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Soybean Embryogenic Cell Culture Genetically Engineered, Gabriel Carrasquillo Jun 2025

Soybean Embryogenic Cell Culture Genetically Engineered, Gabriel Carrasquillo

Tennessee State University Alumni Theses and Dissertations

The inflation of population in the world has led to a high and consistent food demand which has reinvigorated worldwide interest to create high-yielding varieties of legumes. Soybean Glycine max (L.) Merrill, a member of this legume family has become one of the most essential food crops in the United States as well as in the world due its edible oil and protein content up to 20% and 54%, respectively. Because of its high importance as a food crop, major objectives in soybean breeding, improvement of protein and oil production need to be achieved. These objectives can be addressed using …


Examining Disproportionate Discipline Through Teacher Discipline Referrals: A Mixed Methods Analysis, Shivon A. Griffey Jun 2025

Examining Disproportionate Discipline Through Teacher Discipline Referrals: A Mixed Methods Analysis, Shivon A. Griffey

Tennessee State University Alumni Theses and Dissertations

This study examined the impact of the racial composition of teachers on disciplinary practices within a school, specifically focusing on how the lack of demographic representation contributes to disciplinary disparities experienced by students from underrepresented groups. Employing a mixed methods approach, the research integrated qualitative data from focus group with quantitative analysis. Thematic analysis revealed key themes related to (a) perceptions of disciplinary fairness, (b) cultural competence, (c) representation (d) student-teacher relationships, (e) professional development, (f) and community and parental perspectives. Additionally, a chi squared test was conducted to assess if there was a statistically significant difference in the expected …


Navigating Sorghum Bicolor Microspores For Genetic Transformation Via Androgenic Pathway During Gametogenesis, Aron M. Felts Jun 2025

Navigating Sorghum Bicolor Microspores For Genetic Transformation Via Androgenic Pathway During Gametogenesis, Aron M. Felts

Tennessee State University Alumni Theses and Dissertations

This study delves into the use of the androgenesis pathway of microspores for genetic transformation and double haploid production in Sorghum bicolor. Focusing on the environmental and genetic factors that affect androgenesis, in vitro culture techniques were aimed to be refined for utilizing microspores towards callus induction more effectively. These efforts yielded promising approaches for agronomic traits enhancements. This research enhances the methodology for plant regeneration from microspores, facilitating the generation of homozygous lines with potentially improved traits. Although the current findings do not mark a radical departure from existing knowledge, they lay essential groundwork for future genetic studies in …


Microwave-Assisted Synthesis And Surface Characterization Of Graphene Oxide-Antimony Trioxide Nanocomposites For Ascorbic Acid Electrochemical Sensor, Samir Mallick Jun 2025

Microwave-Assisted Synthesis And Surface Characterization Of Graphene Oxide-Antimony Trioxide Nanocomposites For Ascorbic Acid Electrochemical Sensor, Samir Mallick

Tennessee State University Alumni Theses and Dissertations

The detection and monitoring of Ascorbic Acid (AA) concentration is of crucial importance. Abnormal AA levels in bodily fluids have been reported to cause cancer, cardiovascular diseases, and Alzheimer’s and Parkinson’s diseases. Nanoparticles have played a critical role in developing affordable, sensitive, and selective sensors. This work reports on the electrochemical detection of AA using glassy carbon electrodes (GCEs) modified with microwave-assisted graphene oxide-antimony trioxide nanocomposite and chitosan films. The developed sensor displayed enhanced electron transfer and a better electrocatalytic reaction towards AA compared to other fabricated electrodes. Cyclic voltammetry and chronoamperometry were used for electrochemical measurements. CV and Fourier …


Deep Imputation Of Missing Values Using Feature And Sample Attention, Ibna Kowsar Jun 2025

Deep Imputation Of Missing Values Using Feature And Sample Attention, Ibna Kowsar

