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Ping-Chong-Jiang-Ni Formula Effectively Inhibits Migration And Invasion Of Endometriosis 12z Cell Line Via Trip13, Jiahua Peng, Shuzhen Liu, Yunxiang Xie, Min Xiao, Chichiu Wang, Ruining Liang

Journal of Food and Drug Analysis

The Ping-Chong-Jiang-Ni Formula (PCJNF), a compound of Traditional Chinese Medicine (TCM), has demonstrated remarkable clinical effectiveness and is widely utilized in the treatment of endometriosis (EMs). Previous studies have shown that PCJNF inhibits the proliferation and induces the apoptosis of ectopic endometrial stromal cells (EESCs) by modulating the JNK signaling pathway. In our most recent study, published in January 2024, we found that PCJNF effectively alleviates EMs-associated pain by reducing inflammatory mediators, including tumor necrosis factor-alpha (TNF-α) and nerve growth factor (NGF). Furthermore, PCJNF down-

regulates the expression of transient receptor potential vanilloid 1 (TRPV1), phosphorylated TRPV1 (p-TRPV1), and protein …

In Vitro Metabolic Profiling Of Methylenedioxy-Substituted Synthetic Cathinones For Enhanced Detection In Urine Sample Analysis, Ya-Ling Yeh, Chin-Lin Hsieh, Yi-Jia Huang, Yu-Hsiang Chang, Sheng-Meng Wang

Journal of Food and Drug Analysis

Synthetic cathinones are a widely abused class of new psychoactive substances that pose significant challenges in forensic toxicology owing to their complex metabolic pathways and lack of verified reference standards. This study investigated the in vitro metabolism of nine methylenedioxy-substituted synthetic cathinones, including methylone and eight structural isomers, which were categorized into three groups: Group 1 (dimethylone, ethylone, and butylone), Group 2 (dibutylone, pentylone, and eutylone), and Group 3 (N-ethylpentylone and dipentylone). Pooled human liver microsomes, cytosol, and uridine diphosphate glucuronic acid were used to identify phase Ⅰ and Ⅱ metabolites by liquid chromatography–quadrupole time-of-flight mass spectrometry. Key pathways included …

Integrating Network Analysis And Experimental Validation To Reveal The Ferroptosis-Associated Mechanism Of Velvet Antler In The Treatment Of Chronic Atrophic Gastritis, Quan Liao, Zhenzhen Guo, Chenchun Ding, Renjie Zuo, Guoyan Liu

Journal of Food and Drug Analysis

Chronic atrophic gastritis (CAG) is precancerosis with limited treatment options. This study investigated the therapeutic effects of velvet antler (VA), a traditional natural medicine, on CAG, with a focus on ferroptosis. In vivo experiments demonstrated the efficacy of VA in alleviating CAG, and network pharmacology analysis revealed its involvement in related terms, including inflammation, oxidative stress, and cell proliferation. Analyses further confirmed the modulation of ferroptosis by VA, particularly via the Keap1-Nrf2/HO-1/GPX4 pathway. In vitro assays supported these findings, demonstrating the ability of VA to reduce methylnitronitrosoguanidine-induced inflammation, oxidative stress, and ferroptosis in GES-1. This study provides a basis for …

Jiao San Xian Granule Containing Prebiotic Alleviate Functional Dyspepsia By Regulating Intestinal Flora And The Secretion Of Inflammatory Response, Huimin Pei, Mengyuan Zhao, Hongyue Wang, Xindi Zhang, Caihong Shi, Xiangrong Zhang

Journal of Food and Drug Analysis

Jiao Sanxian (JSX) consists of three traditional Chinese medicine including charred hawthorn, malt and Liu Shen Qu, they are also from Chinese medicine homologous food. It is commonly used to relieve functional dyspepsia (FD). The present study aims to explore the mechanism of JSX (granule), with the addition of prebiotics for the treatment of FD using mice model. The network pharmacology and molecular docking were used to forecast therapeutic targets for JSX. Based on the protein-protein interaction (PPI) results, thirteen targets exhibited strong interactions with each other. The results of network pharmacology and molecular docking revealed therapeutic activity of JSX …

Regulatory Framework And Challenges For Live Biotherapeutic Products In Taiwan, Shirley Pan, Jia-Chuan Hsu, Kuo-Teng Hung, Ching-Jung Ho

