Digital Commons Network^™

Miraculous Monstrosity: Birth And Female Sexuality In The Illuminated Scivias And Cloisters Apocalypse, Jenna M. Mckellips

Medieval Feminist Forum: A Journal of Gender and Sexuality

This paper compares the illuminations in two medieval apocalypses, the Cloisters Apocalypse and Hildegard von Bingen’s Scivias, to inspect their similar constructions of female sexuality, motherhood, and monstrosity. It first analyzes the monstrosity of female sexual organs found in Hildegard’s portrayal of the Church and the Mother of the Antichrist. The paper then goes on to consider the uncanny slippage between images of birth and death in the Cloisters’s depiction of John and the Woman of Revelation 12. Ultimately, the paper not only explores the monstrosity of female bodies in apocalyptic manuscripts, but also concludes that medieval women’s …

Characteristics Of Physiology And Physiology-Related Pre-Health Degree Programs In The Physiology Majors Interest Group, Yvonne Ogrodzinski, Erica A. Wehrwein, Kevin Kelly, James M. Poteracki, Valerie Vanryn, Anne R. Crecelius

Health and Sport Science Faculty Publications

The Physiology Majors Interest Group (P-MIG), a grassroots organization of educators, has collected data on the history and characteristics of Physiology and highly related undergraduate programs (ex: Human Biology, Pre-Medicine, Biomedical Sciences, etc.) that serve a common population of prehealth students. Data was obtained as part of an online survey sent out to P-MIG conference attendees at the 2017-2019 annual meetings (n=30). Participating institutions indicate that 25.9% have degrees called Physiology aligned with 28% being housed in a department of physiology, 75.9% are a Bachelor of Science program, 34.9% are affiliated with a College of Arts and Sciences, and 80% …

Studying The Efficacy Of An Injectable 3-Dimensional Fibrin Extracellular Matrix To Characterize The Effects Of Antitumor Agents On Sw620 Cells In A Microfluidic Device, Thèo Anastos

Master's Theses

Colorectal cancer is the third most common cancer in the United States and there is currently a lot of research going into new antitumor agents to kill the cancer. One method for replicating the tumor response to a drug in vivo is by creating an in vitro drug testing model to replicate the in vivo condition. This research project was conducted to determine the efficacy of testing tumor cultures in a microfluidic device as a way to provide accurate drug responses in vitro instead of using in vivo subjects in clinical trials. A total of four experiments were conducted with …

Biological Semantic Segmentation On Ct Medical Images For Kidney Tumor Detection Using Nnu-Net Framework, Andres Bergsneider

Master's Theses

Healthcare systems are constantly challenged with bottlenecks due to human-reliant operations, such as analyzing medical images. High precision and repeatability is necessary when performing a diagnostics on patients with tumors. Throughout the years an increasing number of advancements have been made using various machine learning algorithms for the detection of tumors helping to fast track diagnosis and treatment decisions. “Black Box” systems such as the complex deep learning networks discussed in this paper rely heavily on hyperparameter optimization in order to obtain the most ideal performance. This requires a significant time investment in the tuning of such networks to acquire …

Costs And Benefits Of Physical Therapy Program Implementation For Air Force Fighter Pilots, Christian G. Erneston

Theses and Dissertations

Air Force fighter pilots face risks associated with neck and spine injuries sustained while operating fighter aircraft. Studies from the flying and medical communities indicate that muscle-strengthening prehabilitative care may decrease the risk of flying related injuries in high performance aircraft pilots. For this reason, the U.S. Air Force provided $24.9M to implement the Optimizing the Human Weapon System (OHWS) program. The program provides physical therapy and strength training to fighter pilots in participating units at twenty-one Air Force bases with the intent of reducing injury rates and time out of the cockpit. From a healthcare perspective there is interest …

Lunar/Mars Exploration (Moderator: Mark Kirasich, Gateway/Hls/Ltv), Kathy Lueders, Joel Kearns, Eric Ianson, Sean Mahoney, Ian Fichtenbaum

Spaceport Summit

No abstract provided.