Tennessee State University Alumni Theses and Dissertations

The handling of missing values is a pervasive challenge in tabular data sets, particularly in electronic health records (EHR), where incomplete data can hinder predictive modeling. Data with missing values are unfit for machine learning, whereas the imputation of missing values affects data quality and data-driven outcomes. Traditional statistical and machine learning-based imputation techniques often struggle with high missing rates and complex missing patterns. This thesis investigates the deep learning of attention between features and between samples in missing value imputation. These two attention mechanisms jointly capture the row-column structure of tabular data. It presents a novel deep learning framework …


Privacy-Preserving Ai Framework Using He-Fl For Electric Utility Infrastructure Defect Detection, Tupac S. Moseley Jun 2025

Privacy-Preserving Ai Framework Using He-Fl For Electric Utility Infrastructure Defect Detection, Tupac S. Moseley

Tennessee State University Alumni Theses and Dissertations

In modern times, electric utility companies are utilizing on-ground and aerial drone imagery to identify physical defects on transmission and distribution infrastructure to plan for more effective maintenance. To deploy faster and more cost-efficient maintenance decisions, utility companies are considering developing automation tools powered by AI. However, for AI technology to be effectively trained for real-world implementation, there is a need for cross-collaboration among a vast number of utility companies to share their imagery and analysis to improve the global AI model. The primary challenge of this collaboration comes at the expense of requiring data cleaning, a manual process to …


Faculty Adoption And Awareness Of Online Education Technologies And 360° Video, Carrie Elizabeth Cook Jun 2025

Faculty Adoption And Awareness Of Online Education Technologies And 360° Video, Carrie Elizabeth Cook

Tennessee State University Alumni Theses and Dissertations

This study explored faculty perceptions of distance education and the potential integration of immersive 360° video technology in higher education. To understand how faculty use online learning and a specific form of immersive learning, the Technology Acceptance Model (TAM) served as the theoretical foundation for this study. This study employed a descriptive research design to assess faculty attitudes, and surveys conducted with a researcher adapted version of a proven instrument were conducted with Tennessee State University (TSU) faculty. The findings of this study revealed that faculty perceptions of distance education were influenced by concerns about engagement, technological barriers, and comparisons …


Seed Careers App Impact On Nextgen Scholars At Tennessee State University, Jazmine Norwood Jun 2025

Seed Careers App Impact On Nextgen Scholars At Tennessee State University, Jazmine Norwood

Tennessee State University Alumni Theses and Dissertations

The underrepresentation of minority groups in food, agriculture, natural resources, and human sciences (FANHS) careers remains a challenge, limiting diversity and growth within the industry. Agriculture degrees have been disproportionately awarded to White students, while Hispanic, Black, and Native American students receive significantly fewer degrees. Research suggests that financial assistance, experiential learning, and career outreach improve minority student retention and success in FANHS. To address these challenges, the USDA’s NextGen program awarded $18.1 million to Tennessee State University (TSU) to support underserved students through scholarships, internships, and career development initiatives, including the creation of the Students Exploring Employment and Development …


Harmful Algae In Nashville’S Urban Watersheds: Challenging Traditional Monitoring Programs, Devin Matthew Moore Jun 2025

Harmful Algae In Nashville’S Urban Watersheds: Challenging Traditional Monitoring Programs, Devin Matthew Moore

Tennessee State University Alumni Theses and Dissertations

As climate change intensifies, harmful algal blooms (HABs), specifically the species that produce microcystin-producing cyanobacteria, are becoming more frequent in urban environments. In the current state of HAB research, most monitoring and research is focused on agricultural areas. This study challenges traditional monitoring practices by evaluating the presence and abundance of microcystin in urban water bodies within Nashville, TN. Using field sampling, passive toxin tracking, ELISA testing, and GIS- based environmental and demographic analysis, data were collected at sites in densely populated areas. These sites were located at Tennessee State University, Ted Rhodes golf course and Shelby bottoms Park, and …


Ethical Leadership Of Universities Concerning Outreach Efforts During Covid-19, Sandra Bogard Jun 2025

Ethical Leadership Of Universities Concerning Outreach Efforts During Covid-19, Sandra Bogard

