Digital Commons Network^™

Advances In Molecular Imaging For Neuroendocrine Neoplasms, Bradley Girod, Vikas Prasad

2020-Current year OA Pubs

Neuroendocrine neoplasms (NENs) represent a heterogenous group of tumors with significant inter- and intra-patient variability. Once considered to be rare, neuroendocrine neoplasms are being increasingly recognized through the advent of advanced diagnostic techniques, which may be contributing to the significant increase in the incidence and detection rate of these tumors. NENs can be classified into well differentiated and poorly differentiated neuroendocrine tumors (NETs) or neuroendocrine carcinomas (NECs). The proliferation rate of NETs can vary from Ki-67 1-55%. In addition, the SSTR expression can vary significantly. Because of this high "heterogeneity", their detection and characterization have become essential to disease management, …

Sars-Cov-2 Nsp15 Enhances Viral Virulence By Subverting Host Antiviral Defenses, Allen Caobi, Tamarand L Darling, Adrianus C M Boon, Et Al.

2020-Current year OA Pubs

SARS-CoV-2 encodes numerous virulence factors, yet their precise mechanisms of action remain unknown. We provide evidence that the SARS-CoV-2 nonstructural protein 15 (nsp15) enhances viral virulence by suppressing the production of viral double-stranded (dsRNA), a potent inducer of antiviral signaling. The viral variants lacking nsp15 endoribonuclease activity elicited higher innate immune responses and exhibited reduced replication in human stem cell-derived lung alveolar type II epithelial cells, as well as in the lungs of infected hamsters. Consistently, these variants caused significantly less weight loss and mortality compared to wild-type (WT) virus in K18-hACE2 mice. Mechanistically, the cells infected with nsp15 mutants …

The Corporate Governance Of The Biggest Corporations You’Ve Never Heard Of, Aaron M. Schutt

Alaska Law Review

When Congress passed the Alaska Native Claims Settlement Act (ANCSA) in 1971, it directed the creation of twelve regional and over two hundred village corporations chartered under Alaska state law. ANCSA subjected these corporations to Alaska’s corporate governance framework, including the laws and regulations governing corporate elections. This Article examines the statutory and regulatory requirements applicable to ANCSA corporations, including the various requirements around ANCSA corporation annual shareholder meetings. It also analyzes relevant state and federal case law interpreting and applying these requirements. Finally, the Article explores the rights and responsibilities of corporate directors and officers, as well as the …

Rediscovering Alaska’S Right To Housing, Helen Malley

Alaska Law Review

In the wake of Grants Pass v. Johnson, state constitutions provide an alternative avenue to protect the rights of people experiencing homelessness. While some states contemplate amending their constitutions to encompass a right to housing, this Article argues that such a right already exists in the Alaska Constitution. Article VII, Sections 4 and 5 explicitly direct the legislature to provide for the public health and welfare, and Article I, Section 22 recognizes all Alaskans’ fundamental right to privacy. When read together, these provisions provide for a dual right to housing, encompassing both an affirmative right to adequate and affordable housing, …

Using Patient-Specific 3d-Printed C1-C2 Interfacet Spacers For The Treatment Of Type 1 Basilar Invagination: A Clinical Case Report, Tim T Bui, Alexander T Yahanda, Karan Joseph, Miguel Ruiz-Cardozo, Bernardo A De Monaco, Alexander Perdomo-Pantoja, Joshua P Koleske, Sean D Mcevoy, Camilo A Molina

2020-Current year OA Pubs

No abstract provided.

A Qualitative Exploration Of Paraprofesionals' Use Of Mobile Technology To Coordinate Behavioral Support, Sean Erreger

Social Work Doctoral Dissertations

Technology that is utilized to track and assess behavior is being used more frequently in social work practice. Social Workers frequently participate and lead organizations that provide services to individuals with intellectual and developmental disabilities. Direct Support Professionals (DSPs) and Registered Behavior Technicians (RBTs) face significant workforce challenges, but mobile technology may assist with reducing their administrative burden, assist in training needs, and increase the level of support felt by their supervisors. One of those technologies is the use of mobile devices to record behavior. The developmental disabilities field has started to implement the use of such mobile devices. The …

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LSU Journal of Energy Law and Resources

No abstract provided.

Coming Soon To A State Near You? Does Louisiana’S Public Trust Doctrine Encompass A Right To A “Clean And Healthful Environment?”, Ryan M. Seidemann

LSU Journal of Energy Law and Resources

No abstract provided.

