Digital Commons Network^™

Trust And Subjective Knowledge Influence Perceived Risk Of Lead Exposure, Madeline Goebel, Chloe B. Wardropper

National Drought Mitigation Center: Faculty Publications

Lead exposure is a persistent environmental hazard that poses risks to human health. But motivating protective action is challenging with this low visibility hazard whose health effects are often subtle and chronic. Higher risk perception is generally associated with taking protective measures, so public health efforts prioritize risk messaging. Yet, little is known about perceptions of lead exposure risk among the U.S. public. Using cross-sectional data from a national survey of 1035 U.S. residents, we measured the role of trust in government management of lead and subjective knowledge about lead as predictors of perceived risk of lead exposure, controlling for …

Impact Of Medicaid Expansion On Substance Abuse Treatment, Kyle Chapman

Theses, Dissertations and Capstones

Introduction: The Medicaid expansion has insured millions of Americans since the passage of the Affordable Care Act in 2010. Among this newly insured population, many of the enrollees have been diagnosed with a substance abuse disorder. Patients who have a substance use disorder diagnosis typically have multiple conditions that are treated simultaneously. When these patients have to seek healthcare services they are often uninsured. Unfortunately, since the patients are uninsured, the most frequent healthcare access points have been through admissions to more expensive areas of healthcare delivery such as the emergency department and subsequent inpatient services. The goals of the …

"We Don't Know What We Want": The Tug Between Rights And Public Health Online, Jonathan Zittrain

Duquesne Law Review

Twitter and Facebook boast billions of subscribers, many of whom are real people. The companies are also roundly hated, particularly by tech experts-at least those who follow them for something other than their stock performance.¹ Objections to platforms' behavior are commonly expressed as amazement that they could be so obviously and consistently wrong in failing to police awful content their users post. There is also amazement about unobjectionable posts and comments from users that they take down.² That, in turn, has led to pressure for regulatory initiatives to push the companies into doing what they so clearly ought …

Hiv And Addiction Services For People Who Inject Drugs: Healthcare Provider Perceptions On Integrated Care In The U.S. South, Davis Bradford, Mariel Parman, Sara Levy, Wesli H. Turner, Li Li, Leah Leisch, Ellen Eaton, Kaylee B. Crockett

APC Fund

This qualitative study evaluates physician training and experience with treatment and prevention services for people who inject drugs (PWID) including medications for opioid use disorder (MOUD) and HIV pre-exposure prophylaxis (PrEP). The Behavioral Model of Healthcare Utilization for Vulnerable Populations was applied as a framework for data analysis and interpretation. Two focus groups were conducted, one with early career physicians (n = 6) and one with mid- to late career physicians (n = 3). Focus group transcripts were coded and analyzed using thematic analysis to identify factors affecting implementation of treatment and prevention services for PWID. Respondents identified that increasing …

Exploring Inmate Health In Prison: Health Issues, Interventions, And Suggestions To Improve Care, Jenna Healy

Undergraduate Review

No abstract provided.

Autonomy And Paternalism In Medicine, Claire Consadine

Soaring: A Journal of Undergraduate Research

No abstract provided.

Surviving The Apprehensive Methicillin-Sensitive Staphylococcus Aureus (Mssa) Bacteremia: A Case Of Bacteremia With An Undetermined Source Of Infection Leading To Suspected Cardioembolic Ischemia And Biochemical Septic Shock, Greisy D. Curbelo Sesin, Eduardo Marino-Urbino, Christopher Fontela, Melanio J. Rodriguez, Jorge A. Diaz, Shivaan C. Oomrigar, Ramon Mendoza Bello, Yoandy Rodriguez Fuentes

East Florida Division GME Research Day 2023

Introduction: This research presents a complex case of a 70-year-old male with acute metabolic encephalopathy and biochemical septic shock, later attributed to cardioembolic ischemia, resulting from Methicillin-Sensitive Staphylococcus Aureus (MSSA) bacteremia with an elusive source of infection.

Case Description: The 70-year-old patient, with a medical history of hypertension and aortic valve stenosis status post-Coronary Artery Bypass Grafting and bioprosthetic valve replacement on dual anti-platelet therapy (clopidogrel and aspirin), was admitted following an unwitnessed fall and a day of vomiting and generalized weakness. Upon arrival, the patient exhibited altered mental status, hypotension, and acidosis. Initial diagnostic workup raised suspicion of biochemical …

Atraumatic Splenic Rupture: An Unaccustomed Complication Of H. Parainfluenzae Endocarditis, Daniel P. High, Jose M. Acosta-Rullan, Danay Herrera, Mauricio Danckers

East Florida Division GME Research Day 2023

No abstract available.

