Digital Commons Network^™

The Role Of Adolescent Depression Heterogeneity And Resilience Resources In Adulthood Cardiometabolic Health And Depressive Symptoms, Samantha R. Scott

Electronic Theses and Dissertations

Depression in adolescence is a major public health problem and is a risk factor for early-onset cardiometabolic disease. Although adolescent depression is a risk factor for poor cardiometabolic health, depression is heterogeneous and associations may differ by sex. Additionally, if risk factors such as depression can predict adulthood cardiometabolic health, resilience factors (e.g., social, school, neighborhood) that are protective for depression may also be protective for physical health, but this is an ongoing area of research. The goals of the current dissertation were to gain a better understanding of what depressive symptom presentations in adolescents are most concerning for adulthood …

A Qualitative Examination Of Homelessness Risk Factors And Housing Histories Of Single Room Occupancy (Sro) Tenants In Chicago, Shadman Syed Saquib

College of Science and Health Theses and Dissertations

Single-Room Occupancy (SRO) housing is among the most affordable private market housing options and serves tenants who often have multiple oppressed identities, including economic marginalization, carceral histories, and disabling conditions. However, SRO buildings are often sold for redevelopment, displacing tenants with few alternative housing options and at risk of homelessness. Research suggests that multiple ecological factors, such as prior housing instability, predict future homelessness, which may be compounded for individuals with oppressed identities. Thus, the current study explores the housing histories and identities of displaced SRO tenants to understand their vulnerability to post-displacement homelessness. Seventeen participants who were displaced from …

Dataset For Cholesterol And Q147e Deamidation Modulates Aa-Crystallin Membrane Binding Elucidating Protective Role Of Lens Membrane Composition Changes With Aging, Preston Hazen, Nawal K. Khadka, Laxman Mainali

Biophysics Research Data

Purpose: αA-Crystallin (αAc) binding with lens membranes increases with age and cataract formation. However, the role of lipids and cholesterol (Chol) in Q147E-αAc membrane binding remains unclear, which we aim to elucidate in this study.

Methods: We have used the electron paramagnetic resonance spin-labeling method to probe the Chol/ 1-palmitoyl-2-oleoylphosphatidylcholine (POPC) and Chol/ sphingomyelin (SM) membranes binding with wild-type (WT) and Q147E-αAc.

Results: Compared to WT-αAc, the Q147E mutant had increased binding to POPC and decreased binding to SM membranes without Chol. Adding 33 mol% Chol to the POPC and SM membranes decreased the binding of WT and, to a …

Design, Manufacturing, And Engineering Design Validation Of A Fetal Activity Monitor, Hector Andres Pena Vega

Undergraduate Honors Theses

Fetal movement monitoring is an important indicator of fetal health, but

current methods often rely on subjective self-reporting or medical equipment that

may not be universally available. The research described in this thesis describes

the design, manufacture, and engineering validation of a wearable fetal activity

monitor based on nanocomposite wide-range strain gauge technology. Embedded

in a wearable maternity band garment, the technology is designed to discreetly

record fetal movements with the eventual goal of providing real-time information

that can assist pregnant women and medical professionals in monitoring patterns

of fetal activity.

The scope of the described research focuses on the …

Synthesis Of Anti-Schistosomal Heterocyclic Compounds Targeting Thioredoxin Glutathione Reductase, Alexander Stewart

Lawrence University Honors Projects

chistosomiasis is a deadly and debilitating parasitic disease caused by Schistosoma mansoni which affects 200+ million people annually who come into contact with contaminated water. Currently only one drug (Praziquantel) has been used to treat this disease for almost 50 years, and fear of resistance is growing, thus a new drug and new target is needed. Inhibition of the organism-specific redox defense protein Thioredoxin Glutathione Reductase (TGR) has lead to the death of the worm in vitro, indicating that it would be a good druggable target. Fragment based analysis and x-ray crystallography have returned the outline of a lead compound …

Burned In Berlin – Banned In Boston: Censorship Of Booksellers During The Interwar Period In The U. S. As Compared To Germany, 1919-1939, Aleksandra Jimerson-Mckinnies

