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Ramer High School Announcement, 1917

Documents

Announcement for the 1917-1918 school year of Ramer High School, McNairy County, Tennessee.

Ramer High School Announcement, 1919

Documents

Announcement for the 1919-1920 school year of Ramer High School, McNairy County, Tennessee.

Opportunities, Barriers, And Recommendations In Down Syndrome Research., James A. Hendrix, Angelika Amon, Leonard Abbeduto, Stamatis Agiovlasitis, Tarek Alsaied, Heather A. Anderson, Lisa J. Bain, Nicole Baumer, Anita Bhattacharyya, Dusan Bogunovic, Kelly N. Botteron, George Capone, Priya Chandan, Isabelle Chase, Brian Chicoine, Cécile Cieuta-Walti, Lara R. Deruisseau, Sophie Durand, Anna Esbensen, Juan Fortea, Sandra Giménez, Ann-Charlotte Granholm, Laura J. Hahn, Elizabeth Head, Hampus Hillerstrom, Lisa M. Jacola, Matthew P. Janicki, Joan M. Jasien, Angela R. Kamer, Raymond D. Kent, Bernard Khor, Jeanne B. Lawrence, Catherine Lemonnier, Amy Feldman Lewanda, William Mobley, Paul E. Moore, Linda Pollak Nelson, Nicolas M. Oreskovic, Ricardo S. Osorio, David Patterson, Sonja A. Rasmussen, Roger H. Reeves, Nancy Roizen, Stephanie Santoro, Stephanie L. Sherman, Nasreen Talib, Ignacio E. Tapia, Kyle M. Walsh, Steven F. Warren, A Nicole White, Guang William Wong, John S. Yi

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Recent advances in medical care have increased life expectancy and improved the quality of life for people with Down syndrome (DS). These advances are the result of both pre-clinical and clinical research but much about DS is still poorly understood. In 2020, the NIH announced their plan to update their DS research plan and requested input from the scientific and advocacy community.

OBJECTIVE: The National Down Syndrome Society (NDSS) and the LuMind IDSC Foundation worked together with scientific and medical experts to develop recommendations for the NIH research plan.

METHODS: NDSS and LuMind IDSC assembled over 50 experts across …

Ss-Phenylethylamine: A Novel Chemo-Attractant Agent, August Henry Burg

Microbiological Sciences

Bacterial metabolism and physiology are finely tuned mechanisms that maintain homeostasis for the bacterium and allow for responses to environmental signals. Responses could include anything from regulation of cell division to the expression of virulence factors leading to serious infection. This thesis explores the role of neurotransmitter molecules and ß-phenylethylamine (a structurally similar molecule to catecholamines) on the physiological characteristics of flhD expression, biofilm formation, and chemotactic behaviors in the E. coli organism. We observed changes in physiology leading to chemotactic changes in the presence of ß-phenylethylamine through the Plug Agarose Assay as well as the Microfluidic Assay. In a …

Matters Of Biocybersecurity With Consideration To Propaganda Outlets And Biological Agents, Xavier-Lewis Palmer, Ernestine Powell, Lucas Potter, Thaddeus Eze (Ed.), Lee Speakman (Ed.), Cyril Onwubiko (Ed.)

Electrical & Computer Engineering Faculty Publications

The modern era holds vast modalities in human data utilization. Within Biocybersecurity (BCS), categories of biological information, especially medical information transmitted online, can be viewed as pathways to destabilize organizations. Therefore, analysis of how the public, along with medical providers, process such data, and the methods by which false information, particularly propaganda, can be used to upset the flow of verified information to populations of medical professionals, is important for maintenance of public health. Herein, we discuss some interplay of BCS within the scope of propaganda and considerations for navigating the field.

