A Proposed Typology Of Nos Empirical Research: Trends And Implications, Maryam Saberi, Noushin Nouri, William F. Mccomas

Teaching and Learning Faculty Publications

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Nature of Science (NOS) is a vital school subject with extensive publication record including results from many empirical investigations. This project examined the range, nature, and trends in empirical NOS studies from six major science education research journals over a recent 25-year period with additional recent data. Using systematic literature review techniques (SLR) and subsequent qualitative methods, we developed a comprehensive typology of empirical NOS articles. Ten categories emerged: Teaching NOS to students; Teaching NOS to teachers; Teachers’ NOS classroom practices and knowledge transfer; NOS assessment development and application; Analyses of textbooks and science curricula; Relationships between NOS knowledge and …

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Maternal Health And Sociodemographic Characteristics Influence Infant Growth To 24 Months In The Tunza Mwana Cohort: A Prospective Cohort Study, David Taylor Hendrixson, Mark J Manary, Et Al.

2020-Current year OA Pubs

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Upstream pathways influencing child growth are complex. Weight-for-age z-score (WAZ) reflects both ponderal and linear growth and can identify children at high mortality risk. Using data from a prospective cohort of 326 mother-child pairs in Kenya, we evaluated whether associations between maternal exposures and child growth outcomes in early and later childhood. Growth trajectories were examined using locally weighted scatterplot smoothing and piecewise linear mixed-effect models with a knot at age 3 months. Poisson regression models examined associations between maternal characteristics and child underweight (WAZ <  -2) and stunting (LAZ <  -2) before and after 3 months. Mean WAZ increased to a peak at 3 months before declining steadily through 24 months. Lower maternal education (adjusted β [aβ] -0.18; 95% CI: -0.24, -0.13), household crowding (aβ -0.2; 95% CI: -0.28, -0.11), lower wealth quintile (aβ -0.04; 95% CI: -0.06, -0.02) and multiparity (aβ -0.16; 95% CI: -0.23, -0.1) were associated with lower monthly rate of change in WAZ prior to age 3 months. Younger maternal age was associated with an increased monthly rate of change in WAZ (aβ = 0.13; 95% CI: 0.08, 0.18) before 3 months and decreased monthly WAZ (aβ -0.02; 95% CI: -0.03, -0.01) after 3 months. Preterm birth was associated with increased risk of underweight in both periods (aRR 2.77; 95% CI: 1.39-5.50). Maternal mental health, intimate partner violence and adverse childhood experiences were not significantly associated with child growth. Maternal nutritional, socio-economic and household-level factors shape early growth, emphasising the need for cross-sectoral programs to support growth.

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Patient-Centered Approach To Surgical Prevention Of Ovarian Cancer: A Nonrandomized Clinical Trial, Karen H Lu, Andrea R Hagemann, Et Al.

2020-Current year OA Pubs

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IMPORTANCE: Risk-reducing salpingo-oophorectomy (RRSO) is an effective option to prevent ovarian cancer in high-risk individuals, but adverse effects from premature menopause are a barrier to uptake. Interval salpingectomy with delayed oophorectomy (ISDO) may be an effective alternative.

OBJECTIVE: To evaluate the association of ISDO vs RRSO and sexual function and menopausal symptoms.

DESIGN, SETTING, AND PARTICIPANTS: This prospective, multicenter, nonrandomized (patient preference) clinical trial was performed among Women Choosing Surgical Prevention participants with a pathogenic or likely pathogenic germline variant conferring an increased risk for ovarian cancer. Patients from 9 US centers were enrolled from June 2, 2016, to October …

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Hepatitis B In The Vaccine Era: Persistent Burden And Clinical Implications, Cherechi Nwabueze, Eunice Omeludike, Ridwan Ademola Lawal, Kedife Nwabueze

School of Medicine Publications

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Hepatitis B virus (HBV) infection remains a leading global cause of advanced liver disease and imposes a substantial economic burden. Early prevention is critical, as perinatally acquired HBV carries a high risk of progression to cirrhosis or hepatocellular carcinoma (HCC). Hepatitis B vaccination has been proven effective in preventing cancer, yet coverage of the complete vaccine series remains suboptimal. This implementation gap perpetuates the clinical burden, manifesting decades later as hepatic decompensation and liver cancer. This narrative review synthesizes the current HBV landscape, highlighting how gaps in vaccination policy and delivery contribute to real-world gastrointestinal outcomes. By reframing HBV vaccination …

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Not Just A Migraine: Transverse Venous Sinus Stenosis Presenting As Orthostatic Headache, Tejaswini Swamy, Aun A. Bangash, Chloe Harris, Jose E. Campo Maldonado