Tennessee State University Alumni Theses and Dissertations

Navigating the COVID-19 pandemic proved challenging for Institutions of Higher Education. This study investigated the responses of higher education leadership to the pandemic as it related to their outreach efforts to assist their local community and healthcare system. The crisis leadership theory directed this research, focusing on the importance of leadership roles within institutions of higher education and how they responded to a crisis. This research concentrated on university leadership and whether they felt ethically obligated to assist their community during the pandemic, how they assisted, and whether they perceived their assistance as imperative for the community to overcome the …


Exploring Post-Pandemic School Leadership Through Experience, Teacher Perception, And Self-Efficacy, Nasheba Pritchett Jun 2025

Exploring Post-Pandemic School Leadership Through Experience, Teacher Perception, And Self-Efficacy, Nasheba Pritchett

Tennessee State University Alumni Theses and Dissertations

The COVID-19 pandemic significantly disrupted the educational landscape, creating unprecedented challenges for instructional leaders. This qualitative phenomenological study explored how middle school leaders in Tennessee navigated these challenges, particularly regarding excessive teacher absenteeism, mental and physical health concerns, teacher retention, and the design and provision of instructional support. By capturing the lived experiences of middle school leaders, this study examined their self-efficacy in addressing these post-pandemic issues and their preparedness to support teachers effectively. Utilizing a phenomenological approach, the study investigated the perceptions and strategies of middle school leaders who served in grades 5 through 8 before, during, and after …


Our Hbcus Matter: Factors Influencing Hbcus’ Graduation Rates, Brandon Markelle Graham Jun 2025

Our Hbcus Matter: Factors Influencing Hbcus’ Graduation Rates, Brandon Markelle Graham

Tennessee State University Alumni Theses and Dissertations

This qualitative comparative multi case study examined how institutional practices, leadership philosophies, and academic support systems affect Pell Grant recipients' student success at Atlantic A&M University (AAMU) and Heritage State University (HSU). Based on Swail's Geometric Model of Student Persistence and Achievement, the study examined cognitive, institutional, and social factors of student success using institutional data, NCES datasets, and two former HBCU presidents' perspectives. Semi-structured interviews with former tenured HBCU presidents illuminated how financial constraints, performance-based accountability metrics, and admissions standards shaped campus strategies from 2012 to 2021. The study examined first-time, first-year Pell Grant recipients' graduation outcomes, standardized test …


Career Decision-Making Self-Efficacy Of Tennessee State University Agriculture Students, Jeiel Ballard Jun 2025

Career Decision-Making Self-Efficacy Of Tennessee State University Agriculture Students, Jeiel Ballard

Tennessee State University Alumni Theses and Dissertations

The focus of this research was Tennessee State University (TSU) Department of Agricultural and Environmental Sciences (DAES) undergraduate students’ interest in a career in agriculture and their belief in their ability to make career decisions. It is important to develop an understanding of the types of TSU students who choose to major in agricultural sciences and choose a career in the same, and to identify their Career Decision-making Self-efficacy (CDSE) so that current and future students can be best guided in job and career choice, preparation, and transitions. The Betz and Taylor (1983) Career Decision Making Self Efficacy Theory and …


Application Of High-Pressure Processing And Real-Time Pcr For Preventing Foodborne Bacterial Diseases, Ranju Kafle Jun 2025

Application Of High-Pressure Processing And Real-Time Pcr For Preventing Foodborne Bacterial Diseases, Ranju Kafle

Tennessee State University Alumni Theses and Dissertations

Foodborne pathogens pose significant risks to public health and food safety, necessitating innovative control strategies. High-pressure processing (HPP) was evaluated as an intervention against Listeria monocytogenes in cold-smoked rainbow trout, with treatments at 500 MPa and 4.4 °C and 60.0 °C achieving up to a 5.03 log CFU/g reduction. The efficacy of nisin in suppressing Listeria monocytogenes and Listeria innocua during refrigerated storage was also examined, demonstrating significant microbial inhibition, particularly in the early storage phase, supporting its application as a hurdle technology. Additionally, the synergistic effects of HPP (400 MPa, 4 °C) and natural bioactive compounds, including lactic acid, …