Ar-Based Simulation Interaction And Human Factor Assessment For Human Robot Cooperation Assembly Planning, Wang Qiang, Xiumin Fan, Qichang He, Wenmin Zhu

Journal of System Simulation

Abstract: To improve assembly efficiency, it has become a trend for traditional manual assembly workstations to be carried out human-robot collaboration transformation. To realize the safe and fast evaluation of the improvement scheme, a general human-robot collaboration simulation method and human factor evaluation method based on Augmented Reality are proposed. Four levels of human-robot collaboration assembly simulation are established. An interactive scheme between real human and virtual robot for visual detection, perception and feedback is established. A fuzzy comprehensive evaluation model of human physiological and psychological indicators for workstation design is constructed. The prototype system is developed. Taking the assembly …

Effects Of Drying, Packaging Conditions And Storage Time On Proximate Composition Of Chia Seeds (Salvia Hispanica), Ashura Katunzi-Kilewela, Leonard Rweyemamu, Oscar Kibazohi, Lilian Kaale

Tanzania Journal of Science

The effects of drying, packaging conditions and storage time on proximate composition of chia seeds were investigated. Chia seeds were dried at 63 °C for 30 min (low-temperature long time–LTLT) and at 75 °C for 30 s (high-temperature short time-HTST) using dry oven, air/vacuum-packed and stored for ten weeks. The effect of heat processing (drying) on chia seeds had significant difference (p < 0.05) in ash, fiber and fat contents while there was no significant difference (p > 0.05) in moisture and protein contents. Except for fiber content, there was no significant difference (p > 0.05) in moisture, ash, fat and protein of chia seeds dried at LTLT and HTST before storage. During storage time, there was …

Establishing A Mechanistic Link Between Disturbed Flow And Aneurysm Formation In A 3d Cerebral Bifurcation Model, Nesrine Bouhrira

Theses and Dissertations

The effect of disturbed flow profiles on the endothelium have been studied extensively in systemic vasculature, but less is known about the response of the blood-brain barrier (BBB) to these flow regimes. Here we investigate the effect of steady and pulsatile disturbed flow on the integrity of the BBB using a three-dimensional, perfusable bifurcation model consisting of a co-culture of endothelial cells with mural and glial cells. Experimental flow patterns predicted by computational fluid dynamics mimic in vivo flow regimes, specifically the presence of a recirculation zone immediately downstream of the bifurcation reveal periodic changes in the instantaneous shear stress …

Aacp Basic Resources For Pharmacy Education, Jason Guy, Ivan Portillo, Robert D. Beckett, Kayce Gill, Kimberly Mitchell, Jill Nissen, Priya Shenoy

Library Association/Organization Work

"The AACP Basic Resources for Pharmacy Education is produced as a guide for those developing or maintaining the library collections that serve colleges and schools of pharmacy. The goal of the Basic Resources list is to make recommendations of books and other works to be included in pharmacy libraries, but not all titles are required to be purchased. Each pharmacy college has its own mission and its own program(s), and so each college’s library collection must reflect that mission and support the college’s program(s). Excellent library collections are built by knowledgeable librarians and drug information specialists using their professional judgment …

Applying Spatial Video Geonarratives And Physiological Measurements To Explore Perceived Safety In Baton Rouge, Louisiana, Alina Ristea, Michael Leitner, Bernd Resch, Judith Stratmann

Faculty Publications

Spatial crime analysis, together with perceived (crime) safety analysis have tremendously benefitted from Geographic Information Science (GISc) and the application of geospatial technology. This research study discusses a novel methodological approach to document the use of emerg-ing geospatial technologies to explore perceived urban safety from the lenses of fear of crime or crime perception in the city of Baton Rouge, USA. The mixed techniques include a survey, spatial video geonarrative (SVG) in the field with study participants, and the extraction of moments of stress (MOS) from biosensing wristbands. This study enrolled 46 participants who completed geonarratives and MOS detection. A …