Lawrence University Honors Projects

During the twenty-year interwar period from 1919-1939, two vastly different nations faced their own personal wars with the censorship of booksellers. Germany—at first the Weimar Republic, then later the Nazi Regime—underwent such a transformation that Berlin went from one of the literary capitals of the world to the site of the most infamous of censorship crimes: the book burnings. Meanwhile, the United States was a long-standing democratic nation in which freedom of speech was one of its cornerstone tenants. Despite the differences of governments and the scope and scale of the censorship, there were major similarities between the tactics and …

4th Sbs International Conference 2025: Transforming Business For People And Planet, School Of Business Studies (Sbs)

Conference Proceedings

The IBA-SBS International Conference (IBA-SBSIC) brings together scholars, professionals, and policymakers from around the world, providing a platform for learning, collaboration, and cutting-edge research. As we enter the 4th edition in 2025, the conference embraces the theme "Transforming Business for People and Planet."

The business landscape is evolving rapidly, with companies increasingly held accountable for their environmental footprint, ethical responsibilities, and social impact. Governments, regulators, and consumers now demand responsible business practices that align with sustainability and long-term financial resilience. Sustainability is no longer a choice—it is a necessity. Global movements toward climate action, social equity, and responsible governance are …

Abstract 2587 Recombinant Expression And Purification Of A. Vinelandii Cown In E. Coli, Julie Takei, Cedric P. Owens, Katie Sanders, Neeraja Gajendran

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The goal of this project is to study the protein CowN in the diazotroph Azotobacter vinelandii (Av) in comparison to CowN in Gluconacetobacter diazotrophicus (Gd). Nitrogenase is an enzyme that catalyzes the reduction of nitrogen gas into ammonia in diazotrophic bacteria. In many diazotrophs, the protein CowN prevents nitrogenase inhibition from the environmental gas carbon monoxide (CO). Previous work studied CowN in the diazotroph G. diazotrophicus. In G. diazotrophicus, CowN binds to nitrogenase and weakens CO binding to its active site. The mechanism of CowN has only been investigated in G. diazotrophicus. Thus, we are interested in determining if CowN's …

Status Of Persistent Organic Pollutant Of Brominated Flame Retardant Hbcd In Daily Diet And Its Potential Health Risks, Zhao Zirui, Ji Hainan, Zhao Chan, Shen Guolin, Zhang Mengling

Food and Machinery

Hexabromocyclododecane (HBCD ) is a brominated flame retardant widely used in flame retardant for various industrial and consumer products.Due to its high biotoxicity,bioaccumulation,pollution persistence,and long -range transport capacity,HBCD has been included in the Stockholm Convention list of persistent organic pollutants (POPs ) and is being phased out globally.In this paper,the contamination of HBCD,additive brominated flame retardants,in daily diet and the characteristics of HBCD absorption and metabolism in the body are briefly described.Then,the evaluation of HBCD exposure toxicity by bioinformatics,in vitro primary cell models,and cell line models are reviewed.Subsequently,the effects of HBCD intervention on the toxicology of zebrafish models,mouse models,and rat …

Exploration On Hypoglycemic Mechanism Of Components In Guangdong Finger Citron Based On Network Pharmacology And Molecular Docking, Ma Wencong, Wu Yuxiao, Zhong Cheng, Zhou Aimei

Food and Machinery

［Objective］ To study the potential targets of hypoglycemic effects of components in Guangdong Finger Citron (GFC ) based on network pharmacology.［Methods］ Genes associated with type 2 diabetes mellitus (T2DM) and hyperglycemia are screened using the TTD,DrugBank,OMIM,and DisGeNET databases.Active components of GFC are collected from literature,and potential targets are predicted using the Swiss database.Based on this,key proteins are then identified through the STRING database,and a "disease -active -component -target -pathway" network was constructed using Cytoscape 3.7.1.Functional annotation is further carried out by performing gene ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG ) pathway enrichment analyses through the …

Stability And Sensory Evaluation Of Capsaicin Emulsion Based On Oil Unsaturation Degrees, Fan Xinying, Su Wei, Wang Xinmiao, Chen Jianshe, Hu Xiaoxue