Mutation Of Smarca4 Induces Cancer Cell-Intrinsic Defects In The Enhancer Landscape And Resistance To Immunotherapy, Yawen Wang, Ismail M Meraz, Md Qudratullah, Sasikumar Kotagiri, Yanyan Han, Yuanxin Xi, Jing Wang, Kadir C Akdemir, Jack A Roth, Yonathan Lissanu Jun 2025

Mutation Of Smarca4 Induces Cancer Cell-Intrinsic Defects In The Enhancer Landscape And Resistance To Immunotherapy, Yawen Wang, Ismail M Meraz, Md Qudratullah, Sasikumar Kotagiri, Yanyan Han, Yuanxin Xi, Jing Wang, Kadir C Akdemir, Jack A Roth, Yonathan Lissanu

Faculty, Staff and Student Publications

Cancer genomic studies have identified frequent alterations in genes encoding components of the SWI/SNF chromatin remodeling complex, including SMARCA4 and ARID1A. Importantly, clinical reports indicate that SMARCA4-mutant lung cancers respond poorly to immunotherapy and have dismal prognosis. In this study, we corroborated the clinical findings by using immune-humanized, syngeneic, and genetically engineered mouse models of lung cancer harboring SMARCA4 deficiency. Specifically, models with SMARCA4 loss showed decreased response to anti-PD-1 immunotherapy associated with significantly reduced infiltration of dendritic cells and CD4+ T cells into the tumor microenvironment. SMARCA4 loss in tumor cells led to profound downregulation of STING1, IL1β, and …


Measuring Emotional Intelligence With The Msceit 2: Theory, Rationale, And Initial Findings, John D. Mayer, David R. Caruso, Peter Salovey, Iris Y. Lin, Braden J. Hansma, Joanna Solomon, Gill Sitarenios, Manolo Romero Escobar Jun 2025

Measuring Emotional Intelligence With The Msceit 2: Theory, Rationale, And Initial Findings, John D. Mayer, David R. Caruso, Peter Salovey, Iris Y. Lin, Braden J. Hansma, Joanna Solomon, Gill Sitarenios, Manolo Romero Escobar

UNH Personality Lab

Introduction: The model of emotional intelligence as an ability has evolved since its introduction 35 years ago. The revised model includes that emotional intelligence (EI) is a broad intelligence within the Cattell-Horn-Carroll (CHC) model of intelligence, and that more areas of problem solving are involved than originally detailed. An argument is made here that veridical scoring of EI test responses is a sound procedure relative to scoring keys based on expert consensus or a single emotion theory. To the degree that EI fits present-day theories of intelligence (i.e., the CHC model), any subsidiary factors of EI reasoning should correlate highly …


Social Exclusion And Mental Health Of Youths Affected By Parental Hiv/Aids In China: Based On A Serial Mediating Model, Jiaojiao Wan, Lili Ji, Zheqian Wang, Junfeng Zhao, Xiaoming Li Jun 2025

Social Exclusion And Mental Health Of Youths Affected By Parental Hiv/Aids In China: Based On A Serial Mediating Model, Jiaojiao Wan, Lili Ji, Zheqian Wang, Junfeng Zhao, Xiaoming Li

Faculty Publications

The mental health of youth living with patients with HIV needs focused attention. The primary source of psychological distress they experience may stem from social exclusion. Therefore, the current study was designed to explore the relationship between social exclusion and mental health among youths affected by parental HIV/AIDS in rural China.

Methods

297 youths affected by parental HIV/AIDS were recruited to completed questionnaires of social exclusion, perceived stress, future orientation and mental health. The bootstrap method was used to examine the mediation effects.

Results

It showed that: (1) the social exclusion (M = 32.48, SD = 15.25) significantly and …


Effect Of Sodium Carboxymethyl Cellulose Coating Treatment On Oil Absorption In Vacuum-Fried Taro Crisp Strips, Li Xiaoyun, Xie Ronghua, Chen Sheng, Han Chunyang, Chen Junliang, Ren Aiqing, Duan Zhenhua Jun 2025

Effect Of Sodium Carboxymethyl Cellulose Coating Treatment On Oil Absorption In Vacuum-Fried Taro Crisp Strips, Li Xiaoyun, Xie Ronghua, Chen Sheng, Han Chunyang, Chen Junliang, Ren Aiqing, Duan Zhenhua