A Timely Call To Arms: Covid-19, The Circadian Clock, And Critical Care, Jeffrey Haspel, Minjee Kim, Phyllis Zee, Tanja Schwarzmeier, Sara Montagnese, Satchidananda Panda, Adriana Albani, Martha Merrow

2020-Current year OA Pubs

We currently find ourselves in the midst of a global coronavirus disease 2019 (COVID-19) pandemic, caused by the highly infectious novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we discuss aspects of SARS-CoV-2 biology and pathology and how these might interact with the circadian clock of the host. We further focus on the severe manifestation of the illness, leading to hospitalization in an intensive care unit. The most common severe complications of COVID-19 relate to clock-regulated human physiology. We speculate on how the pandemic might be used to gain insights on the circadian clock but, more importantly, on …

Ground Reaction Forces And Temporal Characteristics Define Cutting Performance, Matthew L. Welinski, Lindsey N. Lee, Blake Mcbroom, Bassel Mufarreh, Lex Gidley

International Journal of Exercise Science

International Journal of Exercise Science 14(1): 211-221, 2021. Moderate angle cutting maneuvers (between 45º and 90º) are common and essential performance skills for success in multidirectional sports. Research addresses the injury risks of cutting but few studies have attempted to quantify the performance of the cut itself. PURPOSE: To identify any anthropometric, kinematic, and/or kinetic markers of a high-performance cut so they may be taught and lead to more effective training. METHODS: Ten college-aged male athletes (mass 73.97 ± 8.77kg, height 1.81 ± 0.07m) and ten non-athletes (mass 87.37 ± 13.93kg, height 1.85 ± 0.04m) completed five moderate angle cutting …

The Effect Of The Difference In The Perception Of Temperature Between Sexes On The Academic Performance Of Chapin High School Students, Tiffany V. Phan

Journal of the South Carolina Academy of Science

Mental performance and mental functions may be negatively affected by decreases in thermal comfort as a result of large differences in temperature. Additionally, females are seen to be less content with room temperatures and actually prefer rooms with higher temperatures in comparison to males. This investigation explored the potential effect that sex plays in thermal perception and the impact it may yield on academic performance within a high school population. It was hypothesized that female students would experience an increase in academic performance as the temperature increased while males would experience the opposite effect. A quasi-experimental approach was used to …

Experimental Pharmacotherapies In Models Of Alcohol Addiction, Mousumi Akter Sumi

Theses and Dissertations

The USA faces $220 billion economic loss and eighty thousand deaths per year due to alcohol abuse while affecting more than 15 million people, making it the third largest life-style related cause of death. The U.S. FDA has approved four medications namely, disulfiram, acamprosate, oral naltrexone, and injectable long-acting naltrexone. These existing drugs are trashed with side effects, have a low success rate, indicating a demand for new potential drugs. We studied the effects of the CB1 negative allosteric modulator, PSNCBAM-1, and the dopamine D4 receptor antagonist, L-745,870 in mouse models of alcohol addiction. PSNCBAM-1 did not significantly reduce CPP …

Overstraining Human Nature In The Nicomachean Ethics, Douglass Reed

Philosophy Faculty Publications

In this paper, I investigate Aristotle’s claim in Nicomachean Ethics III.1 about situations that “overstrain human nature.” By setting out and answering several interpretative questions about such situations, I offer a comprehensive interpretation of this passage. I argue that in (at least some of) these cases, the agent voluntarily does something wrong, even though there is a right action available. Furthermore, I argue that Aristotle would think it is possible for a rare agent to perform the right action in (at least some of) these cases, overcoming the limitations of human nature by identifying with the divine part of the …

Knowledge Network Embedding Of Transcriptomic Data From Spaceflown Mice Uncovers Signs And Symptoms Associated With Terrestrial Diseases, Amber M. Paul, Charlotte A. Nelson, Ana Uriarte Acuna, Ryan T. Scott, Atul J. Butte, Egle Cekanaviciute, Sergio E. Baranzini