Effects Of Hiv-1 Gp120 On Intracellular Levels Of Iron And Reactive Oxygen Species: Implications For Lysosomal Stress, Koffi L. Lakpa

Theses and Dissertations

Approximately 1.2 million people in the U.S.A are living with HIV-1. The development of antiretroviral therapeutics has increased the life expectancy of people living with HIV-1 (PLWH). Yet, there is a growing concern for aging HIV-positive individuals because about 50% of PLWH develop neurological impairments, termed HIV-associated neurocognitive disorders (HAND). There are no treatments for HAND and the mechanisms underlying its pathogenesis remain unclear. Several factors are implicated in HAND pathogenesis, such as HIV-1 coat protein gp120, endolysosome and mitochondrial dysfunction, and elevated levels of reactive oxygen species (ROS). Endolysosomes are acidic organelles that contain readily releasable stores of cations, …

Risk Factors For Gut Dysbiosis In Early Life, Kimberley Parkin, Claus T. Christophersen, Valerie Verhasselt, Matthew N. Cooper, David Martino

Research outputs 2014 to 2021

Dysbiosis refers to a reduction in microbial diversity, combined with a loss of beneficial taxa, and an increase in pathogenic microorganisms. Dysbiosis of the intestinal microbiota can have a substantial effect on the nervous and immune systems, contributing to the onset of several inflammatory diseases. Epidemiological studies provided insight in how changes in the living environment have contributed to an overall loss of diversity and key taxa in the gut microbiome, coinciding with increased reports of atopy and allergic diseases. The gut microbiome begins development at birth, with major transition periods occurring around the commencement of breastfeeding, and the introduction …

Observation Instrument For Student Social Attitude In Primary Schools: Validity And Reliability, Ari Setiawan, Widowati Pusporini, Hanandyo Dardjito

Jurnal Penelitian dan Evaluasi Pendidikan

This study aims to (1) identify the content validity of observations of students' social attitudes, (2) identify the construct validity of the observation instruments of students 'social attitudes, and (3) identify the reliability of observations of students' social attitudes. The subjects of this study were grades IV and V of elementary school students in Yogyakarta province selected using cluster random sampling. Observation guidelines were used to collect the data using a summative rating scale model. The content validity was analyzed by applying Aiken assisted by Microsoft Excel, the construct validity by using second-order Confirmatory Factor Analysis assisted by Lisrel, and …

Pengaruh Cold Water Immersion Terhadap Laktat, Nyeri Otot, Fleksibilitas Dan Tingkat Stres Pasca Latihan Intensitas Sub Maksimal, Moh Nanang Himawan Kusuma, Muh. Syafei, Saryono Saryono, Wildan Qohhar

Jurnal Keolahragaan

Weight Training adalah metode latihan untuk meningkatkan kekuatan dan kinerja neuromuskular melalui proses hyperthropy, namun juga meningkatkan produksi Laktat, menyebabkan inflamasi otot, meng-gangu metabolisme tubuh sehingga menurunkan performa. Stimulus dingin pada Cold water Immersion dapat mengurangi laju metabolisme, menyerap suhu jaringan lokal, menurunkan kepekaan saraf dan mengu-rangi rasa nyeri sehingga menurunkan resiko terjadinya cidera musculoskeletal dan kelainan metabolisme. Penelitian ini bertujuan untuk menguji pengaruh cold water Immersion 5°C (CWI5°C) terhadap Laktat pada darah, nyeri otot, fleksibilitas dan tingkat stress pasca latihan berbeban intensitas sub maksimal. Pre- dan Post-test dalam penelitian ini menggunakan kelompok kontrol dengan pendekatan cross sectional. Sebanyak 15 …

The Effect Of Citrulline Supplementation On Lactic Acid Blood Level And Oxygen Saturation (Sao2) In Submaximal Physical Activity, Ibrah Fastabiqi, Elyana Asnar, Harlina Harlina

Folia Medica Indonesiana

An achievement in sport is one of the benchmarks of success of every athlete. One of the causes of the performance degradation is fatigue due to the formation of lactic acid. Supplements are proved to improve the performance in athletes. The purpose of this study was to determine the effect of citrulline supplementation on lactic acid levels and oxygen saturation on submaximal physical activity. Fatigue can be seen from lactic acid levels in subjects who have performed physical activity. This research method used randomized group pretest postest group design. The subjects used were male students of pencak silat airlangga university, …

