological complexity of cognitive impairment, no effective cure currently exists for precise treatment of dementia. Although scholars have noted tourism’s potential role in managing cognitive impairment and mild dementia, more robust empirical investigation is needed in this area. This study aimed to examine the associations between tourism and cognitive impairment and dementia in older Chinese adults. Method: From a nationwide community-based cohort, 6,717 individuals aged ≥ 60 were recruited from 2011 to 2014, of whom 669 (9.96%) had had at least one tourism experience in the 2 years prior to enrollment. All the participants were then prospectively …

Editorial: Computational Predictions, Dynamic Tracking, And Evolutionary Analysis Of Antibiotic Resistance Through The Mining Of Microbial Genomes And Metagenomic Data, Volume Ii, Qi Zhao, Jian Li, Alfred Tay, Liang Wang

Research outputs 2022 to 2026

Antibiotic resistance has emerged as a critical global health challenge, posing a significant threat to human and animal health. The rapid development of antibiotic resistance among pathogens has reduced the efficacy of existing treatments, leading to an urgent need for novel therapeutic strategies. One promising avenue of research involves mining microbial genomes and metagenomic data to uncover novel antimicrobial agents and a better understanding of the resistance mechanism.

Corrigendum: Evolution, Ecology, And Zoonotic Transmission Of Betacoronaviruses: A Review, Herbert F. Jelinek, Mira Mousa, Eman Alefishat, Wael Osman, Ian Spence, Dengpan Bu, Samuel F. Feng, Jason Byrd, Paola A. Magni, Shafi Sahibzada, Guan K. Tay, Habiba S. Alsafar

Research outputs 2022 to 2026

In the published article, there was an error in the legend for Figure 1 as published. The figure legend did not indicate that it has been adapted from Plowright et al. (2017). Copyright permission was obtained from Springer Nature to adapt Figure 1 from Plowright et al. (2017). The corrected legend appears below. Figure 1. Zoonotic risk distribution, pathway to spillover, and the multimodal role of the determinants of spillover. The zoonotic risk is demonstrated by the accumulated distribution of reservoir hosts and vectors that play a role in the pathway to spillover. The risk of spillover is determined by …

Covid-19 Lessons To Protect Populations Against Future Pandemics By Implementing Pppm Principles In Healthcare, Cuihong Tian, Lois Balmer, Xuerui Tan

Research outputs 2022 to 2026

The coronavirus disease 2019 (COVID-19) pandemic has continued for more than 3 years, placing a huge burden on society worldwide. Although the World Health Organization (WHO) has declared an end to COVID-19 as a Public Health Emergency of International Concern (PHEIC), it is still considered a global threat. Previously, there has been a long debate as to whether the COVID-19 emergency will eventually end or transform into a more common infectious disease from a PHEIC, and how should countries respond to similar pandemics in the future more time-efficiently and cost-effectively. We reviewed the past, middle and current situation of COVID-19 …

The Servant Of God As A Proactive Manager: A Team Service Solution Model For Meeting Covid-19 Challenges In Indonesia, Muner Daliman, Jonathan James

Research outputs 2022 to 2026

Hundreds of thousands of people from all walks of life have died in Indonesia from Covid−19; work practices have been disrupted and various changes have occurred, including the sphere of service in churches, foundations, schools, and universities. The study aims to understand the concept of the proactive manager as a servant of God: a representative and spokesman for God who is obliged to plan, implement, and evaluate what he/she is doing in carrying out what God wills during the challenges of the Covid−19 era in Indonesia. The research method used was content analysis from secular and biblical texts. The results …

Summary Of Aboriginal And Torres Strait Islander Health Status - Selected Topics 2022, Australian Indigenous Healthinfonet

Research outputs 2022 to 2026

The Summary of Aboriginal and Torres Strait Islander health status - selected topics 2022 (Summary) is a useful resource for those working or studying in the Aboriginal and Torres Strait Islander health sector. It provides general information regarding the health status of Aboriginal and Torres Strait Islander people covering the following topics:

• the Aboriginal and Torres Strait Islander population
• determinants of health
• information pertaining to births and pregnancy, deaths and hospitalisation
• burden of disease
• chronic conditions including cardiovascular disease, cancer, diabetes, kidney and respiratory health
• social and emotional wellbeing (including mental health)
• selected sexually transmissible infections
• environmental health
• tobacco and …

Australian Highlevel Public Policy Preparedness For Population-Based Triage During The Pandemic, Zachary Horn, Lily Gapp Duckett, Kaitlin Webber