Unique Presentation Of Cerebritis: A Case Report, Wajahat Dawood, Kevin Jiang, Bryan Kharbanda

Gulf Coast Division GME Research Day 2023

No abstract provided.

Influences Of Host Cytokine Signaling On Kshv Infection In Tonsil-Derived B Lymphocytes, Nedaa Alomari

Pharmaceutical Sciences (PhD) Dissertations

Kaposi sarcoma-associated herpesvirus (KSHV) is the etiologic agent of kaposi sarcoma. It is also associated with the B cell lymphoproliferative disorders, primary effusion lymphoma (PEL), multicentric Castleman disease (MCD) and KSHV inflammatory cytokine syndrome (KICS). Existing research reveals that KSHV has developed numerous strategies to alter host cytokine signaling activities to facilitate viral persistence and escape host immune surveillance.

Despite three decades of research, there are still many questions in this field awaiting further investigation. This dissertation will investigate host cytokines as factors influencing the establishment of KSHV infection in the human tonsil. We have identified and characterized different cytokines …

2023 Intersession Catalog, Illinois Math And Science Academy

Intersession Catalogs

No abstract provided.

Comparison Of Clinical Study Results Reported In Medrxiv Preprints Vs Peer-Reviewed Journal Articles, Guneet Singh Janda

Yale Medicine Thesis Digital Library

The aim of this project was to evaluate the concordance among study characteristics, results, and interpretations described in preprints of clinical studies that are subsequently published in peer-reviewed journals (preprint-journal article pairs).

In this cross-sectional analysis, preprints posted on medRxiv in September 2020 were identified. Four evaluators determined how many preprints were subsequently published in peer-reviewed journals as of September 2022, calculating the time from preprint posting to publication. For preprints with multiple versions, the most recent version prior to journal acceptance was selected. Preprints updated after journal acceptance were excluded. For preprint-journal article pairs describing clinical trials, observational studies, …

Enhanced Learning In Biochemistry Using The Protein Data Bank And 3d Molecular Modeling In Chimerax, Frank Cappuccio, Jenny Cappuccio, Christopher Arias, Ezekiel Buchert, Johana Cruz-Lopez, Cesar Fernandez, Elizabeth Kowalski, Elizabeth Tesla Nicholas, Gabrielle Onnenga, Kellie Pierson

IdeaFest 2023

The Protein Data Bank (PDB) is a repository of atomic level resolution biological structures determined by researchers around the world. Protein macromolecular structures have become an essential tool for biotechnology fields. They are used to understand the chemical and biological processes in living systems and disease, and for precise drug design. Here students utilized the molecular modeling software UCSF ChimeraX to visualize 3D PDB protein structures of their choice. Students produced Quad Chart presentations and printed 3D models to allow for deep learning in protein structure.

An Ode To Oysters And Their Herpes, Victoria Cifelli

IdeaFest 2023

A comparison of the topography and microbial community of oyster gills with and without OsHV-1.

Flush It! Managing Antibiotic Residual Volume In Acute Care, Breanna Lien

IdeaFest 2023

This project considers the implication of administering small-volume antibiotics as an intermittent primary intravenous infusion. This method leaves significant residual volume in the IV tubing which leads to deviations from the prescribed dose and rate of administration. This is a common practice in acute care. A possible quality improvement project design using evidence-based practice is exhibited. The goal of the QI project would be to standardize policy, procedure, and administration of small-volume antibiotics to ensure consistent care and treatment for every patient.