Louisiana’S Neverland: Alternatives To Revising The Public Trust Doctrine Informed By Promising Tales Of Faith, Trust, And Pixie Dust, Madeline Kraus

LSU Journal of Energy Law and Resources

No abstract provided.

If You Give A Forced Labor System A Cookie: How Congress Can Enforce Conservation And Human Rights Laws In The Palm Oil Industry Through A Lacey Act Approach, Marissa Torres

LSU Journal of Energy Law and Resources

No abstract provided.

Walking The Tightrope: Louisiana’S Attempt To Balance State Regulation Authority Of Carbon Capture And Storage Projects With Local Parish Concerns, Sarah Miller

LSU Journal of Energy Law and Resources

No abstract provided.

“Waive” Goodbye To Special Treatment: The Unconstitutionality Of Section 209(B) Of The Clean Air Act In State Of Ohio V. Epa And How Congress Can Fix It, Macy Heroman

LSU Journal of Energy Law and Resources

No abstract provided.

The Impact Of The 2017 Square Footage Requirement On New Jersey Supplemental Nutrition Program For Women, Infants, And Children (Wic) Vendors, Carmelo Rodriguez

Walden Dissertations and Doctoral Studies

This study examined the impact of the 2017 New Jersey regulation requiring vendors to have 1,000 square feet of retail space in order to participate in the Supplemental Nutrition Program for Women, Infants, and Children (WIC) food program. Specifically, it examined vendors' role in developing the policy and their perspectives on its implementation. Previous research indicated improved policy outcomes by including policy targets in policy dialogue, but there was a lack of research exploring the experiences of vendors. Not known was how the policy affected WIC vendors, the essential frontline suppliers of nutritional foods to WIC participants. The purpose of …

Re: Medical Monitoring Working Group Meeting Minutes, Mike Mcanulty, Eric Hassler

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

The N-Pact Factor, Replication And Power Associated With Quantitative Research In Physical Activity And Health, Angelina Haidar, Jeffrey J. Martin, Adam J. Martin, Sarah Rogers, Fatemeh Dehghan, Eva Prokesova

International Journal of Physical Activity and Health

Physical Activity (PA) and health science researchers often face challenges related to sample size, which can impact the reliability and generalizability of study findings. The purpose of the current paper is to address these issues by discussing key statistical concepts: effect size and Type I and Type II errors, with a specific focus on examining statistical power and sample size using studies from the Disability and Health Journal (DHJ). We examined research articles published in DHJ over a 15-year period (2008–2022), covering 62 issues and analyzing a total of 1,177 articles. Our analysis revealed that the median sample sizes …

Atpase Level In Iraqi Diabetic Patients With And Without Diabetic Kidney Disease, Reham Khuldon Ibrahim, Kadhim K. Ghudhaib, Ali Abdulmajid Dyab Allawi

Baghdad Science Journal

Complications of diabetes have become one of the main problems that diabetics suffer from, especially during long periods. One of these complications is diabetic nephropathy, as both glomeruli and tubules are exposed to fibrosis due to diabetes. Recent years have witnessed great interest by researchers regarding diabetic nephropathy. This study aimed to determine the level of ATPase and some of the relevant biochemical factors in patients with diabetes and diabetic nephropathy compared with healthy controls. The study included 120 male and female (60 male and 60 female) ranging in age (30-65) years old. Ninety patients with type 2 diabetes are …

Note From The Editor

Alaska Law Review

No abstract provided.

Making Alaskans Whole: How Regulators Can Restore Trans-Alaska Pipeline System Lands And Recover Billions For The Public, Catherine H. Rocchi, Philip A. Wight, Michael Loughran

Alaska Law Review

This Article examines the dismantlement, removal, and restoration requirements associated with the Trans-Alaska Pipeline System (TAPS). These decommissioning obligations, rooted in the right-of-way lease agreements between state and federal agencies and the pipeline owners, require the lessees to remove pipeline infrastructure and restore Alaskan lands at the end of the pipeline’s useful life. Yet the regulatory structures governing TAPS decommissioning are deficient in several respects. Regulators have failed to safeguard decommissioning collections using a designated fund or a comprehensive liability regime. An opaque and overly permissive approach to transfers of ownership between the TAPS carriers has substituted private agreements for …

Feed It To The Ocean: The Federal Approach To Decommissioning In Alaska Native Climate Adaptation Projects, Sophia Tidler