Research outputs 2022 to 2026

The COVID-19 pandemic brought attention to scarce clinical resource allocation via secondary population-based triage (S-PBT) throughout the international healthcare community. Experiences overseas highlighted the importance of coordinated and consistent approaches to allocating resources when facing overwhelming demand, particularly for critical care. Noting the importance of consistency and the system of devolved governance deployed in Australia, this study aimed to identify and analyse sources of high-level policy that affect Australia’s health system preparedness for the operationalisation of S-PBT. Of the 39 documents reviewed, 17 contained potential references to S-PBT. There was a lack of clear recommendations and guidance to inform S-PBT …

Identification And Validation Of Igg N-Glycosylation Biomarkers Of Esophageal Carcinoma, Huiying Pan, Zhiyuan Wu, Haiping Zhang, Jie Zhang, Yue Liu, Zhiwei Li, Wei Feng, Guiqi Wang, Yong Liu, Deli Zhao, Zhiyi Zhang, Yuqin Liu, Zhe Zhang, Xiangtong Liu, Lixin Tao, Yanxia Luo, Xiaonan Wang, Xinghua Yang, Feng Zhang, Xia Li, Xiuhua Guo

Research outputs 2022 to 2026

Introduction: Altered Immunoglobulin G (IgG) N-glycosylation is associated with aging, inflammation, and diseases status, while its effect on esophageal squamous cell carcinoma (ESCC) remains unknown. As far as we know, this is the first study to explore and validate the association of IgG N-glycosylation and the carcinogenesis progression of ESCC, providing innovative biomarkers for the predictive identification and targeted prevention of ESCC. Methods: In total, 496 individuals of ESCC (n=114), precancerosis (n=187) and controls (n=195) from the discovery population (n=348) and validation population (n=148) were recruited in the study. IgG N-glycosylation profile was analyzed and an ESCC-related glycan score was …

A Scoping Review Of Nurse-Led Randomised Controlled Trials, Marion Eckert, Kate Kennedy, Kim Neylon, Claire M. Rickard, Samantha Keogh, Richard Gray, Sandy Middleton, Caroline Homer, Lisa Whitehead, Greg Sharplin

Research outputs 2022 to 2026

Background: Nurses comprise the largest portion of the healthcare workforce worldwide. However, nurse representation in the leadership of clinical research and research funding is largely unknown. The Australasian Nursing and Midwifery Clinical Trials Network was established to provide a coordinated network, focussed on building research capacity in nursing and midwifery. To support this work, this scoping review of nurse-led randomised controlled trials was conducted to summarise research activity, as well as highlight future research directions, gaps and resources. Midwife-led trials will be reported elsewhere. Aim: To quantify number, type and quality of nurse-led randomised controlled trials registered between 2000–2021. Design: …

Hand Hygiene Knowledge And Demonstrated Technique Among Malawian Kindergarten Children: A Quasi-Experimental Study, Balwani Chingatichifwe Mbakaya, Maggie Zgambo, Fatch Welcome Kalembo

Research outputs 2022 to 2026

Aim: To evaluate hand hygiene knowledge and demonstrated technique before and after implementation of the hand hygiene programme and its sustainability among Malawian kindergarten students. Design: Quasi-experimental design, utilizing a repeated measure at three points, namely, before intervention (T0), soon after intervention (T1) and follow-up (T2). Methods: The hand hygiene programme consisted of integrating hand hygiene protocol into the school health curriculum, setting up proper handwashing facilities, training school teachers, health talks and developing reminders on hand hygiene. Fifty-three kindergarten children aged 3–6 years were enrolled in the programme. Data were collected at 3 months' intervals (T0, T1, and T2). …

Staff Perceptions Of The Effectiveness Of Managerial Communication During The Covid-19 Pandemic: A Cross-Sectional Study, Gemma Doleman, Linda Coventry, Amanda Towell-Barnard, Manonita Ghosh, Lucy Gent, Rosemary Saunders, Beverly O'Connell

Research outputs 2022 to 2026

Aims: This work aims to explore staff perceptions of (1) the effectiveness of organizational communication during the COVID-19 pandemic and (2) the impact of organizational communication on staff well-being and ability to progress their work and patient care. Background: Effective coordination and communication are essential in a pandemic management response. However, the effectiveness of communication strategies used during the COVID-19 pandemic is not well understood. Design: An exploratory cross-sectional research design was used. A 33-item survey tool was created for the study. Methods: The study was conducted at a tertiary teaching hospital in Western Australia. Convenience sampling was used to …

Antimicrobial Resistance: Public Health Review Of Policy, Education, And Treatment [Senior Thesis], Elizabeth Mari '23, Leah M. Seebald (Thesis Advisor)

Chemistry Faculty Scholarship

This thesis is broken into two sections. Part 1 is public health focused, utilizing a literature review(part 1a) and a population based survey(part 1b). Part 2 looks at the synthesis of natural product, (R)-Dysidazirine.