Analysis Of A G-Protein Coupled Receptor, Cb2, David Lopez, Amanda Ratcliff, Frank E. Cappuccio, Jenny A. Cappuccio

IdeaFest 2023

The CB2 G-protein coupled receptors (GPCR) is found in the brainstem & hippocampus and is devoid of psychotropic effects but is less studied than the CB1 receptor. CB2 is inducible in CNS microglia following inflammation or injury, indicating a role in pain response. Here we sought to analyze CB2 using ChimeraX structures and overcome GPCR protein insolubility in extraction. The pET28a-CNR2, plasmid created and transformed into E.coli pLysS, was confirmed by restriction digest. Purification of CB2 micelles was achieved by affinity chromatography with detergent (43 kD). We aim to utilize nanodiscs to stabilize CB2, allowing studies of the molecular underpinnings …

Modelling Of Covid-19 Using Fractional Differential Equations, Rishi Patel, P. Sainani, M. Brar, R. Patel, X. Li, J. Drozd, F. A. Chishtie, A. Benterki, T. C. Scott, S. R. Valluri

Physics and Astronomy Publications

In this work, we have described the mathematical modeling of COVID-19 transmission using fractional differential equations. The mathematical modeling of infectious disease goes back to the 1760s when the famous mathematician Daniel Bernoulli used an elementary version of compartmental modeling to find the effectiveness of deliberate smallpox inoculation on life expectancy. We have used the well-known SIR (Susceptible, Infected and Recovered) model of Kermack & McKendrick to extend the analysis further by including exposure, quarantining, insusceptibility and deaths in a SEIQRDP model. Further, we have generalized this model by using the solutions of Fractional Differential Equations to test the accuracy …

Researching Covid To Enhance Recovery (Recover) Adult Study Protocol: Rationale, Objectives, And Design, Leora I Horwitz, Tanayott Thaweethai, Shari B Brosnahan, Mine S Cicek, Megan L Fitzgerald, Jason D Goldman, Rachel Hess, S L Hodder, Vanessa L Jacoby, Michael R Jordan, Jerry A Krishnan, Adeyinka O Laiyemo, Torri D Metz, Lauren Nichols, Rachel E Patzer, Anisha Sekar, Nora G Singer, Lauren E Stiles, Barbara S Taylor, Shifa Ahmed, Heather A Algren, Khamal Anglin, Lisa Aponte-Soto, Hassan Ashktorab, Ingrid V Bassett, Brahmchetna Bedi, Nahid Bhadelia, Christian Bime, Marie-Abele C Bind, Lora J Black, Andra L Blomkalns, Hassan Brim, Mario Castro, James Chan, Alexander W Charney, Benjamin K Chen, Li Qing Chen, Peter Chen, David Chestek, Lori B Chibnik, Dominic C Chow, Helen Y Chu, Rebecca G Clifton, Shelby Collins, Maged M Costantine, Sushma K Cribbs, Steven G Deeks, John D Dickinson, Sarah E Donohue, Matthew S Durstenfeld, Ivette F Emery, Kristine M Erlandson, Julio C Facelli, Rachael Farah-Abraham, Aloke V Finn, Melinda S Fischer, Valerie J Flaherman, Judes Fleurimont, Vivian Fonseca, Emily J Gallagher, Jennifer C Gander, Maria Laura Gennaro, Kelly S Gibson, Minjoung Go, Steven N Goodman, Joey P Granger, Frank L Greenway, John W Hafner, Jenny E Han, Michelle S Harkins, Kristine S P Hauser, James R Heath, Carla R Hernandez, On Ho, Matthew K Hoffman, Susan E Hoover, Carol R Horowitz, Harvey Hsu, Priscilla Y Hsue, Brenna L Hughes, Prasanna Jagannathan, Judith A James, Janice John, Sarah Jolley, S E Judd, Joy J Juskowich, Diane G Kanjilal, Elizabeth W Karlson, Stuart D Katz, J Daniel Kelly, Sara W Kelly, Arthur Y Kim, John P Kirwan, Kenneth S Knox, Andre Kumar, Michelle F Lamendola-Essel, Margaret Lanca, Joyce K Lee-Lannotti, R Craig Lefebvre, Bruce D Levy, Janet Y Lin, Brian P Logarbo, Jennifer K Logue, Michele T Longo, Carlos A Luciano, Karen Lutrick, Shahdi K Malakooti, Gail Mallett, Gabrielle Maranga, Jai G Marathe, Vincent C Marconi, Gailen D Marshall, Christopher F Martin, Jeffrey N Martin, Heidi T May, Grace A Mccomsey, Dylan Mcdonald, Hector Mendez-Figueroa, Lucio Miele, Murray A Mittleman, Sindhu Mohandas, Christian Mouchati, Janet M Mullington, Girish N Nadkarni, Erica R Nahin, Robert B Neuman, Lisa T Newman, Amber Nguyen, Janko Z Nikolich, Igho Ofotokun, Princess U Ogbogu, Anna Palatnik, Kristy T S Palomares, Tanyalak Parimon, Samuel Parry, Sairam Parthasarathy, Thomas F Patterson, Ann Pearman, Michael J Peluso, Priscilla Pemu, Christian M Pettker, Beth A Plunkett, Kristen Pogreba-Brown, Athena Poppas, J Zachary Porterfield, John G Quigley, Davin K Quinn, Hengameh Raissy, Candida J Rebello, Uma M Reddy, Rebecca Reece, Harrison T Reeder, Franz P Rischard, Johana M Rosas, Clifford J Rosen, Nadine G Rouphael, Dwight J Rouse, Adam M Ruff, Christina Saint Jean, Grecio J Sandoval, Jorge L Santana, Shannon M Schlater, Frank C Sciurba, Caitlin Selvaggi, Sudha Seshadri, Howard D Sesso, Dimpy P Shah, Eyal Shemesh, Zaki A Sherif, Daniel J Shinnick, Hyagriv N Simhan, Upinder Singh, Amber Sowles, Vignesh Subbian, Jun Sun, Mehul S Suthar, Larissa J Teunis, John M Thorp, Amberly Ticotsky, Alan T N Tita, Robin Tragus, Katherine R Tuttle, Alfredo E Urdaneta, P J Utz, Timothy M Vanwagoner, Andrew Vasey, Suzanne D Vernon, Crystal Vidal, Tiffany Walker, Honorine D Ward, David E Warren, Ryan M Weeks, Steven J Weiner, Jordan C Weyer, Jennifer L Wheeler, Sidney W Whiteheart, Zanthia Wiley, Natasha J Williams, Juan P Wisnivesky, John C Wood, Lynn M Yee, Natalie M Young, Sokratis N Zisis, Andrea S Foulkes