Journal of Food and Drug Analysis

Products containing live microorganisms may be classified as food or drugs depending on their intended use; live biotherapeutic products (LBPs) with therapeutic claims are defined as medicinal products containing live bacteria or yeasts intended to prevent or treat disease. Based on their characteristics, LBPs are classified as biological drugs and must be registered as biological drugs before they can enter the Taiwanese market. As research into the microbiota and its role in health and disease continues to advance, LBPs are expected to play an increasingly important role in medicine and biotechnology. With the growing popularity of microbial applications in recent …

Aspergillosis: A Comprehensive Review Of Pathogenesis, Drug Resistance, And Emerging Therapeutics, Amanpreet Singh, Jeewanjot Singh, Sandeep Kumar

Journal of Food and Drug Analysis

Aspergillosis stands as a primary opportunistic fungal infection which mainly results from Aspergillus fumigatus events that have gained more importance because of its multiple infection patterns and developing antifungal resistance. Healthcare providers identify two main ends of the aspergillosis spectrum which include allergic responses and invasive systemic infections that affect mainly immunocompromised subjects. This review presents a detailed summary for understanding the epidemiology of aspergillosis along with its risk factors as well as pathogenesis and host immune response and diagnostic difficulties. The analysis puts significant weight on increasing azole and echinocandin resistance that has become worse because of agricultural and …

Psychometric Evaluation Of The Thai Version Of Emotional Labor Scale (T-Els) In Thai Nurses, Vachira Posai, Wisarut Srisintorn, Paramee Thongsuksai, Chanokporn Jitpanya

Journal of Health Research

Background: Nurses often face emotional strain due to emotional labor (EL), which involves concealing or modifying genuine feelings to meet their job requirements. This response can lead to physical, psychological, and behavioral issues. The Emotional Labor Scale (ELS), originally in English, has not been translated into Thai, leaving its psychometric properties unexamined in the Thai context. This study aimed to translate the ELS into Thai and evaluate its psychometric properties among Thai nurses.

Methods: A cross-sectional study design was used. The 14-item scale, which includes surface acting, deep acting, and expression of naturally felt emotions dimensions, was translated using forward …

Predictive Model For Hemoglobin Levels Using Multiple Linear Regression, Dien Gusta Anggraini Nursal, Muhammad Daffa Atthariq Winata, Nohan Arum Romadlona, Noura Rizki, Sabillah Nasitoh, Muhammad Sakhi Baretta

Journal of Health Research

Background: Anemia is a condition in which the number of red blood cells or hemoglobin (Hb) levels fall below normal, limiting the ability of blood to transport oxygen effectively. This study aimed to develop a predictive model for Hb levels by identifying significant risk factors.

Method: This observational analytic study was conducted among 103 randomly selected students of Bung Hatta University in Padang, Indonesia. Data were collected with a questionnaire and a hemoglobin test between April to May 2024. Pearson’s correlation analysis and multiple linear regression were performed in this study.

Results: Bivariate analysis showed significant correlations between Hb levels …

The Prevalence And Prediction Of Uncontrolled Type 2 Diabetes Mellitus In The Lower South Of Thailand, Akemat Wongpairin, Apiradee Lim, Haris Khurram

Journal of Health Research

Background: Type 2 diabetes (T2DM) is a major health issue globally, particularly in middle-income countries. This study assessed the prevalence and factors linked to uncontrolled T2DM and proposed a machine learning model for early prediction in southern Thailand.

Methods: Data from 60,903 T2DM patients (2016–2023) were obtained from Thailand's National Health Data Center. Multiple logistic regression identified associated factors, and machine learning models were compared for prediction.

Results: Uncontrolled T2DM prevalence was 53.5%, highest among patients ≤44 years (69.5%) and in Pattani (61.6%), Satun (58.1%), and Narathiwat (56.7%). Risk factors included being female, younger age, early or long disease duration, …

Predicting Hospitalisation In Older Patients Attended In The Emergency Department Using Classical And Artificial Intelligence Mathematical Strategies, Nere Larrea Aguirre, Susana García Gutiérrez, Oscar Miro, Javier Jacob, Pere Llorens, Guillermo Burillo-Putze, Cesáreo Fernández, Aitor Alquezar-Arbé, Sira Aguiló, Francisco Javier Montero Pérez, José J. Noceda Bermejo, María Teresa Maza Vera, Ángel García García, Patxi Ezponda, Juan González Del Castillo

Journal of Health Research

Background: The ageing population poses a significant challenge for health and social care systems. Emergency Departments (EDs) frequently experience overcrowding due to the high volume of patients and the limited availability of hospital beds. From the perspective of bed management planners, knowing the likelihood of a patient's admission at the earliest stage of care can be highly beneficial for effective resource planning. The goal of our study was to develop a prediction model to identify patients with a high probability of being admitted to the hospital.