Optimal Adjustment Of The Human Circadian Clock In The Real World, Samuel Christensen, Yitong Huang, Olivia J. Walch, Daniel B. Forger

Mathematics Sciences: Faculty Publications

Which suggestions for behavioral modifications, based on mathematical models, are most likely to be followed in the real world? We address this question in the context of human circadian rhythms. Jet lag is a consequence of the misalignment of the body’s internal circadian (~24-hour) clock during an adjustment to a new schedule. Light is the clock’s primary synchronizer. Previous research has used mathematical models to compute light schedules that shift the circadian clock to a new time zone as quickly as possible. How users adjust their behavior when provided with these optimal schedules remains an open question. Here, we report …

Modeling By Disruption And A Selected-For Partner For The Nude Locus, Jian Li, Yun-Kyoung Lee, Wenyu Fu, Anne M. Whalen, Mario C. Estable, Laurel A. Raftery, Kristin White, Lorin Weiner, Janice L. Brissette

Life Sciences Faculty Research

A long‐standing problem in biology is how to dissect traits for which no tractable model exists. Here, we screen for genes like the nude locus (Foxn1)—genes central to mammalian hair and thymus development—using animals that never evolved hair, thymi, or Foxn1. Fruit flies are morphologically disrupted by the FOXN1 transcription factor and rescued by weak reductions in fly gene function, revealing molecules that potently synergize with FOXN1 to effect dramatic, chaotic change. Strong synergy/effectivity in flies is expected to reflect strong selection/functionality (purpose) in mammals; the more disruptive a molecular interaction is in alien contexts (flies), the more beneficial it …

Models And Methods Of Designing Human-Machine Interaction-Oriented Interfaces, Ozod Radjabov, Shakhrillo Bobokulov, Behruz Boboqulov, Hojiyev Sunatullo

Bulletin of TUIT: Management and Communication Technologies

Formalization approaches of user interface design (UID) in conjunction with model driven techniques aim to improve the usability in terms of conformity to standards or style guides and to leverage code generation of interactive software systems, so that various UI platforms for web, desktop or mobile Applications are supported. Because large parts of the UI are described platform independent instead of platform dependent implementations, re-usability of the UI concept is also improved. However, UI formalization requires the usage of a formal UI description language and a higher level of abstractness compared to concrete UI code. These languages need to be …

Evaluating Instructional Designs With Mental Workload Assessments In University Classrooms, Luca Longo, Giuliano Orru'

Articles

Cognitive cognitive load theory (CLT) has been conceived for improving instructional design practices. Although researched for many years, one open problem is a clear definition of its cognitive load types and their aggregation towards an index of overall cognitive load. In Ergonomics, the situation is different with plenty of research devoted to the development of robust constructs of mental workload (MWL). By drawing a parallel between CLT and MWL, as well as by integrating relevant theories and measurement techniques from these two fields, this paper is aimed at investigating the reliability, validity and sensitivity of three existing self-reporting mental workload …

Cardiac Organoid Technology And Computational Processing Of Cardiac Physiology For Advanced Drug Screening Applications, Plansky Hoang

Dissertations - ALL

Stem cell technology has gained considerable recognition since its inception to advance disease modeling and drug screening. This is especially true for tissues that are difficult to study due to tissue sensitivity and limited regenerative capacity, such as the heart. Previous work in stem cell-derived cardiac tissue has exploited how we can engineer biologically functional heart tissue by providing the appropriate external stimuli to facilitate tissue development. The goal of this dissertation is to explore the potentials of stem cell cardiac organoid models to recapitulate heart development and implement analytical computational tools to study cardiac physiology. These new tools were …

Questions Of Temporary Adaptation Of Weightlifters To Different Climatic And Geographical Conditions, Rashid Matkarimov