Food and Machinery

[Objective] Fresh taro was used as the raw material to investigate the effect of sodium carboxymethyl cellulose (CMC -Na) coating combined with blanching,freezing,and osmotic pretreatment on oil absorption in vacuum -fried taro crisp strips.[Methods] The treatments included blanching (CK),blanching +freezing (BF),blanching +freezing +coating (BFC ),blanching +osmotic (BO),and blanching +osmotic +coating (BOC ).The study analyzed their effect on the drying characteristics,hardness,and color of vacuum -fried taro crisp strips,and used low -field nuclear magnetic resonance (LF-NMR ),magnetic resonance imaging (MRI ),and scanning electron microscopy (SEM ) to investigate the oil distribution and microstructure of the taro crisp strips.[Results]] BF treatment increased the …


Pattern Extraction And Design Of Museum Cultural And Creative Food Packaging Based On Shape Grammar, Chang Yan, Cong Huan Jun 2025

Pattern Extraction And Design Of Museum Cultural And Creative Food Packaging Based On Shape Grammar, Chang Yan, Cong Huan

Food and Machinery

To solve the problem of insufficient coupling between pattern extraction and user needs in the innovative design of museum cultural and creative food packaging,a jade animal pattern extraction and design method is proposed based on shape grammar.The animal shapes of Fuhao jades in Yin Dynasty ruins are classified and analyzed,and the Likert five -point scale is utilized to quantitatively analyze the perceptual image.Representative visual elements are then extracted.The core characteristics and combination rules of the patterns are extracted and deduced by combining shape grammar and then transformed into modern design elements to integrate Yin and Shang culture into cultural and …


June 2025, Office Of Sustainability Jun 2025

June 2025, Office Of Sustainability

Office of Sustainability Newsletter

No abstract provided.


Association Of Estimated Plasma Volume Status With Invasive Hemodynamics And All-Cause Mortality In Patients With Liver Cirrhosis, Esteban Kosak Lopez, Phuuwadith Wattanachayakul, Jose Manuel Martinez Manzano, Andrew Geller, Simone Jarrett, John Malin, Raul Leguizamon, Tara John, Rasha Khan, Ian Mclaren, Alexander Prendergast, Kevin Lo, Zurab Azmaiparashvili Jun 2025

Association Of Estimated Plasma Volume Status With Invasive Hemodynamics And All-Cause Mortality In Patients With Liver Cirrhosis, Esteban Kosak Lopez, Phuuwadith Wattanachayakul, Jose Manuel Martinez Manzano, Andrew Geller, Simone Jarrett, John Malin, Raul Leguizamon, Tara John, Rasha Khan, Ian Mclaren, Alexander Prendergast, Kevin Lo, Zurab Azmaiparashvili

Einstein Health Papers

BACKGROUND: Estimated plasma volume status (ePVS) correlates with intravascular congestion and prognosis in patients with heart failure. The ePVS relationship with invasive hemodynamic profiling and clinical outcomes in patients with liver cirrhosis (LC) remains unclear.

METHODS: This single-center retrospective cohort study included LC patients who underwent right heart catheterization (RHC) between 2018 and 2023. Estimated plasma volume status (ePVS) was calculated using the Strauss-derived Duarte formula, with patients classified into high (> 5.5%) and low-ePVS (≤ 5.5%) groups. Cox-multivariable analysis was used to determine if ePVS was associated with all-cause mortality within 1 year post-RHC among transplant-free patients.

RESULTS: Of …


Gomez V. Gomez Jun 2025

Gomez V. Gomez

All Decisions

The court denied the tenant's motion for a stay and undertaking pending an interlocutory appeal of an order denying dismissal of a holdover petition. The court clarified that CPLR 5519(a)(6) automatic stays only apply to judgments or orders requiring enforcement, such as an eviction. Since the appealed order merely denied dismissal and transferred the case to trial, not directing any specific enforcement action against the tenant, an automatic stay was not warranted.