Methods: We included all patients aged 65 or older who were treated over …

Factors Predicting Health-Related Quality Of Life Among People With Epilepsy, Thanin Rounratana, Noppawan Phinitkhajorndech, Nipaporn Butsing

Journal of Health Research

Background: Epilepsy is a chronic neurological disease that has a significant influence on individuals' daily activities and health-related quality of life (HRQoL). The HRQoL among people with epilepsy varies depending on several factors. This study aimed to investigate the HRQoL of people with epilepsy and its predicting factors.

Methods: A convenience sampling method was applied to enroll 157 participants with epilepsy who were treated with medication at a tertiary hospital in Bangkok, Thailand, from August 2023 to January 2024. The questionnaires included general characteristics, comorbidities, generalized anxiety disorder (GAD), the International Physical Activity Questionnaire (IPAQ) short form, the Pittsburgh …

Relationships Between Perceptions And Breastfeeding Preparation Behaviors Among Mothers Of Preterm Infants Received Donor Human Milk, Roykrong Kheawlamyong, Jiraporn Punyoo, Tipawan Daramas

Journal of Health Research

Background: Donor human milk (DHM) is a vital nutritional alternative for preterm infants when mothers experience insufficient milk supply during the early postpartum period. However, supporting mothers in producing their own milk remains essential, as it provides specific immunological nutrients for infant health. This study aimed to investigate the relationship between perception factors within the Health Belief Model (HBM) and breastfeeding preparation behaviors among mothers of preterm infants receiving DHM.

Methods: A descriptive correlational study was employed to examine the relationship between perception factors—including perceived susceptibility to and severity of illness, perceived benefits, perceived barriers, and perceived self-efficacy—and breastfeeding preparation …

Individual- And Contextual-Level Factors: A Multilevel Analysis Of Colorectal Cancer Risk In Thai Older Adults, Jiranya Bureemas, Jarin Chindaprasirt, Pongdech Sarakarn

Journal of Health Research

Background: Colorectal cancer (CRC) is a growing public health concern, especially among older adults. In Thailand, CRC risk is influenced by individual and environmental factors. This study investigates the association between individual- and contextual-level factors and CRC risk in Thai older adults.

Methods: A retrospective cohort study included 11,167 adults aged ≥60 years from the Khon Kaen Cohort Study (1990–2001), followed through 2020. CRC cases were histologically confirmed. Multilevel Cox regression estimated hazard ratios (HRs) with 95% confidence intervals (CIs).

Results: Over a median follow-up of 21.7 years, 100 CRC cases were identified. At the individual level, unemployment (HR = …

Renal Function Associated With Mortality Among Patients With Leptospirosis In Upper Southern Thailand: A Hospital-Based Case-Control Study, Lamoon Saengsuwan, Somkiattiyos Woradet, Bhunyabhadh Chaimay

Journal of Health Research

Background: Leptospirosis is a major public health issue in tropical regions. This study investigated the association between renal function and mortality among leptospirosis patients in upper southern Thailand.

Methods: A hospital-based case-control study was conducted on leptospirosis patients from 2012 to 2018. Cases were patients who died, while controls were survivors (1:3 ratio). A total of 42 cases and 126 controls were included. Data were sourced from the Office of Disease Prevention and Control 11, Nakhon Sri Thammarat, and medical records. Key renal function indicators included blood urea nitrogen (BUN), creatinine (Cr), and estimated glomerular filtration rate (eGFR). In-hospital mortality …

Erectile Function And Quality Of Life Among Undergraduate University Students In Almaty, Kazakhstan, Malik Safargaliyev, Denis Vinnikov

Journal of Health Research

Background: Erectile function (EF) in healthy young adults and students is underexplored, as erectile dysfunction (ED) is typically linked to aging. This study aimed to quantify EF in university students and examine its association with quality of life (QL).