Eurasian Journal of Sport Science

Aim: to study the features of adaptive adjustment of the body of weightlifters in various geographical climate conditions and the influence of training factors, physiotherapeutic agents and adaptogens of plant origin on these processes. Method of research: Analysis and generalization of scientific and methodological literature, questionnaires, instrumental method, pedagogical testing and observation, pedagogical experiment, statistical methods of results processing. Results: Training loads before and after the migration period of training are experimentally justified, and the most effective options are considered in combination with the use of plant-based adaptogens that contribute to the active course of adaptation processes and maintain a …

The Afit Engineer, Volume 2, Issue 4, Graduate School Of Engineering And Management, Air Force Institute Of Technology

AFIT Documents

In this issue:

• AFMC Spark Tank Semi-finalist
• New AFIT Patents
• 2020 Graduate School Award Winners
• Airmen and Artificial Intelligence
• Nuclear Treaty Monitoring

Body Composition In Elite Strongman Competitors, William J. Kraemer, Lydia K. Caldwell, Emily M. Post, William H. Dupont, Emily R. Martini, Nicholas A. Ratamess, Tunde K. Szivak, Jason P. Shurley, Matthew K. Beeler, Jeff S. Volek, Carl M. Maresh, Janice S. Todd, Bryant J. Walrod, Parker N. Hyde, Ciaran Fairman, Thomas M. Best

Health and Sport Sciences Faculty Scholarship

Kraemer, WJ, Caldwell, LK, Post, EM, DuPont, WH, Martini, ER, Ratamess, NA, Szivak, TK, Shurley, JP, Beeler, MK, Volek, JS, Maresh, CM, Todd, JS, Walrod, BJ, Hyde, PN, Fairman, C, and Best, TM. Body composition in elite strongman competitors. J Strength Cond Res 34(12): 3326–3330, 2020—The purpose of this descriptive investigation was to characterize a group of elite strongman competitors to document the body composition of this unique population of strength athletes. Data were collected from eligible competitors as part of a health screening program conducted over 5 consecutive years. Imaging was acquired using dual-energy x-ray absorptiometry (DXA), providing total …

Chronic Pain Treatment Strategies In Parkinson’S Disease, Amber N. Edinoff, Niro Sathivadivel, Timothy Mcbride, Allyson Parker, Chikezie Okeagu, Alan David Kaye, Adam M. Kaye, Jessica S. Kaye, Rachel J. Kaye, Meeta M. Sheth, Omar Viswanath, Ivan Urits

School of Pharmacy Faculty Articles

Neurological disorders, including Parkinson’s disease (PD), have increased in prevalence and are expected to further increase in the coming decades. In this regard, PD affects around 3% of the population by age 65 and up to 5% of people over the age of 85. PD is a widely described, physically and mentally disabling neurodegenerative disorder. One symptom often poorly recognized and under-treated by health care providers despite being reported as the most common non-motor symptom is the finding of chronic pain. Compared to the general population of similar age, PD patients suffer from a significantly higher level and prevalence of …

Hormonal Responses To Seasonal Thermal And Ecological Stressors In Japanese Macaques (Macaca Fuscata), Lilianne Nelson

Masters Theses

Relative to most primate species, Japanese macaques (Macaca fuscata) experience extreme seasonal variation in thermal and ecological stressors that can impact energetic demands. To cope with these environmental changes, levels of metabolic hormones, such as cortisol and triiodothyronine, fluctuate to facilitate energetic adjustments. While previous research in primates has investigated thermal and ecological stressors individually, a combined assessment of these stressors alongside hormone levels can provide a more holistic understanding of the relationship between a primate’s thermoregulation, energetic balance, and stress. The goals of this study were to determine the effects of season, temperature and ecological stress on …

On The Straight And Narrow: How Cultural Beliefs About Sex/Gender Manifest In College Biology Learning Environments., Katherine Ray Kng