School of Medicine Publications

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Transverse venous sinus stenosis (TVSS) is an underrecognized cause of intracranial hypertension that can mimic primary headache disorders. We report a woman with obesity and prior bariatric surgery who developed bifrontal headache with pulsatile tinnitus, dizziness, and visual blurring for 1 year. Orthostatic features and lack of response to therapy prompted further evaluation. Lumbar puncture revealed an opening pressure of 32 cm H2 O with immediate relief after cerebrospinal fluid removal. Magnetic resonance venography demonstrated severe TVSS, confirmed by cerebral angiography. The patient had left transverse sinus stenting with sustained improvement. This case highlights the importance of considering TVSS in …

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Professional Dispositions In Coaching Education: Icf-Credentialed Coaches’ Perspectives On Development And Assessment, Michelle Renee Thompson

Electronic Theses and Dissertations

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This qualitative phenomenological study examined how professional dispositions were defined, experienced, and assessed in coaching education within the rapidly expanding field of professional coaching. The problem addressed was the lack of a clear understanding of professional dispositions in coaching and the absence of a systematic dispositional assessment comparable to that in counselor education. The researcher’s purpose was to explore how credentialed professional-level coaches defined and identified professional dispositions for effective coaching engagements and how these dispositions aligned with constructs in other helping professions. The researcher collected data through semistructured videoconference interviews. Purposeful and snowball sampling yielded 16 U.S.-based coaches who …

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A Perspective As Observed By Public Middle School Teachers On A Lack Of Empathy Demonstrated By Public Middle School Students, Gail P. Hall

Electronic Theses and Dissertations

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The purpose of this qualitative descriptive study was to explore a perspective as observed by public middle school teachers on a lack of empathy demonstrated by public middle school students. The research analyzed how public middle school teachers in the southern region of Texas described their perception of how a lack of empathy demonstrated by public middle school students impacted students during the school day. The study involved 10 selected participants who participated in a semistructured open-ended interview on the Google Meet platform. The participants consisted of 90% female and 10% male, with a combined total of 91 years of …

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Attendance And Academic Performance: A Comparison Of 4-Day And 5-Day School Week Schedules In Texas High Schools, Cynthia Miles

Electronic Theses and Dissertations

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This quantitative cross-sectional comparable study examined the differences in academic performance and attendance in Texas public high school campuses between those operating on a 4-day instructional week and those operating on a 5-day instructional week. The study used a quantitative, cross-sectional comparable design. The analysis included campus-level data from the Texas Education Agency’s Texas Academic Performance Reports. The independent variable was instructional schedule—either a 4-day or a 5-day instructional week. The dependent variables included campus attendance rates and student performance on the English I and Algebra I End-of-Course (EOC) STAAR (State of Texas Assessments of Academic Readiness) assessments of ninth-grade …

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Mab-Dqa: Addressing Query Aspect Importance In Document Question Answering With Multi-Armed Bandits, Yixin Xiang, Yunshan Ma, Xiaoyu Du, Yibing Chen, Yanxin Zhang, Jinhui Tang

Research Collection School Of Computing and Information Systems

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Document Question Answering (DQA) involves generating answers from a document based on a user’s query, representing a key task in document understanding. This task requires interpreting visual layouts, which has prompted recent studies to adopt multimodal Retrieval-Augmented Generation (RAG) that processes page images for answer generation. However, in multimodal RAG, visual DQA struggles to utilize a large number of images effectively, as the retrieval stage often retains only a few candidate pages (e.g., Top-4), causing informative but less visually salient content to be overlooked in favor of common yet low-information pages. To address this issue, we propose a Multi-Armed Bandit–based …

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Transoral Endoscopic Stapled Diverticulotomy For Pediatric Esophageal Diverticulum: A Case Report, Nadeen Alturki, Huma Quraishi, Keith A. Kuenzler

Manuscripts, Articles, Book Chapters and Other Papers

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Introduction

Pharyngoesophageal diverticula are rare in the pediatric population and are typically managed with open surgical approaches. Minimally invasive surgical (MIS) approaches are well established in adults however, to date, no MIS technique for pediatric esophageal diverticula has been described in the literature.

Case presentation

A 12-year-old female presented with neck and chest pain, dysphagia, and difficulty breathing and speaking following ingestion of food from a broken glass jar. Imaging demonstrated a retropharyngeal abscess with a retained foreign body requiring thoracoscopic drainage. The patient subsequently developed a cervical esophageal diverticulum associated with persistent symptoms. She underwent transoral endoscopic stapled diverticulotomy …

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Loss Of Palmitoylation Impacts The Interaction Between The Organic Anion Transporting Polypeptide (Oatp) 1b1 And Oatp1b3., Cecilia E. Villanueva, Whitney M. Nolte, Priscilla Flores-Ascencio, Bruno Hagenbuch

Manuscripts, Articles, Book Chapters and Other Papers

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The organic anion transporting polypeptide (OATP) 1B1 and OATP1B3 are hepatic transporters that mediate the uptake of numerous therapeutics like antibiotics and statins. Various post-translational modifications, eg, phosphorylation and glycosylation, have been shown to impact OATP1B1 and OATP1B3 function and localization. S-palmitoylation (also known as S-acylation or palmitoylation) is a reversible post-translational modification that adds palmitic acid (C16:0) to cysteine residues and can influence a protein's function, localization, and protein-protein interactions. In this study, we investigated and characterized palmitoylation in OATP1B1 and OATP1B3. Using site-directed mutagenesis and acyl-resin-assisted capture assays, residue Cys24 was identified as the palmitoylation site for both …