Method: This cross-sectional survey was conducted among 1,556 undergraduate students (aged 16 to 22 years; median: 18, IQR: 18–19) at the largest university in Kazakhstan, Almaty. Participants completed a web-based anonymous survey assessing EF using the IIEF-5 and QL using the WHOQOL-BREF. The association between EF and QL was analyzed using multivariate linear regression.

Results: Quality of life (QL) scores were …

Preliminary Validation Of The Thai Version Of The Brief Assessment Of Social Skills In Dementia (Bass-D Th), Pornsinee Laisathit, Chavit Tunvirachaisakul

Journal of Health Research

Background: The Brief Assessment of Social Skills – Dementia (BASS-D) was developed to provide a concise and effective measure of social cognition across four domains. This study aimed to validate the Thai version of BASS-D (BASS-D TH) by examining its psychometric properties and the associated factors.

Method: BASS-D was forward and back-translated between Thai and English language. Minor modifications were made to enhance cultural replicability. The BASS-D TH was administered to 28 older adults without dementia and 13 dementia patients.

Results: Mean age (t=-3.67, p < 0.001), education years (t=2.70, p=0.01) and TMSE score (t=7.49, p< 0.001). The control non-dementia group and dementia group showed mean BASS-D TH total scores of 76.43 (SD = 9.1) and 45.85 (SD = 15.1). The findings demonstrated construct validity of BASS-D TH (group difference t = 8.093, p < 0.001). Correlation with established concurrent tests exhibited concurrent validity, particularly with the face emotion perception and memory of new faces tests, and lower correlations with Theory of Mind. Reliability analyses indicated strong internal consistency (Cronbach’s alpha = 0.807). Receiver Operating Characteristic (ROC) analysis yielded an Area Under the Curve (AUC) of 0.974.

Conclusion: While limited by sample size and the availability of concurrent tests in the Thai …

The Current 'Ban-Demic': School Book Bans In The U.S., Barbara Perez, Jane Caputi

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

This essay examines the alarming rise of U.S book. Our stance is grounded in our experiences as educators and academics in Florida, the state with the highest number of book bans and legislation that has significantly impacted education. Book bans infringe on freedom of expression, right to access information, = students’ right to education, and real harm to targeted communities (i.e., LGBTQIA+ and BIPOC communities), as the bans contribute to the ongoing marginalization and stigmatization of these communities. Diverse representation is key in literature and education. Banning popular culture texts from the classroom stifles critical thinking, social dialogue, and, ultimately, …

Analysis Of The Characteristics Of Lower Limb Muscle Synergy Controlistic Patterns During Unilateral Load-Bearing Walking, Jinwei Zhao, Luyao Chen, Fuyong Liu, Piotr Aschenbrenner, Tomasz Grzywacz, Jan Strawiński

Baltic Journal of Health and Physical Activity

Background: This study aims to investigate how unilateral load-bearing conditions influence lower limb muscle synergistic control patterns during walking. Understanding these patterns is crucial for elucidating the biomechanics of gait under loaded conditions. Materials and Methods: Sixteen healthy adults participated in the study. The Qualisys 600 series motion capture system was used to collect kinematic data, and the Delsys 16-channel wireless surface EMG system to record muscle activity. Four unilateral loading conditions (LL10, LR10, LL20, LR20) were tested, with normal walking as the control. Results: Load-bearing conditions significantly altered muscle contributions in different synergistic units. For example, in Synergistic Unit …

Consumer Choice And Indoor Air Quality, Crystal Jadach

Civil and Environmental Engineering Undergraduate Honors Theses

Outdoor air pollution has drastically improved for everyone since the passage of the clean air act. However, indoor air quality is not monitored or enforceable in the United States. Yet, the EPA estimates that people of developed nations spend approximately 90% of their time indoors. Candles, a common ambiance setting choice for many household consumers, have been well characterized as a source of volatile organic compounds (VOCs). VOCs can have a wide variety of negative effects on human health. A benchtop and pilot scale study were used to characterize the difference in the accumulation and displacement of total volatile organic …

Entropy In Leadership: Reframing Performance Decline As A Failure Of Internal Growth, Joshua M. K. Simmons