Electronic Theses and Dissertations

This dissertation focused on the ways that social beliefs about sex/gender and sexuality manifest in biology classrooms. Especially for health science students, classes include topics like sex, sexuality, sexual behaviors, or sex determination that forms the foundation of their understanding of human forms and behaviors. If the information they receive does not include the LGBTQIA+ community, their education will fail to adequately prepare them for the reality of healthcare practice where they will be expected to treat all patients with dignity and respect. There are three chapters in this dissertation. In chapter one, I asked what beliefs about and conceptions …

The 2019 P-Mig Student Survey Report And Capturing The Undergraduate Perspective Of Physiology Programming, Jennifer Rogers, Jenny L. Mcfarland, Claudia I. Stanescu, Patrick L. Crosswhite, Anne R. Crecelius

Health and Sport Science Faculty Publications

The aim of the 2019 Student Survey was to inform the Physiology Majors Interest Group (PMIG) of characteristics of undergraduates enrolled in physiology courses or degree programs from across the United States, to be used as one input source for development of program-level guidelines. 1389 participants from seven universities completed the 2019 P-MIG Student Survey. 37% reported enrollment in a physiology/human physiology major; allied health related programs were the second most common (24%). 61% of respondents reported attending a community college, the majority of whom enrolled in one or more courses at a community college while in high school (44%). …

Spot The Difference: Comparing Results Of Analyses From Real Patient Data And Synthetic Derivatives, Randi E Foraker, Sean C Yu, Aditi Gupta, Andrew P Michelson, Jose A Pineda Soto, Ryan Colvin, Francis Loh, Marin H Kollef, Thomas Maddox, Bradley Evanoff, Hovav Dror, Noa Zamstein, Albert M Lai, Philip R O Payne

2020-Current year OA Pubs

BACKGROUND: Synthetic data may provide a solution to researchers who wish to generate and share data in support of precision healthcare. Recent advances in data synthesis enable the creation and analysis of synthetic derivatives as if they were the original data; this process has significant advantages over data deidentification.

OBJECTIVES: To assess a big-data platform with data-synthesizing capabilities (MDClone Ltd., Beer Sheva, Israel) for its ability to produce data that can be used for research purposes while obviating privacy and confidentiality concerns.

METHODS: We explored three use cases and tested the robustness of synthetic data by comparing the results of …

Association Between Social Media Exposure To Food And Beverages With Nutrient Intake Of Female Adolescents, Cholida Adiba, Siti Fatimah Pradigdo, Martha Irene Kartasurya

Kesmas

Communication technology development has influenced adolescent food choices and intakes. This study aimed to investigate the association between social media exposure to food and beverage content and nutrient intake among female adolescents. The study was conducted in a cross-sectional design. The targeted population was 104 female students aged 14–18 years old at 'XY' High School in Semarang, Central Java, Indonesia. Eighty-one subjects were chosen by clustered random sampling. Data were collected by interviews using structured questionnaires and a 3x24-hour recall method. Data analyses were conducted by chi-square, Fisher exact tests, and logistic regression. The median and standard deviations of social-media, …

The Relationship Between Brain Dominance And Lateral Preference Among Physical Education Students At Kadoorie University, Ali Qadoumi, Moatasem Abo-Alia, Mohammad Qadoumi, Hamed Salameh

An-Najah University Journal for Research - B (Humanities)

The purpose of this study was to identify the common brain dominance (BD) and lateral preference (LP) among physical education students at Kadoorieuniversity and determine the relationship between (BD) and (LP), in addition to determine the differences in (BD)patternand (LP)according to gender and academic specialization variables. To achieve that the study was conducted on a random sample that consisted of (112) maleand female students. to gather data, the researchers used (Diane, 2005) scalefor measuring (BD)and (Kashihara, 1979)scale for measuring (LP).The results revealed that the common pattern of (BD) for the students was integrated brain hemisphere dominance and their pattern of …

The Effect Of Repetition Of Three Types Of Kata On The Response Of Selected Hormones, Enzymes, Blood Contents, And Cardiovascular System Among Karate Players Aged 15-25 Years, Abdel Naser Qadumi, Mersal Mersal