Publications

There has long been an interest in understanding how the hazards from spaceflight may trigger or exacerbate human diseases. With the goal of advancing our knowledge on physiological changes during space travel, NASA GeneLab provides an open-source repository of multi-omics data from real and simulated spaceflight studies. Alone, this data enables identification of biological changes during spaceflight, but cannot infer how that may impact an astronaut at the phenotypic level. To bridge this gap, Scalable Precision Medicine Oriented Knowledge Engine (SPOKE), a heterogeneous knowledge graph connecting biological and clinical data from over 30 databases, was used in combination with GeneLab …

Central Washington University 2021-2022 Graduate Catalog, Central Washington University

Course Catalogs

No abstract provided.

The Impact Of Visual Literacy In Secondary Science Education, Elise M. Miller

All Electronic Theses and Dissertations

Visual literacy, or the ability to make sense of and produce images, is an essential but long underrated skill in science. Career scientists and engineers decode and encode information in pictorial form using visual literacy skills regularly. This research will explore first the purpose of science education in the United States and how its reforms have been influenced by career scientists. It will explore if visual literacy skills are aligned with these purposes. This research will then investigate the benefits of incorporating visual literacy in science education to this end. Finally, this research will outline research-based instructional strategies for integrating …

Role Of Na/K-Atpase Non-Enzymatic Signaling In Renal Proximal Tubule Sodium Transport, Shreya Tapan Mukherji

Theses, Dissertations and Capstones

The renal proximal tubule (RPT) is the center stage for renal handling of Na+ , a potent determinant of systemic Na+ and volume homeostasis in health and disease. In the RPT, through its classic ion-pumping function, Na + /K+ -ATPase (NKA) generates the Na+ gradient that drives apical Na+ absorption, mostly through Na+ /H+ exchanger (NHE3). In contrast, pharmacological evidence suggests that the activation of the NKA non-enzymatic signaling function, through Src and other signaling partners, triggers a cellular redistribution of NKA and NHE3 that decreases transcellular Na+ flux in cultured RPT cells. However, the physiological relevance of the nonenzymatic …

The Effects Of Endocrine Disrupting Chemicals On Plants, Christian Mathew Pridemore

Theses, Dissertations and Capstones

Endocrine disrupting chemicals (EDCs) are a diverse group of chemicals which can have a detrimental effect on human health, affecting any physiological body system sensitive to hormonal changes. Human exposure to EDCs is inevitable due to their prevalence in modern living; EDCs are integral compounds found in everyday items with which humans interact and ingest. These, along with other indirect avenues leading to EDC exposure, pose a threat to both human health and to the health of wildlife and agricultural environments. Studies on the effects of EDCs on plants can be substantially informative and necessary for progress towards solving the …

Taylor University Catalog 2021-2022, Taylor University

Undergraduate Catalogs

The 2021-2022 academic catalog of Taylor University in Upland, Indiana.

Physician Assistant_Fort Lauderdale_2021, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Approved General Education (Ge) Distribution Courses, Kean University

Evidence Inventory

General Education Program's List of Approved Distribution Courses

A Review Of Contemporary Techniques For Measuring Ergonomic Wear Comfort Of Protective And Sport Clothing, Yetanawork Teyeme, Benny Malengier, Tamrat Tesfaye, Izabela Ciesielska-Wrobel, Atiyyah Binti Haji Musa, Lieva Van Langenhove

Textiles, Fashion Merchandising and Design Faculty Publications

Protective and sport clothing is governed by protection requirements, performance, and comfort of the user. The comfort and impact performance of protective and sport clothing are typically subjectively measured, and this is a multifactorial and dynamic process. The aim of this review paper is to review the contemporary methodologies and approaches for measuring ergonomic wear comfort, including objective and subjective techniques. Special emphasis is given to the discussion of different methods, such as objective techniques, subjective techniques, and a combination of techniques, as well as a new biomechanical approach called modeling of skin. Literature indicates that there are four main …