Pediatrics Research and Scholarship

IMPORTANCE: SARS-CoV-2 infection can result in ongoing, relapsing, or new symptoms or other health effects after the acute phase of infection; termed post-acute sequelae of SARS-CoV-2 infection (PASC), or long COVID. The characteristics, prevalence, trajectory and mechanisms of PASC are ill-defined. The objectives of the Researching COVID to Enhance Recovery (RECOVER) Multi-site Observational Study of PASC in Adults (RECOVER-Adult) are to: (1) characterize PASC prevalence; (2) characterize the symptoms, organ dysfunction, natural history, and distinct phenotypes of PASC; (3) identify demographic, social and clinical risk factors for PASC onset and recovery; and (4) define the biological mechanisms underlying PASC pathogenesis. …

2023 Annual Campus Security And Fire Safety Report, University Of Nebraska-Lincoln, University Police, University Of Nebraska-Lincoln

University of Nebraska-Lincoln, University Police

2023 Annual Campus Security and Fire Safety Report, University of Nebraska-Lincoln

Safety and security information for the University of Nebraska-Lincoln, including crime and fire statistics for the 2022 calendar year, and the information required by the Drug-Free Schools and Communities Act of 1989. All data are submitted to the United States Department of Education according to law.

A Multifaceted Approach Using Implementation Science Methods To Increase Chg Bathing Compliance And Reduce Central Line Associated Blood Stream Infections On A Non-Icu Unit, Emily E. Warwick

VCU Health Nursing

BACKGROUND or RATIONALE:

The Acute Care Surgery unit (ACS) is a General and Progressive level of care post-operative unit at VCU Health system. Between quarter four 2021 and quarter one of 2023, five Central line associated blood stream infections (CLABSIs) occurred. NDNQI data revealed ACS had a higher CLABSI rate per 1,000 patient days than the national average of other similar type units in other magnet hospitals.

STATEMENT OF THE PROBLEM:

A GAP analysis revealed ACS did not achieve the 80% CHG compliance goal set by VCU Health’s Infection Prevention Department in all six quarters that these five CLABSIs occurred. …

Oncolytic Virus-Based Suicide Gene Therapy For Cancer Treatment: A Perspective Of The Clinical Trials Conducted At Henry Ford Health, Shivani Thoidingjam, Sushmitha Sriramulu, Svend Freytag, Stephen L. Brown, Jae Ho Kim, Indrin J. Chetty, Farzan Siddiqui, Benjamin Movsas, Shyam Nyati