M.S. in Leadership

This project explored leadership degradation among mid-to-senior enlisted members (E5–E9) of the United States Air Force using the concept of leadership entropy, the gradual decline of psychological and relational capacity in the absence of sustained support. The topic was selected to address a gap in understanding how internal leadership resilience erodes despite continued performance. A convergent mixed methods design was used, integrating quantitative survey constructs such as burnout, psychological capital, and perceived organizational support with open-ended narrative responses. Twenty-four participants contributed data. Results showed that while leaders remain outwardly effective, internal motivation and connection often deteriorate over time, especially at …

Versatile Imidazole Scaffold With Potent Activity Against Multiple Apicomplexan Parasites, Monique Khim, Jemma Montgomery, Mariana Laureano De Souza, Melvin Delvillar, Lyssa J. Weible, Mayuri Prabakaran, Matthew A. Hulverson, Tyler Eck, Rammohan Y. Bheemanabonia, P. Holland Alday, David P. Rotella, J. Stone Doggett, Bart L. Staker, Kayode K. Ojo, Purnima Bhanot

Department of Chemistry and Biochemistry Faculty Scholarship and Creative Works

Malaria, toxoplasmosis, and cryptosporidiosis are caused by apicomplexan parasites Plasmodium spp., Toxoplasma gondii, and Cryptosporidium parvum, respectively, and pose major health challenges. Their therapies are inadequate, ineffective or threatened by drug resistance. The development of novel drugs against them requires innovative and resource-efficient strategies. We exploited the kinome conservation of these parasites to determine the cellular targets and effects of two Plasmodium falciparum inhibitors in T. gondii and C. parvum. The imidazoles, (R)-RY-1-165 and (R)-RY-1-185, were developed to target the cGMP dependent protein kinase of P. falciparum (PfPKG), orthologs of which are present in T. gondii and C. parvum. Using …

The Effects Of Race And Ethnicity On School Connectedness And Academic Outcomes Among Adolescents, Hafsa Khan Owens

College of Science and Health Theses and Dissertations

This study examines the role of school connectedness and how racial/ethnic identity in academic outcomes among adolescents/. Guided by the self-determination theory (Ryan & Deci, 2017) and Garcia-Coll et al’s (1996) Integrative Model, it was hypothesized that higher school connectedness predicts higher GPAs, that students whose racial/ethnic identity aligns with their schools’ majority composition experience stronger school connectedness, and the relationship between school connectedness and GPA will be stronger in schools with more matching peers. Participants included 138 youth (M = 14.98, SD = 1.92) from three urban schools (two K-8th; one high school). The sample was 33.3% Hispanic, 23.9% …

Criminalization Of Homelessness: The Impact Of A Market-Oriented Approach, Gabriella M. Chioffi

Duke Journal of Comparative & International Law

Since the fourteenth century, countries have sought to criminalize unhoused individuals by labeling them as "vagrants." Currently, the United States and other countries continue to criminalize acts of sleeping rough, begging, loitering and other vagrancy-type activities that disproportionately target unhoused persons. Despite going through a period of decriminalization in the 1960s and 1970s, these punitive measures were largely reinstated by the 1990s. In the most extreme case, vagrancy criminalization was entrenched in a state's constitution. This Note contends that the reversion to punitive measures is triggered by a country's transition to a market-oriented approach that privatizes housing development and de-emphasizes …

Collaboration Across The Silos: Consultation As A Means For Integrating Services For Twice-Exceptional Learners, Kimberly Bowers Yoshino

Electronic Theses and Dissertations

Twice-exceptional (2e) learners are underserved in American schools. As students who demonstrate both giftedness and disabilities, 2e learners maintain profiles that warrant tailored educational services across special and gifted education programs. Yet, these programs are considered institutionally mutually exclusive as legal mandates create de facto isolation — the antithesis of what is recommended for the students’ optimal development. School psychologists have been identified as professionals critically positioned to support 2e learners because of their specialized skill set, namely in consultation. However, little is known about their consultative practices with the educators who serve 2e learners or how they traverse school …

Young Adults’ Metaperceptions Of Their Childhood Caregivers’ Appraisals And Young Adulthood Mental Health, Cassandra Svelnys

Electronic Theses and Dissertations

Early experiences and relationships have enduring impacts on the development of self and later mental health and wellbeing. In social relationships and interactions, the developing individual is continuously assessing how they view themself, how they view the other person, and how they believe the other person views them. Metaperceptions represent the latter construct: how an individual thinks another person perceives them. Childhood self-esteem, parent-child attachment, and metaperceptions are foundational constructs for the developing individual, yet metaperceptions have not previously been tested as a predictor for adulthood mental health while also accounting for childhood self-esteem and parent-child attachment. This study introduced …