Food and Machinery

［Objective］ To investigate the effect of oil phase unsaturation degree on the performance of capsaicin emulsion to optimize its application efficacy in food systems.［Methods］ Flaxseed oil (α-linolenic acid ),sunflower oil (linoleic acid ),and camellia oil (oleic acid ) are selected to construct the emulsion systems.The particle size distribution,zeta potential,microstructure,in vitro digestion stability,and sensory characteristics are systematically analyzed.［Results］ The camellia oil emulsion exhibits the largest value in average particle size of specific surface area,while the flaxseed oil emulsion demonstrates the smallest particle size and significantly higher absolute zeta potential values (P<0.01).Its compact interfacial structure maintains smaller particle sizes throughout the digestion process (P<0.01),ensuring the optimal protection of capsaicin.According to sensory evaluation,the flaxseed oil emulsion has the strongest spicy perception,potentially attributed to its high unsaturation degree.［Conclusion］ The findings demonstrated that the stability of capsaicin emulsions correlates with the unsaturation degree of the oil phase.Highly unsaturated fatty acids enhance emulsion stability by forming viscoelastic interfacial films.Flaxseed oil,with the highest unsaturation degree,produces emulsion with the smallest particle size,most uniform distribution,and best emulsion stability and pungency intensity.

Uncertainty Evaluation For Cs- 137 In Food By Low-Background Α/Β Counter, Sun Gongming, Li Guanchao, Huang Lingyu, Li Qiaoqin, Li Meili

Food and Machinery

［Objective］ To improve the measurement accuracy of cesium -137 (Cs-137) content in food using low -background α/β measuring instruments.［Methods］ An uncertainty analysis model for measuring Cs -137 in food was established based on the second method in GB 14883.10-2016.The uncertainty components affecting the detection process were analyzed,the sources of uncertainty were explored,and the uncertainty was evaluated.［Results］ Through uncertainty analysis introduced by sample measurement,supervised source measurement,cesium recovery rate calibration,sample sampling,sample ash -to-fresh ratio,standard source calibration supervised source,and self -absorption coefficient calibration,the activity concentration of Cs -137 in food determined by the ammonium phosphomolybdate method was 1.44 Bq/kg,with an expanded uncertainty of …

Determination Of Six Human Milk Oligosaccharides In Infant Formula Milk Powder By Ion Chromatography, Zhang Jiaqi, Li Yunxuan, Wang Lulu, Zhang Shuifeng, Pan Xiangjie, Shi Yuanxu, Que Liming

Food and Machinery

［Objective］ To establish an ion chromatography method for the simultaneous determination of six human milk oligosaccharides (HMOs ) in infant formula powder.［Methods］ The samples were enzymatically hydrolyzed using fructanase.Gradient elution was performed with a mobile phase consisting of water,0.5 mol/L sodium hydroxide,and 0.3 mol/L sodium acetate.Separation was carried out on a Thermo Fisher CarboPac ™ PA1 Analytical Column,and detection was performed using ion chromatography with pulsed amperometric detection.［Results］ In milk powder,2'-fucosyllactose (2'-FL),3-fucosyllactose (3-FL),and lacto -N-tetraose (LNT ) showed good linearity within the range of 1~100 mg/L,while lacto -N-neotetraose (LNnT ),3'-sialyllactose (3'-SL),and 6'-sialyllactose (6'-SL) exhibited good linearity in the range of …

Effect Of Electric Steamer Steaming Parameters On The Cooking Quality Of Eggplant, Zhao Wenyu, Xu Yanshun, Li Yujing, Fang Kun, Yao Qing, He Xiaoyan

Food and Machinery

［Objective］ To evaluate the cooking quality of food based on its color characteristics.［Methods］ Using heating curves,color measurements,and anthocyanin content as evaluation indexes,the effect of steaming power,anaerobic environment,surface temperature change of eggplant,and steaming volume on the color of eggplant was investigated.［Results］ Eggplants steamed in a steamer pot had significantly better color compared to those steamed in a steam oven.The steaming power,volume,anaerobic environment,and surface temperature of the eggplant all affected its color and anthocyanin loss rate.As the steaming power increased and the steaming volume decreased,the anthocyanin loss rate decreased.The lowest anthocyanin loss rate of 44.27% occurred when the steaming power was 2 …