Impact Of An Adapted Diabetes Prevention Program In A Spanish Primary Care Setting: Protocol For A Type Ii Hybrid Effectiveness-Implementation Cluster-Randomized Trial (Aladim), Miquel Bennasar-Veny, Manuela Abbate, Miquel Colom-Rosselló, Laura Capitán-Moyano, Ivonne C Hernández-Bermúdez, Ignacio Ricci-Cabello, Aina M Yañez, Maria E Fernandez Jun 2025

Impact Of An Adapted Diabetes Prevention Program In A Spanish Primary Care Setting: Protocol For A Type Ii Hybrid Effectiveness-Implementation Cluster-Randomized Trial (Aladim), Miquel Bennasar-Veny, Manuela Abbate, Miquel Colom-Rosselló, Laura Capitán-Moyano, Ivonne C Hernández-Bermúdez, Ignacio Ricci-Cabello, Aina M Yañez, Maria E Fernandez

Faculty, Staff and Student Publications

Background: Type 2 diabetes (T2D) is a global health concern affecting 10.5% of the adult population and is projected to rise significantly in the coming decades. Lifestyle modification programs, such as the Diabetes Prevention Program (DPP), can effectively reduce T2D risk among individuals with prediabetes. However, their implementation in real-world healthcare settings remains poor, particularly in Spain, where T2D prevalence is the highest in Europe. The ALADIM study aims to evaluate the effectiveness and implementation of an adapted DPP in Spanish Primary Care Centers (PCCs). The primary effectiveness outcome is weight, the co-primary implementation outcome is implementation fidelity. We will …


Exploring Soft Polymeric Nanoparticles For Targeted Biomolecule Delivery In Plant Cells, Mohammad Rashid Jun 2025

Exploring Soft Polymeric Nanoparticles For Targeted Biomolecule Delivery In Plant Cells, Mohammad Rashid

Theses and Dissertations

Safe and efficient agricultural practices require innovative technologies. Nanotechnology offers promising solutions for advancing plant agriculture by enabling the targeted delivery of biomolecules such as agrochemicals and nucleic acids. This study focuses on developing a safe nanotechnological approach for delivering molecules of interest into plant cells. We investigated the ability of four types of polymeric nanoparticles such as Polyethylene glycol N, Nʹ-dibutylethylenediamine (PEG-DB), Polyethylene glycol 2-pyrrolidin-1-yl-ethyl-amine (PEG-PY), Polyethyleneimine (PEI), Arabinoxylan (AX)+, and Zein+ to form conjugates with plasmid DNA (pDNA). Our findings confirm that plant-derived cationic nanopolymers, AX+ and Zein+, effectively bind negatively charged pDNA (pGFPGUSPlus) carrying a GFP reporter …


Longitudinal Outcomes Of The Covid-19 Pandemic On Youth Physical Fitness, Andjelka Pavlovic, David Leonard, Timothy J Walker, Derek W Craig, Jizyah Injil, Laura F Defina Jun 2025

Longitudinal Outcomes Of The Covid-19 Pandemic On Youth Physical Fitness, Andjelka Pavlovic, David Leonard, Timothy J Walker, Derek W Craig, Jizyah Injil, Laura F Defina

Faculty, Staff and Student Publications

Importance: The COVID-19 pandemic led to a decline in physical activity levels among youths, which could have a negative impact on their fitness.

Objective: To examine longitudinal changes in cardiorespiratory fitness (CRF) and musculoskeletal fitness (MSF) among students at schools participating in a school-based physical activity program during fall 2019 through spring 2023.

Design, setting, and participants: This longitudinal cohort study included US schools reporting CRF and MSF data at least once during the pandemic (fall 2020 to fall 2021) and at least 1 additional time before or after. In a subset of schools for which learning modality data was …


Alternatively Certified Early Childhood Special Education Teachers' Perspectives On Remaining In The Classroom, Sena Victoria Ann Belgard Dever Jun 2025

Alternatively Certified Early Childhood Special Education Teachers' Perspectives On Remaining In The Classroom, Sena Victoria Ann Belgard Dever