Radiation Oncology Articles

Gene therapy manipulates or modifies a gene that provides a new cellular function to treat or correct a pathological condition, such as cancer. The approach of using gene manipulation to modify patient's cells to improve cancer therapy and potentially find a cure is gaining popularity. Currently, there are 12 gene therapy products approved by US-FDA, EMA and CFDA for cancer management, these include Rexin-G, Gendicine, Oncorine, Provange among other. The Radiation Biology Research group at Henry Ford Health has been actively developing gene therapy approaches for improving clinical outcome in cancer patients. The team was the first to test a …

The Covid-19 Pandemic As A Catalyst For Integrated Global Mental Healthcare And Tuberculosis Care, Alexander L. Chu, Aneeta Pasha, Carmen Contreras, Leonid Lecca, Annika C. Sweetland, Jerome T. Galea

Social Work Faculty Publications

Mental disorders are common among persons with tuberculosis (TB), and the COVID-19 pandemic has only amplified the mental and physical health consequences of this deadly synergy. Here, we call to attention the immense vulnerability of people with TB to mental disorders during the pandemic and highlight the unique challenges and opportunities that the pandemic brings to the future integration of global TB and mental healthcare. We argue that the pandemic era is an ideal period to accelerate this integration and we provide research and policy recommendations to actualise this urgent need.

Postgraduate Residency Program: Pedagogical Strategies In Bridging The Transition From Novice Nurse Practitioner To Confident Primary Care Provider, Kelly Stauter, Katherine Bydalek

CoTL 2023 Research Talks

Advancing the education of new nurse practitioners helps close the gap with the knowledge and core competencies necessary to practice independently and master delivery of quality care across the life span to vulnerable populations. Innovative teaching strategies incorporate the needs of the novice nurse practitioner and are designed to support the inclusive learning environment through educational technology, learner-centered activities, interprofessional partnerships, and local community-based agencies that facilitate active learning. Expanding the didactic and clinical training experience by integrating specialty rotations and simulation immersive events, enhances learning outside of the classroom and equips the postgraduate nurse practitioner with the skills and …

Deadly Disease And The Collective Adoption Of International Environmental Agreements, Vivian Ike

International Relations - All Scholarship

No abstract provided.

Undergraduate Review, Vol. 17, 2022/2023

Undergraduate Review

No abstract provided.

Location Report 2023, The Office Of Program Evaluation, Education And Research At The Unm School Of Medicine

University of New Mexico School of Medicine Location Report

No abstract provided.

University Of New Mexico Health Sciences Center Discovery Research Annual Report 2023, Michael Haederle, Claire Hannon, Elizabeth Dwyer Sandlin, Nicole San Roman, Chris Ramirez, Brianna Wilson, Jett Loe, Sara Mota, Sarah Head

Research Annual Reports

Research annual report from the University of New Mexico Health Sciences Center.

Sexually Transmitted Infection (Sti), Children's Mercy Kansas City

Clinical Pathways (Formally Known As Clinical Practice Guidelines)

No abstract provided.

Graduate Medical Education Annual Report 2022-2023, Children's Mercy Kansas City

GME Annual Reports

Annual report of the Children's Mercy Hospital Graduate Medical Education department, including pediatric residency, internal medicine/pediatrics residency, fellowship programs, medical students, continuing medical education, and library services.

Contraception And Healthcare Utilization By Reproductive-Age Women Who Use Drugs In Rural Communities: A Cross-Sectional Survey., Ximena A. Levander, Canyon A. Foot, Sara L. Magnusson, Ryan R. Cook, Jerel M. Ezell, Judith Feinberg, Vivian F. Go, Kathryn E. Lancaster, Elizabeth Salisbury-Afshar, Gordon S. Smith, Ryan P. Westergaard, April M. Young, Judith I. Tsui, P. Todd Korthuis

Epidemiology and Environmental Health Faculty Publications

BACKGROUND: Women who use drugs (WWUD) have low rates of contraceptive use and high rates of unintended pregnancy. Drug use is common among women in rural U.S. communities, with limited data on how they utilize reproductive, substance use disorder (SUD), and healthcare services.

OBJECTIVE: We determined contraceptive use prevalence among WWUD in rural communities then compared estimates to women from similar rural areas. We investigated characteristics of those using contraceptives, and associations between contraceptive use and SUD treatment, healthcare utilization, and substance use.

DESIGN: Rural Opioids Initiative (ROI) - cross-sectional survey using respondent-driven sampling (RDS) involving eight rural U.S. regions …