Tuberculosis In Lemurs And A Fossa At National Zoo, Madagascar, 2022, Marni Lafleur, Et Al.

Anthropology: Faculty Scholarship

We diagnosed Mycobacterium tuberculosis in captive lemurs and a fossa in Antananarivo, Madagascar. We noted clinical signs in the animals and found characteristic lesions during necropsy. The source of infection remains unknown. Our results illustrate the potential for reverse zoonotic infections and intraspecies transmission of tuberculosis in captive wildlife.

Bibliography Of Scholarship From 2023, University Of San Diego

Annual Bibliography of USD Scholarship

No abstract provided.

Building Consensus Around The Assessment And Interpretation Of Symbiodiniaceae Diversity, Cawa Tran, Et Al.

Biology: Faculty Scholarship

Within microeukaryotes, genetic variation and functional variation sometimes accumulate more quickly than morphological differences. To understand the evolutionary history and ecology of such lineages, it is key to examine diversity at multiple levels of organization. In the dinoflagellate family Symbiodiniaceae, which can form endosymbioses with cnidarians (e.g., corals, octocorals, sea anemones, jellyfish), other marine invertebrates (e.g., sponges, molluscs, flatworms), and protists (e.g., foraminifera), molecular data have been used extensively over the past three decades to describe phenotypes and to make evolutionary and ecological inferences. Despite advances in Symbiodiniaceae genomics, a lack of consensus among researchers with respect to interpreting genetic …

A Mixed Methods Study Investigating Sources Of Fertility And Reproductive Health Information In The Uk, B. Grace, J. Shawe, J. Stephenson

School of Nursing and Midwifery

No abstract provided.

Natural Resource Curse: A Literature Survey And Comparative Assessment Of Regional Groupings Of Oil-Rich Countries, Marwan Alssadek, James Benhin

Plymouth Business School

This paper provides an extensive review of the rapidly growing literature on the resource curse phenomenon, whereby natural resources-rich countries experience lower levels of economic growth and development than countries with fewer natural resources. The various theoretical explanations for the phenomenon, alongside a survey of the empirical literature, are critically discussed. Generally, the literature results are found to be mixed and no consensus is reached. This might be attributed to different time periods, data used, proxy for the natural resource variables selected and the estimation approach employed. The practical part of this paper applies a descriptive analysis to compare economic …

Proposing An Rna Interference (Rnai)-Based Treatment For Human Immunodeficiency Virus (Hiv) By Analyzing The Post-Transcriptional Gene Targeting Of Sars-Cov-2, Hepatitis C Virus, And A549 Lung Cancer Cells, Arjun Jagdeesh

UROP Posters

Human Immunodeficiency Virus (HIV) is a retrovirus that infects CD4+ T cell lymphocytes in humans, leading to the development of Acquired Immunodeficiency Syndrome (AIDS) if left untreated. While current treatment methods, including antiretroviral combination treatments, effectively limit HIV replication, HIV can evade these treatments due to its high mutation rate. Long-term antiretroviral treatment can also be toxic to patients, meaning patients would benefit from a new mechanism of HIV treatment. RNA interference (RNAi) is an antiviral pathway found in mammals, plants, and insects that involves a small-interfering RNA that is incorporated into a protein complex called the RNA-induced Silencing Complex …

A Smart Decade: Outcomes Of An Integrated, Inclusive, First-Year College-Level Stem Curricular Innovation, Shannon Jones, Alexis Blake, Lesly Corado-Santiago, Jasmine Crenshaw, Emma Goldman, Fernando Gomez, Chelsea Hall, Harry Hoke, Stephen Holmes, Benjamin Kornegay, Priscilla Kwarteng, Barry Lawson, Meghan Leber, Georges Leconte, Erica Modeste, Kristine Nolin, Michael Norris, Jose Santinni Roma, Addison Swackhammer, Marcella Torres, Joanna Wares, Dominique Ebony Williams, April Hill, Kathy Hoke, Carol Parish, B. Daniel Pierce

All Faculty Scholarship

In the early 2000s, our primarily undergraduate, white institution (PUI/PWI), began recruiting and enrolling higher numbers of students of color and first-generation college students. However, like many of our peer institutions, our established pedagogies and mindsets did not provide these students an educational experience to enable them to persist and thrive in STEM. Realizing the need to systematically address our lack of inclusivity in science majors, in 2012 faculty from multiple disciplines developed the Science, Math, and Research Training (SMART) program. Here, we describe an educational innovation, originally funded by a grant from the Howard Hughes Medical Institute, designed to …

Signature Of Energetic Materials Under Pyrolysis And Ambient Conditions, Athina Kominia

Open Access Dissertations

Law enforcement and military personnel must be prepared to deal with explosives, unidentified chemicals, and even chemical warfare agents. This is a vast problem space. The included studies examine issues with characterization, mitigation, and disposal of energetic materials.