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Factors Associated With Pre-Donation Health-Related Quality-Of-Life Among Pediatric Sibling Hematopoietic Cell Donors: A Donorkids Ql Study., Galen E. Switzer, Jessica G. Bruce, Bronwen E. Shaw, Vidya Kuniyil, James W. Varni, Brandan J. Butler, Connor Erickson, Alisha Mussetter, Allison Neutzling, Hisham Abdel-Azim, Paibel Aguayo-Hiraldo, Eric J. Anderson, Victor M. Aquino, Karlie Boone, Farid Boulad, Joseph H. Chewning, Jessica Cooper, Ann Dahlberg, Christopher C. Dvorak, Jorge Galvez-Silva, Ann E. Haight, Jennifer A. Hoag, Michelle Hudspeth, David Jacobsohn, Kimberly A. Kasow, Carrie L. Kitko, Lakshmanan Krishnamurti, Lisa Madden, Holly K. Miller, Erin Morales, Timothy S. Olson, Anna B. Pawlowska, Vinod K. Prasad, Troy C. Quigg, Andromachi Scaradavou, Niketa C. Shah, Shalini Shenoy, Nancy Terwilliger, Lori Wiener, Gregory A. Yanik, Lolie C. Yu, Michael A. Pulsipher

Manuscripts, Articles, Book Chapters and Other Papers

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Due to limited published data assessing pediatric hematopoietic cell donor experiences, we previously conducted one of the largest quantitative investigations of pediatric donor experiences and health-related quality-of-life (HRQoL) at the time (RDSafe). Findings from RDSafe demonstrated that a subset of pediatric HC donors experienced very poor HRQoL; unfortunately, that dataset addressed only a limited number of factors, and key associations explaining this poor HRQoL were not found. In this study, our goal was to address that deficit by describing pre-donation donor HRQoL in detail and identifying factors across five key domains that were associated with donor HRQoL. We conducted a …

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How To Assess Ventricular Function By Fetal Echocardiography: Expert Guidance From The Fetal Heart Society., S R Patel, Nitin Madan, L Eckersley, Z Roytman, M Perez, L Gindes, L K Hornberger

Manuscripts, Articles, Book Chapters and Other Papers

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No abstract provided.

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Current Practices And Variations Among Pediatric Severe Asthma Programs In The United States-The North American Severe Pediatric Asthma Consortium., Kristina Gaietto, Nadia Krupp, Avani V. Shah, Erhan Ararat, Samantha H. Averill, Sachin Baxi, Matejka Cernelc-Kohan, Jeffrey M. Chambliss, Heather De Keyser, Monica Federico, Bob Geng, Akilah A. Jefferson, Parisa Kaviany, Lila C. Kertz, Kirsten Kloepfer, Allyson Larkin, Sydney Leibel, Tanya Martinez-Fernandez, Samira Naime, Robert D. Pesek, Dinesh K. Pillai, Deepa Rastogi, Katherine Rivera-Spoljaric, Kristie R. Ross, Franziska J. Rosser, Tregony C. Simoneau, Jade Tam-Williams, Kelan G. Tantisira, William Anderson, Jonathan M. Gaffin, Theresa W. Guilbert, Erick Forno

Manuscripts, Articles, Book Chapters and Other Papers

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BACKGROUND: Severe and difficult to treat asthma in children is a complex condition causing significant morbidity and associated healthcare costs. While treatment guidelines exist for severe asthma, optimal treatment approaches for the pediatric population are less well established. Furthermore, best practices regarding real world management and implementation of guidelines for the severe pediatric asthma population are lacking. In order to provide care for this population, institutions around the United States have developed multidisciplinary severe pediatric asthma programs (SPAPs). In recent years, the North American Severe Pediatric Asthma Consortium (NASPAC) was established as a mechanism for SPAPs to collaborate and share …

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Conceptualizations Of "Public Health" And Government Action Among U.S. Adults In 2025., Lauren Yan, Emily Cramer, Peter J. Winch, Emily A. Hurley

Manuscripts, Articles, Book Chapters and Other Papers

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INTRODUCTION: Understanding how Americans think about public health and the role of government institutions is crucial for informing effective health communication in a polarized political climate.

METHODS: We deployed an open-ended national survey of 1004 adults in October 2025 to assess public perceptions of these topics.

RESULTS: Respondents associated the term "public health" with health for everyone (44%) and health of everyone (23%), alongside healthcare (20%) and other themes. The most common perceived government benefit was facilitating access to healthcare (39%)-particularly by addressing cost (16%). Among perceived government harms, more Republicans than Democrats cited overregulation (16% vs 8%, P < 0.01), limiting …

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