Alaska Law Review

This Note calls on the Council on Environmental Quality (CEQ) to issue guidance clarifying that concurrent decommissioning is an in-scope “connected action” under the National Environmental Policy Act for relocation, managed retreat, and protect-in-place projects aimed at replacing infrastructure in environmentally threatened Alaska Native communities. In 2018, the Denali Commission completed the Final Environmental Impact Statement for Alaska’s first community-driven village relocation of the millennium, facilitating construction of essential infrastructure at Mertarvik, the relocation site for the village of Newtok. However, the Denali Commission chose to exclude a full-scale decommissioning plan for Newtok’s existing infrastructure. Today, more than seventy-three Alaska …

Complementarities In High School And College Investments, John Eric Humphries, Juanna Schrøter Joensen, Gregory Veramendi

Cowles Foundation Discussion Papers

This paper examines how high school specialization shapes college investment decisions and their subsequent returns through dynamic complementarities. Using Swedish administrative data, we estimate a dynamic Roy model that accounts for selection on multidimensional skills, family background, prior investments, and unobserved heterogeneity. We identify the model using rich skill measures and quasi-experimental variation in program popularity. For marginal students, STEM specialization in high school increases wages by 9%, with more than half this return attributed to dynamic complementarities that enhance the productivity of subsequent college investments. Consequently, we find that counterfactual policies encouraging high school STEM specialization generate twice the …

The Potential Mediating Role Of Perfectionistic Self-Presentation In The Relationship Between Other Stigma, Self-Stigma, And Attitudes Towards Mental Health Help-Seeking In Asian Americans, Trevor E. Taone

Clinical Psychology Dissertations

The importance of understanding why individuals decided to engage in mental health care cannot be overstated. This importance is further highlighted in the need to examine the different factors that may help researchers and clinicians to obtain more insight into why populations with a higher demand for mental health services, such as Asian Americans, possess negative attitudes toward seeking mental health care. Stigma has been identified as a significant barrier that influences these attitudes towards help-seeking. Other stigma and self-stigma, in particular, play an important role in understanding why individuals may possess negative views about mental health care help-seeking. With …

Cardiovascular Health In Cardiac Rehabilitation: Applying The American Heart Association Life's Simple 7 Framework In A Center-Based Cohort, Audry Chacin-Suarez, Tomoaki Hama, Matthew P. Johnson, Helayna Abraham, Thomas P. Olson, Laprincess C. Brewer

Einstein Health Papers

BACKGROUND: Cardiac rehabilitation (CR) is a comprehensive secondary cardiovascular disease program with structured lifestyle interventions to reduce morbidity and mortality. The American Heart Association cardiovascular health (CVH) framework measures health-promoting behaviors and clinical factors, but it has not been rigorously evaluated in the CR setting.

METHODS: This retrospective cohort study analyzed patients attending CR from January 2018 to September 2020. Patients were evaluated at baseline (pre-CR) and completion (post-CR) using 3 clinical factors (blood pressure, cholesterol, and hemoglobin A1c) and 4 health behaviors (smoking, body mass index, physical activity, and diet). CVH score was computed as a composite of each …

New Hampshire’S House Environment And Agriculture Committee Visits Unh, Mark Wanner

UNH Today Archive

No abstract provided.

Transient Quadriplegia With Albuminocytologic Dissociation: A Unique Presentation Of Suspected Guillain-Barré Syndrome, Ryan Nazari, Jonathan C. Hall

Student Publications

Guillan-Barré syndrome (GBS) is an autoimmune-mediated process that typically causes a progressive ascending paralysis that can lead to persistence of symptoms, permanent paralysis, and even death. While most cases follow a classical course with gradual progression of symptoms until eventual plateau, atypical and rapid onset clinical presentations can complicate differential diagnosis and diagnostic certainty, leading to late diagnosis by clinicians. A 35-year-old male with a history of intravenous (IV) methamphetamine use presented with a sudden onset and complete motor and sensory triplegia of the bilateral legs and left arm upon waking, which resolved shortly after hospital admission. After transfer for …

Potential Epigenetic Impacts Of Phytochemicals On Ruminant Health And Production: Connecting Lines Of Evidence, Sebastian P. Schreiber, Juan Villalba, Mirella L. Meyer-Ficca