Among oxidizers those containing the ammonium cation have the potential of self-oxidization, making them of special hazard. We have examined ammonium nitrite and ammonium chlorate, two ionic compounds with well-known hazard potential, and compare their explosive performance with related materials. A novel protocol for assessment of explosivity on the gram-scale was employed.

Law enforcement and military personnel must deal with scenarios where …

Cranberry Vine And Its Effects On The Periparturient Ovine And Her Offspring, Delaney Smith

Open Access Dissertations

Gastrointestinal nematodes (GIN) are a major health concern globally, particularly for small ruminant producers. The most deadly of these GIN is an anemia-inducing parasite called Haemonchus contortus. Infections of H. contortus are most severe during what's known as the periparturient period (PPP), which is the last 6 weeks of gestation and first 8 weeks of lactation in maternal animals. Widespread genetic resistance of H. contortus to the traditionally used chemical dewormers have led producers and researchers alike to turn to the plant kingdom for answers. Plant based compounds have been used as bioactive compounds for centuries to cure a …

Defining The Essential Genome Of Haemophilus Parainfluenzae And Conditionally Essential Genes Required For Its Survival In Biofilms And Serum Complement, Thaís Harder De Palma

Open Access Dissertations

Haemophilus parainfluenzae (Hp), a Gram-negative bacterium is found in different niches of the mouth, and it is very abundant in the supragingival plaque. While considered a commensal in the mouth, Hp is also a HACEK microorganism associated with endocarditis and considered an opportunistic pathogenic species. However, Hp remains a subject of limited investigation. Specifically, the genes necessary for Hp's survival and those that are conditionally essential for thriving under various environmental conditions are yet to be identified. This research addresses those questions using transposon sequencing (TnSeq) to identify the essential genome and the core essential genome in …

Development Of Localized Drug Delivery Strategies For The Treatment Of Cancers And Infectious Diseases, Weizhou Yue

Open Access Dissertations

Difficult-to-treat human diseases and disorders such as brain cancer and posterior segment eye diseases greatly threaten human health and quality of life. However, the presence of physiological barriers such as the blood-brain barrier (BBB), cornea, and the blood-retinal barrier, renders these organs highly impervious to most therapeutics. As a result, most therapeutics administered systemically have low therapeutic efficacy even with high doses and are often associated with systemic side effects and/or toxicity. Localized drug delivery strategies such as injectables/implants, or locally-acting dosage forms, can circumvent physiological barriers and directly introduce therapeutics to the site of action to improve bioavailability, and …

Measuring The Needle In The Haystack: Surface Enhanced Raman Spectroscopy (Sers) Detection Of Anionic Environmental Pollutants, Timo Küster

Open Access Dissertations

Detection of anionic environmental pollutants such as nitrate in seawater is essential to monitoring and maintaining water quality in coastal ecosystems. Current on-site methods for nutrient detection often require extensive sample preparation and have detection limits above concentration thresholds associated with nutrient limited conditions where small variations in concentration can lead to sudden ecological events, such as toxic algae blooms.

Surface Enhanced Raman Spectroscopy (SERS) is based on the enhancement of otherwise weak Raman scattering in the presence of nanostructured metal surfaces where analytes are within approximately 2 nm of the surface. For in situ measurements in an aqueous phase, …

Clonal Diversity, Antibiotic Resistance, And Virulence Factor Prevalence Of Community Associated Staphylococcus Aureus In Southeastern Virginia, Katelyn D. Cranmer, Mohan D. Pant, Suzanne Quesnel, Julia A. Sharp

EVMS School of Health Professions Faculty Publications

Staphylococcus aureus is a significant human pathogen with a formidable propensity for antibiotic resistance. Worldwide, it is the leading cause of skin and soft tissue infections (SSTI), septic arthritis, osteomyelitis, and infective endocarditis originating from both community- and healthcare associated settings. Although often grouped by methicillin resistance, both methicillin-resistant (MRSA) and methicillin-sensitive (MSSA) strains are known to cause significant pathologies and injuries. Virulence factors and growing resistance to antibiotics play major roles in the pathogenicity of community-associated strains. In our study, we examined the genetic variability and acquired antibiograms of 122 S. aureus clinical isolates from SSTI, blood, and urinary …