Effects Of Repeated Freezing-Thawing On Physicochemical Properties And Quality Of Freshwater Silver Carp Bladder, Huang Darong, Feng Rui, Zhong Biluan, Tian Jianxin, Liang Jiehua, Zhang Yu

Food and Machinery

［Objective］ To investigate the effects of different freezing and thawing cycles on the physicochemical properties and quality of silver carp fish bladder.［Methods］ Fresh silver carp fish bladder was used as the research material.The trends of water retention,color difference,textural properties,basic nutrient content,and microstructure of the fish bladder were analyzed under different freezing -thawing cycles.［Results］ As the number of freeze -thaw cycles increased,the cooking swelling rate,brightness value,yellowness value,hardness,cohesion,adhesiveness,collagen content,and total protein content of the silver carp fish bladder all decreased significantly (P<0.05),with reductions of 45.52%,10.90%,48.99%,47.45%,13.56%,58.04%,10.54%,and 4.57%,respectively.The decreases in moisture,fat,and ash content were relatively low.The thawing loss rate and color redness value both increased significantly (P<0.05),by 4.80% and 140.72%,respectively.The microstructure of the silver carp fish bladder gradually deteriorated and broke down during the repeated freezing -thawing process.［Conclusion］ Based on the quality deterioration during the comprehensive freezing -thawing process,limiting the freezing -thawing cycles to no more than five can effectively preserve the characteristics and quality of the silver carp fish bladder.

In Vitro Digestion Characteristics Of Steam-Exploded Oats And Their Effects On Obesity Induced By High-Fat Diet In Mice, Wang Jing, Kuang Chuyu, Xia Zhihui, Cai Jiaru, Wang Xufeng, Luo Kaiyun

Food and Machinery

［Objective］ To investigate the effects of steam explosion pretreatment on the microstructure of oats,the content of β-glucan,the digestion characteristics of starch,and its effect on obesity in mice fed a high -fat diet.［Methods］ The effects of steam explosion treatment under different pressures (0.3,0.5 MPa ) and time (30,60,90 s) on the microstructure of oats and the composition of β-glucan are investigated,and the obesity inhibitory effect of steam -exploded oats in a simulated high -fat diet environment is studied.［Results］ Steam explosion can destroy the ordered structure of the oat cell wall,increase the content of slowly digestible starch,the content and dissolution rate of …

Thermal Rheological Properties Of Heat-Moisture Modified And Its Application In Multigrain Cookies, Thi Huyen Trang, Li Xianghong, Miao Jinxu, Wang Faxiang, Liu Yongle, Li Shuang

Food and Machinery

［Objective］ To develop low -burden,high -nutrient functional baked foods.［Methods］ A single -factor experimental design is employed,with rapid visco analyzer,rheometer,and differential scanning calorimeter to analyze the physicochemical properties of heat -moisture modified wheat flour.The cookie formula is optimized based on sensory evaluation.［Results］ Heat -moisture treatment significantly enhances the pasting stability and resistant starch content of wheat flour.The optimal auxiliary ingredient formula is 50 g of heat-moisture modified wheat flour,20 g of oat flour,10 g of mung bean flour,and 6 g of resistant dextrin powder.Compared with the control group,the cookies made from the experimental formula show a significantly lower digestibility,with a glycemic …

Optimization Of The Process Of Korean Pine Seed Oil Enzymatic Degumming By Ultrasound-Assisted Method And Its Antioxidant Activity, Qu Yanfeng, Xiang Lan, Chen Tianpeng, Zhang Zhe, Jia Yunzhe, Zhang Hanbing

Food and Machinery

［Objective］ To reduce the phosphorus content in Korean pine seed oil and develop an efficient degumming method.［Methods］ An ultrasound -assisted method was used,and the degumming process of Korean pine seed oil was optimized through orthogonal experiments.The fatty acid composition,content,and antioxidant capacity of the degummed oil were analyzed.［Results］ The optimal degumming conditions for Korean pine seed oil were ultrasonic power of 420 W,degumming temperature of 50 ℃,degumming time of 3.5 h,enzyme dosage of 40 mg/kg,and pH 4.8.Under these conditions,the phosphorus content of the degummed oil was (5.18 ± 0.24) mg/kg,and the proportion of pinolenic acid in total fatty acids was 15.46%.When …