Wildland Resources Student Research

The once mysterious “dark matter of nutrition”, comprising countless plant derived secondary compounds, also known as phytochemicals, is now understood to have significant and wide-ranging effects on consumers, including myriad health benefits in humans and livestock. The selective consumption of phytochemically rich and diverse plants, in appropriate doses, by ruminants represents an adaptive means of therapeutic and prophylactic self-medication. Due to their chemical structure, phytochemicals have long been recognized as antioxidants. However, the mechanisms that underlie numerous additional phytochemical-based health benefits are generally less understood. These effects (i.e., anti-inflammatory, immunomodulatory, and anticarcinogenic effects) are likely related to epigenetic processes. Evidence …

Slow-Growing Lung Mass In A Patient With Multiple Endocrine Neoplasia Type I: Consider Carcinoid Tumor, Ramin Talebi, Charalambos C. Solomides, Nathaniel R. Evans Iii, Gregory C. Kane

Division of Pulmonary, Allergy, and Critical Care Medicine Faculty Papers

A 23-year-old man with multiple endocrine neoplasia type 1 (MEN 1) with pancreatic tail masses and Cushing syndrome (status after transsphenoidal adenomectomy) presented with a slow-growing, asymptomatic right lower lung lobe mass confirmed to be an atypical carcinoid tumor by pathologic staging following successful basilar segmentectomy with mediastinal lymphadenectomy. Pulmonary carcinoid tumor (PCT) is a rare neoplasm in patients with MEN 1, but there is limited data on trends in atypical versus typical carcinoid tumors in these patients. This case emphasizes the need to characterize these trends given the implications for metastatic potential and 5-year survival, which can help guide …

Staff Education To Addressing Medication Nonadherence Amongst Patients With Mental Health Challenges, Euphemia Mah

Walden Dissertations and Doctoral Studies

Walden University College of Nursing This is to certify that the doctoral study by Euphemia Mah has been found to be complete and satisfactory in all respects, and that any and all revisions required by the review committee have been made. Review Committee Dr. Corinne Wheeler, Committee Chairperson, Nursing Faculty Dr. Robert McWhirt, Committee Member, Nursing Faculty Chief Academic Officer and Provost Sue Subocz, Ph.D. Walden University 2025 Summary Poor adherence to medication regimens among patients who have a mental illness leads to multiple adverse outcomes, which include symptom exacerbation, decreased quality of life, and repeated hospitalizations. To address this …

Nutrient Dynamics In Restored And Unrestored Urban Streams In The Piedmont Ecoregion Of South Carolina, Emily J. Jordan, Debabrata Sahoo, Calvin B. Sawyer, Jeremy W. Pike, Dara M. Park, Sarah A. White, Brian E. Haggard

Biological and Agricultural Engineering Faculty Publications and Presentations

The United States invests billions of dollars annually to perform stream restoration projects, yet few studies have investigated the effects this ecosystem manipulation has on nutrient cycling and associated water quality. Water quality improvement remains a substantial motivation for mitigating catchment-scale disturbances, especially in urban streams. Various urban land use practices impact the transfer and transport of nutrients such as soluble reactive phosphorus, ammonium, and nitrate plus nitrite from land into the streams and rivers. The uptake length (Sw), or the distance a dissolved nutrient travels downstream within a stream reach, can be measured using short-term nutrient injections, where shorter …

Supporting Achievement Motivation In Black And Latine Middle School Students: Development And Evaluation Of The Feasibility And Acceptability Of A Motivational Interviewing Intervention, Austin Roy Cole

USF Tampa Graduate Theses and Dissertations

Participation in accelerated high school curricula can provide substantive post-secondary benefits for students. However, participation continues to reflect disparate enrollment for Black and Latine students. Though organizations and legislatures have sought to improve Black and Latine student enrollment, the enrollment gap has not closed and there is little evidence of improving academic achievement for Black and Latine students beyond increased enrollment. Research shows that when students have their psychological needs of autonomy, competence, and relatedness met, as described by Self-Determination Theory, they demonstrate better academic outcomes and social-emotional development. Barriers reported by students of color reflect these psychological needs. Thus, …

A Community-Based Study To Investigate Persistent Ambient Odors In Childs Park, Fl, Gennaro Saliceto

USF Tampa Graduate Theses and Dissertations

For many years, residents in Childs Park, Saint Petersburg, Florida, have reported unpleasant odors. Although there have been prior efforts to address the issue, the odors continue to be a concern for the community, who worry about possible health implications. This research aimed to equip residents with information to address the issue by identifying the presence of airborne pollutants that generate odors, quantifying the concentrations of toxic organic pollutants, and exploring the sources and environmental conditions that contribute to odors and their perception.

To accomplish these aims, the study utilized different methods. First, two walking measurement campaigns were conducted to …