Who Gets To Be A Child And When? The Pervasive Yet Contextually Shaped Nature Of Racialized Adultification Across Perceivers And Contexts, Kevin M. Summers

Electronic Theses and Dissertations

Racialized adultification is a pervasive bias in which individuals tend to judge Black children as older and more adult-like than White children of the same age. This racial bias is discussed across many scientific domains in addition to popular media, yet there is relatively little empirical work documenting its existence, consequences, and boundary conditions. In the current work, I aim to develop an empirical foundation that advances scientific understanding of racialized adultification and in turn contributes to a growing model that elucidates the conditions under which individuals are disproportionately likely to express this pernicious bias. In the current work, I …

Employee Engagement Strategies For Purchasing Managers, Winona L. Sewell Hall

Walden Dissertations and Doctoral Studies

The lack of employee engagement negatively impacts organizations through revenue loss, poor productivity, and toxic cultures. Purchasing managers are concerned with decreased employee engagement as it negatively impacts productivity and revenue. Grounded in situational leadership theory, the purpose of this qualitative pragmatic inquiry was to explore strategies purchasing managers use to increase engagement and productivity. The participants were six managers who have been successful in implementing strategies to increase employee engagement. Data were collected using semistructured interviews. Through thematic analysis, three key themes were identified: (a) communication, (b) leadership styles, and (c) culture. A key recommendation is for purchasing managers …

Management Of Embedded Unexploded Ordnance In Low-Resource Settings: A Scoping Review, Eric S. Weinstein, David Nitsch, Chris Leboa, S. Yves G. Sanou, Yves Aziz Nacanabo, Serhii Tertyshnyii, Amila Ratnayake, Akul Gupta, David T. Walker, Paul Amoroso, Barclay Stewart, Hannah Wild

College of Health Professions Faculty Papers

OBJECTIVES: When unexploded ordnance (UXO) is embedded in the body, the effect of explosive weapons used in conflict is amplified. Though relatively rare, such events present potentially devastating consequences for the patient and medical providers as routine diagnostic and therapeutic procedures hold potential to initiate detonation of the embedded UXO (eUXO). The objective is to identify and synthesize available literature relating to the management of eUXO in low resource settings.

METHODS: A scoping review was conducted using PRISMA-ScR methodology to evaluate literature in all languages from all date ranges until January 31, 2024, discussing the management of casualties with eUXO, …

Advances In Bone And Orthopedics 2025 – 5th Edition, Jean-Philippe Berteau, Laurent Pujo-Menjouet, Hélène Follet, Aurélie Levillain

Publications and Research

This volume brings together selected works from the 2025 Bone and Orthopedics Interdisciplinary Symposium (BONITOS), underscoring our community’s ongoing commitment to advancing research in biomechanics, bone health, and orthopedic science. The symposium unites leading experts from around the world, fostering collaboration and the exchange of ideas across disciplines. Organized in partnership with the French-speaking Society of Biomechanics, the French National Institute of Health and Medical Research (INSERM), the University of Lyon, the College of Staten Island of the City University of New York (CUNY), and the American Association of Physical Therapists (APTA) – Brooklyn Staten Island Chapter, BONITOS 2025 represents …

Photochemistry Of Quinones And Combustion-Derived Particles, Desiree J. Sarmiento

Electronic Theses and Dissertations

Quinones are ubiquitous species that can be produced from the photochemical aging of combustion-derived particles (CDPs). Polycyclic aromatic hydrocarbons (PAHs) are a major component of CDPs and are precursors to quinones and other oxidized products (OPAHs). My work first expanded on the PAH and OPAH photochemistry research of Dr. John Haynes, who showed that anthracene (ANT) oxidizes into 1,4-naphthoquinone (1,4-NAPQ), 1,4-anthraquinone (1,4-ANTQ), and 9,10-anthraquinone (9,10-ANTQ), and of Dr. Heather Runberg, who demonstrated the ability of ANT and these quinones to generate reactive oxygen species (ROS). Then at the Pacific Northwest National Laboratory (PNNL), I was given the opportunity to investigate …