Extraction Of Cereal Polyphenols And Their Application In Aquatic Products, Wen Shuyao, Yao Yile, Ye Linlin, Deng Na, Zhang Bo, Li Hui, Wang Jianhui

Food and Machinery

Cereal polyphenols mainly exist in free or bound states,including two major categories:phenolic acids and flavonoids.Their contents are affected by factors including cereal varieties,germination conditions,processing methods,and storage conditions.The extraction methods of cereal polyphenols are mainly acid,alkali,enzymatic hydrolysis,and supercritical fluid extraction methods.This paper reviews factors affecting the cereal polyphenol types,extraction methods,contents,and titers.Additionally,this paper looks forward to their application in aquatic product preservation.

Research Progress On Deep Eutectic Solvents In Extraction Of Polysaccharides From Edible Mushrooms, Pei Longying, Liu Wei, Wang Sidan, Wang Xiaoyu, Zhou Yuting, Xie Chaoying

Food and Machinery

Polysaccharides in edible mushrooms possess biological activities such as immunomodulation,antioxidant effects,anticancer properties,and regulation of intestinal microbiota.Deep eutectic solvent (DES ) extraction has gained attention as a novel method for polysaccharide extraction.This article outlines the composition,synthesis methods,and important properties of DES,summarizes and discusses research on polysaccharide extraction from edible mushrooms using DES in China and abroad,and further explores the limitations of the DES extraction method.

Research Progress On Extraction And Biological Activity Of Corn Silk Polysaccharides, Xu Xiuying, Wen Liankui, He Yang, Yu Lei

Food and Machinery

Corn silk,the dried style and stigma of corn,is a traditional Chinese herbal medicine and functional food ingredient.Polysaccharides,one of the main bioactive components of corn silk,exhibit hypoglycemic,hypolipidemic,antibacterial,and anti -inflammatory effects.This article reviews the extraction methods and biological activities of corn silk polysaccharides,summarizing the process parameters,advantages,and disadvantages of different extraction methods,as well as the biological activities and mechanisms of action of corn silk polysaccharides,which are current research hotspots.

Advances In Immunoassay Methods For Quinolones, Wu Mengjiao, Li Ning, Hu Mei, Xu Yan, Wang Jie, Xiang Feng

Food and Machinery

Quinolones (QNs ) are highly favored for their broad -spectrum antibacterial effects.However,the overuse of QNs in animal feed can lead to their residues entering the food chain,thus posing potential hazards to the environment and human health.This paper summarizes the main immunoassay techniques for quinolone residues,analyzes their advantages and application prospects,and discusses the challenges and future development directions of immunoassay techniques.

Research Progress On The Protective Effect And Mechanism Of Inulin Against Liver Injury, Yun Hang, Guo Yifan, Wang Peiwen, Xu Yanrui

Food and Machinery

Liver injury is caused by one or more factors acting on the liver,damaging liver cells and resulting in pathological changes in the liver,as well as elevated serum transaminases.In severe cases,it may lead to liver failure and hepatic encephalopathy.Inulin is a common dietary fiber with various biological activities,including anti -inflammatory,antioxidant,anti -cancer properties,and the regulation of gut microbiota.These biological activities are closely related to the protection of liver health.This article reviews the protective effects of inulin against various types of liver injury,summarizes the mechanisms underlying its protective effects on the liver,and looks forward to future research directions.