Adaptive Two-Stage Edge-Centric Architecture For Deeply-Learned Embedded Real-Time Target Classification In Aerospace Sense-And-Avoidance Applications, Nicholas A. Speranza

Browse all Theses and Dissertations

With the growing number of Unmanned Aircraft Systems, current network-centric architectures present limitations in meeting real-time and time-critical requirements. Current methods utilizing centralized off-platform processing have inherent energy inefficiencies, scalability challenges, performance concerns, and cyber vulnerabilities. In this dissertation, an adaptive, two-stage, energy-efficient, edge-centric architecture is proposed to address these limitations. A novel, edge-centric Sense-and-Avoidance architecture framework is presented, and a corresponding prototype is developed using commercial hardware to validate the proposed architecture. Instead of a network-centric approach, processing is distributed at the logical edge of the sensors, and organized as Detection and Classification Subsystems. Classical machine vision algorithms are …

Anatomy Master's Degree Annual Program Outcomes Assessments, 2020-21, College Of Science And Mathematics, Wright State University

Annual Program Outcomes Assessments - All

This report reviews Wright State University's Anatomy Master's Degree program for the 2020-2021 academic year.

Characterization Of Clostridium Cochlearium As A Potential Probiotic For Obesity Management, Paba Edirisuriya

Wayne State University Dissertations

ABSTRACTCHARACTERIZATION OF CLOSTRIDIUM COCHLEARIUM AS A POTENTIAL PROBIOTIC FOR OBESITY MANAGEMENT

ByPABA EDIRISURIYA MAY 2021 Advisor: Dr. Kequan Zhou Major: Nutrition and food science Degree: Doctor of Philosophy Emerging evidence indicates that manipulation of gut microflora is a potential therapeutic approach for managing obesity. Probiotic effects on host weight reduction have repeatedly been revealed through previous studies. Clostridium cochlearium is a butyrate-producing, spore-forming bacteria that have been reported to present in the mammalian gut. Our simulated Invitro digestion model revealed that C. cochlearium could survive in the unfavorable conditions of the human gastrointestinal tract, including low pH (pH2), high bile …

The Role Of Nutrient Availability In Therapeutic Response Of Leukemia, Rohiverth Guarecuco Jr.

Student Theses and Dissertations

Tumor environment influences the response to anti-cancer therapy, but which extracellular nutrients impact drug sensitivity is largely unknown. In this work, we used functional genomics to identify metabolic modifiers of the response to L-asparaginase (ASNase), a therapy that depletes plasma asparagine and targets leukemic cells with insufficient asparagine synthesis. Our approach revealed thiamine pyrophosphate kinase 1 (TPK1), which converts vitamin B1 (thiamine) into the cofactor thiamine pyrophosphate (TPP), as a metabolic dependency under ASNase treatment. In glutamine-anaplerotic leukemia cells, we found that TPP availability enables asparagine synthesis from extracellular glutamine. Mechanistically, TPP is critical for the activity of alpha-ketoglutarate dehydrogenase …

Transcriptional Regulation Of The Metabolic Response To Therapy In Leukemia, Robert Thomas Williams

Student Theses and Dissertations

Cancer cells are under constant stress due to their uncontrolled growth, oncogenic signaling, and the metabolic insufficiencies of their microenvironments. Under various stresses, cells activate the integrated stress response (ISR), a transcriptional program to restore cellular homeostasis. Activating transcription factor 4 (ATF4) acts as the master transcriptional regulator of the ISR by promoting the transcription of genes that mitigate stress or promote cell death if the stress remains unresolved. Despite being the common mediator of various stress response and metabolic pathways, ATF4 generates tailored transcriptional outputs to distinct cellular stresses by cooperating with other transcriptional machinery. The precise mechanisms by …