Walden Dissertations and Doctoral Studies

Alternative teacher certification programs are used nationwide to address the critical teacher shortage in special education. There is a gap in knowledge regarding the challenges that early childhood special education teachers experience, which make them leave the profession at twice the rate of general education teachers. The purpose of this basic qualitative study was to explore alternatively certified early childhood special education teachers’ perspectives on remaining in their teaching positions and the support they need to continue teaching. The study framework was comprised of Day and Gu’s teacher resilience theory. Data were collected from semistructured interviews with 10 prekindergarten to …


Intouch Week Of June 2, 2025, New York Medical College Jun 2025

Cytarabine Pharmacogenomics And Outcomes Among Children And Young Adults With Acute Myeloid Leukemia., Richard J. Marrero, Vivek M. Shastri, Deedra Nicolet, Krzysztof Mrózek, Christopher J. Walker, William G. Blum, Bayard L. Powell, Jonathan E. Kolitz, Joseph O. Moore, Geoffrey L. Uy, Wendy Stock, Andrew J. Carroll, John C. Byrd, Richard Aplenc, Todd M. Cooper, Alan S. Gamis, Huiyun Wu, Stanley Pounds, Yi-Cheng Wang, Todd A. Alonzo, Soheil Meshinchi, Ann-Kathrin Eisfeld, Edward A. Kolb, Jatinder K. Lamba Jun 2025

Cytarabine Pharmacogenomics And Outcomes Among Children And Young Adults With Acute Myeloid Leukemia., Richard J. Marrero, Vivek M. Shastri, Deedra Nicolet, Krzysztof Mrózek, Christopher J. Walker, William G. Blum, Bayard L. Powell, Jonathan E. Kolitz, Joseph O. Moore, Geoffrey L. Uy, Wendy Stock, Andrew J. Carroll, John C. Byrd, Richard Aplenc, Todd M. Cooper, Alan S. Gamis, Huiyun Wu, Stanley Pounds, Yi-Cheng Wang, Todd A. Alonzo, Soheil Meshinchi, Ann-Kathrin Eisfeld, Edward A. Kolb, Jatinder K. Lamba

Manuscripts, Articles, Book Chapters and Other Papers

IMPORTANCE: Therapeutic responses in acute myeloid leukemia (AML) demonstrate considerable variability both across and within established risk stratifications and age groups. Moreover, significant racial disparities persist, with Black patients experiencing inferior survival outcomes compared with their White counterparts.

OBJECTIVE: To validate the association of the previously reported 10 single nucleotide variant (SNV)-based ara-C pharmacogenomics score (ACS10) with survival outcomes in a large cohort of pediatric AML patients; to evaluate whether ACS10 remains relevant in an adolescent and young adult (AYA) population of patients with AML treated with similar intensive induction chemotherapy protocols; and to assess the association of ACS10 with …


Lived Experiences Of Sex Offenders On Probation With Housing And Employment, Katheryn Winslow Jun 2025

Lived Experiences Of Sex Offenders On Probation With Housing And Employment, Katheryn Winslow

Walden Dissertations and Doctoral Studies

Lived Experiences of Sex Offenders on Probation with Housing and Employment by Katheryn Winslow MA, South University, 2013 BS, University of Central Florida, 2010 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Psychology Walden University May 2025


Association Between Health Insurance, Antiretroviral Treatment, And Hiv Preexposure Prophylaxis In Men Aged 20–85 In Virginia, Lauren Elizabeth Maxwell Jun 2025

Association Between Health Insurance, Antiretroviral Treatment, And Hiv Preexposure Prophylaxis In Men Aged 20–85 In Virginia, Lauren Elizabeth Maxwell

Walden Dissertations and Doctoral Studies

HIV prevention and treatment disparities persist among men in Virginia, particularly in racial and ethnic minority groups. This study examined how insurance type and demographic factors influence prescriptions for antiretroviral treatment (ART) and preexposure prophylaxis (PrEP). Addressing these disparities is critical to advancing public health equity and reducing HIV rates. The purpose was to assess whether age, race, ethnicity, region, and insurance type are associated with the type of oral HIV medication prescribed. Guided by the HIV prevention and care cascade frameworks, the study focused on access and adherence. Using a cross-sectional quantitative design, the study analyzed secondary data from …