Dark Tourism And ‘Partial Religiosity’: Ontological-Aesthetic Pilgrimage In Camiguin Island, Philippines, Jan Gresil Kahambing

International Journal of Religious Tourism and Pilgrimage

This paper theorizes the contrast between dark tourism and what is referred to as ‘partial religiosity’ in the context of travel to selected tourist destinations on Camiguin Island, Philippines. Also called ‘thanatourism’, dark tourism is about visiting places that challenge the value derived from the association with death either from tragedies of naturally occurring catastrophes (such as earthquakes, volcanic eruptions, or typhoons) or disasters produced by humans (such as genocides and violations of human rights). Focus is on three spots that sufficiently fit the description of dark tourist sites in Camiguin in the sense of naturally-caused disasters, namely: the Sunken …

The Museum Of The City: A Case Study Of Self-Guided Site Visits For Built Environment Education, Elaine Edmonds

Irish Journal of Academic Practice

This case study examines the development and implementation of a self-guided, museum style site visit project for built environment students, created in response to the logistical and pedagogical limitations exacerbated by the Covid-19 pandemic. Drawing on principles of Universal Design for Learning (UDL), the project Museum of the City integrates narrative-based microlectures, multimodal media, and optional reflective activities to support student engagement and accessibility. Over four years of integration into a final-year planning module, the approach has demonstrated sustained student participation, adaptability across delivery modes, and pedagogical value in contextualizing theoretical content. This case study outlines the rationale, design process, …

Police Reform Advocacy And The Emergence Of The Seattle Black Panthers, Hayden Young

Lawrence University Honors Projects

This honors project examines the factors which led to the emergence of the Seattle chapter of the Black Panther Party (BPP) in 1968, with a focus on one of the BPP’s signature issues — police reform. Negative perceptions of the Seattle PD, especially among the city’s rapidly growing population of Black residents, led Mayor Allan Pomeroy to form a citizen’s committee titled “the Mayor’s Advisory Committee on Police Practices” (MACPP) in 1955. The MACPP recommended the formation of a civilian-led police oversight board in its 1956 final report, and civil rights groups such as the Urban League, ACLU, and NAACP …

Simple Yet Effective, Effective Yet Inclusive: A Skincare Line, Ayesha Wali Rahimoon

Lawrence University Honors Projects

This honors project addresses the lack of inclusive skincare formulations by developing a scientifically grounded skincare line with an antioxidant-rich serum, moisturizer, and cleanser tailored to support diverse skin types, particularly melanin-rich skin. The serum combines strawberry extract powder, Manuka honey, niacinamide, green tea extract, and humectants to promote hydration, antioxidant protection, and skin barrier reinforcement. Formulated with a stable pH of 5.0–5.5 and an effective preservative system, the product was tested through non-animal, biologically relevant models.

A UV protection assay using HEK293 cells demonstrated that the serum significantly reduces oxidative damage, increasing post-exposure cell viability to 80%, compared to …

“Why Us, Though?” Gendered Resilience In Climate-Displaced Bangladesh Narrated By Child Brides, Marzuka Amal Binthe Akber

Lawrence University Honors Projects

This thesis explores the resilience strategies narrated by women and girls displaced by climate change and subjected to child marriage in Bangladesh. Centering their voices and lived experiences, it highlights the intricate, often invisible methods through which these women navigate the intersectional precarity of environmental displacement, gender norms, and socio-economic marginalization. Through qualitative fieldwork conducted in riverine islands (chars), urban informal settlements, and government resettlement sites, the study foregrounds community practices like adda (social storytelling), mutual caregiving, informal healthcare, bodily negotiations, and strategic silence. Challenging dominant narratives of passive victimhood, it reveals resilience as relational, iterative, and context-specific acts rooted …

Hormonal Modulation Of Perineuronal Net Density In The Female Peromyscus Californicus Hippocampus And Medial Prefrontal Cortex, Nazlee Harunani

Lawrence University Honors Projects

Perineuronal nets (PNNs) are specialized extracellular matrix structures that regulate synaptic plasticity and stabilize neural circuits, particularly during the closure of critical periods, a time when the brain is highly plastic and susceptible to environmental influence. Emerging evidence suggests that PNNs may be sensitive to hormonal fluctuations associated with critical periods such as puberty and pregnancy, yet their role in the female brain, particularly in relation to other well-characterized hormonally-mediated events, remains underexplored. This project investigated whether PNN expression in the hippocampus and medial prefrontal cortex varied following vaginal opening, or across different stages of the estrous cycle in Peromyscus …

Marie Lamb V. Cvs Pharmacy Llc

2025 Decisions

USDC for the Eastern District of Pennsylvania