An-Najah University Journal for Research - B (Humanities)

The purpose of this study was to investigate the effect of repetition of threetypes of kata on the response of selectedhormones, enzymes,among karate players aged15-25 years. The purposive sample consisted of (30) players from various sports clubs and karate centers in the northern West Bank (Nablus, Tulkarem, Jenin, Qalqilya) and holding a black belt and above. The means of (age, height, weight, and body mass index) were respectively (17.13 yr, 171.77 cm, 62.47 kg, and 21.04 kg/m²). The study sample was divided into threegroups of (10) players in each group, the first group do Tekki Shodan Kata, the second group …

Role For Carbohydrate Response Element-Binding Protein (Chrebp) In High Glucose-Mediated Repression Of Long Noncoding Rna Tug1, Jianyin Long, Daniel L Galvan, Koki Mise, Yashpal S Kanwar, Li Li, Naravat Poungavrin, Paul A Overbeek, Benny H Chang, Farhad R Danesh

Faculty, Staff and Students Publications

Long noncoding RNAs (lncRNAs) have been shown to play key roles in a variety of biological activities of the cell. However, less is known about how lncRNAs respond to environmental cues and what transcriptional mechanisms regulate their expression. Studies from our laboratory have shown that the lncRNA Tug1 (taurine upregulated gene 1) is crucial for the progression of diabetic kidney disease, a major microvascular complication of diabetes. Using a combination of proximity labeling with the engineered soybean ascorbate peroxidase (APEX2), ChIP-qPCR, biotin-labeled oligonucleotide pulldown, and classical promoter luciferase assays in kidney podocytes, we extend our initial observations in the current …

Quantifying The Impact Of Chronic Stress On Racial Disparities In Cardiovascular Disease, Nnadozie Emechebe

USF Tampa Graduate Theses and Dissertations

Background: Despite declining mortality in cardiovascular diseases (CVD), racial disparities between non-Hispanic Blacks (NHB) and to non-Hispanic Whites (NHW) persist. Although the prevalence of traditional risk factors of CVD such as hypertension, is higher in NHB compared to NHW, adjusting for this difference does not eliminate the disparity completely. This suggests other factors might explain the persisting disparities. Thus, the purpose of this dissertation is to quantify the impact of chronic stress in explaining the racial disparities in cardiovascular diseases (CVD). This dissertation contains three studies that addressed the following Specific Aims: Specific aims: 1) To create and assess the …

Chronic Pain Treatment Strategies In Parkinson’S Disease, Amber Edinoff, Niro Sathivadivel, Timothy Mcbride, Allyson Parker, Chikezie Okeagu, Alan D. Kaye, Adam M. Kaye, Jessica S. Kaye, Rachel J. Kaye, Meeta M. Sheth, Omar Viswanath, Ivan Urits

School of Medicine Faculty Publications

Neurological disorders, including Parkinson's disease (PD), have increased in prevalence and are expected to further increase in the coming decades. In this regard, PD affects around 3% of the population by age 65 and up to 5% of people over the age of 85. PD is a widely described, physically and mentally disabling neurodegenerative disorder. One symptom often poorly recognized and under-treated by health care providers despite being reported as the most common non-motor symptom is the finding of chronic pain. Compared to the general population of similar age, PD patients suffer from a significantly higher level and prevalence of …

Moonshots For Aging, Sandeep Kumar, Timothy R Peterson

Open Access Publications

As the global population ages, there is increased interest in living longer and improving one's quality of life in later years. However, studying aging - the decline in body function - is expensive and time-consuming. And despite research success to make model organisms live longer, there still aren't really any feasible solutions for delaying aging in humans. With space travel, scientists and engineers couldn't know what it would take to get to the moon. They had to extrapolate from theory and shorter-range tests. Perhaps with aging, we need a similar moonshot philosophy. And though "shot" might imply medicine, perhaps we …